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Profile

Mehul Suthar

  • Department of Pediatrics
    Associate Professor
  • (404) 727-3052
  • mehul.s.suthar@emory.edu
Head shot of Mehul Suthar

Academic Appointment

  • Adjunct Faculty, Microbiology and Immunology, Emory University
  • Assistant Professor, Department of Pediatrics, Emory University
  • Emory Vaccine Center Member, Emory University

Education

Degrees

  • PhD from University of North Carolina-Chapel Hill
  • BS from Pennsylvania State University, University Park

Research

Publications

  • Altered baseline immunological state and impaired immune response to SARS-CoV-2 mRNA vaccination in lung transplant recipients.
    Cell Rep Med Volume: 6 Page(s): 102050
    04/15/2025 Authors: Hu M; Oliveira APBN; Fang Z; Feng Y; Miranda M; Kowli S; Arunachalam PS; Vasudevan G; Hui HS-Y; Grifoni A
  • SARS-CoV-2: The Interplay Between Evolution and Host Immunity.
    Annu Rev Immunol Volume: 43 Page(s): 29 - 55
    04/01/2025 Authors: Case JB; Jain S; Suthar MS; Diamond MS
  • The furin cleavage site is required for pathogenesis, but not transmission of SARS-CoV-2.
    bioRxiv
    03/11/2025 Authors: Morgan AL; Vu MN; Zhou Y; Lokugamage KG; Meyers WM; Alvarado RE; Ahearn Y; Estes LK; Plante JA; Johnson BA
  • The KP.2-adapted COVID-19 vaccine improves neutralising activity against the XEC variant.
    Lancet Infect Dis Volume: 25 Page(s): e122 - e123
    03/01/2025 Authors: Suthar MS; Manning KE; Ellis ML; Jain S; Bechnak K; Vander Velden J; Laboune F; Henry AR; Godbole S; Kim S
  • Longitudinal Surveillance of COVID-19 Antibodies in Pediatric Healthcare Workers.
    Vaccines (Basel) Volume: 13
    02/07/2025 Authors: Hatabah D; Gupta SL; Mantus G; Sullivan P; Heilman S; Camacho-Gonzalez A; Leake D; Le M; Griffiths M; Norwood C
  • A Phase 1 randomized trial of homologous and heterologous filovirus vaccines with a late booster dose.
    NPJ Vaccines Volume: 9 Page(s): 255
    12/23/2024 Authors: Rostad CA; Yildirim I; Kao C; Yi J; Kamidani S; Peters E; Stephens K; Gibson T; Hsiao H-M; Singh K
  • A Global Collaborative Comparison of SARS-CoV-2 Antigenicity Across 15 Laboratories.
    Viruses Volume: 16
    12/18/2024 Authors: Brangel P; Tureli S; Mhlemann B; Liechti N; Zysset D; Engler O; Hunger-Glaser I; Ghiga I; Mattiuzzo G; Eckerle I
  • Tissue-resident memory T cells contribute to protection against heterologous SARS-CoV-2 challenge.
    JCI Insight Volume: 9
    12/06/2024 Authors: Odle A; Kar M; Verma AK; Sariol A; Meyerholz DK; Suthar MS; Wong L-YR; Perlman S
  • Corrigendum to "Incidence of SARS-CoV-2 seropositivity in pediatric healthcare workers prior to widespread vaccination: A 5-month longitudinal cohort study" [Internation Journal of Infectious Diseases, volume 144 (2024) 107064].
    Int J Infect Dis Volume: 149 Page(s): 107278
    12/01/2024 Authors: Griffiths M; Hatabah D; Sullivan P; Mantus G; Sanchez T; Zlotorzynska M; Heilman S; Camacho-Gonzalez A; Leake D; Korman R
  • Enhanced D614G and Omicron Variants Antibody Persistence in Infants at 2 Months of Age Following Maternal mRNA Booster Vaccination During Pregnancy or Postpartum.
    Pediatr Infect Dis J Volume: 43 Page(s): 1065 - 1073
    11/01/2024 Authors: Munoz FM; Beigi R; Posavad CM; Kelly C; Badell ML; Bunge K; Mulligan MJ; Parameswaran L; Richardson BA; Olsen-Chen C
  • Divergence of variant antibodies following SARS-CoV-2 booster vaccines in myeloma and impact of hybrid immunity.
    NPJ Vaccines Volume: 9 Page(s): 201
    10/27/2024 Authors: Moreno A; Manning K; Azeem MI; Nooka AK; Ellis M; Manalo RJ; Switchenko JM; Wali B; Kaufman JL; Hofmeister CC
  • Immunogenicity and efficacy of XBB.1.5 rS vaccine against the EG.5.1 variant of SARS-CoV-2 in Syrian hamsters.
    J Virol Volume: 98 Page(s): e0052824
    10/22/2024 Authors: Soudani N; Bricker TL; Darling T; Seehra K; Patel N; Guebre-Xabier M; Smith G; Davis-Gardner M; Suthar MS; Ellebedy AH
  • A multispecific antibody against SARS-CoV-2 prevents immune escape in vitro and confers prophylactic protection in vivo.
    Sci Transl Med Volume: 16 Page(s): eado9026
    10/09/2024 Authors: Misasi J; Wei RR; Wang L; Pegu A; Wei C-J; Oloniniyi OK; Zhou T; Moliva JI; Zhao B; Choe M
  • Mucosal adenovirus vaccine boosting elicits IgA and durably prevents XBB.1.16 infection in nonhuman primates.
    Nat Immunol Volume: 25 Page(s): 1913 - 1927
    10/01/2024 Authors: Gagne M; Flynn BJ; Andrew SF; Marquez J; Flebbe DR; Mychalowych A; Lamb E; Davis-Gardner ME; Burnett MR; Serebryannyy LA
  • Efficacy of late-onset antiviral treatment in immunocompromised hosts with persistent SARS-CoV-2 infection.
    J Virol Volume: 98 Page(s): e0090524
    09/17/2024 Authors: Lieber CM; Kang H-J; Sobolik EB; Sticher ZM; Ngo VL; Gewirtz AT; Kolykhalov AA; Natchus MG; Greninger AL; Suthar MS
  • CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment.
    Sci Adv Volume: 10 Page(s): eadp2636
    08/23/2024 Authors: Kar M; Johnson KEE; Vanderheiden A; Elrod EJ; Floyd K; Geerling E; Stone ET; Salinas E; Banakis S; Wang W
  • Variant-proof high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways.
    Nat Commun Volume: 15 Page(s): 6894
    08/12/2024 Authors: Gagne M; Flynn BJ; Honeycutt CC; Flebbe DR; Andrew SF; Provost SJ; McCormick L; Van Ry A; McCarthy E; Todd J-PM
  • Eosinophils protect against SARS-CoV-2 following a vaccine breakthrough infection.
    bioRxiv
    08/10/2024 Authors: Moore KM; Foster SL; Kar M; Floyd KA; Elrod EJ; Williams ME; Velden JV; Ellis M; Malik A; Wali B
  • Patients taking benralizumab, dupilumab, or mepolizumab have lower postvaccination SARS-CoV-2 immunity.
