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Profile

Nadine Rouphael MD

  • Department of Medicine
    Professor
  • (404) 712-1435
  • nroupha@emory.edu
Head shot of Nadine Rouphael

Overview

Dr. Nadine Rouphael (MD) is the Sumner E. Thompson, III Distinguished Professor of Vaccinology and Infectious Diseases at Emory University in Atlanta, USA. She graduated from Saint Joseph University School of Medicine in Lebanon (2001). She completed her internal medicine residency (2005) and infectious diseases fellowship (2008) at Emory University. She serves as the executive director of the Hope Clinic, the clinical arm of the Emory Vaccine Center and the Emory principal investigator for the NIH funded Vaccine Treatment and Evaluation Unit (VTEU) and the co Clinical Core principal investigator for NIH funded Stanford Human Immunology Project Consortium (HIPC). She has served as the national chair/co-chair as well as overall PI/site PI of 75 clinical studies and an investigator on more than 200 studies. She has interest in antimicrobial resistance, vaccine clinical trials (pandemic influenza, Zika, Ebola, SARS-CoV2), vaccine delivery methods (NIH funded phase 1 trial on microneedle influenza vaccine patch where a first in human dissolvable patch was shown to be safe, immunogenic and preferred to the traditional needle and syringe), translational research on innate immunity and systems biology (using vaccines as way to probe the immune system and one of the first to show an association between antibiotic use and decrease immunogenicity), immune aging and correlates of protection. She has published more than 180 peer reviewed publications and has received many awards. She is currently the associate editor for Clinical Infectious Diseases for the Vaccine section. She is passionate about mentoring the next generation of physician scientists and serves as Co-Director of the Stimulating Access to Research in Residency (StARR) R38 Program and the Director of the T32 vaccinology grant.

Academic Appointment

  • Sumner E. Thompson, III Distinguished Professor of Vaccinology and Infectious Diseases, Emory University School of Medicine
  • Tenured Professor of Medicine, Emory University School of Medicine
  • Professor of Medicine, Emory University School of Medicine
  • Senior Physician, Emory University School of Medicine
  • Investigator, Hope Clinic of the Emory Vaccine Center

Education

Degrees

  • M.S. from Jean Moulin University
  • M.S. from Saint Joseph University School of Medicine
  • M.D. from Saint Joseph University School of Medicine

Research

Focus

  • Vaccine Clinical Trials

    My research focuses on: 1) Correlates of protection for encapsulated bacteria 2) Innate immunity to vaccines through system biology approaches 3) Immune senescence 4) Novel methods for vaccine delivery and human challenges

