Publications

• Divergent populations of HIV-infected naive and memory CD4+ T cell clones in children on antiretroviral therapy.
  J Clin Invest Volume: 135
  05/01/2025 Authors: Katusiime MG; Neer V; Guo S; Patro SC; Wang W; Luke B; Capoferri AA; Wu X; Horner AM; Rausch JW
• SIV Env RhmAbs + N-803 at ART initiation prolongs viral decay without disrupting reservoir establishment in SIV-infected infant macaques.
  PLoS Pathog Volume: 21 Page(s): e1012863
  01/01/2025 Authors: Farinre O; Anaya T; King AC; Endrias K; Hbert AH; Hill AL; Jean S; Wood JS; Ehnert S; Liang S
• Impact of the IL-15 superagonist N-803 on latency reversal induced by AZD5582 and on immune cells in ART-suppressed rhesus macaques
  Volume: 52 Page(s): 308 - 309
  10/01/2023 Authors: Dashti A; Sukkestad S; Horner AM; Neja M; Lin A; Schoof N; Singh V; Mavigner M; King H; Mason RD
• Pilot study of a cIAP inhibitor ( AZD5582) + BCL-2 inhibitor (ABT199) in SIV-infected, art-suppressed rhesus macaques
  Volume: 52 Page(s): 333 - 333
  10/01/2023 Authors: Ukhueduan BO; Lopez LL; Bricker K; Schoof N; Singh V; Dashti A; Mavigner M; Schauer A; Tompkin L; Cottrell ML
• AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques.
  Nat Med Volume: 29 Page(s): 2535 - 2546
  10/01/2023 Authors: Dashti A; Sukkestad S; Horner AM; Neja M; Siddiqi Z; Waller C; Goldy J; Monroe D; Lin A; Schoof N
• Treatment with sofosbuvir attenuates the adverse neurodevelopmental consequences of Zika virus infection in infant rhesus macaques.
  J Neuroimmunol Volume: 381 Page(s): 578148
  08/15/2023 Authors: Medina A; Rusnak R; Richardson R; Zimmerman MG; Suthar M; Schoof N; Kovacs-Balint Z; Mavigner M; Sanchez M; Chahroudi A
• Broadly neutralizing antibodies: "The next thing" to treat children with HIV?
  Sci Transl Med Volume: 15 Page(s): eadi0293
  07/05/2023 Authors: Mavigner M; Chahroudi A
• Investigation of Blood Plasma Viral Nucleocapsid Antigen as a Marker of Active Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant Infection.
  Open Forum Infect Dis Volume: 10 Page(s): ofad226
  05/01/2023 Authors: Damhorst GL; Schoof N; Nguyen P-V; Verkerke H; Wilber E; McLendon K; O'Sick W; Baugh T; Cheedarla S; Cheedarla N
• Comparison of Mid-turbinate Nasal Swabs, Saliva, and Nasopharyngeal Swabs for SARS-CoV-2 Reverse Transcription-Polymerase Chain Reaction Testing in Pediatric Outpatients.
  Arch Pathol Lab Med Volume: 146 Page(s): 1056 - 1061
  09/01/2022 Authors: Vos MB; Gonzalez MD; Stone C; Cleeton R; Figueroa J; Jerris R; Park SI; Heilman S; Nayee R; Chahroudi A
• AZD5582 and SIV Env-targeting rhesus monoclonal antibodies (RhmAbs) +/- N-803 in SIV-infected ART-suppressed rhesus macaques
  Volume: 25 Page(s): 7 - 7
  08/01/2022 Authors: Dashti A; Sukkestad S; Horner AM; Neja M; Lin A; Schoof N; Mavigner M; Lifson JD; Falcinelli SD; Sacha J
• Altered Response Pattern following AZD5582 Treatment of SIV-Infected, ART-Suppressed Rhesus Macaque Infants.
  J Virol Volume: 96 Page(s): e0169921
  04/13/2022 Authors: Bricker KM; Obregon-Perko V; Williams B; Oliver D; Uddin F; Neja M; Hopkins L; Dashti A; Jean S; Wood JS
• Single-Amplicon Multiplex Real-Time Reverse Transcription-PCR with Tiled Probes To Detect SARS-CoV-2 spike Mutations Associated with Variants of Concern.
