Mehul Suthar
Academic Appointment
- Adjunct Faculty, Microbiology and Immunology, Emory University
- Assistant Professor, Department of Pediatrics, Emory University
- Emory Vaccine Center Member, Emory University
Education
Degrees
- PhD from University of North Carolina-Chapel Hill
- BS from Pennsylvania State University, University Park
Research
Publications
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Altered baseline immunological state and impaired immune response to SARS-CoV-2 mRNA vaccination in lung transplant recipients.
Cell Rep Med Volume: 6 Page(s): 102050
04/15/2025 Authors: Hu M; Oliveira APBN; Fang Z; Feng Y; Miranda M; Kowli S; Arunachalam PS; Vasudevan G; Hui HS-Y; Grifoni A -
SARS-CoV-2: The Interplay Between Evolution and Host Immunity.
Annu Rev Immunol Volume: 43 Page(s): 29 - 55
04/01/2025 Authors: Case JB; Jain S; Suthar MS; Diamond MS -
The furin cleavage site is required for pathogenesis, but not transmission of SARS-CoV-2.
bioRxiv
03/11/2025 Authors: Morgan AL; Vu MN; Zhou Y; Lokugamage KG; Meyers WM; Alvarado RE; Ahearn Y; Estes LK; Plante JA; Johnson BA -
The KP.2-adapted COVID-19 vaccine improves neutralising activity against the XEC variant.
Lancet Infect Dis Volume: 25 Page(s): e122 - e123
03/01/2025 Authors: Suthar MS; Manning KE; Ellis ML; Jain S; Bechnak K; Vander Velden J; Laboune F; Henry AR; Godbole S; Kim S -
Longitudinal Surveillance of COVID-19 Antibodies in Pediatric Healthcare Workers.
Vaccines (Basel) Volume: 13
02/07/2025 Authors: Hatabah D; Gupta SL; Mantus G; Sullivan P; Heilman S; Camacho-Gonzalez A; Leake D; Le M; Griffiths M; Norwood C -
A Phase 1 randomized trial of homologous and heterologous filovirus vaccines with a late booster dose.
NPJ Vaccines Volume: 9 Page(s): 255
12/23/2024 Authors: Rostad CA; Yildirim I; Kao C; Yi J; Kamidani S; Peters E; Stephens K; Gibson T; Hsiao H-M; Singh K -
A Global Collaborative Comparison of SARS-CoV-2 Antigenicity Across 15 Laboratories.
Viruses Volume: 16
12/18/2024 Authors: Brangel P; Tureli S; Mhlemann B; Liechti N; Zysset D; Engler O; Hunger-Glaser I; Ghiga I; Mattiuzzo G; Eckerle I -
Tissue-resident memory T cells contribute to protection against heterologous SARS-CoV-2 challenge.
JCI Insight Volume: 9
12/06/2024 Authors: Odle A; Kar M; Verma AK; Sariol A; Meyerholz DK; Suthar MS; Wong L-YR; Perlman S -
Corrigendum to "Incidence of SARS-CoV-2 seropositivity in pediatric healthcare workers prior to widespread vaccination: A 5-month longitudinal cohort study" [Internation Journal of Infectious Diseases, volume 144 (2024) 107064].
Int J Infect Dis Volume: 149 Page(s): 107278
12/01/2024 Authors: Griffiths M; Hatabah D; Sullivan P; Mantus G; Sanchez T; Zlotorzynska M; Heilman S; Camacho-Gonzalez A; Leake D; Korman R -
Enhanced D614G and Omicron Variants Antibody Persistence in Infants at 2 Months of Age Following Maternal mRNA Booster Vaccination During Pregnancy or Postpartum.
Pediatr Infect Dis J Volume: 43 Page(s): 1065 - 1073
11/01/2024 Authors: Munoz FM; Beigi R; Posavad CM; Kelly C; Badell ML; Bunge K; Mulligan MJ; Parameswaran L; Richardson BA; Olsen-Chen C -
Divergence of variant antibodies following SARS-CoV-2 booster vaccines in myeloma and impact of hybrid immunity.
NPJ Vaccines Volume: 9 Page(s): 201
10/27/2024 Authors: Moreno A; Manning K; Azeem MI; Nooka AK; Ellis M; Manalo RJ; Switchenko JM; Wali B; Kaufman JL; Hofmeister CC -
Immunogenicity and efficacy of XBB.1.5 rS vaccine against the EG.5.1 variant of SARS-CoV-2 in Syrian hamsters.
J Virol Volume: 98 Page(s): e0052824
10/22/2024 Authors: Soudani N; Bricker TL; Darling T; Seehra K; Patel N; Guebre-Xabier M; Smith G; Davis-Gardner M; Suthar MS; Ellebedy AH -
A multispecific antibody against SARS-CoV-2 prevents immune escape in vitro and confers prophylactic protection in vivo.
Sci Transl Med Volume: 16 Page(s): eado9026
10/09/2024 Authors: Misasi J; Wei RR; Wang L; Pegu A; Wei C-J; Oloniniyi OK; Zhou T; Moliva JI; Zhao B; Choe M -
Mucosal adenovirus vaccine boosting elicits IgA and durably prevents XBB.1.16 infection in nonhuman primates.
Nat Immunol Volume: 25 Page(s): 1913 - 1927
10/01/2024 Authors: Gagne M; Flynn BJ; Andrew SF; Marquez J; Flebbe DR; Mychalowych A; Lamb E; Davis-Gardner ME; Burnett MR; Serebryannyy LA -
Efficacy of late-onset antiviral treatment in immunocompromised hosts with persistent SARS-CoV-2 infection.
J Virol Volume: 98 Page(s): e0090524
09/17/2024 Authors: Lieber CM; Kang H-J; Sobolik EB; Sticher ZM; Ngo VL; Gewirtz AT; Kolykhalov AA; Natchus MG; Greninger AL; Suthar MS -
CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment.
Sci Adv Volume: 10 Page(s): eadp2636
08/23/2024 Authors: Kar M; Johnson KEE; Vanderheiden A; Elrod EJ; Floyd K; Geerling E; Stone ET; Salinas E; Banakis S; Wang W -
Variant-proof high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways.
Nat Commun Volume: 15 Page(s): 6894
08/12/2024 Authors: Gagne M; Flynn BJ; Honeycutt CC; Flebbe DR; Andrew SF; Provost SJ; McCormick L; Van Ry A; McCarthy E; Todd J-PM -
Eosinophils protect against SARS-CoV-2 following a vaccine breakthrough infection.
bioRxiv
08/10/2024 Authors: Moore KM; Foster SL; Kar M; Floyd KA; Elrod EJ; Williams ME; Velden JV; Ellis M; Malik A; Wali B -
Patients taking benralizumab, dupilumab, or mepolizumab have lower postvaccination SARS-CoV-2 immunity.
J Allergy Clin Immunol Volume: 154 Page(s): 435 - 446
08/01/2024 Authors: Runnstrom MC; Lamothe PA; Faliti CE; Cheedarla N; Moreno A; Suthar MS; Nahata R; Ravindran M; Haddad NS; Morrison-Porter A -
Incidence of SARS-CoV-2 seropositivity in pediatric healthcare workers prior to widespread vaccination: A 5-month longitudinal cohort study.
Int J Infect Dis Volume: 144 Page(s): 107064
07/01/2024 Authors: Griffiths M; Hatabah D; Sullivan P; Mantus G; Sanchez T; Zlotorzynska M; Heilman S; Camacho-Gonzalez A; Leake D; Korman R -
Efficacy of late-onset antiviral treatment in immune-compromised hosts with persistent SARS-CoV-2 infection.
bioRxiv
05/23/2024 Authors: Lieber CM; Kang H-J; Sobolik EB; Sticher ZM; Ngo VL; Gewirtz AT; Kolykhalov AA; Natchus MG; Greninger AL; Suthar MS -
Comparative analysis of SARS-CoV-2 neutralization titers reveals consistency between human and animal model serum and across assays.
Sci Transl Med Volume: 16 Page(s): eadl1722
05/15/2024 Authors: Mhlemann B; Wilks SH; Baracco L; Bekliz M; Carreo JM; Corman VM; Davis-Gardner ME; Dejnirattisai W; Diamond MS; Douek DC -
Single-cell analysis reveals an antiviral network that controls Zika virus infection in human dendritic cells.
J Virol Volume: 98 Page(s): e0019424
05/14/2024 Authors: Moore KM; Pelletier A-N; Lapp S; Metz A; Tharp GK; Lee M; Bhasin SS; Bhasin M; Skaly R-P; Bosinger SE -
Durability of immune responses to SARS-CoV-2 infection and vaccination.
Semin Immunol Volume: 73 Page(s): 101884
05/01/2024 Authors: Suthar MS -
SARS-CoV-2 Viral Shedding and Rapid Antigen Test Performance - Respiratory Virus Transmission Network, November 2022-May 2023.
MMWR Morb Mortal Wkly Rep Volume: 73 Page(s): 365 - 371
04/25/2024 Authors: Smith-Jeffcoat SE; Mellis AM; Grijalva CG; Talbot HK; Schmitz J; Lutrick K; Ellingson KD; Stockwell MS; McLaren SH; Nguyen HQ -
AS03 adjuvant enhances the magnitude, persistence, and clonal breadth of memory B cell responses to a plant-based COVID-19 vaccine in humans.
Sci Immunol Volume: 9 Page(s): eadi8039
04/05/2024 Authors: Grigoryan L; Feng Y; Bellusci L; Lai L; Wali B; Ellis M; Yuan M; Arunachalam PS; Hu M; Kowli S -
Maternal COVID-19 Vaccination and Prevention of Symptomatic Infection in Infants.
Pediatrics Volume: 153
03/01/2024 Authors: Cardemil CV; Cao Y; Posavad CM; Badell ML; Bunge K; Mulligan MJ; Parameswaran L; Olson-Chen C; Novak RM; Brady RC -
Immunogenicity and efficacy of XBB.1.5 rS vaccine against EG.5.1 variant of SARS-CoV-2 in Syrian hamsters.
