School of Medicine Homepage
Emory University Shield
  • About
    • Our Vision
    • Academic Departments
    • Our Leadership
    • Health Care Partnerships
    • Diversity, Equity, & Inclusion
    • Location
    • Supporting Our People
    • Our Faculty
    • History
    • News
    • Events
    • Contact Us
  • Education
    • Degree and Certificate Programs
    • Academic Departments
    • Residents & Fellows
    • Postdoctoral Training
    • Continuing Medical Education
    • Admissions
    • Cost and Financial Aid
    • Student Resources
  • Research
    • Research Innovation
    • Conducting Research
    • Core Facilities
    • Research Centers
    • Research Training
    • Academic Departments
    • Find a Researcher
    • Research News
  • Clinical Experience
    • Where We Work
    • Caring for a Diverse Population
    • Faculty Clinical Experience
    • Advanced Patient Care
    • Academic Departments
    • Community Learning
  • Giving
  • Directory

Directory section navigation

  • Faculty Profiles

Emory University School of Medicine

  • About
    • Sub link
      Our Vision
    • Sub link
      Academic Departments
    • Sub link
      Our Leadership
    • Sub link
      Health Care Partnerships
    • Sub link
      Diversity, Equity, & Inclusion
    • Sub link
      Location
    • Sub link
      Supporting Our People
    • Sub link
      Our Faculty
    • Sub link
      History
    • Sub link
      News
    • Sub link
      Events
    • Sub link
      Contact Us
  • Education
    • Sub link
      Degree and Certificate Programs
    • Sub link
      Academic Departments
    • Sub link
      Residents & Fellows
    • Sub link
      Postdoctoral Training
    • Sub link
      Continuing Medical Education
    • Sub link
      Admissions
    • Sub link
      Cost and Financial Aid
    • Sub link
      Student Resources
  • Research
    • Sub link
      Research Innovation
    • Sub link
      Conducting Research
    • Sub link
      Core Facilities
    • Sub link
      Research Centers
    • Sub link
      Research Training
    • Sub link
      Academic Departments
    • Sub link
      Find a Researcher
    • Sub link
      Research News
  • Clinical Experience
    • Sub link
      Where We Work
    • Sub link
      Caring for a Diverse Population
    • Sub link
      Faculty Clinical Experience
    • Sub link
      Advanced Patient Care
    • Sub link
      Academic Departments
    • Sub link
      Community Learning
  • Giving
  • Directory
  • Home School of Medicine Home
  • Directory

Profile

Paul Dawson

  • Department of Pediatrics
    Professor
  • (404) 727-7083
  • paul.dawson@emory.edu
  • Pediatric Research Alliance Faculty Page
  • Emory University, Atlanta
    Pediatrics
    1760 Haygood Drive, Suite E220, #E206
Head shot of Paul Dawson

Overview

Dr. Dawsons research is focused on elucidating the physiologic and molecular mechanisms controlling bile acid homeostasis and their relationship to the pathogenesis of disease. The major goals are to understand how dysfunction of the gut-liver axis contributes to hepatic, gastrointestinal, and metabolic diseases and to exploit those insights to develop new preventative measures and therapies. These efforts include investigating the gut microbiotas role and its untapped therapeutic potential. In 2014, Dr. Dawson moved with along his research group to Emory University to further pursue these goals. The scope of the health problems studied range from rare monogenic intestinal and liver disorders (Primary Bile Acid Malabsorption, Progressive Familial Intrahepatic Cholestasis) to Non-alcoholic Fatty Liver Disease (the most common liver abnormality in children). Toward that end, the Lab utilizes a wide variety of approaches including Genomics, Metabolomics, Gnotobiotics, and Novel Mouse Models.

Academic Appointment

  • Professor, Pediatrics, Emory University

Education

Degrees

  • PhD from Stony Brook University, Stony Brook
  • BS from University of Florida, Gainesville

