Mark Prausnitz
- Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory
Adjunct Professor
Research
Publications
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Rapid local anesthesia in children enhanced by STAR particles: a first-in-humans, randomized clinical trial.
Drug Deliv Transl Res
06/23/2025 Authors: Tadros AR; Prausnitz MR; Felner EI -
High-velocity delivery of biologics via the gastrointestinal tract by self-pressurized oral capsules.
J Control Release Volume: 385 Page(s): 113963
06/18/2025 Authors: Palacios JI; Wood-Yang AJ; Klavohn N; Friesenhahn N; Raman N; Baker N; Ashby G; Prausnitz MR -
Perceptions of non-needle-based vaccination devices in the state of Georgia.
Vaccine Volume: 55 Page(s): 127038
05/10/2025 Authors: Melot L; Thyfault E; Hester K; Prausnitz MR; Bednarczyk RA -
A non-surgical method for subretinal delivery by trans-scleral microneedle injection.
Bioeng Transl Med Volume: 10 Page(s): e10755
05/01/2025 Authors: Hejri A; Chrenek MA; Goehring NT; Bowland II; Noel R; Yan J; Nickerson JM; Prausnitz MR -
Management of Levonorgestrel and Etonogestrel Adsorption to Polypropylene During in Vitro Release from Long-Acting Release Dosage Forms.
ACS Appl Mater Interfaces Volume: 17 Page(s): 23499 - 23512
04/23/2025 Authors: Zheng T; Dalvi A; Tang J; Chen JY; Schutzman R; Prausnitz MR; Schwendeman SP -
Suprachoroidal Drug Delivery for VEGF Suppression in Wet AMD and Other Diseases With Choroidal Neovascularization.
Am J Ophthalmol
04/23/2025 Authors: Chiang B; Chung YG; Prausnitz MR -
Thermostability of tetanus toxoid vaccine encapsulated in metal-organic frameworks.
Drug Deliv Transl Res
03/28/2025 Authors: Murty R; Walton KS; Prausnitz MR -
White paper: Understanding, informing and defining the regulatory science of microneedle-based dosage forms that are applied to the skin.
J Control Release Volume: 378 Page(s): 402 - 415
02/10/2025 Authors: Dul M; Alali M; Ameri M; Burke MD; Creelman BP; Dick L; Donnelly RF; Eakins MN; Frivold C; Forster AH -
Highly Water-Soluble Microneedle Patch for Short Wear Time and Rapid Drug Delivery.
Mol Pharm Volume: 22 Page(s): 573 - 582
01/06/2025 Authors: Wood-Yang AJ; Sankaranarayanan A; Freidlin MJ; Prausnitz MR -
Multi-Layered Microneedles Loaded with Microspheres.
AAPS PharmSciTech Volume: 26 Page(s): 19
01/03/2025 Authors: Tadros AR; Guo XD; Prausnitz MR -
IOP Reduction in Nonhuman Primates by Microneedle Injection of Drug-Free Hydrogel to Expand the Suprachoroidal Space.
Transl Vis Sci Technol Volume: 13 Page(s): 14
10/01/2024 Authors: Chung YG; Fan S; Gulati V; Li H-L; Gong H; Toris CB; Prausnitz MR; Ethier CR -
Feasibility of engineered Bacillus subtilis for use as a microbiome-based topical drug delivery platform.
Bioeng Transl Med Volume: 9 Page(s): e10645
07/01/2024 Authors: Montgomery VA; Wood-Yang AJ; Styczynski MP; Prausnitz MR -
Tolerability of a piezoelectric microneedle electroporator in human subjects.
Bioeng Transl Med Volume: 9 Page(s): e10662
07/01/2024 Authors: Lu C-Y; Rohilla P; Felner EI; Byagathvalli G; Azizoglu E; Bhamla MS; Prausnitz MR -
Computational modelling of scleral photocrosslinking: from rat to minipig to human.
J R Soc Interface Volume: 21 Page(s): 20240111
07/01/2024 Authors: Wood-Yang AJ; Gerberich BG; Prausnitz MR -
A measles and rubella vaccine microneedle patch in The Gambia: a phase 1/2, double-blind, double-dummy, randomised, active-controlled, age de-escalation trial.
Lancet Volume: 403 Page(s): 1879 - 1892
05/11/2024 Authors: Adigweme I; Yisa M; Ooko M; Akpalu E; Bruce A; Donkor S; Jarju LB; Danso B; Mendy A; Jeffries D -
Hybrid Lipid Nanocapsules: A Robust Platform for mRNA Delivery.
ACS Appl Mater Interfaces Volume: 16 Page(s): 15981 - 15992
04/03/2024 Authors: Yadava SK; Reddy BPK; Prausnitz MR; Cicerone MT -
The promise of microneedle technologies for drug delivery.
Drug Deliv Transl Res Volume: 14 Page(s): 573 - 580
03/01/2024 Authors: Donnelly RF; Prausnitz MR -
Microneedle patch-based enzyme-linked immunosorbent assay to quantify protein biomarkers of tuberculosis.
Biomed Microdevices Volume: 26 Page(s): 15
01/30/2024 Authors: Kim Y; Lewis MB; Hwang J; Wang Z; Gupta R; Liu Y; Gupta T; Barber JP; Singamaneni S; Quinn F -
Sweat induction using Pilocarpine microneedle patches for sweat testing in healthy adults.
J Cyst Fibros Volume: 23 Page(s): 112 - 119
01/01/2024 Authors: Chen JY; Li S; Silva GL; Chandler JD; Prausnitz MR; Guglani L -
Assessing the risk of a clinically significant infection from a Microneedle Array Patch (MAP) product.
J Control Release Volume: 361 Page(s): 236 - 245
09/01/2023 Authors: Dul M; Alali M; Ameri M; Burke MD; Craig CM; Creelman BP; Dick L; Donnelly RF; Eakins MN; Frivold C -
Modulation of hair growth by topical drug delivery enhanced by STAR particles.
J Control Release Volume: 361 Page(s): 766 - 776
09/01/2023 Authors: Woo MR; Prausnitz MR -
Author Correction: Intradermal immunization by Ebola virus GP subunit vaccines using microneedle patches protects mice against lethal EBOV challenge.
Sci Rep Volume: 13 Page(s): 13705
08/22/2023 Authors: Liu Y; Ye L; Lin F; Gomaa Y; Flyer D; Carrion R; Patterson JL; Prausnitz MR; Smith G; Glenn G -
Hepatitis B vaccine delivered by microneedle patch: Immunogenicity in mice and rhesus macaques.
Vaccine Volume: 41 Page(s): 3663 - 3672
06/01/2023 Authors: Choi Y; Lee GS; Li S; Lee JW; Mixson-Hayden T; Woo J; Xia D; Prausnitz MR; Kamili S; Purdy MA -
Tolerability, acceptability, and reproducibility of topical STAR particles in human subjects.
Bioeng Transl Med Volume: 8 Page(s): e10524
05/01/2023 Authors: Kim Y; Jung JH; Tadros AR; Prausnitz MR -
Interrogating Encapsulated Protein Structure within Metal-Organic Frameworks at Elevated Temperature.
J Am Chem Soc Volume: 145 Page(s): 7323 - 7330
04/05/2023 Authors: Murty R; Bera MK; Walton IM; Whetzel C; Prausnitz MR; Walton KS -
Suprachoroidal Delivery in Rats and Guinea Pigs Using a High-Precision Microneedle Injector.
Transl Vis Sci Technol Volume: 12 Page(s): 31
03/01/2023 Authors: Hejri A; Bowland II; Nickerson JM; Prausnitz MR -
Enhanced immune responses to vaccine antigens in the corneal stroma.
J Control Release Volume: 353 Page(s): 434 - 446
01/01/2023 Authors: Xia D; Toy R; Pradhan P; Hejri A; Chae J; Grossniklaus HE; Cursiefen C; Roy K; Prausnitz MR -
Bacillus subtilis engineered for topical delivery of an antifungal agent.
PLoS One Volume: 18 Page(s): e0293664
01/01/2023 Authors: Montgomery VA; Cain E; Styczynski MP; Prausnitz MR -
Skin Vaccination with Ebola Virus Glycoprotein Using a Polyphosphazene-Based Microneedle Patch Protects Mice against Lethal Challenge.
J Funct Biomater Volume: 14
12/27/2022 Authors: Romanyuk A; Wang R; Marin A; Janus BM; Felner EI; Xia D; Goez-Gazi Y; Alfson KJ; Yunus AS; Toth EA -
Six-month sustained delivery of anti-VEGF from in-situ forming hydrogel in the suprachoroidal space.
J Control Release Volume: 352 Page(s): 472 - 484
12/01/2022 Authors: Jung JH; Kim SS; Chung H; Hejri A; Prausnitz MR -
Microneedle Patches Loaded with Nanovesicles for Glucose Transporter-Mediated Insulin Delivery.
ACS Nano Volume: 16 Page(s): 18223 - 18231
11/22/2022 Authors: Chen Q; Xiao Z; Wang C; Chen G; Zhang Y; Zhang X; Han X; Wang J; Ye X; Prausnitz MR -
Role of drug delivery technologies in the success of COVID-19 vaccines: a perspective.
Drug Deliv Transl Res Volume: 12 Page(s): 2581 - 2588
11/01/2022 Authors: Labouta HI; Langer R; Cullis PR; Merkel OM; Prausnitz MR; Gomaa Y; Nogueira SS; Kumeria T -
Microneedle patch tattoos.
iScience Volume: 25 Page(s): 105014
10/21/2022 Authors: Li S; Kim Y; Lee JW; Prausnitz MR -
Clearing away barriers to oral drug delivery.
Sci Robot Volume: 7 Page(s): eade3311
09/28/2022 Authors: Xia D; Wood-Yang AJ; Prausnitz MR -
Study protocol for a phase 1/2, single-centre, double-blind, double-dummy, randomized, active-controlled, age de-escalation trial to assess the safety, tolerability and immunogenicity of a measles and rubella vaccine delivered by a microneedle patch in healthy adults (18 to 40 years), measles and rubella vaccine-primed toddlers (15 to 18 months) and measles and rubella vaccine-nave infants (9 to 10 months) in The Gambia [Measles and Rubella Vaccine Microneedle Patch Phase 1/2 Age De-escalation Trial].
Trials Volume: 23 Page(s): 775
09/14/2022 Authors: Adigweme I; Akpalu E; Yisa M; Donkor S; Jarju LB; Danso B; Mendy A; Jeffries D; Njie A; Bruce A -
Effect of Surface Interactions on Microsphere Loading in Dissolving Microneedle Patches.
ACS Appl Mater Interfaces Volume: 14 Page(s): 29577 - 29587
07/06/2022 Authors: Jang D; Tang J; Schwendeman SP; Prausnitz MR -
Computational modeling of corneal and scleral collagen photocrosslinking.
J Control Release Volume: 347 Page(s): 314 - 329
07/01/2022 Authors: Gerberich BG; Wood-Yang AJ; Radmand A; Nichols LM; Hejri A; Schrader Echeverri E; Gersch HG; Prausnitz MR -
Core-shell microneedle patch for six-month controlled-release contraceptive delivery.
J Control Release Volume: 347 Page(s): 489 - 499
07/01/2022 Authors: Li W; Chen JY; Terry RN; Tang J; Romanyuk A; Schwendeman SP; Prausnitz MR -
Evaluation of Spatially Targeted Scleral Stiffening on Neuroprotection in a Rat Model of Glaucoma.
Transl Vis Sci Technol Volume: 11 Page(s): 7
05/02/2022 Authors: Gerberich BG; Hannon BG; Brown DM; Read AT; Ritch MD; Schrader Echeverri E; Nichols L; Potnis C; Sridhar S; Toothman MG -
Continuous Ketone Monitoring Consensus Report 2021.
J Diabetes Sci Technol Volume: 16 Page(s): 689 - 715
05/01/2022 Authors: Nguyen KT; Xu NY; Zhang JY; Shang T; Basu A; Bergenstal RM; Castorino K; Chen KY; Kerr D; Koliwad SK -
Fabrication of pure-drug microneedles for delivery of montelukast sodium.
