Nael McCarty PhD

Department of Pediatrics
Professor

(404) 727-3654
namccar@emory.edu

Academic Appointment

Marcus Professor of Cystic Fibrosis, Department of Pediatrics, PACS Division, Emory University School of Medicine
Associate Chief for Research, Division of Pulmonology, Allergy/Immunology, Cystic Fibrosis, and Sleep, Emory University School of Medicine
Adjunct Assoc. Prof. of Biology, Georgia Inst. of Tech
Adjunct Assoc. Prof. of Chemistry & Biochemistry, Georgia Inst. of Tech
Adjunct Assoc. Prof. of Applied Physiology, Georgia Inst. of Tech
Adjunct Assoc. Prof. of Physiology, Emory University School of Medicine

Education

Degrees

PhD from University of TX Health Science Center at Houston
M.S. from University of North Carolina at Wilmington
BS from University of Kansas

Research

Focus

In the McCarty lab, we focus on the molecular physiology of ion channels and receptors, with emphasis on epithelial chloride channels. Our specific focus is the pathophysiology of Cystic Fibrosis, including the structure/function of CFTR and its many roles in the airway. We pioneered the use of peptide toxins as probes of chloride channels.

Publications

Effects of hyperglycemia on airway epithelial barrier function in WT and CF 16HBE cells.
Sci Rep Volume: 14 Page(s): 25095
10/23/2024 Authors: Vazquez Cegla AJ; Jones KT; Cui G; Cottrill KA; Koval M; McCarty NA
Flagellum-deficient Pseudomonas aeruginosa is more virulent than non-motile but flagellated mutants in a cystic fibrosis mouse model.
Microbiol Spectr Volume: 12 Page(s): e0132524
10/03/2024 Authors: Moustafa DA; Fantone KM; Tucker SL; McCarty NA; Stecenko AA; Goldberg JB; Rada B
Chronic hyperglycemia aggravates lung function in a Scnn1b-Tg murine model.
Am J Physiol Lung Cell Mol Physiol Volume: 327 Page(s): L473 - L486
10/01/2024 Authors: Cui G; Moustafa DA; Zhao S; Cegla AV; Lyles JT; Goldberg JB; Chandler JD; McCarty NA
Development of a programmable automated cell culture system to study the lung pathophysiology of Cystic Fibrosis-related diabetes.
Heliyon Volume: 10 Page(s): e37977
09/30/2024 Authors: Vazquez Cegla AJ; Hedden C; Imhoff BR; Cui G; McCarty NA
Comparing ATPase activity of ATP-binding cassette subfamily C member 4, lamprey CFTR, and human CFTR using an antimony-phosphomolybdate assay.
Front Pharmacol Volume: 15 Page(s): 1363456
01/01/2024 Authors: Cui G; Strickland KM; Vazquez Cegla AJ; McCarty NA
A transistor model for the cystic fibrosis transmembrane conductance regulator.
Biophys Rep (N Y) Volume: 3 Page(s): 100108
06/14/2023 Authors: Hunt WD; McCarty NA; Marin EM; Westafer RS; Yamin PR; Cui G; Eckford AW; Denison DR
Tweaking the catalytic efficiency of the CFTR ion channel.
J Gen Physiol Volume: 155
05/01/2023 Authors: McCarty NA
Mathematical models of cystic fibrosis as a systemic disease.
WIREs Mech Dis Volume: 15 Page(s): e1625
01/01/2023 Authors: Olivena DV; Davis JD; Kumbale CM; Zhao CY; Brown SP; McCarty NA; Voit EO
Exacerbation-prone pediatric asthma is associated with arginine, lysine, and methionine pathway alterations.
J Allergy Clin Immunol Volume: 151 Page(s): 118 - 127.e10
01/01/2023 Authors: Cottrill KA; Stephenson ST; Mohammad AF; Kim SO; McCarty NA; Kamaleswaran R; Fitzpatrick AM; Chandler JD
Permissive and nonpermissive channel closings inCFTR revealed by a factor graph inference algorithm.
Biophys Rep (N Y) Volume: 2 Page(s): 100083
12/14/2022 Authors: Moffett AS; Cui G; Thomas PJ; Hunt WD; McCarty NA; Westafer RS; Eckford AW
Bacteriophage-Loaded Poly(lactic-co-glycolic acid) Microparticles Mitigate Staphylococcus aureus Infection and Cocultures of Staphylococcus aureus and Pseudomonas aeruginosa.
Adv Healthc Mater Volume: 11 Page(s): e2102539
05/01/2022 Authors: Kalelkar PP; Moustafa DA; Riddick M; Goldberg JB; McCarty NA; Garca AJ
The molecular evolution of function in the CFTR chloride channel.
J Gen Physiol Volume: 153
12/06/2021 Authors: Infield DT; Strickland KM; Gaggar A; McCarty NA
Mechanistic analysis and significance of sphingomyelinase-mediated decreases in transepithelial CFTR currents in nHBEs.
Physiol Rep Volume: 9 Page(s): e15023
09/01/2021 Authors: Cottrill KA; Giacalone VD; Margaroli C; Bridges RJ; Koval M; Tirouvanziam R; McCarty NA
Sphingomyelinase decreases transepithelial anion secretion in airway epithelial cells in part by inhibiting CFTR-mediated apical conductance.
Physiol Rep Volume: 9 Page(s): e14928
08/01/2021 Authors: Cottrill KA; Peterson RJ; Lewallen CF; Koval M; Bridges RJ; McCarty NA
Breathe-Your immune system is counting on it.
J Exp Med Volume: 218
04/05/2021 Authors: McCarty NA
Reconstitution of Detergent-Solubilized Membrane Proteins into Proteoliposomes and Nanodiscs for Functional and Structural Studies.
Methods Mol Biol Volume: 2302 Page(s): 21 - 35
01/01/2021 Authors: Strickland KM; Neselu K; Grant AJ; Espy CL; McCarty NA; Schmidt-Krey I
Alteration of Membrane Cholesterol Content Plays a Key Role in Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Channel Activity.
Front Physiol Volume: 12 Page(s): 652513
01/01/2021 Authors: Cui G; Cottrill KA; Strickland KM; Mashburn SA; Koval M; McCarty NA
Electrophysiological Approaches for the Study of Ion Channel Function.
