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Profile

Michael Kuhar PhD

  • Department of Pharmacology & Chemical Biology
    Professor Emeritus
  • (404) 727-3274
  • mkuhar@emory.edu
  • Dr. Kuhar's Website
Head shot of Michael Kuhar

Overview

Michael Kuhar, PhD, is a Researcher at Emory National Primate Research Center, Candler Professor of Neuropharmacology at Emory University School of Medicine and Senior Fellow in the Center for Ethics at Emory.

Dr. Kuhar has spent more than four decades as a neuroscience and neuropharmacology researcher. His studies have focused on the cellular and anatomical bases of addiction in order to pave the way for a new class of drugs to target addiction and obesity through a better understanding of CART peptides. These specific peptides are neurotransmitters that have been implicated in the regulation of feeding, body weight, drug reward and stress.

With his more than 900 scientific publications, Dr. Kuhar is the most cited researcher at Emory. He has trained more than 60 students, research fellows and visitors, and he is the author of The Addicted Brain, Why we abuse drugs, alcohol, and nicotine (2012 Pearson Education/FT Press) and The Art and Ethics of Being a Good Colleague (2013 CreateSpace Independent Publishing Platform). His latest book is the basis for the "Michael Kuhar on Getting Collegial" article in the Spring 2014 issue of Emory Magazine.

In 2011, Dr. Kuhar received the Nathan B. Eddy Memorial Award from the College on Problems of Drug Dependence to honor his lifetime achievements in research that have advanced the understanding of drug dependence.

A recent interest of Dr. Kuhar's is working with Tibetan monks who are part of the community of the Dalai Lama in Exile. Dr. Kuhar is a member of the Emory-Tibet Science Initiative (ETSI) and taught information about neurotransmission and drug addiction as part of a Neuroscience course for Tibetan Buddhist monks and nuns. Dr. Kuhar has traveled to India twice as part of the ETSI.

This summer, Dr. Kuhar is offering an expert glimpse into addiction research through Coursera, an Emory partner for MOOCs (massive open online courses). The course, "The Addicted Brain," examines addiction to drugs and other behaviors. In the course, Dr. Kuhar describes what happens in the brain and how this information helps us deal with and overcome addiction.

Academic Appointment

  • Research Professor, Emory National Primate Research Center
  • Candler Professor of Neuropharmacology, Pharmacology, Emory University School of Medicine