Res Sq
02/09/2024 Authors: Boon J; Soudani N; Bricker T; Darling T; Seehra K; Patel N; Guebre-Xabier M; Smith G; Suthar M; Ellebedy A -
XBB.1.5 monovalent booster improves antibody binding and neutralization against emerging SARS-CoV-2 Omicron variants.
bioRxiv
02/05/2024 Authors: Jain S; Kumar S; Lai L; Linderman S; Malik AA; Ellis ML; Godbole S; Solis D; Sahoo MK; Bechnak K -
Mucosal boosting enhances vaccine protection against SARS-CoV-2 in macaques.
Nature Volume: 626 Page(s): 385 - 391
02/01/2024 Authors: McMahan K; Wegmann F; Aid M; Sciacca M; Liu J; Hachmann NP; Miller J; Jacob-Dolan C; Powers O; Hope D -
CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment.
bioRxiv
01/24/2024 Authors: Kar M; Johnson KEE; Vanderheiden A; Elrod EJ; Floyd K; Geerling E; Stone ET; Salinas E; Banakis S; Wang W -
Single cell analysis reveals an antiviral network that controls Zika virus infection in human dendritic cells.
01/21/2024 Authors: Moore KM; Pelletier A-N; Lapp S; Metz A; Tharp GK; Lee M; Bhasin SS; Bhasin M; Skaly R-P; Bosinger SE -
BCG vaccination stimulates integrated organ immunity by feedback of the adaptive immune response to imprint prolonged innate antiviral resistance.
Nat Immunol Volume: 25 Page(s): 41 - 53
01/01/2024 Authors: Lee A; Floyd K; Wu S; Fang Z; Tan TK; Froggatt HM; Powers JM; Leist SR; Gully KL; Hubbard ML -
Durable immunity to SARS-CoV-2 in both lower and upper airways achieved with a gorilla adenovirus (GRAd) S-2P vaccine in non-human primates.
bioRxiv
11/22/2023 Authors: Moliva JI; Andrew SF; Flynn BJ; Wagner DA; Foulds KE; Gagne M; Flebbe DR; Lamb E; Provost S; Marquez J -
BA.5 bivalent booster vaccination enhances neutralization of XBB.1.5, XBB.1.16 and XBB.1.9 variants in patients with lung cancer.
NPJ Vaccines Volume: 8 Page(s): 179
11/21/2023 Authors: Valanparambil RM; Lai L; Johns MA; Davis-Gardner M; Linderman SL; McPherson TO; Chang A; Akhtar A; Gamarra ELB; Matia H -
Mucosal Adenoviral-vectored Vaccine Boosting Durably Prevents XBB.1.16 Infection in Nonhuman Primates.
bioRxiv
11/08/2023 Authors: Gagne M; Flynn BJ; Andrew SF; Flebbe DR; Mychalowych A; Lamb E; Davis-Gardner ME; Burnett MR; Serebryannyy LA; Lin BC -
Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS-CoV-2 infection and COVID-19 disease severity.
FASEB J Volume: 37 Page(s): e23220
11/01/2023 Authors: Tedbury PR; Manfredi C; Degenhardt F; Conway J; Horwath MC; McCracken C; Sorscher AJ; Moreau S; Wright C; Edwards C -
Efficacy of mRNA-1273 and Novavax ancestral or BA.1 spike booster vaccines against SARS-CoV-2 BA.5 infection in nonhuman primates.
Sci Immunol Volume: 8 Page(s): eadg7015
10/27/2023 Authors: Routhu NK; Stampfer SD; Lai L; Akhtar A; Tong X; Yuan D; Chicz TM; McNamara RP; Jakkala K; Davis-Gardner ME -
Infants and young children generate more durable antibody responses to SARS-CoV-2 infection than adults.
iScience Volume: 26 Page(s): 107967
10/20/2023 Authors: Joshi D; Nyhoff LE; Zarnitsyna VI; Moreno A; Manning K; Linderman S; Burrell AR; Stephens K; Norwood C; Mantus G -
Preclinical development of modified vaccinia virus Ankara vaccines against SARS-CoV-2 infections
Volume: 52 Page(s): 304 - 304
10/01/2023 Authors: Routhu NK; Gangadhara S; Lai L; Davis-Gardner ME; Floyd K; Shiferaw A; Bartsch YC; Fischinger S; Khoury G; Rahman SA -
Comparative Analysis of SARS-CoV-2 Antigenicity across Assays and in Human and Animal Model Sera.
bioRxiv
09/27/2023 Authors: Mhlemann B; Wilks SH; Baracco L; Bekliz M; Carreo JM; Corman VM; Davis-Gardner ME; Dejnirattisai W; Diamond MS; Douek DC -
Light chain of a public SARS-CoV-2 class-3 antibody modulates neutralization against Omicron.
Cell Rep Volume: 42 Page(s): 113150
09/26/2023 Authors: Patel A; Kumar S; Lai L; Keen M; Valanparambil R; Chakravarthy C; Laughlin Z; Frank F; Cheedarla N; Verkerke HP -
Divergence of variant binding/neutralizing antibodies following SARS-CoV-2 booster vaccines in myeloma: Impact of hybrid immunity.
Res Sq
09/21/2023 Authors: Moreno A; Manning K; Azeem MI; Nooka AK; Ellis M; Manalo RJ; Switchenko JM; Wali B; Kaufman JL; Hofmeister CC -
IFN- derived from nonsusceptible enterocytes acts on tuft cells to limit persistent norovirus.
Sci Adv Volume: 9 Page(s): eadi2562
09/15/2023 Authors: Ingle H; Makimaa H; Aggarwal S; Deng H; Foster L; Li Y; Kennedy EA; Peterson ST; Wilen CB; Lee S -
A wild boar cathelicidin peptide derivative inhibits severe acute respiratory syndrome coronavirus-2 and its drifted variants.
Sci Rep Volume: 13 Page(s): 14650
09/05/2023 Authors: von Beck T; Navarrete K; Arce NA; Gao M; Dale GA; Davis-Gardner ME; Floyd K; Mena Hernandez L; Mullick N; Vanderheiden A -
Atovaquone and Pibrentasvir Inhibit the SARS-CoV-2 Endoribonuclease and Restrict Infection In Vitro but Not In Vivo.
Viruses Volume: 15
08/30/2023 Authors: von Beck T; Mena Hernandez L; Zhou H; Floyd K; Suthar MS; Skolnick J; Jacob J -
Divergence of variant binding/neutralizing antibodies following SARS-CoV-2 booster vaccines in myeloma: Impact of hybrid immunity.
bioRxiv
08/22/2023 Authors: Moreno A; Manning K; Azeem MI; Nooka AK; Ellis M; Manalo RJ; Switchenko JM; Wali B; Kaufman JL; Hofmeister CC -
Treatment with sofosbuvir attenuates the adverse neurodevelopmental consequences of Zika virus infection in infant rhesus macaques.
J Neuroimmunol Volume: 381 Page(s): 578148
08/15/2023 Authors: Medina A; Rusnak R; Richardson R; Zimmerman MG; Suthar M; Schoof N; Kovacs-Balint Z; Mavigner M; Sanchez M; Chahroudi A -
COVID-19 booster vaccination during pregnancy enhances maternal binding and neutralizing antibody responses and transplacental antibody transfer to the newborn.
Vaccine Volume: 41 Page(s): 5296 - 5303
08/14/2023 Authors: Munoz FM; Posavad CM; Richardson BA; Badell ML; Bunge KE; Mulligan MJ; Parameswaran L; Kelly CW; Olson-Chen C; Novak RM -
Immunogenicity of NVX-CoV2373 heterologous boost against SARS-CoV-2 variants.
NPJ Vaccines Volume: 8 Page(s): 98
07/11/2023 Authors: Lyke KE; Atmar RL; Dominguez Islas C; Posavad CM; Deming ME; Branche AR; Johnston C; El Sahly HM; Edupuganti S; Mulligan MJ -
Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
Structure Volume: 31 Page(s): 801 - 811.e5
07/06/2023 Authors: Patel A; Kumar S; Lai L; Chakravarthy C; Valanparambil R; Reddy ES; Gottimukkala K; Bajpai P; Raju DR; Edara VV -
Low neutralizing activity of AZD7442 against current SARS-CoV-2 Omicron variants in patients with B-cell malignancies.
Blood Adv Volume: 7 Page(s): 2459 - 2462
06/13/2023 Authors: Chang A; Koff JL; Lai L; Orellana-Noia VM; Surati M; Leal AMK; Ellis ML; Wali B; Moreno A; Linderman SL -
Addendum: Systems vaccinology of the BNT162b2 mRNA vaccine in humans.
Nature Volume: 618 Page(s): E18
06/01/2023 Authors: Arunachalam PS; Scott MKD; Hagan T; Li C; Feng Y; Wimmers F; Grigoryan L; Trisal M; Edara VV; Lai L -
Durability of immune responses to mRNA booster vaccination against COVID-19.
J Clin Invest Volume: 133
05/15/2023 Authors: Arunachalam PS; Lai L; Samaha H; Feng Y; Hu M; Hui HS-Y; Wali B; Ellis M; Davis-Gardner ME; Huerta C -
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.
Sci Transl Med Volume: 15 Page(s): eadg7404
05/10/2023 Authors: Feng Y; Yuan M; Powers JM; Hu M; Munt JE; Arunachalam PS; Leist SR; Bellusci L; Kim J; Sprouse KR -
Virology under the Microscope-a Call for Rational Discourse.
mSphere Volume: 8 Page(s): e0003423
04/20/2023 Authors: Goodrum F; Lowen AC; Lakdawala S; Alwine J; Casadevall A; Imperiale MJ; Atwood W; Avgousti D; Baines J; Banfield B -
Ad26.COV2.S and SARS-CoV-2 spike protein ferritin nanoparticle vaccine protect against SARS-CoV-2 Omicron BA.5 challenge in macaques.
