Publications

• Contributions of Genetic Variation in Astrocytes to Cell and Molecular Mechanisms of Risk and Resilience to Late-Onset Alzheimer's Disease.
  Glia Volume: 73 Page(s): 1166 - 1187
  06/01/2025 Authors: Lee H; Pearse RV; Lish AM; Pan C; Augur ZM; Terzioglu G; Gaur P; Liao M; Fujita M; Tio ES
• Correction: EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair.
  Oncogene Volume: 44 Page(s): 928 - 930
  04/01/2025 Authors: Koyen AE; Madden MZ; Park D; Minten EV; Kapoor-Vazirani P; Werner E; Pfister NT; Haji-Seyed-Javadi R; Zhang H; Xu J
• Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia.
  Nat Med Volume: 31 Page(s): 1267 - 1275
  04/01/2025 Authors: Llibre-Guerra JJ; Fernandez MV; Joseph-Mathurin N; Bian S; Carter K; Li Y; Aschenbrenner AJ; Pottier C; Sigurdson W; McDade E
• ALS plasma biomarkers reveal neurofilament and pTau correlate with disease onset and progression.
  Ann Clin Transl Neurol Volume: 12 Page(s): 714 - 723
  04/01/2025 Authors: Thomas EV; Han C; Kim WJ; Asress S; Li Y; Taylor JA; Gearing M; Fournier CN; McEachin ZT; Seyfried NT
• Mapping medically relevant RNA isoform diversity in the aged human frontal cortex with deep long-read RNA-seq.
  Nat Biotechnol Volume: 43 Page(s): 635 - 646
  04/01/2025 Authors: Aguzzoli Heberle B; Brandon JA; Page ML; Nations KA; Dikobe KI; White BJ; Gordon LA; Fox GA; Wadsworth ME; Doyle PH
• Translating the Post-Mortem Brain Multi-Omics Molecular Taxonomy of Alzheimer's Dementia to Living Humans.
  bioRxiv
  03/24/2025 Authors: Iturria-Medina Y; Poole VN; Zammit AR; Yu L; Tasaki S; Hong JH; Lopes KDP; Batalha C; Ridwan AR; Vialle RA
• Brain 5-hydroxymethylcytosine alterations are associated with Alzheimer's disease neuropathology.
  Nat Commun Volume: 16 Page(s): 2842
  03/22/2025 Authors: Zhao J; Gu T; Gao C; Miao G; Palma-Gudiel H; Yu L; Yang J; Wang Y; Li Y; Lim J
• Proteomic Subtyping of Alzheimer's Disease CSF links Blood-Brain Barrier Dysfunction to Reduced levels of Tau and Synaptic Biomarkers.
  
  03/15/2025 Authors: Bangs MC; Gadhavi J; Carter EK; Ping L; Duong DM; Dammer EB; Wu F; Shantaraman A; Fox EJ; Johnson ECB
• Longitudinal multi-omics in alpha-synuclein Drosophila model discriminates disease- from age-associated pathologies in Parkinson's disease.
  NPJ Parkinsons Dis Volume: 11 Page(s): 46
  03/11/2025 Authors: Moore J; Wu T; Dhindsa J; El Fadel O; Le A; Perez A; Amoh B; Tarkunde A; Zhu KF; Avalos M
• Structural variants linked to Alzheimer's disease and other common age-related clinical and neuropathologic traits.
  Genome Med Volume: 17 Page(s): 20
  03/04/2025 Authors: Vialle RA; de Paiva Lopes K; Li Y; Ng B; Schneider JA; Buchman AS; Wang Y; Farfel JM; Barnes LL; Wingo AP
• Plasma Biomarkers for Cerebral Amyloid Angiopathy and Implications for Amyloid-Related Imaging Abnormalities: A Comprehensive Review.
  J Clin Med Volume: 14
  02/07/2025 Authors: Sin M-K; Dage JL; Nho K; Dowling NM; Seyfried NT; Bennett DA; Levey AI; Ahmed A
• Simultaneous profiling of native-state proteomes and transcriptomes of neural cell types using proximity labeling.
  
  02/01/2025 Authors: Ramelow CC; Dammer EB; Xiao H; Cheng L; Kumar P; Espinosa-Garcia C; Sampson MM; Nelson RS; Malepati S; Kour D
• Proximity labeling of the Tau repeat domain enriches RNA-binding proteins that are altered in Alzheimer's disease and related tauopathies.
  bioRxiv
  01/22/2025 Authors: Shapley SM; Shantaraman A; Kearney MA; Dammer EB; Duong DM; Bowen CA; Bagchi P; Guo Q; Rangaraju S; Seyfried NT
• APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology.
  Mol Neurodegener Volume: 20 Page(s): 9
  01/22/2025 Authors: Tran KM; Kwang NE; Butler CA; Gomez-Arboledas A; Kawauchi S; Mar C; Chao D; Barahona RA; Da Cunha C; Tsourmas KI
• Identification of novel Kv1.3 channel-interacting proteins using proximity labelling in T-cells.
  bioRxiv
  01/18/2025 Authors: Kour D; Bowen CA; Srivastava U; Nguyen HM; Kumari R; Kumar P; Brandelli AD; Bitarafan S; Tobin BR; Wood L
• Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer's disease.
  Alzheimers Res Ther Volume: 17 Page(s): 5
  01/04/2025 Authors: Valdes P; Caldwell AB; Liu Q; Fitzgerald MQ; Ramachandran S; Karch CM; Dominantly Inherited Alzheimer Network (DIAN); Galasko DR; Yuan SH; Wagner SL
• Stratifying risk of Alzheimer's disease in healthy middle-aged individuals with machine learning.
  Brain Commun Volume: 7 Page(s): fcaf121
  01/01/2025 Authors: Tandon R; Zhao L; Watson CM; Sarkar N; Elmor M; Heilman C; Sanders K; Hales CM; Yang H; Loring DW
• CSF proteomics reveals changes in myelin and synaptic biology after Spectris treatment.
  Alzheimers Dement (N Y) Volume: 11 Page(s): e70051
  01/01/2025 Authors: Hajs M; Pandey K; Singer AC; Duong D; Bitarafan S; Shpokayte M; Malchano Z; Kern R; Lah JJ; Levey AI
• Marmosets as model systems for the study of Alzheimer's disease and related dementias: Substantiation of physiological tau 3R and 4R isoform expression and phosphorylation.
  Alzheimers Dement Volume: 21 Page(s): e14366
  01/01/2025 Authors: Huhe H; Shapley SM; Duong DM; Wu F; Ha S-K; Choi S-H; Kofler J; Mou Y; Guimaraes TR; Thathiah A
• Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50.
  Elife Volume: 13
  12/16/2024 Authors: Paz E; Jain S; Gottfried I; Staretz-Chacham O; Mahajnah M; Bagchi P; Seyfried NT; Ashery U; Azem A
• Genetic architecture of epigenetic cortical clock age in brain tissue from older individuals: alterations in CD46 and other loci.
  Epigenetics Volume: 19 Page(s): 2392050
  12/01/2024 Authors: Grodstein F; Lemos B; Yang J; de Paiva Lopes K; Vialle RA; Seyfried N; Wang Y; Shireby G; Hannon E; Thomas A
• Large-scale deep proteomic analysis in Alzheimer's disease brain regions across race and ethnicity.
  Alzheimers Dement Volume: 20 Page(s): 8878 - 8897
  12/01/2024 Authors: Seifar F; Fox EJ; Shantaraman A; Liu Y; Dammer EB; Modeste E; Duong DM; Yin L; Trautwig AN; Guo Q
• Basic Science and Pathogenesis.
  Alzheimers Dement Volume: 20 Suppl 1 Page(s): e090590
  12/01/2024 Authors: Reddy JS; Heath LM; Allen M; Poehlman WL; Wang Y; Johnson R; Wang E; Ma Y; Ho CCG; Lopes KDP
• Basic Science and Pathogenesis.
  Alzheimers Dement Volume: 20 Suppl 1 Page(s): e089491
  12/01/2024 Authors: Zhao P; Fadel OE; Le A; Mangleburg CG; Wu T; Dhindsa J; Amoh BK; Marella AS; Li Y; Seyfried NT
• Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer's disease.
  Nat Commun Volume: 15 Page(s): 9982
  11/18/2024 Authors: Hofmann A; Hsler LM; Lambert M; Kaeser SA; Grber-Sultan S; Obermller U; Kuder-Buletta E; la Fougere C; Laske C; Vglein J
• Integration across biophysical scales identifies molecular and cellular correlates of person-to-person variability in human brain connectivity.
  Nat Neurosci Volume: 27 Page(s): 2240 - 2252
  11/01/2024 Authors: Ng B; Tasaki S; Greathouse KM; Walker CK; Zhang A; Covitz S; Cieslak M; Weber AJ; Adamson AB; Andrade JP
• Network Analysis of Brain and Bone Tissue Transcripts Reveals Shared Molecular Mechanisms Underlying Alzheimer's Disease and Related Dementias and Osteoporosis.
  J Gerontol A Biol Sci Med Sci Volume: 79
  11/01/2024 Authors: Nagarajan A; Laird J; Ugochukwu O; Reppe S; Gautvik K; Ross RD; Bennett DA; Rosen C; Kiel DP; Higginbotham LA
• CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease.
  Cell Volume: 187 Page(s): 6309 - 6326.e15
  10/31/2024 Authors: Shen Y; Timsina J; Heo G; Beric A; Ali M; Wang C; Yang C; Wang Y; Western D; Liu M
• Correction: Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease.
  Mol Neurodegener Volume: 19 Page(s): 71
  10/11/2024 Authors: Shantaraman A; Dammer EB; Ugochukwu O; Duong DM; Yin L; Carter EK; Gearing M; Chen-Plotkin A; Lee EB; Trojanowski JQ
• Heparin-enriched plasma proteome is significantly altered in Alzheimer's disease.