Education

Degrees

  • PhD from Johns Hopkins University

Research

Publications

  • Commentary: GPR160 De-Orphanization Reveals Critical Roles in Neuropathic Pain in Rodents (Finally, a Receptor for CART Peptide).
    Adv Drug Alcohol Res Volume: 1 Page(s): 10012
    01/01/2021 Authors: Job MO; Kuhar MJ
  • CART peptide in the nucleus accumbens regulates psychostimulants: Correlations between psychostimulant and CART peptide effects.
    Neuroscience Volume: 348 Page(s): 135 - 142
    04/21/2017 Authors: Job MO; Kuhar MJ
  • CART Peptide Regulates Psychostimulant-Induced Activity and Exhibits a Rate Dependency.
    J Drug Alcohol Res Volume: 6
    01/01/2017 Authors: Kuhar MJ; Job MO
  • CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.
    Diabetologia Volume: 59 Page(s): 1928 - 1937
    09/01/2016 Authors: Abels M; Riva M; Bennet H; Ahlqvist E; Dyachok O; Nagaraj V; Shcherbina L; Fred RG; Poon W; Srhede-Winzell M
  • CART Peptides and Drugs of Abuse: A Review of Recent Progress.
    J Drug Alcohol Res Volume: 5
    01/01/2016 Authors: Kuhar MJ
  • Cocaine-and-Amphetamine Regulated Transcript (CART) peptide attenuates dopamine- and cocaine-mediated locomotor activity in both male and female rats: lack of sex differences.
    Neuropeptides Volume: 48 Page(s): 75 - 81
    04/01/2014 Authors: Job MO; Perry J; Shen LL; Kuhar MJ
  • A novel validated and sensitive LC-MS/MS method in monkey plasma for simultaneous determination of methamphetamine and its metabolites in methamphetamine-treated monkey plasma
    Volume: 9 Page(s): 14 - 15
    03/01/2014 Authors: Earla R; Bosinger S; Shah A; Gangwani MR; Nookala A; Liu X; Cao L; Kuhar MJ; Kumar S; Fox HS
  • Letter from the Editor-in-Chief: Irreproducible Results.
    J Drug Alcohol Res Volume: 3
    01/01/2014 Authors: Kuhar MJ
  • Collegial ethics: supporting our colleagues.
    Sci Eng Ethics Volume: 19 Page(s): 677 - 684
    09/01/2013 Authors: Kuhar MJ; Cross D
  • The inhibition of cocaine-induced locomotor activity by CART 55-102 is lost after repeated cocaine administration.
    Neurosci Lett Volume: 550 Page(s): 179 - 183
    08/29/2013 Authors: Job MO; Shen LL; Kuhar MJ
  • Affinity labeling of membrane receptors using tissue-penetrating radiations.
    Biomed Res Int Volume: 2013 Page(s): 503095
    01/01/2013 Authors: Wong FC; Boja J; Ho B; Kuhar MJ; Wong DF
  • Intra-accumbal administration of shRNAs against CART peptides cause increases in body weight and cocaine-induced locomotor activity in rats.
    Brain Res Volume: 1482 Page(s): 47 - 54
    10/30/2012 Authors: Job MO; Licata J; Hubert GW; Kuhar MJ
  • Region- and sex-specific changes in CART mRNA in rat hypothalamic nuclei induced by forced swim stress.
    Brain Res Volume: 1479 Page(s): 62 - 71
    10/15/2012 Authors: Balkan B; Gozen O; Koylu EO; Keser A; Kuhar MJ; Pogun S
  • The cocaine- and amphetamine-regulated transcript mediates ligand-independent activation of ER, and is an independent prognostic factor in node-negative breast cancer.
    Oncogene Volume: 31 Page(s): 3483 - 3494
    07/26/2012 Authors: Brennan DJ; O'Connor DP; Laursen H; McGee SF; McCarthy S; Zagozdzon R; Rexhepaj E; Culhane AC; Martin FM; Duffy MJ
  • Forced swim stress elicits region-specific changes in CART expression in the stress axis and stress regulatory brain areas.
    Brain Res Volume: 1432 Page(s): 56 - 65
    01/13/2012 Authors: Balkan B; Keser A; Gozen O; Koylu EO; Dagci T; Kuhar MJ; Pogun S
