Sumin Kang PhD
- Department of Hematology and Medical Oncology
Professor
- (404) 778-1880
- smkang@emory.edu
- Kang lab website
-
Emory University
Hematology and Medical Oncology
1365C Clifton Rd NE, Winship Cancer Institute, Suite C3006
Academic Appointment
- Professor, Department of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute
Education
Degrees
- PhD from Yonsei University
- MS from Yonsei University
- BS from Seoul Women’s University
Research
Focus
- Main Focus of my research focuses on phosphor-proteomics based studies to elucidate signaling mechanisms underlying protein kinase-dependent oncogenesis and tumor metastasis; translational and preclinical studies using in vitro cell assays and in vivo mouse models of tumors and metastases to evaluate small molecule protein kinase inhibitors to treat human cancers.
Publications
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Succinyl-CoA ligase ADP-forming subunit beta promotes stress granule assembly to regulate redox and drive cancer metastasis.
Proc Natl Acad Sci U S A Volume: 120 Page(s): e2217332120
06/06/2023 Authors: Boese AC; Kang J; Hwang JS; Kim J; Eun K; Malin CM; Magliocca KR; Pan C; Jin L; Kang S -
EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer.
Cell Rep Volume: 41 Page(s): 111827
12/13/2022 Authors: Kang J; Chun J; Hwang JS; Pan C; Li J; Boese AC; Young I; Malin CM; Kang Y; Gibbons DL -
Metabolic inhibitor screening identifies dihydrofolate reductase as an inducer of the tumor immune escape mediator CD24.
Immunomedicine Volume: 2
12/01/2022 Authors: Boese AC; Hwang JS; Young I; Malin CM; Avalos V; Kang J; Kang S -
Cisplatin-mediated activation of glucocorticoid receptor induces platinum resistance via MAST1.
Nat Commun Volume: 12 Page(s): 4960
08/16/2021 Authors: Pan C; Kang J; Hwang JS; Li J; Boese AC; Wang X; Yang L; Boggon TJ; Chen GZ; Saba NF -
Mitochondrial metabolism-mediated redox regulation in cancer progression.
Redox Biol Volume: 42 Page(s): 101870
06/01/2021 Authors: Boese AC; Kang S -
A DGKA-cJUN-WEE1 signaling axis provides platinum resistance in ovarian cancer
Volume: 80
08/01/2020 Authors: Li J; Pan C; Boese AC; Umano A; Kang S -
Hsp90B protects MAST1 from CHIP-mediated ubiquitination and degradation providing cisplatin resistance
Volume: 80
08/01/2020 Authors: Pan C; Li J; Boese A; Kang S -
DGKA Provides Platinum Resistance in Ovarian Cancer Through Activation of c-JUN-WEE1 Signaling.
Clin Cancer Res Volume: 26 Page(s): 3843 - 3855
07/15/2020 Authors: Li J; Pan C; Boese AC; Kang J; Umano AD; Magliocca KR; Yang W; Zhang Y; Lonial S; Jin L -
New Approaches to SCLC Therapy: From the Laboratory to the Clinic.
J Thorac Oncol Volume: 15 Page(s): 520 - 540
04/01/2020 Authors: Poirier JT; George J; Owonikoko TK; Berns A; Brambilla E; Byers LA; Carbone D; Chen HJ; Christensen CL; Dive C -
Tumor Progression of Breast Cancer during Hyperinsulinemic Obesity.
Trends Mol Med Volume: 26 Page(s): 354 - 356
04/01/2020 Authors: Boese AC; Kang S