  Mol Neurodegener Volume: 19 Page(s): 67
  10/08/2024 Authors: Guo Q; Ping L; Dammer EB; Duong DM; Yin L; Xu K; Shantaraman A; Fox EJ; Golde TE; Johnson ECB
• Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity.
  Hum Mol Genet Volume: 33 Page(s): 1815 - 1832
  10/07/2024 Authors: Pavekovi M; De-Paula RB; Ojelade SA; Tantry EK; Kochukov MY; Bao S; Veeraragavan S; Garza AR; Srivastava S; Song S-Y
• Author Correction: Serum proteomics reveal APOE-4-dependent and APOE-4-independent protein signatures in Alzheimer's disease.
  Nat Aging Volume: 4 Page(s): 1509
  10/01/2024 Authors: Frick EA; Emilsson V; Jonmundsson T; Steindorsdottir AE; Johnson ECB; Puerta R; Dammer EB; Shantaraman A; Cano A; Boada M
• Bridging the gap: Multi-omics profiling of brain tissue in Alzheimer's disease and older controls in multi-ethnic populations.
  Alzheimers Dement Volume: 20 Page(s): 7174 - 7192
  10/01/2024 Authors: Reddy JS; Heath L; Linden AV; Allen M; Lopes KDP; Seifar F; Wang E; Ma Y; Poehlman WL; Quicksall ZS
• CT1812 biomarker signature from a meta-analysis of CSF proteomic findings from two Phase 2 clinical trials in Alzheimer's disease.
  Alzheimers Dement Volume: 20 Page(s): 6860 - 6880
  10/01/2024 Authors: Lizama BN; Williams C; North HA; Pandey K; Duong D; Di Caro V; Mecca AP; Blennow K; Zetterberg H; Levey AI
• Serum proteomics reveal APOE-4-dependent and APOE-4-independent protein signatures in Alzheimer's disease.
  Nat Aging Volume: 4 Page(s): 1446 - 1464
  10/01/2024 Authors: Frick EA; Emilsson V; Jonmundsson T; Steindorsdottir AE; Johnson ECB; Puerta R; Dammer EB; Shantaraman A; Cano A; Boada M
• Biochemical and neurophysiological effects of deficiency of the mitochondrial import protein TIMM50.
  bioRxiv
  09/21/2024 Authors: Paz E; Jain S; Gottfried I; Staretz-Chacham O; Mahajnah M; Bagchi P; Seyfried NT; Ashery U; Azem A
• Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology.
  Nat Commun Volume: 15 Page(s): 7918
  09/10/2024 Authors: Goettemoeller AM; Banks E; Kumar P; Olah VJ; McCann KE; South K; Ramelow CC; Eaton A; Duong DM; Seyfried NT
• Omnibus proteome-wide association study identifies 43 risk genes for Alzheimer disease dementia.
  Am J Hum Genet Volume: 111 Page(s): 1848 - 1863
  09/05/2024 Authors: Hu T; Parrish RL; Dai Q; Buchman AS; Tasaki S; Bennett DA; Seyfried NT; Epstein MP; Yang J
• An interim exploratory proteomics biomarker analysis of a phase 2 clinical trial to assess the impact of CT1812 in Alzheimer's disease.
  Neurobiol Dis Volume: 199 Page(s): 106575
  09/01/2024 Authors: Lizama BN; North HA; Pandey K; Williams C; Duong D; Cho E; Di Caro V; Ping L; Blennow K; Zetterberg H
• Integrative proteomics identifies a conserved A amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer's disease.
  Cell Rep Med Volume: 5 Page(s): 101669
  08/20/2024 Authors: Levites Y; Dammer EB; Ran Y; Tsering W; Duong D; Abreha M; Gadhavi J; Lolo K; Trejo-Lopez J; Phillips J
• Structural variants linked to Alzheimer's Disease and other common age-related clinical and neuropathologic traits.
  
  08/13/2024 Authors: Vialle RA; de Paiva Lopes K; Li Y; Ng B; Schneider JA; Buchman AS; Wang Y; Farfel JM; Barnes LL; Wingo AP
• Dendritic spine head diameter predicts episodic memory performance in older adults.
  Sci Adv Volume: 10 Page(s): eadn5181
  08/09/2024 Authors: Walker CK; Liu E; Greathouse KM; Adamson AB; Wilson JP; Poovey EH; Curtis KA; Muhammad HM; Weber AJ; Bennett DA
• Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease.
  Mol Neurodegener Volume: 19 Page(s): 60
  08/06/2024 Authors: Shantaraman A; Dammer EB; Ugochukwu O; Duong DM; Yin L; Carter EK; Gearing M; Chen-Plotkin A; Lee EB; Trojanowski JQ
• Proteomic networks of gray and white matter reveal tissue-specific changes in human tauopathy.
  Ann Clin Transl Neurol Volume: 11 Page(s): 2138 - 2152
  08/01/2024 Authors: Johnson AG; Dammer EB; Webster JA; Duong DM; Seyfried NT; Hales CM
• Proximity Labeling Proteomics Reveals Kv1.3 Potassium Channel Immune Interactors in Microglia.
  Mol Cell Proteomics Volume: 23 Page(s): 100809
  08/01/2024 Authors: Bowen CA; Nguyen HM; Lin Y; Bagchi P; Natu A; Espinosa-Garcia C; Werner E; Kumari R; Brandelli AD; Kumar P
• Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology.
  
  07/05/2024 Authors: Goettemoeller AM; Banks E; Kumar P; Olah VJ; McCann KE; South K; Ramelow CC; Eaton A; Duong DM; Seyfried NT
• Psychosocial experiences are associated with human brain mitochondrial biology.
  Proc Natl Acad Sci U S A Volume: 121 Page(s): e2317673121
  07/02/2024 Authors: Trumpff C; Monzel AS; Sandi C; Menon V; Klein H-U; Fujita M; Lee A; Petyuk VA; Hurst C; Duong DM
• Proteins linking APOE 4 with Alzheimer's disease.
  Alzheimers Dement Volume: 20 Page(s): 4499 - 4511
  07/01/2024 Authors: Oveisgharan S; Yu L; de Paiva Lopes K; Tasaki S; Wang Y; Menon V; Schneider JA; Seyfried NT; Bennett DA
• Proteomic analysis of Alzheimer's disease cerebrospinal fluid reveals alterations associated with APOE 4 and atomoxetine treatment.
  Sci Transl Med Volume: 16 Page(s): eadn3504
  06/26/2024 Authors: Dammer EB; Shantaraman A; Ping L; Duong DM; Gerasimov ES; Ravindran SP; Gudmundsdottir V; Frick EA; Gomez GT; Walker KA
• Lowering Hippocampal miR-29a Expression Slows Cognitive Decline and Reduces Beta-Amyloid Deposition in 5FAD Mice.
  Mol Neurobiol Volume: 61 Page(s): 3343 - 3356
  06/01/2024 Authors: Mei Z; Liu J; Schroeder JP; Weinshenker D; Duong DM; Seyfried NT; Li Y; Jin P; Wingo AP; Wingo TS
• Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid.
  Alzheimers Dement Volume: 20 Page(s): 4043 - 4065
  06/01/2024 Authors: Wojtas AM; Dammer EB; Guo Q; Ping L; Shantaraman A; Duong DM; Yin L; Fox EJ; Seifar F; Lee EB
• Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood.
  Science Volume: 384 Page(s): eadh3707
  05/24/2024 Authors: Daskalakis NP; Iatrou A; Chatzinakos C; Jajoo A; Snijders C; Wylie D; DiPietro CP; Tsatsani I; Chen C-Y; Pernia CD
• Deconstructing pathological tau by biological process in early stages of Alzheimer disease: a method for quantifying tau spatial spread in neuroimaging.
  EBioMedicine Volume: 103 Page(s): 105080
  05/01/2024 Authors: Doering S; McCullough A; Gordon BA; Chen CD; McKay N; Hobbs D; Keefe S; Flores S; Scott J; Smith H
• Associations of brain morphology with cortical proteins of cognitive resilience.
  Neurobiol Aging Volume: 137 Page(s): 1 - 7
  05/01/2024 Authors: Poole VN; Ridwan AR; Arfanakis K; Dawe RJ; Seyfried NT; De Jager PL; Schneider JA; Leurgans SE; Yu L; Bennett DA
• Marmosets as model systems for the study of Alzheimer's disease and related dementias: substantiation of physiological Tau 3R and 4R isoform expression and phosphorylation.
  bioRxiv
  04/29/2024 Authors: Huhe H; Shapley SM; Duong D; Wu F; Ha S-K; Choi S-H; Kofler J; Mou Y; Guimaraes TR; Thathiah A
• Glycoproteome-Wide Discovery of Cortical Glycoproteins That May Provide Cognitive Resilience in Older Adults.
  Neurology Volume: 102 Page(s): e209223
  04/09/2024 Authors: Buchman AS; Yu L; Klein H-U; Zammit AR; Oveisgharan S; Nag S; Tickotsky N; Levy H; Seyfried N; Morgenstern D
• Person-specific differences in ubiquitin-proteasome mediated proteostasis in human neurons.
  Alzheimers Dement Volume: 20 Page(s): 2952 - 2967
  04/01/2024 Authors: Hsieh Y-C; Augur ZM; Arbery M; Ashour N; Barrett K; Pearse RV; Tio ES; Duong DM; Felsky D; De Jager PL
• Native-state proteomics of Parvalbumin interneurons identifies unique molecular signatures and vulnerabilities to early Alzheimer's pathology.
  Nat Commun Volume: 15 Page(s): 2823
  04/01/2024 Authors: Kumar P; Goettemoeller AM; Espinosa-Garcia C; Tobin BR; Tfaily A; Nelson RS; Natu A; Dammer EB; Santiago JV; Malepati S
• Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration.