Methods Mol Biol Volume: 2302 Page(s): 49 - 67
01/01/2021 Authors: Cui G; Cottrill KA; McCarty NA
BASOLATERAL SMASE INHIBITS THE APICAL CFTR CHANNEL IN PRIMARY BRONCHIAL EPITHELIAL CELLS
Volume: 55 Page(s): S71 - S72
10/01/2020 Authors: Cottrill KA; Koval M; Bridges RJ; McCarty NA
HYPERGLYCEMIC CONDITIONS DYSREGULATE BARRIER AND CHANNEL FUNCTION IN HUMAN CYSTIC FIBROSIS BRONCHIAL EPITHELIA
Volume: 55 Page(s): S47 - S47
10/01/2020 Authors: Cui G; Cottrill KA; Strickland K; Mashburn SA; Koval M; McCarty NA
The bidirectional relationship between CFTR and lipids.
Commun Biol Volume: 3 Page(s): 179
04/20/2020 Authors: Cottrill KA; Farinha CM; McCarty NA
Comparing Lipid and Detergent Environment as Models for Studying Renal Transmembrane Proteins
Volume: 34
04/01/2020 Authors: Pavkov I; Strickland K; Cottrill K; Imhoff B; McCarty N
Determining the Lipid Environment and Interactions of CFTR
Volume: 118 Page(s): 239A - 239A
02/07/2020 Authors: Cottrill K; Strickland KM; McCarty NA
Alteration of Membrane Cholesterol Content Plays a Key Role in Regulation of CFTR Channel Activity
Volume: 118 Page(s): 588A - 588A
02/07/2020 Authors: Cui G; Cottrill KA; Strickland KM; Imhoff BR; McCarty NA
Early Detection of Cystic Fibrosis Acute Pulmonary Exacerbations by Exhaled Breath Condensate Metabolomics.
J Proteome Res Volume: 19 Page(s): 144 - 152
01/03/2020 Authors: Zang X; Monge ME; Gaul DA; McCarty NA; Stecenko A; Fernndez FM
An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters.
Dev Cell Volume: 51 Page(s): 421 - 430.e3
11/18/2019 Authors: Cui G; Hong J; Chung-Davidson Y-W; Infield D; Xu X; Li J; Simhaev L; Khazanov N; Stauffer B; Imhoff B
CERAMIDE INHIBITS CFTR CURRENT IN PRIMARY BRONCHIAL EPITHELIAL CELLS
Volume: 54 Page(s): S194 - S194
10/01/2019 Authors: Cottrill KA; McCarty NA
TOWARDS INVESTIGATING THE LIPID ENVIRONMENT OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
Volume: 54 Page(s): S186 - S186
10/01/2019 Authors: Strickland K; Cottrill KA; Schmidt-Krey I; McCarty NA
HUMAN CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CHANNEL FUNCTION IS REGULATED BY CHOLESTEROL
Volume: 54 Page(s): S202 - S202
10/01/2019 Authors: Cui G; Cottrill KA; Strickland K; Imhoff B; McCarty NA
LAMPREY CFTR: AN ANCIENT CFTR ORTHOLOG INFORMS MOLECULAR EVOLUTION IN ABC TRANSPORTERS
Volume: 54 Page(s): S195 - S195
10/01/2019 Authors: Cui G; Hong JS; Chung-Davidson Y; Infield D; Xu X; Simhaev L; Khazanov N; Stauffer BB; Imhoff B; Cottrill KA
VX-770-mediated potentiation of numerous human CFTR disease mutants is influenced by phosphorylation level.
Sci Rep Volume: 9 Page(s): 13460
09/17/2019 Authors: Cui G; Stauffer BB; Imhoff BR; Rab A; Hong JS; Sorscher EJ; McCarty NA
ATP-Dependent Signaling in Simulations of a Revised Model of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).
J Phys Chem B Volume: 123 Page(s): 3177 - 3188
04/18/2019 Authors: Strickland KM; Stock G; Cui G; Hwang H; Infield DT; Schmidt-Krey I; McCarty NA; Gumbart JC
Effects of Lipid and Detergent Environments on Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Function and Structure
Volume: 116 Page(s): 222A - 222A
02/15/2019 Authors: Strickland KM; Stauffer BB; Uddin YM; Imhoff BR; Schmidt-Krey I; McCarty NA
Determining the Mechanism of SMase-Mediated Inhibition of CFTR Current in Primary Bronchial Epithelial Cells
Volume: 116 Page(s): 222A - 223A
02/15/2019 Authors: Cottrill KA; Stauffer BB; McCarty NA
Human CFTR Channel Function is Regulated by Cholesterol
Volume: 116 Page(s): 249A - 249A
02/15/2019 Authors: Cui G; Cottrill KA; McGill KA; Imhoff B; McCarty NA
Inhaled bacteriophage-loaded polymeric microparticles ameliorate acute lung infections.
Nat Biomed Eng Volume: 2 Page(s): 841 - 849
11/01/2018 Authors: Agarwal R; Johnson CT; Imhoff BR; Donlan RM; McCarty NA; Garca AJ
DETERMINING THE MECHANISM OF SMASE-MEDIATED INHIBITION OF CHLORIDE CURRENT IN BRONCHIAL EPITHELIAL CELLS
Volume: 53 Page(s): 168 - 168
09/01/2018 Authors: Cottrill KA; Stauffer B; Imhoff B; McCarty NA
EFFECTS OF LIPID ENVIRONMENT ON THE STRUCTURE AND FUNCTION OF CFTR
Volume: 53 Page(s): 165 - 165
09/01/2018 Authors: Strickland K; Stauffer B; Imhoff B; McCarty NA; Schmidt-Krey I
CFTR PHOSPHORYLATION LEVEL MODULATES THE EFFICACY OF VX-770-MEDIATED POTENTIATION OF NUMEROUS HUMAN CFTR DISEASE-ASSOCIATED VARIANTS
Volume: 53 Page(s): 110 - 111
09/01/2018 Authors: Cui G; Stauffer BB; Imhoff B; Rab A; Hong JS; Sorscher EJ; McCarty NA
Protein and lipid interactions - Modulating CFTR trafficking and rescue.
J Cyst Fibros Volume: 17 Page(s): S9 - S13
03/01/2018 Authors: Farinha CM; Miller E; McCarty N
Zebrafish aversive taste co-receptor is expressed in both chemo- and mechanosensory cells and plays a role in lateral line development.