Publications

  • Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine.
    Cell Host Microbe Volume: 33 Page(s): 705 - 718.e5
    05/14/2025 Authors: Feng Y; de Jong SE; Oliveira APBN; Samaha H; Yang F; Hu M; Wang Y; Beydoun N; Xie X; Zhang H
  • Evaluating the Test-Negative Design for COVID-19 Vaccine Effectiveness Using Randomized Trial Data: A Secondary Cross-Protocol Analysis of 5 Randomized Clinical Trials.
    JAMA Netw Open Volume: 8 Page(s): e2512763
    05/01/2025 Authors: Andrews LIB; Halloran ME; Neuzil KM; van der Laan L; Huang Y; Andriesen J; Patel M; Fisher LH; Janes H; Rouphael N
  • A phase I study of the safety, reactogenicity and immunogenicity of two quadrivalent seasonal influenza vaccines (Fluzone or Flublok) with or without one of two adjuvants (AF03 or Advax-CpG55.2) in healthy adults 18-45years of age.
    Vaccine Volume: 54 Page(s): 126991
    04/30/2025 Authors: Hegmann TE; Walter EB; Smith MJ; Campbell J; El Sahly HM; Whitaker JA; Creech CB; Ustyugova IV; Goncalvez AP; Pandey A
  • Altered baseline immunological state and impaired immune response to SARS-CoV-2 mRNA vaccination in lung transplant recipients.
    Cell Rep Med Volume: 6 Page(s): 102050
    04/15/2025 Authors: Hu M; Oliveira APBN; Fang Z; Feng Y; Miranda M; Kowli S; Arunachalam PS; Vasudevan G; Hui HS-Y; Grifoni A
  • Fgl2 regulates FcRIIB+CD8+ T cell responses during infection.
    JCI Insight Volume: 10
    04/08/2025 Authors: Morris AB; Adelman MW; Bennion KB; Martinez CD; McCook K-M; Woodworth MH; Langelier CR; Rouphael N; Scharer CD; Maier CL
  • Efficacy and Durability of Immune Response After Receipt of Hepatitis A Vaccine in People With Human Immunodeficiency Virus.
    Open Forum Infect Dis Volume: 12 Page(s): ofaf143
    04/01/2025 Authors: Kazzi B; Naji A; Dib SM; Khalil L; Tandon Wimalasana S; Saint-Victor D; Ofotokun I; Rouphael N
  • The KP.2-adapted COVID-19 vaccine improves neutralising activity against the XEC variant.
    Lancet Infect Dis Volume: 25 Page(s): e122 - e123
    03/01/2025 Authors: Suthar MS; Manning KE; Ellis ML; Jain S; Bechnak K; Vander Velden J; Laboune F; Henry AR; Godbole S; Kim S
  • Transcriptomic Biomarkers Associated With Microbiological Etiology and Disease Severity in Childhood Pneumonia.
    J Infect Dis Volume: 231 Page(s): e277 - e289
    02/20/2025 Authors: Williams DJ; Gautam S; Creech CB; Jimenez N; Anderson EJ; Bosinger SE; Grimes T; Arnold SR; McCullers JA; Goll J
  • Anti-neuraminidase and anti-hemagglutinin stalk responses to different influenza a(H7N9) vaccine regimens.
    Vaccine Volume: 47 Page(s): 126689
    02/15/2025 Authors: El Sahly HM; Anderson EJ; Jackson LA; Neuzil KM; Atmar RL; Bernstein DI; Chen WH; Creech CB; Frey SE; Goepfert P
  • Neutralizing Antibody Immune Correlates for a Recombinant Protein Vaccine in the COVAIL Trial.
    Clin Infect Dis Volume: 80 Page(s): 223 - 227
    02/05/2025 Authors: Fong Y; Dang L; Zhang B; Fintzi J; Chen S; Wang J; Rouphael NG; Branche AR; Diemert DJ; Falsey AR
  • Neutralizing antibody immune correlates in COVAIL trial recipients of an mRNA second COVID-19 vaccine boost.
    Nat Commun Volume: 16 Page(s): 759
    01/17/2025 Authors: Zhang B; Fong Y; Dang L; Fintzi J; Chen S; Wang J; Rouphael NG; Branche AR; Diemert DJ; Falsey AR
  • Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients.
    Nat Commun Volume: 16 Page(s): 586
    01/10/2025 Authors: Pickering H; Schaenman J; Phan HV; Maguire C; Tsitsiklis A; Rouphael N; Higuita NIA; Atkinson MA; Brakenridge S; Fung M
  • System vaccinology analysis of predictors and mechanisms of antibody response durability to multiple vaccines in humans.
    Nat Immunol Volume: 26 Page(s): 116 - 130
    01/01/2025 Authors: Cortese M; Hagan T; Rouphael N; Wu S-Y; Xie X; Kazmin D; Wimmers F; Gupta S; van der Most R; Coccia M
  • A Phase 1 randomized trial of homologous and heterologous filovirus vaccines with a late booster dose.
    NPJ Vaccines Volume: 9 Page(s): 255
    12/23/2024 Authors: Rostad CA; Yildirim I; Kao C; Yi J; Kamidani S; Peters E; Stephens K; Gibson T; Hsiao H-M; Singh K
  • Influenza virus infection and aerosol shedding kinetics in a controlled human infection model.
    J Virol Volume: 98 Page(s): e0161224
    12/17/2024 Authors: Shetty N; Shephard MJ; Rockey NC; Macenczak H; Traenkner J; Danzy S; Vargas-Maldonado N; Arts PJ; Le Sage V; Anderson EJ
  • Systems Vaccinology: Navigating the Future of Personalized Immunity and Next-Generation Vaccines.
    J Infect Dis Volume: 230 Page(s): 1305 - 1308
    12/16/2024 Authors: Dib SM; Wimalasena S; Graciaa DS; Rouphael N
  • Relative Contribution of Diagnostic Testing to the Diagnosis of Respiratory Syncytial Virus in Hospitalized Adults in the United States.
    J Infect Dis Volume: 230 Page(s): 1342 - 1351
    12/16/2024 Authors: Anderson EJ; Tippett A; Begier E; Gibson T; Ess G; Patel V; Taylor M; Reese O; Salazar L; Jadhao S
  • Association Between SARS-CoV-2 Viral Load and COVID-19 Vaccination in 4 Phase 3 Trials.
    J Infect Dis Volume: 230 Page(s): 1384 - 1389
    12/16/2024 Authors: Janes H; Fisher LH; Kee JJ; Parameswaran L; Goepfert PA; Falsey AR; Ludwig J; Magaret CA; Gilbert PB; Kublin JG
  • Safety and immunogenicity of a ChAd155-vectored rabies vaccine compared with inactivated, purified chick embryo cell rabies vaccine in healthy adults.
    Vaccine Volume: 42 Page(s): 126441
    12/02/2024 Authors: Phadke VK; Gromer DJ; Rebolledo PA; Graciaa DS; Wiley Z; Sherman AC; Scherer EM; Leary M; Girmay T; McCullough MP
  • A Phase 1, Double-Blinded, Placebo-Controlled Clinical Trial to Evaluate the Safety and Immunogenicity of HEV-239 (Hecolin) Vaccine in Healthy US Adults.
    J Infect Dis Volume: 230 Page(s): 1093 - 1101
    11/15/2024 Authors: Kao CM; Rostad CA; Nolan LE; Peters E; Kleinhenz J; Sherman JD; Tippett A; Shih JWK; Yildirim I; Agbakoba V
  • Altered Spike Immunoglobulin G Fc N-Linked Glycans Are Associated With Hyperinflammatory State in Adult Coronavirus Disease 2019 and Multisystem Inflammatory Syndrome in Children.
    Open Forum Infect Dis Volume: 11 Page(s): ofae626
    11/01/2024 Authors: Sherman JD; Karmali V; Kumar B; Simon TW; Bechnak S; Panjwani A; Ciric CR; Wang D; Huerta C; Johnson B
  • Safety and immunogenicity of a delayed booster dose of the rVSVG-ZEBOV-GP vaccine for prevention of Ebola virus disease: a multicentre, open-label, phase 2 randomised controlled trial.
    Lancet Microbe Volume: 5 Page(s): 100923
    11/01/2024 Authors: Davey RT; Collins GL; Rouphael N; Poliquin G; McConnell R; Grubbs G; Moir SL; Langley JM; Teitelbaum M; Hewlett AL
  • Prevalence, Clinical Severity, and Serotype Distribution of Pneumococcal Pneumonia Among Adults Hospitalized With Community-Acquired Pneumonia in Tennessee and Georgia, 2018-2022.
    Clin Infect Dis Volume: 79 Page(s): 838 - 847
    10/15/2024 Authors: Self WH; Johnson KD; Resser JJ; Whitney CG; Baughman A; Kio M; Grijalva CG; Traenkner J; Johnson J; Miller KF
  • Use of 3M-052-AF with Alum adjuvant in HIV trimer vaccine induces human autologous neutralizing antibodies.
    J Exp Med Volume: 221
    10/07/2024 Authors: Hahn WO; Parks KR; Shen M; Ozorowski G; Janes H; Ballweber-Fleming L; Woodward Davis AS; Duplessis C; Tomai M; Dey AK
  • Acute and persistent responses after H5N1 vaccination in humans.
    Cell Rep Volume: 43 Page(s): 114706