Drug Deliv Transl Res Volume: 12 Page(s): 444 - 458
02/01/2022 Authors: Azizoglu E; Ozer O; Prausnitz MR -
Angled Insertion of Microneedles for Targeted Antigen Delivery to the Epidermis.
Pharmaceutics Volume: 14
02/01/2022 Authors: Murty R; Sankaranarayanan A; Bowland II; Mena-Lapaix J; Prausnitz MR -
Coaxial electrospray of uniform polylactide core-shell microparticles for long-acting contraceptive.
J Control Release Volume: 341 Page(s): 634 - 645
01/01/2022 Authors: Tang J; Schutzman R; Rodrguez CA; Lahann J; Rodrguez-Hornedo N; Prausnitz MR; Schwendeman SP -
Microneedle patch designs to increase dose administered to human subjects.
J Control Release Volume: 339 Page(s): 350 - 360
11/10/2021 Authors: Li W; Li S; Fan X; Prausnitz MR -
An ultra-low-cost electroporator with microneedle electrodes (ePatch) for SARS-CoV-2 vaccination.
Proc Natl Acad Sci U S A Volume: 118
11/09/2021 Authors: Xia D; Jin R; Byagathvalli G; Yu H; Ye L; Lu C-Y; Bhamla MS; Yang C; Prausnitz MR -
Efficient Drug Delivery into Skin Using a Biphasic Dissolvable Microneedle Patch with Water-Insoluble Backing.
Adv Funct Mater Volume: 31
10/26/2021 Authors: Li S; Xia D; Prausnitz MR -
Optimization of intracellular macromolecule delivery by nanoparticle-mediated photoporation.
Nanomedicine Volume: 37 Page(s): 102431
10/01/2021 Authors: Kumar S; Li A; Thadhani NN; Prausnitz MR -
Thermostability of Measles and Rubella Vaccines in a Microneedle Patch.
Adv Ther (Weinh) Volume: 4
10/01/2021 Authors: Joyce JC; Collins ML; Rota PA; Prausnitz MR -
Development of a thermostable oxytocin microneedle patch.
J Control Release Volume: 337 Page(s): 81 - 89
09/10/2021 Authors: Gomaa Y; Kolluru C; Milewski M; Lee D; Zhang J; Saklatvala R; Prausnitz MR -
Immediate detachment of microneedles by interfacial fracture for sustained delivery of a contraceptive hormone in the skin.
J Control Release Volume: 337 Page(s): 676 - 685
09/10/2021 Authors: Lee Y; Li W; Tang J; Schwendeman SP; Prausnitz MR -
Administration of pilocarpine by microneedle patch as a novel method for cystic fibrosis sweat testing.
Bioeng Transl Med Volume: 6 Page(s): e10222
09/01/2021 Authors: Li S; Hart K; Norton N; Ryan CA; Guglani L; Prausnitz MR -
Corrigendum to "Using retinal function to define ischemic exclusion criteria for animal models of glaucoma" [Exp. Eye. Res. 202 (2021) 108354 doi: 10.1016/j.exer.2020.108354 Epub 2020 Nov 7].
Exp Eye Res Volume: 210 Page(s): 108699
09/01/2021 Authors: Hannon BG; Feola AJ; Gerberich BG; Read AT; Prausnitz MR; Ethier CR; Pardue MT -
Immunologic mechanisms of seasonal influenza vaccination administered by microneedle patch from a randomized phase I trial.
NPJ Vaccines Volume: 6 Page(s): 89
07/14/2021 Authors: Rouphael NG; Lai L; Tandon S; McCullough MP; Kong Y; Kabbani S; Natrajan MS; Xu Y; Zhu Y; Wang D -
Skin vaccination with dissolvable microneedle patches incorporating influenza neuraminidase and flagellin protein nanoparticles induces broad immune protection against multiple influenza viruses.
ACS Appl Bio Mater Volume: 4 Page(s): 4953 - 4961
06/21/2021 Authors: Wang Y; Li S; Dong C; Ma Y; Song Y; Zhu W; Kim J; Deng L; Denning TL; Kang S-M -
Fabrication of microneedle patches with lyophilized influenza vaccine suspended in organic solvent.
Drug Deliv Transl Res Volume: 11 Page(s): 692 - 701
04/01/2021 Authors: Kim YC; Lee JW; Esser ES; Kalluri H; Joyce JC; Compans RW; Skountzou I; Prausnitz MR -
Transpupillary collagen photocrosslinking for targeted modulation of ocular biomechanics.
Biomaterials Volume: 271 Page(s): 120735
04/01/2021 Authors: Gerberich BG; Hannon BG; Hejri A; Winger EJ; Schrader Echeverri E; Nichols LM; Gersch HG; MacLeod NA; Gupta S; Read AT -
Dissolvable Microneedle Patches to Enable Increased Access to Vaccines against SARS-CoV-2 and Future Pandemic Outbreaks.
Vaccines (Basel) Volume: 9
04/01/2021 Authors: O'Shea J; Prausnitz MR; Rouphael N -
Using retinal function to define ischemic exclusion criteria for animal models of glaucoma.
Exp Eye Res Volume: 202 Page(s): 108354
01/01/2021 Authors: Hannon BG; Feola AJ; Gerberich BG; Read AT; Prausnitz MR; Ethier CR; Pardue MT -
Effects of General Anesthesia on Intraocular Pressure in Rabbits.
J Am Assoc Lab Anim Sci Volume: 60 Page(s): 91 - 95
01/01/2021 Authors: Chae JJ; Prausnitz MR; Ethier CR -
Trends of microneedle technology in the scientific literature, patents, clinical trials and internet activity.
Biomaterials Volume: 267 Page(s): 120491
01/01/2021 Authors: Ingrole RSJ; Azizoglu E; Dul M; Birchall JC; Gill HS; Prausnitz MR -
Drug-Free, Nonsurgical Reduction of Intraocular Pressure for Four Months after Suprachoroidal Injection of Hyaluronic Acid Hydrogel.
Adv Sci (Weinh) Volume: 8 Page(s): 2001908
01/01/2021 Authors: Chae JJ; Jung JH; Zhu W; Gerberich BG; Bahrani Fard MR; Grossniklaus HE; Ethier CR; Prausnitz MR -
Sensitive sensing of biomarkers in interstitial fluid.
Nat Biomed Eng Volume: 5 Page(s): 3 - 5
01/01/2021 Authors: Kim Y; Prausnitz MR -
Serum Protects Cells and Increases Intracellular Delivery of Molecules by Nanoparticle-Mediated Photoporation.
Int J Nanomedicine Volume: 16 Page(s): 3707 - 3724
01/01/2021 Authors: Kumar S; Lazau E; Kim C; N Thadhani N; R Prausnitz M -
Sampling interstitial fluid from human skin using a microneedle patch.
Sci Transl Med Volume: 12
11/25/2020 Authors: Samant PP; Niedzwiecki MM; Raviele N; Tran V; Mena-Lapaix J; Walker DI; Felner EI; Jones DP; Miller GW; Prausnitz MR -
Acceptability of an inactivated influenza vaccine delivered by microneedle patch: Results from a phase I clinical trial of safety, reactogenicity, and immunogenicity.
Vaccine Volume: 38 Page(s): 7175 - 7181
10/21/2020 Authors: Frew PM; Paine MB; Rouphael N; Schamel J; Chung Y; Mulligan MJ; Prausnitz MR -
Cutaneous vaccination ameliorates Zika virus-induced neuro-ocular pathology via reduction of anti-ganglioside antibodies.
Hum Vaccin Immunother Volume: 16 Page(s): 2072 - 2091
09/01/2020 Authors: Beaver JT; Mills LK; Swieboda D; Lelutiu N; Esser ES; Antao OQ; Scountzou E; Williams DT; Papaioannou N; Littauer EQ -
A microneedle patch for measles and rubella vaccination: a game changer for achieving elimination.
Curr Opin Virol Volume: 41 Page(s): 68 - 76
04/01/2020 Authors: Prausnitz MR; Goodson JL; Rota PA; Orenstein WA -
STAR particles for enhanced topical drug and vaccine delivery.
Nat Med Volume: 26 Page(s): 341 - 347
03/01/2020 Authors: Tadros AR; Romanyuk A; Miller IC; Santiago A; Noel RK; O'Farrell L; Kwong GA; Prausnitz MR -
cGAMP/Saponin Adjuvant Combination Improves Protective Response to Influenza Vaccination by Microneedle Patch in an Aged Mouse Model.
Front Immunol Volume: 11 Page(s): 583251
01/01/2020 Authors: Vassilieva EV; Li S; Korniychuk H; Taylor DM; Wang S; Prausnitz MR; Compans RW -
Collagenase injection into the suprachoroidal space of the eye to expand drug delivery coverage and increase posterior drug targeting.
Exp Eye Res Volume: 189 Page(s): 107824
12/01/2019 Authors: Jung JH; Park S; Chae JJ; Prausnitz MR -
Feasibility of Hepatitis B Vaccination by Microneedle Patch: Cellular and Humoral Immunity Studies in Rhesus Macaques.
J Infect Dis Volume: 220 Page(s): 1926 - 1934
11/06/2019 Authors: Choi YH; Perez-Cuevas MB; Kodani M; Zhang X; Prausnitz MR; Kamili S; O'Connor SM -
Long-acting reversible contraception by effervescent microneedle patch.
Sci Adv Volume: 5 Page(s): eaaw8145
11/01/2019 Authors: Li W; Tang J; Terry RN; Li S; Brunie A; Callahan RL; Noel RK; Rodrguez CA; Schwendeman SP; Prausnitz MR -
Sustained scleral stiffening in rats after a single genipin treatment.
J R Soc Interface Volume: 16 Page(s): 20190427
10/31/2019 Authors: Hannon BG; Schwaner SA; Boazak EM; Gerberich BG; Winger EJ; Prausnitz MR; Ethier CR -
Microneedle patch drug delivery in the gut.
Nat Med Volume: 25 Page(s): 1471 - 1472
10/01/2019 Authors: Prausnitz MR; Gomaa Y; Li W -
Targeting drug delivery within the suprachoroidal space.
Drug Discov Today Volume: 24 Page(s): 1654 - 1659
08/01/2019 Authors: Jung JH; Chae JJ; Prausnitz MR -
Plasmonic Paper Microneedle Patch for On-Patch Detection of Molecules in Dermal Interstitial Fluid.
ACS Sens Volume: 4 Page(s): 1569 - 1576
06/28/2019 Authors: Kolluru C; Gupta R; Jiang Q; Williams M; Gholami Derami H; Cao S; Noel RK; Singamaneni S; Prausnitz MR -
[Extended delivery of vaccines to the skin improves immune responses].
J Control Release Volume: 304 Page(s): 135 - 145
06/28/2019 Authors: Joyce JC; Sella HE; Jost H; Mistilis MJ; Esser ES; Pradhan P; Toy R; Collins ML; Rota PA; Roy K -
Genomic DNA in a dissolvable microneedle patch acts as strong immunostimulator
Volume: 493 Page(s): S544 - S544
06/01/2019 Authors: Mohan T; Li S; Gonzalez GX; Prausnitz M; Wang B -
Pharmaceutical jewelry: Earring patch for transdermal delivery of contraceptive hormone.
J Control Release Volume: 301 Page(s): 140 - 145
05/10/2019 Authors: Mofidfar M; O'Farrell L; Prausnitz MR -
Co-Delivery of M2e Virus-Like Particles with Influenza Split Vaccine to the Skin Using Microneedles Enhances the Efficacy of Cross Protection.
Pharmaceutics Volume: 11
04/18/2019 Authors: Kim M-C; Kim K-H; Lee JW; Lee Y-N; Choi H-J; Jung Y-J; Kim Y-J; Compans RW; Prausnitz MR; Kang S-M -
Rapidly separable microneedle patch for the sustained release of a contraceptive.
Nat Biomed Eng Volume: 3 Page(s): 220 - 229
03/01/2019 Authors: Li W; Terry RN; Tang J; Feng MR; Schwendeman SP; Prausnitz MR -
Monitoring drug pharmacokinetics and immunologic biomarkers in dermal interstitial fluid using a microneedle patch.