    J Allergy Clin Immunol Volume: 154 Page(s): 435 - 446
    08/01/2024 Authors: Runnstrom MC; Lamothe PA; Faliti CE; Cheedarla N; Moreno A; Suthar MS; Nahata R; Ravindran M; Haddad NS; Morrison-Porter A
  • Incidence of SARS-CoV-2 seropositivity in pediatric healthcare workers prior to widespread vaccination: A 5-month longitudinal cohort study.
    Int J Infect Dis Volume: 144 Page(s): 107064
    07/01/2024 Authors: Griffiths M; Hatabah D; Sullivan P; Mantus G; Sanchez T; Zlotorzynska M; Heilman S; Camacho-Gonzalez A; Leake D; Korman R
  • Efficacy of late-onset antiviral treatment in immune-compromised hosts with persistent SARS-CoV-2 infection.
    bioRxiv
    05/23/2024 Authors: Lieber CM; Kang H-J; Sobolik EB; Sticher ZM; Ngo VL; Gewirtz AT; Kolykhalov AA; Natchus MG; Greninger AL; Suthar MS
  • Comparative analysis of SARS-CoV-2 neutralization titers reveals consistency between human and animal model serum and across assays.
    Sci Transl Med Volume: 16 Page(s): eadl1722
    05/15/2024 Authors: Mhlemann B; Wilks SH; Baracco L; Bekliz M; Carreo JM; Corman VM; Davis-Gardner ME; Dejnirattisai W; Diamond MS; Douek DC
  • Single-cell analysis reveals an antiviral network that controls Zika virus infection in human dendritic cells.
    J Virol Volume: 98 Page(s): e0019424
    05/14/2024 Authors: Moore KM; Pelletier A-N; Lapp S; Metz A; Tharp GK; Lee M; Bhasin SS; Bhasin M; Skaly R-P; Bosinger SE
  • Durability of immune responses to SARS-CoV-2 infection and vaccination.
    Semin Immunol Volume: 73 Page(s): 101884
    05/01/2024 Authors: Suthar MS
  • SARS-CoV-2 Viral Shedding and Rapid Antigen Test Performance - Respiratory Virus Transmission Network, November 2022-May 2023.
    MMWR Morb Mortal Wkly Rep Volume: 73 Page(s): 365 - 371
    04/25/2024 Authors: Smith-Jeffcoat SE; Mellis AM; Grijalva CG; Talbot HK; Schmitz J; Lutrick K; Ellingson KD; Stockwell MS; McLaren SH; Nguyen HQ
  • AS03 adjuvant enhances the magnitude, persistence, and clonal breadth of memory B cell responses to a plant-based COVID-19 vaccine in humans.
    Sci Immunol Volume: 9 Page(s): eadi8039
    04/05/2024 Authors: Grigoryan L; Feng Y; Bellusci L; Lai L; Wali B; Ellis M; Yuan M; Arunachalam PS; Hu M; Kowli S
  • Maternal COVID-19 Vaccination and Prevention of Symptomatic Infection in Infants.
    Pediatrics Volume: 153
    03/01/2024 Authors: Cardemil CV; Cao Y; Posavad CM; Badell ML; Bunge K; Mulligan MJ; Parameswaran L; Olson-Chen C; Novak RM; Brady RC
  • Immunogenicity and efficacy of XBB.1.5 rS vaccine against EG.5.1 variant of SARS-CoV-2 in Syrian hamsters.
    Res Sq
    02/09/2024 Authors: Boon J; Soudani N; Bricker T; Darling T; Seehra K; Patel N; Guebre-Xabier M; Smith G; Suthar M; Ellebedy A
  • XBB.1.5 monovalent booster improves antibody binding and neutralization against emerging SARS-CoV-2 Omicron variants.
    bioRxiv
    02/05/2024 Authors: Jain S; Kumar S; Lai L; Linderman S; Malik AA; Ellis ML; Godbole S; Solis D; Sahoo MK; Bechnak K
  • Mucosal boosting enhances vaccine protection against SARS-CoV-2 in macaques.
    Nature Volume: 626 Page(s): 385 - 391
    02/01/2024 Authors: McMahan K; Wegmann F; Aid M; Sciacca M; Liu J; Hachmann NP; Miller J; Jacob-Dolan C; Powers O; Hope D
  • CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment.
    bioRxiv
    01/24/2024 Authors: Kar M; Johnson KEE; Vanderheiden A; Elrod EJ; Floyd K; Geerling E; Stone ET; Salinas E; Banakis S; Wang W
  • Single cell analysis reveals an antiviral network that controls Zika virus infection in human dendritic cells.

    01/21/2024 Authors: Moore KM; Pelletier A-N; Lapp S; Metz A; Tharp GK; Lee M; Bhasin SS; Bhasin M; Skaly R-P; Bosinger SE
  • BCG vaccination stimulates integrated organ immunity by feedback of the adaptive immune response to imprint prolonged innate antiviral resistance.
    Nat Immunol Volume: 25 Page(s): 41 - 53
    01/01/2024 Authors: Lee A; Floyd K; Wu S; Fang Z; Tan TK; Froggatt HM; Powers JM; Leist SR; Gully KL; Hubbard ML
  • Durable immunity to SARS-CoV-2 in both lower and upper airways achieved with a gorilla adenovirus (GRAd) S-2P vaccine in non-human primates.
    bioRxiv
    11/22/2023 Authors: Moliva JI; Andrew SF; Flynn BJ; Wagner DA; Foulds KE; Gagne M; Flebbe DR; Lamb E; Provost S; Marquez J
  • BA.5 bivalent booster vaccination enhances neutralization of XBB.1.5, XBB.1.16 and XBB.1.9 variants in patients with lung cancer.
    NPJ Vaccines Volume: 8 Page(s): 179
    11/21/2023 Authors: Valanparambil RM; Lai L; Johns MA; Davis-Gardner M; Linderman SL; McPherson TO; Chang A; Akhtar A; Gamarra ELB; Matia H
  • Mucosal Adenoviral-vectored Vaccine Boosting Durably Prevents XBB.1.16 Infection in Nonhuman Primates.
    bioRxiv
    11/08/2023 Authors: Gagne M; Flynn BJ; Andrew SF; Flebbe DR; Mychalowych A; Lamb E; Davis-Gardner ME; Burnett MR; Serebryannyy LA; Lin BC
  • Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS-CoV-2 infection and COVID-19 disease severity.