  • Intraperitoneal Administration of CART 55-102 Inhibits Psychostimulant-Induced Locomotion.
    J Drug Alcohol Res Volume: 1
    01/01/2012 Authors: Job MO; Kuhar MJ
  • Collegial ethics: what, why and how.
    Drug Alcohol Depend Volume: 119 Page(s): 235 - 238
    12/15/2011 Authors: Kuhar MJ
  • CART peptide stimulation of G protein-mediated signaling in differentiated PC12 cells: identification of PACAP 6-38 as a CART receptor antagonist.
    Neuropeptides Volume: 45 Page(s): 351 - 358
    10/01/2011 Authors: Lin Y; Hall RA; Kuhar MJ
  • CART Peptides Regulate Psychostimulants and May be Endogenous Antidepressants.
    Curr Neuropharmacol Volume: 9 Page(s): 12 - 16
    03/01/2011 Authors: Job MO; McNamara IM; Kuhar MJ
  • Understanding the Global Problem of Drug Addiction is a Challenge for IDARS Scientists.
    Curr Neuropharmacol Volume: 9 Page(s): 2 - 7
    03/01/2011 Authors: Ali SF; Onaivi ES; Dodd PR; Cadet JL; Schenk S; Kuhar MJ; Koob GF
  • New Research Frontiers and Advances in Drug Addiction PREFACE
    CURRENT NEUROPHARMACOLOGY Volume: 9 Page(s): 1 - 1
    03/01/2011 Authors: Ali SF; Onaivi E; Kim H-C; Kuhar MJ; Koob G
  • CART peptide inhibits locomotor activity induced by simultaneous stimulation of D1 and D2 receptors, but not by stimulation of individual dopamine receptors.
    Synapse Volume: 65 Page(s): 1 - 7
    01/01/2011 Authors: Moffett MC; Song J; Kuhar MJ
  • Developing and communicating responsible data management policies to trainees and colleagues.
    Sci Eng Ethics Volume: 16 Page(s): 753 - 762
    12/01/2010 Authors: Frugoli J; Etgen AM; Kuhar M
  • Chromatin immunoprecipitation assays revealed CREB and serine 133 phospho-CREB binding to the CART gene proximal promoter.
    Brain Res Volume: 1344 Page(s): 1 - 12
    07/16/2010 Authors: Rogge GA; Shen L-L; Kuhar MJ
  • Wake promoting effects of cocaine and amphetamine-regulated transcript (CART).
    Neuropeptides Volume: 44 Page(s): 241 - 246
    06/01/2010 Authors: Keating GL; Kuhar MJ; Bliwise DL; Rye DB
  • Developing and Communicating Responsible Data Management Policies to Trainees and Colleagues.
    Sci Eng Ethics
    04/27/2010 Authors: Frigoli J; Etgen AM; Kuhar M
  • Conversation with Michael Kuhar.
    Addiction Volume: 105 Page(s): 593 - 600
    04/01/2010 Authors: Kuhar M
  • CREB regulation of the CART gene in the rat nucleus accumbens and GH3 cultured cells
    Volume: 24
    04/01/2010 Authors: Rogge GA; Jones DC; Nestler E; Kuhar MJ
  • CART peptide may be an endogenous antidepressant
    Volume: 24
    04/01/2010 Authors: Job M; McNamera I; Kuhar M
  • Measuring levels of proteins by various technologies: can we learn more by measuring turnover?
    Biochem Pharmacol Volume: 79 Page(s): 665 - 668
    03/01/2010 Authors: Kuhar MJ
  • CART peptides: regulators of body weight, reward and other functions (vol 9, pg 747, 2008)
    NATURE REVIEWS NEUROSCIENCE Volume: 11
    03/01/2010 Authors: Rogge G; Jones D; Hubert GW; Lin Y; Kuhar MJ
  • Cocaine and amphetamine-regulated transcript-containing neurons in the nucleus accumbens project to the ventral pallidum in the rat and may inhibit cocaine-induced locomotion.
    Neuroscience Volume: 165 Page(s): 179 - 187
    01/13/2010 Authors: Hubert GW; Manvich DF; Kuhar MJ
  • Blacklisting among scientists.
    Synapse Volume: 63 Page(s): 539 - 540
    07/01/2009 Authors: Kuhar MJ
