Publications

• Pasritamig, a First-in-Class, Bispecific T-Cell Engager Targeting Human Kallikrein 2, in Metastatic Castration-Resistant Prostate Cancer: A Phase I Study.
  J Clin Oncol Volume: 43 Page(s): 2515 - 2526
  08/01/2025 Authors: Stein MN; Vinceneux A; Robbrecht D; Doger B; Autio KA; Schweizer MT; Calvo E; Medina L; Van Dongen M; Deville J-L
• Intracranial and systemic progression on amivantamab in platinum-treated epidermal growth factor receptor exon 20 insertion-mutated advanced non-small cell lung cancer.
  Lung Cancer Volume: 205 Page(s): 108579
  07/01/2025 Authors: Leighl NB; Trigo J; Park K; Lee S-H; Girard N; Viteri S; Garrido P; Krebs MG; Thayu M; Knoblauch RE
• The LIN28B-let-7-PBK pathway is essential for group 3 medulloblastoma tumor growth and survival.
  Mol Oncol Volume: 17 Page(s): 1784 - 1802
  09/01/2023 Authors: Shahab SW; Roggeveen CM; Sun J; Kunhiraman H; McSwain LF; Juraschka K; Kumar SA; Saulnier O; Taylor MD; Schniederjan M
• Identification and targeting of protein tyrosine kinase 7 (PTK7) as an immunotherapy candidate for neuroblastoma.
  Cell Rep Med Volume: 4 Page(s): 101091
  06/20/2023 Authors: Lee JY; Jonus HC; Sadanand A; Branella GM; Maximov V; Suttapitugsakul S; Schniederjan MJ; Shim J; Ho A; Parwani KK
• Epigenetic regulator BMI1 promotes alveolar rhabdomyosarcoma proliferation and constitutes a novel therapeutic target.
  Mol Oncol Volume: 15 Page(s): 2156 - 2171
  08/01/2021 Authors: Shields CE; Potlapalli S; Cuya-Smith SM; Chappell SK; Chen D; Martinez D; Pogoriler J; Rathi KS; Patel SA; Oristian KM
• TARGETING THE RNA-BINDING PROTEIN LIN28B IN GROUP 3 MEDULLOBLASTOMA
  Volume: 23 Page(s): 8 - 8
  06/01/2021 Authors: Shahab S; Schnepp R; MacDonald T; Kenney A
• YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma.
  Cancer Res Volume: 80 Page(s): 4741 - 4753
  11/01/2020 Authors: Shim J; Lee JY; Jonus HC; Arnold A; Schnepp RW; Janssen KM; Maximov V; Goldsmith KC
• BMI1 constitutes a novel therapeutic vulnerability in fusion-positive rhabdomyosarcoma
  Volume: 80 Page(s): 67 - 68
  07/01/2020 Authors: Shields CE; Cuya SM; Chappell S; Rathi K; Patel S; Potlapalli S; Schnepp RW
• A LIN28B-PDZ kinase axis promotes neuroblastoma metastasis
  Volume: 80 Page(s): 104 - 104
  07/01/2020 Authors: Chen D; Cox J; Annam J; Weingart M; Essien G; Rathi K; Khurana P; Cuya S; Harenza JL; Bosse K
• RNA Binding Protein LIN28B: a prime time player shaping neuroblastoma aggression and metastasis.
  Oncoscience Volume: 7 Page(s): 52 - 56
  07/01/2020 Authors: Chen D; Schnepp RW
• Limited antitumor activity of combined BET and MEK inhibition in neuroblastoma.