    FASEB J Volume: 37 Page(s): e23220
    11/01/2023 Authors: Tedbury PR; Manfredi C; Degenhardt F; Conway J; Horwath MC; McCracken C; Sorscher AJ; Moreau S; Wright C; Edwards C
  • Efficacy of mRNA-1273 and Novavax ancestral or BA.1 spike booster vaccines against SARS-CoV-2 BA.5 infection in nonhuman primates.
    Sci Immunol Volume: 8 Page(s): eadg7015
    10/27/2023 Authors: Routhu NK; Stampfer SD; Lai L; Akhtar A; Tong X; Yuan D; Chicz TM; McNamara RP; Jakkala K; Davis-Gardner ME
  • Infants and young children generate more durable antibody responses to SARS-CoV-2 infection than adults.
    iScience Volume: 26 Page(s): 107967
    10/20/2023 Authors: Joshi D; Nyhoff LE; Zarnitsyna VI; Moreno A; Manning K; Linderman S; Burrell AR; Stephens K; Norwood C; Mantus G
  • Preclinical development of modified vaccinia virus Ankara vaccines against SARS-CoV-2 infections
    Volume: 52 Page(s): 304 - 304
    10/01/2023 Authors: Routhu NK; Gangadhara S; Lai L; Davis-Gardner ME; Floyd K; Shiferaw A; Bartsch YC; Fischinger S; Khoury G; Rahman SA
  • Comparative Analysis of SARS-CoV-2 Antigenicity across Assays and in Human and Animal Model Sera.
    bioRxiv
    09/27/2023 Authors: Mhlemann B; Wilks SH; Baracco L; Bekliz M; Carreo JM; Corman VM; Davis-Gardner ME; Dejnirattisai W; Diamond MS; Douek DC
  • Light chain of a public SARS-CoV-2 class-3 antibody modulates neutralization against Omicron.
    Cell Rep Volume: 42 Page(s): 113150
    09/26/2023 Authors: Patel A; Kumar S; Lai L; Keen M; Valanparambil R; Chakravarthy C; Laughlin Z; Frank F; Cheedarla N; Verkerke HP
  • Divergence of variant binding/neutralizing antibodies following SARS-CoV-2 booster vaccines in myeloma: Impact of hybrid immunity.
    Res Sq
    09/21/2023 Authors: Moreno A; Manning K; Azeem MI; Nooka AK; Ellis M; Manalo RJ; Switchenko JM; Wali B; Kaufman JL; Hofmeister CC
  • IFN- derived from nonsusceptible enterocytes acts on tuft cells to limit persistent norovirus.
    Sci Adv Volume: 9 Page(s): eadi2562
    09/15/2023 Authors: Ingle H; Makimaa H; Aggarwal S; Deng H; Foster L; Li Y; Kennedy EA; Peterson ST; Wilen CB; Lee S
  • A wild boar cathelicidin peptide derivative inhibits severe acute respiratory syndrome coronavirus-2 and its drifted variants.
    Sci Rep Volume: 13 Page(s): 14650
    09/05/2023 Authors: von Beck T; Navarrete K; Arce NA; Gao M; Dale GA; Davis-Gardner ME; Floyd K; Mena Hernandez L; Mullick N; Vanderheiden A
  • Atovaquone and Pibrentasvir Inhibit the SARS-CoV-2 Endoribonuclease and Restrict Infection In Vitro but Not In Vivo.
    Viruses Volume: 15
    08/30/2023 Authors: von Beck T; Mena Hernandez L; Zhou H; Floyd K; Suthar MS; Skolnick J; Jacob J
  • Divergence of variant binding/neutralizing antibodies following SARS-CoV-2 booster vaccines in myeloma: Impact of hybrid immunity.
    bioRxiv
    08/22/2023 Authors: Moreno A; Manning K; Azeem MI; Nooka AK; Ellis M; Manalo RJ; Switchenko JM; Wali B; Kaufman JL; Hofmeister CC
  • Treatment with sofosbuvir attenuates the adverse neurodevelopmental consequences of Zika virus infection in infant rhesus macaques.
    J Neuroimmunol Volume: 381 Page(s): 578148
    08/15/2023 Authors: Medina A; Rusnak R; Richardson R; Zimmerman MG; Suthar M; Schoof N; Kovacs-Balint Z; Mavigner M; Sanchez M; Chahroudi A
  • COVID-19 booster vaccination during pregnancy enhances maternal binding and neutralizing antibody responses and transplacental antibody transfer to the newborn.
    Vaccine Volume: 41 Page(s): 5296 - 5303
    08/14/2023 Authors: Munoz FM; Posavad CM; Richardson BA; Badell ML; Bunge KE; Mulligan MJ; Parameswaran L; Kelly CW; Olson-Chen C; Novak RM
  • Immunogenicity of NVX-CoV2373 heterologous boost against SARS-CoV-2 variants.
    NPJ Vaccines Volume: 8 Page(s): 98
    07/11/2023 Authors: Lyke KE; Atmar RL; Dominguez Islas C; Posavad CM; Deming ME; Branche AR; Johnston C; El Sahly HM; Edupuganti S; Mulligan MJ
  • Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
    Structure Volume: 31 Page(s): 801 - 811.e5
    07/06/2023 Authors: Patel A; Kumar S; Lai L; Chakravarthy C; Valanparambil R; Reddy ES; Gottimukkala K; Bajpai P; Raju DR; Edara VV
  • Low neutralizing activity of AZD7442 against current SARS-CoV-2 Omicron variants in patients with B-cell malignancies.
    Blood Adv Volume: 7 Page(s): 2459 - 2462
    06/13/2023 Authors: Chang A; Koff JL; Lai L; Orellana-Noia VM; Surati M; Leal AMK; Ellis ML; Wali B; Moreno A; Linderman SL
  • Addendum: Systems vaccinology of the BNT162b2 mRNA vaccine in humans.
    Nature Volume: 618 Page(s): E18
    06/01/2023 Authors: Arunachalam PS; Scott MKD; Hagan T; Li C; Feng Y; Wimmers F; Grigoryan L; Trisal M; Edara VV; Lai L
  • Durability of immune responses to mRNA booster vaccination against COVID-19.
    J Clin Invest Volume: 133
    05/15/2023 Authors: Arunachalam PS; Lai L; Samaha H; Feng Y; Hu M; Hui HS-Y; Wali B; Ellis M; Davis-Gardner ME; Huerta C
  • Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.
    Sci Transl Med Volume: 15 Page(s): eadg7404
    05/10/2023 Authors: Feng Y; Yuan M; Powers JM; Hu M; Munt JE; Arunachalam PS; Leist SR; Bellusci L; Kim J; Sprouse KR
  • Virology under the Microscope-a Call for Rational Discourse.
    mSphere Volume: 8 Page(s): e0003423
    04/20/2023 Authors: Goodrum F; Lowen AC; Lakdawala S; Alwine J; Casadevall A; Imperiale MJ; Atwood W; Avgousti D; Baines J; Banfield B
  • Ad26.COV2.S and SARS-CoV-2 spike protein ferritin nanoparticle vaccine protect against SARS-CoV-2 Omicron BA.5 challenge in macaques.
