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Profile

Nick Willett PhD

  • Department of Orthopaedics
    Associate Professor
  • nick.willett@emory.edu
Head shot of Nick Willett

Academic Appointment

  • Assistant Professor, Emory University

Education

Degrees

  • PhD from Georgia Institute of Technology

Research

Publications

  • Injury-associated anemia and iron homeostasis following orthopaedic trauma: a prospective observational study of 844 patients.
    J Orthop Trauma
    06/09/2025 Authors: Peterson DF; McKibben NS; Duke VR; Hutchison CE; Yang CJ; Curtis C; Lancaster K; Trapalis T; Choi D; Shatzel JJ
  • CYR61 delivery promotes angiogenesis during bone fracture repair.
    NPJ Regen Med Volume: 10 Page(s): 20
    04/22/2025 Authors: Lang A; Eastburn EA; Younesi M; Nijsure MP; Siciliano C; Pranatharthi Haran A; Panebianco CJ; Seidl E; Tang R; Alsberg E
  • FTY720P-treated macrophages in PEG-4MAL hydrogels promote oral wound healing.
    Cytotherapy Volume: 27 Page(s): 338 - 349
    03/01/2025 Authors: Burnham AJ; Toma AI; Shah D; Cha T; Kaimari S; Behara M; Sekar KPC; Kamalakar A; Willett N; Botchwey E
  • Osteoarthritis early-, mid- and late-stage progression in the rat medial meniscus transection model.
    J Orthop Res Volume: 43 Page(s): 102 - 116
    01/01/2025 Authors: McKinney JM; Pucha KA; Bernard FC; Brandon Dixon J; Doan TN; Willett NJ
  • Early resistance rehabilitation improves functional regeneration following segmental bone defect injury.
    NPJ Regen Med Volume: 9 Page(s): 38
    12/12/2024 Authors: Williams KE; Harrer JA; LaBelle SA; Leguineche K; Kaiser J; Karipott S; Lin A; Vongphachanh A; Fulton T; Walker Rosenthal J
  • Accelerating Oral Wound Healing Using Bilayer Biomaterial Delivery of FTY720 Immunotherapy.
    Adv Healthc Mater Volume: 13 Page(s): e2401480
    12/01/2024 Authors: Toma AI; Shah D; Roth D; Pia JO; Hymel L; Turner T; Kamalakar A; Liu K; Bartsch P; Jacobs L
  • Age-associated functional healing of musculoskeletal trauma through regenerative engineering and rehabilitation.
    Biomater Sci Volume: 12 Page(s): 5186 - 5202
    10/08/2024 Authors: Habing KM; Alcazar CA; Duke VR; Tan YH; Willett NJ; Nakayama KH
  • Local FK506 delivery induces osteogenesis in rat bone defect and rabbit spine fusion models.
    Bone Volume: 187 Page(s): 117195
    10/01/2024 Authors: Andraca Harrer J; Fulton TM; Sangadala S; Kaiser JM; Devereaux EJ; Oliver C; Presciutti SM; Boden SD; Willett NJ
  • Mild exercise expedites joint clearance and slows joint degradation in a joint instability model of osteoarthritis in male rats.
    Osteoarthritis Cartilage Volume: 32 Page(s): 912 - 921
    07/01/2024 Authors: Kaiser JM; Bernard FC; Pucha K; Raval SK; Eng T; Fulton T; Anderson SE; Allen KD; Dixon JB; Willett NJ
  • Cyr61 delivery promotes angiogenesis during bone fracture repair.
    bioRxiv
    04/06/2024 Authors: Lang A; Eastburn EA; Younesi M; Nijsure M; Siciliano C; Haran AP; Panebianco CJ; Seidl E; Tang R; Alsberg E
  • Local FK506 delivery induces osteogenesis in in vivo rat bone defect and rabbit spine fusion models.
    bioRxiv
    03/13/2024 Authors: Harrer JA; Fulton TM; Sangadala S; Kaiser J; Devereaux EJ; Oliver C; Presciutti SM; Boden SD; Willett NJ
  • Harnessing Bilayer Biomaterial Delivery of FTY720 as an Immunotherapy to Accelerate Oral Wound Healing.
    bioRxiv
    12/23/2023 Authors: Toma AI; Shah D; Roth D; Oliver Pia J; Hymel L; Turner T; Kamalakar A; Liu K; Bartsch P; Jacobs L
  • Leveraging 3D Bioprinting and Photon-Counting Computed Tomography to Enable Noninvasive Quantitative Tracking of Multifunctional Tissue Engineered Constructs.