  
  03/28/2024 Authors: Saloner R; Staffaroni A; Dammer E; Johnson ECB; Paolillo E; Wise A; Heuer H; Forsberg L; Lago AL; Webb J
• Integrative brain omics approach reveals key role for sn-1 lysophosphatidylethanolamine in Alzheimer's dementia.
  
  02/27/2024 Authors: Ortlund E; Chen C-Y; Maner-Smith K; Khadka M; Ahn J; Gulbin X; Ivanova A; Dammer E; Seyfried N; Bennett D
• Heparin-enriched plasma proteome is significantly altered in Alzheimer's Disease.
  Res Sq
  02/23/2024 Authors: Guo Q; Ping L; Dammer EB; Yin L; Xu K; Shantaraman A; Fox EJ; Golde TE; Johnson ECB; Roberts BR
• Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
  Sci Transl Med Volume: 16 Page(s): eadg7162
  02/14/2024 Authors: Seddighi S; Qi YA; Brown A-L; Wilkins OG; Bereda C; Belair C; Zhang Y-J; Prudencio M; Keuss MJ; Khandeshi A
• Cryptic exon inclusion is a molecular signature ofLATE-NCin aging brains.
  Acta Neuropathol Volume: 147 Page(s): 29
  02/03/2024 Authors: Chung M; Carter EK; Veire AM; Dammer EB; Chang J; Duong DM; Raj N; Bassell GJ; Glass JD; Gendron TF
• Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease.
  
  01/24/2024 Authors: Shantaraman A; Dammer EB; Ugochukwu O; Duong DM; Yin L; Carter EK; Gearing M; Chen-Plotkin A; Lee EB; Trojanowski JQ
• TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia.
  Sci Transl Med Volume: 16 Page(s): eadf9735
  01/17/2024 Authors: Marks JD; Ayuso VE; Carlomagno Y; Yue M; Todd TW; Hao Y; Li Z; McEachin ZT; Shantaraman A; Duong DM
• Systematic proteomics in Autosomal dominant Alzheimer's disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways.
  medRxiv
  01/13/2024 Authors: Shen Y; Ali M; Timsina J; Wang C; Do A; Western D; Liu M; Gorijala P; Budde J; Liu H
• Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid.
  
  01/11/2024 Authors: Wojtas AM; Dammer EB; Guo Q; Ping L; Shantaraman A; Duong DM; Yin L; Fox EJ; Seifar F; Lee EB
• OXR1 maintains the retromer to delay brain aging under dietary restriction.
  Nat Commun Volume: 15 Page(s): 467
  01/11/2024 Authors: Wilson KA; Bar S; Dammer EB; Carrera EM; Hodge BA; Hilsabeck TAU; Bons J; Brownridge GW; Beck JN; Rose J
• Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease.
  
  01/09/2024 Authors: Gudmundsdottir V; Frick E; Emilsson V; Jonmundsson T; Steindorsdottir A; Johnson ECB; Puerta R; Dammer E; Shantaraman A; Cano A
• Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities.
  Neurology Volume: 102 Page(s): e207816
  01/09/2024 Authors: Zammit AR; Klein H-U; Yu L; Levey AI; Seyfried NT; Wingo AP; Wingo TS; Schneider JA; Bennett DA; Buchman AS
• Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease.
  Biomolecules Volume: 14
  01/03/2024 Authors: Wang E; Pan AL; Bagchi P; Rangaraju S; Seyfried NT; Ehrlich ME; Salton SR; Zhang B
• Associations of cortical SPP1 and ITGAX with cognition and common neuropathologies in older adults.
  Alzheimers Dement Volume: 20 Page(s): 525 - 537
  01/01/2024 Authors: Lopes KDP; Yu L; Shen X; Qiu Y; Tasaki S; Iatrou A; Beeri MS; Seyfried NT; Menon V; Wang Y
• Using deep long-read RNAseq in Alzheimer's disease brain to assess medical relevance of RNA isoform diversity.
  bioRxiv
  12/11/2023 Authors: Heberle BA; Brandon JA; Page ML; Nations KA; Dikobe KI; White BJ; Gordon LA; Fox GA; Wadsworth ME; Doyle PH
• A Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease.
  bioRxiv
  12/07/2023 Authors: Levites Y; Dammer EB; Ran Y; Tsering W; Duong D; Abreha M; Gadhavi J; Lolo K; Trejo-Lopez J; Phillips JL
• Identification of State-Specific Proteomic and Transcriptomic Signatures of Microglia-Derived Extracellular Vesicles.
  Mol Cell Proteomics Volume: 22 Page(s): 100678
  12/01/2023 Authors: Santiago JV; Natu A; Ramelow CC; Rayaprolu S; Xiao H; Kumar V; Kumar P; Seyfried NT; Rangaraju S
• INPP5D regulates inflammasome activation in human microglia.
  Nat Commun Volume: 14 Page(s): 7552
  11/29/2023 Authors: Chou V; Pearse RV; Aylward AJ; Ashour N; Taga M; Terzioglu G; Fujita M; Fancher SB; Sigalov A; Benoit CR
• Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease.
  medRxiv
  11/09/2023 Authors: Frick EA; Emilsson V; Jonmundsson T; Steindorsdottir AE; Johnson ECB; Puerta R; Dammer EB; Shantaraman A; Cano A; Boada M
• Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction.
  Res Sq
  11/08/2023 Authors: Bar S; Wilson KA; Hilsabeck TAU; Alderfer S; Dammer EB; Burton JB; Shah S; Holtz A; Carrera EM; Beck JN
• Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology.
  Res Sq
  11/06/2023 Authors: Goettemoeller AM; Banks E; McCann KE; Kumar P; South K; Olah VJ; Ramelow CC; Duong DM; Seyfried NT; Rangaraju S
• Proteomic Network Analysis of Alzheimer's Disease Cerebrospinal Fluid Reveals Alterations Associated with APOE 4 Genotype and Atomoxetine Treatment.
  medRxiv
  10/30/2023 Authors: Dammer EB; Shantaraman A; Ping L; Duong DM; Gerasimov ES; Ravindran SP; Gudmundsdottir V; Frick EA; Gomez GT; Walker KA
• Proteomic signaling of dual specificity phosphatase 4 (DUSP4) in Alzheimer's disease.
  Res Sq
  10/19/2023 Authors: Wang E; Pan AL; Bagchi P; Ranjaraju S; Seyfried NT; Ehrlich ME; Salton SR; Zhang B
• Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment.
  Neurobiol Dis Volume: 186 Page(s): 106286
  10/01/2023 Authors: Higginbotham L; Carter EK; Dammer EB; Haque RU; Johnson ECB; Duong DM; Yin L; De Jager PL; Bennett DA; Felsky D
• Correction to 'DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining'.
  Nucleic Acids Res Volume: 51 Page(s): 9507
  09/22/2023
• Proteomic signaling of dual specificity phosphatase 4 (DUSP4) in Alzheimer's disease.
  bioRxiv
  09/14/2023 Authors: Wang E; Pan AL; Bagchi P; Ranjaraju S; Seyfried NT; Ehrlich ME; Salton SR; Zhang B
• A protein panel in cerebrospinal fluid for diagnostic and predictive assessment of Alzheimer's disease.
  Sci Transl Med Volume: 15 Page(s): eadg4122
  09/06/2023 Authors: Haque R; Watson CM; Liu J; Carter EK; Duong DM; Lah JJ; Wingo AP; Roberts BR; Johnson ECB; Saykin AJ
• Sex differences in brain protein expression and disease.
  Nat Med Volume: 29 Page(s): 2224 - 2232
  09/01/2023 Authors: Wingo AP; Liu Y; Gerasimov ES; Vattathil SM; Liu J; Cutler DJ; Epstein MP; Blokland GAM; Thambisetty M; Troncoso JC
• Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer's disease risk gene SORL1.
  Cell Rep Volume: 42 Page(s): 112994
  08/29/2023 Authors: Lee H; Aylward AJ; Pearse RV; Lish AM; Hsieh Y-C; Augur ZM; Benoit CR; Chou V; Knupp A; Pan C
• DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining.
  Nucleic Acids Res Volume: 51 Page(s): 7972 - 7987
  08/25/2023 Authors: Head PE; Kapoor-Vazirani P; Nagaraju GP; Zhang H; Rath SK; Luong NC; Haji-Seyed-Javadi R; Sesay F; Wang S-Y; Duong DM
• Integration of plasma and CSF metabolomics with CSF proteomic reveals novel associations between lipid mediators and central nervous system vascular and energy metabolism.
  Sci Rep Volume: 13 Page(s): 13752
  08/23/2023 Authors: Borkowski K; Seyfried NT; Arnold M; Lah JJ; Levey AI; Hales CM; Dammer EB; Blach C; Louie G; Kaddurah-Daouk R
• Lowering hippocampal miR-29a expression slows cognitive decline and reduces beta-amyloid deposition in 5xFAD mice.
  Res Sq
  08/16/2023 Authors: Mei Z; Liu J; Schroeder JP; Weinshenker D; Duong DM; Seyfried NT; Li Y; Jin P; Wingo AP; Wingo TS
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• Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease.
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• Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity.
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• Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer's Disease.
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• Interrogating the Metabolomic Profile of Amyotrophic Lateral Sclerosis in the Post-Mortem Human Brain by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI) Mass Spectrometry Imaging (MSI).
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• OXR1 STABILIZES THE RETROMER TO EXTEND LIFESPAN AND NEURONAL HEALTH BY DIETARY RESTRICTION
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• Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease.
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• Brain microRNAs are associated with variation in cognitive trajectory in advanced age.
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• Brain Cell Type-Specific Nuclear Proteomics Is Imperative to Resolve Neurodegenerative Disease Mechanisms.