Cell Rep Med Volume: 4 Page(s): 101018
04/18/2023 Authors: Yu J; Thomas PV; Sciacca M; Wu C; Liu J; He X; Miller J; Hachmann NP; Surve N; McMahan K -
Infants and young children generate more durable antibody responses to SARS-CoV-2 infection than adults.
medRxiv
04/11/2023 Authors: Joshi D; Nyhoff LE; Zarnitsyna VI; Moreno A; Manning K; Linderman S; Burrell AR; Stephens K; Norwood C; Mantus G -
Interferon-induced transmembrane protein 3 (IFITM3) limits lethality of SARS-CoV-2 in mice.
EMBO Rep Volume: 24 Page(s): e56660
04/05/2023 Authors: Kenney AD; Zani A; Kawahara J; Eddy AC; Wang X-L; Mahesh KC; Lu M; Thomas J; Kohlmeier JE; Suthar MS -
Impaired SARS-CoV-2 Variant Neutralization and CD8+ T-cell Responses Following 3 Doses of mRNA Vaccines in Myeloma: Correlation with Breakthrough Infections.
Blood Cancer Discov Volume: 4 Page(s): 106 - 117
03/01/2023 Authors: Azeem MI; Nooka AK; Shanmugasundaram U; Cheedarla N; Potdar S; Manalo RJ; Moreno A; Switchenko JM; Cheedarla S; Doxie DB -
Virology under the Microscope-a Call for Rational Discourse.
J Virol Volume: 97 Page(s): e0008923
02/28/2023 Authors: Goodrum F; Lowen AC; Lakdawala S; Alwine J; Casadevall A; Imperiale MJ; Atwood W; Avgousti D; Baines J; Banfield B -
Virology under the Microscope-a Call for Rational Discourse.
mBio Volume: 14 Page(s): e0018823
02/28/2023 Authors: Goodrum F; Lowen AC; Lakdawala S; Alwine J; Casadevall A; Imperiale MJ; Atwood W; Avgousti D; Baines J; Banfield B -
An inactivated NDV-HXP-S COVID-19 vaccine elicits a higher proportion of neutralizing antibodies in humans than mRNA vaccination.
Sci Transl Med Volume: 15 Page(s): eabo2847
02/15/2023 Authors: Carreo JM; Raskin A; Singh G; Tcheou J; Kawabata H; Gleason C; Srivastava K; Vigdorovich V; Dambrauskas N; Gupta SL -
Ablation of Adar1 in myeloid cells imprints a global antiviral state in the lung and heightens early immunity against SARS-CoV-2.
Cell Rep Volume: 42 Page(s): 112038
01/31/2023 Authors: Adamska JZ; Verma R; Gupta S; Hagan T; Wimmers F; Floyd K; Li Q; Valore EV; Wang Y; Trisal M -
Neutralization against BA.2.75.2, BQ.1.1, and XBB from mRNA Bivalent Booster.
N Engl J Med Volume: 388 Page(s): 183 - 185
01/12/2023 Authors: Davis-Gardner ME; Lai L; Wali B; Samaha H; Solis D; Lee M; Porter-Morrison A; Hentenaar IT; Yamamoto F; Godbole S -
Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design.
PLoS One Volume: 18 Page(s): e0286297
01/01/2023 Authors: Horwitz LI; Thaweethai T; Brosnahan SB; Cicek MS; Fitzgerald ML; Goldman JD; Hess R; Hodder SL; Jacoby VL; Jordan MR -
Durability of immune responses to the booster mRNA vaccination against COVID-19.
medRxiv
12/04/2022 Authors: Arunachalam PS; Lai L; Samaha H; Feng Y; Hu M; Hui HS-Y; Wali B; Ellis M; Huerta C; Bechnack K -
Antibody binding and neutralization of live SARS-CoV-2 variants including BA.4/5 following booster vaccination of patients with B-cell malignancies.
Cancer Res Commun Volume: 2 Page(s): 1684 - 1692
12/01/2022 Authors: Chang A; Akhtar A; Lai L; Orellana-Noia VM; Linderman SL; McCook-Veal AA; Switchenko JM; Saini M; Valanparambil RM; Blum KA -
Neutralizing antibody responses in patients hospitalized with SARS-CoV-2 Delta or Omicron infection.
J Clin Invest Volume: 132
12/01/2022 Authors: Linderman SL; Lai L; Bocangel Gamarra EL; Lau MS; Edupuganti S; Surie D; Tenforde MW; Chappell JD; Mohr NM; Gibbs KW -
Protection against SARS-CoV-2 Omicron BA.1 variant challenge in macaques by prime-boost vaccination with Ad26.COV2.S and SpFN.
Sci Adv Volume: 8 Page(s): eade4433
11/25/2022 Authors: Yu J; Thomas PV; McMahan K; Jacob-Dolan C; Liu J; He X; Hope D; Martinez EJ; Chen W-H; Sciacca M -
A multispecific antibody prevents immune escape and confers pan-SARS-CoV-2 neutralization.
bioRxiv
11/21/2022 Authors: Misasi J; Wei RR; Wang L; Pegu A; Wei C-J; Oloniniyi OK; Zhou T; Moliva JI; Zhao B; Choe M -
Antibody Response to COVID-19 mRNA Vaccine in Patients With Lung Cancer After Primary Immunization and Booster: Reactivity to the SARS-CoV-2 WT Virus and Omicron Variant.
J Clin Oncol Volume: 40 Page(s): 3808 - 3816
11/20/2022 Authors: Valanparambil RM; Carlisle J; Linderman SL; Akthar A; Millett RL; Lai L; Chang A; McCook-Veal AA; Switchenko J; Nasti TH -
mRNA bivalent booster enhances neutralization against BA.2.75.2 and BQ.1.1.
bioRxiv
11/01/2022 Authors: Davis-Gardner ME; Lai L; Wali B; Samaha H; Solis D; Lee M; Porter-Morrison A; Hentenaar IT; Yamamoto F; Godbole S -
Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
bioRxiv
10/24/2022 Authors: Patel A; Kumar S; Lai L; Chakravarthy C; Valanparambil R; Reddy ES; Gottimukkala K; Bajpai P; Raju DR; Edara VV -
Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody.
Sci Adv Volume: 8 Page(s): eadd2032
10/07/2022 Authors: Kumar S; Patel A; Lai L; Chakravarthy C; Valanparambil R; Reddy ES; Gottimukkala K; Davis-Gardner ME; Edara VV; Linderman S -
Antibody Responses Against SARS-CoV-2 Variants after Booster Vaccination in Patients With B Cell Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia
Volume: 22 Page(s): S281 - S282
10/01/2022 Authors: Chang A; Lai L; Akhtar A; Linderman S; Orellana-Noia V; Saini M; Valanparambil R; Blum K; Allen P; Lechowicz M -
CLL-515 Antibody Responses Against SARS-CoV-2 Variants after Booster Vaccination in Patients With B Cell Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia.
Clin Lymphoma Myeloma Leuk Volume: 22 Suppl 2 Page(s): S281 - S282
10/01/2022 Authors: Chang A; Lai L; Akhtar A; Linderman S; Orellana-Noia V; Saini M; Valanparambil R; Blum K; Allen P; Lechowicz M -
Loss of Pfizer (BNT162b2) Vaccine-Induced Antibody Responses against the SARS-CoV-2 Omicron Variant in Adolescents and Adults.
J Virol Volume: 96 Page(s): e0058222
09/14/2022 Authors: Gupta SL; Mantus G; Manning KE; Ellis M; Patel M; Ciric CR; Lu A; Turner JS; O'Halloran JA; Presti RM -
Humoral Responses Against SARS-CoV-2 and Variants of Concern After mRNA Vaccines in Patients With Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia.
J Clin Oncol Volume: 40 Page(s): 3020 - 3031
09/10/2022 Authors: Chang A; Akhtar A; Linderman SL; Lai L; Orellana-Noia VM; Valanparambil R; Ahmed H; Zarnitsyna VI; McCook-Veal AA; Switchenko JM -
Determinants of Neutralizing Antibody Response After SARS CoV-2 Vaccination in Patients With Myeloma.
J Clin Oncol Volume: 40 Page(s): 3057 - 3064
09/10/2022 Authors: Nooka AK; Shanmugasundaram U; Cheedarla N; Verkerke H; Edara VV; Valanparambil R; Kaufman JL; Hofmeister CC; Joseph NS; Lonial S -
Innate antiviral immunity: how prior exposures can guide future responses.
Trends Immunol Volume: 43 Page(s): 696 - 705
09/01/2022 Authors: Tomalka JA; Suthar MS; Diamond MS; Sekaly RP -
The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization.
mSphere Volume: 7 Page(s): e0019322
08/31/2022 Authors: Karger AB; Brien JD; Christen JM; Dhakal S; Kemp TJ; Klein SL; Pinto LA; Premkumar L; Roback JD; Binder RA -
Rapid Detection and Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Omicron Variant in a Returning Traveler.
Clin Infect Dis Volume: 75 Page(s): e350 - e353
08/24/2022 Authors: Sexton ME; Waggoner JJ; Carmola LR; Nguyen PV; Wang E; Khosravi D; Taz A; Arthur RA; Patel M; Edara VV -
Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine.
Sci Transl Med Volume: 14 Page(s): eabq4130
08/17/2022 Authors: Arunachalam PS; Feng Y; Ashraf U; Hu M; Walls AC; Edara VV; Zarnitsyna VI; Aye PP; Golden N; Miranda MC -
Rapid decline in vaccine-boosted neutralizing antibodies against SARS-CoV-2 Omicron variant.
Cell Rep Med Volume: 3 Page(s): 100679
07/19/2022 Authors: Lyke KE; Atmar RL; Islas CD; Posavad CM; Szydlo D; Paul Chourdhury R; Deming ME; Eaton A; Jackson LA; Branche AR -
Erratum for Vanderheiden et al., "CCR2 Signaling Restricts SARS-CoV-2 Infection".
mBio Volume: 13 Page(s): e0025922
06/28/2022 Authors: Vanderheiden A; Thomas J; Soung AL; Davis-Gardner ME; Floyd K; Jin F; Cowan DA; Pellegrini K; Creanga A; Pegu A -
A modified vaccinia Ankara vaccine expressing spike and nucleocapsid protects rhesus macaques against SARS-CoV-2 Delta infection.