Research

Publications

  • Erratum to: 'Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis' [J Hepatol (2024) 80:268-281].
    J Hepatol Volume: 82 Page(s): 1140
    06/01/2025 Authors: Ghallab A; Gonzlez D; Strngberg E; Hofmann U; Myllys M; Hassan R; Hobloss Z; Brackhagen L; Begher-Tibbe B; Duda JC
  • Enteronephrohepatic Circulation of Bile Acids and Therapeutic Potential of Systemic Bile Acid Transporter Inhibitors.
    J Hepatol
    05/23/2025 Authors: Ghallab A; Mandorfer M; Stirnimann G; Geyer J; Lindstrm E; Luedde T; van der Merwe S; Rashidi-Alavijeh J; Schmidt H; Karpen SJ
  • Hepatic bile acid accretion correlates with cholestatic liver injury and therapeutic response in Cyp2c70 knockout mice with a humanized bile acid composition.
    Am J Physiol Gastrointest Liver Physiol Volume: 327 Page(s): G789 - G809
    12/01/2024 Authors: Klindt C; Truong JK; Bennett AL; Pachura KJ; Herebian D; Mayatepek E; Luedde T; Ebert M; Karpen SJ; Dawson PA
  • Metabolic immaturity and breastmilk bile acid metabolites are central determinants of heightened newborn vulnerability to norovirus diarrhea.
    Cell Host Microbe Volume: 32 Page(s): 1488 - 1501.e5
    09/11/2024 Authors: Peiper AM; Morales Aparicio J; Hu Z; Phophi L; Helm EW; Rubinstein RJ; Phillips M; Williams CG; Subramanian S; Cross M
  • BiliQML: a supervised machine-learning model to quantify biliary forms from digitized whole slide liver histopathological images.
    Am J Physiol Gastrointest Liver Physiol Volume: 327 Page(s): G1 - G15
    07/01/2024 Authors: Hellen DJ; Fay ME; Lee DH; Klindt-Morgan C; Bennett A; Pachura KJ; Grakoui A; Huppert SS; Dawson PA; Lam WA
  • Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis.
    J Hepatol Volume: 80 Page(s): 268 - 281
    02/01/2024 Authors: Ghallab A; Gonzlez D; Strngberg E; Hofmann U; Myllys M; Hassan R; Hobloss Z; Brackhagen L; Begher-Tibbe B; Duda JC
  • Quantifying Forms and Functions of Enterohepatic Bile Acid Pools in Mice.
    Cell Mol Gastroenterol Hepatol Volume: 18 Page(s): 101392
    01/01/2024 Authors: Sudo K; Delmas-Eliason A; Soucy S; Barrack KE; Liu J; Balasubramanian A; Shu CJ; James MJ; Hegner CL; Dionne HD
  • Validation of NBD-coupled taurocholic acid for intravital analysis of bile acid transport in liver and kidney of mice.
    EXCLI J Volume: 23 Page(s): 1330 - 1352
    01/01/2024 Authors: Ghallab A; Kunz S; Drossel C; Billo V; Friebel A; Georg M; Gttlich R; Hobloss Z; Hassan R; Myllys M
  • Farnesoid X receptor enhances epithelial ACE2 expression and inhibits virally induced IL-6 secretion: implications for intestinal symptoms of SARS-CoV-2.
    Am J Physiol Gastrointest Liver Physiol Volume: 325 Page(s): G446 - G452
    11/01/2023 Authors: Smyth JS; Truong JK; Rao A; Lin R; Foulke-Abel J; Adorini L; Donowitz M; Dawson PA; Keely SJ
  • The Concise Guide to PHARMACOLOGY 2023/24: Transporters.
    Br J Pharmacol Volume: 180 Suppl 2 Page(s): S374 - S469
    10/01/2023 Authors: Alexander SPH; Fabbro D; Kelly E; Mathie AA; Peters JA; Veale EL; Armstrong JF; Faccenda E; Harding SD; Davies JA
  • Combination of Ileal bile acid transporter inhibitor and a nonsteroidal Farnesoid X receptor agonist for reversal of cholestatic liver injury in Cyp2c70 KO mice with a humanized bile acid composition
    Volume: 78 Page(s): S415 - S416
    06/01/2023 Authors: Klindt-Morgan C; Truong J; Bennett A; Pachura K; Herebian D; Mayatepek E; Karpen SJ; Dawson P
  • Inhibition of the renal apical sodium-dependent bile acid transporter prevents cholemic nephropathy
    Volume: 78 Page(s): S940 - S941
    06/01/2023 Authors: Ghallab A; Gonzalez D; Strangberg E; Hofmann U; Myllys M; Hassan R; Luedde T; Akerblad P; Mattsson J; Marschall H-U
  • Liver-restricted deletion of the biliary atresia candidate gene Pkd1l1 causes bile duct dysmorphogenesis and ciliopathy.
    Volume: 77 Page(s): 1274 - 1286
    04/01/2023 Authors: Hellen DJ; Bennett A; Malla S; Klindt C; Rao A; Dawson PA; Karpen SJ
  • Active enterohepatic cycling is not required for the choleretic actions of 24-norUrsodeoxycholic acid in mice.
    JCI Insight Volume: 8
    03/22/2023 Authors: Truong JK; Li J; Li Q; Pachura K; Rao A; Gumber S; Fuchs CD; Feranchak AP; Karpen SJ; Trauner M
  • DEVELOPMENT OF A HUMANIZED MOUSE MODEL OF CHOLESTATIC SICKLE CELL DISEASE
    Volume: 76 Page(s): S1025 - S1026
    10/01/2022 Authors: Michael A; Dawson PA; Karpen SJ; Archer DR
  • Glial cell derived neurotrophic factor prevents western diet and palmitate-induced hepatocyte oxidative damage and death through SIRT3.
    Sci Rep Volume: 12 Page(s): 15838
    09/23/2022 Authors: Mwangi SM; Li G; Balasubramaniam A; Merlin D; Dawson PA; Jang YC; Hart CM; Czaja MJ; Srinivasan S
  • Ileal bile acid transporter inhibition in Cyp2c70 KO mice ameliorates cholestatic liver injury.
    J Lipid Res Volume: 63 Page(s): 100261
    09/01/2022 Authors: Truong JK; Bennett AL; Klindt C; Donepudi AC; Malla SR; Pachura KJ; Zaufel A; Moustafa T; Dawson PA; Karpen SJ
  • Fat Malabsorption and Ursodeoxycholic Acid Treatment in Children With Reduced Organic Solute Transporter- (SLC51A) Expression.
    JPGN Rep Volume: 3 Page(s): e229
    08/01/2022 Authors: Tronstad RR; Berland S; Tjora E; El Jellas K; Aukrust I; Kristensen K; Tveitnes D; Molven A; Marschall H-U; Rao A
  • Inhibition of Ileal Bile Acid Transport is Protective Against Cholestatic Liver Injury in Cyp2c70-/- Mice with Humanized Bile Acid Composition.
    Volume: 36 Suppl 1
    05/01/2022 Authors: Truong JK; Donepudi A; Bennett A; Malla S; Zaufel A; Pachura K; Hellen D; Moustafa T; Dawson P; Karpen S
  • DUAL ACTING ILEAL/RENAL-LIVER BILE ACID TRANSPORTER INHIBITORS SIGNIFICANTLY INCREASE URINARY EXCRETION OF NON-SULFATED BILE ACIDS IN A DIETHOXY-CARBONYL-DIHYDROCOLLIDINE-INDUCED MOUSE MODEL OF CHOLESTASIS
    Volume: 162 Page(s): S1182 - S1183
    05/01/2022 Authors: Rao A; Pachura K; Strangberg E; Gillberg P-G; Uzelac I; Starke I; Bonn B; Mattsson JP; Akerblad P; Straniero S
  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters.
    Br J Pharmacol Volume: 178 Suppl 1 Page(s): S412 - S513
    10/01/2021 Authors: Alexander SP; Kelly E; Mathie A; Peters JA; Veale EL; Armstrong JF; Faccenda E; Harding SD; Pawson AJ; Southan C