  J Clin Microbiol Volume: 59 Page(s): e0144621
  11/18/2021 Authors: Babiker A; Immergluck K; Stampfer SD; Rao A; Bassit L; Su M; Nguyen V; Stittleburg V; Ingersoll JM; Bradley HL
• The need for new test verification and regulatory support for innovative diagnostics.
  Nat Biotechnol Volume: 39 Page(s): 1060 - 1062
  09/01/2021 Authors: Roback JD; Tyburski EA; Alter D; Asakrah S; Chahroudi A; Esper A; Farmer S; Figueroa J; K Frediani J; D Gonzalez M
• New Latency Reversing Agents for HIV-1 Cure: Insights from Nonhuman Primate Models.
  Viruses Volume: 13
  08/06/2021 Authors: Bricker KM; Chahroudi A; Mavigner M
• Multidisciplinary assessment of the Abbott BinaxNOW SARS-CoV-2 point-of-care antigen test in the context of emerging viral variants and self-administration.
  Sci Rep Volume: 11 Page(s): 14604
  07/16/2021 Authors: Frediani JK; Levy JM; Rao A; Bassit L; Figueroa J; Vos MB; Wood A; Jerris R; Van Leung-Pineda; Gonzalez MD
• Rapid progression is associated with lymphoid follicle dysfunction in SIV-infected infant rhesus macaques.
  PLoS Pathog Volume: 17 Page(s): e1009575
  05/01/2021 Authors: Wood MP; Jones CI; Lippy A; Oliver BG; Walund B; Fancher KA; Fisher BS; Wright PJ; Fuller JT; Murapa P
• The RADx Tech Test Verification Core and the ACME POCT in the Evaluation of COVID-19 Testing Devices: A Model for Progress and Change.
  IEEE Open J Eng Med Biol Volume: 2 Page(s): 142 - 151
  04/28/2021 Authors: Nehl E; Heilman S; Ku D; Gottfried D; Farmer S; Mannino R; Tyburski E; Sullivan J; Suessmith A; Bassit L
• Latency Reversal 2.0: Giving the Immune System a Seat at the Table.
  Curr HIV/AIDS Rep Volume: 18 Page(s): 117 - 127
  04/01/2021 Authors: Singh V; Dashti A; Mavigner M; Chahroudi A
• CD8 lymphocyte depletion enhances the latency reversal activity of the SMAC mimetic AZD5582 in ART-suppressed SIV-infected rhesus macaques.
  J Virol Volume: 95
  03/25/2021 Authors: Mavigner M; Liao LE; Brooks AD; Ke R; Mattingly C; Schoof N; McBrien J; Carnathan D; Liang S; Vanderford TH
• Covid-19 will not "magically disappear": Why access to widespread testing is paramount.
  Am J Hematol Volume: 96 Page(s): 174 - 178
  02/01/2021 Authors: George PE; Stokes CL; Bassit LC; Chahroudi A; Figueroa J; Griffiths MA; Heilman S; Ku DN; Nehl EJ; Leong T
• Simian-Human Immunodeficiency Virus SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques Is Characterized by Elevated SHIV RNA in the Gut and a High Abundance of Intact SHIV DNA in Naive CD4+ T Cells.
  J Virol Volume: 95
  12/22/2020 Authors: Obregon-Perko V; Bricker KM; Mensah G; Uddin F; Kumar MR; Fray EJ; Siliciano RF; Schoof N; Horner A; Mavigner M
• SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques.
  Volume: 94
  10/14/2020 Authors: Dashti A; Waller C; Mavigner M; Schoof N; Bar KJ; Shaw GM; Vanderford TH; Liang S; Lifson JD; Dunham RM
• Rapid progression in SIV-infected infant rhesus macaques is associated with failure to increase CXCL13 during acute infection, B-cell dysfunction and early viral replication
  Volume: 49 Page(s): 227 - 228
  10/01/2020 Authors: Wood M; Jones CI; Fisher B; Lippy A; Oliver BG; Walund B; Fancher K; Murapa P; Fuller JT; Habib J
• Long-term alterations in brain and behavior after postnatal Zika virus infection in infant macaques.
  Nat Commun Volume: 11 Page(s): 2534
  05/21/2020 Authors: Raper J; Kovacs-Balint Z; Mavigner M; Gumber S; Burke MW; Habib J; Mattingly C; Fair D; Earl E; Feczko E
• Correction for Mavigner et al., "Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques".