    Adv Healthc Mater Volume: 12 Page(s): e2302271
    12/01/2023 Authors: Gil CJ; Evans CJ; Li L; Allphin AJ; Tomov ML; Jin L; Vargas M; Hwang B; Wang J; Putaturo V
  • Early Resistance Rehabilitation Improves Functional Regeneration Following Segmental Bone Defect Injury.
    Res Sq
    10/04/2023 Authors: Williams KE; Andraca Harrer J; LaBelle SA; Leguineche K; Kaiser J; Karipott S; Lin A; Vongphachanh A; Fulton T; Rosenthal JW
  • Identifying dysregulated immune cell subsets following volumetric muscle loss with pseudo-time trajectories.
    Commun Biol Volume: 6 Page(s): 749
    07/19/2023 Authors: Hymel LA; Anderson SE; Turner TC; York WY; Zhang H; Liversage AR; Lim HS; Qiu P; Mortensen LJ; Jang YC
  • Lentiviral overexpression of VEGFC in transplanted MSCs leads to resolution of swelling in a mouse tail lymphedema model.
    Microcirculation Volume: 30 Page(s): e12792
    04/01/2023 Authors: Michalaki E; Rudd JM; Liebman L; Wadhwani R; Wood LB; Willett NJ; Dixon JB
  • Role of single-dose intravenous iron therapy for the treatment of anaemia after orthopaedic trauma: protocol for a pilot randomised controlled trial.
    BMJ Open Volume: 13 Page(s): e069070
    03/21/2023 Authors: Peterson DF; McKibben NS; Hutchison CE; Lancaster K; Yang CJ; Dekeyser GJ; Friess DM; Schreiber MA; Willett NJ; Shatzel JJ
  • Intra-articular delivery of micronized dehydrated human amnion/chorion membrane reduces degenerative changes after onset of post-traumatic osteoarthritis.
    Front Bioeng Biotechnol Volume: 11 Page(s): 1224141
    01/01/2023 Authors: Lin ASP; Reece DS; Thote T; Sridaran S; Stevens HY; Willett NJ; Guldberg RE
  • Modulating Rehabilitation Intensity To Improve Functional Regeneration Of Severe Bone Fractures
    Volume: 28 Page(s): 90 - 91
    08/01/2022 Authors: Nash KE; Harrer J; Leguineche K; Lin AS; Klosterhoff B; Willett N; Guldberg RE
  • Effect of Human Synovial Fluid From Osteoarthritis Patients and Healthy Individuals on Lymphatic Contractile Activity.
    J Biomech Eng Volume: 144
    07/01/2022 Authors: Michalaki E; Nepiyushchikh Z; Rudd JM; Bernard FC; Mukherjee A; McKinney JM; Doan TN; Willett NJ; Dixon JB
  • Neutrophil and natural killer cell imbalances prevent muscle stem cell-mediated regeneration following murine volumetric muscle loss.
    Proc Natl Acad Sci U S A Volume: 119 Page(s): e2111445119
    04/12/2022 Authors: Larouche JA; Fraczek PM; Kurpiers SJ; Yang BA; Davis C; Castor-Macias JA; Sabin K; Anderson S; Harrer J; Hall M
  • NSAIDs Reduce Therapeutic Efficacy of Mesenchymal Stromal Cell Therapy in a Rodent Model of Posttraumatic Osteoarthritis.
    Am J Sports Med Volume: 50 Page(s): 1389 - 1398
    04/01/2022 Authors: Sok D; Raval S; McKinney J; Drissi H; Mason A; Mautner K; Kaiser JM; Willett NJ
  • MILD EXERCISE AND MESENCHYMAL STROMAL CELL INJECTIONS ALLEVIATE POST-TRAUMATIC OSTEOARTHRITIS
    Volume: 28 Page(s): S445 - S445
    04/01/2022 Authors: Kaiser J; McKinney J; Bernard F; Pucha K; Raval S; Sok D; Fulton T; Anderson S; Dixon B; Willett N
  • HARNESSING IMMUNE CELL PSEUDOTIME TRAJECTORY ANALYSIS TO INFORM REGENERATIVE MEDICINE STRATEGIES IN CRITICALLY SIZED VOLUMETRIC MUSCLE LOSS INJURY
    Volume: 28 Page(s): S568 - S569
    04/01/2022 Authors: Hymel LA; Anderson SE; Ogle ME; Turner TC; York WY; Lim HS; Jang YC; Willett NJ; Botchwey EA
  • Sodium alginate microencapsulation of human mesenchymal stromal cells modulates paracrine signaling response and enhances efficacy for treatment of established osteoarthritis.
