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Profile

Nicholas Maurice M.D.

  • Department of Medicine
    Assistant Professor
  • (404) 321-6111
  • nicholas.michael.maurice@emory.edu
Head shot of Nicholas Maurice

Overview

Dr. Nicholas Maurice received his undergraduate degree at the University of Notre Dame in 2007. He earned his medical degree at the University of Pittsburgh School of Medicine in 2012 after additional research training in the Physician Scientist Training Program and as a Howard Hughes Medical Institute (HHMI) Medical Research Fellow. He completed Internal Medicine internship and residency at the University of Michigan Health System in 2015. He then completed his Pulmonary and Critical Care Medicine fellowship at Emory University in 2019 after completing a post-doctoral research fellowship under the mentorship of Dr. Ruxana Sadikot. He thereafter joined the faculty as an Assistant Professor of Medicine. He earned a Research Development Award (RDA) from the Department of Veterans Affairs in 2019 and a national Career Development Award (CDA-2) in 2022. He conducts laboratory research investigating the lung epithelial host response to bacterial pneumonia and investigates possible therapeutic approaches to augment this host response to bacterial pathogens. He practices clinical pulmonary and critical care medicine at the Atlanta VA Health Care System (AVAHCS), where he also serves as Director of the AVAHCS Lung Cancer Screening program, served as the site director for the VA Partnership to Increase Access to Lung Cancer Screening (VA-PALS) program, and serves as a co-Investigator within the VA Lung Precision Oncology Program (LPOP) VISN7 Southeastern .Consortium.

Academic Appointment

  • Assistant Professor of Medicine, Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University School of Medicine

Education

Degrees

  • M.D. from University of Pittsburgh School of Medicine
  • B.S. from University of Notre Dame