  J Virol Volume: 94
  03/31/2020 Authors: Mavigner M; Habib J; Deleage C; Rosen E; Mattingly C; Bricker K; Kashuba A; Amblard F; Schinazi RF; Lawson B
• Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells.
  Nature Volume: 578 Page(s): E21
  02/01/2020 Authors: McBrien JB; Mavigner M; Franchitti L; Smith SA; White E; Tharp GK; Walum H; Busman-Sahay K; Aguilera-Sandoval CR; Thayer WO
• Systemic HIV and SIV latency reversal via non-canonical NF-B signalling in vivo.
  Nature Volume: 578 Page(s): 160 - 165
  02/01/2020 Authors: Nixon CC; Mavigner M; Sampey GC; Brooks AD; Spagnuolo RA; Irlbeck DM; Mattingly C; Ho PT; Schoof N; Cammon CG
• Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells.
  Nature Volume: 578 Page(s): 154 - 159
  02/01/2020 Authors: McBrien JB; Mavigner M; Franchitti L; Smith SA; White E; Tharp GK; Walum H; Busman-Sahay K; Aguilera-Sandoval CR; Thayer WO
• Pharmacological Modulation of the Wnt/-Catenin Pathway Inhibits Proliferation and Promotes Differentiation of Long-Lived Memory CD4+ T Cells in Antiretroviral Therapy-Suppressed Simian Immunodeficiency Virus-Infected Macaques.
  J Virol Volume: 94
  12/12/2019 Authors: Mavigner M; Zanoni M; Tharp GK; Habib J; Mattingly CR; Lichterfeld M; Nega MT; Vanderford TH; Bosinger SE; Chahroudi A
• Postnatal Zika virus infection causes persistent abnormalities in brain structure, function, and behavior in infant macaques: one year follow-up study
  Volume: 48 Page(s): 277 - 277
  10/01/2019 Authors: Mavigner M; Raper J; Kovacs-Balint Z; Gumber S; Sanchez M; Alvarado M; Chahroudi A
• Similar frequency of infection of naive and memory CD4(+) T-cells in ART-suppressed SIV/SHIV-infected infant rhesus macaques
  Volume: 48 Page(s): 292 - 293
  10/01/2019 Authors: Mattingly C; Goswami R; Nelson A; Schoof N; Shaw G; Bar K; Mavigner M; Van Rompay K; Permar S; Chahroudi A
• Analytical Treatment Interruption after Short-Term Antiretroviral Therapy in a Postnatally Simian-Human Immunodeficiency Virus-Infected Infant Rhesus Macaque Model.
  mBio Volume: 10
  09/05/2019 Authors: Goswami R; Nelson AN; Tu JJ; Dennis M; Feng L; Kumar A; Mangold J; Mangan RJ; Mattingly C; Curtis AD
• Increased CXCR3+ T Cells Impairs Recruitment of T-Helper Type 17 Cells via Interferon and Interleukin 18 in the Small Intestine Mucosa During Treated HIV-1 Infection.
  J Infect Dis Volume: 220 Page(s): 830 - 840
  07/31/2019 Authors: Loiseau C; Requena M; Nayrac M; Mavigner M; Cazabat M; Iscache AL; Carrere N; Suc B; Alric L; Izopet J
• Sting agonist as a kick and kill agent to target the HIV reservoir
  Volume: 22 Page(s): 42 - 42
  07/01/2019 Authors: Mavigner M; Brooks AD; Koblansky A; Galardi C; Madsen H; Margolis DM; Silvestri G; Chahroudi A
• Correction for Mavigner et al., "Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques".
  J Virol Volume: 93
  02/01/2019 Authors: Mavigner M; Habib J; Deleage C; Rosen E; Mattingly C; Bricker K; Kashuba A; Amblard F; Schinazi RF; Lawson B
• Antibody-Mediated CD4 Depletion Induces Homeostatic CD4+ T Cell Proliferation without Detectable Virus Reactivation in Antiretroviral Therapy-Treated Simian Immunodeficiency Virus-Infected Macaques.
  J Virol Volume: 92
  11/15/2018 Authors: Kumar NA; McBrien JB; Carnathan DG; Mavigner M; Mattingly C; White ER; Viviano F; Bosinger SE; Chahroudi A; Silvestri G
• Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques.