Sci Rep Volume: 7 Page(s): 13475
10/18/2017 Authors: Mojib N; Xu J; Bartolek Z; Imhoff B; McCarty NA; Shin CH; Kubanek J
LAMPREY CFTR, AN EVOLUTIONARY ANCESTOR OF HUMAN CFTR, EXHIBITS NUMEROUS BIOPHYSICAL DISSIMILARITIES FROM HUMAN CFTR
Volume: 52 Page(s): S224 - S224
09/01/2017 Authors: Cui G; Hong JS; Stauffer B; Imhoff BR; Gaggar A; McCarty NA
PHENOTYPE AND GLUCOSE UTILIZATION CHARACTERISTICS OF CONDITIONALLY REPROGRAMMED PRIMARY HUMAN AIRWAY EPITHELIA
PEDIATRIC PULMONOLOGY Volume: 52 Page(s): S253 - S253
09/01/2017 Authors: Molina SA; Vance RJ; McCarty NA; Koval M
Molecular Dynamics Flexible Fitting Simulations Identify New Models of the Closed State of the Cystic Fibrosis Transmembrane Conductance Regulator Protein.
J Chem Inf Model Volume: 57 Page(s): 1932 - 1946
08/28/2017 Authors: Simhaev L; McCarty NA; Ford RC; Senderowitz H
Comparison of Ambient and Atmospheric Pressure Ion Sources for Cystic Fibrosis Exhaled Breath Condensate Ion Mobility-Mass Spectrometry Metabolomics.
J Am Soc Mass Spectrom Volume: 28 Page(s): 1489 - 1496
08/01/2017 Authors: Zang X; Prez JJ; Jones CM; Monge ME; McCarty NA; Stecenko AA; Fernndez FM
Bacterial Sphingomyelinase is a State-Dependent Inhibitor of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR).
Sci Rep Volume: 7 Page(s): 2931
06/07/2017 Authors: Stauffer BB; Cui G; Cottrill KA; Infield DT; McCarty NA
Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner.
Am J Physiol Lung Cell Mol Physiol Volume: 312 Page(s): L688 - L702
01/01/2017 Authors: Molina SA; Moriarty HK; Infield DT; Imhoff BR; Vance RJ; Kim AH; Hansen JM; Hunt WR; Koval M; McCarty NA
Feasibility of Early Detection of Cystic Fibrosis Acute Pulmonary Exacerbations by Exhaled Breath Condensate Metabolomics: A Pilot Study.
J Proteome Res Volume: 16 Page(s): 550 - 558
02/03/2017 Authors: Zang X; Monge ME; McCarty NA; Stecenko AA; Fernndez FM
Correction: The "new normal": Adapting doctoral trainee career preparation for broad career paths in science.
PLoS One Volume: 12 Page(s): e0181294
01/01/2017 Authors: St Clair R; Hutto T; MacBeth C; Newstetter W; McCarty NA; Melkers J
The "new normal": Adapting doctoral trainee career preparation for broad career paths in science.
PLoS One Volume: 12 Page(s): e0177035
01/01/2017 Authors: St Clair R; Hutto T; MacBeth C; Newstetter W; McCarty NA; Melkers J
NOVEL POTENTIATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR IDENTIFIED WITH PHARMACOPHORE MODELING AND EXPERIMENTAL SCREENING
PEDIATRIC PULMONOLOGY Volume: 51 Page(s): 203 - 203
10/01/2016 Authors: Cui G; Khazanov N; Imhoff B; Senderowitz H; McCarty NA
ACTIVATION OF AKT SIGNALING IN HUMAN AIRWAY CELLS EXPRESSING MUTANT CFTR DIFFERS COMPARED TO WILD-TYPE
PEDIATRIC PULMONOLOGY Volume: 51 Page(s): 242 - 242
10/01/2016 Authors: Molina SA; Vance RJ; Imhoff B; McCarty NA; Koval M
Advanced glycation end products are elevated in cystic fibrosis-related diabetes and correlate with worse lung function.
J Cyst Fibros Volume: 15 Page(s): 681 - 688
09/01/2016 Authors: Hunt WR; Helfman BR; McCarty NA; Hansen JM
Potentiators exert distinct effects on human, murine, and Xenopus CFTR.
Am J Physiol Lung Cell Mol Physiol Volume: 311 Page(s): L192 - L207
08/01/2016 Authors: Cui G; Khazanov N; Stauffer BB; Infield DT; Imhoff BR; Senderowitz H; McCarty NA
A longitudinal analysis of chronic MRSA and Pseudomonas aeruginosa co-infection in cystic fibrosis: A single-center study.
J Cyst Fibros Volume: 15 Page(s): 350 - 356
05/01/2016 Authors: Maliniak ML; Stecenko AA; McCarty NA
Positioning of extracellular loop 1 affects pore gating of the cystic fibrosis transmembrane conductance regulator.
Am J Physiol Lung Cell Mol Physiol Volume: 310 Page(s): L403 - L414
03/01/2016 Authors: Infield DT; Cui G; Kuang C; McCarty NA
Refinement of a Recent CFTR Homology Model Guided by Pore Formation
Volume: 110 Page(s): 140A - 141A
02/16/2016 Authors: Stock G; McCarty N; Gumbart JC
CFTR Potentiators Exert Different Effects on Human, Murine, and Xenopus CFTR
Volume: 110 Page(s): 452A - 452A
02/16/2016 Authors: Cui G; Khazanov N; Stauffer BB; Infield DT; Imhoff BR; Senderowitz H; McCarty NA
Ability of device to collect bacteria from cough aerosols generated by adults with cystic fibrosis.
F1000Res Volume: 5 Page(s): 1920
01/01/2016 Authors: Ku DN; Ku SK; Helfman B; McCarty NA; Wolff BJ; Winchell JM; Anderson LJ
Murine and human CFTR exhibit different sensitivities to CFTR potentiators.
Am J Physiol Lung Cell Mol Physiol Volume: 309 Page(s): L687 - L699
10/01/2015 Authors: Cui G; McCarty NA
INSULIN IMPAIRS AIRWAY BARRIER FUNCTION IN CYSTIC FIBROSIS RELATED DIABETES
PEDIATRIC PULMONOLOGY Volume: 50 Page(s): 246 - 246
10/01/2015 Authors: Molina SA; Moriarty HK; Kim AH; McCarty NA; Koval M
FEASIBILITY OF EARLY DETECTION OF ACUTE PULMONARY EXACERBATIONS BY BREATHOMICS
PEDIATRIC PULMONOLOGY Volume: 50 Page(s): 348 - 349
10/01/2015 Authors: Zang X; Monge ME; McCarty NA; Stecenko A; Fernandez F
PHOSPHORYLATION SITES IN THE R DOMAIN IN MURINE CFTR EXHIBIT POWERFUL INHIBITORY FUNCTIONS ON CHANNEL ACTIVATION
PEDIATRIC PULMONOLOGY Volume: 50 Page(s): 207 - 207
10/01/2015 Authors: Cui G; Imhoff BR; McCarty NA
COMPARATIVE MOLECULAR PHARMACOLOGY OF CFTR: TOWARD THE IDENTIFICATION OF NOVEL POTENTIATORS AND THEIR BINDING SITES
PEDIATRIC PULMONOLOGY Volume: 50 Page(s): 208 - 208
10/01/2015 Authors: Cui G; Khazanov N; Senderowitz H; McCarty NA
ATOMISTIC SIMULATIONS VALIDATING A RECENT CFTR HOMOLOGY MODEL
PEDIATRIC PULMONOLOGY Volume: 50 Page(s): 209 - 209
10/01/2015 Authors: Stock G; McCarty NA; Gumbart J
MOLECULAR DYNAMICS FLEXIBLE FITTING (MDFF) SIMULATIONS IDENTIFY MODELS OF CLOSE-STATE CFTR
PEDIATRIC PULMONOLOGY Volume: 50 Page(s): 201 - 201
10/01/2015 Authors: Simchaev L; McCarty NA; Ford B; Senderowitz H
Junctional abnormalities in human airway epithelial cells expressing F508del CFTR.