    Acta Biomater Volume: 141 Page(s): 315 - 332
    03/15/2022 Authors: McKinney JM; Pucha KA; Doan TN; Wang L; Weinstock LD; Tignor BT; Fowle KL; Levit RD; Wood LB; Willett NJ
  • Effects of osteogenic ambulatory mechanical stimulation on early stages of BMP-2 mediated bone repair.
    Connect Tissue Res Volume: 63 Page(s): 16 - 27
    01/01/2022 Authors: Klosterhoff BS; Vantucci CE; Kaiser J; Ong KG; Wood LB; Weiss JA; Guldberg RE; Willett NJ
  • Systemic Immune Modulation Alters Local Bone Regeneration in a Delayed Treatment Composite Model of Non-Union Extremity Trauma.
    Front Surg Volume: 9 Page(s): 934773
    01/01/2022 Authors: Vantucci CE; Guyer T; Leguineche K; Chatterjee P; Lin A; Nash KE; Hastings MA; Fulton T; Smith CT; Maniar D
  • Multichromatic near-infrared imaging to assess interstitial lymphatic and venous uptake in vivo.
    J Biomed Opt Volume: 26
    12/01/2021 Authors: Bernard FC; Kaiser J; Raval SK; Nepiyushchikh ZV; Doan TN; Willett NJ; Dixon JB
  • Oral wound healing models and emerging regenerative therapies.
    Transl Res Volume: 236 Page(s): 17 - 34
    10/01/2021 Authors: Toma AI; Fuller JM; Willett NJ; Goudy SL
  • Triple growth factor delivery promotes functional bone regeneration following composite musculoskeletal trauma.
    Acta Biomater Volume: 127 Page(s): 180 - 192
    06/01/2021 Authors: Subbiah R; Ruehle MA; Klosterhoff BS; Lin ASP; Hettiaratchi MH; Willett NJ; Bertassoni LE; Garca AJ; Guldberg RE
  • Modulating local S1P receptor signaling as a regenerative immunotherapy after volumetric muscle loss injury.
    J Biomed Mater Res A Volume: 109 Page(s): 695 - 712
    05/01/2021 Authors: Hymel LA; Ogle ME; Anderson SE; San Emeterio CL; Turner TC; York WY; Liu AY; Olingy CE; Sridhar S; Lim HS
  • 3D Bioprinted Bacteriostatic Hyperelastic Bone Scaffold for Damage-Specific Bone Regeneration.
    Polymers (Basel) Volume: 13
    03/30/2021 Authors: Shokouhimehr M; Theus AS; Kamalakar A; Ning L; Cao C; Tomov ML; Kaiser JM; Goudy S; Willett NJ; Jang HW
  • JAGGED1 stimulates cranial neural crest cell osteoblast commitment pathways and bone regeneration independent of canonical NOTCH signaling.
    Bone Volume: 143 Page(s): 115657
    02/01/2021 Authors: Kamalakar A; McKinney JM; Salinas Duron D; Amanso AM; Ballestas SA; Drissi H; Willett NJ; Bhattaram P; Garca AJ; Wood LB
  • Bifunctional Janus Particles as Multivalent Synthetic Nanoparticle Antibodies (SNAbs) for Selective Depletion of Target Cells.
    Nano Lett Volume: 21 Page(s): 875 - 886
    01/13/2021 Authors: Liu J; Toy R; Vantucci C; Pradhan P; Zhang Z; Kuo KM; Kubelick KP; Huo D; Wen J; Kim J
  • Local delivery of FTY720 induces neutrophil activation through chemokine signaling in an oronasal fistula model.
    Regen Eng Transl Med Volume: 7 Page(s): 160 - 174
    01/01/2021 Authors: Amanso AM; Turner TC; Kamalakar A; Ballestas SA; Hymel LA; Randall J; Johnston R; Arthur RA; Willett NJ; Botchwey EA
  • Nanofiber-Based Delivery of Bioactive Lipids Promotes Pro-regenerative Inflammation and Enhances Muscle Fiber Growth After Volumetric Muscle Loss.
    Front Bioeng Biotechnol Volume: 9 Page(s): 650289
    01/01/2021 Authors: San Emeterio CL; Hymel LA; Turner TC; Ogle ME; Pendleton EG; York WY; Olingy CE; Liu AY; Lim HS; Sulchek TA
  • Development of systemic immune dysregulation in a rat trauma model of biomaterial-associated infection.
    Biomaterials Volume: 264 Page(s): 120405
    01/01/2021 Authors: Vantucci CE; Ahn H; Fulton T; Schenker ML; Pradhan P; Wood LB; Guldberg RE; Roy K; Willett NJ
  • Characterization of OA development between sexes in the rat medial meniscal transection model.