    Cell Rep Med Volume: 4 Page(s): 101018
    04/18/2023 Authors: Yu J; Thomas PV; Sciacca M; Wu C; Liu J; He X; Miller J; Hachmann NP; Surve N; McMahan K
  • Infants and young children generate more durable antibody responses to SARS-CoV-2 infection than adults.
    medRxiv
    04/11/2023 Authors: Joshi D; Nyhoff LE; Zarnitsyna VI; Moreno A; Manning K; Linderman S; Burrell AR; Stephens K; Norwood C; Mantus G
  • Interferon-induced transmembrane protein 3 (IFITM3) limits lethality of SARS-CoV-2 in mice.
    EMBO Rep Volume: 24 Page(s): e56660
    04/05/2023 Authors: Kenney AD; Zani A; Kawahara J; Eddy AC; Wang X-L; Mahesh KC; Lu M; Thomas J; Kohlmeier JE; Suthar MS
  • Impaired SARS-CoV-2 Variant Neutralization and CD8+ T-cell Responses Following 3 Doses of mRNA Vaccines in Myeloma: Correlation with Breakthrough Infections.
    Blood Cancer Discov Volume: 4 Page(s): 106 - 117
    03/01/2023 Authors: Azeem MI; Nooka AK; Shanmugasundaram U; Cheedarla N; Potdar S; Manalo RJ; Moreno A; Switchenko JM; Cheedarla S; Doxie DB
  • Virology under the Microscope-a Call for Rational Discourse.
    J Virol Volume: 97 Page(s): e0008923
    02/28/2023 Authors: Goodrum F; Lowen AC; Lakdawala S; Alwine J; Casadevall A; Imperiale MJ; Atwood W; Avgousti D; Baines J; Banfield B
  • Virology under the Microscope-a Call for Rational Discourse.
    mBio Volume: 14 Page(s): e0018823
    02/28/2023 Authors: Goodrum F; Lowen AC; Lakdawala S; Alwine J; Casadevall A; Imperiale MJ; Atwood W; Avgousti D; Baines J; Banfield B
  • An inactivated NDV-HXP-S COVID-19 vaccine elicits a higher proportion of neutralizing antibodies in humans than mRNA vaccination.
    Sci Transl Med Volume: 15 Page(s): eabo2847
    02/15/2023 Authors: Carreo JM; Raskin A; Singh G; Tcheou J; Kawabata H; Gleason C; Srivastava K; Vigdorovich V; Dambrauskas N; Gupta SL
  • Ablation of Adar1 in myeloid cells imprints a global antiviral state in the lung and heightens early immunity against SARS-CoV-2.
    Cell Rep Volume: 42 Page(s): 112038
    01/31/2023 Authors: Adamska JZ; Verma R; Gupta S; Hagan T; Wimmers F; Floyd K; Li Q; Valore EV; Wang Y; Trisal M
  • Neutralization against BA.2.75.2, BQ.1.1, and XBB from mRNA Bivalent Booster.
    N Engl J Med Volume: 388 Page(s): 183 - 185
    01/12/2023 Authors: Davis-Gardner ME; Lai L; Wali B; Samaha H; Solis D; Lee M; Porter-Morrison A; Hentenaar IT; Yamamoto F; Godbole S
  • Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design.
    PLoS One Volume: 18 Page(s): e0286297
    01/01/2023 Authors: Horwitz LI; Thaweethai T; Brosnahan SB; Cicek MS; Fitzgerald ML; Goldman JD; Hess R; Hodder SL; Jacoby VL; Jordan MR
  • Durability of immune responses to the booster mRNA vaccination against COVID-19.
    medRxiv
    12/04/2022 Authors: Arunachalam PS; Lai L; Samaha H; Feng Y; Hu M; Hui HS-Y; Wali B; Ellis M; Huerta C; Bechnack K
  • Antibody binding and neutralization of live SARS-CoV-2 variants including BA.4/5 following booster vaccination of patients with B-cell malignancies.
    Cancer Res Commun Volume: 2 Page(s): 1684 - 1692
    12/01/2022 Authors: Chang A; Akhtar A; Lai L; Orellana-Noia VM; Linderman SL; McCook-Veal AA; Switchenko JM; Saini M; Valanparambil RM; Blum KA
  • Neutralizing antibody responses in patients hospitalized with SARS-CoV-2 Delta or Omicron infection.
    J Clin Invest Volume: 132
    12/01/2022 Authors: Linderman SL; Lai L; Bocangel Gamarra EL; Lau MS; Edupuganti S; Surie D; Tenforde MW; Chappell JD; Mohr NM; Gibbs KW
  • Protection against SARS-CoV-2 Omicron BA.1 variant challenge in macaques by prime-boost vaccination with Ad26.COV2.S and SpFN.
    Sci Adv Volume: 8 Page(s): eade4433
    11/25/2022 Authors: Yu J; Thomas PV; McMahan K; Jacob-Dolan C; Liu J; He X; Hope D; Martinez EJ; Chen W-H; Sciacca M
  • A multispecific antibody prevents immune escape and confers pan-SARS-CoV-2 neutralization.
    bioRxiv
    11/21/2022 Authors: Misasi J; Wei RR; Wang L; Pegu A; Wei C-J; Oloniniyi OK; Zhou T; Moliva JI; Zhao B; Choe M
  • Antibody Response to COVID-19 mRNA Vaccine in Patients With Lung Cancer After Primary Immunization and Booster: Reactivity to the SARS-CoV-2 WT Virus and Omicron Variant.
    J Clin Oncol Volume: 40 Page(s): 3808 - 3816
    11/20/2022 Authors: Valanparambil RM; Carlisle J; Linderman SL; Akthar A; Millett RL; Lai L; Chang A; McCook-Veal AA; Switchenko J; Nasti TH
  • mRNA bivalent booster enhances neutralization against BA.2.75.2 and BQ.1.1.
    bioRxiv
    11/01/2022 Authors: Davis-Gardner ME; Lai L; Wali B; Samaha H; Solis D; Lee M; Porter-Morrison A; Hentenaar IT; Yamamoto F; Godbole S
  • Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
    bioRxiv
    10/24/2022 Authors: Patel A; Kumar S; Lai L; Chakravarthy C; Valanparambil R; Reddy ES; Gottimukkala K; Bajpai P; Raju DR; Edara VV
  • Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody.
    Sci Adv Volume: 8 Page(s): eadd2032
    10/07/2022 Authors: Kumar S; Patel A; Lai L; Chakravarthy C; Valanparambil R; Reddy ES; Gottimukkala K; Davis-Gardner ME; Edara VV; Linderman S
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  • TLR7 and RIG-I dual-adjuvant loaded nanoparticles drive broadened and synergistic responses in dendritic cells in vitro and generate unique cellular immune responses in influenza vaccination.