Sci Immunol Volume: 7 Page(s): eabo0226
06/24/2022 Authors: Routhu NK; Gangadhara S; Lai L; Davis-Gardner ME; Floyd K; Shiferaw A; Bartsch YC; Fischinger S; Khoury G; Rahman SA -
Contrasting behavior between the three human monocyte subsets in dengue pathophysiology.
iScience Volume: 25 Page(s): 104384
06/17/2022 Authors: Maheshwari D; Saini K; Singh P; Singla M; Nayak K; Aggarwal C; Chawla YM; Bajpai P; Kaur M; Gunisetty S -
Influenza Virus-like Particle-Based Hybrid Vaccine Containing RBD Induces Immunity against Influenza and SARS-CoV-2 Viruses.
Vaccines (Basel) Volume: 10
06/14/2022 Authors: Bommireddy R; Stone S; Bhatnagar N; Kumari P; Munoz LE; Oh J; Kim K-H; Berry JTL; Jacobsen KM; Jaafar L -
COVID-19 booster vaccination during pregnancy enhances maternal binding and neutralizing antibody responses and transplacental antibody transfer to the newborn (DMID 21-0004).
medRxiv
06/13/2022 Authors: Munoz FM; Posavad CM; Richardson BA; Badell ML; Bunge K; Mulligan MJ; Parameswaran L; Kelly C; Olsen-Chen C; Novak RM -
Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies.
Open Forum Infect Dis Volume: 9 Page(s): ofac171
06/01/2022 Authors: Figueiredo JC; Hirsch FR; Kushi LH; Nembhard WN; Crawford JM; Mantis N; Finster L; Merin NM; Merchant A; Reckamp KL -
Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and immunothrombosis.
Proc Natl Acad Sci U S A Volume: 119 Page(s): e2202012119
05/24/2022 Authors: Eltobgy MM; Zani A; Kenney AD; Estfanous S; Kim E; Badr A; Carafice C; Daily K; Whitham O; Pietrzak M -
Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice.
NPJ Vaccines Volume: 7 Page(s): 55
05/23/2022 Authors: Grigoryan L; Lee A; Walls AC; Lai L; Franco B; Arunachalam PS; Feng Y; Luo W; Vanderheiden A; Floyd K -
Safety and Immunogenicity of a Third Dose of SARS-CoV-2 mRNA Vaccine - An Interim Analysis.
Res Sq
05/03/2022 Authors: Anderson E; Jackson L; Rouphael N; Widge A; Montefiori D; Doria-Rose N; Suthar M; Cohen K; O'Connell S; Makowski M -
Defining the risk of SARS-CoV-2 variants on immune protection.
Nature Volume: 605 Page(s): 640 - 652
05/01/2022 Authors: DeGrace MM; Ghedin E; Frieman MB; Krammer F; Grifoni A; Alisoltani A; Alter G; Amara RR; Baric RS; Barouch DH -
mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron.
Cell Volume: 185 Page(s): 1556 - 1571.e18
04/28/2022 Authors: Gagne M; Moliva JI; Foulds KE; Andrew SF; Flynn BJ; Werner AP; Wagner DA; Teng I-T; Lin BC; Moore C -
Vaccine protection against the SARS-CoV-2 Omicron variant in macaques.
Cell Volume: 185 Page(s): 1549 - 1555.e11
04/28/2022 Authors: Chandrashekar A; Yu J; McMahan K; Jacob-Dolan C; Liu J; He X; Hope D; Anioke T; Barrett J; Chung B -
Pre-existing SARS-CoV-2 immunity influences potency, breadth, and durability of the humoral response to SARS-CoV-2 vaccination.
Cell Rep Med Volume: 3 Page(s): 100603
04/19/2022 Authors: Mantus G; Nyhoff LE; Edara V-V; Zarnitsyna VI; Ciric CR; Flowers MW; Norwood C; Ellis M; Hussaini L; Manning KE -
Reduced pathogenicity of the SARS-CoV-2 omicron variant in hamsters.
Med Volume: 3 Page(s): 262 - 268.e4
04/08/2022 Authors: McMahan K; Giffin V; Tostanoski LH; Chung B; Siamatu M; Suthar MS; Halfmann P; Kawaoka Y; Piedra-Mora C; Jain N -
SARS-CoV-2 Omicron Variant Neutralization after mRNA-1273 Booster Vaccination.
N Engl J Med Volume: 386 Page(s): 1088 - 1091
03/17/2022 Authors: Pajon R; Doria-Rose NA; Shen X; Schmidt SD; O'Dell S; McDanal C; Feng W; Tong J; Eaton A; Maglinao M -
Homologous and Heterologous Covid-19 Booster Vaccinations.
N Engl J Med Volume: 386 Page(s): 1046 - 1057
03/17/2022 Authors: Atmar RL; Lyke KE; Deming ME; Jackson LA; Branche AR; El Sahly HM; Rostad CA; Martin JM; Johnston C; Rupp RE -
The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization.
medRxiv
03/14/2022 Authors: Karger AB; Brien JD; Christen JM; Dhakal S; Kemp TJ; Klein SL; Pinto LA; Premkumar L; Roback JD; Binder RA -
SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters.
Nature Volume: 603 Page(s): 687 - 692
03/01/2022 Authors: Halfmann PJ; Iida S; Iwatsuki-Horimoto K; Maemura T; Kiso M; Scheaffer SM; Darling TL; Joshi A; Loeber S; Singh G -
Fighting the SARS-CoV-2 pandemic requires a global approach to understanding the heterogeneity of vaccine responses.
Nat Immunol Volume: 23 Page(s): 360 - 370
03/01/2022 Authors: Tomalka JA; Suthar MS; Deeks SG; Sekaly RP -
Timing of exposure is critical in a highly sensitive model of SARS-CoV-2 transmission.
PLoS Pathog Volume: 18 Page(s): e1010181
03/01/2022 Authors: Ganti K; Ferreri LM; Lee C-Y; Bair CR; Delima GK; Holmes KE; Suthar MS; Lowen AC -
mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 omicron variant.
Cell Rep Med Volume: 3 Page(s): 100529
02/15/2022 Authors: Edara V-V; Manning KE; Ellis M; Lai L; Moore KM; Foster SL; Floyd K; Davis-Gardner ME; Mantus G; Nyhoff LE -
Vaccine Protection Against the SARS-CoV-2 Omicron Variant in Macaques.
bioRxiv
02/07/2022 Authors: Chandrashekar A; Yu J; McMahan K; Jacob-Dolan C; Liu J; He X; Hope D; Anioke T; Barrett J; Chung B -
Antibody response to SARS-CoV-2 mRNA vaccine in lung cancer patients: Reactivity to vaccine antigen and variants of concern.
medRxiv
01/23/2022 Authors: Valanparambil R; Carlisle J; Linderman S; Akthar A; Millett RL; Lai L; Chang A; McCook A; Switchenko J; Nasti T -
Durability of immune responses to the BNT162b2 mRNA vaccine.
Med Volume: 3 Page(s): 25 - 27
01/14/2022 Authors: Suthar MS; Arunachalam PS; Hu M; Reis N; Trisal M; Raeber O; Chinthrajah S; Davis-Gardner ME; Manning K; Mudvari P -
Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in rhesus macaques coincides with anamnestic antibody response in the lung.
Cell Volume: 185 Page(s): 113 - 130.e15
01/06/2022 Authors: Gagne M; Corbett KS; Flynn BJ; Foulds KE; Wagner DA; Andrew SF; Todd J-PM; Honeycutt CC; McCormick L; Nurmukhambetova ST -
The SARS-CoV-2 B.1.1.529 Omicron virus causes attenuated infection and disease in mice and hamsters.
Res Sq
12/29/2021 Authors: Diamond M; Halfmann P; Maemura T; Iwatsuki-Horimoto K; Iida S; Kiso M; Scheaffer S; Darling T; Joshi A; Loeber S -
mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 Omicron variant.
bioRxiv
12/22/2021 Authors: Edara V-V; Manning KE; Ellis M; Lai L; Moore KM; Foster SL; Floyd K; Davis-Gardner ME; Mantus G; Nyhoff LE -
CCR2 Signaling Restricts SARS-CoV-2 Infection.
mBio Volume: 12 Page(s): e0274921
12/21/2021 Authors: Vanderheiden A; Thomas J; Soung AL; Davis-Gardner ME; Floyd K; Jin F; Cowan DA; Pellegrini K; Shi P-Y; Grakoui A -
Booster of mRNA-1273 Strengthens SARS-CoV-2 Omicron Neutralization.
medRxiv
12/20/2021 Authors: Doria-Rose NA; Shen X; Schmidt SD; O'Dell S; McDanal C; Feng W; Tong J; Eaton A; Maglinao M; Tang H -
Protection against SARS-CoV-2 Beta variant in mRNA-1273 vaccine-boosted nonhuman primates.
Science Volume: 374 Page(s): 1343 - 1353
12/10/2021 Authors: Corbett KS; Gagne M; Wagner DA; O' Connell S; Narpala SR; Flebbe DR; Andrew SF; Davis RL; Flynn B; Johnston TS -
Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge.
PLoS Biol Volume: 19 Page(s): e3001284
11/01/2021 Authors: Muruato A; Vu MN; Johnson BA; Davis-Gardner ME; Vanderheiden A; Lokugamage K; Schindewolf C; Crocquet-Valdes PA; Langsjoen RM; Plante JA -
A SARS-CoV-2 spike ferritin nanoparticle vaccine protects hamsters against Alpha and Beta virus variant challenge.