Am J Physiol Lung Cell Mol Physiol Volume: 309 Page(s): L475 - L487
09/01/2015 Authors: Molina SA; Stauffer B; Moriarty HK; Kim AH; McCarty NA; Koval M
Aversive chemoreception in predatory fish
Volume: 55 Page(s): E115 - E115
04/01/2015 Authors: Lunceford BE; Cohen PS; Bloomquist R; Nagle MP; Shin C; Mccarty NA; Kubanek J
Positioning of the First Extracellular Loop of CFTR Has Significant Effects on CFTR Gating
Volume: 108 Page(s): 441A - 441A
01/27/2015 Authors: Infield DT; Cui G; Kuang C; McCarty NA
Inhibition of the CFTR Chloride Channel by Sphingomyelinase
Volume: 108 Page(s): 435A - 435A
01/27/2015 Authors: Stauffer B; Cui G; Infield DT; McCarty N
Refinement and Evaluation of a CFTR Homology Model and Identification of Residues Controlling Channel Gating
BIOPHYSICAL JOURNAL Volume: 108 Page(s): 127A - 127A
01/27/2015 Authors: Stock G; Cui G; McCarty NA; Gumbart JC
Alpha-type Cx43 function is restored with 4-PBA treatment in Cystic Fibrosis airway epithelial cells that express misfolded F508del-CFTR protein
MOLECULAR BIOLOGY OF THE CELL Volume: 26
01/01/2015 Authors: Molina SA; McCarty NA; Koval M
METABOLIC ANALYSIS OF EXHALED BREATH CONDENSATE IN CYSTIC FIBROSIS-RELATED DIABETES
PEDIATRIC PULMONOLOGY Volume: 49 Page(s): 424 - 424
09/31/2014 Authors: Hunt WR; Stecenko AA; Tran VT; McCarty NA; Jones DP; Hansen JM
IDENTIFICATION OF CHANGES IN LUNG MICROBIAL COMMUNITY COMPOSITION THAT CORRELATE WITH THE APPEARANCE OF ACUTE PULMONARY EXACERBATIONS
PEDIATRIC PULMONOLOGY Volume: 49 Page(s): 318 - 318
09/01/2014 Authors: Pena-Gonzalez A; Hatt JK; Helfman BR; McCarty NA; Konstantinidis K
HACK FOR CF, THE CYSTIC FIBROSIS HACKATHON
PEDIATRIC PULMONOLOGY Volume: 49 Page(s): 391 - 391
09/01/2014 Authors: McCarty NA; Geyer R; Allen T; Gardner A; Carter J; Bandyopadhyay R; Flanigan M; Walker P; Walker S; Henderson S
ADVANCED GLYCATION END PRODUCTS ARE ELEVATED IN CYSTIC FIBROSIS RELATED DIABETES
PEDIATRIC PULMONOLOGY Volume: 49 Page(s): 424 - 424
09/01/2014 Authors: Hunt WR; Helfman BR; McCarty NA; Hansen JM
CHRONIC MRSA AND P. AERUGINOSA CO-INFECTION AND LUNG FUNCTION DECLINE IN CYSTIC FIBROSIS
PEDIATRIC PULMONOLOGY Volume: 49 Page(s): 350 - 350
09/01/2014 Authors: Maliniak ML; McCarty NA; Stecenko AA; McClellan WM
MURINE CFTR BEHAVIOR DIFFERS FROM HUMAN CFTR IN DISTINCT ASPECTS
PEDIATRIC PULMONOLOGY Volume: 49 Page(s): 226 - 226
09/01/2014 Authors: Cui G; Prince C; McCarty NA
POSITIONING OF THE FIRST EXTRACELLULAR LOOP OF CFTR HAS SIGNIFICANT EFFECTS ON CFTR GATING
PEDIATRIC PULMONOLOGY Volume: 49 Page(s): 233 - 233
09/01/2014 Authors: Infield DT; Cui G; Kuang C; McCarty NA
FEASIBILITY OF EARLY DETECTION OF ACUTE PULMONARY EXACERBATIONS BY EXHALED BREATH CONDENSATE METABOLOMICS
PEDIATRIC PULMONOLOGY Volume: 49 Page(s): 367 - 368
09/01/2014 Authors: Fernandez F; Zang X; Monge M; McCarty NA; Stecenko AA
A MODEL OF LUNG INFECTION IN CFTR-/- MICE REVEALS ALTERED GENE EXPRESSION
PEDIATRIC PULMONOLOGY Volume: 49 Page(s): 418 - 418
09/01/2014 Authors: Freeman J; McCarty NA; Saul K; Kosters A
EXPRESSION PROFILING REVEALS THAT NULI AND CUFI AIRWAY EPITHELIAL CELL MATURATION REQUIRES EXTENDED TIME IN CULTURE
PEDIATRIC PULMONOLOGY Volume: 49 Page(s): 271 - 271
09/01/2014 Authors: Molina SA; Stauffer B; Hansen J; McCarty NA; Koval M
EXPRESSION OF Delta F508-CFTR BY AIRWAY EPITHELIAL CELLS SENSITIZES TIGHT JUNCTIONS TO GLUCOSE-INDUCED STRESS
PEDIATRIC PULMONOLOGY Volume: 49 Page(s): 263 - 263
09/01/2014 Authors: Schlingmann B; Molina SA; Hansen JM; Ziady AG; McCarty NA; Koval M
Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR.
