Publications

• Rolosense: Mechanical Detection of SARS-CoV-2 Using a DNA-Based Motor.
  ACS Cent Sci Volume: 10 Page(s): 1332 - 1347
  07/24/2024 Authors: Piranej S; Zhang L; Bazrafshan A; Marin M; Melikian GB; Salaita K
• Disruption of Transmembrane Phosphatidylserine Asymmetry by HIV-1 Incorporated SERINC5 Is Not Responsible for Virus Restriction.
  Biomolecules Volume: 14
  05/10/2024 Authors: Raghunath G; Abbott EH; Marin M; Wu H; Reyes Ballista JM; Brindley MA; Melikyan GB
• IFITM1 and IFITM3 Proteins Inhibit the Infectivity of Progeny HIV-1 without Disrupting Envelope Glycoprotein Clusters.
  Viruses Volume: 15
  12/07/2023 Authors: Verma S; Chen Y-C; Marin M; Gillespie SE; Melikyan GB
• Human Immunodeficiency Virus 1 Preferentially Fuses with pH-Neutral Endocytic Vesicles in Cell Lines and Human Primary CD4+ T-Cells.
  ACS Nano Volume: 17 Page(s): 17436 - 17450
  09/12/2023 Authors: Sharma M; Marin M; Wu H; Prikryl D; Melikyan GB
• Cyclosporines Antagonize the Antiviral Activity of IFITMProteins by Redistributing Them toward the Golgi Apparatus.
  Biomolecules Volume: 13
  06/03/2023 Authors: Prikryl D; Marin M; Desai TM; Du Y; Fu H; Melikyan GB
• Rolosense: Mechanical detection of SARS-CoV-2 using a DNA-based motor.
  bioRxiv
  02/28/2023 Authors: Piranej S; Zhang L; Bazrafshan A; Marin M; Melikyan GB; Salaita K
• SERINC5-Mediated Restriction of HIV-1 Infectivity Correlates with Resistance to Cholesterol Extraction but Not with Lipid Order of Viral Membrane.
  Viruses Volume: 14
  07/27/2022 Authors: Raghunath G; Chen Y-C; Marin M; Wu H; Melikyan GB
• SERINC5 Restricts HIV-1 Infectivity by Promoting Conformational Changes and Accelerating Functional Inactivation of Env.
  Viruses Volume: 14
  06/25/2022 Authors: Kirschman J; Marin M; Chen Y-C; Chen J; Herschhorn A; Smith AB; Melikyan GB
• The late endosome-resident lipid bis(monoacylglycero)phosphate is a cofactor for Lassa virus fusion.
  PLoS Pathog Volume: 17 Page(s): e1009488
  09/01/2021 Authors: Markosyan RM; Marin M; Zhang Y; Cohen FS; Melikyan GB
• Human Defensins Inhibit SARS-CoV-2 Infection by Blocking Viral Entry.
  Viruses Volume: 13
  06/26/2021 Authors: Xu C; Wang A; Marin M; Honnen W; Ramasamy S; Porter E; Subbian S; Pinter A; Melikyan GB; Lu W
• Interferon-Induced Transmembrane Protein 3 Blocks Fusion of Diverse Enveloped Viruses by Altering Mechanical Properties of Cell Membranes.
  ACS Nano Volume: 15 Page(s): 8155 - 8170
  05/25/2021 Authors: Guo X; Steinkhler J; Marin M; Li X; Lu W; Dimova R; Melikyan GB
• Publisher Correction: HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains.
  Nat Commun Volume: 11 Page(s): 6165
  11/26/2020 Authors: Francis AC; Marin M; Singh PK; Achuthan V; Prellberg MJ; Palermino-Rowland K; Lan S; Tedbury PR; Sarafianos SG; Engelman AN
• HIV-1 Uncoating and Nuclear Import Precede the Completion of Reverse Transcription in Cell Lines and in Primary Macrophages.