NPJ Vaccines Volume: 6 Page(s): 129
10/28/2021 Authors: Wuertz KM; Barkei EK; Chen W-H; Martinez EJ; Lakhal-Naouar I; Jagodzinski LL; Paquin-Proulx D; Gromowski GD; Swafford I; Ganesh A -
Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in nonhuman primates is coincident with an anamnestic antibody response in the lower airway.
bioRxiv
10/24/2021 Authors: Gagne M; Corbett KS; Flynn BJ; Foulds KE; Wagner DA; Andrew SF; Todd J-PM; Honeycutt CC; McCormick L; Nurmukhambetova ST -
Heterologous SARS-CoV-2 Booster Vaccinations - Preliminary Report.
medRxiv
10/15/2021 Authors: Atmar RL; Lyke KE; Deming ME; Jackson LA; Branche AR; El Sahly HM; Rostad CA; Martin JM; Johnston C; Rupp RE -
SARS-CoV-2 and other coronaviruses bind to phosphorylated glycans from the human lung.
Virology Volume: 562 Page(s): 142 - 148
10/01/2021 Authors: Byrd-Leotis L; Lasanajak Y; Bowen T; Baker K; Song X; Suthar MS; Cummings RD; Steinhauer DA -
mRNA-1273 protects against SARS-CoV-2 beta infection in nonhuman primates.
Nat Immunol Volume: 22 Page(s): 1306 - 1315
10/01/2021 Authors: Corbett KS; Werner AP; Connell SO; Gagne M; Lai L; Moliva JI; Flynn B; Choi A; Koch M; Foulds KE -
Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates.
Science Volume: 373 Page(s): eabj0299
09/17/2021 Authors: Corbett KS; Nason MC; Flach B; Gagne M; O'Connell S; Johnston TS; Shah SN; Edara VV; Floyd K; Lai L -
Durability of mRNA-1273 vaccine-induced antibodies against SARS-CoV-2 variants.
Science Volume: 373 Page(s): 1372 - 1377
09/17/2021 Authors: Pegu A; O'Connell SE; Schmidt SD; O'Dell S; Talana CA; Lai L; Albert J; Anderson E; Bennett H; Corbett KS -
Longitudinal immune dynamics of mild COVID-19 define signatures of recovery and persistence.
bioRxiv
08/19/2021 Authors: Talla A; Vasaikar SV; Lemos MP; Moodie Z; Lee Pebworth M-P; Henderson KE; Cohen KW; Czartoski JL; Lai L; Suthar MS -
Protective antibodies elicited by SARS-CoV-2 spike protein vaccination are boosted in the lung after challenge in nonhuman primates.
Sci Transl Med Volume: 13
08/18/2021 Authors: Francica JR; Flynn BJ; Foulds KE; Noe AT; Werner AP; Moore IN; Gagne M; Johnston TS; Tucker C; Davis RL -
Infection and Vaccine-Induced Neutralizing-Antibody Responses to the SARS-CoV-2 B.1.617 Variants.
N Engl J Med Volume: 385 Page(s): 664 - 666
08/12/2021 Authors: Edara V-V; Pinsky BA; Suthar MS; Lai L; Davis-Gardner ME; Floyd K; Flowers MW; Wrammert J; Hussaini L; Ciric CR -
Protection against SARS-CoV-2 Beta Variant in mRNA-1273 Boosted Nonhuman Primates.
bioRxiv
08/12/2021 Authors: Corbett KS; Gagne M; Wagner DA; Connell SO; Narpala SR; Flebbe DR; Andrew SF; Davis RL; Flynn B; Johnston TS -
Systems vaccinology of the BNT162b2 mRNA vaccine in humans.
Nature Volume: 596 Page(s): 410 - 416
08/01/2021 Authors: Arunachalam PS; Scott MKD; Hagan T; Li C; Feng Y; Wimmers F; Grigoryan L; Trisal M; Edara VV; Lai L -
In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains.
Nature Volume: 596 Page(s): 103 - 108
08/01/2021 Authors: Chen RE; Winkler ES; Case JB; Aziati ID; Bricker TL; Joshi A; Darling TL; Ying B; Errico JM; Shrihari S -
Immune responses and therapeutic challenges in paediatric patients with new-onset acute myeloid leukaemia and concomitant COVID-19.
Br J Haematol Volume: 194 Page(s): 549 - 553
08/01/2021 Authors: Patel PA; Lapp SA; Grubbs G; Edara VV; Rostad CA; Stokes CL; Pauly MG; Anderson EJ; Piantadosi A; Suthar MS -
An intranasal vaccine durably protects against SARS-CoV-2 variants in mice.
Cell Rep Volume: 36 Page(s): 109452
07/27/2021 Authors: Hassan AO; Shrihari S; Gorman MJ; Ying B; Yuan D; Raju S; Chen RE; Dmitriev IP; Kashentseva E; Adams LJ -
Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and Tcells.
Cell Rep Med Volume: 2 Page(s): 100354
07/20/2021 Authors: Cohen KW; Linderman SL; Moodie Z; Czartoski J; Lai L; Mantus G; Norwood C; Nyhoff LE; Edara VV; Floyd K -
A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates.
Sci Immunol Volume: 6
07/15/2021 Authors: Pino M; Abid T; Pereira Ribeiro S; Edara VV; Floyd K; Smith JC; Latif MB; Pacheco-Sanchez G; Dutta D; Wang S -
Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects.
Cell Rep Volume: 36 Page(s): 109353
07/13/2021 Authors: Jennewein MF; MacCamy AJ; Akins NR; Feng J; Homad LJ; Hurlburt NK; Seydoux E; Wan Y-H; Stuart AB; Edara VV -
Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells.
medRxiv
06/18/2021 Authors: Cohen KW; Linderman SL; Moodie Z; Czartoski J; Lai L; Mantus G; Norwood C; Nyhoff LE; Edara VV; Floyd K -
A SARS-CoV-2 spike ferritin nanoparticle vaccine protects against heterologous challenge with B.1.1.7 and B.1.351 virus variants in Syrian golden hamsters.
bioRxiv
06/16/2021 Authors: Wuertz KM; Barkei EK; Chen W-H; Martinez EJ; Lakhal-Naouar I; Jagodzinski LL; Paquin-Proulx D; Gromowski GD; Swafford I; Ganesh A -
SARS-CoV-2 RBD trimer protein adjuvanted with Alum-3M-052 protects from SARS-CoV-2 infection and immune pathology in the lung.
Nat Commun Volume: 12 Page(s): 3587
06/11/2021 Authors: Routhu NK; Cheedarla N; Bollimpelli VS; Gangadhara S; Edara VV; Lai L; Sahoo A; Shiferaw A; Styles TM; Floyd K -
Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19.
N Engl J Med Volume: 384 Page(s): 2259 - 2261
06/10/2021 Authors: Doria-Rose N; Suthar MS; Makowski M; O'Connell S; McDermott AB; Flach B; Ledgerwood JE; Mascola JR; Graham BS; Lin BC -
Characterization of neutralizing versus binding antibodies and memory B cells in COVID-19 recovered individuals from India.
Virology Volume: 558 Page(s): 13 - 21
06/01/2021 Authors: Nayak K; Gottimukkala K; Kumar S; Reddy ES; Edara VV; Kauffman R; Floyd K; Mantus G; Savargaonkar D; Goel PK -
Adjuvanting a subunit COVID-19 vaccine to induce protective immunity.
Nature Volume: 594 Page(s): 253 - 258
06/01/2021 Authors: Arunachalam PS; Walls AC; Golden N; Atyeo C; Fischinger S; Li C; Aye P; Navarro MJ; Lai L; Edara VV -
Evaluation of Cellular and Serological Responses to Acute SARS-CoV-2 Infection Demonstrates the Functional Importance of the Receptor-Binding Domain.
J Immunol Volume: 206 Page(s): 2605 - 2613
06/01/2021 Authors: Mantus G; Nyhoff LE; Kauffman RC; Edara VV; Lai L; Floyd K; Shi P-Y; Menachery VD; Edupuganti S; Scherer EM -
Evaluation of mRNA-1273 against SARS-CoV-2 B.1.351 Infection in Nonhuman Primates.
bioRxiv
05/24/2021 Authors: Corbett KS; Werner AP; O' Connell S; Gagne M; Lai L; Moliva JI; Flynn B; Choi A; Koch M; Foulds KE -
Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants.
bioRxiv
05/16/2021 Authors: Pegu A; O'Connell S; Schmidt SD; O'Dell S; Talana CA; Lai L; Albert J; Anderson E; Bennett H; Corbett KS -
Plasmacytoid dendritic cells produce type I interferon and reduce viral replication in airway epithelial cells after SARS-CoV-2 infection.
bioRxiv
05/13/2021 Authors: Cervantes-Barragan L; Vanderheiden A; Royer CJ; Davis-Gardner ME; Ralfs P; Chirkova T; Anderson LJ; Grakoui A; Suthar MS -
Neutralizing Antibodies Against SARS-CoV-2 Variants After Infection and Vaccination.
JAMA Volume: 325 Page(s): 1896 - 1898
05/11/2021 Authors: Edara VV; Hudson WH; Xie X; Ahmed R; Suthar MS -
Infection and vaccine-induced neutralizing antibody responses to the SARS-CoV-2 B.1.617.1 variant.
bioRxiv
05/10/2021 Authors: Edara V-V; Lai L; Sahoo MK; Floyd K; Sibai M; Solis D; Flowers MW; Hussaini L; Ciric CR; Bechnack S -
CCR2-dependent monocyte-derived cells restrict SARS-CoV-2 infection.
bioRxiv
05/04/2021 Authors: Vanderheiden A; Thomas J; Soung AL; Davis-Gardner ME; Floyd K; Jin F; Cowan DA; Pellegrini K; Creanga A; Pegu A -
Mouse Adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge.
bioRxiv
05/04/2021 Authors: Muruato A; Vu MN; Johnson BA; Davis-Gardner ME; Vanderheiden A; Lokugmage K; Schindewolf C; Crocquet-Valdes PA; Langsjoen RM; Plante JA -
Intrinsic antibody mediated enhancement of ZIKV infection in placental macrophages
Volume: 206
05/01/2021 Authors: Moore K; Zimmerman MG; Kauffman RC; Wrammert J; Suthar MS -
Diminished monocyte response in severe COVID-19 patients
Volume: 206
05/01/2021 Authors: Davis-Gardner ME; Edara V; Lai L; Jin F; Floyd K; Nyhoff L; Mantus G; Adelman M; Pellegrini K; Chirkova T -
Cell-intrinsic MAVS promotes antigen specific CD8+T cell proliferation and mitochondrial metabolism
Volume: 206
05/01/2021 Authors: Vanderheiden A; Valenzuela RA; Verkerke H; Jin F; Price M; Boss JM; Grakoui A; Suthar MS -
Immune Correlates of Protection by mRNA-1273 Immunization against SARS-CoV-2 Infection in Nonhuman Primates.
bioRxiv
04/23/2021 Authors: Corbett KS; Nason MC; Flach B; Gagne M; O' Connell S; Johnston TS; Shah SN; Edara VV; Floyd K; Lai L -
Infection- and vaccine-induced antibody binding and neutralization of the B.1.351 SARS-CoV-2 variant.