    09/24/2024 Authors: Apps R; Biancotto A; Candia J; Kotliarov Y; Perl S; Cheung F; Farmer R; Mul MP; Rachmaninoff N; Chen J
  • SARS-CoV-2 RNA and Nucleocapsid Antigen Are Blood Biomarkers Associated With Severe Disease Outcomes That Improve in Response to Remdesivir.
    J Infect Dis Volume: 230 Page(s): 624 - 634
    09/23/2024 Authors: Singh K; Rubenstein K; Callier V; Shaw-Saliba K; Rupert A; Dewar R; Laverdure S; Highbarger H; Lallemand P; Huang M-L
  • Human Immunodeficiency Virus Vaccine: Promise and Challenges.
    Infect Dis Clin North Am Volume: 38 Page(s): 475 - 485
    09/01/2024 Authors: Graciaa DS; Walsh SR; Rouphael N
  • COVID-19 Vaccine Efficacy in Participants With Weakened Immune Systems From 4 Randomized Controlled Trials.
    Clin Infect Dis Volume: 79 Page(s): 364 - 374
    08/16/2024 Authors: Sherman AC; Tuan J; Cantos VD; Adeyiga O; Mahoney S; Ortega-Villa AM; Tillman A; Whitaker J; Woodward Davis AS; Leav B
  • The Relationship between Immunogenicity and Reactogenicity of Seasonal Influenza Vaccine Using Different Delivery Methods.
    Vaccines (Basel) Volume: 12
    07/21/2024 Authors: Gromer DJ; Plikaytis BD; McCullough MP; Wimalasena ST; Rouphael N
  • Burden of Vaccine-Preventable Diseases in People Living with HIV.
    Vaccines (Basel) Volume: 12
    07/16/2024 Authors: Samaha H; Yigitkanli A; Naji A; Kazzi B; Tanios R; Dib SM; Ofotokun I; Rouphael N
  • Altered spike IgG Fc N-linked glycans are associated with hyperinflammatory state in adult COVID and Multisystem Inflammatory Syndrome in Children.
    medRxiv
    07/14/2024 Authors: Sherman JD; Karmali V; Kumar B; Simon TW; Bechnak S; Panjwani A; Ciric CR; Wang D; Huerta C; Johnson B
  • A Phase 2 Clinical Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of Different Prime-Boost Vaccination Schedules of 2013 and 2017 A(H7N9) Inactivated Influenza Virus Vaccines Administered With and Without AS03 Adjuvant in Healthy US Adults.
    Clin Infect Dis Volume: 78 Page(s): 1757 - 1768
    06/14/2024 Authors: Rostad CA; Atmar RL; Walter EB; Frey S; Meier JL; Sherman AC; Lai L; Tsong R; Kao CM; Raabe V
  • Phase 1 Open-Label Dose Escalation Trial for the Development of a Human Bacillus Calmette-Gurin Challenge Model for Assessment of Tuberculosis Immunity In Vivo.
    J Infect Dis Volume: 229 Page(s): 1498 - 1508
    05/15/2024 Authors: Blazevic A; Edwards RL; Xia M; Eickhoff CS; Hamzabegovic F; Meza KA; Ning H; Tennant J; Mosby KJ; Ritchie JC
  • HIV BG505 SOSIP.664 trimer with 3M-052-AF/alum induces human autologous tier-2 neutralizing antibodies.
    medRxiv
    05/09/2024 Authors: Hahn WO; Parks KR; Shen M; Ozorowski G; Janes H; Ballweber-Fleming L; Woodward Davis AS; Duplessis C; Tomai M; Dey AK
  • SARS-CoV-2 Viral Load in the Nasopharynx at Time of First Infection Among Unvaccinated Individuals: A Secondary Cross-Protocol Analysis of 4 Randomized Trials.
    JAMA Netw Open Volume: 7 Page(s): e2412835
    05/01/2024 Authors: Fisher LH; Kee JJ; Liu A; Espinosa CM; Randhawa AK; Ludwig J; Magaret CA; Robinson ST; Gilbert PB; Hyrien O
  • Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality.
    J Clin Invest Volume: 134
    05/01/2024 Authors: Gygi JP; Maguire C; Patel RK; Shinde P; Konstorum A; Shannon CP; Xu L; Hoch A; Jayavelu ND; Haddad EK
  • Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology.
    Sci Transl Med Volume: 16 Page(s): eadj5154
    04/17/2024 Authors: Phan HV; Tsitsiklis A; Maguire CP; Haddad EK; Becker PM; Kim-Schulze S; Lee B; Chen J; Hoch A; Pickering H
  • Influenza Vaccine Effectiveness Pre-pandemic Among Adults Hospitalized With Congestive Heart Failure or Chronic Obstructive Pulmonary Disease and Older Adults.
    Clin Infect Dis Volume: 78 Page(s): 1065 - 1072
    04/10/2024 Authors: Tippett A; Ess G; Hussaini L; Reese O; Salazar L; Kelly M; Taylor M; Ciric C; Keane A; Cheng A
  • AS03 adjuvant enhances the magnitude, persistence, and clonal breadth of memory B cell responses to a plant-based COVID-19 vaccine in humans.
    Sci Immunol Volume: 9 Page(s): eadi8039
    04/05/2024 Authors: Grigoryan L; Feng Y; Bellusci L; Lai L; Wali B; Ellis M; Yuan M; Arunachalam PS; Hu M; Kowli S
  • Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials.
    NPJ Vaccines Volume: 9 Page(s): 67
    03/29/2024 Authors: Happe M; Hofstetter AR; Wang J; Yamshchikov GV; Holman LA; Novik L; Strom L; Kiweewa F; Wakabi S; Millard M
  • Immunomodulators for immunocompromised patients hospitalized for COVID-19: a meta-analysis of randomized controlled trials.
    EClinicalMedicine Volume: 69 Page(s): 102472
    03/01/2024 Authors: Siempos II; Kalil AC; Belhadi D; Veiga VC; Cavalcanti AB; Branch-Elliman W; Papoutsi E; Gkirgkiris K; Xixi NA; Kotanidou A
  • Safety and Immunogenicity of a Delayed Heterologous Avian Influenza A(H7N9) Vaccine Boost Following Different Priming Regimens: A Randomized Clinical Trial.
    J Infect Dis Volume: 229 Page(s): 327 - 340
    02/14/2024 Authors: El Sahly HM; Yildirim I; Frey SE; Winokur P; Jackson LA; Bernstein DI; Creech CB; Chen WH; Rupp RE; Whitaker JA
  • Host-Microbe Multiomic Profiling Reveals Age-Dependent COVID-19 Immunopathology.
    medRxiv
    02/13/2024 Authors: Van Phan H; Tsitsiklis A; Maguire CP; Haddad EK; Becker PM; Kim-Schulze S; Lee B; Chen J; Hoch A; Pickering H
  • XBB.1.5 monovalent booster improves antibody binding and neutralization against emerging SARS-CoV-2 Omicron variants.
    bioRxiv
    02/05/2024 Authors: Jain S; Kumar S; Lai L; Linderman S; Malik AA; Ellis ML; Godbole S; Solis D; Sahoo MK; Bechnak K
  • Immunogenicity and safety of varying dosages of a fifth-wave influenza A/H7N9 inactivated vaccine given with and without AS03 adjuvant in healthy adults.
    Vaccine Volume: 42 Page(s): 295 - 309
    01/12/2024 Authors: Jackson LA; Stapleton JT; Walter EB; Chen WH; Rouphael NG; Anderson EJ; Neuzil KM; Winokur PL; Smith MJ; Schmader KE
  • IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition.
    Nat Commun Volume: 15 Page(s): 404
    01/09/2024 Authors: Haslund-Gourley BS; Woloszczuk K; Hou J; Connors J; Cusimano G; Bell M; Taramangalam B; Fourati S; Mege N; Bernui M
  • Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study.
    Nat Commun Volume: 15 Page(s): 216
    01/03/2024 Authors: Ozonoff A; Jayavelu ND; Liu S; Melamed E; Milliren CE; Qi J; Geng LN; McComsey GA; Cairns CB; Baden LR
  • SWIFT clustering analysis of intracellular cytokine staining flow cytometry data of the HVTN 105 vaccine trial reveals high frequencies of HIV-specific CD4+ T cell responses and associations with humoral responses.
    Front Immunol Volume: 15 Page(s): 1347926
    01/01/2024 Authors: Mosmann TR; Rebhahn JA; De Rosa SC; Keefer MC; McElrath MJ; Rouphael NG; Pantaleo G; Gilbert PB; Corey L; Kobie JJ
  • Qualification of a 21-valent pneumococcal urine antigen detection assay and development of clinical positivity cutoffs.
    Bioanalysis Volume: 16 Page(s): 669 - 680
    01/01/2024 Authors: Choudhury A; Zhang Y; Ma J; Li R; Chamcha R; Akgul A; Stachura N; Follmer T; Newhard W; Jackson G
  • Longitudinal fecal shedding of SARS-CoV-2, pepper mild mottle virus, and human mitochondrial DNA in COVID-19 patients.
    Front Med (Lausanne) Volume: 11 Page(s): 1417967
    01/01/2024 Authors: Liu P; Sablon O; Wang Y; Hilton SP; Khalil L; Ingersoll JM; Truell J; Edupuganti S; Alaaeddine G; Naji A