Biomed Microdevices Volume: 21 Page(s): 14
02/06/2019 Authors: Kolluru C; Williams M; Yeh JS; Noel RK; Knaack J; Prausnitz MR -
Development of a thermostable microneedle patch for polio vaccination.
Drug Deliv Transl Res Volume: 9 Page(s): 192 - 203
02/01/2019 Authors: Kolluru C; Gomaa Y; Prausnitz MR -
Recruitment and Collection of Dermal Interstitial Fluid Using a Microneedle Patch.
Adv Healthc Mater Volume: 8 Page(s): e1801262
02/01/2019 Authors: Kolluru C; Williams M; Chae J; Prausnitz MR -
Self-healing encapsulation and controlled release of vaccine antigens from PLGA microparticles delivered by microneedle patches.
Bioeng Transl Med Volume: 4 Page(s): 116 - 128
01/01/2019 Authors: Mazzara JM; Ochyl LJ; Hong JKY; Moon JJ; Prausnitz MR; Schwendeman SP -
Electrospun Transdermal Patch for Contraceptive Hormone Delivery.
Curr Drug Deliv Volume: 16 Page(s): 577 - 583
01/01/2019 Authors: Mofidfar M; Prausnitz MR -
Intradermal Vaccination With Adjuvanted Ebola Virus Soluble Glycoprotein Subunit Vaccine by Microneedle Patches Protects Mice Against Lethal Ebola Virus Challenge.
J Infect Dis Volume: 218 Page(s): S545 - S552
11/22/2018 Authors: Liu Y; Ye L; Lin F; Gomaa Y; Flyer D; Carrion R; Patterson JL; Prausnitz MR; Smith G; Glenn G -
Individually coated microneedles for co-delivery of multiple compounds with different properties.
Drug Deliv Transl Res Volume: 8 Page(s): 1043 - 1052
10/01/2018 Authors: Li S; Li W; Prausnitz M -
Hepatitis B vaccination using a dissolvable microneedle patch is immunogenic in mice and rhesus macaques.
Bioeng Transl Med Volume: 3 Page(s): 186 - 196
09/01/2018 Authors: Perez Cuevas MB; Kodani M; Choi Y; Joyce J; O'Connor SM; Kamili S; Prausnitz MR -
STAR particles for enhanced topical delivery to skin
Volume: 138 Page(s): B19 - B19
09/01/2018 Authors: Tadros A; Prausnitz M -
Heterosubtypic influenza protection elicited by double-layered polypeptide nanoparticles in mice.
Proc Natl Acad Sci U S A Volume: 115 Page(s): E7758 - E7767
08/14/2018 Authors: Deng L; Chang TZ; Wang Y; Li S; Wang S; Matsuyama S; Yu G; Compans RW; Li J-D; Prausnitz MR -
Intradermal immunization by Ebola virus GP subunit vaccines using microneedle patches protects mice against lethal EBOV challenge.
Sci Rep Volume: 8 Page(s): 11193
07/25/2018 Authors: Liu Y; Ye L; Lin F; Gomaa Y; Flyer D; Carrion R; Patterson JL; Prausnitz MR; Smith G; Glenn G -
Effect of laser fluence, nanoparticle concentration and total energy input per cell on photoporation of cells.
Nanomedicine Volume: 14 Page(s): 1667 - 1677
07/01/2018 Authors: Holguin SY; Thadhani NN; Prausnitz MR -
A Microneedle Patch for Measles and Rubella Vaccination Is Immunogenic and Protective in Infant Rhesus Macaques.
J Infect Dis Volume: 218 Page(s): 124 - 132
06/05/2018 Authors: Joyce JC; Carroll TD; Collins ML; Chen M-H; Fritts L; Dutra JC; Rourke TL; Goodson JL; McChesney MB; Prausnitz MR -
Drug delivery using microneedle patches: not just for skin.
Expert Opin Drug Deliv Volume: 15 Page(s): 541 - 543
06/01/2018 Authors: Lee JW; Prausnitz MR -
Ocular drug delivery targeted by iontophoresis in the suprachoroidal space using a microneedle.
J Control Release Volume: 277 Page(s): 14 - 22
05/10/2018 Authors: Jung JH; Chiang B; Grossniklaus HE; Prausnitz MR -
Mechanisms of sampling interstitial fluid from skin using a microneedle patch.
Proc Natl Acad Sci U S A Volume: 115 Page(s): 4583 - 4588
05/01/2018 Authors: Samant PP; Prausnitz MR -
Risk factors for influenza-related complications in children during the 2009/10 pandemic: a UK primary care cohort study using linked routinely collected data
EPIDEMIOLOGY AND INFECTION Volume: 146 Page(s): 817 - 823
05/01/2018 Authors: Lee JJ; Bankhead C; Smith M; Kousoulis AA; Butler CC; Wang K -
Stable incorporation of GM-CSF into dissolvable microneedle patch improves skin vaccination against influenza.
J Control Release Volume: 276 Page(s): 1 - 16
04/28/2018 Authors: Littauer EQ; Mills LK; Brock N; Esser ES; Romanyuk A; Pulit-Penaloza JA; Vassilieva EV; Beaver JT; Antao O; Krammer F -
Targeted Drug Delivery in the Suprachoroidal Space by Swollen Hydrogel Pushing.
Invest Ophthalmol Vis Sci Volume: 59 Page(s): 2069 - 2079
04/01/2018 Authors: Jung JH; Desit P; Prausnitz MR -
Human Suction Blister Fluid Composition Determined Using High-Resolution Metabolomics.
Anal Chem Volume: 90 Page(s): 3786 - 3792
03/20/2018 Authors: Niedzwiecki MM; Samant P; Walker DI; Tran V; Jones DP; Prausnitz MR; Miller GW -
Photoporation Using Carbon Nanotubes for Intracellular Delivery of Molecules and Its Relationship to Photoacoustic Pressure.
Adv Healthc Mater Volume: 7
03/01/2018 Authors: Holguin SY; Gray MD; Joseph P; Thadhani NN; Prausnitz MR -
The suprachoroidal space as a route of administration to the posterior segment of the eye.
Adv Drug Deliv Rev Volume: 126 Page(s): 58 - 66
02/15/2018 Authors: Chiang B; Jung JH; Prausnitz MR -
Inactivated rotavirus vaccine by parenteral administration induces mucosal immunity in mice.
Sci Rep Volume: 8 Page(s): 561
01/12/2018 Authors: Resch TK; Wang Y; Moon S-S; Joyce J; Li S; Prausnitz M; Jiang B -
Enhanced Immune Responses Conferring Cross-Protection by Skin Vaccination With a Tri-Component Influenza Vaccine Using a Microneedle Patch.
Front Immunol Volume: 9 Page(s): 1705
01/01/2018 Authors: Zhu W; Li S; Wang C; Yu G; Prausnitz MR; Wang B-Z -
Vaccination by microneedle patch with inactivated respiratory syncytial virus and monophosphoryl lipid A enhances the protective efficacy and diminishes inflammatory disease after challenge.
PLoS One Volume: 13 Page(s): e0205071
01/01/2018 Authors: Park S; Lee Y; Kwon Y-M; Lee Y-T; Kim K-H; Ko E-J; Jung JH; Song M; Graham B; Prausnitz MR -
Dihydroergotamine mesylate-loaded dissolving microneedle patch made of polyvinylpyrrolidone for management of acute migraine therapy.
J Control Release Volume: 268 Page(s): 159 - 165
12/28/2017 Authors: Tas C; Joyce JC; Nguyen HX; Eangoor P; Knaack JS; Banga AK; Prausnitz MR -
Skin immunization by microneedle patch overcomes statin-induced suppression of immune responses to influenza vaccine.
Sci Rep Volume: 7 Page(s): 17855
12/19/2017 Authors: Vassilieva EV; Wang S; Li S; Prausnitz MR; Compans RW -
Editorial.
J Control Release Volume: 265 Page(s): 1
11/10/2017 Authors: Grath MM; Coulman S; Birchall J; Prausnitz M -
Role of cytoskeletal mechanics and cell membrane fluidity in the intracellular delivery of molecules mediated by laser-activated carbon nanoparticles.
Biotechnol Bioeng Volume: 114 Page(s): 2390 - 2399
10/01/2017 Authors: Holguin SY; Anderson CF; Thadhani NN; Prausnitz MR -
A boosting skin vaccination with dissolving microneedle patch encapsulating M2e vaccine broadens the protective efficacy of conventional influenza vaccines.
J Control Release Volume: 261 Page(s): 1 - 9
09/10/2017 Authors: Zhu W; Pewin W; Wang C; Luo Y; Gonzalez GX; Mohan T; Prausnitz MR; Wang B-Z -
Iontophoretic targeting of drug delivery in the eye via the suprachoroidal space
Volume: 95
09/01/2017 Authors: Jung JH; Chiang B; Prausnitz M -
The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial.
Lancet Volume: 390 Page(s): 649 - 658
08/12/2017 Authors: Rouphael NG; Paine M; Mosley R; Henry S; McAllister DV; Kalluri H; Pewin W; Frew PM; Yu T; Thornburg NJ -
Microneedle patch delivery of influenza vaccine during pregnancy enhances maternal immune responses promoting survival and long-lasting passive immunity to offspring.
Sci Rep Volume: 7 Page(s): 5705
07/18/2017 Authors: Esser ES; Pulit-Penaloza JA; Kalluri H; McAllister D; Vassilieva EV; Littauer EQ; Lelutiu N; Prausnitz MR; Compans RW; Skountzou I -
Engineering Microneedle Patches for Vaccination and Drug Delivery to Skin.
Annu Rev Chem Biomol Eng Volume: 8 Page(s): 177 - 200
06/07/2017 Authors: Prausnitz MR -
Tolerability, usability and acceptability of dissolving microneedle patch administration in human subjects.
Biomaterials Volume: 128 Page(s): 1 - 7
06/01/2017 Authors: Arya J; Henry S; Kalluri H; McAllister DV; Pewin WP; Prausnitz MR -
Challenges and Future Prospects for the Delivery of Biologics: Oral Mucosal, Pulmonary, and Transdermal Routes.
AAPS J Volume: 19 Page(s): 652 - 668
05/01/2017 Authors: Morales JO; Fathe KR; Brunaugh A; Ferrati S; Li S; Montenegro-Nicolini M; Mousavikhamene Z; McConville JT; Prausnitz MR; Smyth HDC -
Long-term stability of influenza vaccine in a dissolving microneedle patch.
Drug Deliv Transl Res Volume: 7 Page(s): 195 - 205
04/01/2017 Authors: Mistilis MJ; Joyce JC; Esser ES; Skountzou I; Compans RW; Bommarius AS; Prausnitz MR -
Energy Transfer Mechanisms during Molecular Delivery to Cells by Laser-Activated Carbon Nanoparticles.
Biophys J Volume: 112 Page(s): 1258 - 1269
03/28/2017 Authors: Sengupta A; Gray MD; Kelly SC; Holguin SY; Thadhani NN; Prausnitz MR -
Ebola Vaccination Using a DNA Vaccine Coated on PLGA-PLL/PGA Nanoparticles Administered Using a Microneedle Patch.
Adv Healthc Mater Volume: 6
01/01/2017 Authors: Yang H-W; Ye L; Guo XD; Yang C; Compans RW; Prausnitz MR -
Thickness and Closure Kinetics of the Suprachoroidal Space Following Microneedle Injection of Liquid Formulations.
Invest Ophthalmol Vis Sci Volume: 58 Page(s): 555 - 564
01/01/2017 Authors: Chiang B; Venugopal N; Grossniklaus HE; Jung JH; Edelhauser HF; Prausnitz MR -
Clearance Kinetics and Clearance Routes of Molecules From the Suprachoroidal Space After Microneedle Injection.
Invest Ophthalmol Vis Sci Volume: 58 Page(s): 545 - 554
01/01/2017 Authors: Chiang B; Wang K; Ethier CR; Prausnitz MR -
Distribution of particles, small molecules and polymeric formulation excipients in the suprachoroidal space after microneedle injection.