Cell Host Microbe Volume: 29 Page(s): 516 - 521.e3
04/14/2021 Authors: Edara VV; Norwood C; Floyd K; Lai L; Davis-Gardner ME; Hudson WH; Mantus G; Nyhoff LE; Adelman MW; Fineman R -
Prevalence of SARS-CoV-2 antibodies in pediatric healthcare workers.
Int J Infect Dis Volume: 105 Page(s): 474 - 481
04/01/2021 Authors: Morris CR; Sullivan P; Mantus G; Sanchez T; Zlotorzynska M; Hanberry B; Iyer S; Heilman S; Camacho-Gonzalez A; Figueroa J -
Isolation and Characterization of Cross-Neutralizing Coronavirus Antibodies from COVID-19+ Subjects.
bioRxiv
03/24/2021 Authors: Jennewein MF; MacCamy AJ; Akins NR; Feng J; Homad LJ; Hurlburt NK; Seydoux E; Wan Y-H; Stuart AB; Edara VV -
A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs.
Immunity Volume: 54 Page(s): 542 - 556.e9
03/09/2021 Authors: Routhu NK; Cheedarla N; Gangadhara S; Bollimpelli VS; Boddapati AK; Shiferaw A; Rahman SA; Sahoo A; Edara VV; Lai L -
Vaccination with SARS-CoV-2 Spike Protein and AS03 Adjuvant Induces Rapid Anamnestic Antibodies in the Lung and Protects Against Virus Challenge in Nonhuman Primates.
bioRxiv
03/02/2021 Authors: Francica JR; Flynn BJ; Foulds KE; Noe AT; Werner AP; Moore IN; Gagne M; Johnston TS; Tucker C; Davis RL -
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis.
Nature Volume: 591 Page(s): 293 - 299
03/01/2021 Authors: Johnson BA; Xie X; Bailey AL; Kalveram B; Lokugamage KG; Muruato A; Zou J; Zhang X; Juelich T; Smith JK -
Reduced binding and neutralization of infection- and vaccine-induced antibodies to the B.1.351 (South African) SARS-CoV-2 variant.
bioRxiv
02/22/2021 Authors: Edara VV; Norwood C; Floyd K; Lai L; Davis-Gardner ME; Hudson WH; Mantus G; Nyhoff LE; Adelman MW; Fineman R -
Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates.
bioRxiv
02/11/2021 Authors: S Arunachalam P; Walls AC; Golden N; Atyeo C; Fischinger S; Li C; Aye P; Navarro MJ; Lai L; Edara VV -
TLR7 and RIG-I dual-adjuvant loaded nanoparticles drive broadened and synergistic responses in dendritic cells in vitro and generate unique cellular immune responses in influenza vaccination.
J Control Release Volume: 330 Page(s): 866 - 877
02/10/2021 Authors: Toy R; Keenum MC; Pradhan P; Phang K; Chen P; Chukwu C; Nguyen LAH; Liu J; Jain S; Kozlowski G -
Infection and mRNA-1273 vaccine antibodies neutralize SARS-CoV-2 UK variant.
medRxiv
02/05/2021 Authors: Edara VV; Floyd K; Lai L; Gardner M; Hudson W; Piantadosi A; Waggoner JJ; Babiker A; Ahmed R; Xie X -
Comprehensive analysis of COVID-19 during pregnancy.
Biochem Biophys Res Commun Volume: 538 Page(s): 180 - 186
01/29/2021 Authors: Moore KM; Suthar MS -
The amphibian peptide Yodha is virucidal for Zika and dengue viruses.
Sci Rep Volume: 11 Page(s): 602
01/12/2021 Authors: Lee SH; Kim EH; O'neal JT; Dale G; Holthausen DJ; Bowen JR; Quicke KM; Skountzou I; Gopal S; George S -
Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination.
N Engl J Med Volume: 384 Page(s): 80 - 82
01/07/2021 Authors: Widge AT; Rouphael NG; Jackson LA; Anderson EJ; Roberts PC; Makhene M; Chappell JD; Denison MR; Stevens LJ; Pruijssers AJ -
Original antigenic sin responses to Betacoronavirus spike proteins are observed in a mouse model, but are not apparent in children following SARS-CoV-2 infection.
PLoS One Volume: 16 Page(s): e0256482
01/01/2021 Authors: Lapp SA; Edara VV; Lu A; Lai L; Hussaini L; Chahroudi A; Anderson LJ; Suthar MS; Anderson EJ; Rostad CA -
Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults.
N Engl J Med Volume: 383 Page(s): 2427 - 2438
12/17/2020 Authors: Anderson EJ; Rouphael NG; Widge AT; Jackson LA; Roberts PC; Makhene M; Chappell JD; Denison MR; Stevens LJ; Pruijssers AJ -
Development of a Rapid Focus Reduction Neutralization Test Assay for Measuring SARS-CoV-2 Neutralizing Antibodies.
Curr Protoc Immunol Volume: 131 Page(s): e116
12/01/2020 Authors: Vanderheiden A; Edara VV; Floyd K; Kauffman RC; Mantus G; Anderson E; Rouphael N; Edupuganti S; Shi P-Y; Menachery VD -
Quantitative SARS-CoV-2 Serology in Children With Multisystem Inflammatory Syndrome (MIS-C).
Pediatrics Volume: 146
12/01/2020 Authors: Rostad CA; Chahroudi A; Mantus G; Lapp SA; Teherani M; Macoy L; Tarquinio KM; Basu RK; Kao C; Linam WM -
SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity.
Nat Commun Volume: 11 Page(s): 6013
11/26/2020 Authors: Zhang L; Jackson CB; Mou H; Ojha A; Peng H; Quinlan BD; Rangarajan ES; Pan A; Vanderheiden A; Suthar MS -
Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation.
Nat Commun Volume: 11 Page(s): 5413
10/27/2020 Authors: Hurlburt NK; Seydoux E; Wan Y-H; Edara VV; Stuart AB; Feng J; Suthar MS; McGuire AT; Stamatatos L; Pancera M -
Prevalence of SARS-CoV-2 Antibodies in Pediatric Health Care Workers in Atlanta, Georgia
Volume: 76 Page(s): S124 - S125
10/01/2020 Authors: Morris CR; Camacho-Gonzalez A; Chen C; Heilman S; Iyer S; Mantus G; Sanchez T; Sullivan P; Suthar M; Wrammert J -
COVID-19 convalescent plasma clears SARS-CoV-2 refractory to remdesivir in an infant with congenital heart disease.
Blood Adv Volume: 4 Page(s): 4278 - 4281
09/22/2020 Authors: Rodriguez Z; Shane AL; Verkerke H; Lough C; Zimmerman MG; Suthar M; Wrammert J; MacDonald H; Wolf M; Clarke S -
Type I and Type III Interferons Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures.
J Virol Volume: 94
09/15/2020 Authors: Vanderheiden A; Ralfs P; Chirkova T; Upadhyay AA; Zimmerman MG; Bedoya S; Aoued H; Tharp GM; Pellegrini KL; Manfredi C -
Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis.
bioRxiv
08/26/2020 Authors: Johnson BA; Xie X; Kalveram B; Lokugamage KG; Muruato A; Zou J; Zhang X; Juelich T; Smith JK; Zhang L -
Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients.
Cell Rep Med Volume: 1 Page(s): 100040
06/23/2020 Authors: Suthar MS; Zimmerman MG; Kauffman RC; Mantus G; Linderman SL; Hudson WH; Vanderheiden A; Nyhoff L; Davis CW; Adekunle O -
Long-term alterations in brain and behavior after postnatal Zika virus infection in infant macaques.
Nat Commun Volume: 11 Page(s): 2534
05/21/2020 Authors: Raper J; Kovacs-Balint Z; Mavigner M; Gumber S; Burke MW; Habib J; Mattingly C; Fair D; Earl E; Feczko E -
Rapid generation of neutralizing antibody responses in COVID-19 patients.
medRxiv
05/08/2020 Authors: Suthar MS; Zimmerman M; Kauffman R; Mantus G; Linderman S; Vanderheiden A; Nyhoff L; Davis C; Adekunle S; Affer M -
CD8+T cell intrinsic MAVS promotes antigen-specific responses and mitochondrial metabolism during West Nile Virus neuroinvasive disease
Volume: 204
05/01/2020 Authors: Vanderheiden A; Aguilar-Valenzuela R; Verkerke H; Price M; Boss JM; Grakoui A; Suthar MS -
Cross-reactive dengue immune complexes modulate innate antiviral responses to Zika virus infection in human placental macrophages
Volume: 204
05/01/2020 Authors: Zimmerman MG; Eddins D; Muhammad A; Register E; Kauffman R; Cordes S; Jean V; Haddad L; Wrammert J; Suthar MS -
Cross-Reactive Antibodies during Zika Virus Infection: Protection, Pathogenesis, and Placental Seeding.
Cell Host Microbe Volume: 27 Page(s): 14 - 24
01/08/2020 Authors: Zimmerman MG; Wrammert J; Suthar MS -
STAT5: a Target of Antagonism by Neurotropic Flaviviruses.