J Gen Physiol Volume: 144 Page(s): 159 - 179
08/01/2014 Authors: Cui G; Rahman KS; Infield DT; Kuang C; Prince CZ; McCarty NA
Cross-talk between Connexin 43 and CFTR in ER quality control
FASEB JOURNAL Volume: 28
04/01/2014 Authors: Molina S; McCarty N; Koval M
ERp29 mediated cross-talk between Connexin43 and CFTR in ER quality control
ACTA PHYSIOLOGICA Volume: 210 Page(s): 80 - 80
03/01/2014 Authors: Molina S; McCarty N; Koval M
Hyperglycemia impedes lung bacterial clearance in a murine model of cystic fibrosis-related diabetes.
Am J Physiol Lung Cell Mol Physiol Volume: 306 Page(s): L43 - L49
01/01/2014 Authors: Hunt WR; Zughaier SM; Guentert DE; Shenep MA; Koval M; McCarty NA; Hansen JM
Inflammation and ER stress downregulate BDH2 expression and dysregulate intracellular iron in macrophages.
J Immunol Res Volume: 2014 Page(s): 140728
01/01/2014 Authors: Zughaier SM; Stauffer BB; McCarty NA
Ion mobility and liquid chromatography/mass spectrometry strategies for exhaled breath condensate glucose quantitation in cystic fibrosis studies.
Rapid Commun Mass Spectrom Volume: 27 Page(s): 2263 - 2271
10/30/2013 Authors: Monge ME; Prez JJ; Dwivedi P; Zhou M; McCarty NA; Stecenko AA; Fernndez FM
THREE CHARGED AMINO ACIDS IN THE OUTER VESTIBULE OF CFTR STABILIZE THE OPEN PORE ARCHITECTURE
PEDIATRIC PULMONOLOGY Volume: 48 Page(s): 219 - 219
10/01/2013 Authors: Cui G; Kuang C; Rahman KS; Prince CZ; McCarty NA
MISFOLDED CFTR INTERFERES WITH QUALITY CONTROL OF A CONNEXIN-FAMILY GAP JUNCTION PROTEIN
PEDIATRIC PULMONOLOGY Volume: 48 Page(s): 244 - 244
10/01/2013 Authors: Koval M; Molina SA; McCarty NA
MOLECULAR MODELING AND SIMULATIONS OF CHANNEL OPENING IN CFTR
PEDIATRIC PULMONOLOGY Volume: 48 Page(s): 220 - 220
10/01/2013 Authors: Rahman K; Cui G; Harvey SC; McCarty NA
THE STRUCTURAL AND FUNCTIONAL IMPORTANCE OF TYPE II DIVERGENT AMINO ACIDS IN THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
PEDIATRIC PULMONOLOGY Volume: 48 Page(s): 219 - 219
10/01/2013 Authors: Cui G; Wang J; Kuang C; Rahman KS; Prince CZ; Jordan IK; McCarty NA
EXTRACELLULAR PULMONARY REDOX IMBALANCE IN A MURINE MODEL OF CYSTIC FIBROSIS RELATED DIABETES
PEDIATRIC PULMONOLOGY Volume: 48 Page(s): 418 - 419
10/01/2013 Authors: Hunt WR; Zughaier SM; Guentert DE; Koval M; McCarty NA; Hansen JM
HIGH GLUCOSE LEVELS DYSREGULATE NGAL EXPRESSION IN CFTR-DEFICIENT MACROPHAGES
PEDIATRIC PULMONOLOGY Volume: 48 Page(s): 251 - 251
10/01/2013 Authors: Zughaier SM; Guentert DE; Hunt WR; Hansen JM; McCarty NA
Peripheral monocytes derived from patients with cystic fibrosis and healthy donors secrete NGAL in response to Pseudomonas aeruginosa infection.
J Investig Med Volume: 61 Page(s): 1018 - 1025
08/01/2013 Authors: Zughaier SM; Tangpricha V; Leong T; Stecenko AA; McCarty NA
Turning a Transporter into an Open Pore: The CFTR Chloride Channel.
Volume: 142 Page(s): 11A - 12A
08/01/2013 Authors: Mccarty NA
Three Charged Amino Acids in the Outer Vestibule of CFTR Stabilize the Open Pore Architecture
Volume: 142 Page(s): 5A - 6A
08/01/2013 Authors: Cui G; Kuang C; Rahman KS; Prince CZ; Mccarty NA
Two salt bridges differentially contribute to the maintenance of cystic fibrosis transmembrane conductance regulator (CFTR) channel function.
J Biol Chem Volume: 288 Page(s): 20758 - 20767
07/12/2013 Authors: Cui G; Freeman CS; Knotts T; Prince CZ; Kuang C; McCarty NA
Origin and evolution of the cystic fibrosis transmembrane regulator protein R domain.
Gene Volume: 523 Page(s): 137 - 146
07/10/2013 Authors: Sebastian A; Rishishwar L; Wang J; Bernard KF; Conley AB; McCarty NA; Jordan IK
Modeling the conformational changes underlying channel opening in CFTR.
PLoS One Volume: 8 Page(s): e74574
01/01/2013 Authors: Rahman KS; Cui G; Harvey SC; McCarty NA
Formulation of meningococcal capsular polysaccharide vaccine-loaded microparticles with robust innate immune recognition.
J Microencapsul Volume: 30 Page(s): 28 - 41
01/01/2013 Authors: Ubale RV; D'Souza MJ; Infield DT; McCarty NA; Zughaier SM
MODELING THE TRANSLOCATION MECHANISM OF THE ABC TRANSPORTER P-GLYCOPROTEIN USING TARGETED MOLECULAR DYNAMICS
PEDIATRIC PULMONOLOGY Volume: 47 Page(s): 244 - 245
09/01/2012 Authors: Speir E; Rahman K; McCarty NA; Harvey SC
TARGETED MOLECULAR DYNAMICS SIMULATIONS OF THE CFTR GATING CYCLE
PEDIATRIC PULMONOLOGY Volume: 47 Page(s): 244 - 244
09/01/2012 Authors: Rahman K; Cui G; McCarty NA; Harvey SC
ELEVATED AIRWAY AND SYSTEMIC GLUCOSE IMPEDES LUNG BACTERIAL CLEARANCE IN A MURINE MODEL OF CYSTIC FIBROSIS RELATED DIABETES
PEDIATRIC PULMONOLOGY Volume: 47 Page(s): 421 - 421
09/01/2012 Authors: Hunt WR; Zughaier SM; Shenep M; McCarty NA; Hansen JM
EXPRESSION OF DELTA-F508-CFTR LEADS TO DISRUPTION OF THE AIRWAY GLUCOSE BARRIER IN CF-RELATED DIABETES
PEDIATRIC PULMONOLOGY Volume: 47 Page(s): 267 - 267
09/01/2012 Authors: McCarty NA; Hansen JM; Koval MH
ORIGIN AND EVOLUTION OF THE CFTR REGULATORY R-DOMAIN
PEDIATRIC PULMONOLOGY Volume: 47 Page(s): 247 - 247
09/01/2012 Authors: Sebastian A; Rishishwar L; Bernard KF; McCarty NA; Jordan IK
PYOCYANIN MODULATES IRON-LIMITING INNATE IMMUNE DEFENSES IN MACROPHAGES
PEDIATRIC PULMONOLOGY Volume: 47 Page(s): 331 - 331
09/01/2012 Authors: Zughaier SM; Leavey J; McCarty NA
EXTRACELLULAR LOOP 1 IS INVOLVED IN MAINTAINING OUTER VESTIBULE PORE ARCHITECTURE OF CFTR
PEDIATRIC PULMONOLOGY Volume: 47 Page(s): 237 - 238
09/01/2012 Authors: Cui G; Kuang C; Prince CZ; McCarty NA
Differential contribution of TM6 and TM12 to the pore of CFTR identified by three sulfonylurea-based blockers.