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• Exploring Cortical Proteins Underlying the Relation of Neuroticism to Cognitive Resilience.
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• Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains.
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• EARLY ENRICHMENT OF IMMUNOGLOBULINS IN TBI-INDUCED NEURODEGENERATION
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  J Biol Chem Volume: 296 Page(s): 100760
  01/01/2021 Authors: Abreha MH; Ojelade S; Dammer EB; McEachin ZT; Duong DM; Gearing M; Bassell GJ; Lah JJ; Levey AI; Shulman JM
• Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer's Disease.
  Front Mol Neurosci Volume: 14 Page(s): 623659
  01/01/2021 Authors: Guo Q; Dammer EB; Zhou M; Kundinger SR; Gearing M; Lah JJ; Levey AI; Shulman JM; Seyfried NT
• Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau.
  Neuropsychopharmacology Volume: 46 Page(s): 98 - 115
  01/01/2021 Authors: Rayaprolu S; Higginbotham L; Bagchi P; Watson CM; Zhang T; Levey AI; Rangaraju S; Seyfried NT
• Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons.
  JAMA Psychiatry Volume: 77 Page(s): 1172 - 1180
  11/01/2020 Authors: Yu L; Tasaki S; Schneider JA; Arfanakis K; Duong DM; Wingo AP; Wingo TS; Kearns N; Thatcher GRJ; Seyfried NT
• Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.
  Sci Data Volume: 7 Page(s): 340
  10/12/2020 Authors: Sieberts SK; Perumal TM; Carrasquillo MM; Allen M; Reddy JS; Hoffman GE; Dang KK; Calley J; Ebert PJ; Eddy J
• Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations.
  Acta Neuropathol Commun Volume: 8 Page(s): 163
  10/07/2020 Authors: Huang M; Modeste E; Dammer E; Merino P; Taylor G; Duong DM; Deng Q; Holler CJ; Gearing M; Dickson D
• Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease.
  Sci Adv Volume: 6
  10/01/2020 Authors: Higginbotham L; Ping L; Dammer EB; Duong DM; Zhou M; Gearing M; Hurst C; Glass JD; Factor SA; Johnson ECB
• Deep Proteomic Analysis of Alzheimer Disease Brain Identifies New Protein Co-Expression Modules Associated with Disease That are Not Observed at the RNA Level
  Volume: 88 Page(s): S96 - S96
  10/01/2020 Authors: Johnson ECB; Dammer EB; Carter EK; Duong DM; Ping L; Yin L; Lah JJ; Levey AI; Seyfried NT
• Integrated analysis of the aging brain transcriptome and proteome in tauopathy.
  Mol Neurodegener Volume: 15 Page(s): 56
  09/29/2020 Authors: Mangleburg CG; Wu T; Yalamanchili HK; Guo C; Hsieh Y-C; Duong DM; Dammer EB; De Jager PL; Seyfried NT; Liu Z
• Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease.
  Sci Data Volume: 7 Page(s): 315
  09/28/2020 Authors: Ping L; Kundinger SR; Duong DM; Yin L; Gearing M; Lah JJ; Levey AI; Seyfried NT
• Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
  Cell Rep Volume: 32 Page(s): 108091
  09/01/2020 Authors: Ouellette AR; Neuner SM; Dumitrescu L; Anderson LC; Gatti DM; Mahoney ER; Bubier JA; Churchill G; Peters L; Huentelman MJ
• Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease.
  Nat Commun Volume: 11 Page(s): 3942
  08/07/2020 Authors: Beckmann ND; Lin W-J; Wang M; Cohain AT; Charney AW; Wang P; Ma W; Wang Y-C; Jiang C; Audrain M
• Publisher Correction: Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain.
  Nat Neurosci Volume: 23 Page(s): 1034
  08/01/2020 Authors: Wingo AP; Fan W; Duong DM; Gerasimov ES; Dammer EB; Liu Y; Harerimana NV; White B; Thambisetty M; Troncoso JC
• Proteomic Analysis of Human Immune Responses to Live-Attenuated Tularemia Vaccine.
  Vaccines (Basel) Volume: 8
  07/24/2020 Authors: Chang Y-H; Duong DM; Goll JB; Wood DC; Jensen TL; Yin L; Gelber CE; Seyfried NT; Anderson E; Natrajan MS
• Identification of Conserved Proteomic Networks in Neurodegenerative Dementia.
  Cell Rep Volume: 31 Page(s): 107807
  06/23/2020 Authors: Swarup V; Chang TS; Duong DM; Dammer EB; Dai J; Lah JJ; Johnson ECB; Seyfried NT; Levey AI; Geschwind DH
• Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain.
  Nat Neurosci Volume: 23 Page(s): 696 - 700
  06/01/2020 Authors: Wingo AP; Fan W; Duong DM; Gerasimov ES; Dammer EB; Liu Y; Harerimana NV; White B; Thambisetty M; Troncoso JC
• EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair.
  Oncogene Volume: 39 Page(s): 4798 - 4813
  06/01/2020 Authors: Koyen AE; Madden MZ; Park D; Minten EV; Kapoor-Vazirani P; Werner E; Pfister NT; Haji-Seyed-Javadi R; Zhang H; Xu J
• Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease.
  Mol Neurodegener Volume: 15 Page(s): 28
  05/07/2020 Authors: Rayaprolu S; Gao T; Xiao H; Ramesha S; Weinstock LD; Shah J; Duong DM; Dammer EB; Webster JA; Lah JJ
• Functional Analyses of Genetic Risk Variants of Depression-Related Phenotypes in the Human Brain
  Volume: 87 Page(s): S174 - S175
  05/01/2020 Authors: Harerimana N; Liu Y; Gerasimov ES; Robins C; Duong DM; Lah JJ; Bennett DA; Levey AI; Seyfried NT; Wingo TS
• Human Brain Proteome-Wide Association Study of Depression Identified 24 Proteins as Tractable Targets for Further Mechanistic Studies
  Volume: 87 Page(s): S183 - S183
  05/01/2020 Authors: Wingo TS; Liu Y; Lori A; Gerasimov ES; Duong DM; Dammer E; Ressler K; Lah J; Bennett D; Seyfried NT
• Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.
  Nat Med Volume: 26 Page(s): 769 - 780
  05/01/2020 Authors: Johnson ECB; Dammer EB; Duong DM; Ping L; Zhou M; Yin L; Higginbotham LA; Guajardo A; White B; Troncoso JC
• Middle-Down Proteomics Reveals Dense Sites of Methylation and Phosphorylation in Arginine-Rich RNA-Binding Proteins.
  J Proteome Res Volume: 19 Page(s): 1574 - 1591
  04/03/2020 Authors: Kundinger SR; Bishof I; Dammer EB; Duong DM; Seyfried NT
• Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains.
  Cell Volume: 180 Page(s): 633 - 644.e12
  02/20/2020 Authors: Arakhamia T; Lee CE; Carlomagno Y; Duong DM; Kundinger SR; Wang K; Williams D; DeTure M; Dickson DW; Cook CN
• Quantitative Proteomics Reveal an Altered Pattern of Protein Expression in Brain Tissue from Mice Lacking GPR37 and GPR37L1.
  J Proteome Res Volume: 19 Page(s): 744 - 755
  02/07/2020 Authors: Nguyen TT; Dammer EB; Owino SA; Giddens MM; Madaras NS; Duong DM; Seyfried NT; Hall RA
• Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia.
  NPJ Genom Med Volume: 5 Page(s): 6
  02/06/2020 Authors: Wingo TS; Yang J; Fan W; Min Canon S; Gerasimov ES; Lori A; Logsdon B; Yao B; Seyfried NT; Lah JJ
• Translational animal models for Alzheimer's disease: An Alzheimer's Association Business Consortium Think Tank.
  Alzheimers Dement (N Y) Volume: 6 Page(s): e12114
  01/01/2020 Authors: Vitek MP; Araujo JA; Fossel M; Greenberg BD; Howell GR; Rizzo SJS; Seyfried NT; Tenner AJ; Territo PR; Windisch M
• Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer's disease.
  Clin Proteomics Volume: 17 Page(s): 19
  01/01/2020 Authors: Zhou M; Haque RU; Dammer EB; Duong DM; Ping L; Johnson ECB; Lah JJ; Levey AI; Seyfried NT
• Molecular Signatures of Neuroinflammation Induced by Synuclein Aggregates in Microglial Cells.
  Front Immunol Volume: 11 Page(s): 33
  01/01/2020 Authors: Sarkar S; Dammer EB; Malovic E; Olsen AL; Raza SA; Gao T; Xiao H; Oliver DL; Duong D; Joers V
• Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia.
  NPJ Genom Med Volume: 5 Page(s): 6
  01/01/2020 Authors: Wingo TS; Yang J; Fan W; Min Canon S; Gerasimov ES; Lori A; Logsdon B; Yao B; Seyfried NT; Lah JJ
• Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease.
  Cell Rep Volume: 29 Page(s): 301 - 316.e10
  10/08/2019 Authors: Hsieh Y-C; Guo C; Yalamanchili HK; Abreha M; Al-Ouran R; Li Y; Dammer EB; Lah JJ; Levey AI; Bennett DA
• Transcriptional regulation of homeostatic and disease-associated-microglial genes by IRF1, LXR, and CEBP.
  Glia Volume: 67 Page(s): 1958 - 1975
  10/01/2019 Authors: Gao T; Jernigan J; Raza SA; Dammer EB; Xiao H; Seyfried NT; Levey AI; Rangaraju S
• A Consensus Alzheimer's Disease Brain Protein Co-Expression Network Identifies Robust Biological Alterations Associated with Early- And Late-Stage Disease
  Volume: 86 Page(s): S242 - S242
  10/01/2019 Authors: Johnson ECB; Dammer EB; Duong DM; Yin L; Betarbet R; Shulman JM; Lah JJ; Levey AI; Seyfried NT
• Quantitative Proteomics of Mouse CSF Identifies Novel Human-Relevant Biomarkers of Alzheimer's Disease Pathology
  Volume: 86 Page(s): S149 - S150
  10/01/2019 Authors: Rangaraju S; Rayaprolu S; Cheng L; Ramesha S; Gao T; Xiao H; Duc D; Levey AI; Seyfried NT
• Ionizing Radiation induction of cholesterol biosynthesis in Lung tissue.