  • Immunogenicity of a 2-Dose Regimen of Moderna mRNA Beta/Omicron BA.1 Bivalent Variant Vaccine Boost in a Randomized Clinical Trial.
    J Infect Dis Volume: 228 Page(s): 1662 - 1666
    12/20/2023 Authors: Rouphael NG; Branche AR; Diemert DJ; Falsey AR; Losada C; Baden LR; Frey SE; Whitaker JA; Little SJ; Kamidani S
  • Host-Microbe Multi-omic Profiling Identifies a Unique Program of COVID-19 Inflammatory Dysregulation in Solid Organ Transplant Recipients.
    Res Sq
    12/20/2023 Authors: Langelier C; Pickering H; Schaenman J; Phan H; Maguire C; Tsitsiklis A; Rouphael N; Higuita N; Atkinson M; Breckenridge S
  • Natural infection by Zika virus but not DNA vaccination consistently elicits antibodies that compete with two potently neutralising monoclonal antibodies targeting distinct epitopes.
    EBioMedicine Volume: 98 Page(s): 104875
    12/01/2023 Authors: Smith TC; Espinoza DO; Zhu Y; Cardona-Ospina JA; Bowman NM; Becker-Dreps S; Rouphael N; Rodriguez-Morales AJ; Bucardo F; Edupuganti S
  • Corrigendum to "Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: results from the IMPACC study" [eBioMedicine 83 (2022) 104208].
    EBioMedicine Volume: 98 Page(s): 104860
    12/01/2023 Authors: Ozonoff A; Schaenman J; Jayavelu ND; Milliren CE; Calfee CS; Cairns CB; Kraft M; Baden LR; Shaw AC; Krammer F
  • Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants.
    bioRxiv
    11/06/2023 Authors: Gygi JP; Maguire C; Patel RK; Shinde P; Konstorum A; Shannon CP; Xu L; Hoch A; Jayavelu ND; Network I
  • Efficacy of a bivalent (D614+B.1.351) SARS-CoV-2 recombinant protein vaccine with AS03 adjuvant in adults: a phase 3, parallel, randomised, modified double-blind, placebo-controlled trial.
    Lancet Respir Med Volume: 11 Page(s): 975 - 990
    11/01/2023 Authors: Dayan GH; Rouphael N; Walsh SR; Chen A; Grunenberg N; Allen M; Antony J; Asante KP; Bhate AS; Beresnev T
  • Joint statement in support of hepatitis C human challenge studies.
    Lancet Gastroenterol Hepatol Volume: 8 Page(s): 967 - 969
    11/01/2023 Authors: Alter HJ; Barnes E; Biondi MJ; Cox AL; Eberts JD; Feld JJ; Liang TJ; Morrison J; Rice CM; Shoukry NH
  • Daily fosfomycin versus levofloxacin for complicated urinary tract infections.
    mBio Volume: 14 Page(s): e0167723
    10/31/2023 Authors: Rouphael N; Winokur P; Keefer MC; Traenkner J; Drobeniuc A; Doi Y; Munsiff S; Fowler VG; Evans S; Oler RE
  • Priorities and Progress in Gram-negative Bacterial Infection Research by the Antibacterial Resistance Leadership Group.
    Clin Infect Dis Volume: 77 Page(s): S305 - S313
    10/16/2023 Authors: Satlin MJ; van Duin D; Tamma PD; Lodise TP; Van Tyne D; Rodvold KA; Rouphael N; Evans SR; Fowler VG; Hamasaki T
  • The Future Ain't What It Used to BeOut With the OldIn With the Better: Antibacterial Resistance Leadership Group Innovations.
    Clin Infect Dis Volume: 77 Page(s): S321 - S330
    10/16/2023 Authors: Evans SR; Patel R; Hamasaki T; Howard-Anderson J; Kinamon T; King HA; Collyar D; Cross HR; Chambers HF; Fowler VG
  • Relationship of Heterologous Virus Responses and Outcomes in Hospitalized COVID-19 Patients.
    J Immunol Volume: 211 Page(s): 1224 - 1231
    10/15/2023 Authors: Rosenberg-Hasson Y; Holmes TH; Diray-Arce J; Chen J; Kellogg R; Snyder M; Becker PM; Ozonoff A; Rouphael N; Reed EF
  • Risk of COVID-19 after natural infection or vaccination.
    EBioMedicine Volume: 96 Page(s): 104799
    10/01/2023 Authors: Rick A-M; Laurens MB; Huang Y; Yu C; Martin TCS; Rodriguez CA; Rostad CA; Maboa RM; Baden LR; El Sahly HM
  • Efficacy of a monovalent (D614) SARS-CoV-2 recombinant protein vaccine with AS03 adjuvant in adults: a phase 3, multi-country study.
    EClinicalMedicine Volume: 64 Page(s): 102168
    10/01/2023 Authors: Dayan GH; Rouphael N; Walsh SR; Chen A; Grunenberg N; Allen M; Antony J; Bhate AS; Beresnev T; Bonaparte MI
  • Blockade Antibody Responses in Human Subjects Challenged with a New Snow Mountain Virus Inoculum.
    Res Sq
    09/11/2023 Authors: Ibaraki M; Lai L; Huerta C; Natrajan MS; Collins MH; Anderson EJ; Mulligan MJ; Rouphael N; Moe CL; Liu P
  • Comparison of bivalent and monovalent SARS-CoV-2 variant vaccines: the phase 2 randomized open-label COVAIL trial.
    Nat Med Volume: 29 Page(s): 2334 - 2346
    09/01/2023 Authors: Branche AR; Rouphael NG; Diemert DJ; Falsey AR; Losada C; Baden LR; Frey SE; Whitaker JA; Little SJ; Anderson EJ
  • Immunogenicity of the BA.1 and BA.4/BA.5 Severe Acute Respiratory Syndrome Coronavirus 2 Bivalent Boosts: Preliminary Results From the COVAIL Randomized Clinical Trial.
    Clin Infect Dis Volume: 77 Page(s): 560 - 564
    08/22/2023 Authors: Branche AR; Rouphael NG; Losada C; Baden LR; Anderson EJ; Luetkemeyer AF; Diemert DJ; Winokur PL; Presti RM; Kottkamp AC
  • A Multicenter, Controlled Human Infection Study of Influenza A(H1N1)pdm09 in Healthy Adults.
    J Infect Dis Volume: 228 Page(s): 287 - 298
    08/11/2023 Authors: Ortiz JR; Bernstein DI; Hoft DF; Woods CW; McClain MT; Frey SE; Brady RC; Bryant C; Wegel A; Frenck RW
  • COVID-19 Vaccination Among Patients Receiving Maintenance Renal Replacement Therapy: Immune Response, Real-World Effectiveness, and Implications for the Future.
    J Infect Dis Volume: 228 Page(s): S46 - S54
    08/04/2023 Authors: Rouphael N; Bausch-Jurken M
  • Modifiers of COVID-19 vaccine efficacy: Results from four COVID-19 prevention network efficacy trials.
    Vaccine Volume: 41 Page(s): 4899 - 4906
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    01/27/2021 Authors: Shen H; Forgacs D; Chapla D; Moremen KW; Wells L; Hamer SA; Tompkins SM; Ross TM; Rouphael N; Edupuganti S
  • Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination.
    N Engl J Med Volume: 384 Page(s): 80 - 82
    01/07/2021 Authors: Widge AT; Rouphael NG; Jackson LA; Anderson EJ; Roberts PC; Makhene M; Chappell JD; Denison MR; Stevens LJ; Pruijssers AJ
  • Staphylococcus simulans: A rare uropathogen.
    IDCases Volume: 25 Page(s): e01202
    01/01/2021 Authors: Drobeniuc A; Traenkner J; Rebolledo PA; Ghazaryan V; Rouphael N
  • Immune Responses to SARS-CoV-2 in Solid Organ Transplant Recipients.
    Curr Transplant Rep Volume: 8 Page(s): 127 - 139
    01/01/2021 Authors: Phadke VK; Scanlon N; Jordan SC; Rouphael NG
  • Application of SARS-CoV-2 Serology to Address Public Health Priorities.
    Front Public Health Volume: 9 Page(s): 744535
    01/01/2021 Authors: Sherman AC; Smith T; Zhu Y; Taibl K; Howard-Anderson J; Landay T; Pisanic N; Kleinhenz J; Simon TW; Espinoza D
  • Mycobacterium mucogenicum bacteremia in an immunocompetent host: A case report and concise review.
    IDCases Volume: 23 Page(s): e01032
    01/01/2021 Authors: Beydoun N; Wiley Z; Rouphael N
  • Development and optimization of a Zika virus antibody-dependent cell-mediated cytotoxicity (ADCC) assay.
    J Immunol Methods Volume: 488 Page(s): 112900
    01/01/2021 Authors: Chen X; Anderson LJ; Rostad CA; Ding L; Lai L; Mulligan M; Rouphael N; Natrajan MS; McCracken C; Anderson EJ
  • Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults.
    N Engl J Med Volume: 383 Page(s): 2427 - 2438
    12/17/2020 Authors: Anderson EJ; Rouphael NG; Widge AT; Jackson LA; Roberts PC; Makhene M; Chappell JD; Denison MR; Stevens LJ; Pruijssers AJ
  • COVID-19 Serology at Population Scale: SARS-CoV-2-Specific Antibody Responses in Saliva.
    J Clin Microbiol Volume: 59