  Pediatr Blood Cancer Volume: 67 Page(s): e28267
  06/01/2020 Authors: Healy JR; Hart LS; Shazad AL; Gagliardi ME; Tsang M; Elias J; Ruden J; Farrel A; Rokita JL; Li Y
• BMI1 IS A THERAPEUTIC TARGET IN RHABDOMYOSARCOMA
  Volume: 67 Page(s): S124 - S124
  06/01/2020 Authors: Shields C; Cuya S; Potlapalli S; Chappell S; Chen J; Rathi K; Patel S; Schnepp R
• MSI2 IS A NOVEL ONCOGENIC DRIVER IN NEUROBLASTOMA
  Volume: 67 Page(s): S118 - S118
  06/01/2020 Authors: Pilgrim A; Cuya S; Chen D; Rokita JL; Rathi K; Li D; Mukarram M; Schnepp R
• LIN28B-PDZ BINDING KINASE SIGNALING PROMOTES NEUROBLASTOMA METASTASIS
  Volume: 67 Page(s): S148 - S149
  06/01/2020 Authors: Chen J; Cox J; Annam J; Weingart M; Essien G; Rathi K; Rokita JL; Khurana P; Cuya S; Pilgrim A
• LIN28B promotes neuroblastoma metastasis and regulates PDZ binding kinase.
  Neoplasia Volume: 22 Page(s): 231 - 241
  04/24/2020 Authors: Chen D; Cox J; Annam J; Weingart M; Essien G; Rathi KS; Rokita JL; Khurana P; Cuya SM; Bosse KR
• Targeting epigenetic regulator BMI-1 in alveolar rhabdomyosarcoma
  Volume: 79
  07/01/2019 Authors: Shields CE; Cuya SM; Chappell SK; Rathi K; Patel S; Potlapalli S; Schnepp RW
• Defining an ELAVL1-Musashi 2 signaling cascade in neuroblastoma tumorigenesis
  Volume: 79
  07/01/2019 Authors: Cuya SM; Pilgrim A; Rathi K; Chen D; Schnepp R
• Defining the role of the RNA-binding protein MSI2 in neuroblastoma
  Volume: 79
  07/01/2019 Authors: Pilgrim A; Cuya S; Chen D; Schnepp R
• A LIN28B-PBK Axis promotes neuroblastoma dissemination and aggression
  Volume: 79
  07/01/2019 Authors: Chen D; Cox J; Annam J; Weingart M; Essien G; Rathi K; Khurana P; Cuya SM; Schnepp RW
• Antitumor activity and sensitivity evaluation of novel BET inhibitors in neuroblastoma
  Volume: 14
  11/01/2016 Authors: Healy JR; Schnepp RW; Hart LS; Raman P; Danielson L; Russell M; Khurana P; Gagliardi M; Kinsey RM; Wyce A
• LIN28B: an orchestrator of oncogenic signaling in neuroblastoma.
  Cell Cycle Volume: 15 Page(s): 772 - 774
  01/01/2016 Authors: Schnepp RW; Diskin SJ
• A LIN28B-RAN-AURKA Signaling Network Promotes Neuroblastoma Tumorigenesis.
  Cancer Cell Volume: 28 Page(s): 599 - 609
  11/09/2015 Authors: Schnepp RW; Khurana P; Attiyeh EF; Raman P; Chodosh SE; Oldridge DA; Gagliardi ME; Conkrite KL; Asgharzadeh S; Seeger RC
• Antitumor activity and sensitivity evaluation of novel BET inhibitors in neuroblastoma
  Volume: 13
  10/01/2015 Authors: Healy JR; Schnepp RW; Hart LS; Raman P; Danielson L; Russell M; Khurana P; Gagliardi M; Kinsey RM; Wyce A
• Improving Patient Outcomes With Cancer Genomics: Unique Opportunities and Challenges in Pediatric Oncology.