  Sci Rep Volume: 9 Page(s): 12546
  08/29/2019 Authors: Werner E; Alter A; Deng Q; Dammer EB; Wang Y; Yu DS; Duong DM; Seyfried NT; Doetsch PW
• Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer's Disease.
  Proteomes Volume: 7
  08/01/2019 Authors: Higginbotham L; Dammer EB; Duong DM; Modeste E; Montine TJ; Lah JJ; Levey AI; Seyfried NT
• hnRNPUL1 regulation by ATR in DNA damage response
  Volume: 79
  07/01/2019 Authors: Zhang H; Head PE; Duong DM; Seyfried NT; Yu DS
• DNA-PKCS deacetylation by SIRT2 promotes DNA double-strand break repair by non-homologous end joining
  CANCER RESEARCH Volume: 79
  07/01/2019 Authors: Head PE; Ganji NP; Wang S-Y; Duong D; Zhang H; Daddacha W; Li S; Seyfried NT; Smalley DM; Wang Y
• Specific Proteomes of Hippocampal Regions CA2 and CA1 Reveal Proteins Linked to the Unique Physiology of Area CA2.
  J Proteome Res Volume: 18 Page(s): 2571 - 2584
  06/07/2019 Authors: Gerber KJ; Dammer EB; Duong DM; Deng Q; Dudek SM; Seyfried NT; Hepler JR
• Mass Spectrometry-Based Quantification of Tau in Human Cerebrospinal Fluid Using a Complementary Tryptic Peptide Standard.
  J Proteome Res Volume: 18 Page(s): 2422 - 2432
  06/07/2019 Authors: Zhou M; Duong DM; Johnson ECB; Dai J; Lah JJ; Levey AI; Seyfried NT
• Dementia in ALS: the role of the cerebellum
  Volume: 78 Page(s): 520 - 521
  06/01/2019 Authors: Lowder L; Asress S; Dammer E; Vizcarra JC; Duc D; Goodman A; Bagchi P; Gearing M; Gutman D; Seyfried N
• Human Brain Proteome-Wide Association Study of Longitudinally Assessed Late-Life Depression
  Volume: 85 Page(s): S249 - S249
  05/15/2019 Authors: Wingo A; Fan W; Seyfried N; Duc D; Dammer E; Bennett D; Lah J; Levey A; Wingo T
• Proteomic analysis reveals that wildtype and alanine-expanded nuclear poly(A)-binding protein exhibit differential interactions in skeletal muscle.
  J Biol Chem Volume: 294 Page(s): 7360 - 7376
  05/03/2019 Authors: Banerjee A; Phillips BL; Deng Q; Seyfried NT; Pavlath GK; Vest KE; Corbett AH
• Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior.
  J Neurosci Volume: 39 Page(s): 3561 - 3581
  05/01/2019 Authors: Gokhale A; Hartwig C; Freeman AAH; Bassell JL; Zlatic SA; Sapp Savas C; Vadlamudi T; Abudulai F; Pham TT; Crocker A
• Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age.
  Nat Commun Volume: 10 Page(s): 1619
  04/08/2019 Authors: Wingo AP; Dammer EB; Breen MS; Logsdon BA; Duong DM; Troncosco JC; Thambisetty M; Beach TG; Serrano GE; Reiman EM
• Proteomic analysis of the poly-ubiquitin profiles in Alzheimer's Disease
  Volume: 33
  04/01/2019 Authors: Zhang TT; Dammer EB; Abreha M; Duong DM; Lah JJ; Levey AI; Seyfried NT
• Characterizing a Novel RGS14:MyosinV/VI Interaction in Brain
  Volume: 33
  04/01/2019 Authors: Montanez-Miranda C; Evans PR; Gerber KJ; Seyfried NT; Hepler JR
• MRE11 Regulation by SIRT2 in DNA Double-Strand Break Repair
  Volume: 33
  04/01/2019 Authors: Zhang H; Head PS; Bastien A; Li C; Duc D; Seyfried N; Yu D
• Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.
  Nat Med Volume: 25 Page(s): 152 - 164
  01/01/2019 Authors: Swarup V; Hinz FI; Rexach JE; Noguchi K-I; Toyoshiba H; Oda A; Hirai K; Sarkar A; Seyfried NT; Cheng C
• Deciphering the glyco(phospho)peptide code of symptomatic Alzheimer's Disease
  Volume: 28 Page(s): 1063 - 1063
  12/01/2018 Authors: Dutta S; Jones MB; Matsumoto Y; Heimburg-Molinaro J; Seyfried N; Cummings R
• Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression.
  Transl Psychiatry Volume: 8 Page(s): 245
  11/08/2018 Authors: Srikanth P; Lagomarsino VN; Pearse RV; Liao M; Ghosh S; Nehme R; Seyfried N; Eggan K; Young-Pearse TL
• Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease.
  Mol Neurodegener Volume: 13 Page(s): 52
  10/04/2018 Authors: Johnson ECB; Dammer EB; Duong DM; Yin L; Thambisetty M; Troncoso JC; Lah JJ; Levey AI; Seyfried NT
• Quantitative Proteomics of CSF and Plasma Reveals Candidate Biomarkers Linked to Immune-Related Pathways in Alzheimer's Disease
  Volume: 84 Page(s): S64 - S65
  10/01/2018 Authors: Duong DM; Lah JJ; Levey AI; Seyfried NT
• Proteomic Changes in Frontotemporal Lobar Degeneration Due to Microtubule Associated Protein Tau (MAPT) Mutations
  Volume: 84 Page(s): S161 - S161
  10/01/2018 Authors: Hales C; Duc D; Seyfried N; Webster J; Levey A; Lah J; Dammer E
• Quantitative Proteomics of the Human Brain Reveals Proteins Associated with Cognitive Resilience
  ANNALS OF NEUROLOGY Volume: 84 Page(s): S62 - S62
  10/01/2018 Authors: Wingo AP; Dammer EB; Duc D; Breen M; Logsdon B; Yang J; Beach TG; Reiman E; Thambisetty M; Troncosco J
• Comprehensive Mapping of Alzheimer's Disease Brain Ubiquitin Pattern Revealed Novel Tau Ubiquitylation Sites
  Volume: 84 Page(s): S65 - S65
  10/01/2018 Authors: Abreha M; Dammer E; Ping L; Duc D; Gearing M; Lah J; Levey A; Seyfried N
• Effects of APOE Genotype on Protein Co-Expression in Alzheimer's Disease
  Volume: 84 Page(s): S164 - S164
  10/01/2018 Authors: Dammer EB; Dai J; Johnson ECB; Duong DM; Gearing M; Lah JJ; Levey AI; Wingo TS; Seyfried NT
• Establishing a Roadmap for Brain-Based Protein Biomarkers in Alzheimer's Disease
  Volume: 84 Page(s): S165 - S166
  10/01/2018 Authors: Zhou M; Duong DM; Ping L; Dammer EB; Gearing M; Lah JJ; Levey AI; Seyfried NT
• Deep Proteomic Network Analysis of AD Brain Reveals Alterations in RNA Binding Proteins and RNA Splicing Associated with Disease
  Volume: 84 Page(s): S68 - S68
  10/01/2018 Authors: Johnson E; Dammer E; Duc D; Thambisetty M; Troncoso J; Lah J; Levey A; Seyfried N
• The Role of the Inflammation Module Hub Protein Moesin in AD
  Volume: 84 Page(s): S160 - S160
  10/01/2018 Authors: Betarbet R; Raza SA; Webster J; Eric DB; Duong D; Seyfried NT; Levey AI; Rangaraju S; Lah JJ
• Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease.
  Proteomics Volume: 18 Page(s): e1800108
  10/01/2018 Authors: Abreha MH; Dammer EB; Ping L; Zhang T; Duong DM; Gearing M; Lah JJ; Levey AI; Seyfried NT
• The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.
  Sci Data Volume: 5 Page(s): 180185
  09/11/2018 Authors: Wang M; Beckmann ND; Roussos P; Wang E; Zhou X; Wang Q; Ming C; Neff R; Ma W; Fullard JF
• RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.
  J Biol Chem Volume: 293 Page(s): 11047 - 11066
  07/13/2018 Authors: Bishof I; Dammer EB; Duong DM; Kundinger SR; Gearing M; Lah JJ; Levey AI; Seyfried NT
• Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins.
  Mol Neurodegener Volume: 13 Page(s): 34
  06/28/2018 Authors: Rangaraju S; Dammer EB; Raza SA; Gao T; Xiao H; Betarbet R; Duong DM; Webster JA; Hales CM; Lah JJ
• Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease.
  Mol Neurodegener Volume: 13 Page(s): 24
  05/21/2018 Authors: Rangaraju S; Dammer EB; Raza SA; Rathakrishnan P; Xiao H; Gao T; Duong DM; Pennington MW; Lah JJ; Seyfried NT
• Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.
  J Proteome Res Volume: 17 Page(s): 1700 - 1711
  04/06/2018 Authors: Evans PR; Gerber KJ; Dammer EB; Duong DM; Goswami D; Lustberg DJ; Zou J; Yang JJ; Dudek SM; Griffin PR
• Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease.
  Sci Data Volume: 5 Page(s): 180036
  03/13/2018 Authors: Ping L; Duong DM; Yin L; Gearing M; Lah JJ; Levey AI; Seyfried NT
• Evidence for brain glucose dysregulation in Alzheimer's disease.
