Richard Castillo
- Department of Radiation Oncology
Professor
Overview
An ABR board certified medical physicist, Dr. Castillo has expertise in image-guided, and adaptive radiation therapy, the use of deformable image registration in medical image analysis, and quantitative methods for lung function imaging from CT.
Dr. Castillo is a professor of medical physics in the Department of Radiation Oncology at Emory University School of Medicine. He serves as assistant dean of equity, engagement and belonging in the Office of Equity and Inclusion, driving progress in the office's strategic priorities, primarily growing the innovation and discovery portfolio.
Dr. Castillo has previously served as principal investigator for an NIH Research Scientist Development Award (K01), and currently is co-investigator on an ongoing clinical trial (NCT02528942) prospectively evaluating the safety, feasibility, and preliminary efficacy of 4DCT-ventilation functional avoidance planning. As part of his PhD research, Dr. Castillo founded The Deformable Image Registration Laboratory website in 2009, and continues to maintain and support its function as a public repository for reference image data and image analysis software for quantitative clinical evaluation of deformable image registration.
Dr. Castillo is a Fellow and an active member of the American Association of Physicists in Medicine (AAPM), and currently sits on the AAPM's Diversity and Inclusion subcommittee. He also actively serves as associate senior editor for the International Journal of Radiation Oncology, Biology, Physics.
Academic Appointment
- Professor, Department of Radiation Oncology, Emory University School of Medicine
Education
Degrees
- PhD from University of Texas Graduate School of Biomedical Sciences
- MS from University of Texas Graduate School of Biomedical Sciences
Research
Focus
-
Deformable image registration in medical image analysis
Dr. Castillo's research is largely focused on the use of deformable image registration in medical image analysis, for purposes of guiding personalized delivery and treatment adaptation in radiotherapy of thoracic malignancies.
Publications
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Comprehensive clinical evaluation of novel 4DCT-based lung function imaging methods.
J Appl Clin Med Phys Page(s): e70088
04/08/2025 Authors: Golkar E; Neupane T; Wilson L; Kwak J; Castillo R; Castillo E; Vinogradskiy Y -
Patient-Reported Outcomes: Comparing Functional Avoidance and Standard Thoracic Radiation Therapy in Lung Cancer.
JCO Clin Cancer Inform Volume: 9 Page(s): e2400202
02/01/2025 Authors: Poiset SJ; Lombardo J; Castillo E; Castillo R; Jones B; Miften M; Kavanagh B; Dicker AP; Boyle C; Simone NL -
Perfusion estimation from dynamic non-contrast computed tomography using self-supervised learning and a physics-inspired U-net transformer architecture.
Int J Comput Assist Radiol Surg
01/20/2025 Authors: Liu Y-K; Cisneros J; Nair G; Stevens C; Castillo R; Vinogradskiy Y; Castillo E -
TriSwinUNETR lobe segmentation model for computing DIR-free CT-ventilation.
Front Oncol Volume: 15 Page(s): 1475133
01/01/2025 Authors: Nomura GRO; Luong AT; Prakash A; Alemand A; Bhowmick T; Ali A; Ren J; Rehani B; Nair G; Castillo R -
Prospective Trial of Functional Lung Avoidance Radiation Therapy for Lung Cancer: Quality of Life Report.
Int J Radiat Oncol Biol Phys Volume: 120 Page(s): 593 - 602
10/01/2024 Authors: Lombardo J; Castillo E; Castillo R; Miller R; Jones B; Miften M; Kavanagh B; Dicker A; Boyle C; Leiby B -
Women in the Medical Physics Workforce: Insights from Membership Trends of the American Association of Physicists in Medicine, 1993 to 2023.
Int J Radiat Oncol Biol Phys Volume: 119 Page(s): 1336 - 1343
08/01/2024 Authors: Rankin J; Bedrava J; Covington E; Johnson JL; Pollard-Larkin J; Schipper MJ; Castillo R; Woodward M; Xing Y-H; Paradis KC -
Systematic Evaluation of the Impact of Lung Segmentation Methods on 4-Dimensional Computed Tomography Ventilation Imaging Using a Large Patient Database.
Int J Radiat Oncol Biol Phys Volume: 118 Page(s): 242 - 252
01/01/2024 Authors: Chen Y; Pahlavian SH; Jacobs P; Neupane T; Forghani-Arani F; Castillo E; Castillo R; Vinogradskiy Y -
Evaluation of variables predicting PFT changes for lung cancer patients treated on a prospective 4DCT-ventilation functional avoidance clinical trial.
Radiother Oncol Volume: 187 Page(s): 109821
10/01/2023 Authors: Ghassemi N; Castillo R; Castillo E; Jones BL; Miften M; Kavanagh B; Werner-Wasik M; Miller R; Barta JA; Grills I -
Cardiac metabolic changes on 18 F-positron emission tomography after thoracic radiotherapy predict for overall survival in esophageal cancer patients.
J Appl Clin Med Phys Volume: 24 Page(s): e13552
09/01/2023 Authors: Zakem SJ; Jones B; Castillo R; Castillo E; Miften M; Goodman KA; Schefter T; Olsen J; Vinogradskiy Y -
Cardiac motion and its dosimetric impact during radioablation for refractory ventricular tachycardia.
J Appl Clin Med Phys Volume: 24 Page(s): e13925
06/01/2023 Authors: Harms J; Schreibmann E; Mccall NS; Lloyd MS; Higgins KA; Castillo R