  • SPECIES-DEPENDENT DIFFERENCES IN RESPONSE TO SODIUM TAUROCHOLATE COTRANSPORTING POLYPEPTIDE INHIBITION: TRANSLATIONAL RELEVANCE TO HUMAN
    Volume: 74 Page(s): 519A - 520A
    10/01/2021 Authors: Lindstrom E; Gillberg P-G; Uzelac I; Starke I; Bonn B; Strangberg E; Mattsson J; Akerblad P; Pal R; Gaur A
  • PRECLINICAL CHARACTERIZATION OF THE NOVEL, ORALLY BIOAVAILABLE HEPATITIS B VIRAL ENTRY INHIBITOR A2342
    Volume: 74 Page(s): 512A - 513A
    10/01/2021 Authors: Lindstrom E; Gillberg P-G; Uzelac I; Starke I; Bonn B; Strangberg E; Mattsson J; Akerblad P; Pal R; Gaur A
  • Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions.
    Biochim Biophys Acta Mol Basis Dis Volume: 1867 Page(s): 166153
    08/01/2021 Authors: Zaufel A; van de Wiel SMW; Yin L; Fauler G; Chien D; Dong X; Gilmer JF; Truong JK; Dawson PA; van de Graaf SFJ
  • Craniofacial features of 3q29 deletion syndrome: Application of next-generation phenotyping technology.
    Am J Med Genet A Volume: 185 Page(s): 2094 - 2101
    07/01/2021 Authors: Mak BC; Sanchez Russo R; Gambello MJ; Fleischer N; Black ED; Leslie E; Murphy MM; Emory 3q29 Project; Mulle JG
  • Convergent and distributed effects of the 3q29 deletion on the human neural transcriptome.
    Transl Psychiatry Volume: 11 Page(s): 357
    06/15/2021 Authors: Sefik E; Purcell RH; Emory 3q29 Project; Walker EF; Bassell GJ; Mulle JG
  • Deep phenotyping in 3q29 deletion syndrome: recommendations for clinical care.
    Genet Med Volume: 23 Page(s): 872 - 880
    05/01/2021 Authors: Sanchez Russo R; Gambello MJ; Murphy MM; Aberizk K; Black E; Burrell TL; Carlock G; Cubells JF; Epstein MT; Espana R
  • DISCOVERY AND CHARACTERIZATION OF NOVEL BILE ACID TRANSPORTER INHIBITORS WITH POTENTIAL FOR TREATMENT OF LIVER DISEASES
    Volume: 72 Page(s): 226A - 227A
    11/01/2020 Authors: Gillberg P-G; Lindstrom E; Akerblad P; Rao A; Straniero S; Strangberg E; Starke I; Kulkarni S; Rudling M; Angelin B
  • The Beneficial Effects of Apical Sodium-Dependent Bile Acid Transporter Inactivation Depend on Dietary Fat Composition.
    Mol Nutr Food Res Volume: 64 Page(s): e2000750
    10/20/2020 Authors: van de Peppel IP; Rao A; Dommerholt MB; Bongiovanni L; Thomas R; de Bruin A; Karpen SJ; Dawson PA; Verkade HJ; Jonker JW
  • Comprehensive phenotyping of neuropsychiatric traits in a multiplex 3q29 deletion family: a case report.
    BMC Psychiatry Volume: 20 Page(s): 184
    04/22/2020 Authors: Murphy MM; Burrell TL; Cubells JF; Epstein MT; Espana R; Gambello MJ; Goines K; Klaiman C; Koh S; Russo RS
  • Attenuation of the Hepatoprotective Effects of Ileal Apical Sodium Dependent Bile Acid Transporter (ASBT) Inhibition in Choline-Deficient L-Amino Acid-Defined (CDAA) Diet-Fed Mice.
    Front Med (Lausanne) Volume: 7 Page(s): 60
    01/01/2020 Authors: Rao A; van de Peppel IP; Gumber S; Karpen SJ; Dawson PA
  • THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters.
    Br J Pharmacol Volume: 176 Suppl 1 Page(s): S397 - S493
    12/01/2019 Authors: Alexander SPH; Kelly E; Mathie A; Peters JA; Veale EL; Armstrong JF; Faccenda E; Harding SD; Pawson AJ; Sharman JL
  • METABOLIC DYSFUNCTION AS A CONTRIBUTOR TO PHENOTYPES OF THE SCHIZOPHRENIA-ASSOCIATED 3Q29 DELETION
    Volume: 29 Page(s): S224 - S225
    10/01/2019 Authors: Pollak R; Purcell R; Rutkowski T; Malone T; Pachura K; Bassell GJ; Epstein MP; Caspary T; Dawson PA; Jones DP
  • Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration.
    Cell Stem Cell Volume: 25 Page(s): 23 - 38.e8
    07/03/2019 Authors: Pepe-Mooney BJ; Dill MT; Alemany A; Ordovas-Montanes J; Matsushita Y; Rao A; Sen A; Miyazaki M; Anakk S; Dawson PA
  • Animal models to study bile acid metabolism.
    Biochim Biophys Acta Mol Basis Dis Volume: 1865 Page(s): 895 - 911
    05/01/2019 Authors: Li J; Dawson PA
  • PHARMACOLOGICAL INHIBITION OF THE APICAL SODIUM-DEPENDENT BILE ACID TRANSPORTER (ASBT) PROTECTS ILEAL ENTEROCYTES FROM BILE ACID-INDUCED INJURY IN ADULT ORGANIC ANION TRANSPORTER-ALPHA (OSTa) NULL MICE
    Volume: 156 Page(s): S66 - S66
    05/01/2019 Authors: Rao A; Pachura K; Karpen S; Dawson PA
  • Asbt Is Not Required for the Choleretic Actions of 24-Norursodeoxycholic Acid in Mice
    Volume: 68 Page(s): 31A - 31A
    10/01/2018 Authors: Li J; Rao A; Pachura K; Ferrebee C; Fuchs CD; Karpen SJ; Trauner MH; Dawson PA
  • Hepatic thyroid hormone receptor 1 agonism: good for lipids, good for bile?
    J Lipid Res Volume: 59 Page(s): 1551 - 1553
    09/01/2018 Authors: Dawson PA; Parini P
  • Organic solute transporter- (SLC51B) deficiency in two brothers with congenital diarrhea and features of cholestasis.
    Hepatology Volume: 68 Page(s): 590 - 598
    08/01/2018 Authors: Sultan M; Rao A; Elpeleg O; Vaz FM; Abu-Libdeh B; Karpen SJ; Dawson PA
  • Organic Solute Transporter - Protects Ileal Enterocytes From Bile Acid-Induced Injury.
    Cell Mol Gastroenterol Hepatol Volume: 5 Page(s): 499 - 522
    01/01/2018 Authors: Ferrebee CB; Li J; Haywood J; Pachura K; Robinson BS; Hinrichs BH; Jones RM; Rao A; Dawson PA
  • Hepatic bile acid uptake in humans and mice: Multiple pathways and expanding potential role for gut-liver signaling.
    Hepatology Volume: 66 Page(s): 1384 - 1386
    11/01/2017 Authors: Dawson PA
  • Early Anti-steatotic Actions of an Ileal Apical Sodium-dependent Bile Acid Transporter Inhibitor in High Fat Diet Fed Mice
    HEPATOLOGY Volume: 66 Page(s): 1049A - 1050A
    10/01/2017 Authors: Rao A; Zhang W; Xu T; Wynn GM; Wu H; Setchell KD; Karpen SJ; Dawson P
  • Will the real bile acid sulfotransferase please stand up? Identification of Sult2a8 as a major hepatic bile acid sulfonating enzyme in mice.
    J Lipid Res Volume: 58 Page(s): 1033 - 1035
    06/01/2017 Authors: Dawson PA; Setchell KDR
  • GATA4 Is Sufficient to Establish Jejunal Versus Ileal Identity in the Small Intestine.
    Cell Mol Gastroenterol Hepatol Volume: 3 Page(s): 422 - 446
    05/01/2017 Authors: Thompson CA; Wojta K; Pulakanti K; Rao S; Dawson P; Battle MA
  • Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives.
    Hepatology Volume: 65 Page(s): 350 - 362
    01/01/2017 Authors: Arab JP; Karpen SJ; Dawson PA; Arrese M; Trauner M
  • Roles of Ileal ASBT and OST-OST in Regulating Bile Acid Signaling.
    Volume: 35 Page(s): 261 - 266
    01/01/2017 Authors: Dawson PA
  • Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet-fed mice.
    Sci Transl Med Volume: 8 Page(s): 357ra122
    09/21/2016 Authors: Rao A; Kosters A; Mells JE; Zhang W; Setchell KDR; Amanso AM; Wynn GM; Xu T; Keller BT; Yin H
  • Inflammation-associated upregulation of the sulfated steroid transporter Slc10a6 in mouse liver and macrophage cell lines.
    Hepatol Res Volume: 46 Page(s): 794 - 803
    07/01/2016 Authors: Kosters A; Abebe DF; Felix JC; Dawson PA; Karpen SJ
  • Toxic bile and sclerosing cholangitis: Is there a role for pharmacological interruption of the bile acid enterohepatic circulation?
    Hepatology Volume: 63 Page(s): 363 - 364
    02/01/2016 Authors: Dawson PA
  • Formula Feeding Predisposes Gut to NSAID-Induced Small Intestinal Injury.
    Clin Exp Pharmacol Volume: 6
    01/01/2016 Authors: Schuck-Phan A; Phan T; Dawson PA; Dial EJ; Bell C; Liu Y; Rhoads JM; Lichtenberger LM
  • CHARACTERIZATION OF THE SECRETORY TRANSPORT OF DRUGS IN THE MOUSE SMALL INTESTINE USING USSING CHAMBER SYSTEM
    DRUG METABOLISM REVIEWS Volume: 47 Page(s): 48 - 48
    11/20/2015 Authors: Nakayama T; Maeda K; Fukizawa S; Kato Y; Dawson PA; Kusuhara H
  • Slc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids.
    Carcinogenesis Volume: 36 Page(s): 1193 - 1200
    10/01/2015 Authors: Raufman J-P; Dawson PA; Rao A; Drachenberg CB; Heath J; Shang AC; Hu S; Zhan M; Polli JE; Cheng K
  • The Na(+) -taurocholate cotransporting polypeptide knockout mouse: A new tool for study of bile acids and hepatitis B virus biology.
    Hepatology Volume: 62 Page(s): 19 - 21
    07/01/2015 Authors: Kosters A; Dawson PA
  • Intestinal transport and metabolism of bile acids.
    J Lipid Res Volume: 56 Page(s): 1085 - 1099
    06/01/2015 Authors: Dawson PA; Karpen SJ
  • Metabolic effects of intestinal absorption and enterohepatic cycling of bile acids.
    Acta Pharm Sin B Volume: 5 Page(s): 129 - 134
    03/01/2015 Authors: Ferrebee CB; Dawson PA
  • In vitro evidence that phosphatidylcholine protects against indomethacin/bile acid-induced injury to cells.
    Am J Physiol Gastrointest Liver Physiol Volume: 308 Page(s): G217 - G222
    02/01/2015 Authors: Dial EJ; Dawson PA; Lichtenberger LM
  • Not all (bile acids) who wander are lost: the first report of a patient with an isolated NTCP defect.
    Hepatology Volume: 61 Page(s): 24 - 27
    01/01/2015 Authors: Karpen SJ; Dawson PA
  • Impact of Inhibiting Ileal Apical versus Basolateral Bile Acid Transport on Cholesterol Metabolism and Atherosclerosis in Mice.
    Volume: 33 Page(s): 382 - 387
    01/01/2015 Authors: Dawson PA
  • Design and evaluation of a novel trifluorinated imaging agent for assessment of bile acid transport using fluorine magnetic resonance imaging.
    J Pharm Sci Volume: 103 Page(s): 3782 - 3792
    11/01/2014 Authors: Vivian D; Cheng K; Khurana S; Xu S; Dawson PA; Raufman J-P; Polli JE
  • In vivo performance of a novel fluorinated magnetic resonance imaging agent for functional analysis of bile acid transport.
    Mol Pharm Volume: 11 Page(s): 1575 - 1582
    05/05/2014 Authors: Vivian D; Cheng K; Khurana S; Xu S; Kriel EH; Dawson PA; Raufman J-P; Polli JE
  • Bile acids reach out to the spinal cord: new insights to the pathogenesis of itch and analgesia in cholestatic liver disease.
    Hepatology Volume: 59 Page(s): 1638 - 1641
    04/01/2014 Authors: Dawson PA; Karpen SJ
  • Intestine-specific deletion of SIRT1 in mice impairs DCoH2-HNF-1-FXR signaling and alters systemic bile acid homeostasis.
    Gastroenterology Volume: 146 Page(s): 1006 - 1016
    04/01/2014 Authors: Kazgan N; Metukuri MR; Purushotham A; Lu J; Rao A; Lee S; Pratt-Hyatt M; Lickteig A; Csanaky IL; Zhao Y
  • A modified grapefruit juice eliminates two compound classes as major mediators of the grapefruit juice-fexofenadine interaction: an in vitro-in vivo "connect".
    J Clin Pharmacol Volume: 53 Page(s): 982 - 990
    09/01/2013 Authors: Won CS; Lan T; Vandermolen KM; Dawson PA; Oberlies NH; Widmer WW; Scarlett YV; Paine MF
  • Inhibition of ileal apical but not basolateral bile acid transport reduces atherosclerosis in apoE/ mice.
    Atherosclerosis Volume: 229 Page(s): 374 - 380
    08/01/2013 Authors: Lan T; Haywood J; Dawson PA
  • Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.
    Atherosclerosis Volume: 229 Page(s): 155 - 160
    07/01/2013 Authors: Cox AJ; Ng MC-Y; Xu J; Langefeld CD; Koch KL; Dawson PA; Carr JJ; Freedman BI; Hsu F-C; Bowden DW
  • Novel regulator of enterohepatic bile acid signaling protects against hypercholesterolemia.
    Cell Metab Volume: 17 Page(s): 816 - 818
    06/04/2013 Authors: Dawson PA
  • Analysis of the Contribution of Mrp3 (Abcc3) to Intestinal Bile Acid Transport and the Adaptive Response in Organic Solute Transporter (OST)alpha Knockout Mice
    HEPATOLOGY Volume: 56 Page(s): 539A - 539A
    10/01/2012 Authors: Rao A; Lan T; Haywood J; Dawson P
  • Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism.
    J Hepatol Volume: 57 Page(s): 359 - 365
    08/01/2012 Authors: Lan T; Rao A; Haywood J; Kock ND; Dawson PA
  • Dietary fish oil increases fat absorption and fecal bile acid content without altering bile acid synthesis in 20-d-old weanling rats following massive ileocecal resection.
    Pediatr Res Volume: 72 Page(s): 38 - 42
    07/01/2012 Authors: Yang Q; Lan T; Chen Y; Dawson PA
  • Defects in gallbladder emptying and bile Acid homeostasis in mice with cystic fibrosis transmembrane conductance regulator deficiencies.
    Gastroenterology Volume: 142 Page(s): 1581 - 91.e6
    06/01/2012 Authors: Debray D; Rainteau D; Barbu V; Rouahi M; El Mourabit H; Lerondel S; Rey C; Humbert L; Wendum D; Cottart C-H
  • Functional characterization of genetic variants in the apical sodium-dependent bile acid transporter (ASBT; SLC10A2).
    J Gastroenterol Hepatol Volume: 26 Page(s): 1740 - 1748
    12/01/2011 Authors: Ho RH; Leake BF; Urquhart BL; Gregor JC; Dawson PA; Kim RB
  • Ezetimibe restores biliary cholesterol excretion in mice expressing Niemann-Pick C1-Like 1 only in liver.
    Biochim Biophys Acta Volume: 1811 Page(s): 549 - 555
    09/01/2011 Authors: Tang W; Jia L; Ma Y; Xie P; Haywood J; Dawson PA; Li J; Yu L
  • Molecular mechanisms of altered bile acid homeostasis in organic solute transporter-alpha knockout mice.