  Alzheimers Dement Volume: 14 Page(s): 318 - 329
  03/01/2018 Authors: An Y; Varma VR; Varma S; Casanova R; Dammer E; Pletnikova O; Chia CW; Egan JM; Ferrucci L; Troncoso J
• Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases.
  Alzheimers Dement Volume: 14 Page(s): 352 - 366
  03/01/2018 Authors: Allen M; Wang X; Burgess JD; Watzlawik J; Serie DJ; Younkin CS; Nguyen T; Malphrus KG; Lincoln S; Carrasquillo MM
• TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD.
  Nat Neurosci Volume: 21 Page(s): 228 - 239
  02/01/2018 Authors: Chou C-C; Zhang Y; Umoh ME; Vaughan SW; Lorenzini I; Liu F; Sayegh M; Donlin-Asp PG; Chen YH; Duong DM
• Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy.
  J Neuropathol Exp Neurol Volume: 77 Page(s): 40 - 49
  01/01/2018 Authors: Cherry JD; Zeineddin A; Dammer EB; Webster JA; Duong D; Seyfried NT; Levey AI; Alvarez VE; Huber BR; Stein TD
• A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain.
  EMBO Mol Med Volume: 10 Page(s): 48 - 62
  01/01/2018 Authors: Umoh ME; Dammer EB; Dai J; Duong DM; Lah JJ; Levey AI; Gearing M; Glass JD; Seyfried NT
• Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer.
  Sci Adv Volume: 4 Page(s): e1701393
  01/01/2018 Authors: Bhuripanyo K; Wang Y; Liu X; Zhou L; Liu R; Duong D; Zhao B; Bi Y; Zhou H; Chen G
• Differential Phagocytic Properties of CD45low Microglia and CD45high Brain Mononuclear Phagocytes-Activation and Age-Related Effects.
  Front Immunol Volume: 9 Page(s): 405
  01/01/2018 Authors: Rangaraju S; Raza SA; Li NX; Betarbet R; Dammer EB; Duong D; Lah JJ; Seyfried NT; Levey AI
• Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease.
  Front Mol Neurosci Volume: 11 Page(s): 454
  01/01/2018 Authors: Dai J; Johnson ECB; Dammer EB; Duong DM; Gearing M; Lah JJ; Levey AI; Wingo TS; Seyfried NT
• Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease.
  Mol Neurodegener Volume: 12 Page(s): 82
  11/06/2017 Authors: McKenzie AT; Moyon S; Wang M; Katsyv I; Song W-M; Zhou X; Dammer EB; Duong DM; Aaker J; Zhao Y
• Enrichment of Detergent-insoluble Protein Aggregates from Human Postmortem Brain.
  J Vis Exp
  10/24/2017 Authors: Diner I; Nguyen T; Seyfried NT
• Generation of Clickable Pittsburgh Compound B for the Detection and Capture of -Amyloid in Alzheimer's Disease Brain.
  Bioconjug Chem Volume: 28 Page(s): 2627 - 2637
  10/18/2017 Authors: Diner I; Dooyema J; Gearing M; Walker LC; Seyfried NT
• Systems Pharmacology Approach to Identify Novel Kv1.3 Channel Dependent Mechanisms in Microglial Activation
  Volume: 82 Page(s): S30 - S30
  10/01/2017 Authors: Raza SA; Deng Q; Dammer EB; Duong D; Tansey MG; Lah JJ; Betarbet R; Seyfried NT; Levey AI; Rangaraju S
• The RNA-binding protein, ZC3H14, is required for proper poly(A) tail length control, expression of synaptic proteins, and brain function in mice.
  Hum Mol Genet Volume: 26 Page(s): 3663 - 3681
  10/01/2017 Authors: Rha J; Jones SK; Fidler J; Banerjee A; Leung SW; Morris KJ; Wong JC; Inglis GAS; Shapiro L; Deng Q
• Integrating Next-Generation Genomic Sequencing and Mass Spectrometry To Estimate Allele-Specific Protein Abundance in Human Brain.
  J Proteome Res Volume: 16 Page(s): 3336 - 3347
  09/01/2017 Authors: Wingo TS; Duong DM; Zhou M; Dammer EB; Wu H; Cutler DJ; Lah JJ; Levey AI; Seyfried NT
• Biochemical isolation of myonuclei employed to define changes to the myonuclear proteome that occur with aging.
  Aging Cell Volume: 16 Page(s): 738 - 749
  08/01/2017 Authors: Cutler AA; Dammer EB; Doung DM; Seyfried NT; Corbett AH; Pavlath GK
• Asparagine endopeptidase cleaves -synuclein and mediates pathologic activities in Parkinson's disease.
  Nat Struct Mol Biol Volume: 24 Page(s): 632 - 642
  08/01/2017 Authors: Zhang Z; Kang SS; Liu X; Ahn EH; Zhang Z; He L; Iuvone PM; Duong DM; Seyfried NT; Benskey MJ
• Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF).
  J Biol Chem Volume: 292 Page(s): 11091 - 11108
  06/30/2017 Authors: Ivanova AA; Caspary T; Seyfried NT; Duong DM; West AB; Liu Z; Kahn RA
• A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation.
  J Neuroinflammation Volume: 14 Page(s): 128
  06/26/2017 Authors: Rangaraju S; Raza SA; Pennati A; Deng Q; Dammer EB; Duong D; Pennington MW; Tansey MG; Lah JJ; Betarbet R
• Comparison of detergent-insoluble proteome changes in autosomal dominant Alzheimer's disease brain to late onset AD and transgenic rodents
  Volume: 88
  04/18/2017 Authors: Hales C; Dammer E; Duong D; Gearing M; Cohen R; Wingo T; Lah J; Levey A; Seyfried N
• A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease.
  Cell Syst Volume: 4 Page(s): 60 - 72.e4
  01/25/2017 Authors: Seyfried NT; Dammer EB; Swarup V; Nandakumar D; Duong DM; Yin L; Deng Q; Nguyen T; Hales CM; Wingo T
• The State of Systems Genetics in 2017.
  Cell Syst Volume: 4 Page(s): 7 - 15
  01/25/2017 Authors: Baliga NS; Bjrkegren JLM; Boeke JD; Boutros M; Crawford NPS; Dudley AM; Farber CR; Jones A; Levey AI; Lusis AJ
• Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway.
  Mol Psychiatry Volume: 22 Page(s): 13 - 23
  01/01/2017 Authors: Varma VR; Varma S; An Y; Hohman TJ; Seddighi S; Casanova R; Beri A; Dammer EB; Seyfried NT; Pletnikova O
• Osteopontin Is a Blood Biomarker for Microglial Activation and Brain Injury in Experimental Hypoxic-Ischemic Encephalopathy.
  eNeuro Volume: 4
  01/01/2017 Authors: Li Y; Dammer EB; Zhang-Brotzge X; Chen S; Duong DM; Seyfried NT; Kuan C-Y; Sun Y-Y
• Cellular O-glycome Reporter/Amplification to explore O-glycans of living cells
  Volume: 26 Page(s): 1454 - 1454
  12/01/2016 Authors: Kudelka MR; Antonopoulos A; Wang Y; Duong DM; Song X; Seyfried NT; Dell A; Haslam SM; Cummings RD; Ju T
• Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression.
  Proteomics Volume: 16 Page(s): 3042 - 3053
  12/01/2016 Authors: Hales CM; Dammer EB; Deng Q; Duong DM; Gearing M; Troncoso JC; Thambisetty M; Lah JJ; Shulman JM; Levey AI
• The Evolutionarily-conserved Polyadenosine RNA Binding Protein, Nab2, Cooperates with Splicing Machinery to Regulate the Fate of pre-mRNA.
  Mol Cell Biol Volume: 36 Page(s): 2697 - 2714
  11/01/2016 Authors: Soucek S; Zeng Y; Bellur DL; Bergkessel M; Morris KJ; Deng Q; Duong D; Seyfried NT; Guthrie C; Staley JP
• NADPH Dehydrogenase Quinone 1 (NQO1) Demonstrates Increased Expression and Pathologic Aggregation in Glial Cells in Chronic Traumatic Encephalopathy
  Volume: 80 Page(s): S195 - S195
  10/01/2016 Authors: Hales C; Zeineddin A; Webster J; Giuliano J; Duong D; Seyfried N; Dammer E; Mckee A; Levey A; Lah J
• SUMO Modification of the Base Excision Repair Protein, Ntg1, Links DNA Damage and DNA Damage Response.
  Volume: 57 Page(s): S59 - S59
  09/01/2016 Authors: McPherson AJ; Swartzlander DB; Limpose KL; Duong D; Seyfried NT; Doetsch PW; Corbett AH
• Genealogical Inference of Cellular and Molecular Mechanisms Downstream of the Chromosome 22q11.2 Microdeletion
  Volume: 79 Page(s): 42S - 43S
  05/01/2016 Authors: Gokhale A; Freeman A; Zlatic SA; Hartwig C; Comstra SH; Duong D; Espinoza K; Seyfried N; Repetto G; Diamantopoulou A
• A Comparative Analysis of the Insoluble Brain Proteome in Alzheimer's Disease, Chronic Traumatic Encephalopathy and Frontotemporal Dementia
  Volume: 86
  04/05/2016 Authors: Hales C; Dammer E; Duong D; Webster J; Zeineddin A; Seyfried N; Lah J
• Differential Gene Expression in Microglial Polarized States and in Alzheimer's Disease: Novel Insights Provided by Weighted Correlation Network Analysis (WGCNA)
  Volume: 86
  04/05/2016 Authors: Rangaraju S; Dammer E; Seyfried N; Levey A
• Differential Gene Expression in Microglial Polarized States and in Alzheimers Disease: Novel Insights Provided by Weighted Correlation Network Analysis (WGCNA)
  Volume: 86
  04/05/2016 Authors: Rangaraju S; Dammer E; Seyfried N; Levey A
• A Comparative Analysis of the Insoluble Brain Proteome in Alzheimer's Disease, Chronic Traumatic Encephalopathy and Frontotemporal Dementia
  Volume: 86
  04/05/2016 Authors: Hales C; Dammer E; Duc D; Webster J; Zeineddin A; Seyfried N; Lah J
• Cellular O-Glycome Reporter/Amplification (CORA) to Explore O-Glycans of Living Cells
  Volume: 30
  04/01/2016 Authors: Kudelka MR; Antonopoulos A; Wang Y; Duong DM; Song X; Seyfried NT; Dell A; Haslam SM; Cummings RD; Ju T
• CSF complement 3 and factor H are staging biomarkers in Alzheimer's disease.