    12/17/2020 Authors: Pisanic N; Randad PR; Kruczynski K; Manabe YC; Thomas DL; Pekosz A; Klein SL; Betenbaugh MJ; Clarke WA; Laeyendecker O
  • Development of a Rapid Focus Reduction Neutralization Test Assay for Measuring SARS-CoV-2 Neutralizing Antibodies.
    Curr Protoc Immunol Volume: 131 Page(s): e116
    12/01/2020 Authors: Vanderheiden A; Edara VV; Floyd K; Kauffman RC; Mantus G; Anderson E; Rouphael N; Edupuganti S; Shi P-Y; Menachery VD
  • Immunomodulatory Low-Dose Whole-Lung Radiation for Patients with COVID-19-Related Pneumonia.
    Int J Radiat Oncol Biol Phys Volume: 108 Page(s): 1401
    12/01/2020 Authors: Hess CB; Buchwald ZS; Stokes WA; Nasti T; Switchenko J; Weinberg BD; Rouphael N; Steinberg JP; Godette KD; Murphy DJ
  • An mRNA Vaccine against SARS-CoV-2 - Preliminary Report.
    N Engl J Med Volume: 383 Page(s): 1920 - 1931
    11/12/2020 Authors: Jackson LA; Anderson EJ; Rouphael NG; Roberts PC; Makhene M; Coler RN; McCullough MP; Chappell JD; Denison MR; Stevens LJ
  • The Effects of Imprinting and Repeated Seasonal Influenza Vaccination on Adaptive Immunity after Influenza Vaccination.
    Vaccines (Basel) Volume: 8
    11/07/2020 Authors: Sherman AC; Lai L; Bower M; Natrajan MS; Huerta C; Karmali V; Kleinhenz J; Xu Y; Rouphael N; Mulligan MJ
  • Remdesivir for the Treatment of Covid-19 - Final Report.
    N Engl J Med Volume: 383 Page(s): 1813 - 1826
    11/05/2020 Authors: Beigel JH; Tomashek KM; Dodd LE; Mehta AK; Zingman BS; Kalil AC; Hohmann E; Chu HY; Luetkemeyer A; Kline S
  • Acceptability of an inactivated influenza vaccine delivered by microneedle patch: Results from a phase I clinical trial of safety, reactogenicity, and immunogenicity.
    Vaccine Volume: 38 Page(s): 7175 - 7181
    10/21/2020 Authors: Frew PM; Paine MB; Rouphael N; Schamel J; Chung Y; Mulligan MJ; Prausnitz MR
  • Safety and immunogenicity of two heterologous HIV vaccine regimens in healthy, HIV-uninfected adults (TRAVERSE): a randomised, parallel-group, placebo-controlled, double-blind, phase 1/2a study.
    Lancet HIV Volume: 7 Page(s): e688 - e698
    10/01/2020 Authors: Baden LR; Stieh DJ; Sarnecki M; Walsh SR; Tomaras GD; Kublin JG; McElrath MJ; Alter G; Ferrari G; Montefiori D
  • Effect of Concomitant Antibiotic and Vaccine Administration on Serologic Responses to Rotavirus Vaccine.
    J Pediatric Infect Dis Soc Volume: 9 Page(s): 479 - 482
    09/17/2020 Authors: Anderson EJ; Lopman B; Yi J; Libster R; Creech CB; El-Khorazaty J; Baqar S; Yildirim I; Kao C; Rouphael N
  • Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans.
    Science Volume: 369 Page(s): 1210 - 1220
    09/04/2020 Authors: Arunachalam PS; Wimmers F; Mok CKP; Perera RAPM; Scott M; Hagan T; Sigal N; Feng Y; Bristow L; Tak-Yin Tsang O
  • Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans.
    Proc Natl Acad Sci U S A Volume: 117 Page(s): 17957 - 17964
    07/28/2020 Authors: Ellebedy AH; Nachbagauer R; Jackson KJL; Dai Y-N; Han J; Alsoussi WB; Davis CW; Stadlbauer D; Rouphael N; Chromikova V
  • Alterations in the Human Plasma Lipidome in Response to Tularemia Vaccination.
    Vaccines (Basel) Volume: 8
    07/24/2020 Authors: Maner-Smith KM; Goll JB; Khadka M; Jensen TL; Colucci JK; Gelber CE; Albert CJ; Bosinger SE; Franke JD; Natrajan M
  • Proteomic Analysis of Human Immune Responses to Live-Attenuated Tularemia Vaccine.
    Vaccines (Basel) Volume: 8
    07/24/2020 Authors: Chang Y-H; Duong DM; Goll JB; Wood DC; Jensen TL; Yin L; Gelber CE; Seyfried NT; Anderson E; Natrajan MS
  • Transcriptomic and Metabolic Responses to a Live-Attenuated Francisella tularensis Vaccine.
    Vaccines (Basel) Volume: 8
    07/24/2020 Authors: Goll JB; Li S; Edwards JL; Bosinger SE; Jensen TL; Wang Y; Hooper WF; Gelber CE; Sanders KL; Anderson EJ
  • A Retrospective Chart Review on the Role of Suppressive Therapy in the Management of Spinal Infections Involving Hardware.
    Open Forum Infect Dis Volume: 7 Page(s): ofaa253
    07/01/2020 Authors: Beydoun N; Tandon S; Krengel S; Johnson E; Palacio Bedoya F; Moore M; Refai D; Rouphael N
  • Triplex Real-Time RT-PCR for Severe Acute Respiratory Syndrome Coronavirus 2.
    Emerg Infect Dis Volume: 26 Page(s): 1633 - 1635
    07/01/2020 Authors: Waggoner JJ; Stittleburg V; Pond R; Saklawi Y; Sahoo MK; Babiker A; Hussaini L; Kraft CS; Pinsky BA; Anderson EJ
  • Duration of Cellular and Humoral Responses after Quadrivalent Human Papillomavirus Vaccination in Healthy Female Adults with or without Prior Type 16 and/or 18 Exposure.
    Vaccines (Basel) Volume: 8
    06/30/2020 Authors: Lai L; Ault K; Rouphael N; Beck A; Domjahn B; Xu Y; Anderson EJ; Cheng A; Nakamura A; Hoagland RJ
  • Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients.
    Cell Rep Med Volume: 1 Page(s): 100040
    06/23/2020 Authors: Suthar MS; Zimmerman MG; Kauffman RC; Mantus G; Linderman SL; Hudson WH; Vanderheiden A; Nyhoff L; Davis CW; Adekunle O
  • Persistence of Varicella-Zoster Virus-Specific Plasma Cells in Adult Human Bone Marrow following Childhood Vaccination.
    J Virol Volume: 94
    06/16/2020 Authors: Eberhardt CS; Wieland A; Nasti TH; Grifoni A; Wilson E; Schmid DS; Pulendran B; Sette A; Waller EK; Rouphael N
  • The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients.
    Sci Immunol Volume: 5
    06/11/2020 Authors: Premkumar L; Segovia-Chumbez B; Jadi R; Martinez DR; Raut R; Markmann A; Cornaby C; Bartelt L; Weiss S; Park Y
  • COVID-19 serology at population scale: SARS-CoV-2-specific antibody responses in saliva.
    medRxiv
    05/26/2020 Authors: Randad PR; Pisanic N; Kruczynski K; Manabe YC; Thomas D; Pekosz A; Klein SL; Betenbaugh MJ; Clarke WA; Laeyendecker O
  • Rapid generation of neutralizing antibody responses in COVID-19 patients.
    medRxiv
    05/08/2020 Authors: Suthar MS; Zimmerman M; Kauffman R; Mantus G; Linderman S; Vanderheiden A; Nyhoff L; Davis C; Adekunle S; Affer M
  • Anti-Vibrio cholerae responses in the human periphery and intestine following a live-attenuated vaccine
    Volume: 204
    05/01/2020 Authors: Nyhoff LE; Adekunle O; Kauffman RC; Keilin S; Rouphael N; Wrammert J
  • Human B cell responses to a live attenuated cholera vaccine
    Volume: 204
    05/01/2020 Authors: Adekunle O; Kauffman R; Cho A; Nyhoff L; Rouphael N; Wrammert J
  • Baseline Levels of Influenza-Specific B Cells and T Cell Responses Modulate Human Immune Responses to Swine Variant Influenza A/H3N2 Vaccine.
    Vaccines (Basel) Volume: 8
    03/13/2020 Authors: Lai L; Rouphael N; Xu Y; Sherman AC; Edupuganti S; Anderson EJ; Lankford-Turner P; Wang D; Keitel W; McNeal MM
  • Plasmablast, Memory B Cell, CD4+ T Cell, and Circulating Follicular Helper T Cell Responses to a Non-Replicating Modified Vaccinia Ankara Vaccine.
    Vaccines (Basel) Volume: 8
    02/06/2020 Authors: Anderson EJ; Lai L; Wrammert J; Kabbani S; Xu Y; Priyamvada L; Hill H; Goll JB; Jensen TL; Kao C
  • INFLUENZA VACCINE EFFECTIVENESS AMONG HOSPITALIZED ADULTS AGE >= 50 WITH ACUTE RESPIRATORY TRACT INFECTIONS OR WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE OR CONGESTIVE HEART FAILURE EXACERBATIONS OF ANY AGE >= 18 YEARS
    Volume: 68 Page(s): 693 - 693
    02/01/2020 Authors: Kelly M; Yildirim I; Tippett A; Hussaini L; Bristow L; Gibson T; Hart MB; Deovic R; Stephens K; Swerdlow DL
  • Landscapes of binding antibody and T-cell responses to pox-protein HIV vaccines in Thais and South Africans.