J Virol Volume: 93
12/01/2019 Authors: Zimmerman MG; Bowen JR; McDonald CE; Young E; Baric RS; Pulendran B; Suthar MS -
West Nile Virus Infection Blocks Inflammatory Response and T Cell Costimulatory Capacity of Human Monocyte-Derived Dendritic Cells.
J Virol Volume: 93
12/01/2019 Authors: Zimmerman MG; Bowen JR; McDonald CE; Pulendran B; Suthar MS -
Strong TH1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy.
Sci Transl Med Volume: 11
11/20/2019 Authors: Chamcha V; Reddy PBJ; Kannanganat S; Wilkins C; Gangadhara S; Velu V; Green R; Law GL; Chang J; Bowen JR -
RNA Helicase LGP2 Negatively Regulates RIG-I Signaling by Preventing TRIM25-Mediated Caspase Activation and Recruitment Domain Ubiquitination.
J Interferon Cytokine Res Volume: 39 Page(s): 669 - 683
11/01/2019 Authors: Quicke KM; Kim KY; Horvath CM; Suthar MS -
Acetaminophen Intoxication Rapidly Induces Apoptosis of Intestinal Crypt Stem Cells and Enhances Intestinal Permeability.
Hepatol Commun Volume: 3 Page(s): 1435 - 1449
11/01/2019 Authors: Chopyk DM; Stuart JD; Zimmerman MG; Wen J; Gumber S; Suthar MS; Thapa M; Czaja MJ; Grakoui A -
The Effect of Anticoagulants, Temperature, and Time on the Human Plasma Metabolome and Lipidome from Healthy Donors as Determined by Liquid Chromatography-Mass Spectrometry.
Biomolecules Volume: 9
05/23/2019 Authors: Khadka M; Todor A; Maner-Smith KM; Colucci JK; Tran V; Gaul DA; Anderson EJ; Natrajan MS; Rouphael N; Mulligan MJ -
West Nile Virus-Inclusive Single-Cell RNA Sequencing Reveals Heterogeneity in the Type I Interferon Response within Single Cells.
J Virol Volume: 93
03/15/2019 Authors: O'Neal JT; Upadhyay AA; Wolabaugh A; Patel NB; Bosinger SE; Suthar MS -
Cell-type specificity and functional redundancy of RIG-I-like receptors in innate immune sensing of Coxsackievirus B3 and encephalomyocarditis virus.
Virology Volume: 528 Page(s): 7 - 18
02/01/2019 Authors: Francisco E; Suthar M; Gale M; Rosenfeld AB; Racaniello VR -
Dendritic cell-associated MAVS is required to control West Nile virus replication and ensuing humoral immune responses.
PLoS One Volume: 14 Page(s): e0218928
01/01/2019 Authors: Roe K; Giordano D; Young LB; Draves KE; Holder U; Suthar MS; Gale M; Clark EA -
Pre-Existing Dengue Immunity Drives a DENV-Biased Plasmablast Response in ZIKV-Infected Patient.
Viruses Volume: 11
12/29/2018 Authors: Bhaumik SK; Priyamvada L; Kauffman RC; Lai L; Natrajan MS; Cho A; Rouphael N; Suthar MS; Mulligan MJ; Wrammert J -
Cross-Reactive Dengue Virus Antibodies Augment Zika Virus Infection of Human Placental Macrophages.
Cell Host Microbe Volume: 24 Page(s): 731 - 742.e6
11/14/2018 Authors: Zimmerman MG; Quicke KM; O'Neal JT; Arora N; Machiah D; Priyamvada L; Kauffman RC; Register E; Adekunle O; Swieboda D -
Taking the defensive: Immune control of Zika virus infection.
Virus Res Volume: 254 Page(s): 21 - 26
08/02/2018 Authors: Bowen JR; Zimmerman MG; Suthar MS -
Dynamics of Tissue-Specific CD8+ T Cell Responses during West Nile Virus Infection.
J Virol Volume: 92
05/15/2018 Authors: Aguilar-Valenzuela R; Netland J; Seo Y-J; Bevan MJ; Grakoui A; Suthar MS -
Postnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques.
Sci Transl Med Volume: 10
04/04/2018 Authors: Mavigner M; Raper J; Kovacs-Balint Z; Gumber S; O'Neal JT; Bhaumik SK; Zhang X; Habib J; Mattingly C; McDonald CE -
Editorial overview: Viral immunology: Generating immunity to diverse viral pathogens.
Curr Opin Virol Volume: 28 Page(s): viii - x
02/01/2018 Authors: Hickman HD; Suthar MS -
Humoral Immune Responses Against Zika Virus Infection and the Importance of Preexisting Flavivirus Immunity.
J Infect Dis Volume: 216 Page(s): S906 - S911
12/16/2017 Authors: Priyamvada L; Suthar MS; Ahmed R; Wrammert J -
Transgenic West Nile Virus virus-specific CDS+ T cells provide insights on activation patterns and protective role of cytotoxic T cells during infection
Volume: 198
05/01/2017 Authors: Aguilar-Valenzuela R; Seo Y-J; Grakoui A; Suthar MS -
West Nile virus antagonism of a RIG-I, type I interferon, and STAT5 signaling axis in human dendritic cells
Volume: 198
05/01/2017 Authors: Bowen JR; McDonald CE; Suthar MS -
Negative regulators of the RIG-I-like receptor signaling pathway.
Eur J Immunol Volume: 47 Page(s): 615 - 628
04/01/2017 Authors: Quicke KM; Diamond MS; Suthar MS -
Zika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic Cells.
PLoS Pathog Volume: 13 Page(s): e1006164
02/01/2017 Authors: Bowen JR; Quicke KM; Maddur MS; O'Neal JT; McDonald CE; Fedorova NB; Puri V; Shabman RS; Pulendran B; Suthar MS -
Jak Inhibitors Modulate Production of Replication-Competent Zika Virus in Human Hofbauer, Trophoblasts, and Neuroblastoma cells.
Pathog Immun Volume: 2 Page(s): 199 - 218
01/01/2017 Authors: Gavegnano C; Bassit LC; Cox BD; Hsiao H-M; Johnson EL; Suthar M; Chakraborty R; Schinazi RF -
Local Cellular and Cytokine Cues in the Spleen Regulate In Situ T Cell Receptor Affinity, Function, and Fate of CD8+ T Cells.
Immunity Volume: 45 Page(s): 988 - 998
11/15/2016 Authors: Seo Y-J; Jothikumar P; Suthar MS; Zhu C; Grakoui A -
N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection.
Cell Host Microbe Volume: 20 Page(s): 654 - 665
11/09/2016 Authors: Gokhale NS; McIntyre ABR; McFadden MJ; Roder AE; Kennedy EM; Gandara JA; Hopcraft SE; Quicke KM; Vazquez C; Willer J -
Prolonged activation of innate antiviral gene signature after childbirth is determined by IFNL3 genotype.
Proc Natl Acad Sci U S A Volume: 113 Page(s): 10678 - 10683
09/20/2016 Authors: Price AA; Tedesco D; Prasad MR; Workowski KA; Walker CM; Suthar MS; Honegger JR; Grakoui A -
Zika Virus Infects Human Placental Macrophages.
Cell Host Microbe Volume: 20 Page(s): 83 - 90
07/13/2016 Authors: Quicke KM; Bowen JR; Johnson EL; McDonald CE; Ma H; O'Neal JT; Rajakumar A; Wrammert J; Rimawi BH; Pulendran B -
Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus.
Proc Natl Acad Sci U S A Volume: 113 Page(s): 7852 - 7857
07/12/2016 Authors: Priyamvada L; Quicke KM; Hudson WH; Onlamoon N; Sewatanon J; Edupuganti S; Pattanapanyasat K; Chokephaibulkit K; Mulligan MJ; Wilson PC -
A complement-microglial axis drives synapse loss during virus-induced memory impairment.
Nature Volume: 534 Page(s): 538 - 543
06/23/2016 Authors: Vasek MJ; Garber C; Dorsey D; Durrant DM; Bollman B; Soung A; Yu J; Perez-Torres C; Frouin A; Wilton DK -
Systems biology: A tool for charting the antiviral landscape.
Virus Res Volume: 218 Page(s): 2 - 9
06/15/2016 Authors: Bowen JR; Ferris MT; Suthar MS -
The role of the RIG-I like receptors in mediating CD8+T cell immunity during virus infection
Volume: 196
05/01/2016 Authors: Aguilar-Valenzuela RA; Ma DY; Suthar MS -
Mechanisms of LGP2-dependent regulation of RIG-I signaling and dendritic cell activation
Volume: 196
05/01/2016 Authors: Quicke K; Suthar MS -
A systems biology approach unravels the host response to West Nile virus infection in human dendritic cells
Volume: 196
05/01/2016 Authors: Bowen JR; Suthar MS -
Ly6C(hi) monocytes control acute Ross River virus infection through an IRF7-dependent mechanism that can be counteracted by determinants in nsP1
Volume: 196
05/01/2016 Authors: Haist KC; Burrack KS; Diamond MS; Suthar MS; Morrison TE -
S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3.
Nat Immunol Volume: 17 Page(s): 514 - 522
05/01/2016 Authors: Wang F; Alain T; Szretter KJ; Stephenson K; Pol JG; Atherton MJ; Hoang H-D; Fonseca BD; Zakaria C; Chen L -
Mechanisms of innate immune evasion in re-emerging RNA viruses.
Curr Opin Virol Volume: 12 Page(s): 26 - 37
06/01/2015 Authors: Ma DY; Suthar MS -
Liver fibrosis occurs through dysregulation of MyD88-dependent innate B-cell activity.
Hepatology Volume: 61 Page(s): 2067 - 2079
06/01/2015 Authors: Thapa M; Chinnadurai R; Velazquez VM; Tedesco D; Elrod E; Han J-H; Sharma P; Ibegbu C; Gewirtz A; Anania F -
Genetic diversity in the collaborative cross model recapitulates human West Nile virus disease outcomes.
mBio Volume: 6 Page(s): e00493 - e00415
05/05/2015 Authors: Graham JB; Thomas S; Swarts J; McMillan AA; Ferris MT; Suthar MS; Treuting PM; Ireton R; Gale M; Lund JM -
Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development.