    Osteoarthr Cartil Open Volume: 2 Page(s): 100066
    09/01/2020 Authors: Pucha KA; McKinney JM; Fuller JM; Willett NJ
  • Correction: Sangadala, S. et al. FK506 Induces Ligand-Independent Activation of the Bone Morphogenetic Protein Pathway and Osteogenesis. Int. J. Mol. Sci. 2019, 20, 1900.
    Int J Mol Sci Volume: 21
    08/31/2020 Authors: Sangadala S; Devereaux EJ; Presciutti SM; Boden SD; Willett NJ
  • Extracellular matrix compression temporally regulates microvascular angiogenesis.
    Sci Adv Volume: 6
    08/01/2020 Authors: Ruehle MA; Eastburn EA; LaBelle SA; Krishnan L; Weiss JA; Boerckel JD; Wood LB; Guldberg RE; Willett NJ
  • Biocompatible liquid-crystal elastomers mimic the intervertebral disc.
    J Mech Behav Biomed Mater Volume: 107 Page(s): 103757
    07/01/2020 Authors: Shaha RK; Merkel DR; Anderson MP; Devereaux EJ; Patel RR; Torbati AH; Willett N; Yakacki CM; Frick CP
  • Wireless sensor enables longitudinal monitoring of regenerative niche mechanics during rehabilitation that enhance bone repair.
    Bone Volume: 135 Page(s): 115311
    06/01/2020 Authors: Klosterhoff BS; Kaiser J; Nelson BD; Karipott SS; Ruehle MA; Hollister SJ; Weiss JA; Ong KG; Willett NJ; Guldberg RE
  • Taking the Next Steps in Regenerative Rehabilitation: Establishment of a New Interdisciplinary Field.
    Arch Phys Med Rehabil Volume: 101 Page(s): 917 - 923
    05/01/2020 Authors: Willett NJ; Boninger ML; Miller LJ; Alvarez L; Aoyama T; Bedoni M; Brix KA; Chisari C; Christ G; Dearth CL
  • Development of a Small Animal Ankle Arthrodesis Model.
    Foot Ankle Int Volume: 41 Page(s): 101 - 108
    01/01/2020 Authors: Kadakia RJ; Devereaux EJ; Ahn H; Traub BC; Kephart D; Willett NJ; Bariteau JT
  • Reduced Size Profile of Amniotic Membrane Particles Decreases Osteoarthritis Therapeutic Efficacy.
    Tissue Eng Part A Volume: 26 Page(s): 28 - 37
    01/01/2020 Authors: Reece DS; Burnsed OA; Parchinski K; Marr EE; White RM; Salazar-Noratto GE; Lin ASP; Willett NJ; Guldberg RE
  • Harnessing the Osteo-inductive Property of JAGGED1 as a Maxillary Bone Regenerative Intervention
    Volume: 34 Page(s): 221 - 221
    12/01/2019 Authors: Kamalakar A; Amanso A; Ballestas S; Willett N; Drissi H; Goudy S; Davis M
  • Harnessing the Osteo-inductive Property of JAGGED1 as a Maxillary Bone Regenerative Intervention
    Volume: 34 Page(s): 221 - 221
    12/01/2019 Authors: Kamalakar A; Amanso A; Ballestas S; Willett N; Drissi H; Goudy S; Davis M
  • Effects of treadmill running and limb immobilization on knee cartilage degeneration and locomotor joint kinematics in rats following knee meniscal transection.
    Osteoarthritis Cartilage Volume: 27 Page(s): 1851 - 1859
    12/01/2019 Authors: Tsai L-C; Cooper ES; Hetzendorfer KM; Warren GL; Chang Y-H; Willett NJ
  • Endothelin-1 inhibits size dependent lymphatic clearance of PEG-based conjugates after intra-articular injection into the rat knee.
    Acta Biomater Volume: 93 Page(s): 270 - 281
    07/15/2019 Authors: Doan TN; Bernard FC; McKinney JM; Dixon JB; Willett NJ
  • Decorin-supplemented collagen hydrogels for the co-delivery of bone morphogenetic protein-2 and microvascular fragments to a composite bone-muscle injury model with impaired vascularization.
    Acta Biomater Volume: 93 Page(s): 210 - 221
    07/15/2019 Authors: Ruehle MA; Li M-TA; Cheng A; Krishnan L; Willett NJ; Guldberg RE
  • Improving hard palate wound healing using immune modulatory autotherapies.