  JAMA Volume: 314 Page(s): 881 - 883
  09/01/2015 Authors: Schnepp RW; Bosse KR; Maris JM
• A LIN28B/RAN/AURKA signaling network promotes neuroblastoma tumorigenesis
  Volume: 75
  08/01/2015 Authors: Schnepp RW; Khurana P; Attiyeh EF; Chodosn S; Raman P; Oldridge DA; Gagliardi ME; Conkrite K; Asgharzadeh S; Seeger RC
• Defining the antitumor activity and sensitivity profiles of BET inhibitors in neuroblastoma
  CANCER RESEARCH Volume: 74
  10/01/2014 Authors: Schnepp R; Hart L; Raman P; Danielson L; Gagliardi M; Kinsey R; Wyce A; Barbash O; Tummino P; Chesler L
• Dual CDK4/CDK6 inhibition induces cell-cycle arrest and senescence in neuroblastoma.
  Clin Cancer Res Volume: 19 Page(s): 6173 - 6182
  11/15/2013 Authors: Rader J; Russell MR; Hart LS; Nakazawa MS; Belcastro LT; Martinez D; Li Y; Carpenter EL; Attiyeh EF; Diskin SJ
• The role of LIN28B and RAN in promoting neuroblastoma tumorigenesis
  Volume: 73
  04/15/2013 Authors: Schnepp RW; Attiyeh EF; Gagliardi ME; Chodosh S; Maris JM; Diskin SJ
• CDK4/CDK6 inhibition is potently active in a definable subset of human neuroblastomas.
  Volume: 73
  04/15/2013 Authors: Rader J; Hart L; Russell M; Nakazawa M; Belcastro L; Martinez D; Carpenter E; Kim S; Parasuraman S; Caponigro G
• Targeting MYCN: a good BET for improving neuroblastoma therapy?
  Cancer Discov Volume: 3 Page(s): 255 - 257
  03/01/2013 Authors: Schnepp RW; Maris JM
• Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma.
  Nat Genet Volume: 44 Page(s): 1126 - 1130
  10/01/2012 Authors: Diskin SJ; Capasso M; Schnepp RW; Cole KA; Attiyeh EF; Hou C; Diamond M; Carpenter EL; Winter C; Lee H
• New neuroblastoma susceptibility loci at 6q21 within HACE1 and LIN28B
  CANCER RESEARCH Volume: 72
  04/15/2012 Authors: Diskin SJ; Capasso M; Latorre V; Schnepp R; Attiyeh EF; Diamond M; Hou C; Carpenter EL; Lee H; Cole KA
• Common variation at BARD1 results in the expression of an oncogenic isoform that influences neuroblastoma susceptibility and oncogenicity.
  Cancer Res Volume: 72 Page(s): 2068 - 2078
  04/15/2012 Authors: Bosse KR; Diskin SJ; Cole KA; Wood AC; Schnepp RW; Norris G; Nguyen LB; Jagannathan J; Laquaglia M; Winter C
• GERMLINE VARIATIONS ARE ASSOCIATED WITH SUSCEPTIBILITY TO HIGH-RISK NEUROBLASTOMA AND IDENTIFY PATHWAYS WITH GAIN OF FUNCTION
  PEDIATRIC BLOOD & CANCER Volume: 57 Page(s): 724 - 724
  11/01/2011 Authors: Wood A; Bosse K; Wang K; Diskin S; Schnepp R; Diamond M; Attiyeh E; Morozova O; Pugh T; Mosse Y
• Integrative genomics identifies LMO1 as a neuroblastoma oncogene.
  Nature Volume: 469 Page(s): 216 - 220
  01/13/2011 Authors: Wang K; Diskin SJ; Zhang H; Attiyeh EF; Winter C; Hou C; Schnepp RW; Diamond M; Bosse K; Mayes PA
• Menin-mediated caspase 8 expression in suppressing multiple endocrine neoplasia type 1.
  J Biol Chem Volume: 282 Page(s): 31332 - 31340
  10/26/2007 Authors: La P; Yang Y; Karnik SK; Silva AC; Schnepp RW; Kim SK; Hua X
• Tumor suppressor menin: the essential role of nuclear localization signal domains in coordinating gene expression.
  Oncogene Volume: 25 Page(s): 3537 - 3546
  06/15/2006 Authors: La P; Desmond A; Hou Z; Silva AC; Schnepp RW; Hua X
• Mutation of tumor suppressor gene Men1 acutely enhances proliferation of pancreatic islet cells.