Pflugers Arch Volume: 463 Page(s): 405 - 418
03/01/2012 Authors: Cui G; Song B; Turki HW; McCarty NA
Pyoverdine, the Major Siderophore in Pseudomonas aeruginosa, Evades NGAL Recognition.
Interdiscip Perspect Infect Dis Volume: 2012 Page(s): 843509
01/01/2012 Authors: Peek ME; Bhatnagar A; McCarty NA; Zughaier SM
Relating the disease mutation spectrum to the evolution of the cystic fibrosis transmembrane conductance regulator (CFTR).
PLoS One Volume: 7 Page(s): e42336
01/01/2012 Authors: Rishishwar L; Varghese N; Tyagi E; Harvey SC; Jordan IK; McCarty NA
High-sweat Na+ in cystic fibrosis and healthy individuals does not diminish thirst during exercise in the heat.
Am J Physiol Regul Integr Comp Physiol Volume: 301 Page(s): R1177 - R1185
10/01/2011 Authors: Brown MB; McCarty NA; Millard-Stafford M
Low abundance of sweat duct Cl- channel CFTR in both healthy and cystic fibrosis athletes with exceptionally salty sweat during exercise.
Am J Physiol Regul Integr Comp Physiol Volume: 300 Page(s): R605 - R615
03/01/2011 Authors: Brown MB; Haack KKV; Pollack BP; Millard-Stafford M; McCarty NA
Identification of RL-TGR, a coreceptor involved in aversive chemical signaling.
Proc Natl Acad Sci U S A Volume: 107 Page(s): 12339 - 12344
07/06/2010 Authors: Cohen SP; Haack KKV; Halstead-Nussloch GE; Bernard KF; Hatt H; Kubanek J; McCarty NA
A novel bioassay for detecting GPCR heterodimerization: transactivation of beta 2 adrenergic receptor by bradykinin receptor.
J Biomol Screen Volume: 15 Page(s): 251 - 260
03/01/2010 Authors: Haack KKV; Tougas MR; Jones KT; El-Dahr SS; Radhakrishna H; McCarty NA
ELEVATED NGAL LEVELS CONTRIBUTE TO DYSFUNCTIONAL INNATE IMMUNITY IN CYSTIC FIBROSIS
PEDIATRIC PULMONOLOGY Page(s): 274 - 274
01/01/2010 Authors: Zughaier S; Dhakal D; Tangpricha V; McCarty NM
DECREASED VOLUNTARY DRINKING DURING RECOVERY FROM EXERCISE-INDUCED DEHYDRATION FOR CF ATHLETES COMPARED TO HEALTHY ATHLETES: IMPLICATIONS OF HIGH SWEAT SODIUM CHLORIDE CONTENT ON FLUID & ELECTROLYTE BALANCE
PEDIATRIC PULMONOLOGY Page(s): 414 - 415
01/01/2010 Authors: Brown M; Millard-Stafford M; McCarty N
Isolation and characterization of a high affinity peptide inhibitor of ClC-2 chloride channels.
J Biol Chem Volume: 284 Page(s): 26051 - 26062
09/18/2009 Authors: Thompson CH; Olivetti PR; Fuller MD; Freeman CS; McMaster D; French RJ; Pohl J; Kubanek J; McCarty NA
Immunofluorescent localization of cystic fibrosis transmembrane conductance regulator (CFTR) and epithelial sodium channel (ENaC) in human sweat ducts
FASEB JOURNAL Volume: 23
04/01/2009 Authors: Brown MB; Vincent KK; Millard-Stafford M; McCarty NA
Transactivation of Beta 2 Adrenergic Receptor by Bradykinin Receptor via Heterodimerization
FASEB JOURNAL Volume: 23
04/01/2009 Authors: Vincent KK; Tougas M; Jones K; Radhakrishna H; McCarty N
Pharmacological Characterization of GaTx2, a Peptide Inhibitor of ClC-2 Chloride Channels
Volume: 96 Page(s): 470A - 470A
02/01/2009 Authors: Thompson CH; Freeman CS; French RJ; McCarty NA
Evolutionary and functional divergence between the cystic fibrosis transmembrane conductance regulator and related ATP-binding cassette transporters.
Proc Natl Acad Sci U S A Volume: 105 Page(s): 18865 - 18870
12/02/2008 Authors: Jordan IK; Kota KC; Cui G; Thompson CH; McCarty NA
Isolation of a Candidate Receptor that Responds to a Chemical Defense Compound
Volume: 33 Page(s): S58 - S58
10/01/2008 Authors: Cohen SP; Halstead-Nussloch GE; Kubanek J; McCarty NA
Mutations at arginine 352 alter the pore architecture of CFTR.
J Membr Biol Volume: 222 Page(s): 91 - 106
03/01/2008 Authors: Cui G; Zhang Z-R; O'Brien ARW; Song B; McCarty NA
Reconstitution of a chemical defense signaling pathway in a heterologous system.
J Exp Biol Volume: 211 Page(s): 599 - 605
02/01/2008 Authors: Cohen SAP; Hatt H; Kubanek J; McCarty NA
State-dependent inhibition of cystic fibrosis transmembrane conductance regulator chloride channels by a novel peptide toxin.