    PLoS One Volume: 15 Page(s): e0226803
    01/01/2020 Authors: Zhao LP; Fiore-Gartland A; Carpp LN; Cohen KW; Rouphael N; Fleurs L; Dintwe O; Zhao M; Moodie Z; Fong Y
  • The Role of Systems Vaccinology in Understanding the Immune Defects to Vaccination in Solid Organ Transplant Recipients.
    Front Immunol Volume: 11 Page(s): 582201
    01/01/2020 Authors: Scanlon N; Saklawi Y; Rouphael N
  • Systems Vaccinology for a Live Attenuated Tularemia Vaccine Reveals Unique Transcriptional Signatures That Predict Humoral and Cellular Immune Responses.
    Vaccines (Basel) Volume: 8
    12/24/2019 Authors: Natrajan MS; Rouphael N; Lai L; Kazmin D; Jensen TL; Weiss DS; Ibegbu C; Sztein MB; Hooper WF; Hill H
  • DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial.
    J Clin Invest Volume: 129 Page(s): 4769 - 4785
    11/01/2019 Authors: Rouphael NG; Morgan C; Li SS; Jensen R; Sanchez B; Karuna S; Swann E; Sobieszczyk ME; Frank I; Wilson GJ
  • Occupational Exposure to the Ugandan Research Strain (MR766) of Zika Virus.
    Open Forum Infect Dis Volume: 6 Page(s): ofz420
    10/01/2019 Authors: Lichtenberger PN; Ricciardi MJ; Solorzano D; Raccamarich P; Leda A; Sharkey M; Watkins DI; El Sahly H; Rouphael N; Mulligan MJ
  • Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans.
    Cell Volume: 178 Page(s): 1313 - 1328.e13
    09/05/2019 Authors: Hagan T; Cortese M; Rouphael N; Boudreau C; Linde C; Maddur MS; Das J; Wang H; Guthmiller J; Zheng N-Y
  • Phase Ib Trial To Evaluate the Safety and Pharmacokinetics of Multiple Ascending Doses of Filociclovir (MBX-400, Cyclopropavir) in Healthy Volunteers.
    Antimicrob Agents Chemother Volume: 63
    09/01/2019 Authors: Rouphael NG; Hurwitz SJ; Hart M; Beck A; Anderson EJ; Deye G; Osborn B; Cai SY; Focht C; Amegashie C
  • The Effect of Anticoagulants, Temperature, and Time on the Human Plasma Metabolome and Lipidome from Healthy Donors as Determined by Liquid Chromatography-Mass Spectrometry.
    Biomolecules Volume: 9
    05/23/2019 Authors: Khadka M; Todor A; Maner-Smith KM; Colucci JK; Tran V; Gaul DA; Anderson EJ; Natrajan MS; Rouphael N; Mulligan MJ
  • Sequential, Multiple-Assignment, Randomized Trials for COMparing Personalized Antibiotic StrategieS (SMART-COMPASS).
    Clin Infect Dis Volume: 68 Page(s): 1961 - 1967
    05/17/2019 Authors: Evans SR; Follmann D; Liu Y; Holland T; Doernberg SB; Rouphael N; Hamasaki T; Jiang Y; Lok JJ; Tran TTT
  • Streptococcus pneumoniae colonization after introduction of 13-valent pneumococcal conjugate vaccine for US adults 65 years of age and older, 2015-2016.
    Vaccine Volume: 37 Page(s): 1094 - 1100
    02/14/2019 Authors: Milucky J; Carvalho MDG; Rouphael N; Bennett NM; Talbot HK; Harrison LH; Farley MM; Walston J; Pimenta F; Lessa FC
  • The Future of Flu: A Review of the Human Challenge Model and Systems Biology for Advancement of Influenza Vaccinology.
    Front Cell Infect Microbiol Volume: 9 Page(s): 107
    01/01/2019 Authors: Sherman AC; Mehta A; Dickert NW; Anderson EJ; Rouphael N
  • Clinical, Virologic, and Immunologic Characteristics of Zika Virus Infection in a Cohort of US Patients: Prolonged RNA Detection in Whole Blood.
    Open Forum Infect Dis Volume: 6 Page(s): ofy352
    01/01/2019 Authors: El Sahly HM; Gorchakov R; Lai L; Natrajan MS; Patel SM; Atmar RL; Keitel WA; Hoft DF; Barrett J; Bailey J
  • Pre-Existing Dengue Immunity Drives a DENV-Biased Plasmablast Response in ZIKV-Infected Patient.
    Viruses Volume: 11
    12/29/2018 Authors: Bhaumik SK; Priyamvada L; Kauffman RC; Lai L; Natrajan MS; Cho A; Rouphael N; Suthar MS; Mulligan MJ; Wrammert J
  • Streptococcus mitis Expressing Pneumococcal Serotype 1 Capsule.
    Sci Rep Volume: 8 Page(s): 17959
    12/19/2018 Authors: Lessa FC; Milucky J; Rouphael NG; Bennett NM; Talbot HK; Harrison LH; Farley MM; Walston J; Pimenta F; Gertz RE
  • Willingness to Participate in Vaccine-Related Clinical Trials among Older Adults.
    Int J Environ Res Public Health Volume: 15
    08/14/2018 Authors: Raheja D; Davila EP; Johnson ET; Deovi R; Paine M; Rouphael N
  • Breadth and Functionality of Varicella-Zoster Virus Glycoprotein-Specific Antibodies Identified after Zostavax Vaccination in Humans.
    J Virol Volume: 92
    07/15/2018 Authors: Sullivan NL; Reuter-Monslow MA; Sei J; Durr E; Davis CW; Chang C; McCausland M; Wieland A; Krah D; Rouphael N
  • Progress toward the global control of Neisseria meningitidis: 21st century vaccines, current guidelines, and challenges for future vaccine development.
    Hum Vaccin Immunother Volume: 14 Page(s): 1146 - 1160
    05/04/2018 Authors: Dretler AW; Rouphael NG; Stephens DS
  • Varicella-Zoster Virus DNA in Blood After Administration of Herpes Zoster Vaccine.
    J Infect Dis Volume: 217 Page(s): 1055 - 1059
    03/13/2018 Authors: Levin MJ; Cai G-Y; Lee KS; Rouphael NG; Mehta AK; Canniff J; Mulligan MJ; Weinberg A
  • Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials.
    Lancet Volume: 391 Page(s): 552 - 562
    02/10/2018 Authors: Gaudinski MR; Houser KV; Morabito KM; Hu Z; Yamshchikov G; Rothwell RS; Berkowitz N; Mendoza F; Saunders JG; Novik L
  • A RETROSPECTIVE CHART REVIEW ON MANAGEMENT OF SPINAL INFECTIONS INVOLVING HARDWARE
    Volume: 66 Page(s): 578 - 579
    02/01/2018 Authors: Beydoun N; Krengel S; Tandon S; Johnson E; Dretler A; Moore M; Refai D; Rouphael N
  • Randomized clinical trial of a single versus a double dose of 13-valent pneumococcal conjugate vaccine in adults 55 through 74years of age previously vaccinated with 23-valent pneumococcal polysaccharide vaccine.
    Vaccine Volume: 36 Page(s): 606 - 614
    01/29/2018 Authors: Jackson LA; El Sahly HM; George S; Winokur P; Edwards K; Brady RC; Rouphael N; Keitel WA; Mulligan MJ; Burton RL
  • Innate, T-, and B-Cell Responses in Acute Human Zika Patients.
    Clin Infect Dis Volume: 66 Page(s): 1 - 10
    01/06/2018 Authors: Lai L; Rouphael N; Xu Y; Natrajan MS; Beck A; Hart M; Feldhammer M; Feldpausch A; Hill C; Wu H
  • Swimming with the Pigs: A Case of Severe Soft Tissue Infection during a Caribbean Vacation.
    Case Rep Infect Dis Volume: 2018 Page(s): 4092609
    01/01/2018 Authors: Dretler AW; Jacob JT; Rouphael NG
  • Streptococcus infantis, Streptococcus mitis, and Streptococcus oralis Strains With Highly Similar cps5 Loci and Antigenic Relatedness to Serotype 5 Pneumococci.
    Front Microbiol Volume: 9 Page(s): 3199
    01/01/2018 Authors: Pimenta F; Gertz RE; Park SH; Kim E; Moura I; Milucky J; Rouphael N; Farley MM; Harrison LH; Bennett NM
  • Reply letter to "Fatal meningococcemia due to Neisseria meningitidis serogroup Y in a vaccinated child receiving eculizumab".
    Hum Vaccin Immunother Volume: 14 Page(s): 2803 - 2804
    01/01/2018 Authors: Dretler AW; Rouphael NG; Stephens DS
  • Reply to "A refugee patient with meningococcal meningitis type B.".
    Hum Vaccin Immunother Volume: 14 Page(s): 2543
    01/01/2018 Authors: Dretler A; Rouphael N; Stephens D
  • Microneedle patch for immunization of immunocompromised hosts.
    Oncotarget Volume: 8 Page(s): 93311 - 93312
    11/07/2017 Authors: Rouphael NG; Mulligan MJ
  • Tularemia vaccine: Safety, reactogenicity, "Take" skin reactions, and antibody responses following vaccination with a new lot of the Francisella tularensis live vaccine strain - A phase 2 randomized clinical Trial.
    Vaccine Volume: 35 Page(s): 4730 - 4737
