Publications

• Multi-niche human bone marrow on-a-chip for studying the interactions of adoptive CAR-T cell therapies with multiple myeloma.
  Biomaterials Volume: 316 Page(s): 123016
  05/01/2025 Authors: Ghoshal D; Petersen I; Ringquist R; Kramer L; Bhatia E; Hu T; Richard A; Park R; Corbin J; Agarwal S
• Rapid, Point-of-Care Bone Marrow Aspirate Adequacy Assessment Via Deep Ultraviolet Microscopy.
  Lab Invest Volume: 105 Page(s): 104102
  05/01/2025 Authors: Gorti V; Subramanian AR; Ojaghi A; Nsonwu-Farley J; Tran R; Williams EK; Torres O; Aljudi A; Aumann W; Robles FE
• Redefining hyperviscosity in acute leukemia: Potential implications for red cell transfusions in the microvasculature.
  Am J Hematol Volume: 99 Page(s): 1103 - 1107
  06/01/2024 Authors: Musick JO; Williams EK; Fibben KS; Zhang DY; Caruso C; Sakurai Y; Tran R; Kemp ML; Lam WA
• Incorporating Hemoglobin Levels to Map Leukostasis Risk in Acute Leukemia Using Microvasculature-on-Chip Technologies
  Volume: 136
  11/05/2020 Authors: Oakley J; Williams EK; Caruso C; Sakurai Y; Tran R; Lew G; Lam WA
• Scalable Biotransport-Mediated Platform (Proxim) Synergizes with Transduction-Enhancing Strategies to Maximize Gene Transfer
  Volume: 28 Page(s): 379 - 380
  04/28/2020 Authors: Tran R; Denning G; Spencer HT; Doering CB; Lam WA
• Optimizing Munc13-4 Expression from Lentiviral Vector Transduced Human T Cells
  Volume: 28 Page(s): 172 - 172
  04/28/2020 Authors: Takushi S; Tran R; Fedanov A; Doering CB; Chandrakasan S; Spencer HT
• Microfluidic Approach for Highly Efficient Viral Transduction.
  Methods Mol Biol Volume: 2097 Page(s): 55 - 65
  01/01/2020 Authors: Tran R; Lam WA
• A Scalable Microfluidic Platform to Enhance Transduction Efficiency and Reduce Viral Vector Usage
  Volume: 27 Page(s): 332 - 332
  04/22/2019 Authors: Tran R; Spencer HT; Doering CB; Lam WA
• A microengineered vascularized bleeding model that integrates the principal components of hemostasis.
  Nat Commun Volume: 9 Page(s): 509
  02/06/2018 Authors: Sakurai Y; Hardy ET; Ahn B; Tran R; Fay ME; Ciciliano JC; Mannino RG; Myers DR; Qiu Y; Carden MA
• Microvasculature-on-a-chip for the long-term study of endothelial barrier dysfunction and microvascular obstruction in disease.
  Nat Biomed Eng Volume: 2 Page(s): 453 - 463
  01/01/2018 Authors: Qiu Y; Ahn B; Sakurai Y; Hansen CE; Tran R; Mimche PN; Mannino RG; Ciciliano JC; Lamb TJ; Joiner CH
• Microfluidic Transduction Harnesses Mass Transport Principles to Enhance Gene Transfer Efficiency.
  Mol Ther Volume: 25 Page(s): 2372 - 2382
  10/04/2017 Authors: Tran R; Myers DR; Denning G; Shields JE; Lytle AM; Alrowais H; Qiu Y; Sakurai Y; Li WC; Brand O
• Single-platelet nanomechanics measured by high-throughput cytometry.
  Nat Mater Volume: 16 Page(s): 230 - 235
  02/01/2017 Authors: Myers DR; Qiu Y; Fay ME; Tennenbaum M; Chester D; Cuadrado J; Sakurai Y; Baek J; Tran R; Ciciliano JC
• Improving Lentiviral Transduction Efficiency with Microfluidic Systems
  Volume: 126
  12/03/2015 Authors: Tran R; Myers DR; Shields JE; Ahn B; Qiu Y; Hansen C; Sakurai Y; Moot R; Spencer HT; Doering CB
• Platelets and physics: How platelets "feel" and respond to their mechanical microenvironment.
  Blood Rev Volume: 29 Page(s): 377 - 386
  11/01/2015 Authors: Qiu Y; Ciciliano J; Myers DR; Tran R; Lam WA
• Platelet geometry sensing spatially regulates -granule secretion to enable matrix self-deposition.
  Blood Volume: 126 Page(s): 531 - 538
  07/23/2015 Authors: Sakurai Y; Fitch-Tewfik JL; Qiu Y; Ahn B; Myers DR; Tran R; Fay ME; Ding L; Spearman PW; Michelson AD
• Platelet Adhesion, Spreading and Activation Are Mediated By Mechanosensing of Matrix Stiffness
  Volume: 124
  12/06/2014 Authors: Qiu Y; Brown AC; Myers DR; Sakurai Y; Mannino R; Tran R; Ahn B; Hardy E; Kee MF; Kumar S
• Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation.
  Proc Natl Acad Sci U S A Volume: 111 Page(s): 14430 - 14435
  10/07/2014 Authors: Qiu Y; Brown AC; Myers DR; Sakurai Y; Mannino RG; Tran R; Ahn B; Hardy ET; Kee MF; Kumar S
• Factor XIII activity mediates red blood cell retention in venous thrombi.
  J Clin Invest Volume: 124 Page(s): 3590 - 3600
  08/01/2014 Authors: Aleman MM; Byrnes JR; Wang J-G; Tran R; Lam WA; Di Paola J; Mackman N; Degen JL; Flick MJ; Wolberg AS
• Simplified prototyping of perfusable polystyrene microfluidics.
  Biomicrofluidics Volume: 8 Page(s): 046501
  07/01/2014 Authors: Tran R; Ahn B; Myers DR; Qiu Y; Sakurai Y; Moot R; Mihevc E; Trent Spencer H; Doering C; A Lam W
• The platelet and the biophysical microenvironment: lessons from cellular mechanics.
  Thromb Res Volume: 133 Page(s): 532 - 537
  04/01/2014 Authors: Ciciliano JC; Tran R; Sakurai Y; Lam WA
• Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling.
  Blood Volume: 122 Page(s): 1695 - 1706
  09/05/2013 Authors: Chen Y; Aardema J; Kale S; Whichard ZL; Awomolo A; Blanchard E; Chang B; Myers DR; Ju L; Tran R
• Biomechanics of haemostasis and thrombosis in health and disease: from the macro- to molecular scale.
  J Cell Mol Med Volume: 17 Page(s): 579 - 596
  05/01/2013 Authors: Tran R; Myers DR; Ciciliano J; Trybus Hardy EL; Sakurai Y; Ahn B; Qiu Y; Mannino RG; Fay ME; Lam WA
• An "Endothelialized" Microfluidic System That Distinguishes Procoagulant Mechanisms in Arterial and Venous Thrombosis
  Volume: 120
  11/16/2012 Authors: Ahn B; Sakurai Y; Myers DR; Qiu Y; Hardy E; Tran R; Mannino R; Wolberg AS; Lam W
• Endothelialized microfluidics for studying microvascular interactions in hematologic diseases.
  J Vis Exp
  06/22/2012 Authors: Myers DR; Sakurai Y; Tran R; Ahn B; Hardy ET; Mannino R; Kita A; Tsai M; Lam WA