    J Control Release Volume: 330 Page(s): 866 - 877
    02/10/2021 Authors: Toy R; Keenum MC; Pradhan P; Phang K; Chen P; Chukwu C; Nguyen LAH; Liu J; Jain S; Kozlowski G
  • Infection and mRNA-1273 vaccine antibodies neutralize SARS-CoV-2 UK variant.
    medRxiv
    02/05/2021 Authors: Edara VV; Floyd K; Lai L; Gardner M; Hudson W; Piantadosi A; Waggoner JJ; Babiker A; Ahmed R; Xie X
  • Comprehensive analysis of COVID-19 during pregnancy.
    Biochem Biophys Res Commun Volume: 538 Page(s): 180 - 186
    01/29/2021 Authors: Moore KM; Suthar MS
  • The amphibian peptide Yodha is virucidal for Zika and dengue viruses.
    Sci Rep Volume: 11 Page(s): 602
    01/12/2021 Authors: Lee SH; Kim EH; O'neal JT; Dale G; Holthausen DJ; Bowen JR; Quicke KM; Skountzou I; Gopal S; George S
  • Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination.
    N Engl J Med Volume: 384 Page(s): 80 - 82
    01/07/2021 Authors: Widge AT; Rouphael NG; Jackson LA; Anderson EJ; Roberts PC; Makhene M; Chappell JD; Denison MR; Stevens LJ; Pruijssers AJ
  • Original antigenic sin responses to Betacoronavirus spike proteins are observed in a mouse model, but are not apparent in children following SARS-CoV-2 infection.
    PLoS One Volume: 16 Page(s): e0256482
    01/01/2021 Authors: Lapp SA; Edara VV; Lu A; Lai L; Hussaini L; Chahroudi A; Anderson LJ; Suthar MS; Anderson EJ; Rostad CA
  • Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults.
    N Engl J Med Volume: 383 Page(s): 2427 - 2438
    12/17/2020 Authors: Anderson EJ; Rouphael NG; Widge AT; Jackson LA; Roberts PC; Makhene M; Chappell JD; Denison MR; Stevens LJ; Pruijssers AJ
  • Development of a Rapid Focus Reduction Neutralization Test Assay for Measuring SARS-CoV-2 Neutralizing Antibodies.
    Curr Protoc Immunol Volume: 131 Page(s): e116
    12/01/2020 Authors: Vanderheiden A; Edara VV; Floyd K; Kauffman RC; Mantus G; Anderson E; Rouphael N; Edupuganti S; Shi P-Y; Menachery VD
  • Quantitative SARS-CoV-2 Serology in Children With Multisystem Inflammatory Syndrome (MIS-C).
    Pediatrics Volume: 146
    12/01/2020 Authors: Rostad CA; Chahroudi A; Mantus G; Lapp SA; Teherani M; Macoy L; Tarquinio KM; Basu RK; Kao C; Linam WM
  • SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity.
    Nat Commun Volume: 11 Page(s): 6013
    11/26/2020 Authors: Zhang L; Jackson CB; Mou H; Ojha A; Peng H; Quinlan BD; Rangarajan ES; Pan A; Vanderheiden A; Suthar MS
  • Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation.
    Nat Commun Volume: 11 Page(s): 5413
    10/27/2020 Authors: Hurlburt NK; Seydoux E; Wan Y-H; Edara VV; Stuart AB; Feng J; Suthar MS; McGuire AT; Stamatatos L; Pancera M
  • Prevalence of SARS-CoV-2 Antibodies in Pediatric Health Care Workers in Atlanta, Georgia
    Volume: 76 Page(s): S124 - S125
    10/01/2020 Authors: Morris CR; Camacho-Gonzalez A; Chen C; Heilman S; Iyer S; Mantus G; Sanchez T; Sullivan P; Suthar M; Wrammert J
  • COVID-19 convalescent plasma clears SARS-CoV-2 refractory to remdesivir in an infant with congenital heart disease.
    Blood Adv Volume: 4 Page(s): 4278 - 4281
    09/22/2020 Authors: Rodriguez Z; Shane AL; Verkerke H; Lough C; Zimmerman MG; Suthar M; Wrammert J; MacDonald H; Wolf M; Clarke S
  • Type I and Type III Interferons Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures.
    J Virol Volume: 94
    09/15/2020 Authors: Vanderheiden A; Ralfs P; Chirkova T; Upadhyay AA; Zimmerman MG; Bedoya S; Aoued H; Tharp GM; Pellegrini KL; Manfredi C
  • Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis.
    bioRxiv
    08/26/2020 Authors: Johnson BA; Xie X; Kalveram B; Lokugamage KG; Muruato A; Zou J; Zhang X; Juelich T; Smith JK; Zhang L
  • Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients.
    Cell Rep Med Volume: 1 Page(s): 100040
    06/23/2020 Authors: Suthar MS; Zimmerman MG; Kauffman RC; Mantus G; Linderman SL; Hudson WH; Vanderheiden A; Nyhoff L; Davis CW; Adekunle O
  • Long-term alterations in brain and behavior after postnatal Zika virus infection in infant macaques.
    Nat Commun Volume: 11 Page(s): 2534
    05/21/2020 Authors: Raper J; Kovacs-Balint Z; Mavigner M; Gumber S; Burke MW; Habib J; Mattingly C; Fair D; Earl E; Feczko E
  • Rapid generation of neutralizing antibody responses in COVID-19 patients.
    medRxiv
    05/08/2020 Authors: Suthar MS; Zimmerman M; Kauffman R; Mantus G; Linderman S; Vanderheiden A; Nyhoff L; Davis C; Adekunle S; Affer M
  • CD8+T cell intrinsic MAVS promotes antigen-specific responses and mitochondrial metabolism during West Nile Virus neuroinvasive disease
    Volume: 204
    05/01/2020 Authors: Vanderheiden A; Aguilar-Valenzuela R; Verkerke H; Price M; Boss JM; Grakoui A; Suthar MS
  • Cross-reactive dengue immune complexes modulate innate antiviral responses to Zika virus infection in human placental macrophages
    Volume: 204
    05/01/2020 Authors: Zimmerman MG; Eddins D; Muhammad A; Register E; Kauffman R; Cordes S; Jean V; Haddad L; Wrammert J; Suthar MS
  • Cross-Reactive Antibodies during Zika Virus Infection: Protection, Pathogenesis, and Placental Seeding.
    Cell Host Microbe Volume: 27 Page(s): 14 - 24
    01/08/2020 Authors: Zimmerman MG; Wrammert J; Suthar MS
  • STAT5: a Target of Antagonism by Neurotropic Flaviviruses.