  Viruses Volume: 12
  10/30/2020 Authors: Francis AC; Marin M; Prellberg MJ; Palermino-Rowland K; Melikyan GB
• Super-Resolution Fluorescence Imaging Reveals That Serine Incorporator Protein 5 Inhibits Human Immunodeficiency Virus Fusion by Disrupting Envelope Glycoprotein Clusters.
  ACS Nano Volume: 14 Page(s): 10929 - 10943
  09/22/2020 Authors: Chen Y-C; Sood C; Marin M; Aaron J; Gratton E; Salaita K; Melikyan GB
• HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains.
  Nat Commun Volume: 11 Page(s): 3505
  07/14/2020 Authors: Francis AC; Marin M; Singh PK; Achuthan V; Prellberg MJ; Palermino-Rowland K; Lan S; Tedbury PR; Sarafianos SG; Engelman AN
• HIV-1 Fusion with CD4+ T cells Is Promoted by Proteins Involved in Endocytosis and Intracellular Membrane Trafficking.
  Viruses Volume: 11
  01/25/2019 Authors: Marin M; Kushnareva Y; Mason CS; Chanda SK; Melikyan GB
• Interferon-induced transmembrane protein 3 blocks fusion of sensitive but not resistant viruses by partitioning into virus-carrying endosomes.
  PLoS Pathog Volume: 15 Page(s): e1007532
  01/01/2019 Authors: Suddala KC; Lee CC; Meraner P; Marin M; Markosyan RM; Desai TM; Cohen FS; Brass AL; Melikyan GB
• Lassa Fever Virus Glycoprotein Mediates LAMP1-and Low pH-Dependent Cell-Cell Fusion through a Stalk-Pore Mechanism
  Volume: 114 Page(s): 605A - 605A
  02/02/2018 Authors: Markosyan RM; Marin M; Cohen FS; Melikyan GB
• Fusion Stage of HIV-1 Entry Depends on Virus-Induced Cell Surface Exposure of Phosphatidylserine.
  Cell Host Microbe Volume: 22 Page(s): 99 - 110.e7
  07/12/2017 Authors: Zaitseva E; Zaitsev E; Melikov K; Arakelyan A; Marin M; Villasmil R; Margolis LB; Melikyan GB; Chernomordik LV
• pH regulation in early endosomes and interferon-inducible transmembrane proteins control avian retrovirus fusion.
  J Biol Chem Volume: 292 Page(s): 7817 - 7827
  05/12/2017 Authors: Desai TM; Marin M; Mason C; Melikyan GB
• SERINC5 protein inhibits HIV-1 fusion pore formation by promoting functional inactivation of envelope glycoproteins.
  J Biol Chem Volume: 292 Page(s): 6014 - 6026
  04/07/2017 Authors: Sood C; Marin M; Chande A; Pizzato M; Melikyan GB
• SERINC5 Inhibits HIV Fusion through Inactivation of Env Glycoproteins and Interference with Productive Refolding of Env
  Volume: 112 Page(s): 79A - 79A
  02/03/2017 Authors: Sood C; Marin M; Chande A; Mattheyses AL; Salaita K; Pizzato M; Melikian G
• Computational analyses of the ExoS protein, a component of Sinorhizobium meliloti ExoR-ExoS/ChvI pathway.
  Volume: 28
  01/01/2017 Authors: Marin M; Sood C; Chande A; Pizzato M; Melikian GB
• Screening and Functional Profiling of Small-Molecule HIV-1 Entry and Fusion Inhibitors.
  Assay Drug Dev Technol Volume: 15 Page(s): 53 - 63
  01/01/2017 Authors: Giroud C; Du Y; Marin M; Min Q; Jui NT; Fu H; Melikyan GB
• Correlated fluorescence microscopy and cryo-electron tomography of virus-infected or transfected mammalian cells.
  Nat Protoc Volume: 12 Page(s): 150 - 167
  01/01/2017 Authors: Hampton CM; Strauss JD; Ke Z; Dillard RS; Hammonds JE; Alonas E; Desai TM; Marin M; Storms RE; Leon F
• Click labeling of unnatural sugars metabolically incorporated into viral envelope glycoproteins enables visualization of single particle fusion.