    Dig Dis Volume: 29 Page(s): 18 - 22
    01/01/2011 Authors: Lan T; Haywood J; Rao A; Dawson PA
  • Role of the intestinal bile acid transporters in bile acid and drug disposition.
    Page(s): 169 - 203
    01/01/2011 Authors: Dawson PA
  • INACTIVATION OF ORGANIC SOLUTE TRANSPORTER (OST)alpha ALTERS BILE ACID HOMEOSTASIS VIA THE FXR-FGF15 PATHWAY
    HEPATOLOGY Volume: 52 Page(s): 431A - 431A
    10/01/2010 Authors: Lan T; Haywood JH; Rao A; Dawson PA
  • Getting the mOST from OST: Role of organic solute transporter, OSTalpha-OSTbeta, in bile acid and steroid metabolism.
    Biochim Biophys Acta Volume: 1801 Page(s): 994 - 1004
    09/01/2010 Authors: Dawson PA; Hubbert ML; Rao A
  • Conditional Gata4 deletion in mice induces bile acid absorption in the proximal small intestine.
    Gut Volume: 59 Page(s): 888 - 895
    07/01/2010 Authors: Beuling E; Kerkhof IM; Nicksa GA; Giuffrida MJ; Haywood J; aan de Kerk DJ; Piaseckyj CM; Pu WT; Buchmiller TL; Dawson PA
  • Liver disease without flipping: new functions of ATP8B1, the protein affected in familial intrahepatic cholestasis type 1.
    Hepatology Volume: 51 Page(s): 1885 - 1887
    06/01/2010 Authors: Dawson PA
  • Interaction of macrolide antibiotics with intestinally expressed human and rat organic anion-transporting polypeptides.
    Drug Metab Dispos Volume: 37 Page(s): 2375 - 2382
    12/01/2009 Authors: Lan T; Rao A; Haywood J; Davis CB; Han C; Garver E; Dawson PA
  • Bile acid transporters.
    J Lipid Res Volume: 50 Page(s): 2340 - 2357
    12/01/2009 Authors: Dawson PA; Lan T; Rao A
  • Cholesterol feeding prevents hepatic accumulation of bile acids in cholic acid-fed farnesoid X receptor (FXR)-null mice: FXR-independent suppression of intestinal bile acid absorption.
    Drug Metab Dispos Volume: 37 Page(s): 338 - 344
    02/01/2009 Authors: Miyata M; Matsuda Y; Nomoto M; Takamatsu Y; Sato N; Hamatsu M; Dawson PA; Gonzalez FJ; Yamazoe Y
  • Involvement of intestinal uptake transporters in the absorption of azithromycin and clarithromycin in the rat.
    Drug Metab Dispos Volume: 36 Page(s): 2492 - 2498
    12/01/2008 Authors: Garver E; Hugger ED; Shearn SP; Rao A; Dawson PA; Davis CB; Han C
  • Inactivation of the ileal bile acid transporter reduces ileal fibroblast growth factor 15 expression and limits atherosclerosis in apolipoprotein E and LDL receptor null mice
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY Volume: 28 Page(s): E121 - E121
    06/01/2008 Authors: Haywood J; Rao A; Dawson P
  • The organic solute transporter alpha-beta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis.
    Proc Natl Acad Sci U S A Volume: 105 Page(s): 3891 - 3896
    03/11/2008 Authors: Rao A; Haywood J; Craddock AL; Belinsky MG; Kruh GD; Dawson PA
  • FXR agonists and FGF15 reduce fecal bile acid excretion in a mouse model of bile acid malabsorption.
    J Lipid Res Volume: 48 Page(s): 2693 - 2700
    12/01/2007 Authors: Jung D; Inagaki T; Gerard RD; Dawson PA; Kliewer SA; Mangelsdorf DJ; Moschetta A
  • The basolateral transporter Ost alpha-Ost beta is essential for intestinal bile acid absorption and homeostasis
    HEPATOLOGY Volume: 46 Page(s): 271A - 271A
    10/01/2007 Authors: Rao A; Haywood J; Craddock AL; Belinsky MG; Kruh GD; Dawson PA
  • Analysis of ileal sodium/bile acid cotransporter and related nuclear receptor genes in a family with multiple cases of idiopathic bile acid malabsorption.
    World J Gastroenterol Volume: 12 Page(s): 7710 - 7714
    12/21/2006 Authors: Montagnani M; Abrahamsson A; Glman C; Eggertsen G; Marschall H-U; Ravaioli E; Einarsson C; Dawson PA
  • Cloning and expression of SLC10A4, a putative organic anion transport protein.
    World J Gastroenterol Volume: 12 Page(s): 6797 - 6805
    11/14/2006 Authors: Splinter P-L; Lazaridis K-N; Dawson P-A; LaRusso N-F
  • c-Fos is a critical mediator of inflammatory-mediated repression of the apical sodium-dependent bile acid transporter.
    Gastroenterology Volume: 131 Page(s): 554 - 567
    08/01/2006 Authors: Neimark E; Chen F; Li X; Magid MS; Alasio TM; Frankenberg T; Sinha J; Dawson PA; Shneider BL
  • Transactivation of rat apical sodium-dependent bile acid transporter and increased bile acid transport by 1alpha,25-dihydroxyvitamin D3 via the vitamin D receptor.
    Mol Pharmacol Volume: 69 Page(s): 1913 - 1923
    06/01/2006 Authors: Chen X; Chen F; Liu S; Glaeser H; Dawson PA; Hofmann AF; Kim RB; Shneider BL; Pang KS
  • Regulation of the mouse organic solute transporter alpha-beta, Ostalpha-Ostbeta, by bile acids.
    Am J Physiol Gastrointest Liver Physiol Volume: 290 Page(s): G912 - G922
    05/01/2006 Authors: Frankenberg T; Rao A; Chen F; Haywood J; Shneider BL; Dawson PA
  • OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia.
    Hepatology Volume: 42 Page(s): 1270 - 1279
    12/01/2005 Authors: Ballatori N; Christian WV; Lee JY; Dawson PA; Soroka CJ; Boyer JL; Madejczyk MS; Li N
  • Transcriptional regulation of the mouse organic solute transporter alpha-beta, mOST alpha-OST beta by bile acids
    HEPATOLOGY Volume: 42 Page(s): 507A - 507A
    10/01/2005 Authors: Frankenber T; Chen F; Rao A; Shneider B; Dawson P
  • Analysis of the in vivo functions of Mrp3.
    Mol Pharmacol Volume: 68 Page(s): 160 - 168
    07/01/2005 Authors: Belinsky MG; Dawson PA; Shchaveleva I; Bain LJ; Wang R; Ling V; Chen Z-S; Grinberg A; Westphal H; Klein-Szanto A
  • The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter.
    J Biol Chem Volume: 280 Page(s): 6960 - 6968
    02/25/2005 Authors: Dawson PA; Hubbert M; Haywood J; Craddock AL; Zerangue N; Christian WV; Ballatori N
  • Molecular mechanisms of intestinal bile acid transport
    Volume: 141 Page(s): 122 - 129
    01/01/2005 Authors: Dawson PA; Craddock AL; Haywood JH; Hubbert ML; Ballatori N
  • In memoriam: David L. Williams 1946-2004.
    J Lipid Res Volume: 45 Page(s): 2388 - 2389
    12/01/2004 Authors: Shelness GS; Dawson PA
  • Multidrug resistance-associated protein 3 (MRP3) is not required for intestinal absorption of bile acids in mice.
    HEPATOLOGY Volume: 40 Page(s): 732A - 732A
    10/01/2004 Authors: Dawson PA; Haywood J; Craddock AL; Belinsky MG; Kruh GD