Exp Eye Res Volume: 153 Page(s): 101 - 109
12/01/2016 Authors: Chiang B; Venugopal N; Edelhauser HF; Prausnitz MR -
Targeted Drug Delivery Within the Eye Through the Suprachoroidal Space.
J Ocul Pharmacol Ther Volume: 32 Page(s): 640 - 641
12/01/2016 Authors: Patel SR; Prausnitz MR -
Microneedle patches for vaccination in developing countries.
J Control Release Volume: 240 Page(s): 135 - 141
10/28/2016 Authors: Arya J; Prausnitz MR -
Rabies vaccination in dogs using a dissolving microneedle patch.
J Control Release Volume: 239 Page(s): 19 - 26
10/10/2016 Authors: Arya JM; Dewitt K; Scott-Garrard M; Chiang Y-W; Prausnitz MR -
Distribution and Clearance of Particles and Molecules after Microneedle Injection into the Suprachoroidal Space
Volume: 57
09/01/2016 Authors: Chiang B; Prausnitz MR -
Electric field-mediated targeting of drug delivery in the suprachoroidal space
Volume: 57
09/01/2016 Authors: Jung JH; Chiang B; Prausnitz MR -
Tetanus vaccination with a dissolving microneedle patch confers protective immune responses in pregnancy.
J Control Release Volume: 236 Page(s): 47 - 56
08/28/2016 Authors: Esser ES; Romanyuk A; Vassilieva EV; Jacob J; Prausnitz MR; Compans RW; Skountzou I -
DNA uptake, intracellular trafficking and gene transfection after ultrasound exposure.
J Control Release Volume: 234 Page(s): 1 - 9
07/28/2016 Authors: Liu Y; Yan J; Santangelo PJ; Prausnitz MR -
Parameters affecting intracellular delivery of molecules using laser-activated carbon nanoparticles.
Nanomedicine Volume: 12 Page(s): 1003 - 1011
05/01/2016 Authors: Chakravarty P; Lane CD; Orlando TM; Prausnitz MR -
Immunization with synthetic LbL microparticle vaccine administered using a microneedle patch elicits humoral and cellular immune responses and protects mice from challenge with respiratory syncytial virus
Volume: 196
05/01/2016 Authors: Powell TJ; Mistillis M; Palath N; Tang J; Jacobs A; Cardenas E; Boyd JG; Prausnitz M -
Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma.
J Control Release Volume: 228 Page(s): 48 - 57
04/28/2016 Authors: Chiang B; Kim YC; Doty AC; Grossniklaus HE; Schwendeman SP; Prausnitz MR -
Enhanced Stability of Inactivated Influenza Vaccine Encapsulated in Dissolving Microneedle Patches.
Pharm Res Volume: 33 Page(s): 868 - 878
04/01/2016 Authors: Chu LY; Ye L; Dong K; Compans RW; Yang C; Prausnitz MR -
Circumferential flow of particles in the suprachoroidal space is impeded by the posterior ciliary arteries.
Exp Eye Res Volume: 145 Page(s): 424 - 431
04/01/2016 Authors: Chiang B; Kim YC; Edelhauser HF; Prausnitz MR -
Intracellular delivery of molecules using microfabricated nanoneedle arrays.
Biomed Microdevices Volume: 18 Page(s): 10
02/01/2016 Authors: Park S; Choi S-O; Paik S-J; Choi S; Allen M; Prausnitz M -
Inkjet printing of transdermal microneedles for the delivery of anticancer agents.
Int J Pharm Volume: 494 Page(s): 593 - 602
10/30/2015 Authors: Uddin MJ; Scoutaris N; Klepetsanis P; Chowdhry B; Prausnitz MR; Douroumis D -
Enhanced immune responses by skin vaccination with influenza subunit vaccine in young hosts.
Vaccine Volume: 33 Page(s): 4675 - 4682
09/08/2015 Authors: Koutsonanos DG; Esser ES; McMaster SR; Kalluri P; Lee J-W; Prausnitz MR; Skountzou I; Denning TL; Kohlmeier JE; Compans RW -
An economic model assessing the value of microneedle patch delivery of the seasonal influenza vaccine.
Vaccine Volume: 33 Page(s): 4727 - 4736
09/08/2015 Authors: Lee BY; Bartsch SM; Mvundura M; Jarrahian C; Zapf KM; Marinan K; Wateska AR; Snyder B; Swaminathan S; Jacoby E -
A microneedle patch containing measles vaccine is immunogenic in non-human primates.
Vaccine Volume: 33 Page(s): 4712 - 4718
09/08/2015 Authors: Edens C; Collins ML; Goodson JL; Rota PA; Prausnitz MR -
Inactivated polio vaccination using a microneedle patch is immunogenic in the rhesus macaque.
Vaccine Volume: 33 Page(s): 4683 - 4690
09/08/2015 Authors: Edens C; Dybdahl-Sissoko NC; Weldon WC; Oberste MS; Prausnitz MR -
Formulation to target delivery to the ciliary body and choroid via the suprachoroidal space of the eye using microneedles.
Eur J Pharm Biopharm Volume: 95 Page(s): 398 - 406
09/01/2015 Authors: Kim YC; Oh KH; Edelhauser HF; Prausnitz MR -
Enhanced transdermal delivery of anti-inflammatory drugs synthesized as ionic liquids
Volume: 250
08/16/2015 Authors: Medina-Ramos W; Prausnitz M -
Improved immunogenicity of individual influenza vaccine components delivered with a novel dissolving microneedle patch stable at room temperature.
Drug Deliv Transl Res Volume: 5 Page(s): 360 - 371
08/01/2015 Authors: Vassilieva EV; Kalluri H; McAllister D; Taherbhai MT; Esser ES; Pewin WP; Pulit-Penaloza JA; Prausnitz MR; Compans RW; Skountzou I -
Microneedle patch delivery to the skin of virus-like particles containing heterologous M2e extracellular domains of influenza virus induces broad heterosubtypic cross-protection.
J Control Release Volume: 210 Page(s): 208 - 216
07/28/2015 Authors: Kim M-C; Lee JW; Choi H-J; Lee Y-N; Hwang HS; Lee J; Kim C; Lee JS; Montemagno C; Prausnitz MR -
Pharmacokinetics and Clearance of Molecules after Microneedle Injection into the Suprachoroidal Space
Volume: 56
06/01/2015 Authors: Chiang B; Prausnitz MR -
Drug delivery: Puncturing cells en masse.
Nat Mater Volume: 14 Page(s): 470 - 471
05/01/2015 Authors: Prausnitz MR -
Poloxamer surfactant preserves cell viability during photoacoustic delivery of molecules into cells.
Biotechnol Bioeng Volume: 112 Page(s): 405 - 415
02/01/2015 Authors: Sengupta A; Dwivedi N; Kelly SC; Tucci L; Thadhani NN; Prausnitz MR -
Development of a thermostable microneedle patch for influenza vaccination.
J Pharm Sci Volume: 104 Page(s): 740 - 749
02/01/2015 Authors: Mistilis MJ; Bommarius AS; Prausnitz MR -
Vaccination with human papillomavirus pseudovirus-encapsidated plasmids targeted to skin using microneedles.
PLoS One Volume: 10 Page(s): e0120797
01/01/2015 Authors: Kines RC; Zarnitsyn V; Johnson TR; Pang Y-YS; Corbett KS; Nicewonger JD; Gangopadhyay A; Chen M; Liu J; Prausnitz MR -
Delivery of siRNA to ovarian cancer cells using laser-activated carbon nanoparticles.
Nanomedicine (Lond) Volume: 10 Page(s): 1775 - 1784
01/01/2015 Authors: Sengupta A; Mezencev R; McDonald JF; Prausnitz MR -
Effect of Osmotic Pressure on the Stability of Whole Inactivated Influenza Vaccine for Coating on Microneedles.
PLoS One Volume: 10 Page(s): e0134431
01/01/2015 Authors: Choi H-J; Song J-M; Bondy BJ; Compans RW; Kang S-M; Prausnitz MR -
Collection of analytes from microneedle patches.
Anal Chem Volume: 86 Page(s): 10520 - 10523
11/04/2014 Authors: Romanyuk AV; Zvezdin VN; Samant P; Grenader MI; Zemlyanova M; Prausnitz MR -
Ocular delivery of macromolecules.
J Control Release Volume: 190 Page(s): 172 - 181
09/28/2014 Authors: Kim YC; Chiang B; Wu X; Prausnitz MR -
Targeted delivery of antiglaucoma drugs to the supraciliary space using microneedles.
Invest Ophthalmol Vis Sci Volume: 55 Page(s): 7387 - 7397
09/11/2014 Authors: Kim YC; Edelhauser HF; Prausnitz MR -
Intrastromal delivery of bevacizumab using microneedles to treat corneal neovascularization.
Invest Ophthalmol Vis Sci Volume: 55 Page(s): 7376 - 7386
09/11/2014 Authors: Kim YC; Grossniklaus HE; Edelhauser HF; Prausnitz MR -
A protective role of murine langerin cells in immune responses to cutaneous vaccination with microneedle patches.
Sci Rep Volume: 4 Page(s): 6094
08/18/2014 Authors: Pulit-Penaloza JA; Esser ES; Vassilieva EV; Lee JW; Taherbhai MT; Pollack BP; Prausnitz MR; Compans RW; Skountzou I -
Particle-stabilized emulsion droplets for gravity-mediated targeting in the posterior segment of the eye.
Adv Healthc Mater Volume: 3 Page(s): 1272 - 1282
08/01/2014 Authors: Kim YC; Edelhauser HF; Prausnitz MR -
Microneedle patches: usability and acceptability for self-vaccination against influenza.
Vaccine Volume: 32 Page(s): 1856 - 1862
04/01/2014 Authors: Norman JJ; Arya JM; McClain MA; Frew PM; Meltzer MI; Prausnitz MR -
Reliability and accuracy of intradermal injection by Mantoux technique, hypodermic needle adapter, and hollow microneedle in pigs.
Drug Deliv Transl Res Volume: 4 Page(s): 126 - 130
04/01/2014 Authors: Norman JJ; Gupta J; Patel SR; Park S; Jarrahian C; Zehrung D; Prausnitz MR -
Parametric assessment of acoustic output from laser-irradiated nanoparticle volumes.
J Acoust Soc Am Volume: 135 Page(s): 2373
04/01/2014 Authors: Gray MD; Sengupta A; Prausnitz MR -
The long posterior ciliary arteries block circumferential flow in the suprachoroidal space of the rabbit eye
Volume: 55
04/01/2014 Authors: Chiang B; Kim YC; Prausnitz MR -
Targeted delivery of anti-glaucoma drugs to the supraciliary space using microneedles
Volume: 55
04/01/2014 Authors: Kim YC; Prausnitz MR; Edelhauser HF -
Microneedle delivery of an M2e-TLR5 ligand fusion protein to skin confers broadly cross-protective influenza immunity.
J Control Release Volume: 178 Page(s): 1 - 7
03/28/2014 Authors: Wang B-Z; Gill HS; He C; Ou C; Wang L; Wang Y-C; Feng H; Zhang H; Prausnitz MR; Compans RW -
Efficient intracellular delivery of molecules with high cell viability using nanosecond-pulsed laser-activated carbon nanoparticles.
ACS Nano Volume: 8 Page(s): 2889 - 2899
03/25/2014 Authors: Sengupta A; Kelly SC; Dwivedi N; Thadhani N; Prausnitz MR -
Cross-protection by co-immunization with influenza hemagglutinin DNA and inactivated virus vaccine using coated microneedles.
J Control Release Volume: 172 Page(s): 579 - 588
12/10/2013 Authors: Kim Y-C; Yoo D-G; Compans RW; Kang S-M; Prausnitz MR -
Skin pretreatment with microneedles prior to pilocarpine iontophoresis increases sweat production.