  J Virol Methods Volume: 233 Page(s): 62 - 71
  07/01/2016 Authors: Oum YH; Desai TM; Marin M; Melikyan GB
• Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells.
  PLoS Pathog Volume: 12 Page(s): e1005709
  06/01/2016 Authors: Francis AC; Marin M; Shi J; Aiken C; Melikyan GB
• Single-Particle Tracking of HIV-1 Virions Bearing an Extra-Viral Fluorescent pH Sensor Reveals Viral Entry occurs after Trafficking to an Acidic Cellular Compartment
  Volume: 110 Page(s): 249A - 249A
  02/16/2016 Authors: Sood C; Marin M; Mason CS; Melikyan GB
• Movements of HIV-1 genomic RNA-APOBEC3F complexes and PKR reveal cytoplasmic and nuclear PKR defenses and HIV-1 evasion strategies.
  Virus Res Volume: 213 Page(s): 124 - 139
  02/02/2016 Authors: Marin M; Golem S; Kozak SL; Kabat D
• Visualization of Content Release from Cell Surface-Attached Single HIV-1 Particles Carrying an Extra-Viral Fluorescent pH-Sensor.
  PLoS One Volume: 11 Page(s): e0148944
  01/01/2016 Authors: Sood C; Marin M; Mason CS; Melikyan GB
• Fluorescent protein-tagged Vpr dissociates from HIV-1 core after viral fusion and rapidly enters the cell nucleus.
  Retrovirology Volume: 12 Page(s): 88
  10/29/2015 Authors: Desai TM; Marin M; Sood C; Shi J; Nawaz F; Aiken C; Melikyan GB
• P2X1 Receptor Antagonists Inhibit HIV-1 Fusion by Blocking Virus-Coreceptor Interactions.
  J Virol Volume: 89 Page(s): 9368 - 9382
  09/01/2015 Authors: Giroud C; Marin M; Hammonds J; Spearman P; Melikyan GB
• High-Throughput HIV-Cell Fusion Assay for Discovery of Virus Entry Inhibitors.
  Assay Drug Dev Technol Volume: 13 Page(s): 155 - 166
  04/01/2015 Authors: Marin M; Du Y; Giroud C; Kim JH; Qui M; Fu H; Melikyan GB
• Distinct requirements for HIV-cell fusion and HIV-mediated cell-cell fusion.
  J Biol Chem Volume: 290 Page(s): 6558 - 6573
  03/06/2015 Authors: Kondo N; Marin M; Kim JH; Desai TM; Melikyan GB
• Can HIV-1 entry sites be deduced by comparing bulk endocytosis to functional readouts for viral fusion?
  J Virol Volume: 89 Page(s): 2985
  03/01/2015 Authors: Marin M; Melikyan GB
• Defining a Retrovirus Entry Site by Single Particle Tracking
  Volume: 108 Page(s): 354A - 354A
  01/27/2015 Authors: Melikian G; Padilla-Parra S; Kondo N; Marin M
• Real-Time Imaging Reveals that HIV-1 Vpr Dissociates from the Core and Accumulates in the Nucleus after Viral Fusion
  Volume: 108 Page(s): 408A - 408A
  01/27/2015 Authors: Desai TM; Marin M; Melikyan GB
• Pinpointing retrovirus entry sites in cells expressing alternatively spliced receptor isoforms by single virus imaging.
  Retrovirology Volume: 11 Page(s): 47
  06/16/2014 Authors: Padilla-Parra S; Marin M; Kondo N; Melikyan GB
• IFITM3 restricts influenza A virus entry by blocking the formation of fusion pores following virus-endosome hemifusion.
  PLoS Pathog Volume: 10 Page(s): e1004048
  04/01/2014 Authors: Desai TM; Marin M; Chin CR; Savidis G; Brass AL; Melikyan GB
• Imaging fusion of single vesicular stomatitis virus with supported lipid bilayers
  Volume: 42 Page(s): S102 - S102
  07/01/2013 Authors: Matos PM; Marin M; Ahn B; Lam W; Santos NC; Melikyan GB
• Anionic lipids are required for vesicular stomatitis virus G protein-mediated single particle fusion with supported lipid bilayers.