  Cancer Res Volume: 66 Page(s): 5707 - 5715
  06/01/2006 Authors: Schnepp RW; Chen Y-X; Wang H; Cash T; Silva A; Diehl JA; Brown E; Hua X
• Cardiorespiratory adjustments of homing pigeons to steady wind tunnel flight.
  J Exp Biol Volume: 208 Page(s): 3109 - 3120
  08/01/2005 Authors: Peters GW; Steiner DA; Rigoni JA; Mascilli AD; Schnepp RW; Thomas SP
• Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors.
  Proc Natl Acad Sci U S A Volume: 102 Page(s): 749 - 754
  01/18/2005 Authors: Milne TA; Hughes CM; Lloyd R; Yang Z; Rozenblatt-Rosen O; Dou Y; Schnepp RW; Krankel C; Livolsi VA; Gibbs D
• Direct binding of DNA by tumor suppressor menin.
  J Biol Chem Volume: 279 Page(s): 49045 - 49054
  11/19/2004 Authors: La P; Silva AC; Hou Z; Wang H; Schnepp RW; Yan N; Shi Y; Hua X
• Functional interaction between tumor suppressor menin and activator of S-phase kinase.
  Cancer Res Volume: 64 Page(s): 6791 - 6796
  09/15/2004 Authors: Schnepp RW; Hou Z; Wang H; Petersen C; Silva A; Masai H; Hua X
• Tumor suppressor menin regulates expression of insulin-like growth factor binding protein 2.
  Endocrinology Volume: 145 Page(s): 3443 - 3450
  07/01/2004 Authors: La P; Schnepp RW; D Petersen C; C Silva A; Hua X
• Menin induces apoptosis in murine embryonic fibroblasts
  Volume: 255 Page(s): 721 - 721
  06/01/2004 Authors: Schnepp RW; Mao H; Sykes SM; Zong WX; Silva A; La P; Hua X
• Tumor-suppressor menin regulates expression of insulin-like growth factor-binding protein 2 (IGFBP-2)
  Volume: 255 Page(s): 722 - 722
  06/01/2004 Authors: La P; Schnepp RW; Petersen CD; Silva AC; Hua X
• Menin induces apoptosis in murine embryonic fibroblasts.
  J Biol Chem Volume: 279 Page(s): 10685 - 10691
  03/12/2004 Authors: Schnepp RW; Mao H; Sykes SM; Zong W-X; Silva A; La P; Hua X
• Menin associates with FANCD2, a protein involved in repair of DNA damage.
  Cancer Res Volume: 63 Page(s): 4204 - 4210
  07/15/2003 Authors: Jin S; Mao H; Schnepp RW; Sykes SM; Silva AC; D'Andrea AD; Hua X
• Fusion proteins of retinoid receptors antagonize TGF-beta-induced growth inhibition of lung epithelial cells.
  Oncogene Volume: 22 Page(s): 198 - 210
  01/16/2003 Authors: La P; Morgan TA; Sykes SM; Mao H; Schnepp RW; Petersen CD; Hua X
• A tumor-suppressing duo: TGFbeta and activin modulate a similar transcriptome.
  Cancer Biol Ther Volume: 2 Page(s): 171 - 172
  01/01/2003 Authors: Schnepp R; Hua X
• Hop is an unusual homeobox gene that modulates cardiac development.
  Cell Volume: 110 Page(s): 713 - 723
  09/20/2002 Authors: Chen F; Kook H; Milewski R; Gitler AD; Lu MM; Li J; Nazarian R; Schnepp R; Jen K; Biben C
• Analysis and knockout of Toto, a novel homeobox gene in early cardiac development
  Volume: 104 Page(s): 75 - 75
  10/23/2001 Authors: Chen F; Nazarian R; Milewski RC; Schnepp RW; Chi NC; Lu MM; Epstein JA