Research

Publications

  • Health Care Provider Practices and Perceptions of Biomarker Testing in US Veterans With Non-Small Cell Lung Cancer.
    Chest Volume: 167 Page(s): 630 - 635
    02/01/2025 Authors: Vlachos E; Fox A; Dell'Italia J; Maurice N; Rubinstein I; Tanner NT
  • Mitochondrial Dysfunction in Bacterial Infections.
    Pathogens Volume: 12
    08/01/2023 Authors: Maurice NM; Sadikot RT
  • Lung cancer screening at the VA: Past, present and future.
    Semin Oncol Volume: 49 Page(s): 206 - 212
    06/01/2022 Authors: Maurice NM; Tanner NT
  • The Effect of PGC-1alpha-SIRT3 Pathway Activation on Pseudomonas aeruginosa Infection.
    Pathogens Volume: 11
    01/01/2023 Authors: Maurice NM; Bedi B; Yuan Z; Lin K-C; Goldberg JB; Hart CM; Bailey KL; Sadikot RT
  • Oxidative Mitochondrial DNA Damage in Lung Epithelial Cells Induced by Non-Pore-Forming Action of the Pneumococcal Virulence Factor Pneumolysin
    Volume: 203
    05/01/2021 Authors: Maurice NM; Bedi B; Yuan Z; Koval M; Vidal JE; Hart C; Sadikot RT
  • UPR modulation of host immunity by Pseudomonas aeruginosa in cystic fibrosis.
    Clin Sci (Lond) Volume: 134 Page(s): 1911 - 1934
    07/31/2020 Authors: Bedi B; Lin K-C; Maurice NM; Yuan Z; Bijli K; Koval M; Hart CM; Goldberg JB; Stecenko A; Sadikot RT
  • STREPTOCOCCUS PNEUMONIAE-INDUCED EPITHELIAL BARRIER FUNCTION IS MEDIATED BY MITOCHONDRIAL REACTIVE OXYGEN SPECIES GENERATION AND ATTENUATED BY A MITOCHONDRIALLY-TARGETED ANTIOXIDANT
    Volume: 68 Page(s): 603 - 603
    02/01/2020 Authors: Maurice NM; Bedi B; Yuan Z; Koval M; Hart M; Sadikot RT
  • UPR Induced Modulation of Host Defense by P. Aeruginosa in Cystic Fibrosis
    Volume: 201
    01/01/2020 Authors: Bedi B; Lin K; Maurice NM; Goldberg JB; Stecenko AA; Sadikot RT
  • Streptococcus Pneumoniae-Induced Epithelial Barrier Dysfunction Is Mediated by Mitochondrial Reactive Oxygen Species Generation and Attenuated by a Mitochondrially-Targeted Antioxidant
    Volume: 201
    01/01/2020 Authors: Maurice NM; Bedi B; Yuan Z; Koval M; Hart C; Sadikot RT
  • Pseudomonas aeruginosa Induced Host Epithelial Cell Mitochondrial Dysfunction.
    Sci Rep Volume: 9 Page(s): 11929
    08/15/2019 Authors: Maurice NM; Bedi B; Yuan Z; Goldberg JB; Koval M; Hart CM; Sadikot RT
  • Pseudomonas aeruginosa accentuates inflammatory responses under HIV infection through TREM-1 activation
    Volume: 33
    04/01/2019 Authors: Yuan Z; Fan X; Maurice NM; Bedi B; Guidot DM; Sadikot RT
  • Mitochondrial DNA damage associated activation of NLRP3 inflammasome impairs host defense during P. aeruginosa infection
    Volume: 33
    04/01/2019 Authors: Bedi B; Maurice NM; Yuan Z; Prasla Z; Sadikot RT
  • PSEUDOMONAS AERUGINOSA INFECTION ATTENUATES EXPRESSION OF CRITICAL GENES RESPONSIBLE FOR MITOCHONDRIAL BIOGENESIS AND ANTI-OXIDANT DEFENSE IN THE LUNG EPITHELIUM
    Volume: 67 Page(s): 613 - 613
    02/01/2019 Authors: Maurice NM; Bedi B; Goldberg JB; Hart M; Sadikot RT
  • Pseudomonas Aeruginosa Infection Attenuates Expression of Critical Genes Responsible for Mitochondrial Biogenesis and Anti-Oxidant Defense in Murine Model of Acute Pneumonia
    Volume: 199
    01/01/2019 Authors: Maurice NM; Bedi B; Yuan Z; Goldberg JB; Hart C; Sadikot RT
  • Pseudomonas aeruginosa Biofilms: Host Response and Clinical Implications in Lung Infections.
    Am J Respir Cell Mol Biol Volume: 58 Page(s): 428 - 439
    04/01/2018 Authors: Maurice NM; Bedi B; Sadikot RT
  • PSEUDOMONAS AERUGINOSA QUORUM SENSING MOLECULE-INDUCED MITOCHONDRIAL DAMAGE, OXIDATIVE STRESS AND EPITHELIAL BARRIER DYSFUNCTION IS RESCUED BY PHARMACOLOGIC ACTIVATION OF PPARg COACTIVATOR 1-ALPHA (PGC1-alpha)
    Volume: 66 Page(s): 597 - 597
    02/01/2018 Authors: Maurice NM; Bedi B; Yuan Z; Goldberg JB; Hart M; Sadikot RT
  • Exosomal Micro RNAs Shuttling from HIV Viral Protein-Treated Macrophages Disrupt Tight Junction Barrier Integrity and Mitochondrial Biogenesis of Alveolar Epithelial Cells
    Volume: 197
    01/01/2018 Authors: Yuan Z; Fan X; Maurice NM; Bedi B; Guidot DM; Sadikot RT
  • Cystic Fibrosis Variants of P. Aeruginosa Attenuate Host PPARgamma Expression in Epithelial Cells and Macrophages
    Volume: 197
    01/01/2018 Authors: Bedi B; Maurice NM; Bijli KM; Yuan Z; Varga JJ; Wenjing J; Goldberg JB; Stecenko AA; Hart C; Sadikot RT
  • Pseudomonas Aeruginosa Quorum Sensing Molecule-Induced Mitochondrial Damage, Oxidative Stress and Epithelial Barrier Dysfunction Is Rescued by Overexpression and Pharmacologic Activation of Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-Alpha (PGC1-alpha)
    Volume: 197
    01/01/2018 Authors: Maurice NM; Bedi B; Yuan Z; Goldberg JB; Hart C; Sadikot RT
  • Peroxisome proliferator-activated receptor- agonists attenuate biofilm formation by Pseudomonas aeruginosa.
    FASEB J Volume: 31 Page(s): 3608 - 3621
    08/01/2017 Authors: Bedi B; Maurice NM; Ciavatta VT; Lynn KS; Yuan Z; Molina SA; Joo M; Tyor WR; Goldberg JB; Koval M
  • PSEUDOMONAS AERUGINOSA QUORUM SENSING MOLECULES ATTENUATE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) GAMMA AND PPAR GAMMA COACTIVATOR 1 (PGC1)-ALPHA, AND SUPPRESS EPITHELIAL MITOCHONDRIAL RESPIRATION
    Volume: 65 Page(s): 617 - 617
    02/01/2017 Authors: Maurice NM; Bedi B; Varga JJ; Yuan Z; Goldberg JB; Hart M; Sadikot RT
  • Ppar gamma Agonists Attenuate Biofilm Formation By Pseudomonas AerugINOSa
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 195
    01/01/2017 Authors: Bedi B; Maurice NM; Ciavatta VT; Tyor WR; Yuan Z; Goldberg JB; Hart CM; Koval MH; Sadikot RT
  • Pseudomonas AerugINOSa Quorum Sensing Molecules Attenuate Peroxisome Proliferator-Activated Receptor Gamma (ppar gamma) And Ppar gamma Coactivator 1-Alpha (pgc1-alpha), And Suppress Epithelial Mitochondrial Respiration
    Volume: 195
    01/01/2017 Authors: Maurice NM; Bedi B; Varga J; Yuan Z; Goldberg JB; Hart CM; Sadikot RT
  • Novel treatment strategies for liver disease due to 1-antitrypsin deficiency.
    Clin Transl Sci Volume: 5 Page(s): 289 - 294
    06/01/2012 Authors: Maurice N; Perlmutter DH
  • An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis.
    Science Volume: 329 Page(s): 229 - 232
    07/09/2010 Authors: Hidvegi T; Ewing M; Hale P; Dippold C; Beckett C; Kemp C; Maurice N; Mukherjee A; Goldbach C; Watkins S
  • Caspase inhibition blocks cell death and results in cell cycle arrest in cytokine-deprived hematopoietic cells.
    J Biol Chem Volume: 282 Page(s): 2144 - 2155
    01/26/2007 Authors: Brown NM; Martin SM; Maurice N; Kuwana T; Knudson CM
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