  J Biol Chem Volume: 288 Page(s): 12416 - 12425
  05/03/2013 Authors: Matos PM; Marin M; Ahn B; Lam W; Santos NC; Melikyan GB
• Sub-inhibitory concentrations of human -defensin potentiate neutralizing antibodies against HIV-1 gp41 pre-hairpin intermediates in the presence of serum.
  PLoS Pathog Volume: 9 Page(s): e1003431
  01/01/2013 Authors: Demirkhanyan L; Marin M; Lu W; Melikyan GB
• Fusion of mature HIV-1 particles leads to complete release of a gag-GFP-based content marker and raises the intraviral pH.
  PLoS One Volume: 8 Page(s): e71002
  01/01/2013 Authors: Padilla-Parra S; Marin M; Gahlaut N; Suter R; Kondo N; Melikyan GB
• Quantitative imaging of endosome acidification and single retrovirus fusion with distinct pools of early endosomes.
  Proc Natl Acad Sci U S A Volume: 109 Page(s): 17627 - 17632
  10/23/2012 Authors: Padilla-Parra S; Matos PM; Kondo N; Marin M; Santos NC; Melikyan GB
• Multifaceted mechanisms of HIV-1 entry inhibition by human -defensin.
  J Biol Chem Volume: 287 Page(s): 28821 - 28838
  08/17/2012 Authors: Demirkhanyan LH; Marin M; Padilla-Parra S; Zhan C; Miyauchi K; Jean-Baptiste M; Novitskiy G; Lu W; Melikyan GB
• Synchronized retrovirus fusion in cells expressing alternative receptor isoforms releases the viral core into distinct sub-cellular compartments.
  PLoS Pathog Volume: 8 Page(s): e1002694
  01/01/2012 Authors: Padilla-Parra S; Marin M; Kondo N; Melikyan GB
• Inhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusion.
  Retrovirology Volume: 8 Page(s): 99
  12/06/2011 Authors: de la Vega M; Marin M; Kondo N; Miyauchi K; Kim Y; Epand RF; Epand RM; Melikyan GB
• Visualization of retrovirus uptake and delivery into acidic endosomes.
  Biochem J Volume: 434 Page(s): 559 - 569
  03/15/2011 Authors: Miyauchi K; Marin M; Melikyan GB
• Entry Pathways of an Avian Virus into Cells Expressing Transmembrane and GPI-Anchored Receptor Isoforms
  Volume: 100 Page(s): 634 - 634
  02/02/2011 Authors: Jha N; Martin E; Latinovic O; Marin M; Novitskiy G; Miyauchi K; Melikian G
• Imaging single retrovirus entry through alternative receptor isoforms and intermediates of virus-endosome fusion.
  PLoS Pathog Volume: 7 Page(s): e1001260
  01/20/2011 Authors: Jha NK; Latinovic O; Martin E; Novitskiy G; Marin M; Miyauchi K; Naughton J; Young JAT; Melikyan GB
• Human immunodeficiency virus type 1 Vif functionally interacts with diverse APOBEC3 cytidine deaminases and moves with them between cytoplasmic sites of mRNA metabolism.
  J Virol Volume: 82 Page(s): 987 - 998
  01/01/2008 Authors: Marin M; Golem S; Rose KM; Kozak SL; Kabat D
• Vaccine effectiveness against medically attended, laboratory-confirmed influenza among children aged 6 to 59 months, 2003-2004.
  Pediatrics Volume: 119 Page(s): e587 - e595
  03/01/2007 Authors: Shuler CM; Iwamoto M; Bridges CB; Marin M; Neeman R; Gargiullo P; Yoder TA; Keyserling HL; Terebuh PD
• The anti-HIV-1 editing enzyme APOBEC3G binds HIV-1 RNA and messenger RNAs that shuttle between polysomes and stress granules.