    Acta Biomater Volume: 91 Page(s): 209 - 219
    06/01/2019 Authors: Ballestas SA; Turner TC; Kamalakar A; Stephenson YC; Willett NJ; Goudy SL; Botchwey EA
  • Mir-155 is a Negative Regulator of Acute Oscillatory Shear Stress-induced AT1R/ETS-1 Pathway and Downstream Vascular Inflammation and Barrier Dysfunction
    Volume: 39
    05/01/2019 Authors: Mohamed I; Thomas S; Rooney K; Willett N; Taylor WR; Searles C
  • FK506 Induces Ligand-Independent Activation of the Bone Morphogenetic Protein Pathway and Osteogenesis.
    Int J Mol Sci Volume: 20
    04/17/2019 Authors: Sangadala S; Devereaux EJ; Presciutti SM; Boden SD; Willet NJ
  • Effects of BMP-2 dose and delivery of microvascular fragments on healing of bone defects with concomitant volumetric muscle loss.
    J Orthop Res Volume: 37 Page(s): 553 - 561
    03/01/2019 Authors: Ruehle MA; Krishnan L; Vantucci CE; Wang Y; Stevens HY; Roy K; Guldberg RE; Willett NJ
  • Determination of a Critical Size Threshold for Volumetric Muscle Loss in the Mouse Quadriceps.
    Tissue Eng Part C Methods Volume: 25 Page(s): 59 - 70
    02/01/2019 Authors: Anderson SE; Han WM; Srinivasa V; Mohiuddin M; Ruehle MA; Moon JY; Shin E; San Emeterio CL; Ogle ME; Botchwey EA
  • A non-canonical JAGGED1 signal to JAK2 mediates osteoblast commitment in cranial neural crest cells.
    Cell Signal Volume: 54 Page(s): 130 - 138
    02/01/2019 Authors: Kamalakar A; Oh MS; Stephenson YC; Ballestas-Naissir SA; Davis ME; Willett NJ; Drissi HM; Goudy SL
  • Therapeutic efficacy of intra-articular delivery of encapsulated human mesenchymal stem cells on early stage osteoarthritis.
    Eur Cell Mater Volume: 37 Page(s): 42 - 59
    01/29/2019 Authors: McKinney JM; Doan TN; Wang L; Deppen J; Reece DS; Pucha KA; Ginn S; Levit RD; Willett NJ
  • Correction for Sago et al., High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing.
    Proc Natl Acad Sci U S A Volume: 115 Page(s): E11427
    11/27/2018
  • High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing.
    Proc Natl Acad Sci U S A Volume: 115 Page(s): E9944 - E9952
    10/16/2018 Authors: Sago CD; Lokugamage MP; Paunovska K; Vanover DA; Monaco CM; Shah NN; Gamboa Castro M; Anderson SE; Rudoltz TG; Lando GN
  • Impact of Vancomycin Treatment on Human Mesenchymal Stromal Cells During Osteogenic Differentiation.
    Foot Ankle Int Volume: 39 Page(s): 954 - 959
    08/01/2018 Authors: Bariteau JT; Kadakia RJ; Traub BC; Viggeswarapu M; Willett NJ
  • Localized SDF-1 Delivery Increases Pro-Healing Bone Marrow-Derived Cells in the Supraspinatus Muscle Following Severe Rotator Cuff Injury.
    Regen Eng Transl Med Volume: 4 Page(s): 92 - 103
    06/01/2018 Authors: Tellier LE; Krieger JR; Brimeyer AL; Coogan AC; Falis AA; Rinker TE; Schudel A; Thomas SN; Jarrett CD; Willett NJ
  • Biological evaluation and finite-element modeling of porous poly(para-phenylene) for orthopaedic implants.
    Acta Biomater Volume: 72 Page(s): 352 - 361
    05/01/2018 Authors: Ahn H; Patel RR; Hoyt AJ; Lin ASP; Torstrick FB; Guldberg RE; Frick CP; Carpenter RD; Yakacki CM; Willett NJ
  • Intra-articular TSG-6 delivery from heparin-based microparticles reduces cartilage damage in a rat model of osteoarthritis.
    Biomater Sci Volume: 6 Page(s): 1159 - 1167
    05/01/2018 Authors: Tellier LE; Trevio EA; Brimeyer AL; Reece DS; Willett NJ; Guldberg RE; Temenoff JS
  • REGION-SPECIFIC KNEE CARTILAGE DEGRADATION ASSOCIATES WITH ALTERED KINEMATICS IN EXERCISE AND IMMOBILIZED OSTEOARTHRITIS RATS
    Volume: 26 Page(s): S361 - S362
    04/01/2018 Authors: Cooper ES; Tsai L-C; Hetzendorfer KM; Chang Y-H; Willett NJ
  • Contrast enhanced CT imaging of early articular changes in a pre-clinical model of osteoarthritis.