  J Virol Volume: 92
  09/15/2018 Authors: Mavigner M; Habib J; Deleage C; Rosen E; Mattingly C; Bricker K; Kashuba A; Amblard F; Schinazi RF; Lawson B
• Short-Term Pegylated Interferon 2a Treatment Does Not Significantly Reduce the Viral Reservoir of Simian Immunodeficiency Virus-Infected, Antiretroviral Therapy-Treated Rhesus Macaques.
  J Virol Volume: 92
  07/15/2018 Authors: Palesch D; Bosinger SE; Mavigner M; Billingsley JM; Mattingly C; Carnathan DG; Paiardini M; Chahroudi A; Vanderford TH; Silvestri G
• Postnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques.
  Sci Transl Med Volume: 10
  04/04/2018 Authors: Mavigner M; Raper J; Kovacs-Balint Z; Gumber S; O'Neal JT; Bhaumik SK; Zhang X; Habib J; Mattingly C; McDonald CE
• Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.
  PLoS Pathog Volume: 14 Page(s): e1006871
  02/01/2018 Authors: Fisher BS; Green RR; Brown RR; Wood MP; Hensley-McBain T; Fisher C; Chang J; Miller AD; Bosche WJ; Lifson JD
• Inhibiting memory CD4+T cell self-renewal to reduce HIV persistence
  Volume: 20 Page(s): 51 - 51
  07/01/2017 Authors: Mavigner M; Zanoni M; Habib J; Mattingly C; Demarest J; Kouji H; Lawson B; Vanderford T; Tharp G; Bosinger S
• Correction for Mylvaganam et al., Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection.
  Proc Natl Acad Sci U S A Volume: 114 Page(s): E3366
  04/18/2017
• In Vivo Models of Human Immunodeficiency Virus Persistence and Cure Strategies.
  J Infect Dis Volume: 215 Page(s): S142 - S151
  03/15/2017 Authors: Nixon CC; Mavigner M; Silvestri G; Garcia JV
• Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection.
  Proc Natl Acad Sci U S A Volume: 114 Page(s): 1976 - 1981
  02/21/2017 Authors: Mylvaganam GH; Rios D; Abdelaal HM; Iyer S; Tharp G; Mavigner M; Hicks S; Chahroudi A; Ahmed R; Bosinger SE
• Quantifying integrated SIV-DNA by repetitive-sampling Alu-gag PCR.
  J Virus Erad Volume: 2 Page(s): 219 - 226
  10/05/2016 Authors: Mavigner M; Lee ST; Habib J; Robinson C; Silvestri G; O'Doherty U; Chahroudi A
• Induction of Unique Subset of Follicular Homing SIV-specific CD8 T Cells by Vaccination Is Associated with Enhanced Control of Pathogenic SIV
  Volume: 32 Page(s): 85 - 85
  10/01/2016 Authors: Mylvaganam G; Reddy P; Rios D; Mohammad H; Gangadhara S; Turner-Styles T; Iyer S; Hicks S; Tharp G; Mavigner M
• CCR6(-) regulatory T cells blunt the restoration of gut Th17 cells along the CCR6-CCL20 axis in treated HIV-1-infected individuals.
  Mucosal Immunol Volume: 9 Page(s): 1137 - 1150
  09/01/2016 Authors: Loiseau C; Requena M; Mavigner M; Cazabat M; Carrere N; Suc B; Barange K; Alric L; Marchou B; Massip P
• Initiation of Antiretroviral Therapy Restores CD4+ T Memory Stem Cell Homeostasis in Simian Immunodeficiency Virus-Infected Macaques.
  J Virol Volume: 90 Page(s): 6699 - 6708
  08/01/2016 Authors: Cartwright EK; Palesch D; Mavigner M; Paiardini M; Chahroudi A; Silvestri G
• Reduced Simian Immunodeficiency Virus Replication in Macrophages of Sooty Mangabeys Is Associated with Increased Expression of Host Restriction Factors.