Clin Physiol Funct Imaging Volume: 33 Page(s): 436 - 440
11/01/2013 Authors: Wing D; Prausnitz MR; Buono MJ -
Faster pharmacokinetics and increased patient acceptance of intradermal insulin delivery using a single hollow microneedle in children and adolescents with type 1 diabetes.
Pediatr Diabetes Volume: 14 Page(s): 459 - 465
09/01/2013 Authors: Norman JJ; Brown MR; Raviele NA; Prausnitz MR; Felner EI -
Long-term protective immunity from an influenza virus-like particle vaccine administered with a microneedle patch.
Clin Vaccine Immunol Volume: 20 Page(s): 1433 - 1439
09/01/2013 Authors: Quan F-S; Kim Y-C; Song J-M; Hwang HS; Compans RW; Prausnitz MR; Kang S-M -
Measles vaccination using a microneedle patch.
Vaccine Volume: 31 Page(s): 3403 - 3409
07/25/2013 Authors: Edens C; Collins ML; Ayers J; Rota PA; Prausnitz MR -
Dose sparing and enhanced immunogenicity of inactivated rotavirus vaccine administered by skin vaccination using a microneedle patch.
Vaccine Volume: 31 Page(s): 3396 - 3402
07/25/2013 Authors: Moon S; Wang Y; Edens C; Gentsch JR; Prausnitz MR; Jiang B -
Distribution And Clearance Of Microparticles And Nanoparticles In The Suprachoroidal Space After Injection Using Hollow Microneedles In Rabbits
Volume: 54
06/01/2013 Authors: Kim Y; Prausnitz M; Edelhauser H -
Transdermal delivery of molecules is limited by full epidermis, not just stratum corneum.
Pharm Res Volume: 30 Page(s): 1099 - 1109
04/01/2013 Authors: Andrews SN; Jeong E; Prausnitz MR -
Hollow microneedles for intradermal injection fabricated by sacrificial micromolding and selective electrodeposition.
Biomed Microdevices Volume: 15 Page(s): 203 - 210
04/01/2013 Authors: Norman JJ; Choi S-O; Tong NT; Aiyar AR; Patel SR; Prausnitz MR; Allen MG -
Stability of whole inactivated influenza virus vaccine during coating onto metal microneedles.
J Control Release Volume: 166 Page(s): 159 - 171
03/10/2013 Authors: Choi H-J; Bondy BJ; Yoo D-G; Compans RW; Kang S-M; Prausnitz MR -
Pocketed microneedles for rapid delivery of a liquid-state botulinum toxin A formulation into human skin.
J Control Release Volume: 165 Page(s): 146 - 152
01/28/2013 Authors: Torrisi BM; Zarnitsyn V; Prausnitz MR; Anstey A; Gateley C; Birchall JC; Coulman SA -
Microneedles for drug and vaccine delivery.
Adv Drug Deliv Rev Volume: 64 Page(s): 1547 - 1568
11/01/2012 Authors: Kim Y-C; Park J-H; Prausnitz MR -
DNA vaccination in the skin using microneedles improves protection against influenza.
Mol Ther Volume: 20 Page(s): 1472 - 1480
07/01/2012 Authors: Song J-M; Kim Y-C; O E; Compans RW; Prausnitz MR; Kang S-M -
Microelectronic control of drug delivery.
Expert Rev Med Devices Volume: 9 Page(s): 323 - 326
07/01/2012 Authors: Guo XD; Prausnitz MR -
Targeted administration into the suprachoroidal space using a microneedle for drug delivery to the posterior segment of the eye.
Invest Ophthalmol Vis Sci Volume: 53 Page(s): 4433 - 4441
07/01/2012 Authors: Patel SR; Berezovsky DE; McCarey BE; Zarnitsyn V; Edelhauser HF; Prausnitz MR -
Increased immunogenicity of avian influenza DNA vaccine delivered to the skin using a microneedle patch.
Eur J Pharm Biopharm Volume: 81 Page(s): 239 - 247
06/01/2012 Authors: Kim Y-C; Song J-M; Lipatov AS; Choi S-O; Lee JW; Donis RO; Compans RW; Kang S-M; Prausnitz MR -
Stability of influenza vaccine coated onto microneedles.
Biomaterials Volume: 33 Page(s): 3756 - 3769
05/01/2012 Authors: Choi H-J; Yoo D-G; Bondy BJ; Quan F-S; Compans RW; Kang S-M; Prausnitz MR -
Rapid release of plasmid DNA from surfaces coated with polyelectrolyte multilayers promoted by the application of electrochemical potentials.
ACS Appl Mater Interfaces Volume: 4 Page(s): 2726 - 2734
05/01/2012 Authors: Aytar BS; Prausnitz MR; Lynn DM -
Can ultrasound enable efficient intracellular uptake of molecules? A retrospective literature review and analysis.
Ultrasound Med Biol Volume: 38 Page(s): 876 - 888
05/01/2012 Authors: Liu Y; Yan J; Prausnitz MR -
Intracellular protein delivery and gene transfection by electroporation using a microneedle electrode array.
Small Volume: 8 Page(s): 1081 - 1091
04/10/2012 Authors: Choi S-O; Kim Y-C; Lee JW; Park J-H; Prausnitz MR; Allen MG -
Improving patient acceptance of insulin therapy by improving needle design.
J Diabetes Sci Technol Volume: 6 Page(s): 336 - 338
03/01/2012 Authors: Norman JJ; Prausnitz MR -
Microchip for sustained drug delivery by diffusion through microchannels.
AAPS PharmSciTech Volume: 13 Page(s): 211 - 217
03/01/2012 Authors: Lee SH; Park M; Park CG; Lee JE; Prausnitz MR; Choy YB -
Delivery of salmon calcitonin using a microneedle patch.
Int J Pharm Volume: 423 Page(s): 257 - 263
02/28/2012 Authors: Tas C; Mansoor S; Kalluri H; Zarnitsyn VG; Choi S-O; Banga AK; Prausnitz MR -
Rapid local anesthesia in humans using minimally invasive microneedles.
Clin J Pain Volume: 28 Page(s): 129 - 135
02/01/2012 Authors: Gupta J; Denson DD; Felner EI; Prausnitz MR -
Local response to microneedle-based influenza immunization in the skin.
mBio Volume: 3 Page(s): e00012 - e00012
01/01/2012 Authors: del Pilar Martin M; Weldon WC; Zarnitsyn VG; Koutsonanos DG; Akbari H; Skountzou I; Jacob J; Prausnitz MR; Compans RW -
Effect of adjuvants on responses to skin immunization by microneedles coated with influenza subunit vaccine.
PLoS One Volume: 7 Page(s): e41501
01/01/2012 Authors: Weldon WC; Zarnitsyn VG; Esser ES; Taherbhai MT; Koutsonanos DG; Vassilieva EV; Skountzou I; Prausnitz MR; Compans RW -
Delivery of subunit influenza vaccine to skin with microneedles improves immunogenicity and long-lived protection.
Sci Rep Volume: 2 Page(s): 357
01/01/2012 Authors: Koutsonanos DG; Vassilieva EV; Stavropoulou A; Zarnitsyn VG; Esser ES; Taherbhai MT; Prausnitz MR; Compans RW; Skountzou I -
Gene transfection enhanced by ultrasound exposure combined with drug treatment guided by gene chip analysis.
Int J Hyperthermia Volume: 28 Page(s): 349 - 361
01/01/2012 Authors: Liu Y; Bowen NJ; Matyunina L; McDonald J; Prausnitz MR -
Delivery systems for intradermal vaccination.
Curr Top Microbiol Immunol Volume: 351 Page(s): 77 - 112
01/01/2012 Authors: Kim YC; Jarrahian C; Zehrung D; Mitragotri S; Prausnitz MR -
A Research on the Investment Pattern between Real-Estate and Stock Market in South Korea: Using the Granger-causality Test
Volume: 342 Page(s): 77 - +
01/01/2012 Authors: Kim Y; Yi Y-K -
Recovery of skin barrier after stratum corneum removal by microdermabrasion.
AAPS PharmSciTech Volume: 12 Page(s): 1393 - 1400
12/01/2011 Authors: Andrews S; Lee JW; Prausnitz M -
Infusion pressure and pain during microneedle injection into skin of human subjects.
Biomaterials Volume: 32 Page(s): 6823 - 6831
10/01/2011 Authors: Gupta J; Park SS; Bondy B; Felner EI; Prausnitz MR -
Kinetics of skin resealing after insertion of microneedles in human subjects.
J Control Release Volume: 154 Page(s): 148 - 155
09/05/2011 Authors: Gupta J; Gill HS; Andrews SN; Prausnitz MR -
Local transdermal delivery of phenylephrine to the anal sphincter muscle using microneedles.
J Control Release Volume: 154 Page(s): 138 - 147
09/05/2011 Authors: Baek C; Han M; Min J; Prausnitz MR; Park J-H; Park JH -
Transdermal insulin delivery using microdermabrasion.
Pharm Res Volume: 28 Page(s): 2110 - 2118
09/01/2011 Authors: Andrews S; Lee JW; Choi S-O; Prausnitz MR -
Microsecond thermal ablation of skin for transdermal drug delivery.
J Control Release Volume: 154 Page(s): 58 - 68
08/25/2011 Authors: Lee JW; Gadiraju P; Park J-H; Allen MG; Prausnitz MR -
Serological memory and long-term protection to novel H1N1 influenza virus after skin vaccination.
J Infect Dis Volume: 204 Page(s): 582 - 591
08/15/2011 Authors: Koutsonanos DG; del Pilar Martin M; Zarnitsyn VG; Jacob J; Prausnitz MR; Compans RW; Skountzou I -
The rule of five for non-oral routes of drug delivery: ophthalmic, inhalation and transdermal.
Pharm Res Volume: 28 Page(s): 943 - 948
05/01/2011 Authors: Choy YB; Prausnitz MR -
Optimization of microdermabrasion for controlled removal of stratum corneum.
Int J Pharm Volume: 407 Page(s): 95 - 104
04/04/2011 Authors: Andrews SN; Zarnitsyn V; Bondy B; Prausnitz MR -
Rapid pharmacokinetics of intradermal insulin administered using microneedles in type 1 diabetes subjects.
Diabetes Technol Ther Volume: 13 Page(s): 451 - 456
04/01/2011 Authors: Gupta J; Felner EI; Prausnitz MR -
Microneedle vaccination with stabilized recombinant influenza virus hemagglutinin induces improved protective immunity.
Clin Vaccine Immunol Volume: 18 Page(s): 647 - 654
04/01/2011 Authors: Weldon WC; Martin MP; Zarnitsyn V; Wang B; Koutsonanos D; Skountzou I; Prausnitz MR; Compans RW -
Mucoadhesive microparticles in a rapidly dissolving tablet for sustained drug delivery to the eye.
Invest Ophthalmol Vis Sci Volume: 52 Page(s): 2627 - 2633
04/01/2011 Authors: Choy YB; Patel SR; Park J-H; McCarey BE; Edelhauser HF; Prausnitz MR -
Visualization of functional nucleic acid delivery to mouse and human epidermis
Volume: 131 Page(s): S69 - S69
04/01/2011 Authors: Gonzalez-Gonzalez E; Kim Y; Speacker TJ; Hickerson RP; Spitler R; Birchall J; Lara M; Hu R; Liang Y; Kirkiles-Smith N -
Bacillus Calmette-Gurin vaccination using a microneedle patch.
Vaccine Volume: 29 Page(s): 2626 - 2636
03/21/2011 Authors: Hiraishi Y; Nandakumar S; Choi S-O; Lee JW; Kim Y-C; Posey JE; Sable SB; Prausnitz MR -
Dissolving microneedle patch for transdermal delivery of human growth hormone.
Small Volume: 7 Page(s): 531 - 539
02/18/2011 Authors: Lee JW; Choi S-O; Felner EI; Prausnitz MR -
Separable arrowhead microneedles.
J Control Release Volume: 149 Page(s): 242 - 249
02/10/2011 Authors: Chu LY; Prausnitz MR -
Enabling skin vaccination using new delivery technologies.