    Osteoarthritis Cartilage Volume: 26 Page(s): 118 - 127
    01/01/2018 Authors: Reece DS; Thote T; Lin ASP; Willett NJ; Guldberg RE
  • Development of Biological and Mechanical Evaluation of Porous poly(para-phenylene) for orthopedic implants
    Volume: 23 Page(s): S92 - S92
    12/01/2017 Authors: Ahn H; Patel R; Hoyt AJ; Lin AS; Torstrick B; Guldberg RE; Frick CP; Carpenter RD; Yakacki CM; Willett NJ
  • Immune-Dysregulation in a Rat Model of Infected Femoral Segmental Bone Defect
    Volume: 23 Page(s): S104 - S104
    12/01/2017 Authors: Ahn H; Schenker ML; Kadakia RJ; Pradhan P; Weinstock LD; Wood LB; Roy K; Guldberg RE; Willett NJ
  • Wireless Implantable Sensor for Noninvasive, Longitudinal Quantification of Axial Strain Across Rodent Long Bone Defects.
    J Biomech Eng Volume: 139 Page(s): 1110041 - 1110048
    11/01/2017 Authors: Klosterhoff BS; Ghee Ong K; Krishnan L; Hetzendorfer KM; Chang Y-H; Allen MG; Guldberg RE; Willett NJ
  • A Novel Technique for Accelerated Culture of Murine Mesenchymal Stem Cells that Allows for Sustained Multipotency.
    Sci Rep Volume: 7 Page(s): 13334
    10/17/2017 Authors: Caroti CM; Ahn H; Salazar HF; Joseph G; Sankar SB; Willett NJ; Wood LB; Taylor WR; Lyle AN
  • Decorin-containing collagen hydrogels as dimensionally stable scaffolds to study the effects of compressive mechanical loading on angiogenesis.
    MRS Commun Volume: 7 Page(s): 466 - 471
    09/01/2017 Authors: Ruehle MA; Krishnan L; LaBelle SA; Willett NJ; Weiss JA; Guldberg RE
  • Building better bone: The weaving of biologic and engineering strategies for managing bone loss.
    J Orthop Res Volume: 35 Page(s): 1855 - 1864
    09/01/2017 Authors: Schwartz AM; Schenker ML; Ahn J; Willett NJ
  • * Skeletal Myoblast-Seeded Vascularized Tissue Scaffolds in the Treatment of a Large Volumetric Muscle Defect in the Rat Biceps Femoris Muscle.
    Tissue Eng Part A Volume: 23 Page(s): 989 - 1000
    09/01/2017 Authors: Li M-T; Ruehle MA; Stevens HY; Servies N; Willett NJ; Karthikeyakannan S; Warren GL; Guldberg RE; Krishnan L
  • Altered Joint Loading Affects Cartilage Degeneration and Limb Function in Rats following Knee Meniscal Transection
    Volume: 49 Page(s): 949 - 949
    05/01/2017 Authors: Tsai L-C; Cooper ES; Hetzendorfer KM; Reece DS; Chang Y-H; Waters CR; Guldberg RE; Warren GL; Willett NJ
  • Implantable Sensors for Regenerative Medicine.
    J Biomech Eng Volume: 139 Page(s): 0210091 - 02100911
    02/01/2017 Authors: Klosterhoff BS; Tsang M; She D; Ong KG; Allen MG; Willett NJ; Guldberg RE
  • Augmented BMP-2 Release from Collagen Sponges Containing Microvascular Fragments
    Volume: 22 Page(s): S116 - S116
    12/01/2016 Authors: Ruehle MA; Krishnan L; Stevens HY; Willett NJ; Guldberg RE
  • A Wireless Sensor for Real-Time Measurements of Mechanical Strain in a Rodent Model of Segmental Bone Regeneration
    Volume: 22 Page(s): S40 - S40
    12/01/2016 Authors: Klosterhoff BS; Willett NJ; Guldberg RE; Ong K
  • Localized SDF-1 alpha Delivery Promotes Endogenous Cell Recruitment to the Supraspinatus Muscle After Severe Rotator Cuff Injury
    Volume: 22 Page(s): S5 - S5
    12/01/2016 Authors: Tellier LE; McFaline-Figueroa J; DeVos MJ; Botchwey EA; Jarrett CD; Willett NJ; Temenoff JS
  • Quantitative pre-clinical screening of therapeutics for joint diseases using contrast enhanced micro-computed tomography.