    08/24/2017 Authors: Mulligan MJ; Stapleton JT; Keitel WA; Frey SE; Chen WH; Rouphael N; Edupuganti S; Beck A; Winokur PL; El Sahly HM
  • The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial.
    Lancet Volume: 390 Page(s): 649 - 658
    08/12/2017 Authors: Rouphael NG; Paine M; Mosley R; Henry S; McAllister DV; Kalluri H; Pewin W; Frew PM; Yu T; Thornburg NJ
  • Varicella-Zoster Virus-Specific Cellular Immune Responses to the Live Attenuated Zoster Vaccine in Young and Older Adults.
    J Immunol Volume: 199 Page(s): 604 - 612
    07/15/2017 Authors: Weinberg A; Canniff J; Rouphael N; Mehta A; Mulligan M; Whitaker JA; Levin MJ
  • Metabolic Phenotypes of Response to Vaccination in Humans.
    Cell Volume: 169 Page(s): 862 - 877.e17
    05/18/2017 Authors: Li S; Sullivan NL; Rouphael N; Yu T; Banton S; Maddur MS; McCausland M; Chiu C; Canniff J; Dubey S
  • Characterization of varicella zoster virus-specific monoclonal antibodies
    Volume: 198
    05/01/2017 Authors: Sullivan NL; Monslow M; Sei J; Durr E; Chang C; Mccausland M; Rouphael N; Pulendran B; Ahmed R; Vora KA
  • Safety and immunogenicity of a modified vaccinia Ankara vaccine using three immunization schedules and two modes of delivery: A randomized clinical non-inferiority trial.
    Vaccine Volume: 35 Page(s): 1675 - 1682
    03/23/2017 Authors: Jackson LA; Frey SE; El Sahly HM; Mulligan MJ; Winokur PL; Kotloff KL; Campbell JD; Atmar RL; Graham I; Anderson EJ
  • Diagnostic Importance of Hyphae on Heart Valve Tissue in Histoplasma Endocarditis and Treatment With Isavuconazole.
    Open Forum Infect Dis Volume: 4 Page(s): ofx241
    01/01/2017 Authors: Wiley Z; Woodworth MH; Jacob JT; Lockhart SR; Rouphael NG; Gullett JC; Guarner J; Workowski K
  • Biphasic Zika Illness With Rash and Joint Pain.
    Open Forum Infect Dis Volume: 4 Page(s): ofx133
    01/01/2017 Authors: Edupuganti S; Natrajan MS; Rouphael N; Lai L; Xu Y; Feldhammer M; Hill C; Patel SM; Johnson SJ; Bower M
  • Pericarditis Associated With Acute Zika Virus Infection in a Returning Traveler.
    Open Forum Infect Dis Volume: 4 Page(s): ofx103
    01/01/2017 Authors: Waggoner JJ; Rouphael N; Xu Y; Natrajan M; Lai L; Patel SM; Levit RD; Edupuganti S; Mulligan MJ
  • DNA and Protein Co-administration Elicits Higher HIV-specific nAb and Comparable CD4+T-cell Responses as Traditional Prime/Boost Regimens (HVTN 105)
    Volume: 32 Page(s): 67 - 67
    10/01/2016 Authors: Rouphael N; Morgan C; Li S; Jensen R; Sanchez B; Swann E; Sobieszczyk M; Frank I; Wilson G; Tieu H
  • Retrospective Study of Cryptococcal Meningitis With Elevated Minimum Inhibitory Concentration to Fluconazole in Immunocompromised Patients.
    Open Forum Infect Dis Volume: 3 Page(s): ofw076
    04/01/2016 Authors: Nasri H; Kabbani S; Bou Alwan M; Wang YF; Rebolledo PA; Kraft CS; Nguyen ML; Anderson AM; Rouphael N
  • Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures.
    Immunity Volume: 43 Page(s): 1186 - 1198
    12/15/2015 Authors: Nakaya HI; Hagan T; Duraisingham SS; Lee EK; Kwissa M; Rouphael N; Frasca D; Gersten M; Mehta AK; Gaujoux R
  • Comparison of lyophilized versus liquid modified vaccinia Ankara (MVA) formulations and subcutaneous versus intradermal routes of administration in healthy vaccinia-nave subjects.
    Vaccine Volume: 33 Page(s): 5225 - 5234
    09/22/2015 Authors: Frey SE; Wald A; Edupuganti S; Jackson LA; Stapleton JT; El Sahly H; El-Kamary SS; Edwards K; Keyserling H; Winokur P
  • First-in-Human Evaluation of the Safety and Immunogenicity of a Recombinant Vesicular Stomatitis Virus Human Immunodeficiency Virus-1 gag Vaccine (HVTN 090).
    Open Forum Infect Dis Volume: 2 Page(s): ofv082
    09/01/2015 Authors: Fuchs JD; Frank I; Elizaga ML; Allen M; Frahm N; Kochar N; Li S; Edupuganti S; Kalams SA; Tomaras GD
  • Safety and Immunogenicity of a Subvirion Monovalent Unadjuvanted Inactivated Influenza A(H3N2) Variant Vaccine in Healthy Persons 18 Years Old.
    J Infect Dis Volume: 212 Page(s): 552 - 561
    08/15/2015 Authors: Keitel WA; Jackson LA; Edupuganti S; Winokur PL; Mulligan MJ; Thornburg NJ; Patel SM; Rouphael NG; Lai L; Bangaru S
  • Safety and Immunogenicity of a Recombinant Adenovirus Serotype 35-Vectored HIV-1 Vaccine in Adenovirus Serotype 5 Seronegative and Seropositive Individuals.
    J AIDS Clin Res Volume: 6
    05/01/2015 Authors: Fuchs JD; Bart P-A; Frahm N; Morgan C; Gilbert PB; Kochar N; DeRosa SC; Tomaras GD; Wagner TM; Baden LR
  • RETROSPECTIVE REVIEW OF RESISTANT CRYPTOCOCCAL MENINGITIS IN IMMUNOCOMPROMISED HOSTS
    Volume: 30 Page(s): S247 - S247
    04/01/2015 Authors: Nasri H; Kabbani S; Alwan MB; Anderson A; Rouphael N
  • DNA priming for seasonal influenza vaccine: a phase 1b double-blind randomized clinical trial.
    PLoS One Volume: 10 Page(s): e0125914
    01/01/2015 Authors: Ledgerwood JE; Bellamy AR; Belshe R; Bernstein DI; Edupuganti S; Patel SM; Renehan P; Zajdowicz T; Schwartz R; Koup R
  • Phase II trial in adults of concurrent or sequential 2009 pandemic H1N1 and 2009-2010 seasonal trivalent influenza vaccinations.
    Vaccine Volume: 33 Page(s): 163 - 173
    01/01/2015 Authors: Frey SE; Bernstein DI; Brady RC; Keitel WA; El Sahly H; Rouphael NG; Mulligan MJ; Atmar RL; Edupuganti S; Patel SM
  • Point-of-Use Mixing of Influenza H5N1 Vaccine and MF59 Adjuvant for Pandemic Vaccination Preparedness: Antibody Responses and Safety. A Phase 1 Clinical Trial.
    Open Forum Infect Dis Volume: 1 Page(s): ofu102
    12/01/2014 Authors: Mulligan MJ; Bernstein DI; Frey S; Winokur P; Rouphael N; Dickey M; Edupuganti S; Spearman P; Anderson E; Graham I
  • Immunogenicity and safety of four different dosing regimens of anthrax vaccine adsorbed for post-exposure prophylaxis for anthrax in adults.
    Vaccine Volume: 32 Page(s): 6284 - 6293
    10/29/2014 Authors: Bernstein DI; Jackson L; Patel SM; El Sahly HM; Spearman P; Rouphael N; Rudge TL; Hill H; Goll JB
  • Impact of body mass index on immunogenicity of pandemic H1N1 vaccine in children and adults.
    J Infect Dis Volume: 210 Page(s): 1270 - 1274
    10/15/2014 Authors: Callahan ST; Wolff M; Hill HR; Edwards KM; NIAID Vaccine and Treatment Evaluation Unit (VTEU) Pandemic H1N1 Vaccine Study Group
  • Immunogenicity of avian influenza A/Anhui/01/2005(H5N1) vaccine with MF59 adjuvant: a randomized clinical trial.
    JAMA Volume: 312 Page(s): 1420 - 1428
    10/08/2014 Authors: Belshe RB; Frey SE; Graham IL; Anderson EL; Jackson LA; Spearman P; Edupuganti S; Mulligan MJ; Rouphael N; Winokur P
  • Serological responses to an avian influenza A/H7N9 vaccine mixed at the point-of-use with MF59 adjuvant: a randomized clinical trial.
    JAMA Volume: 312 Page(s): 1409 - 1419
    10/08/2014 Authors: Mulligan MJ; Bernstein DI; Winokur P; Rupp R; Anderson E; Rouphael N; Dickey M; Stapleton JT; Edupuganti S; Spearman P
  • Specificity and 6-month durability of immune responses induced by DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles.
    J Infect Dis Volume: 210 Page(s): 99 - 110
    07/01/2014 Authors: Goepfert PA; Elizaga ML; Seaton K; Tomaras GD; Montefiori DC; Sato A; Hural J; DeRosa SC; Kalams SA; McElrath MJ
  • Broadly reactive human CD8 T cells that recognize an epitope conserved between VZV, HSV and EBV.
    PLoS Pathog Volume: 10 Page(s): e1004008
    03/01/2014 Authors: Chiu C; McCausland M; Sidney J; Duh F-M; Rouphael N; Mehta A; Mulligan M; Carrington M; Wieland A; Sullivan NL
