Nicholas Varvel
- Department of Pharmacology & Chemical Biology
Assistant Professor
-
Emory University
Pharmacology and Chemical Biology
1510 Clifton Road, Suite 5002
Overview
Research Area:
Innate immune cell responses in epilepsy.
Academic Appointment
- Assistant Professor, Emory University School of Medicine
Education
Degrees
- PhD from Case Western Reserve University
- BS from University of Dayton
Research
Publications
-
Forged Without FIRE: Normal Brain Development in the Absence of Microglia.
Epilepsy Curr Page(s): 15357597251348961
06/16/2025 Authors: Varvel NH -
CCR2 antagonism identifies blood-borne monocytes as a target for prevention of cognitive deficits after seizures.
05/21/2025 Authors: Pourkhodadad S; Wang W; Dingledine R; Varvel NH -
Disease modification upon 2 weeks of tofacitinib treatment in a mouse model of chronic epilepsy.
Sci Transl Med Volume: 17 Page(s): eadt0527
03/19/2025 Authors: Hoffman OR; Koehler JL; Espina JEC; Patterson AM; Gohar ES; Coleman EM; Schoenike BA; Espinosa-Garcia C; Paredes F; Varvel NH -
Inflammation Emerges as a Sensitizer of a Heat-Responsive Cation Channel.
Epilepsy Curr Volume: 25 Page(s): 184 - 186
01/01/2025 Authors: Varvel NH -
Disease modification upon brief exposure to tofacitinib during chronic epilepsy.
bioRxiv
11/21/2024 Authors: Hoffman OR; Koehler JL; Espina JEC; Patterson AM; Gohar ES; Coleman E; Schoenike BA; Espinosa-Garcia C; Paredes F; Varvel NH -
Takin' Out the Trash for Brain Health!
Epilepsy Curr Volume: 24 Page(s): 292 - 294
01/01/2024 Authors: Varvel NH -
Pharmacological inhibition of the inflammatory receptor CCR2 relieves the early deleterious consequences of status epilepticus.
Sci Rep Volume: 13 Page(s): 5651
04/06/2023 Authors: Alemn-Ruiz C; Wang W; Dingledine R; Varvel NH -
Preclinical development of an EP2 antagonist for post-seizure cognitive deficits.
Neuropharmacology Volume: 224 Page(s): 109356
02/15/2023 Authors: Varvel NH; Amaradhi R; Espinosa-Garcia C; Duddy S; Franklin R; Banik A; Alemn-Ruiz C; Blackmer-Raynolds L; Wang W; Honore T -
Progranulin loss results in sex-dependent dysregulation of the peripheral and central immune system.
Front Immunol Volume: 13 Page(s): 1056417
01/01/2022 Authors: Houser MC; Uriarte Huarte O; Wallings RL; Keating CE; MacPherson KP; Herrick MK; Kannarkat GT; Kelly SD; Chang J; Varvel NH -
Peripheral Myeloid Cell EP2 Activation Contributes to the Deleterious Consequences of Status Epilepticus.
J Neurosci Volume: 41 Page(s): 1105 - 1117
02/03/2021 Authors: Varvel NH; Espinosa-Garcia C; Hunter-Chang S; Chen D; Biegel A; Hsieh A; Blackmer-Raynolds L; Ganesh T; Dingledine R