  • The heteromeric organic solute transporter (Ost) alpha and beta complex is an ileal basolateral bile acid transporter.
    HEPATOLOGY Volume: 40 Page(s): 271A - 271A
    10/01/2004 Authors: Dawson PA; Craddock AL; Haywood J; Hubbert M; Forest W; Ballatori N
  • Interstrain differences in deoxycholate production influence intestinal bile acid absorption in ileal bile acid transporter (SLC10A2) knockout mice.
    HEPATOLOGY Volume: 40 Page(s): 494A - 494A
    10/01/2004 Authors: Dawson PA; Haywood J; Craddock AL; Hylemon PB
  • Taurocholate transport by hepatic and intestinal bile acid transporters is independent of FIC1 overexpression in Madin-Darby canine kidney cells.
    J Gastroenterol Hepatol Volume: 19 Page(s): 819 - 825
    07/01/2004 Authors: Harris MJ; Kagawa T; Dawson PA; Arias IM
  • The sodium bile salt cotransport family SLC10.
    Pflugers Arch Volume: 447 Page(s): 566 - 570
    02/01/2004 Authors: Hagenbuch B; Dawson P
  • Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice.
    J Biol Chem Volume: 278 Page(s): 33920 - 33927
    09/05/2003 Authors: Dawson PA; Haywood J; Craddock AL; Wilson M; Tietjen M; Kluckman K; Maeda N; Parks JS
  • Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter.
    J Biol Chem Volume: 278 Page(s): 19909 - 19916
    05/30/2003 Authors: Chen F; Ma L; Dawson PA; Sinal CJ; Sehayek E; Gonzalez FJ; Breslow J; Ananthanarayanan M; Shneider BL
  • Increases in biliary cholesterol-to-bile acid ratio in pregnant hamsters fed low and high levels of cholesterol.
    Am J Physiol Gastrointest Liver Physiol Volume: 284 Page(s): G263 - G268
    02/01/2003 Authors: Yao L; Dawson PA; Woollett LA
  • Expression cloning of receptor ligand transporters.
    Volume: 364 Page(s): 322 - 339
    01/01/2003 Authors: Dawson PA; Craddock AL
  • The effect of FICI expression on taurocholate transport by BSEP and IBAT in transfected MDCKII cells.
    HEPATOLOGY Volume: 36 Page(s): 309A - 309A
    10/01/2002 Authors: Harris MJ; Kagawa T; Dawson PA; Arias IM
  • Dapsone-induced cholestasis and impairment of bile salt output in the rat.
    Biochem Pharmacol Volume: 63 Page(s): 1553 - 1563
    04/15/2002 Authors: Veggi LM; Crocenzi FA; Roma MG; Dawson PA; Pellegrino JM; Snchez Pozzi EJ; Mottino AD
  • Dapsone-induced cholestasis and impairment of bile salt output in the rat
    JOURNAL OF HEPATOLOGY Volume: 36 Page(s): 261 - 261
    04/01/2002 Authors: Veggi LM; Crocenzi FA; Roma MG; Dawson PA; Pellegrino JM; Pozzi EJS; Mottino AD
  • Increased expression of ileal apical sodium-dependent bile acid transporter in postpartum rats.
    Am J Physiol Gastrointest Liver Physiol Volume: 282 Page(s): G41 - G50
    01/01/2002 Authors: Mottino AD; Hoffman T; Dawson PA; Luquita MG; Monti JA; Snchez Pozzi EJ; Catania VA; Cao J; Vore M
  • Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.
    Clin Pharmacol Ther Volume: 71 Page(s): 11 - 20
    01/01/2002 Authors: Dresser GK; Bailey DG; Leake BF; Schwarz UI; Dawson PA; Freeman DJ; Kim RB
  • Analysis of the ileal bile acid transporter gene, SLC10A2, in subjects with familial hypertriglyceridemia.
    Arterioscler Thromb Vasc Biol Volume: 21 Page(s): 2039 - 2045
    12/01/2001 Authors: Love MW; Craddock AL; Angelin B; Brunzell JD; Duane WC; Dawson PA
  • Identification of a novel human cytokine gene in the interleukin gene cluster on chromosome 2q12-14.
    J Interferon Cytokine Res Volume: 21 Page(s): 899 - 904
    11/01/2001 Authors: Bensen JT; Dawson PA; Mychaleckyj JC; Bowden DW
  • Absence of dysfunctional ileal sodium-bile acid cotransporter gene mutations in patients with adult-onset idiopathic bile acid malabsorption.
    Scand J Gastroenterol Volume: 36 Page(s): 1077 - 1080
    10/01/2001 Authors: Montagnani M; Love MW; Rssel P; Dawson PA; Qvist P
  • Identification of a novel human cytokine gene in the interleukin gene cluster on chromosome 2q12-14.
    AMERICAN JOURNAL OF HUMAN GENETICS Volume: 69 Page(s): 358 - 358
    10/01/2001 Authors: Bensen JT; Dawson PA; Mychaleckyj JC; Bowden DW
  • Intestinal bile acid transport: New insights from mouse and human models
    Volume: 120 Page(s): 161 - 168
    01/01/2001 Authors: Dawson PA; Craddock AL; Haywood JH; Tietjen M
  • Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1.
    Mol Genet Metab Volume: 74 Page(s): 186 - 199
    01/01/2001 Authors: Dawson PA; Mychaleckyj JC; Fossey SC; Mihic SJ; Craddock AL; Bowden DW
  • Expression, transport properties, and chromosomal location of organic anion transporter subtype 3.
    Am J Physiol Gastrointest Liver Physiol Volume: 279 Page(s): G1188 - G1200
    12/01/2000 Authors: Walters HC; Craddock AL; Fusegawa H; Willingham MC; Dawson PA
  • GLUT 10: A novel glucose transporter in the Type 2 diabetes linked region of chromosome 20p12-13.1.
    AMERICAN JOURNAL OF HUMAN GENETICS Volume: 67 Page(s): 51 - 51
    10/01/2000 Authors: Dawson PA; Fossey SC; Mihic SJ; Craddock AL; Mychaleckyj J; Snyder JR; Bowden DW
  • Increased intestinal transport of taurocholate (TC) in post-partum rats.
    HEPATOLOGY Volume: 32 Page(s): 439A - 439A
    10/01/2000 Authors: Mottino AD; Hoffman T; Dawson PA; Luquita MG; Monti JA; Pozzi EJS; Catania VA; Vore M
  • Identification of a dysfunctional ileal bile acid transporter gene in a patient with pigment gallstones.
    HEPATOLOGY Volume: 32 Page(s): 434A - 434A
    10/01/2000 Authors: Dawson PA; Montagnani M; Fusegawa H; Clarke G; Carey MC
  • Alternative splicing of the rat sodium/bile acid transporter changes its cellular localization and transport properties.
    Proc Natl Acad Sci U S A Volume: 97 Page(s): 11092 - 11097
    09/26/2000 Authors: Lazaridis KN; Tietz P; Wu T; Kip S; Dawson PA; LaRusso NF
  • oatp3 is an apical pile acid transporter in rat small intestine.
    GASTROENTEROLOGY Volume: 118 Page(s): A933 - A933
    04/01/2000 Authors: Walters HC; Craddock AL; Fusegawa H; Willingham M; Dawson P
  • Influence of J series prostaglandins on apoptosis and tumorigenesis of breast cancer cells.
    Carcinogenesis Volume: 20 Page(s): 1905 - 1911
    10/01/1999 Authors: Clay CE; Namen AM; Atsumi G; Willingham MC; High KP; Kute TE; Trimboli AJ; Fonteh AN; Dawson PA; Chilton FH
  • Membrane insertion scanning of the human ileal sodium/bile acid co-transporter.
    Biochemistry Volume: 38 Page(s): 11379 - 11388