Drug Deliv Transl Res Volume: 1 Page(s): 7 - 12
02/01/2011 Authors: Kim Y-C; Prausnitz MR -
Stability kinetics of influenza vaccine coated onto microneedles during drying and storage.
Pharm Res Volume: 28 Page(s): 135 - 144
01/01/2011 Authors: Kim Y-C; Quan F-S; Compans RW; Kang S-M; Prausnitz MR -
Visualization of plasmid delivery to keratinocytes in mouse and human epidermis.
Sci Rep Volume: 1 Page(s): 158
01/01/2011 Authors: Gonzlez-Gonzlez E; Kim Y-C; Speaker TJ; Hickerson RP; Spitler R; Birchall JC; Lara MF; Hu R-H; Liang Y; Kirkiles-Smith N -
Suprachoroidal drug delivery to the back of the eye using hollow microneedles.
Pharm Res Volume: 28 Page(s): 166 - 176
01/01/2011 Authors: Patel SR; Lin ASP; Edelhauser HF; Prausnitz MR -
Immune stimulation following microneedle delivery of influenza virus-like particle (VLP) vaccines to human skin
Volume: 15 Page(s): 1111 - 1111
12/01/2010 Authors: Pearton M; Kang S-M; Song J-M; Kim Y-C; Quan F-S; Ivory M; Prausnitz MR; Compans RW; Birchall JC -
Layer-by-layer assembly of DNA- and protein-containing films on microneedles for drug delivery to the skin.
Biomacromolecules Volume: 11 Page(s): 3136 - 3143
11/08/2010 Authors: Saurer EM; Flessner RM; Sullivan SP; Prausnitz MR; Lynn DM -
Dose sparing enabled by skin immunization with influenza virus-like particle vaccine using microneedles.
J Control Release Volume: 147 Page(s): 326 - 332
11/01/2010 Authors: Quan F-S; Kim Y-C; Compans RW; Prausnitz MR; Kang S-M -
Improved protection against avian influenza H5N1 virus by a single vaccination with virus-like particles in skin using microneedles.
Antiviral Res Volume: 88 Page(s): 244 - 247
11/01/2010 Authors: Song J-M; Kim Y-C; Barlow PG; Hossain MJ; Park K-M; Donis RO; Prausnitz MR; Compans RW; Kang S-M -
Transdermal delivery enhanced by antimicrobial peptides.
J Biomed Nanotechnol Volume: 6 Page(s): 612 - 620
10/01/2010 Authors: Kim Y-C; Ludovice PJ; Prausnitz MR -
Fabrication of dissolving polymer microneedles for controlled drug encapsulation and delivery: Bubble and pedestal microneedle designs.
J Pharm Sci Volume: 99 Page(s): 4228 - 4238
10/01/2010 Authors: Chu LY; Choi S-O; Prausnitz MR -
A microneedle roller for transdermal drug delivery.
Eur J Pharm Biopharm Volume: 76 Page(s): 282 - 289
10/01/2010 Authors: Park J-H; Choi S-O; Seo S; Choy YB; Prausnitz MR -
Three Generations of Transdermal Drug Delivery
EXPERIMENTAL DERMATOLOGY Volume: 19 Page(s): 950 - 951
10/01/2010 Authors: Prausnitz MR -
Microneedle delivery of H5N1 influenza virus-like particles to the skin induces long-lasting B- and T-cell responses in mice.
Clin Vaccine Immunol Volume: 17 Page(s): 1381 - 1389
09/01/2010 Authors: Song J-M; Kim Y-C; Lipatov AS; Pearton M; Davis CT; Yoo D-G; Park K-M; Chen L-M; Quan F-S; Birchall JC -
Formulation of microneedles coated with influenza virus-like particle vaccine.
AAPS PharmSciTech Volume: 11 Page(s): 1193 - 1201
09/01/2010 Authors: Kim Y-C; Quan F-S; Compans RW; Kang S-M; Prausnitz MR -
Ultrasound-enhanced drug transport and distribution in the brain.
AAPS PharmSciTech Volume: 11 Page(s): 1005 - 1017
09/01/2010 Authors: Liu Y; Paliwal S; Bankiewicz KS; Bringas JR; Heart G; Mitragotri S; Prausnitz MR -
Influenza virus-like particles coated onto microneedles can elicit stimulatory effects on Langerhans cells in human skin.
Vaccine Volume: 28 Page(s): 6104 - 6113
08/23/2010 Authors: Pearton M; Kang S-M; Song J-M; Kim Y-C; Quan F-S; Anstey A; Ivory M; Prausnitz MR; Compans RW; Birchall JC -
Intradermal vaccination with influenza virus-like particles by using microneedles induces protection superior to that with intramuscular immunization.
J Virol Volume: 84 Page(s): 7760 - 7769
08/01/2010 Authors: Quan F-S; Kim Y-C; Vunnava A; Yoo D-G; Song J-M; Prausnitz MR; Compans RW; Kang S-M -
Dissolving polymer microneedle patches for influenza vaccination.
Nat Med Volume: 16 Page(s): 915 - 920
08/01/2010 Authors: Sullivan SP; Koutsonanos DG; Del Pilar Martin M; Lee JW; Zarnitsyn V; Choi S-O; Murthy N; Compans RW; Skountzou I; Prausnitz MR -
Delivery of molecules into cells using carbon nanoparticles activated by femtosecond laser pulses.
Nat Nanotechnol Volume: 5 Page(s): 607 - 611
08/01/2010 Authors: Chakravarty P; Qian W; El-Sayed MA; Prausnitz MR -
Transdermal delivery of naltrexol and skin permeability lifetime after microneedle treatment in hairless guinea pigs.
J Pharm Sci Volume: 99 Page(s): 3072 - 3080
07/01/2010 Authors: Banks SL; Pinninti RR; Gill HS; Paudel KS; Crooks PA; Brogden NK; Prausnitz MR; Stinchcomb AL -
Saving cells from ultrasound-induced apoptosis: quantification of cell death and uptake following sonication and effects of targeted calcium chelation.
Ultrasound Med Biol Volume: 36 Page(s): 1008 - 1021
06/01/2010 Authors: Hutcheson JD; Schlicher RK; Hicks HK; Prausnitz MR -
Cutaneous vaccination using microneedles coated with hepatitis C DNA vaccine.
Gene Ther Volume: 17 Page(s): 811 - 814
06/01/2010 Authors: Gill HS; Sderholm J; Prausnitz MR; Sllberg M -
Analysis of Mechanical Failure of Polymer Microneedles by Axial Force.
J Korean Phys Soc Volume: 56 Page(s): 1223 - 1227
04/01/2010 Authors: Park J-H; Prausnitz MR -
Changes in cell morphology due to plasma membrane wounding by acoustic cavitation.
Ultrasound Med Biol Volume: 36 Page(s): 677 - 692
04/01/2010 Authors: Schlicher RK; Hutcheson JD; Radhakrishna H; Apkarian RP; Prausnitz MR -
An electrically active microneedle array for electroporation.
Biomed Microdevices Volume: 12 Page(s): 263 - 273
04/01/2010 Authors: Choi S-O; Kim YC; Park J-H; Hutcheson J; Gill HS; Yoon Y-K; Prausnitz MR; Allen MG -
Tracing of Suprachoroidally Microneedle Injected Labeled Drugs and Microbeads in Human, Pig and Rabbit Tissue Using Liquid Nitrogen Snap-Freeze Thaw and Lypholization Techniques
Volume: 51
04/01/2010 Authors: Berglin LC; Bergman L; Patel SR; Berezovsky DE; Myles B; Grossniklaus HE; Laties AM; McCarey BE; Prausnitz MR; Edelhauser HF -
Formulation and coating of microneedles with inactivated influenza virus to improve vaccine stability and immunogenicity.
J Control Release Volume: 142 Page(s): 187 - 195
03/03/2010 Authors: Kim Y-C; Quan F-S; Compans RW; Kang S-M; Prausnitz MR -
Enhanced memory responses to seasonal H1N1 influenza vaccination of the skin with the use of vaccine-coated microneedles.
J Infect Dis Volume: 201 Page(s): 190 - 198
01/15/2010 Authors: Kim Y-C; Quan F-S; Yoo D-G; Compans RW; Kang S-M; Prausnitz MR -
Influenza immunization with trehalose-stabilized virus-like particle vaccine using microneedles.
Procedia Vaccinol Volume: 2 Page(s): 15 - 19
01/01/2010 Authors: Kim Y-C; Quan F-S; Song J-M; Vunnava A; Yoo D-G; Park K-M; Compans RW; Kang S-M; Prausnitz MR -
Improved influenza vaccination in the skin using vaccine coated microneedles.
Vaccine Volume: 27 Page(s): 6932 - 6938
11/16/2009 Authors: Kim Y-C; Quan F-S; Yoo D-G; Compans RW; Kang S-M; Prausnitz MR -
Poly[di(carboxylatophenoxy)phosphazene] is a potent adjuvant for intradermal immunization.
Proc Natl Acad Sci U S A Volume: 106 Page(s): 18936 - 18941
11/10/2009 Authors: Andrianov AK; DeCollibus DP; Gillis HA; Kha HH; Marin A; Prausnitz MR; Babiuk LA; Townsend H; Mutwiri G -
Stabilization of influenza vaccine enhances protection by microneedle delivery in the mouse skin.
PLoS One Volume: 4 Page(s): e7152
09/25/2009 Authors: Quan F-S; Kim Y-C; Yoo D-G; Compans RW; Prausnitz MR; Kang S-M -
Selective removal of stratum corneum by microdermabrasion to increase skin permeability.
Eur J Pharm Sci Volume: 38 Page(s): 95 - 103
09/10/2009 Authors: Gill HS; Andrews SN; Sakthivel SK; Fedanov A; Williams IR; Garber DA; Priddy FH; Yellin S; Feinberg MB; Staprans SI -
BIOT 283-Targeted delivery to the skin and the eye using microneedles
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Volume: 238
08/16/2009 Authors: Prausnitz MR -
Recovery of skin barrier properties after sonication in human subjects.
Ultrasound Med Biol Volume: 35 Page(s): 1405 - 1408
08/01/2009 Authors: Gupta J; Prausnitz MR -
Minimally invasive insulin delivery in subjects with type 1 diabetes using hollow microneedles.
Diabetes Technol Ther Volume: 11 Page(s): 329 - 337
06/01/2009 Authors: Gupta J; Felner EI; Prausnitz MR -
Immunization by vaccine-coated microneedle arrays protects against lethal influenza virus challenge.
Proc Natl Acad Sci U S A Volume: 106 Page(s): 7968 - 7973
05/12/2009 Authors: Zhu Q; Zarnitsyn VG; Ye L; Wen Z; Gao Y; Pan L; Skountzou I; Gill HS; Prausnitz MR; Yang C -
Intrascleral drug delivery to the eye using hollow microneedles.
Pharm Res Volume: 26 Page(s): 395 - 403
02/01/2009 Authors: Jiang J; Moore JS; Edelhauser HF; Prausnitz MR -
Transdermal influenza immunization with vaccine-coated microneedle arrays.
PLoS One Volume: 4 Page(s): e4773
01/01/2009 Authors: Koutsonanos DG; del Pilar Martin M; Zarnitsyn VG; Sullivan SP; Compans RW; Prausnitz MR; Skountzou I -
Microneedle-based vaccines.
Curr Top Microbiol Immunol Volume: 333 Page(s): 369 - 393
01/01/2009 Authors: Prausnitz MR; Mikszta JA; Cormier M; Andrianov AK -
Micro-scale devices for transdermal drug delivery.
Int J Pharm Volume: 364 Page(s): 227 - 236
12/08/2008 Authors: Arora A; Prausnitz MR; Mitragotri S -
Transdermal drug delivery.
Nat Biotechnol Volume: 26 Page(s): 1261 - 1268
11/01/2008 Authors: Prausnitz MR; Langer R -
Mucoadhesive microdiscs engineered for ophthalmic drug delivery: effect of particle geometry and formulation on preocular residence time.
Invest Ophthalmol Vis Sci Volume: 49 Page(s): 4808 - 4815
11/01/2008 Authors: Choy YB; Park J-H; McCarey BE; Edelhauser HF; Prausnitz MR -
Modeling transmembrane transport through cell membrane wounds created by acoustic cavitation.