  • Regulation of cocaine- and amphetamine-regulated transcript mRNA expression by calcium-mediated signaling in GH3 cells.
    Neuroscience Volume: 160 Page(s): 339 - 347
    05/05/2009 Authors: Jones DC; Lakatos A; Rogge GA; Kuhar MJ
  • On the use of protein turnover and half-lives.
    Neuropsychopharmacology Volume: 34 Page(s): 1172 - 1173
    04/01/2009 Authors: Kuhar MJ
  • Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo.
    Brain Res Volume: 1251 Page(s): 42 - 52
    01/28/2009 Authors: Rogge GA; Jones DC; Green T; Nestler E; Kuhar MJ
  • NEONATAL COLD PANNICULITIS INDUCED BY ICE BAG TREATMENT FOR SUPRAVENTRICULAR TACHYCARDIA
    Volume: 36 Page(s): 119 - 119
    01/01/2009 Authors: Kuhar M; Moores W; Hinds B
  • CART peptides: regulators of body weight, reward and other functions.
    Nat Rev Neurosci Volume: 9 Page(s): 747 - 758
    10/01/2008 Authors: Rogge G; Jones D; Hubert GW; Lin Y; Kuhar MJ
  • On blacklisting in science.
    Sci Eng Ethics Volume: 14 Page(s): 301 - 303
    09/01/2008 Authors: Kuhar MJ
  • Frequency of maternal licking and grooming correlates negatively with vulnerability to cocaine and alcohol use in rats.
    Pharmacol Biochem Behav Volume: 90 Page(s): 497 - 500
    09/01/2008 Authors: Francis DD; Kuhar MJ
  • Unique responses of midbrain CART neurons in macaques to ovarian steroids.
    Brain Res Volume: 1227 Page(s): 76 - 88
    08/28/2008 Authors: Lima FB; Henderson JA; Reddy AP; Tokuyama Y; Hubert GW; Kuhar MJ; Bethea CL
  • Injection of CART (cocaine- and amphetamine-regulated transcript) peptide into the nucleus accumbens reduces cocaine self-administration in rats.
    Behav Brain Res Volume: 191 Page(s): 266 - 271
    08/22/2008 Authors: Jaworski JN; Hansen ST; Kuhar MJ; Mark GP
  • Cocaine administration increases the fraction of CART cells in the rat nucleus accumbens that co-immunostain for c-Fos.
    Neuropeptides Volume: 42 Page(s): 339 - 343
    06/01/2008 Authors: Hubert GW; Kuhar MJ
  • High dose CART peptide induces abnormal EEG activity and behavioral seizures.
    Neuropeptides Volume: 42 Page(s): 199 - 204
    04/01/2008 Authors: Keating GL; Kuhar MJ; Rye DB
  • Periodic fever syndrome with aphthous stomatitis, pharyngitis and cervical adenopathy treated with ketotifen - a case report
    Volume: 26 Page(s): 213 - 213
    03/01/2008 Authors: Toplak N; Glavnik V; Kuhar M; Avcin T
  • CART receptor binding in primary cell cultures of the rat nucleus accumbens.
    Synapse Volume: 62 Page(s): 122 - 127
    02/01/2008 Authors: Jones DC; Kuhar MJ
  • CART peptides as modulators of dopamine and psychostimulants and interactions with the mesolimbic dopaminergic system.
    Biochem Pharmacol Volume: 75 Page(s): 57 - 62
    01/01/2008 Authors: Hubert GW; Jones DC; Moffett MC; Rogge G; Kuhar MJ
  • CART deficiency increases body weight but does not alter bone strength.
    J Musculoskelet Neuronal Interact Volume: 8 Page(s): 146 - 153
    01/01/2008 Authors: Bartell SM; Isales CM; Baile CA; Kuhar MJ; Hamrick MW
  • Increased metabolism in the R6/2 mouse model of Huntington's disease.
    Neurobiol Dis Volume: 29 Page(s): 41 - 51
    01/01/2008 Authors: van der Burg JMM; Bacos K; Wood NI; Lindqvist A; Wierup N; Woodman B; Wamsteeker JI; Smith R; Deierborg T; Kuhar MJ
  • Synthesis, monoamine transporter binding, properties, and functional monoamine uptake activity of 3beta-[4-methylphenyl and 4-chlorophenyl]-2 beta-[5-(substituted phenyl)thiazol-2-yl]tropanes.