    08/31/1999 Authors: Halln S; Brndn M; Dawson PA; Sachs G
  • Intestinal cholesterol absorption.
    Curr Opin Lipidol Volume: 10 Page(s): 315 - 320
    08/01/1999 Authors: Dawson PA; Rudel LL
  • Adolf Windaus Prize Lecture - Intestinal bile acid transport: molecules, mechanisms, and malabsorption
    Volume: 108 Page(s): 1 - 28
    01/01/1999 Authors: Dawson PA
  • Bile acid uptake via the human apical sodium-bile acid cotransporter is electrogenic.
    J Biol Chem Volume: 273 Page(s): 34691 - 34695
    12/25/1998 Authors: Weinman SA; Carruth MW; Dawson PA
  • Identification of a novel rat ileal organic anion transporter.
    HEPATOLOGY Volume: 28 Page(s): 386A - 386A
    10/01/1998 Authors: Walters HC; Craddock AL; Dawson PA
  • New insights into bile acid transport.
    Curr Opin Lipidol Volume: 9 Page(s): 225 - 229
    06/01/1998 Authors: Love MW; Dawson PA
  • Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter.
    Am J Physiol Volume: 274 Page(s): G157 - G169
    01/01/1998 Authors: Craddock AL; Love MW; Daniel RW; Kirby LC; Walters HC; Wong MH; Dawson PA
  • Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter.
    Am J Physiol Gastrointest Liver Physiol Volume: 274 Page(s): G157 - G169
    01/01/1998 Authors: Craddock AL; Love MW; Daniel RW; Kirby LC; Walters HC; Wong MH; Dawson PA
  • Cloning and characterization of a novel peptidase from rat and human ileum.
    J Biol Chem Volume: 272 Page(s): 31006 - 31015
    12/05/1997 Authors: Shneider BL; Thevananther S; Moyer MS; Walters HC; Rinaldo P; Devarajan P; Sun AQ; Dawson PA; Ananthanarayanan M
  • Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter.
    J Clin Invest Volume: 100 Page(s): 2714 - 2721
    12/01/1997 Authors: Lazaridis KN; Pham L; Tietz P; Marinelli RA; deGroen PC; Levine S; Dawson PA; LaRusso NF
  • Induction of sodium-dependent bile acid transporter messenger RNA, protein, and activity in rat ileum by cholic acid.
    Gastroenterology Volume: 113 Page(s): 1599 - 1608
    11/01/1997 Authors: Stravitz RT; Sanyal AJ; Pandak WM; Vlahcevic ZR; Beets JW; Dawson PA
  • Reconstitution of bile acid transport in a heterologous cell by cotransfection of transporters for bile acid uptake and efflux.
    J Biol Chem Volume: 272 Page(s): 18290 - 18297
    07/18/1997 Authors: Sippel CJ; Dawson PA; Shen T; Perlmutter DH
  • Cloning of the rat and human mitochondrial branched chain aminotransferases (BCATm).
    Biochim Biophys Acta Volume: 1339 Page(s): 9 - 13
    04/25/1997 Authors: Bledsoe RK; Dawson PA; Hutson SM
  • Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2).
    J Clin Invest Volume: 99 Page(s): 1880 - 1887
    04/15/1997 Authors: Oelkers P; Kirby LC; Heubi JE; Dawson PA
  • Bile acid uptake via the human ileal bile acid transporter is electrogenic.
    GASTROENTEROLOGY Volume: 112 Page(s): A1414 - A1414
    04/01/1997 Authors: Weinman SA; Carruth MW; Craddock AL; Dawson PA
  • The molecular genetics of ileal bile acid transport
    Volume: 93 Page(s): 153 - 160
    01/01/1997 Authors: Dawson PA; Oelkers P
  • LY295427, a novel hypocholesterolemic agent, enhances [3H]25-hydroxycholesterol binding to liver cytosolic proteins.
    J Lipid Res Volume: 37 Page(s): 2586 - 2598
    12/01/1996 Authors: Bowling N; Matter WF; Gadski RA; McClure DB; Schreyer T; Dawson PA; Vlahos CJ
  • Comparative analysis of the ontogeny of a sodium-dependent bile acid transporter in rat kidney and ileum.
    Am J Physiol Volume: 271 Page(s): G377 - G385
    08/01/1996 Authors: Christie DM; Dawson PA; Thevananther S; Shneider BL
  • Localization of the ileal sodium-bile acid cotransporter gene (SLC10A2) to human chromosome 13q33.
    Genomics Volume: 33 Page(s): 538 - 540
    05/01/1996 Authors: Wong MH; Rao PN; Pettenati MJ; Dawson PA
  • Induction of ileal bile acid transporter mRNA and protein by intestinal bile acids.
    GASTROENTEROLOGY Volume: 110 Page(s): A1335 - A1335
    04/01/1996 Authors: Stravitz RT; Sanyal AJ; Vlahcevic ZR; Pandak WM; Redford K; Dawson PA
  • Reconstitution of carrier-mediated bile acid uptake and efflux in a heterologous cell using DNA-mediated gene transfer.
    GASTROENTEROLOGY Volume: 110 Page(s): A1329 - A1329
    04/01/1996 Authors: Sippel CJ; Dawson P; Perlmutter DH
  • Primary bile acid malabsorption caused by mutations in the ileal bile acid transporter gene
    GASTROENTEROLOGY Volume: 110 Page(s): A826 - A826
    04/01/1996 Authors: Oelkers P; Heubi JE; Dawson PA
  • Cloning and expression of the mammalian cytosolic branched chain aminotransferase isoenzyme.
    J Biol Chem Volume: 270 Page(s): 30344 - 30352
    12/22/1995 Authors: Hutson SM; Bledsoe RK; Hall TR; Dawson PA
  • Identification of a mutation in the ileal sodium-dependent bile acid transporter gene that abolishes transport activity.
    J Biol Chem Volume: 270 Page(s): 27228 - 27234
    11/10/1995 Authors: Wong MH; Oelkers P; Dawson PA
  • CHARACTERIZATION OF THE HUMAN ILEAL AND RENAL BILE-ACID TRANSPORTER IN TRANSFECTED COS AND CHO CELLS
    HEPATOLOGY Volume: 22 Page(s): 848 - 848
    10/01/1995 Authors: CRADDOCK AL; DANIEL R; LOVE M; DAWSON PA
  • IDENTIFICATION OF A DYSFUNCTIONAL MUTATION IN THE HUMAN ILEAL BILE-ACID TRANSPORTER GENE
    HEPATOLOGY Volume: 22 Page(s): 727 - 727
    10/01/1995 Authors: OELKERS P; WONG MH; DAWSON PA
  • Cloning and chromosomal localization of the human ileal lipid-binding protein.
    Biochim Biophys Acta Volume: 1257 Page(s): 199 - 202
    07/13/1995 Authors: Oelkers P; Dawson PA
  • Bile acid transporters.
    Curr Opin Lipidol Volume: 6 Page(s): 109 - 114
    04/01/1995 Authors: Dawson PA; Oelkers P
  • Cloning and molecular characterization of the ontogeny of a rat ileal sodium-dependent bile acid transporter.
    J Clin Invest Volume: 95 Page(s): 745 - 754
    02/01/1995 Authors: Shneider BL; Dawson PA; Christie DM; Hardikar W; Wong MH; Suchy FJ
  • The apical membrane bile acid transporter of the ileal enterocyte
    Volume: 80 Page(s): 197 - 204
    01/01/1995 Authors: Dawson PA; Wong MH
  • CLONING AND CHROMOSOMAL LOCALIZATION OF THE HUMAN ILEAL RENAL SODIUM-DEPENDENT BILE-ACID TRANSPORTER
    GASTROENTEROLOGY Volume: 106 Page(s): A1009 - A1009
    04/01/1994 Authors: WONG MH; PETTENATI M; RAO N; DAWSON PA
  • CLONING AND MOLECULAR CHARACTERIZATION OF THE ONTOGENY OF THE RAT ILEAL SODIUM-DEPENDENT BILE-ACID TRANSPORTER