J Biol Chem Volume: 282 Page(s): 37545 - 37555
12/28/2007 Authors: Fuller MD; Thompson CH; Zhang Z-R; Freeman CS; Schay E; Szakcs G; Bakos E; Sarkadi B; McMaster D; French RJ
GaTx1: A novel peptide toxin inhibitor of CFTR
Page(s): 275A - 275A
01/01/2007 Authors: Fuller MD; Thompson C; Pohl J; Kubanek J; McCarty NA
GaTx2: A high affinity peptide toxin inhibitor of CLC-2 chloride channels
PEDIATRIC PULMONOLOGY Page(s): 242 - 242
01/01/2007 Authors: McCarty NA; Thompson CH
GaTx2: A novel peptide inhibitor of CIC-2
Page(s): 272A - 272A
01/01/2007 Authors: Thompson CH; Fuller MD; Pohl J; Kubanek J; McCarty NA
Reconstitution of a chemical defense signaling pathway in a heterologous system
Volume: 31 Page(s): A84 - A84
06/01/2006 Authors: Padove SA; Kubanek J; Hatt H; McCarty NA
State-dependent chemical reactivity of an engineered cysteine reveals conformational changes in the outer vestibule of the cystic fibrosis transmembrane conductance regulator.
J Biol Chem Volume: 280 Page(s): 41997 - 42003
12/23/2005 Authors: Zhang Z-R; Song B; McCarty NA
The block of CFTR by scorpion venom is state-dependent.
Biophys J Volume: 89 Page(s): 3960 - 3975
12/01/2005 Authors: Fuller MD; Zhang Z-R; Cui G; McCarty NA
Inhibition of ClC-2 chloride channels by a peptide component or components of scorpion venom.
J Membr Biol Volume: 208 Page(s): 65 - 76
11/01/2005 Authors: Thompson CH; Fields DM; Olivetti PR; Fuller MD; Zhang ZR; Kubanek J; McCarty NA
Determination of the functional unit of the cystic fibrosis transmembrane conductance regulator chloride channel. One polypeptide forms one pore.
J Biol Chem Volume: 280 Page(s): 458 - 468
01/07/2005 Authors: Zhang Z-R; Cui G; Liu X; Song B; Dawson DC; McCarty NA
Mutations at arginine 352 alter the pore architecture of CFTR
Volume: 88 Page(s): 612A - 612A
01/01/2005 Authors: Cui GY; Song BL; McCarty NA
The block of CFTR by scorpion venom is state dependent
Volume: 88 Page(s): 611A - 611A
01/01/2005 Authors: Fuller MD; Zhang ZR; Cui GY; McCarty NA
CFTR: a cysteine at position 338 in TM6 senses a positive electrostatic potential in the pore.
Biophys J Volume: 87 Page(s): 3826 - 3841
12/01/2004 Authors: Liu X; Zhang Z-R; Fuller MD; Billingsley J; McCarty NA; Dawson DC
Inhibition of CFTR channels by a peptide toxin of scorpion venom.
Am J Physiol Cell Physiol Volume: 287 Page(s): C1328 - C1341
11/01/2004 Authors: Fuller MD; Zhang Z-R; Cui G; Kubanek J; McCarty NA
Time-dependent interactions of glibenclamide with CFTR: kinetically complex block of macroscopic currents.
J Membr Biol Volume: 201 Page(s): 139 - 155
10/01/2004 Authors: Zhang Z-R; Cui G; Zeltwanger S; McCarty NA
The functional unit for CFTR Cl- channels: One polypeptide = one pore
Volume: 124 Page(s): 26A - 26A
07/01/2004 Authors: Zhang ZR; Liu XH; Dawson DC; Mccarty NA
Steady-state interactions of glibenclamide with CFTR: evidence for multiple sites in the pore.
J Membr Biol Volume: 199 Page(s): 15 - 28
05/01/2004 Authors: Zhang ZR; Zeltwanger S; McCarty NA
CFTR: One pore channel
Volume: 86 Page(s): 586A - 586A
01/01/2004 Authors: Zhang ZR; Cui GY; Song BL; Liu XH; Dawson DC; McCarty NA
Differential block of CFTR pore by three members of the sulphonylurea family
Volume: 86 Page(s): 586A - 586A
01/01/2004 Authors: Cui GY; Song BL; McCarty NA
Inhibition of ClC-2 by a peptide component of scorpion venom
Volume: 86 Page(s): 586A - 586A
01/01/2004 Authors: Thompson CI; Fields D; Zhang ZR; McCarty NA
Inhibition of ClC-2 by a component of scorpion venom
Volume: 122 Page(s): 29A - 30A
07/01/2003 Authors: Thompson CH; Fields DM; Hubbard K; Zhang ZR; Mccarty NA
Inhibition of CFTR channels by a peptide toxin of scorpion venom
Volume: 122 Page(s): 23A - 23A
07/01/2003 Authors: Fuller MD; Zhang ZR; Cui GY; Mccarty NA
Transient transfection of polarized epithelial monolayers with CFTR and reporter genes using efficacious lipids.
Am J Physiol Cell Physiol Volume: 284 Page(s): C791 - C804
03/01/2003 Authors: Tucker TA; Varga K; Bebok Z; Zsembery A; McCarty NA; Collawn JF; Schwiebert EM; Schwiebert LM
CFTR channel inhibition by a peptide toxin of scorpion venom
Volume: 84 Page(s): 82A - 83A
02/01/2003 Authors: Fuller MD; Zhang ZR; Cui GY; McCarty NA
Probing a new mechanism of glibenclamide interation with CFTR: gating efffects
Volume: 84 Page(s): 83A - 83A
02/01/2003 Authors: Cui GY; McCarty NA
Use of nasal potential differences and sweat chloride as outcome measures in multicenter clinical trials in subjects with cystic fibrosis - Reply
PEDIATRIC PULMONOLOGY Volume: 34 Page(s): 156 - 156
08/01/2002 Authors: Ahrens RC; Aitken ML; Konstan MW; McCarty NA
Response to "Use of nasal potential differences and sweat chloride as outcome measures in multicenter clinical trials in subjects with cystic fibrosis".
Pediatr Pulmonol Volume: 34 Page(s): 155
08/01/2002 Authors: LeGrys VA
A phase I randomized, multicenter trial of CPX in adult subjects with mild cystic fibrosis.
Pediatr Pulmonol Volume: 33 Page(s): 90 - 98
02/01/2002 Authors: McCarty NA; Standaert TA; Teresi M; Tuthill C; Launspach J; Kelley TJ; Milgram LJH; Hilliard KA; Regelmann WE; Weatherly MR
Use of nasal potential difference and sweat chloride as outcome measures in multicenter clinical trials in subjects with cystic fibrosis.