    J Virol Volume: 93
    12/01/2019 Authors: Zimmerman MG; Bowen JR; McDonald CE; Young E; Baric RS; Pulendran B; Suthar MS
  • West Nile Virus Infection Blocks Inflammatory Response and T Cell Costimulatory Capacity of Human Monocyte-Derived Dendritic Cells.
    J Virol Volume: 93
    12/01/2019 Authors: Zimmerman MG; Bowen JR; McDonald CE; Pulendran B; Suthar MS
  • Strong TH1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy.
    Sci Transl Med Volume: 11
    11/20/2019 Authors: Chamcha V; Reddy PBJ; Kannanganat S; Wilkins C; Gangadhara S; Velu V; Green R; Law GL; Chang J; Bowen JR
  • RNA Helicase LGP2 Negatively Regulates RIG-I Signaling by Preventing TRIM25-Mediated Caspase Activation and Recruitment Domain Ubiquitination.
    J Interferon Cytokine Res Volume: 39 Page(s): 669 - 683
    11/01/2019 Authors: Quicke KM; Kim KY; Horvath CM; Suthar MS
  • Acetaminophen Intoxication Rapidly Induces Apoptosis of Intestinal Crypt Stem Cells and Enhances Intestinal Permeability.
    Hepatol Commun Volume: 3 Page(s): 1435 - 1449
    11/01/2019 Authors: Chopyk DM; Stuart JD; Zimmerman MG; Wen J; Gumber S; Suthar MS; Thapa M; Czaja MJ; Grakoui A
  • The Effect of Anticoagulants, Temperature, and Time on the Human Plasma Metabolome and Lipidome from Healthy Donors as Determined by Liquid Chromatography-Mass Spectrometry.
    Biomolecules Volume: 9
    05/23/2019 Authors: Khadka M; Todor A; Maner-Smith KM; Colucci JK; Tran V; Gaul DA; Anderson EJ; Natrajan MS; Rouphael N; Mulligan MJ
  • West Nile Virus-Inclusive Single-Cell RNA Sequencing Reveals Heterogeneity in the Type I Interferon Response within Single Cells.
    J Virol Volume: 93
    03/15/2019 Authors: O'Neal JT; Upadhyay AA; Wolabaugh A; Patel NB; Bosinger SE; Suthar MS
  • Cell-type specificity and functional redundancy of RIG-I-like receptors in innate immune sensing of Coxsackievirus B3 and encephalomyocarditis virus.
    Virology Volume: 528 Page(s): 7 - 18
    02/01/2019 Authors: Francisco E; Suthar M; Gale M; Rosenfeld AB; Racaniello VR
  • Dendritic cell-associated MAVS is required to control West Nile virus replication and ensuing humoral immune responses.
    PLoS One Volume: 14 Page(s): e0218928
    01/01/2019 Authors: Roe K; Giordano D; Young LB; Draves KE; Holder U; Suthar MS; Gale M; Clark EA
  • Pre-Existing Dengue Immunity Drives a DENV-Biased Plasmablast Response in ZIKV-Infected Patient.
    Viruses Volume: 11
    12/29/2018 Authors: Bhaumik SK; Priyamvada L; Kauffman RC; Lai L; Natrajan MS; Cho A; Rouphael N; Suthar MS; Mulligan MJ; Wrammert J
  • Cross-Reactive Dengue Virus Antibodies Augment Zika Virus Infection of Human Placental Macrophages.
    Cell Host Microbe Volume: 24 Page(s): 731 - 742.e6
    11/14/2018 Authors: Zimmerman MG; Quicke KM; O'Neal JT; Arora N; Machiah D; Priyamvada L; Kauffman RC; Register E; Adekunle O; Swieboda D
  • Taking the defensive: Immune control of Zika virus infection.
    Virus Res Volume: 254 Page(s): 21 - 26
    08/02/2018 Authors: Bowen JR; Zimmerman MG; Suthar MS
  • Dynamics of Tissue-Specific CD8+ T Cell Responses during West Nile Virus Infection.
    J Virol Volume: 92
    05/15/2018 Authors: Aguilar-Valenzuela R; Netland J; Seo Y-J; Bevan MJ; Grakoui A; Suthar MS
  • Postnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques.
    Sci Transl Med Volume: 10
    04/04/2018 Authors: Mavigner M; Raper J; Kovacs-Balint Z; Gumber S; O'Neal JT; Bhaumik SK; Zhang X; Habib J; Mattingly C; McDonald CE
  • Editorial overview: Viral immunology: Generating immunity to diverse viral pathogens.
    Curr Opin Virol Volume: 28 Page(s): viii - x
    02/01/2018 Authors: Hickman HD; Suthar MS
  • Humoral Immune Responses Against Zika Virus Infection and the Importance of Preexisting Flavivirus Immunity.
    J Infect Dis Volume: 216 Page(s): S906 - S911
    12/16/2017 Authors: Priyamvada L; Suthar MS; Ahmed R; Wrammert J
  • Transgenic West Nile Virus virus-specific CDS+ T cells provide insights on activation patterns and protective role of cytotoxic T cells during infection
    Volume: 198
    05/01/2017 Authors: Aguilar-Valenzuela R; Seo Y-J; Grakoui A; Suthar MS
  • West Nile virus antagonism of a RIG-I, type I interferon, and STAT5 signaling axis in human dendritic cells
    Volume: 198
    05/01/2017 Authors: Bowen JR; McDonald CE; Suthar MS
  • Negative regulators of the RIG-I-like receptor signaling pathway.
    Eur J Immunol Volume: 47 Page(s): 615 - 628
    04/01/2017 Authors: Quicke KM; Diamond MS; Suthar MS
  • Zika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic Cells.
    PLoS Pathog Volume: 13 Page(s): e1006164
    02/01/2017 Authors: Bowen JR; Quicke KM; Maddur MS; O'Neal JT; McDonald CE; Fedorova NB; Puri V; Shabman RS; Pulendran B; Suthar MS
  • Jak Inhibitors Modulate Production of Replication-Competent Zika Virus in Human Hofbauer, Trophoblasts, and Neuroblastoma cells.
    Pathog Immun Volume: 2 Page(s): 199 - 218
    01/01/2017 Authors: Gavegnano C; Bassit LC; Cox BD; Hsiao H-M; Johnson EL; Suthar M; Chakraborty R; Schinazi RF
  • Local Cellular and Cytokine Cues in the Spleen Regulate In Situ T Cell Receptor Affinity, Function, and Fate of CD8+ T Cells.
    Immunity Volume: 45 Page(s): 988 - 998
    11/15/2016 Authors: Seo Y-J; Jothikumar P; Suthar MS; Zhu C; Grakoui A
  • N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection.
    Cell Host Microbe Volume: 20 Page(s): 654 - 665
    11/09/2016 Authors: Gokhale NS; McIntyre ABR; McFadden MJ; Roder AE; Kennedy EM; Gandara JA; Hopcraft SE; Quicke KM; Vazquez C; Willer J
  • Prolonged activation of innate antiviral gene signature after childbirth is determined by IFNL3 genotype.