    GASTROENTEROLOGY Volume: 106 Page(s): A633 - A633
    04/01/1994 Authors: SHNEIDER B; DAWSON P; CHRISTIE D; WONG M; SUCHY F
  • BRANCHED-CHAIN AMINOTRANSFERASE (BCAT) ISOENZYMES - CLONING AND INVESTIGATION OF THE PHYSIOLOGICAL-ROLE OF THE CYTOSOLIC ENZYME FROM RAT-BRAIN
    FASEB JOURNAL Volume: 8 Page(s): A545 - A545
    03/01/1994 Authors: HALL TR; DAWSON PA; BLEDSOE RK; HUTSON SM
  • Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter.
    J Biol Chem Volume: 269 Page(s): 1340 - 1347
    01/14/1994 Authors: Wong MH; Oelkers P; Craddock AL; Dawson PA
  • Translocation of oxysterol binding protein to Golgi apparatus triggered by ligand binding.
    J Cell Biol Volume: 116 Page(s): 307 - 319
    01/01/1992 Authors: Ridgway ND; Dawson PA; Ho YK; Brown MS; Goldstein JL
  • The primary structures of four subunits of the human, high-molecular-weight proteinase, macropain (proteasome), are distinct but homologous.
    Biochim Biophys Acta Volume: 1079 Page(s): 29 - 38
    08/09/1991 Authors: DeMartino GN; Orth K; McCullough ML; Lee LW; Munn TZ; Moomaw CR; Dawson PA; Slaughter CA
  • A 25-hydroxycholesterol-resistant cell line deficient in acyl-CoA: cholesterol acyltransferase.
    J Biol Chem Volume: 266 Page(s): 12734 - 12740
    07/05/1991 Authors: Metherall JE; Ridgway ND; Dawson PA; Goldstein JL; Brown MS
  • Genetic distinction between sterol-mediated transcriptional and posttranscriptional control of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    J Biol Chem Volume: 266 Page(s): 9128 - 9134
    05/15/1991 Authors: Dawson PA; Metherall JE; Ridgway ND; Brown MS; Goldstein JL
  • cDNA cloning of human oxysterol-binding protein and localization of the gene to human chromosome 11 and mouse chromosome 19.
    Genomics Volume: 7 Page(s): 65 - 74
    05/01/1990 Authors: Levanon D; Hsieh CL; Francke U; Dawson PA; Ridgway ND; Brown MS; Goldstein JL
  • cDNA cloning and expression of oxysterol-binding protein, an oligomer with a potential leucine zipper.
    J Biol Chem Volume: 264 Page(s): 16798 - 16803
    10/05/1989 Authors: Dawson PA; Ridgway ND; Slaughter CA; Brown MS; Goldstein JL
  • Purification of oxysterol binding protein from hamster liver cytosol.
    J Biol Chem Volume: 264 Page(s): 9046 - 9052
    05/25/1989 Authors: Dawson PA; Van der Westhuyzen DR; Goldstein JL; Brown MS
  • Quantification and regulation of apolipoprotein E expression in rat Kupffer cells.
    J Lipid Res Volume: 30 Page(s): 403 - 413
    03/01/1989 Authors: Dawson PA; Lukaszewski LM; Ells PF; Malbon CC; Williams DL
  • REGULATION OF APO-E IN RAT ADRENAL-GLAND
    ARTERIOSCLEROSIS Volume: 8 Page(s): A563 - A563
    09/01/1988 Authors: WILLIAMS DL; DAWSON PA; MAHAFEE D; GWYNNE J
  • Sterol-dependent repression of low density lipoprotein receptor promoter mediated by 16-base pair sequence adjacent to binding site for transcription factor Sp1.
    J Biol Chem Volume: 263 Page(s): 3372 - 3379
    03/05/1988 Authors: Dawson PA; Hofmann SL; van der Westhuyzen DR; Sdhof TC; Brown MS; Goldstein JL
  • Structure, evolution, and regulation of chicken apolipoprotein A-I.
    J Biol Chem Volume: 262 Page(s): 7058 - 7065
    05/25/1987 Authors: Rajavashisth TB; Dawson PA; Williams DL; Shackleford JE; Lebherz H; Lusis AJ
  • Induction of rat E and chicken A-I apolipoproteins and mRNAs during optic nerve degeneration.
    J Biol Chem Volume: 261 Page(s): 5681 - 5684
    05/05/1986 Authors: Dawson PA; Schechter N; Williams DL
  • Immunochemical measurement of apolipoprotein synthesis in cell and organ culture.
    Methods Enzymol Volume: 129 Page(s): 254 - 271
    01/01/1986 Authors: Williams DL; Dawson PA
  • Quantitation of apolipoprotein E mRNA in the liver and peripheral tissues of nonhuman primates.
    J Biol Chem Volume: 260 Page(s): 2452 - 2457
    02/25/1985 Authors: Newman TC; Dawson PA; Rudel LL; Williams DL
  • Apolipoprotein E synthesis in peripheral tissues of nonhuman primates.
    J Biol Chem Volume: 260 Page(s): 2444 - 2451
    02/25/1985 Authors: Williams DL; Dawson PA; Newman TC; Rudel LL
  • REGULATION OF APO-E MESSENGER-RNA IN RAT KUPFFER CELLS
    ARTERIOSCLEROSIS Volume: 5 Page(s): A504 - A504
    01/01/1985 Authors: DAWSON PA; LUKASZEWSKI L; ELLS PF; MALBON CC; WILLIAMS DL
  • REGULATION OF APO-E MESSENGER-RNA IN RAT KUPFFER CELLS
    Volume: 72 Page(s): 143 - 143
    01/01/1985 Authors: DAWSON PA; LUKASZEWSKI L; ELLS PF; MALBON CC; WILLIAMS DL
  • Synthesis of apolipoprotein E by peripheral tissues. Potential functions in reverse cholesterol transport and cellular cholesterol metabolism.
    Ann N Y Acad Sci Volume: 454 Page(s): 222 - 229
    01/01/1985 Authors: Williams DL; Dawson PA; Newman TC; Rudel LL
  • APO-E MESSENGER-RNA IN PERIPHERAL-TISSUES OF MACACA FASCICULARIS
    Volume: 70 Page(s): 120 - 120
    01/01/1984 Authors: NEWMAN TC; DAWSON PA; RUDEL LL; WILLIAMS DL
  • APOLIPOPROTEIN E SYNTHESIS BY ISOLATED RAT KUPFFER CELLS
    ARTERIOSCLEROSIS Volume: 4 Page(s): A519 - A520
    01/01/1984 Authors: DAWSON PA; LUKASZEWSKI L; ELLS PF; MALBON CC; WILLIAMS DL
  • APO-E MESSENGER-RNA IN PERIPHERAL-TISSUES OF MACACA FASCICULARIS
    ARTERIOSCLEROSIS Volume: 4 Page(s): A522 - A522
    01/01/1984 Authors: NEWMAN TC; DAWSON PA; RUDEL LL; WILLIAMS DL
  • SYNTHESIS OF APO-A-I AND APO-E IN NON-HUMAN PRIMATE PERIPHERAL-TISSUES
    ARTERIOSCLEROSIS Volume: 3 Page(s): A508 - A508
    01/01/1983 Authors: WILLIAMS DL; DAWSON PA; RUDEL LL
  • APOLIPOPROTEIN-B SYNTHESIS BY THE LIVER AND INTESTINE OF THE AFRICAN-GREEN MONKEY
    ARTERIOSCLEROSIS Volume: 3 Page(s): A508 - A508
    01/01/1983 Authors: WILLIAMS DL; DAWSON PA; RUDEL LL
Read more publications Fewer publications
Directory
  • Faculty Profiles
Emory University Homepage

Contact & Location

Emory University School of Medicine
100 Woodruff Circle
Atlanta, GA  30322 USA
  • Contact Us
  • Maps & Directions
  • Careers

Information For

  • Alumni
  • Faculty & Staff
  • Patients
  • Residents & Fellows
  • Students
Support the School of Medicine School of Medicine Intranet
facebook facebook twitter twitter linkedin linkedin instagram instagram youtube youtube
© 2025 Emory University
  • Privacy Policy
  • Emergency Information
  • EEO Employer-Disability/Veteran Statements