Marie-Claude Perreault PhD
- Department of Cell Biology
Associate Professor
-
Emory University
Cell Biology
615 Michael Street
Overview
The goal of our research is to elucidate the circuit principles and cellular mechanisms that allow subcortical (brainstem) descending pathways to control motor and autonomic functions. Research questions are addressed using multiple approaches such as single-cell calcium imaging, electrophysiology, optogenetics, photo-uncaging, and neuroanatomical tract-tracing which we apply to the mouse animal model. Determination of the normal capabilities of the brainstem descending systems should help better understand how functional connections between brainstem neurons and spinal cord neurons can be improved after CNS injury or neurodevelopmental disorders such as autism.
Academic Appointment
- Associate Professor, Cell Biology, Emory School of Medicine
Education
Degrees
- PhD Neurophysiology from University of Montreal
- MSc Neuroanatomy from University of Montreal
- BSc Physics from University of Montreal
Research
Publications
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Editorial: Subcortical and spinal control of motor networks across vertebrates.
Front Neuroanat Volume: 18 Page(s): 1378811
01/01/2024 Authors: Boulland J-L; Perreault M-C -
Excitatory and Inhibitory Descending Commissural Interneurons Differentially Integrate Supraspinal and Segmental Sensory Signals.
J Neurosci Volume: 43 Page(s): 5014 - 5029
07/05/2023 Authors: Giorgi A; Cer AT; Mohan S; Perreault M-C -
Corrigendum to "C Fragment of Tetanus Toxin Hybrid Proteins Evaluated for Muscle-specific Transsynaptic Mapping of Spinal Motor Circuitry in the Newborn Mouse" [Neuroscience 141(2) (2006) 803-816].
Neuroscience Volume: 424 Page(s): 211
01/01/2020 Authors: Perreault M-C; Pastor-Bernier A; Renaud J-S; Roux S; Glover JC -
Crossed activation of thoracic trunk motoneurons by medullary reticulospinal neurons.
J Neurophysiol Volume: 122 Page(s): 2601 - 2613
12/01/2019 Authors: LaPallo BK; Giorgi A; Perreault M-C -
Influence of Brain Stem on Axial and Hindlimb Spinal Locomotor Rhythm Generating Circuits of the Neonatal Mouse.
Front Neurosci Volume: 12 Page(s): 53
01/01/2018 Authors: Jean-Xavier C; Perreault M-C -
Pontine reticulospinal projections in the neonatal mouse: Internal organization and axon trajectories.
J Comp Neurol Volume: 524 Page(s): 1270 - 1291
04/15/2016 Authors: Sivertsen MS; Perreault M-C; Glover JC -
Segmental organization of vestibulospinal inputs to spinal interneurons mediating crossed activation of thoracolumbar motoneurons in the neonatal mouse.
J Neurosci Volume: 35 Page(s): 8158 - 8169
05/27/2015 Authors: Kasumacic N; Lambert FM; Coulon P; Bras H; Vinay L; Perreault M-C; Glover JC -
Organization of pontine reticulospinal inputs to motoneurons controlling axial and limb muscles in the neonatal mouse.
J Neurophysiol Volume: 112 Page(s): 1628 - 1643
10/01/2014 Authors: Sivertsen MS; Glover JC; Perreault M-C -
Glutamatergic reticulospinal neurons in the mouse: developmental origins, axon projections, and functional connectivity.
Ann N Y Acad Sci Volume: 1279 Page(s): 80 - 89
03/01/2013 Authors: Perreault M-C; Glover JC -
Vestibular-mediated synaptic inputs and pathways to sympathetic preganglionic neurons in the neonatal mouse.
J Physiol Volume: 590 Page(s): 5809 - 5826
11/15/2012 Authors: Kasumacic N; Glover JC; Perreault M-C