  J Biol Chem Volume: 281 Page(s): 29105 - 29119
  09/29/2006 Authors: Kozak SL; Marin M; Rose KM; Bystrom C; Kabat D
• AIDS-related discrimination in Asia.
  AIDS Care Volume: 17 Page(s): 413 - 424
  05/01/2005 Authors: Paxton S; Gonzales G; Uppakaew K; Abraham KK; Okta S; Green C; Nair KS; Merati TP; Thephthien B; Marin M
• Immunotherapy of a viral disease by in vivo production of therapeutic monoclonal antibodies.
  Hum Gene Ther Volume: 11 Page(s): 1407 - 1415
  07/01/2000 Authors: Pelegrin M; Marin M; Oates A; Nol D; Saller R; Salmons B; Piechaczyk M
• Antiviral activity of an intracellularly expressed single-chain antibody fragment directed against the murine leukemia virus capsid protein.
  Hum Gene Ther Volume: 11 Page(s): 389 - 401
  02/10/2000 Authors: Marin M; Pelegrin-Zurilla M; Bachrach E; Nol D; Brockly F; Piechaczyk M
• Cell targeting by murine retroviral vectors.
  Crit Rev Oncol Hematol Volume: 28 Page(s): 7 - 30
  06/01/1998 Authors: Karavanas G; Marin M; Salmons B; Gnzburg WH; Piechaczyk M
• Systemic long-term delivery of antibodies in immunocompetent animals using cellulose sulphate capsules containing antibody-producing cells.
  Gene Ther Volume: 5 Page(s): 828 - 834
  06/01/1998 Authors: Pelegrin M; Marin M; Nol D; Del Rio M; Saller R; Stange J; Mitzner S; Gnzburg WH; Piechaczyk M
• Affinity of recombinant antibody and antibody fragment binding to human thyroglobulin: potential applications in gene therapy.
  J Mol Recognit Volume: 11 Page(s): 117 - 118
  01/01/1998 Authors: Mani JC; Noel D; Marin M; Navarro-Teulon I; Biard-Piechaczyk M; Pau B; Piechaczyk M
• Towards efficient cell targeting by recombinant retroviruses.
  Mol Med Today Volume: 3 Page(s): 396 - 403
  09/01/1997 Authors: Marin M; Nol D; Piechaczyk M
• In vitro and in vivo secretion of cloned antibodies by genetically modified myogenic cells.
  Hum Gene Ther Volume: 8 Page(s): 1219 - 1229
  07/01/1997 Authors: Nol D; Pelegrin M; Marin M; Biard-Piechaczyk M; Ourlin JC; Mani JC; Piechaczyk M
• Expression in Escherichia coli of soluble and M13 phage-displayed forms of a single-chain antibody fragment specific for digoxin: Assessment in a novel drug immunoassay (vol 1, pg 41, 1995)
  IMMUNOTECHNOLOGY Volume: 1 Page(s): 243 - 244
  12/01/1995 Authors: NavarroTeulon I; PeraldiRoux S; Bernardi T; Marin M; Piechaczyk M; Shire D; Pau B; BiardPiechaczyk M
• Expression in Escherichia coli of soluble and M13 phage-displayed forms of a single-chain antibody fragment specific for digoxin: assessment in a novel drug immunoassay.
  Immunotechnology Volume: 1 Page(s): 41 - 52
  05/01/1995 Authors: Navarro-Teulon I; Peraldi-Roux S; Bernardi T; Marin M; Piechaczyk M; Shire D; Pau B; Biard-Piechaczyk M
• A new class of potential carcinogenesis inhibitors: hindered p-benzoquinones.
  Neoplasma Volume: 38 Page(s): 545 - 557
  01/01/1991 Authors: Niculescu-Duvz I; Herdan J; Stoica G; Lupu F; Arnutu M; Cinc S; Eliescu R; Voiculetz N
• Mechanisms of cancerogenesis inhibition. II. The aminophenols and their oxidation products.
  Neoplasma Volume: 35 Page(s): 539 - 548
  01/01/1988 Authors: Niculescu-Duvaz I; Stoica G; Lupu F; Arnautu M; Voiculetz N