    Osteoarthritis Cartilage Volume: 24 Page(s): 1604 - 1612
    09/01/2016 Authors: Willett NJ; Thote T; Hart M; Moran S; Guldberg RE; Kamath RV
  • Dysregulation of miR-155 in Acute Oscillatory Shear Stress (OSS)-mediated Oxidative Stress, Inflammation and Endothelial Dysfunction
    Volume: 36
    05/01/2016 Authors: Mohamed I; Thomas S; Rooney K; Sutliff R; Willett N; Searles C
  • Guidelines for Models of Skeletal Muscle Injury and Therapeutic Assessment.
    Cells Tissues Organs Volume: 202 Page(s): 214 - 226
    01/01/2016 Authors: Willett NJ; Krishnan L; Li MTA; Guldberg RE; Warren GL
  • Effect of cell origin and timing of delivery for stem cell-based bone tissue engineering using biologically functionalized hydrogels.
    Tissue Eng Part A Volume: 21 Page(s): 156 - 165
    01/01/2015 Authors: Dosier CR; Uhrig BA; Willett NJ; Krishnan L; Li M-TA; Stevens HY; Schwartz Z; Boyan BD; Guldberg RE
  • Preclinical Models and Regenerative Strategies for Composite Limb Trauma
    Volume: 20 Page(s): S43 - S43
    12/01/2014 Authors: Guldberg R; Willett N; Krishnan L; Li M; Boerckel J; Uhrig B; Warren G
  • Small Animal Model of Juvenile Osteochondritis dissecans
    Volume: 20 Page(s): S134 - S135
    12/01/2014 Authors: Salazar-Noratto GE; Cobb DA; Willett NJ; Stevens HY; Lin ASP; Guldberg RE
  • Drug delivery: nanoengineered particles for enhanced intra-articular retention and delivery of proteins (adv. Healthcare mater. 10/2014).
    Adv Healthc Mater Volume: 3 Page(s): 1561
    10/01/2014 Authors: Singh A; Agarwal R; Diaz-Ruiz CA; Willett NJ; Wang P; Lee LA; Wang Q; Guldberg RE; Garca AJ
  • Nanoengineered particles for enhanced intra-articular retention and delivery of proteins.
    Adv Healthc Mater Volume: 3 Page(s): 1562 - 1525
    10/01/2014 Authors: Singh A; Agarwal R; Diaz-Ruiz CA; Willett NJ; Wang P; Lee LA; Wang Q; Guldberg RE; Garca AJ
  • Oxidized alginate hydrogels for bone morphogenetic protein-2 delivery in long bone defects.
    Acta Biomater Volume: 10 Page(s): 4390 - 4399
    10/01/2014 Authors: Priddy LB; Chaudhuri O; Stevens HY; Krishnan L; Uhrig BA; Willett NJ; Guldberg RE
  • Functional analysis of limb recovery following autograft treatment of volumetric muscle loss in the quadriceps femoris.
    J Biomech Volume: 47 Page(s): 2013 - 2021
    06/27/2014 Authors: Li MTA; Willett NJ; Uhrig BA; Guldberg RE; Warren GL
  • Particulated Juvenile Articular Cartilage Implantation in the Knee: A 3-Year EPIC-CT and Histological Examination.
    Cartilage Volume: 5 Page(s): 74 - 77
    04/01/2014 Authors: Stevens HY; Shockley BE; Willett NJ; Lin ASP; Raji Y; Guldberg RE; Labib SA
  • Intra-articular injection of micronized dehydrated human amnion/chorion membrane attenuates osteoarthritis development.
    Arthritis Res Ther Volume: 16 Page(s): R47
    02/06/2014 Authors: Willett NJ; Thote T; Lin ASP; Moran S; Raji Y; Sridaran S; Stevens HY; Guldberg RE
  • Vascularization strategies for bone regeneration.
    Ann Biomed Eng Volume: 42 Page(s): 432 - 444
    02/01/2014 Authors: Krishnan L; Willett NJ; Guldberg RE
  • Recovery from hind limb ischemia enhances rhBMP-2-mediated segmental bone defect repair in a rat composite injury model.
    Bone Volume: 55 Page(s): 410 - 417
    08/01/2013 Authors: Uhrig BA; Boerckel JD; Willett NJ; Li M-TA; Huebsch N; Guldberg RE
  • Localized 3D analysis of cartilage composition and morphology in small animal models of joint degeneration.