  • Molecular signatures of antibody responses derived from a systems biology study of five human vaccines.
    Nat Immunol Volume: 15 Page(s): 195 - 204
    02/01/2014 Authors: Li S; Rouphael N; Duraisingham S; Romero-Steiner S; Presnell S; Davis C; Schmidt DS; Johnson SE; Milton A; Rajam G
  • Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine.
    N Engl J Med Volume: 369 Page(s): 2083 - 2092
    11/28/2013 Authors: Hammer SM; Sobieszczyk ME; Janes H; Karuna ST; Mulligan MJ; Grove D; Koblin BA; Buchbinder SP; Keefer MC; Tomaras GD
  • Antigen-specific T cell and B cell responses to the herpes zoster vaccine Zostavax (R) in the young and elderly
    Volume: 190
    05/01/2013 Authors: Sullivan N; McCausland M; Chiu C; Sidney J; Rouphael N; Mehta A; Mulligan M; Peters B; Sette A; Pulendran B
  • Systems biology of vaccination in the elderly.
    Curr Top Microbiol Immunol Volume: 363 Page(s): 117 - 142
    01/01/2013 Authors: Duraisingham SS; Rouphael N; Cavanagh MM; Nakaya HI; Goronzy JJ; Pulendran B
  • Strategies to increase responsiveness to hepatitis B vaccination in adults with HIV-1.
    Lancet Infect Dis Volume: 12 Page(s): 966 - 976
    12/01/2012 Authors: Whitaker JA; Rouphael NG; Edupuganti S; Lai L; Mulligan MJ
  • Immunogenicity and safety of varying dosages of a monovalent 2009 H1N1 influenza vaccine given with and without AS03 adjuvant system in healthy adults and older persons.
    J Infect Dis Volume: 206 Page(s): 811 - 820
    09/15/2012 Authors: Jackson LA; Chen WH; Stapleton JT; Dekker CL; Wald A; Brady RC; Edupuganti S; Winokur P; Mulligan MJ; Keyserling HL
  • Neisseria meningitidis: biology, microbiology, and epidemiology.
    Volume: 799 Page(s): 1 - 20
    01/01/2012 Authors: Rouphael NG; Stephens DS
  • Use of 2 pneumococcal common protein real-time polymerase chain reaction assays in healthy children colonized with Streptococcus pneumoniae.
    Diagn Microbiol Infect Dis Volume: 70 Page(s): 452 - 454
    08/01/2011 Authors: Rouphael N; Steyn S; Bangert M; Sampson JS; Adrian P; Madhi SA; Klugman KP; Ades EW
  • Fusarium falciforme vertebral abscess and osteomyelitis: case report and molecular classification.
    J Clin Microbiol Volume: 49 Page(s): 2350 - 2353
    06/01/2011 Authors: Edupuganti S; Rouphael N; Mehta A; Eaton M; Heller JG; Bressler A; Brandt M; O'Donnell K
  • Cytomegalovirus prostatitis in a heart transplant recipient.
    Am J Transplant Volume: 11 Page(s): 1330 - 1333
    06/01/2011 Authors: Rouphael NG; Laskar SR; Smith A; Lyon GM
  • Evaluation of serum bactericidal antibody assays for Haemophilus influenzae serotype a.
    Clin Vaccine Immunol Volume: 18 Page(s): 243 - 247
    02/01/2011 Authors: Rouphael NG; Satola S; Farley MM; Rudolph K; Schmidt DS; Gomez-de-Len P; Robbins JB; Schneerson R; Carlone GM; Romero-Steiner S
  • Aspergillus endocarditis: a review of the literature.
    Int J Infect Dis Volume: 14 Page(s): e1040 - e1047
    12/01/2010 Authors: Kalokhe AS; Rouphael N; El Chami MF; Workowski KA; Ganesh G; Jacob JT
  • Viral infections associated with haemophagocytic syndrome.
    Rev Med Virol Volume: 20 Page(s): 93 - 105
    03/01/2010 Authors: Maakaroun NR; Moanna A; Jacob JT; Albrecht H
  • Case report: atypical Lemierre's disease secondary to Porphyromonas asaccharolytica.
    Curr Opin Pediatr Volume: 21 Page(s): 397 - 400
    06/01/2009 Authors: Sharma D; Rouphael N
  • A real-time polymerase chain reaction for the detection of Streptococcus pneumoniae in blood using a mouse model: a potential new "gold standard".
    Diagn Microbiol Infect Dis Volume: 62 Page(s): 23 - 25
    09/01/2008 Authors: Rouphael NG; Atwell-Melnick N; Longo D; Whaley M; Carlone GM; Sampson JS; Ades EW
  • Evolution.
    Am J Med Volume: 121 Page(s): 583 - 585
    07/01/2008 Authors: Talati NJ; Rouphael NG
  • Pleural effusion in a patient with AIDS.
    Clin Infect Dis Volume: 46 Page(s): 1887 - 1927
    06/15/2008 Authors: Cartwright E; Rouphael N; Jain S; Ilksoy N
  • Spectrum of CNS disease caused by rapidly growing mycobacteria.
    Lancet Infect Dis Volume: 8 Page(s): 390 - 398
    06/01/2008 Authors: Talati NJ; Rouphael N; Kuppalli K; Franco-Paredes C
  • Clostridium difficile-associated diarrhea: an emerging threat to pregnant women.
    Am J Obstet Gynecol Volume: 198 Page(s): 635.e1 - 635.e6
    06/01/2008 Authors: Rouphael NG; O'Donnell JA; Bhatnagar J; Lewis F; Polgreen PM; Beekmann S; Guarner J; Killgore GE; Coffman B; Campbell J
  • Proof of utility for real-time polymerase chain reaction in the diagnosis of Streptococcus pneumoniae bacteremia using a murine bacteremia model
    Volume: 56 Page(s): 474 - 474
    01/01/2008 Authors: Rouphael NG; Melnick NA; Longo D; Whaley M; Carlone G; Sampson J; Ades E
  • Infections associated with haemophagocytic syndrome.
    Lancet Infect Dis Volume: 7 Page(s): 814 - 822
    12/01/2007 Authors: Rouphael NG; Talati NJ; Vaughan C; Cunningham K; Moreira R; Gould C
  • A painful thorn in the foot: a case of eumycetoma.
    Am J Med Sci Volume: 334 Page(s): 142 - 144
    08/01/2007 Authors: Rouphael NG; Talati NJ; Franco-Paredes C
  • Cardiac manifestations of parasitic infections part 3: pericardial and miscellaneous cardiopulmonary manifestations.
    Clin Cardiol Volume: 30 Page(s): 277 - 280
    06/01/2007 Authors: Franco-Paredes C; Rouphael N; Mndez J; Folch E; Rodrguez-Morales AJ; Santos JI; Hurst JW
  • Cardiac manifestations of parasitic infections. Part 2: Parasitic myocardial disease.
    Clin Cardiol Volume: 30 Page(s): 218 - 222
    05/01/2007 Authors: Franco-Paredes C; Rouphael N; Mndez J; Folch E; Rodrguez-Morales AJ; Santos JI; Hurst JW
  • Cardiac manifestations of parasitic infections part 1: overview and immunopathogenesis.
    Clin Cardiol Volume: 30 Page(s): 195 - 199
    04/01/2007 Authors: Franco-Paredes C; Rouphael N; Mndez J; Folch E; Rodrguez-Morales AJ; Santos JI; Hurst JW
  • Hepatitis B reverse seroconversion in HIV-positive patients: case series and review of the literature.
    AIDS Volume: 21 Page(s): 771 - 774
    03/30/2007 Authors: Rouphael NG; Talati NJ; Rimland D
  • Polymyxin B and doxycycline use in patients with multidrug-resistant Acinetobacter baumannii infections in the intensive care unit.
    Ann Pharmacother Volume: 40 Page(s): 1939 - 1945
    11/01/2006 Authors: Holloway KP; Rouphael NG; Wells JB; King MD; Blumberg HM
  • Vaccination strategies to prevent tuberculosis in the new millennium: from BCG to new vaccine candidates.
    Int J Infect Dis Volume: 10 Page(s): 93 - 102
    03/01/2006 Authors: Franco-Paredes C; Rouphael N; del Rio C; Santos-Preciado JI
  • Skin ulcers misdiagnosed as pyoderma gangrenosum.
    N Engl J Med Volume: 348 Page(s): 1064 - 1066
    03/13/2003 Authors: Rouphael NG; Ayoub NM; Tomb RR
  • Characterization of flares in patients with systemic lupus erythematosus: comment on the article by Ho et al.
    Arthritis Rheum Volume: 48 Page(s): 581 - 582
    02/01/2003 Authors: Ayoub N; Ayoub G; Rouphael N
  • [Hirsutism].
    Ann Dermatol Venereol Volume: 129 Page(s): 1140 - 1150
    10/01/2002 Authors: Ayoub N; Rouphael N; Tomb R
  • "Bazex syndromes": dissimilar entities named after the same father!
    Urology Volume: 59 Page(s): 463
    03/01/2002 Authors: Ayoub N; Rouphael N; Stephan F
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