    Proc Natl Acad Sci U S A Volume: 113 Page(s): 10678 - 10683
    09/20/2016 Authors: Price AA; Tedesco D; Prasad MR; Workowski KA; Walker CM; Suthar MS; Honegger JR; Grakoui A
  • Zika Virus Infects Human Placental Macrophages.
    Cell Host Microbe Volume: 20 Page(s): 83 - 90
    07/13/2016 Authors: Quicke KM; Bowen JR; Johnson EL; McDonald CE; Ma H; O'Neal JT; Rajakumar A; Wrammert J; Rimawi BH; Pulendran B
  • Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus.
    Proc Natl Acad Sci U S A Volume: 113 Page(s): 7852 - 7857
    07/12/2016 Authors: Priyamvada L; Quicke KM; Hudson WH; Onlamoon N; Sewatanon J; Edupuganti S; Pattanapanyasat K; Chokephaibulkit K; Mulligan MJ; Wilson PC
  • A complement-microglial axis drives synapse loss during virus-induced memory impairment.
    Nature Volume: 534 Page(s): 538 - 543
    06/23/2016 Authors: Vasek MJ; Garber C; Dorsey D; Durrant DM; Bollman B; Soung A; Yu J; Perez-Torres C; Frouin A; Wilton DK
  • Systems biology: A tool for charting the antiviral landscape.
    Virus Res Volume: 218 Page(s): 2 - 9
    06/15/2016 Authors: Bowen JR; Ferris MT; Suthar MS
  • The role of the RIG-I like receptors in mediating CD8+T cell immunity during virus infection
    Volume: 196
    05/01/2016 Authors: Aguilar-Valenzuela RA; Ma DY; Suthar MS
  • Mechanisms of LGP2-dependent regulation of RIG-I signaling and dendritic cell activation
    Volume: 196
    05/01/2016 Authors: Quicke K; Suthar MS
  • A systems biology approach unravels the host response to West Nile virus infection in human dendritic cells
    Volume: 196
    05/01/2016 Authors: Bowen JR; Suthar MS
  • Ly6C(hi) monocytes control acute Ross River virus infection through an IRF7-dependent mechanism that can be counteracted by determinants in nsP1
    Volume: 196
    05/01/2016 Authors: Haist KC; Burrack KS; Diamond MS; Suthar MS; Morrison TE
  • S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3.
    Nat Immunol Volume: 17 Page(s): 514 - 522
    05/01/2016 Authors: Wang F; Alain T; Szretter KJ; Stephenson K; Pol JG; Atherton MJ; Hoang H-D; Fonseca BD; Zakaria C; Chen L
  • Mechanisms of innate immune evasion in re-emerging RNA viruses.
    Curr Opin Virol Volume: 12 Page(s): 26 - 37
    06/01/2015 Authors: Ma DY; Suthar MS
  • Liver fibrosis occurs through dysregulation of MyD88-dependent innate B-cell activity.
    Hepatology Volume: 61 Page(s): 2067 - 2079
    06/01/2015 Authors: Thapa M; Chinnadurai R; Velazquez VM; Tedesco D; Elrod E; Han J-H; Sharma P; Ibegbu C; Gewirtz A; Anania F
  • Genetic diversity in the collaborative cross model recapitulates human West Nile virus disease outcomes.
    mBio Volume: 6 Page(s): e00493 - e00415
    05/05/2015 Authors: Graham JB; Thomas S; Swarts J; McMillan AA; Ferris MT; Suthar MS; Treuting PM; Ireton R; Gale M; Lund JM
  • Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development.
    Hepatology Volume: 61 Page(s): 843 - 856
    03/01/2015 Authors: Velazquez VM; Uebelhoer LS; Thapa M; Ibegbu CC; Courtney C; Bosinger SE; Magliocca JF; Adams AB; Kirk AD; Knechtle SJ
  • Systems analysis of West Nile virus infection.
    Curr Opin Virol Volume: 6 Page(s): 70 - 75
    06/01/2014 Authors: Suthar MS; Pulendran B
  • Deficient IFN signaling by myeloid cells leads to MAVS-dependent virus-induced sepsis.
    PLoS Pathog Volume: 10 Page(s): e1004086
    04/01/2014 Authors: Pinto AK; Ramos HJ; Wu X; Aggarwal S; Shrestha B; Gorman M; Kim KY; Suthar MS; Atkinson JP; Gale M
  • The essential, nonredundant roles of RIG-I and MDA5 in detecting and controlling West Nile virus infection.
    J Virol Volume: 87 Page(s): 11416 - 11425
    11/01/2013 Authors: Errett JS; Suthar MS; McMillan A; Diamond MS; Gale M
  • Pattern recognition receptor MDA5 modulates CD8+ T cell-dependent clearance of West Nile virus from the central nervous system.
    J Virol Volume: 87 Page(s): 11401 - 11415
    11/01/2013 Authors: Lazear HM; Pinto AK; Ramos HJ; Vick SC; Shrestha B; Suthar MS; Gale M; Diamond MS
  • The innate immune playbook for restricting West Nile virus infection.
    Viruses Volume: 5 Page(s): 2643 - 2658
    10/30/2013 Authors: Quicke KM; Suthar MS
  • Innate immune sensing of flaviviruses.
    PLoS Pathog Volume: 9 Page(s): e1003541
    09/01/2013 Authors: Suthar MS; Aguirre S; Fernandez-Sesma A
  • RIG-I receptor regulation of T cell immunity during virus infection
    Volume: 190
    05/01/2013 Authors: Suthar M; Ramos H; Brassil M; Netland J; Chappell C; Blahnik G; McMillan A; Diamond M; Clark E; Bevan M
  • IKK epsilon is targeted by pathogenic West Nile virus to evade host immune control
    Volume: 190
    05/01/2013 Authors: Huang A; Perwitasari O; Ramos H; Suthar M; Brassil M; Blahnik G; Gale M
  • CD22 is required for protection against West Nile virus Infection.
    J Virol Volume: 87 Page(s): 3361 - 3375
    03/01/2013 Authors: Ma DY; Suthar MS; Kasahara S; Gale M; Clark EA
  • West Nile virus infection and immunity.
    Nat Rev Microbiol Volume: 11 Page(s): 115 - 128
    02/01/2013 Authors: Suthar MS; Diamond MS; Gale M
  • A systems biology approach reveals that tissue tropism to West Nile virus is regulated by antiviral genes and innate immune cellular processes.
    PLoS Pathog Volume: 9 Page(s): e1003168
    02/01/2013 Authors: Suthar MS; Brassil MM; Blahnik G; McMillan A; Ramos HJ; Proll SC; Belisle SE; Katze MG; Gale M
  • IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling.