  Acta Neuropathol Commun Volume: 4 Page(s): 14
  02/17/2016 Authors: Hu WT; Watts KD; Tailor P; Nguyen TP; Howell JC; Lee RC; Seyfried NT; Gearing M; Hales CM; Levey AI
• ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA.
  Cell Rep Volume: 14 Page(s): 1435 - 1447
  02/16/2016 Authors: Zhang H; Head PE; Daddacha W; Park S-H; Li X; Pan Y; Madden MZ; Duong DM; Xie M; Yu B
• Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase.
  J Biol Chem Volume: 291 Page(s): 3280 - 3290
  02/12/2016 Authors: Owings JP; Kuiper EG; Prezioso SM; Meisner J; Varga JJ; Zelinskaya N; Dammer EB; Duong DM; Seyfried NT; Albert S
• Cellular O-Glycome Reporter/Amplification to explore O-glycans of living cells.
  Nat Methods Volume: 13 Page(s): 81 - 86
  01/01/2016 Authors: Kudelka MR; Antonopoulos A; Wang Y; Duong DM; Song X; Seyfried NT; Dell A; Haslam SM; Cummings RD; Ju T
• Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease.
  Nat Commun Volume: 6 Page(s): 8762
  11/09/2015 Authors: Zhang Z; Song M; Liu X; Su Kang S; Duong DM; Seyfried NT; Cao X; Cheng L; Sun YE; Ping Yu S
• SUMO Modification of the Base Excision Repair Protein, Ntg1, Links DNA Damage and DNA Damage Response
  ENVIRONMENTAL AND MOLECULAR MUTAGENESIS Volume: 56 Page(s): S66 - S66
  08/01/2015 Authors: McPherson AJ; Swartzlander DB; Bauer NC; Limpose KL; Duong D; Seyfried N; Doetsch PW; Corbett AH
• An Intrinsically Disordered Low Complexity Domain is Required for U1-70K Self-association
  Volume: 29
  04/01/2015 Authors: Bishof I; Diner I; Seyfried N
• Tau phosphosignatures discriminate Alzheimer Disease from other tauopathies
  FASEB JOURNAL Volume: 29
  04/01/2015 Authors: Seyfried N; Dammer E; Ren R; Gearing M; Duc D; Lah J; Levey A
• Consequences of impaired purine recycling on the proteome in a cellular model of Lesch-Nyhan disease.
  Mol Genet Metab Volume: 114 Page(s): 570 - 579
  04/01/2015 Authors: Dammer EB; Gttle M; Duong DM; Hanfelt J; Seyfried NT; Jinnah HA
• Stress induces p38 MAPK-mediated phosphorylation and inhibition of Drosha-dependent cell survival.
  Mol Cell Volume: 57 Page(s): 721 - 734
  02/19/2015 Authors: Yang Q; Li W; She H; Dou J; Duong DM; Du Y; Yang S-H; Seyfried NT; Fu H; Gao G
• Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth.
  Cancer Cell Volume: 27 Page(s): 257 - 270
  02/09/2015 Authors: Jin L; Li D; Alesi GN; Fan J; Kang H-B; Lu Z; Boggon TJ; Jin P; Yi H; Wright ER
• The Pseudomonas aeruginosa EF-Tu modifying enzyme, EftM, is a temperature-regulated enzyme that aids in adhesion and invasion of host cells
  Volume: 26
  01/01/2015 Authors: Kuiper EG; Owings JP; Prezioso SM; Meisner J; Varga JP; Zelinskaya N; Dammer EB; Duong D; Seyfried N; Alberti S
• Ensuring efficient coupling of pre mRNA processing and nuclear export: A link between the Tho complex and the polyadenosine RNA binding protein, ZC3H14
  Volume: 26
  01/01/2015 Authors: Morris K; Fasken M; Wigington C; Leung SW; Duong D; Seyfried N; Corbett AH
• Characterizing the protein-protein interactions of the polyadenylate binding protein nuclear 1 (PABPN1), the protein mutated in Oculopharyngeal Muscular Dystrophy (OPMD)
  Volume: 26
  01/01/2015 Authors: Banerjee A; Duong D; Seyfried N; Pavlath GK; Corbett AH
• Quantitative phosphoproteomics of Alzheimer's disease reveals cross-talk between kinases and small heat shock proteins.
  Proteomics Volume: 15 Page(s): 508 - 519
  01/01/2015 Authors: Dammer EB; Lee AK; Duong DM; Gearing M; Lah JJ; Levey AI; Seyfried NT
• Aggregation properties of the small nuclear ribonucleoprotein U1-70K in Alzheimer disease.
  J Biol Chem Volume: 289 Page(s): 35296 - 35313
  12/19/2014 Authors: Diner I; Hales CM; Bishof I; Rabenold L; Duong DM; Yi H; Laur O; Gearing M; Troncoso J; Thambisetty M
• Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease.
  Nat Med Volume: 20 Page(s): 1254 - 1262
  11/01/2014 Authors: Zhang Z; Song M; Liu X; Kang SS; Kwon I-S; Duong DM; Seyfried NT; Hu WT; Liu Z; Wang J-Z
• Stress-dependent proteolytic processing of the actin assembly protein Lsb1 modulates a yeast prion.
  J Biol Chem Volume: 289 Page(s): 27625 - 27639
  10/03/2014 Authors: Ali M; Chernova TA; Newnam GP; Yin L; Shanks J; Karpova TS; Lee A; Laur O; Subramanian S; Kim D
• Aggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease.
  Brain Pathol Volume: 24 Page(s): 344 - 351
  07/01/2014 Authors: Hales CM; Dammer EB; Diner I; Yi H; Seyfried NT; Gearing M; Glass JD; Montine TJ; Levey AI; Lah JJ
• FUS is phosphorylated by DNA-PK and accumulates in the cytoplasm after DNA damage.
  J Neurosci Volume: 34 Page(s): 7802 - 7813
  06/04/2014 Authors: Deng Q; Holler CJ; Taylor G; Hudson KF; Watkins W; Gearing M; Ito D; Murray ME; Dickson DW; Seyfried NT
• U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21.
  Mol Neurodegener Volume: 9 Page(s): 15
  04/28/2014 Authors: Hales CM; Seyfried NT; Dammer EB; Duong D; Yi H; Gearing M; Troncoso JC; Mufson EJ; Thambisetty M; Levey AI
• Evaluating the effect of formalin fixation on mass spectrometry-based proteomic profiling
  FASEB JOURNAL Volume: 28
  04/01/2014 Authors: Atwood J; Neumann D; Dammer E; Duong D; Dunn C; Seyfried N
• Proteomics of protein post-translational modifications implicated in neurodegeneration.
  Transl Neurodegener Volume: 3 Page(s): 23
  01/01/2014 Authors: Ren R-J; Dammer EB; Wang G; Seyfried NT; Levey AI
• Pharmacologic inhibition of ROCK2 suppresses amyloid- production in an Alzheimer's disease mouse model.
  J Neurosci Volume: 33 Page(s): 19086 - 19098
  12/04/2013 Authors: Herskowitz JH; Feng Y; Mattheyses AL; Hales CM; Higginbotham LA; Duong DM; Montine TJ; Troncoso JC; Thambisetty M; Seyfried NT
• Tissue-type plasminogen activator mediates neuronal detection and adaptation to metabolic stress.
  J Cereb Blood Flow Metab Volume: 33 Page(s): 1761 - 1769
  11/01/2013 Authors: Wu F; Nicholson AD; Haile WB; Torre E; An J; Chen C; Lee AK; Duong DM; Dammer EB; Seyfried NT
• Abnormal gephyrin immunoreactivity associated with Alzheimer disease pathologic changes.
  J Neuropathol Exp Neurol Volume: 72 Page(s): 1009 - 1015
  11/01/2013 Authors: Hales CM; Rees H; Seyfried NT; Dammer EB; Duong DM; Gearing M; Montine TJ; Troncoso JC; Thambisetty M; Levey AI
• Selective targeting of the cysteine proteome by thioredoxin and glutathione redox systems.
  Mol Cell Proteomics Volume: 12 Page(s): 3285 - 3296
  11/01/2013 Authors: Go Y-M; Roede JR; Walker DI; Duong DM; Seyfried NT; Orr M; Liang Y; Pennell KD; Jones DP
• U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.
  Proc Natl Acad Sci U S A Volume: 110 Page(s): 16562 - 16567
  10/08/2013 Authors: Bai B; Hales CM; Chen P-C; Gozal Y; Dammer EB; Fritz JJ; Wang X; Xia Q; Duong DM; Street C
• SIRT2 directs the replication stress response through CDK9 deacetylation.
  Proc Natl Acad Sci U S A Volume: 110 Page(s): 13546 - 13551
  08/13/2013 Authors: Zhang H; Park S-H; Pantazides BG; Karpiuk O; Warren MD; Hardy CW; Duong DM; Park S-J; Kim H-S; Vassilopoulos A
• Neuron enriched nuclear proteome isolated from human brain.