Pediatr Pulmonol Volume: 33 Page(s): 142 - 150
02/01/2002 Authors: Ahrens RC; Standaert TA; Launspach J; Han S-H; Teresi ME; Aitken ML; Kelley TJ; Hilliard KA; Milgram LJH; Konstan MW
Voltage-sensitive gating induced by a mutation in the fifth transmembrane domain of CFTR.
Am J Physiol Lung Cell Mol Physiol Volume: 282 Page(s): L135 - L145
01/01/2002 Authors: Zhang Z-R; Zeltwanger S; Smith SS; Dawson DC; McCarty NA
CFTR: covalent and noncovalent modification suggests a role for fixed charges in anion conduction.
J Gen Physiol Volume: 118 Page(s): 407 - 431
10/01/2001 Authors: Smith SS; Liu X; Zhang ZR; Sun F; Kriewall TE; McCarty NA; Dawson DC
Identification of a region of strong discrimination in the pore of CFTR.
Am J Physiol Lung Cell Mol Physiol Volume: 281 Page(s): L852 - L867
10/01/2001 Authors: McCarty NA; Zhang ZR
Identification of a region of high discrimination in the pore of the CFTR channel.
BIOPHYSICAL JOURNAL Volume: 80 Page(s): 470A - 470A
01/01/2001 Authors: Zhang ZR; McCarty NA
Interaction between permeation and gating in a putative pore domain mutant in the cystic fibrosis transmembrane conductance regulator.
Biophys J Volume: 79 Page(s): 298 - 313
07/01/2000 Authors: Zhang ZR; McDonough SI; McCarty NA
Permeation through the CFTR chloride channel.
J Exp Biol Volume: 203 Page(s): 1947 - 1962
07/01/2000 Authors: McCarty NA
Direct comparison of NPPB and DPC as probes of CFTR expressed in Xenopus oocytes.
J Membr Biol Volume: 175 Page(s): 35 - 52
05/01/2000 Authors: Zhang ZR; Zeltwanger S; McCarty NA
CFTR: A mutation in TM5 (V317E) results in voltage-dependent open probability
BIOPHYSICAL JOURNAL Volume: 78 Page(s): 467A - 467A
01/01/2000 Authors: Zeltwanger S; Zhang ZR; Smith SS; Dawson DC; McCarty NA
Glibenclamide inhibits CFTR activity through interaction with multiple sites with varying affinities and pH-dependencies
BIOPHYSICAL JOURNAL Volume: 78 Page(s): 467A - 467A
01/01/2000 Authors: Zeltwanger S; Zhang ZR; McCarty NA
Building a 3-dimensional model of permeation in the CFTR Cl channel.
FASEB JOURNAL Volume: 13 Page(s): A70 - A70
03/12/1999 Authors: McCarty NA; Zhang ZR
Direct identification of the putative receptor for the fast inactivation gate in shaker K channels
BIOPHYSICAL JOURNAL Volume: 76 Page(s): A192 - A192
01/01/1999 Authors: Vogler B; Riley CP; Nahm GH; Buck CR; McCarty NA
Interaction between permeation and gating studied in a pore-domain mutant in CFTR
BIOPHYSICAL JOURNAL Volume: 74 Page(s): A396 - A396
02/01/1998 Authors: McCarty NA; Zhang ZR
Voltage-jump relaxations in a CFTR mutant
BIOPHYSICAL JOURNAL Volume: 74 Page(s): A395 - A395
02/01/1998 Authors: McDonough S; Zhang ZR; Davidson N; Lester HA; McCarty NA
Relationship between airway ion transport and a mild pulmonary disease mutation in CFTR.
Am J Respir Crit Care Med Volume: 155 Page(s): 1684 - 1689
05/01/1997 Authors: Walker LC; Venglarik CJ; Aubin G; Weatherly MR; McCarty NA; Lesnick B; Ruiz F; Clancy JP; Sorscher EJ
Novel pore-lining residues in CFTR that govern permeation and open-channel block.
Neuron Volume: 13 Page(s): 623 - 634
09/01/1994 Authors: McDonough S; Davidson N; Lester HA; McCarty NA
Voltage-dependent block of the cystic fibrosis transmembrane conductance regulator Cl- channel by two closely related arylaminobenzoates.
J Gen Physiol Volume: 102 Page(s): 1 - 23
07/01/1993 Authors: McCarty NA; McDonough S; Cohen BN; Riordan JR; Davidson N; Lester HA
Receptors that couple to 2 classes of G proteins increase cAMP and activate CFTR expressed in Xenopus oocytes.
Recept Channels Volume: 1 Page(s): 233 - 241
01/01/1993 Authors: Uezono Y; Bradley J; Min C; McCarty NA; Quick M; Riordan JR; Chavkin C; Zinn K; Lester HA; Davidson N
Effects of serotonin on intracellular pH and contraction in vascular smooth muscle.
Circ Res Volume: 71 Page(s): 1294 - 1304
12/01/1992 Authors: Kahn AM; Bishara M; Cragoe EJ; Allen JC; Seidel CL; Navran SS; O'Neil RG; McCarty NA; Shelat H
Calcium signaling in cell volume regulation.
Physiol Rev Volume: 72 Page(s): 1037 - 1061
10/01/1992 Authors: McCarty NA; O'Neil RG
Calcium-dependent control of volume regulation in renal proximal tubule cells: II. Roles of dihydropyridine-sensitive and -insensitive Ca2+ entry pathways.
J Membr Biol Volume: 123 Page(s): 161 - 170
08/01/1991 Authors: McCarty NA; O'Neil RG
Calcium-dependent control of volume regulation in renal proximal tubule cells: I. Swelling-activated Ca2+ entry and release.
J Membr Biol Volume: 123 Page(s): 149 - 160
08/01/1991 Authors: McCarty NA; O'Neil RG
Dihydropyridine-sensitive cell volume regulation in proximal tubule: the calcium window.
Am J Physiol Volume: 259 Page(s): F950 - F960
12/01/1990 Authors: McCarty NA; O'Neil RG
DIHYDROPYRIDINE-SENSITIVE CELL-VOLUME REGULATION IN PROXIMAL TUBULE - THE CALCIUM WINDOW
AMERICAN JOURNAL OF PHYSIOLOGY Volume: 259 Page(s): F950 - F960
12/01/1990 Authors: MCCARTY NA; ONEIL RG
CALCIUM DEPENDENCY OF HYPOTONIC VOLUME REGULATION IN PROXIMAL TUBULE
KIDNEY INTERNATIONAL Volume: 33 Page(s): 436 - 436
01/01/1988 Authors: MCCARTY NA; REID JM; ONEIL RG

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Nael McCarty PhD

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