Hepatology Volume: 61 Page(s): 843 - 856
03/01/2015 Authors: Velazquez VM; Uebelhoer LS; Thapa M; Ibegbu CC; Courtney C; Bosinger SE; Magliocca JF; Adams AB; Kirk AD; Knechtle SJ -
Systems analysis of West Nile virus infection.
Curr Opin Virol Volume: 6 Page(s): 70 - 75
06/01/2014 Authors: Suthar MS; Pulendran B -
Deficient IFN signaling by myeloid cells leads to MAVS-dependent virus-induced sepsis.
PLoS Pathog Volume: 10 Page(s): e1004086
04/01/2014 Authors: Pinto AK; Ramos HJ; Wu X; Aggarwal S; Shrestha B; Gorman M; Kim KY; Suthar MS; Atkinson JP; Gale M -
The essential, nonredundant roles of RIG-I and MDA5 in detecting and controlling West Nile virus infection.
J Virol Volume: 87 Page(s): 11416 - 11425
11/01/2013 Authors: Errett JS; Suthar MS; McMillan A; Diamond MS; Gale M -
Pattern recognition receptor MDA5 modulates CD8+ T cell-dependent clearance of West Nile virus from the central nervous system.
J Virol Volume: 87 Page(s): 11401 - 11415
11/01/2013 Authors: Lazear HM; Pinto AK; Ramos HJ; Vick SC; Shrestha B; Suthar MS; Gale M; Diamond MS -
The innate immune playbook for restricting West Nile virus infection.
Viruses Volume: 5 Page(s): 2643 - 2658
10/30/2013 Authors: Quicke KM; Suthar MS -
Innate immune sensing of flaviviruses.
PLoS Pathog Volume: 9 Page(s): e1003541
09/01/2013 Authors: Suthar MS; Aguirre S; Fernandez-Sesma A -
RIG-I receptor regulation of T cell immunity during virus infection
Volume: 190
05/01/2013 Authors: Suthar M; Ramos H; Brassil M; Netland J; Chappell C; Blahnik G; McMillan A; Diamond M; Clark E; Bevan M -
IKK epsilon is targeted by pathogenic West Nile virus to evade host immune control
Volume: 190
05/01/2013 Authors: Huang A; Perwitasari O; Ramos H; Suthar M; Brassil M; Blahnik G; Gale M -
CD22 is required for protection against West Nile virus Infection.
J Virol Volume: 87 Page(s): 3361 - 3375
03/01/2013 Authors: Ma DY; Suthar MS; Kasahara S; Gale M; Clark EA -
West Nile virus infection and immunity.
Nat Rev Microbiol Volume: 11 Page(s): 115 - 128
02/01/2013 Authors: Suthar MS; Diamond MS; Gale M -
A systems biology approach reveals that tissue tropism to West Nile virus is regulated by antiviral genes and innate immune cellular processes.
PLoS Pathog Volume: 9 Page(s): e1003168
02/01/2013 Authors: Suthar MS; Brassil MM; Blahnik G; McMillan A; Ramos HJ; Proll SC; Belisle SE; Katze MG; Gale M -
IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling.
PLoS Pathog Volume: 9 Page(s): e1003118
01/01/2013 Authors: Lazear HM; Lancaster A; Wilkins C; Suthar MS; Huang A; Vick SC; Clepper L; Thackray L; Brassil MM; Virgin HW -
The RIG-I-like receptor LGP2 controls CD8(+) T cell survival and fitness.
Immunity Volume: 37 Page(s): 235 - 248
08/24/2012 Authors: Suthar MS; Ramos HJ; Brassil MM; Netland J; Chappell CP; Blahnik G; McMillan A; Diamond MS; Clark EA; Bevan MJ -
Infectious clones of novel lineage 1 and lineage 2 West Nile virus strains WNV-TX02 and WNV-Madagascar.
J Virol Volume: 86 Page(s): 7704 - 7709
07/01/2012 Authors: Suthar MS; Brassil MM; Blahnik G; Gale M -
IL-1 signaling promotes CNS-intrinsic immune control of West Nile virus infection.
PLoS Pathog Volume: 8 Page(s): e1003039
01/01/2012 Authors: Ramos HJ; Lanteri MC; Blahnik G; Negash A; Suthar MS; Brassil MM; Sodhi K; Treuting PM; Busch MP; Norris PJ -
IL-1 signaling and the NLRP3 Inflammasome are required for CNS-specific protective immunity against West Nile Virus
Volume: 56 Page(s): 11 - 11
10/01/2011 Authors: Ramos HJ; Suthar M; Negash A; Blahnick G; Brassil M; Gale M -
A Systems Biology approach to defining the host immune response to West Nile virus infection
Volume: 56 Page(s): 48 - 49
10/01/2011 Authors: Suthar MS; Brassil M; Proll S; Belisle S; Katze MG; Gale M -
Interferon regulatory factor-1 (IRF-1) shapes both innate and CD8(+) T cell immune responses against West Nile virus infection.
PLoS Pathog Volume: 7 Page(s): e1002230
09/01/2011 Authors: Brien JD; Daffis S; Lazear HM; Cho H; Suthar MS; Gale M; Diamond MS -
Nitric oxide controls an inflammatory-like Ly6C(hi)PDCA1+ DC subset that regulates Th1 immune responses.
J Leukoc Biol Volume: 89 Page(s): 443 - 455
03/01/2011 Authors: Giordano D; Li C; Suthar MS; Draves KE; Ma DY; Gale M; Clark EA -
The innate immune adaptor molecule MyD88 restricts West Nile virus replication and spread in neurons of the central nervous system.
J Virol Volume: 84 Page(s): 12125 - 12138
12/01/2010 Authors: Szretter KJ; Daffis S; Patel J; Suthar MS; Klein RS; Gale M; Diamond MS -
Rabies virus infection induces type I interferon production in an IPS-1 dependent manner while dendritic cell activation relies on IFNAR signaling.
PLoS Pathog Volume: 6 Page(s): e1001016
07/22/2010 Authors: Faul EJ; Wanjalla CN; Suthar MS; Gale M; Wirblich C; Schnell MJ -
Modulation of type I IFN induction by a virulence determinant within the alphavirus nsP1 protein.
Virology Volume: 399 Page(s): 1 - 10
03/30/2010 Authors: Cruz CC; Suthar MS; Montgomery SA; Shabman R; Simmons J; Johnston RE; Morrison TE; Heise MT -
IPS-1 is essential for the control of West Nile virus infection and immunity.
PLoS Pathog Volume: 6 Page(s): e1000757
02/05/2010 Authors: Suthar MS; Ma DY; Thomas S; Lund JM; Zhang N; Daffis S; Rudensky AY; Bevan MJ; Clark EA; Kaja M-K -
Long double-stranded RNA induces an antiviral response independent of IFN regulatory factor 3, IFN-beta promoter stimulator 1, and IFN.
J Immunol Volume: 183 Page(s): 6545 - 6553
11/15/2009 Authors: DeWitte-Orr SJ; Mehta DR; Collins SE; Suthar MS; Gale M; Mossman KL -
Induction of IFN-beta and the innate antiviral response in myeloid cells occurs through an IPS-1-dependent signal that does not require IRF-3 and IRF-7.
PLoS Pathog Volume: 5 Page(s): e1000607
10/01/2009 Authors: Daffis S; Suthar MS; Szretter KJ; Gale M; Diamond MS -
Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses.
Cell Microbiol Volume: 11 Page(s): 880 - 888
06/01/2009 Authors: Suthar MS; Gale M; Owen DM -
Measure and countermeasure: type I IFN (IFN-alpha/beta) antiviral response against West Nile virus.
J Innate Immun Volume: 1 Page(s): 435 - 445
01/01/2009 Authors: Daffis S; Suthar MS; Gale M; Diamond MS -
Toll-like receptor 3 has a protective role against West Nile virus infection.
J Virol Volume: 82 Page(s): 10349 - 10358
11/01/2008 Authors: Daffis S; Samuel MA; Suthar MS; Gale M; Diamond MS -
Interferon regulatory factor IRF-7 induces the antiviral alpha interferon response and protects against lethal West Nile virus infection.
J Virol Volume: 82 Page(s): 8465 - 8475
09/01/2008 Authors: Daffis S; Samuel MA; Suthar MS; Keller BC; Gale M; Diamond MS -
Differential induction of type I interferon responses in myeloid dendritic cells by mosquito and mammalian-cell-derived alphaviruses.
J Virol Volume: 81 Page(s): 237 - 247
01/01/2007 Authors: Shabman RS; Morrison TE; Moore C; White L; Suthar MS; Hueston L; Rulli N; Lidbury B; Ting JP-Y; Mahalingam S -
Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants.
PLoS Med Volume: 3 Page(s): e525
12/01/2006 Authors: Deming D; Sheahan T; Heise M; Yount B; Davis N; Sims A; Suthar M; Harkema J; Whitmore A; Pickles R -
Ross river virus evasion of type I interferons
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE Volume: 73 Page(s): 193 - 193
12/01/2005 Authors: Shabman RS; Morrison TE; White L; Suthar MS; Madric K; Mahalingam S; Lidburyl B; Moore C; Heise MT -
Identification of adult mouse neurovirulence determinants of the Sindbis virus strain AR86.
J Virol Volume: 79 Page(s): 4219 - 4228
04/01/2005 Authors: Suthar MS; Shabman R; Madric K; Lambeth C; Heise MT -
Purification and characterization of hepatitis C virus non-structural protein 5A expressed in Escherichia coli.
Protein Expr Purif Volume: 37 Page(s): 144 - 153
09/01/2004 Authors: Huang L; Sineva EV; Hargittai MRS; Sharma SD; Suthar M; Raney KD; Cameron CE