  J Proteome Res Volume: 12 Page(s): 3193 - 3206
  07/05/2013 Authors: Dammer EB; Duong DM; Diner I; Gearing M; Feng Y; Lah JJ; Levey AI; Seyfried NT
• Expression, purification and proteomic analysis of recombinant histone H4 acetylated at lysine 16.
  Proteomics Volume: 13 Page(s): 1687 - 1691
  05/01/2013 Authors: Kallappagoudar S; Dammer EB; Duong DM; Seyfried NT; Lucchesi JC
• Clinical Tissue Proteomics Identifies the U1 Small Nuclear Ribonucleoprotein Complex in Alzheimer Disease Pathology
  MOLECULAR BIOLOGY OF THE CELL Volume: 24
  01/01/2013 Authors: Chen P-C; Bai B; Hales C; Gozal YM; Li Y; Dammer EB; Cantero G; Seyfried NT; Sun YE; Mufson EJ
• Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease.
  Alzheimers Res Ther Volume: 5 Page(s): 32
  01/01/2013 Authors: Donovan LE; Dammer EB; Duong DM; Hanfelt JJ; Levey AI; Seyfried NT; Lah JJ
• SIRT2 Directs the Replication Stress Response Through CDK9 Deacetylation
  Volume: 84 Page(s): S677 - S677
  11/01/2012 Authors: Zhang H; Park S; Pantazides BG; Hardy CW; Seyfried NT; Duong D; Yu DS
• Asparaginyl endopeptidase cleaves TDP-43 in brain.
  Proteomics Volume: 12 Page(s): 2455 - 2463
  08/01/2012 Authors: Herskowitz JH; Gozal YM; Duong DM; Dammer EB; Gearing M; Ye K; Lah JJ; Peng J; Levey AI; Seyfried NT
• Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain.
  J Neurosci Volume: 32 Page(s): 9848 - 9858
  07/18/2012 Authors: Wu F; Wu J; Nicholson AD; Echeverry R; Haile WB; Catano M; An J; Lee AK; Duong D; Dammer EB
• Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards.
  J Proteome Res Volume: 11 Page(s): 2721 - 2738
  05/04/2012 Authors: Seyfried NT; Gozal YM; Donovan LE; Herskowitz JH; Dammer EB; Xia Q; Ku L; Chang J; Duong DM; Rees HD
• Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease.
  Proteomics Clin Appl Volume: 6 Page(s): 201 - 211
  04/01/2012 Authors: Donovan LE; Higginbotham L; Dammer EB; Gearing M; Rees HD; Xia Q; Duong DM; Seyfried NT; Lah JJ; Levey AI
• Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination.
  PLoS One Volume: 7 Page(s): e38658
  01/01/2012 Authors: Dammer EB; Fallini C; Gozal YM; Duong DM; Rossoll W; Xu P; Lah JJ; Levey AI; Peng J; Bassell GJ
• Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration.
  Mol Neurodegener Volume: 6 Page(s): 82
  11/29/2011 Authors: Gozal YM; Seyfried NT; Gearing M; Glass JD; Heilman CJ; Wuu J; Duong DM; Cheng D; Xia Q; Rees HD
• A novel strategy to isolate ubiquitin conjugates reveals wide role for ubiquitination during neural development.
  Mol Cell Proteomics Volume: 10 Page(s): M110.002188
  05/01/2011 Authors: Franco M; Seyfried NT; Brand AH; Peng J; Mayor U
• Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease.
  J Biol Chem Volume: 286 Page(s): 10457 - 10465
  03/25/2011 Authors: Dammer EB; Na CH; Xu P; Seyfried NT; Duong DM; Cheng D; Gearing M; Rees H; Lah JJ; Levey AI
• Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production.
  J Biol Chem Volume: 286 Page(s): 6117 - 6127
  02/25/2011 Authors: Herskowitz JH; Seyfried NT; Gearing M; Kahn RA; Peng J; Levey AI; Lah JJ
• Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration.
  J Proteome Res Volume: 9 Page(s): 6368 - 6379
  12/03/2010 Authors: Herskowitz JH; Seyfried NT; Duong DM; Xia Q; Rees HD; Gearing M; Peng J; Lah JJ; Levey AI
• A novel strategy to isolate neuronal ubiquitin conjugates reveals a wide role for ubiquitination in synaptogenesis
  JOURNAL OF NEUROGENETICS Volume: 24 Page(s): 38 - 38
  12/01/2010 Authors: Franco M; Seyfried NT; Brand AH; Peng J; Mayor U
• Multiplex SILAC analysis of a cellular TDP-43 proteinopathy model reveals protein inclusions associated with SUMOylation and diverse polyubiquitin chains.
  Mol Cell Proteomics Volume: 9 Page(s): 705 - 718
  04/01/2010 Authors: Seyfried NT; Gozal YM; Dammer EB; Xia Q; Duong DM; Cheng D; Lah JJ; Levey AI; Peng J
• Quantitative proteomics of ubiquitin pathways
  AMINO ACIDS Volume: 37 Page(s): 118 - 118
  07/01/2009 Authors: Xu P; Seyfried NT; Duong DM; Cheng D; Peng J
• Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation.
  Cell Volume: 137 Page(s): 133 - 145
  04/03/2009 Authors: Xu P; Duong DM; Seyfried NT; Cheng D; Xie Y; Robert J; Rush J; Hochstrasser M; Finley D; Peng J
• Systematic approach for validating the ubiquitinated proteome.
  Anal Chem Volume: 80 Page(s): 4161 - 4169
  06/01/2008 Authors: Seyfried NT; Xu P; Duong DM; Cheng D; Hanfelt J; Peng J
• Up-regulation of NG2 proteoglycan and interferon-induced transmembrane proteins 1 and 3 in mouse astrocytoma: a membrane proteomics approach.
  Cancer Lett Volume: 263 Page(s): 243 - 252
  05/18/2008 Authors: Seyfried NT; Huysentruyt LC; Atwood JA; Xia Q; Seyfried TN; Orlando R
• Determination of protein-RNA interaction sites in the Cbf5-H/ACA guide RNA complex by mass spectrometric protein footprinting.
  Biochemistry Volume: 47 Page(s): 1500 - 1510
  02/12/2008 Authors: Baker DL; Seyfried NT; Li H; Orlando R; Terns RM; Terns MP
• Expression and functional characterization of the G1 domain from human versican
  Volume: 88 Page(s): A85 - A85
  12/01/2007 Authors: Fielder HL; Seyfried NT; Noble M; Day AJ
• Fourier transform mass spectrometry to monitor hyaluronan-protein interactions: use of hydrogen/deuterium amide exchange.
  Rapid Commun Mass Spectrom Volume: 21 Page(s): 121 - 131
  01/01/2007 Authors: Seyfried NT; Atwood JA; Yongye A; Almond A; Day AJ; Orlando R; Woods RJ
• Versican-thrombospondin-1 binding in vitro and colocalization in microfibrils induced by inflammation on vascular smooth muscle cells.
  J Cell Sci Volume: 119 Page(s): 4499 - 4509
  11/01/2006 Authors: Kuznetsova SA; Issa P; Perruccio EM; Zeng B; Sipes JM; Ward Y; Seyfried NT; Fielder HL; Day AJ; Wight TN
• Induction of versican-thrombospondin-1 complexes during endoplasmic reticulum stress on vascular smooth muscle cells
  Volume: 20 Page(s): A516 - A516
  03/06/2006 Authors: Kuznetsova SA; Issa P; Perruccio EM; Zeng BX; Seyfried NT; Fielder HL; Day AJ; Wight TN; Roberts DD
• Experimental evidence for all-or-none cooperative interactions between the G1-domain of versican and multivalent hyaluronan oligosaccharides.
  Matrix Biol Volume: 25 Page(s): 14 - 19
  01/01/2006 Authors: Seyfried NT; Day AJ; Almond A
• Experimental evidence for all-or-none cooperative interactions between the G1-domain of versican and multivalent hyaluronan oligosaccharides
  Volume: 15 Page(s): 1213 - 1214
  11/01/2005 Authors: Seyfried NT; Day AJ; Almond A
• Preparation and application of biologically active fluorescent hyaluronan oligosaccharides.
  Glycobiology Volume: 15 Page(s): 303 - 312
  03/01/2005 Authors: Seyfried NT; Blundell CD; Day AJ; Almond A
• Expression and purification of functionally active hyaluronan-binding domains from human cartilage link protein, aggrecan and versican: formation of ternary complexes with defined hyaluronan oligosaccharides.
  J Biol Chem Volume: 280 Page(s): 5435 - 5448
  02/18/2005 Authors: Seyfried NT; McVey GF; Almond A; Mahoney DJ; Dudhia J; Day AJ
• British Society for Matrix Biology meeting. Manchester, 5-6 april 2004. Abstracts.
  Int J Exp Pathol Volume: 85 Page(s): A45 - A77
  10/01/2004 Authors: Jones GC; Seyfried NT; Bastow ER
• Structural and functional studies on hyaluronan-protein aggregates produced in vitro
  Volume: 85 Page(s): A74 - A75
  08/01/2004 Authors: Seyfried NT; McVey GF; Dudhia J; Day AJ
• Continuous release of endostatin from microencapsulated engineered cells for tumor therapy.
  Nat Biotechnol Volume: 19 Page(s): 35 - 39
  01/01/2001 Authors: Joki T; Machluf M; Atala A; Zhu J; Seyfried NT; Dunn IF; Abe T; Carroll RS; Black PM
• Expression of cyclooxygenase 2 (COX-2) in human glioma and in vitro inhibition by a specific COX-2 inhibitor, NS-398.
  Cancer Res Volume: 60 Page(s): 4926 - 4931
  09/01/2000 Authors: Joki T; Heese O; Nikas DC; Bello L; Zhang J; Kraeft SK; Seyfried NT; Abe T; Chen LB; Carroll RS