    Osteoarthritis Cartilage Volume: 21 Page(s): 1132 - 1141
    08/01/2013 Authors: Thote T; Lin ASP; Raji Y; Moran S; Stevens HY; Hart M; Kamath RV; Guldberg RE; Willett NJ
  • QUANTITATIVE 3D ANALYSIS OF CARTILAGE LESIONS AND OSTEOPHYTES IN A RAT OA MODEL USING CONTRAST BASED MICRO-CT IMAGING IN COMPARISON WITH HISTOPATHOLOGY
    Volume: 21 Page(s): S228 - S228
    04/01/2013 Authors: Thote T; Willett NJ; Lin AS; Moran S; Hart MA; Kamath RV; Guldberg RE
  • OSTEOARTHRITIS DEVELOPMENT IN A SURGICALLY INDUCED RAT MODEL IS ATTENUATED BY TREATMENT WITH MICRONIZED AMNIOTIC MEMBRANE
    Volume: 21 Page(s): S29 - S30
    04/01/2013 Authors: Willett NJ; Thote T; Lin AS; Moran S; Raji Y; Stevens HY; Guldberg RE
  • CONTRAST-BASED MICRO-CT ANALYSIS OF MMP INHIBITOR EFFICACY IN A RAT OSTEOARTHRITIS MODEL
    Volume: 21 Page(s): S227 - S227
    04/01/2013 Authors: Thote T; Willett NJ; Hart MA; Lin AS; Moran S; Guldberg RE; Kamath RV
  • Attenuated human bone morphogenetic protein-2-mediated bone regeneration in a rat model of composite bone and muscle injury.
    Tissue Eng Part C Methods Volume: 19 Page(s): 316 - 325
    04/01/2013 Authors: Willett NJ; Li M-TA; Uhrig BA; Boerckel JD; Huebsch N; Lundgren TL; Warren GL; Guldberg RE
  • Interactions between bone and vascular repair in a composite tissue limb injury model
    JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE Volume: 6 Page(s): 22 - 23
    09/01/2012 Authors: Uhrig B; Boerckel J; Willett N; Li M; Huebsch N; Guldberg R
  • Injectable micronized amniotic membrane attenuates the progression of osteoarthritis
    JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE Volume: 6 Page(s): 169 - 169
    09/01/2012 Authors: Willett NJ; Lin AS; Thote T; Moran SM; Raji Y; Guldberg RE
  • BMP-2 mediated tissue regeneration is attenuated in a rat model of composite bone and muscle injury
    JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE Volume: 6 Page(s): 23 - 23
    09/01/2012 Authors: Willett NJ; Li MA; Uhrig BA; Lundgren T; Boerckel JD; Warren GL; Guldberg RE
  • Mechanical regulation of vascular growth and tissue regeneration in vivo.
    Proc Natl Acad Sci U S A Volume: 108 Page(s): E674 - E680
    09/13/2011 Authors: Boerckel JD; Uhrig BA; Willett NJ; Huebsch N; Guldberg RE
  • Redox signaling in an in vivo murine model of low magnitude oscillatory wall shear stress.
    Antioxid Redox Signal Volume: 15 Page(s): 1369 - 1378
    09/01/2011 Authors: Willett NJ; Kundu K; Knight SF; Dikalov S; Murthy N; Taylor WR
  • An in vivo murine model of low-magnitude oscillatory wall shear stress to address the molecular mechanisms of mechanotransduction--brief report.
    Arterioscler Thromb Vasc Biol Volume: 30 Page(s): 2099 - 2102
    11/01/2010 Authors: Willett NJ; Long RC; Maiellaro-Rafferty K; Sutliff RL; Shafer R; Oshinski JN; Giddens DP; Guldberg RE; Taylor WR
  • In vivo assessment of blood flow patterns in abdominal aorta of mice with MRI: implications for AAA localization.
    Am J Physiol Heart Circ Physiol Volume: 297 Page(s): H1290 - H1295
    10/01/2009 Authors: Amirbekian S; Long RC; Consolini MA; Suo J; Willett NJ; Fielden SW; Giddens DP; Taylor WR; Oshinski JN
  • Hydrocyanines: a class of fluorescent sensors that can image reactive oxygen species in cell culture, tissue, and in vivo.
    Angew Chem Int Ed Engl Volume: 48 Page(s): 299 - 303
    01/01/2009 Authors: Kundu K; Knight SF; Willett N; Lee S; Taylor WR; Murthy N
  • Acute changes in shear stress induce expression of inflammatory proteins in a mouse coarctation model
    Volume: 27 Page(s): E100 - E100
    06/01/2007 Authors: Willett NJ; Ferrara DE; Suo J; Weiss D; Guldberg RE; Giddens DP; Taylor WR
  • Thermomechanics of the shape memory effect in polymers for biomedical applications.
    J Biomed Mater Res A Volume: 73 Page(s): 339 - 348
    06/01/2005 Authors: Gall K; Yakacki CM; Liu Y; Shandas R; Willett N; Anseth KS
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