    PLoS Pathog Volume: 9 Page(s): e1003118
    01/01/2013 Authors: Lazear HM; Lancaster A; Wilkins C; Suthar MS; Huang A; Vick SC; Clepper L; Thackray L; Brassil MM; Virgin HW
  • The RIG-I-like receptor LGP2 controls CD8(+) T cell survival and fitness.
    Immunity Volume: 37 Page(s): 235 - 248
    08/24/2012 Authors: Suthar MS; Ramos HJ; Brassil MM; Netland J; Chappell CP; Blahnik G; McMillan A; Diamond MS; Clark EA; Bevan MJ
  • Infectious clones of novel lineage 1 and lineage 2 West Nile virus strains WNV-TX02 and WNV-Madagascar.
    J Virol Volume: 86 Page(s): 7704 - 7709
    07/01/2012 Authors: Suthar MS; Brassil MM; Blahnik G; Gale M
  • IL-1 signaling promotes CNS-intrinsic immune control of West Nile virus infection.
    PLoS Pathog Volume: 8 Page(s): e1003039
    01/01/2012 Authors: Ramos HJ; Lanteri MC; Blahnik G; Negash A; Suthar MS; Brassil MM; Sodhi K; Treuting PM; Busch MP; Norris PJ
  • IL-1 signaling and the NLRP3 Inflammasome are required for CNS-specific protective immunity against West Nile Virus
    Volume: 56 Page(s): 11 - 11
    10/01/2011 Authors: Ramos HJ; Suthar M; Negash A; Blahnick G; Brassil M; Gale M
  • A Systems Biology approach to defining the host immune response to West Nile virus infection
    Volume: 56 Page(s): 48 - 49
    10/01/2011 Authors: Suthar MS; Brassil M; Proll S; Belisle S; Katze MG; Gale M
  • Interferon regulatory factor-1 (IRF-1) shapes both innate and CD8(+) T cell immune responses against West Nile virus infection.
    PLoS Pathog Volume: 7 Page(s): e1002230
    09/01/2011 Authors: Brien JD; Daffis S; Lazear HM; Cho H; Suthar MS; Gale M; Diamond MS
  • Nitric oxide controls an inflammatory-like Ly6C(hi)PDCA1+ DC subset that regulates Th1 immune responses.
    J Leukoc Biol Volume: 89 Page(s): 443 - 455
    03/01/2011 Authors: Giordano D; Li C; Suthar MS; Draves KE; Ma DY; Gale M; Clark EA
  • The innate immune adaptor molecule MyD88 restricts West Nile virus replication and spread in neurons of the central nervous system.
    J Virol Volume: 84 Page(s): 12125 - 12138
    12/01/2010 Authors: Szretter KJ; Daffis S; Patel J; Suthar MS; Klein RS; Gale M; Diamond MS
  • Rabies virus infection induces type I interferon production in an IPS-1 dependent manner while dendritic cell activation relies on IFNAR signaling.
    PLoS Pathog Volume: 6 Page(s): e1001016
    07/22/2010 Authors: Faul EJ; Wanjalla CN; Suthar MS; Gale M; Wirblich C; Schnell MJ
  • Modulation of type I IFN induction by a virulence determinant within the alphavirus nsP1 protein.
    Virology Volume: 399 Page(s): 1 - 10
    03/30/2010 Authors: Cruz CC; Suthar MS; Montgomery SA; Shabman R; Simmons J; Johnston RE; Morrison TE; Heise MT
  • IPS-1 is essential for the control of West Nile virus infection and immunity.
    PLoS Pathog Volume: 6 Page(s): e1000757
    02/05/2010 Authors: Suthar MS; Ma DY; Thomas S; Lund JM; Zhang N; Daffis S; Rudensky AY; Bevan MJ; Clark EA; Kaja M-K
  • Long double-stranded RNA induces an antiviral response independent of IFN regulatory factor 3, IFN-beta promoter stimulator 1, and IFN.
    J Immunol Volume: 183 Page(s): 6545 - 6553
    11/15/2009 Authors: DeWitte-Orr SJ; Mehta DR; Collins SE; Suthar MS; Gale M; Mossman KL
  • Induction of IFN-beta and the innate antiviral response in myeloid cells occurs through an IPS-1-dependent signal that does not require IRF-3 and IRF-7.
    PLoS Pathog Volume: 5 Page(s): e1000607
    10/01/2009 Authors: Daffis S; Suthar MS; Szretter KJ; Gale M; Diamond MS
  • Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses.
    Cell Microbiol Volume: 11 Page(s): 880 - 888
    06/01/2009 Authors: Suthar MS; Gale M; Owen DM
  • Measure and countermeasure: type I IFN (IFN-alpha/beta) antiviral response against West Nile virus.
    J Innate Immun Volume: 1 Page(s): 435 - 445
    01/01/2009 Authors: Daffis S; Suthar MS; Gale M; Diamond MS
  • Toll-like receptor 3 has a protective role against West Nile virus infection.
    J Virol Volume: 82 Page(s): 10349 - 10358
    11/01/2008 Authors: Daffis S; Samuel MA; Suthar MS; Gale M; Diamond MS
  • Interferon regulatory factor IRF-7 induces the antiviral alpha interferon response and protects against lethal West Nile virus infection.
    J Virol Volume: 82 Page(s): 8465 - 8475
    09/01/2008 Authors: Daffis S; Samuel MA; Suthar MS; Keller BC; Gale M; Diamond MS
  • Differential induction of type I interferon responses in myeloid dendritic cells by mosquito and mammalian-cell-derived alphaviruses.
    J Virol Volume: 81 Page(s): 237 - 247
    01/01/2007 Authors: Shabman RS; Morrison TE; Moore C; White L; Suthar MS; Hueston L; Rulli N; Lidbury B; Ting JP-Y; Mahalingam S
  • Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants.
    PLoS Med Volume: 3 Page(s): e525
    12/01/2006 Authors: Deming D; Sheahan T; Heise M; Yount B; Davis N; Sims A; Suthar M; Harkema J; Whitmore A; Pickles R
  • Ross river virus evasion of type I interferons
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Volume: 73 Page(s): 193 - 193
    12/01/2005 Authors: Shabman RS; Morrison TE; White L; Suthar MS; Madric K; Mahalingam S; Lidburyl B; Moore C; Heise MT
  • Identification of adult mouse neurovirulence determinants of the Sindbis virus strain AR86.
    J Virol Volume: 79 Page(s): 4219 - 4228
    04/01/2005 Authors: Suthar MS; Shabman R; Madric K; Lambeth C; Heise MT
  • Purification and characterization of hepatitis C virus non-structural protein 5A expressed in Escherichia coli.
    Protein Expr Purif Volume: 37 Page(s): 144 - 153
    09/01/2004 Authors: Huang L; Sineva EV; Hargittai MRS; Sharma SD; Suthar M; Raney KD; Cameron CE
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