  J Virol Volume: 89 Page(s): 10136 - 10144
  10/01/2015 Authors: Mir KD; Mavigner M; Wang C; Paiardini M; Sodora DL; Chahroudi AM; Bosinger SE; Silvestri G
• TARGETING SIV RESERVOIRS THROUGH AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANT IN RHESUS MACAQUES
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 380 - 380
  10/01/2014 Authors: Mavigner M; Watkins B; Lawson B; Chahroudi A; Kean L; Silvestri G
• Persistence of virus reservoirs in ART-treated SHIV-infected rhesus macaques after autologous hematopoietic stem cell transplant.
  PLoS Pathog Volume: 10 Page(s): e1004406
  09/01/2014 Authors: Mavigner M; Watkins B; Lawson B; Lee ST; Chahroudi A; Kean L; Silvestri G
• Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques.
  PLoS Pathog Volume: 10 Page(s): e1003958
  03/01/2014 Authors: Chahroudi A; Cartwright E; Lee ST; Mavigner M; Carnathan DG; Lawson B; Carnathan PM; Hashempoor T; Murphy MK; Meeker T
• Altered CD4+ T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals.
  J Clin Invest Volume: 122 Page(s): 62 - 69
  01/01/2012 Authors: Mavigner M; Cazabat M; Dubois M; L'Faqihi F-E; Requena M; Pasquier C; Klopp P; Amar J; Alric L; Barange K
• The myeloid cytokine network in AIDS pathogenesis.
  Cytokine Growth Factor Rev Volume: 23 Page(s): 223 - 231
  01/01/2012 Authors: Mir KD; Mavigner M; Silvestri G
• CXCR4-using viruses in plasma and peripheral blood mononuclear cells during primary HIV-1 infection and impact on disease progression.
  AIDS Volume: 24 Page(s): 2305 - 2312
  09/24/2010 Authors: Raymond S; Delobel P; Mavigner M; Cazabat M; Encinas S; Souyris C; Bruel P; Sandres-Saun K; Marchou B; Massip P
• Shift in phenotypic susceptibility suggests a competition mechanism in a case of acquired resistance to maraviroc.
  AIDS Volume: 24 Page(s): 1382 - 1384
  06/01/2010 Authors: Delobel P; Raymond S; Mavigner M; Cazabat M; Alvarez M; Marchou B; Massip P; Izopet J
• Development and performance of a new recombinant virus phenotypic entry assay to determine HIV-1 coreceptor usage.
  J Clin Virol Volume: 47 Page(s): 126 - 130
  02/01/2010 Authors: Raymond S; Delobel P; Mavigner M; Cazabat M; Souyris C; Encinas S; Bruel P; Sandres-Saun K; Marchou B; Massip P
• Prediction of HIV type 1 subtype C tropism by genotypic algorithms built from subtype B viruses.
  J Acquir Immune Defic Syndr Volume: 53 Page(s): 167 - 175
  02/01/2010 Authors: Raymond S; Delobel P; Mavigner M; Ferradini L; Cazabat M; Souyris C; Sandres-Saun K; Pasquier C; Marchou B; Massip P
• HIV-1 residual viremia correlates with persistent T-cell activation in poor immunological responders to combination antiretroviral therapy.
  PLoS One Volume: 4 Page(s): e7658
  10/30/2009 Authors: Mavigner M; Delobel P; Cazabat M; Dubois M; L'faqihi-Olive F-E; Raymond S; Pasquier C; Marchou B; Massip P; Izopet J
• Genotypic prediction of human immunodeficiency virus type 1 CRF02-AG tropism.
  J Clin Microbiol Volume: 47 Page(s): 2292 - 2294
  07/01/2009 Authors: Raymond S; Delobel P; Mavigner M; Cazabat M; Souyris C; Encinas S; Sandres-Saun K; Pasquier C; Marchou B; Massip P
• Correlation between genotypic predictions based on V3 sequences and phenotypic determination of HIV-1 tropism.
  AIDS Volume: 22 Page(s): F11 - F16
  09/12/2008 Authors: Raymond S; Delobel P; Mavigner M; Cazabat M; Souyris C; Sandres-Saun K; Cuzin L; Marchou B; Massip P; Izopet J
• Direct sequencing of V3 could be a valuable alternative to phenotypic assays for the routine assessment of HIV-1 tropism
  Volume: 13 Page(s): A114 - A114
  01/01/2008 Authors: Raymond S; Delobel P; Mavigner M; Cazabat M; Souyris C; Sandres-Saune K; Cuzin L; Marchou B; Massip P; Izopet J