Biophys J Volume: 95 Page(s): 4124 - 4138
11/01/2008 Authors: Zarnitsyn V; Rostad CA; Prausnitz MR -
Biochemical enhancement of transdermal delivery with magainin peptide: modification of electrostatic interactions by changing pH.
Int J Pharm Volume: 362 Page(s): 20 - 28
10/01/2008 Authors: Kim Y-C; Late S; Banga AK; Ludovice PJ; Prausnitz MR -
Effect of microneedle design on pain in human volunteers.
Clin J Pain Volume: 24 Page(s): 585 - 594
09/01/2008 Authors: Gill HS; Denson DD; Burris BA; Prausnitz MR -
The effect of heat on skin permeability.
Int J Pharm Volume: 359 Page(s): 94 - 103
07/09/2008 Authors: Park J-H; Lee J-W; Kim Y-C; Prausnitz MR -
Flux across [corrected] microneedle-treated skin is increased by increasing charge of naltrexone and naltrexol in vitro.
Pharm Res Volume: 25 Page(s): 1677 - 1685
07/01/2008 Authors: Banks SL; Pinninti RR; Gill HS; Crooks PA; Prausnitz MR; Stinchcomb AL -
Mucoadhesive Microparticles Engineered for Ophthalmic Drug Delivery.
J Phys Chem Solids Volume: 69 Page(s): 1533 - 1536
05/01/2008 Authors: Bin Choy Y; Park J-H; Prausnitz MR -
Pocketed Microneedles for Drug Delivery to the Skin.
J Phys Chem Solids Volume: 69 Page(s): 1537 - 1541
05/01/2008 Authors: Gill HS; Prausnitz MR -
Optimization of transdermal delivery using magainin pore-forming peptide.
J Phys Chem Solids Volume: 69 Page(s): 1560 - 1563
05/01/2008 Authors: Kim Y-C; Ludovice PJ; Prausnitz MR -
Dissolving microneedles for transdermal drug delivery.
Biomaterials Volume: 29 Page(s): 2113 - 2124
05/01/2008 Authors: Lee JW; Park J-H; Prausnitz MR -
Synergistic enhancement of skin permeability by N-lauroylsarcosine and ethanol.
Int J Pharm Volume: 352 Page(s): 129 - 138
03/20/2008 Authors: Kim Y-C; Park J-H; Ludovice PJ; Prausnitz MR -
Minimally invasive protein delivery with rapidly dissolving polymer microneedles.
Adv Mater Volume: 20 Page(s): 933 - 938
03/01/2008 Authors: Sullivan SP; Murthy N; Prausnitz MR -
Shear-induced intracellular loading of cells with molecules by controlled microfluidics.
Biotechnol Bioeng Volume: 99 Page(s): 846 - 854
03/01/2008 Authors: Hallow DM; Seeger RA; Kamaev PP; Prado GR; LaPlaca MC; Prausnitz MR -
Microneedles permit transdermal delivery of a skin-impermeant medication to humans.
Proc Natl Acad Sci U S A Volume: 105 Page(s): 2058 - 2063
02/12/2008 Authors: Wermeling DP; Banks SL; Hudson DA; Gill HS; Gupta J; Prausnitz MR; Stinchcomb AL -
Influence of the cell wall on intracellular delivery to algal cells by electroporation and sonication.
Ultrasound Med Biol Volume: 33 Page(s): 1805 - 1817
11/01/2007 Authors: Azencott HR; Peter GF; Prausnitz MR -
Transdermal delivery enhanced by magainin pore-forming peptide.
J Control Release Volume: 122 Page(s): 375 - 383
10/08/2007 Authors: Kim Y-C; Ludovice PJ; Prausnitz MR -
Ultrasound-enhanced chemotherapy and gene delivery for glioma cells.
Technol Cancer Res Treat Volume: 6 Page(s): 433 - 442
10/01/2007 Authors: Zarnitsyn VG; Kamaev PP; Prausnitz MR -
Does needle size matter?
J Diabetes Sci Technol Volume: 1 Page(s): 725 - 729
09/01/2007 Authors: Gill HS; Prausnitz MR -
Coated microneedles for drug delivery to the eye.
Invest Ophthalmol Vis Sci Volume: 48 Page(s): 4038 - 4043
09/01/2007 Authors: Jiang J; Gill HS; Ghate D; McCarey BE; Patel SR; Edelhauser HF; Prausnitz MR -
Coating formulations for microneedles.
Pharm Res Volume: 24 Page(s): 1369 - 1380
07/01/2007 Authors: Gill HS; Prausnitz MR -
Tapered conical polymer microneedles fabricated using an integrated lens technique for transdermal drug delivery.
IEEE Trans Biomed Eng Volume: 54 Page(s): 903 - 913
05/01/2007 Authors: Park J-H; Yoon Y-K; Choi S-O; Prausnitz MR; Allen MG -
Ultrasonically targeted delivery into endothelial and smooth muscle cells in ex vivo arteries.
J Control Release Volume: 118 Page(s): 285 - 293
04/23/2007 Authors: Hallow DM; Mahajan AD; Prausnitz MR -
Future directions for therapeutic ultrasound.
Ultrasound Med Biol Volume: 33 Page(s): 657
04/01/2007 Authors: Campbell P; Prausnitz MR -
Polymer particle-based micromolding to fabricate novel microstructures.
Biomed Microdevices Volume: 9 Page(s): 223 - 234
04/01/2007 Authors: Park J-H; Choi S-O; Kamath R; Yoon Y-K; Allen MG; Prausnitz MR -
Synergistic effect of ultrasound and PEI on DNA transfection in vitro.
J Control Release Volume: 118 Page(s): 126 - 135
03/12/2007 Authors: Deshpande MC; Prausnitz MR -
Coated microneedles for transdermal delivery.
J Control Release Volume: 117 Page(s): 227 - 237
02/12/2007 Authors: Gill HS; Prausnitz MR -
Micro-ablation of skin by arc-discharge jet ejection for transdermal drug delivery
01/01/2007 Authors: Gadiraju PD; Park J-H; Lee JW; Prausnitz MR; Allen MG -
Measurement and correlation of acoustic cavitation with cellular bioeffects.
Ultrasound Med Biol Volume: 32 Page(s): 1111 - 1122
07/01/2006 Authors: Hallow DM; Mahajan AD; McCutchen TE; Prausnitz MR -
Measurement and prediction of lateral diffusion within human sclera.
Invest Ophthalmol Vis Sci Volume: 47 Page(s): 3011 - 3016
07/01/2006 Authors: Jiang J; Geroski DH; Edelhauser HF; Prausnitz MR -
Plasmid DNA and siRNA transfection of intestinal epithelial monolayers by electroporation.
Int J Pharm Volume: 315 Page(s): 122 - 133
06/06/2006 Authors: Ghartey-Tagoe EB; Babbin BA; Nusrat A; Neish AS; Prausnitz MR -
Mechanism of intracellular delivery by acoustic cavitation.
Ultrasound Med Biol Volume: 32 Page(s): 915 - 924
06/01/2006 Authors: Schlicher RK; Radhakrishna H; Tolentino TP; Apkarian RP; Zarnitsyn V; Prausnitz MR -
Mechanism of fluid infusion during microneedle insertion and retraction.
J Control Release Volume: 112 Page(s): 357 - 361
05/30/2006 Authors: Martanto W; Moore JS; Couse T; Prausnitz MR -
Polymer microneedles for controlled-release drug delivery.
Pharm Res Volume: 23 Page(s): 1008 - 1019
05/01/2006 Authors: Park J-H; Allen MG; Prausnitz MR -
Precise microinjection into skin using hollow microneedles.
J Invest Dermatol Volume: 126 Page(s): 1080 - 1087
05/01/2006 Authors: Wang PM; Cornwell M; Hill J; Prausnitz MR -
A peptide chaperone for transdermal drug delivery.
Nat Biotechnol Volume: 24 Page(s): 416 - 417
04/01/2006 Authors: Prausnitz MR -
Assessment of trueness of a glucose monitor using interstitial fluid and whole blood as specimen matrix.
Diabetes Technol Ther Volume: 8 Page(s): 76 - 80
02/01/2006 Authors: Vesper HW; Wang PM; Archibold E; Prausnitz MR; Myers GL -
Microinfusion using hollow microneedles.
Pharm Res Volume: 23 Page(s): 104 - 113
01/01/2006 Authors: Martanto W; Moore JS; Kashlan O; Kamath R; Wang PM; O'Neal JM; Prausnitz MR -
Mechanism of intracellular delivery by ultrasound
Volume: 230 Page(s): U1219 - U1219
08/28/2005 Authors: Prausnitz MR; Schlicher RK; Radhakrishna H; Tolentino TP; Apkarian RP; Zarnitsyn V -
Biodegradable polymer microneedles: fabrication, mechanics and transdermal drug delivery.
J Control Release Volume: 104 Page(s): 51 - 66
05/05/2005 Authors: Park J-H; Allen MG; Prausnitz MR -
Hollow metal microneedles for insulin delivery to diabetic rats.
IEEE Trans Biomed Eng Volume: 52 Page(s): 909 - 915
05/01/2005 Authors: Davis SP; Martanto W; Allen MG; Prausnitz MR -
Increased permeability of intestinal epithelial monolayers mediated by electroporation.
J Control Release Volume: 103 Page(s): 177 - 190
03/02/2005 Authors: Ghartey-Tagoe EB; Morgan JS; Neish AS; Prausnitz MR -
Minimally invasive extraction of dermal interstitial fluid for glucose monitoring using microneedles.
Diabetes Technol Ther Volume: 7 Page(s): 131 - 141
02/01/2005 Authors: Wang PM; Cornwell M; Prausnitz MR -
Measurement and prediction of lateral diffusion within human sclera
Volume: 46
01/01/2005 Authors: Jiang N; Prausnitz M; Edelhauser H; Geroski D -
Model of transient drug diffusion across cornea.
J Control Release Volume: 99 Page(s): 241 - 258
09/30/2004 Authors: Zhang W; Prausnitz MR; Edwards A -
Insertion of microneedles into skin: measurement and prediction of insertion force and needle fracture force.
J Biomech Volume: 37 Page(s): 1155 - 1163
08/01/2004 Authors: Davis SP; Landis BJ; Adams ZH; Allen MG; Prausnitz MR -
Transdermal delivery of insulin using microneedles in vivo.
Pharm Res Volume: 21 Page(s): 947 - 952
06/01/2004 Authors: Martanto W; Davis SP; Holiday NR; Wang J; Gill HS; Prausnitz MR -
Tissue electroporation: quantification and analysis of heterogeneous transport in multicellular environments.
Biophys J Volume: 86 Page(s): 3260 - 3268
05/01/2004 Authors: Canatella PJ; Black MM; Bonnichsen DM; McKenna C; Prausnitz MR -
Physical parameters influencing optimization of ultrasound-mediated DNA transfection.
Ultrasound Med Biol Volume: 30 Page(s): 527 - 538
04/01/2004 Authors: Zarnitsyn VG; Prausnitz MR -
Quantification of optison bubble size and lifetime during sonication dominant role of secondary cavitation bubbles causing acoustic bioeffects.
J Acoust Soc Am Volume: 115 Page(s): 1818 - 1825
04/01/2004 Authors: Kamaev PP; Hutcheson JD; Wilson ML; Prausnitz MR -
Microneedles for transdermal drug delivery.
Adv Drug Deliv Rev Volume: 56 Page(s): 581 - 587
03/27/2004 Authors: Prausnitz MR -
Drug delivery through the sclera: effects of thickness, hydration, and sustained release systems.
Exp Eye Res Volume: 78 Page(s): 599 - 607
03/01/2004 Authors: Lee S-B; Geroski DH; Prausnitz MR; Edelhauser HF -
Electroporation-mediated delivery of molecules to model intestinal epithelia.
Int J Pharm Volume: 270 Page(s): 127 - 138
02/11/2004 Authors: Ghartey-Tagoe EB; Morgan JS; Ahmed K; Neish AS; Prausnitz MR -
Current status and future potential of transdermal drug delivery.
Nat Rev Drug Discov Volume: 3 Page(s): 115 - 124
02/01/2004 Authors: Prausnitz MR; Mitragotri S; Langer R -
Biodegradable polymer microneedles: fabrication, mechanics and transdermal drug delivery.
Conf Proc IEEE Eng Med Biol Soc Volume: 2004 Page(s): 2654 - 2657
01/01/2004 Authors: Park J-H; Allen MG; Prausnitz MR -
Prediction of ultrasound-mediated disruption of cell membranes using machine learning techniques and statistical analysis of acoustic spectra.
IEEE Trans Biomed Eng Volume: 51 Page(s): 82 - 89
01/01/2004 Authors: Lee EK; Gallagher RJ; Campbell AM; Prausnitz MR -
Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: fabrication methods and transport studies.
Proc Natl Acad Sci U S A Volume: 100 Page(s): 13755 - 13760
11/25/2003 Authors: McAllister DV; Wang PM; Davis SP; Park J-H; Canatella PJ; Allen MG; Prausnitz MR -
Bioeffects caused by changes in acoustic cavitation bubble density and cell concentration: a unified explanation based on cell-to-bubble ratio and blast radius.
Ultrasound Med Biol Volume: 29 Page(s): 1211 - 1222
08/01/2003 Authors: Guzmn HR; McNamara AJ; Nguyen DX; Prausnitz MR -
Quantification of skin shrinkage after excision
Volume: 17 Page(s): A789 - A789
03/17/2003 Authors: Wang PM; Cornwell M; Prausnitz MR -
Microneedles for transdermal delivery of insulin and extraction of interstitial fluid for glucose monitoring
Volume: 17 Page(s): A556 - A556
03/14/2003 Authors: Wang PM; Cornwell M; Prausnitz MR -
Gene packaging with lipids, peptides and viruses inhibits transfection by electroporation in vitro.
J Control Release Volume: 86 Page(s): 361 - 370
01/17/2003 Authors: Coulberson AL; Hud NV; LeDoux JM; Vilfan ID; Prausnitz MR -
Equilibrium loading of cells with macromolecules by ultrasound: effects of molecular size and acoustic energy.
J Pharm Sci Volume: 91 Page(s): 1693 - 1701
07/01/2002 Authors: Guzmn HR; Nguyen DX; McNamara AJ; Prausnitz MR -
Intracellular drug delivery using low-frequency ultrasound: quantification of molecular uptake and cell viability.
Pharm Res Volume: 18 Page(s): 1514 - 1520
11/01/2001 Authors: Keyhani K; Guzmn HR; Parsons A; Lewis TN; Prausnitz MR -
Predicted permeability of the cornea to topical drugs.
Pharm Res Volume: 18 Page(s): 1497 - 1508
11/01/2001 Authors: Edward A; Prausnitz MR -
Prediction and optimization of gene transfection and drug delivery by electroporation.
Gene Ther Volume: 8 Page(s): 1464 - 1469
10/01/2001 Authors: Canatella PJ; Prausnitz MR -
Ultrasound-mediated disruption of cell membranes. II. Heterogeneous effects on cells.
J Acoust Soc Am Volume: 110 Page(s): 597 - 606
07/01/2001 Authors: Guzmn HR; Nguyen DX; Khan S; Prausnitz MR -
Ultrasound-mediated disruption of cell membranes. I. Quantification of molecular uptake and cell viability.
J Acoust Soc Am Volume: 110 Page(s): 588 - 596
07/01/2001 Authors: Guzmn HR; Nguyen DX; Khan S; Prausnitz MR -
Sonoluminescence as an indicator of cell membrane disruption by acoustic cavitation.
Ultrasound Med Biol Volume: 27 Page(s): 841 - 850
06/01/2001 Authors: Cochran SA; Prausnitz MR -
Magainin-mediated disruption of stratum corneum lipid vesicles.
Pharm Res Volume: 18 Page(s): 894 - 896
06/01/2001 Authors: Kaushik S; Krishnan A; Prausnitz MR; Ludovice PJ -
Quantitative study of electroporation-mediated molecular uptake and cell viability.
Biophys J Volume: 80 Page(s): 755 - 764
02/01/2001 Authors: Canatella PJ; Karr JF; Petros JA; Prausnitz MR -
Lack of pain associated with microfabricated microneedles.
Anesth Analg Volume: 92 Page(s): 502 - 504
02/01/2001 Authors: Kaushik S; Hord AH; Denson DD; McAllister DV; Smitra S; Allen MG; Prausnitz MR -
Overcoming skin's barrier: the search for effective and user-friendly drug delivery.
Diabetes Technol Ther Volume: 3 Page(s): 233 - 236
01/01/2001 Authors: Prausnitz MR -
Drug delivery by electrical, ultrasonic, and microneedle disruption of biological barriers.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Volume: 219 Page(s): U34 - U34
03/26/2000 Authors: Prausnitz MR -
Microfabricated microneedles for gene and drug delivery.
Annu Rev Biomed Eng Volume: 2 Page(s): 289 - 313
01/01/2000 Authors: McAllister DV; Allen MG; Prausnitz MR -
Electrical impedance spectroscopy for rapid and noninvasive analysis of skin electroporation.
Methods Mol Med Volume: 37 Page(s): 377 - 406
01/01/2000 Authors: Pliquett U; Prausnitz MR -
Mechanistic studies of skin electroporation using biophysical methods.
Methods Mol Med Volume: 37 Page(s): 213 - 245
01/01/2000 Authors: Prausnitz MR; Pliquett U; Vanbever R -
The effect of intraocular pressure on human and rabbit scleral permeability.
Invest Ophthalmol Vis Sci Volume: 40 Page(s): 3054 - 3058
11/01/1999 Authors: Rudnick DE; Noonan JS; Geroski DH; Prausnitz MR; Edelhauser HF -
Microfabricated microneedles: A novel approach to transdermal drug delivery.
J Pharm Sci Volume: 88 Page(s): 948
09/01/1999 Authors: Henry S; McAllister DV; Allen MG; Prausnitz MR -
Drug delivery through the sclera: The influence of thickness, hydration, and sustained release systems
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 40 Page(s): S83 - S83
03/15/1999 Authors: Lee SB; Noonan JS; Geroski DH; Prausnitz MR; Edelhauser HF -
A practical assessment of transdermal drug delivery by skin electroporation.
Adv Drug Deliv Rev Volume: 35 Page(s): 61 - 76
01/04/1999 Authors: Prausnitz MR -
Enhanced drug delivery using high-voltage pulses
ADVANCED DRUG DELIVERY REVIEWS Volume: 35 Page(s): 1 - 2
01/04/1999 Authors: Preat V; Prausnitz MR -
Recent advances in skin electroporation: Mechanism and efficacy
Page(s): 149 - 152
01/01/1999 Authors: Weaver JC; Pliquett UF; Zewert TE; Vanbever R; Herndon TO; Gowrishankar TR; Chen T; Prausnitz MR; Vaughan TE; Chizmadzhev Y -
The effects of pulsed electrical protocols on skin damage, sensation, and pain
Page(s): 915 - 918
01/01/1999 Authors: Prausnitz MR -
Macromolecules as novel transdermal transport enhancers for skin electroporation
Page(s): 903 - 906
01/01/1999 Authors: Vanbever R; Prausnitz MR; Preat V -
Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye.
J Pharm Sci Volume: 87 Page(s): 1479 - 1488
12/01/1998 Authors: Prausnitz MR; Noonan JS -
Assessing the potential of skin electroporation for the delivery of protein- and gene-based drugs.
Trends Biotechnol Volume: 16 Page(s): 408 - 412
10/01/1998 Authors: Banga AK; Prausnitz MR -
Microfabricated microneedles: a novel approach to transdermal drug delivery.
J Pharm Sci Volume: 87 Page(s): 922 - 925
08/01/1998 Authors: Henry S; McAllister DV; Allen MG; Prausnitz MR -
Non-invasive assessment and control of ultrasound-mediated membrane permeabilization.
Pharm Res Volume: 15 Page(s): 918 - 924
06/01/1998 Authors: Liu J; Lewis TN; Prausnitz MR -
Heparin alters transdermal transport associated with electroporation.
Biochem Biophys Res Commun Volume: 234 Page(s): 637 - 640
05/29/1997 Authors: Weaver JC; Vanbever R; Vaughan TE; Prausnitz MR -
Macromolecules as novel transdermal transport enhancers for skin electroporation.
Pharm Res Volume: 14 Page(s): 638 - 644
05/01/1997 Authors: Vanbever R; Prausnitz MR; Prat V -
Reversible skin permeabilization for transdermal delivery of macromolecules.
Crit Rev Ther Drug Carrier Syst Volume: 14 Page(s): 455 - 483
01/01/1997 Authors: Prausnitz MR -
Imaging regions of transport across human stratum corneum during high-voltage and low-voltage exposures.
J Pharm Sci Volume: 85 Page(s): 1363 - 1370
12/01/1996 Authors: Prausnitz MR; Gimm JA; Guy RH; Langer R; Weaver JC; Cullander C -
Transdermal delivery of heparin by skin electroporation.
Biotechnology (N Y) Volume: 13 Page(s): 1205 - 1209
11/01/1995 Authors: Prausnitz MR; Edelman ER; Gimm JA; Langer R; Weaver JC -
MEASUREMENT OF RAPID RELEASE KINETICS FOR DRUG-DELIVERY (VOL 12, PG 549, 1995)
PHARMACEUTICAL RESEARCH Volume: 12 Page(s): 1244 - 1244
08/01/1995 Authors: PLIQUETT U; PRAUSNITZ MR; CHIZMADZHEV YA; WEAVER JC -
Millisecond measurement of transport during and after an electroporation pulse.
Biophys J Volume: 68 Page(s): 1864 - 1870
05/01/1995 Authors: Prausnitz MR; Corbett JD; Gimm JA; Golan DE; Langer R; Weaver JC -
Measurement of rapid release kinetics for drug delivery.
Pharm Res Volume: 12 Page(s): 549 - 555
04/01/1995 Authors: Pliquett U; Prausnitz MR; Chizmadzhev YA; Weaver JC -
Focus on: ORBIS International Flying Eye Hospital, Department of Technical Services.
J Clin Eng Volume: 20 Page(s): 388 - 393
01/01/1995 Authors: Prausnitz MR; Cordero I; Levenson A -
Rapid temporal control of transdermal drug delivery by electroporation.
Pharm Res Volume: 11 Page(s): 1834 - 1837
12/01/1994 Authors: Prausnitz MR; Pliquett U; Langer R; Weaver JC -
Quantitative study of molecular transport due to electroporation: uptake of bovine serum albumin by erythrocyte ghosts.
Biophys J Volume: 66 Page(s): 1522 - 1530
05/01/1994 Authors: Prausnitz MR; Milano CD; Gimm JA; Langer R; Weaver JC -
Electroporation of mammalian skin: a mechanism to enhance transdermal drug delivery.
Proc Natl Acad Sci U S A Volume: 90 Page(s): 10504 - 10508
11/15/1993 Authors: Prausnitz MR; Bose VG; Langer R; Weaver JC -
A quantitative study of electroporation showing a plateau in net molecular transport.
Biophys J Volume: 65 Page(s): 414 - 422
07/01/1993 Authors: Prausnitz MR; Lau BS; Milano CD; Conner S; Langer R; Weaver JC -
TRANSTISSUE MOLECULAR-TRANSPORT DUE TO ELECTROPORATION OF SKIN
Page(s): 122 - 124
01/01/1993 Authors: PRAUSNITZ MR; BOSE VG; LANGER RS; WEAVER JC -
QUANTITATIVE-DETERMINATION OF MOLECULAR-TRANSPORT ACROSS ERYTHROCYTE GHOST MEMBRANES BY ELECTROPORATION
Page(s): 141 - 143
01/01/1993 Authors: LAU BS; MILANO CD; PRAUSNITZ MR; LANGER RS; WEAVER JC