    J Med Chem Volume: 50 Page(s): 3686 - 3695
    07/26/2007 Authors: Gong PK; Blough BE; Brieaddy LE; Huang X; Kuhar MJ; Navarro HA; Carroll FI
  • Sex differences in the regulation of cocaine and amphetamine-regulated transcript expression in hypothalamic nuclei of rats by forced swim stress.
    Synapse Volume: 61 Page(s): 561 - 568
    07/01/2007 Authors: Gozen O; Balkan B; Yararbas G; Koylu EO; Kuhar MJ; Pogun S
  • CART-peptide immunoreactivity in enteric nerves in patients with Hirschsprung's disease.
    Eur J Pediatr Surg Volume: 17 Page(s): 184 - 189
    06/01/2007 Authors: Gunnarsdttir A; Wierup N; Larsson LT; Kuhar MJ; Ekblad E
  • Intra-VTA CART 55-102 reduces the locomotor effect of systemic cocaine in rats: an isobolographic analysis.
    Neuropeptides Volume: 41 Page(s): 65 - 72
    04/01/2007 Authors: Jaworski JN; Kimmel HL; Mitrano DA; Tallarida RJ; Kuhar MJ
  • Maternal separation alters drug intake patterns in adulthood in rats.
    Biochem Pharmacol Volume: 73 Page(s): 321 - 330
    02/01/2007 Authors: Moffett MC; Vicentic A; Kozel M; Plotsky P; Francis DD; Kuhar MJ
  • Effects of dopamine transporter selective 3-phenyltropane analogs on locomotor activity, drug discrimination, and cocaine self-administration after oral administration.
    Eur J Pharmacol Volume: 553 Page(s): 149 - 156
    12/28/2006 Authors: Carroll FI; Fox BS; Kuhar MJ; Howard JL; Pollard GT; Schenk S
  • Colocalization of CART peptide with prodynorphin and dopamine D1 receptors in the rat nucleus accumbens.
    Neuropeptides Volume: 40 Page(s): 409 - 415
    12/01/2006 Authors: Hubert GW; Kuhar MJ
  • CART, a new player in the regulation of islet hormone secretion
    Volume: 49 Page(s): 313 - 314
    09/01/2006 Authors: Wierup N; Bjorkqvist M; Mulder H; Kuhar MJ; Ahren B; Sundler F
  • Cocaine and amphetamine regulated transcript (CART) and the stress response.
    Peptides Volume: 27 Page(s): 1956 - 1969
    08/01/2006 Authors: Koylu EO; Balkan B; Kuhar MJ; Pogun S
  • Intrathecal CART (55-102) attenuates hyperlagesia and allodynia in a mouse model of neuropathic but not inflammatory pain.
    Peptides Volume: 27 Page(s): 2019 - 2023
    08/01/2006 Authors: Damaj MI; Zheng J; Martin BR; Kuhar MJ
  • Studies of cocaine- and amphetamine-regulated transcript (CART) knockout mice.
    Peptides Volume: 27 Page(s): 2037 - 2045
    08/01/2006 Authors: Moffett M; Stanek L; Harley J; Rogge G; Asnicar M; Hsiung H; Kuhar M
  • Should Codes of Ethics include expectations of others?
    Sci Eng Ethics Volume: 12 Page(s): 413 - 414
    07/01/2006 Authors: Kuhar MJ
  • Modeling the onset of drug dependence: a consideration of the requirement for protein synthesis.
    J Theor Biol Volume: 240 Page(s): 531 - 537
    06/21/2006 Authors: Joyce AR; Easterling K; Holtzman SG; Kuhar MJ
  • Maternal separation alters serotonergic transporter densities and serotonergic 1A receptors in rat brain.
    Neuroscience Volume: 140 Page(s): 355 - 365
    06/19/2006 Authors: Vicentic A; Francis D; Moffett M; Lakatos A; Rogge G; Hubert GW; Harley J; Kuhar MJ
  • CART expression in limbic regions of rat brain following forced swim stress: sex differences.
    Neuropeptides Volume: 40 Page(s): 185 - 193
    06/01/2006 Authors: Balkan B; Gozen O; Yararbas G; Koylu EO; Akinturk S; Kuhar MJ; Pogun S
  • Maternal separation and handling affects cocaine self-administration in both the treated pups as adults and the dams.
    J Pharmacol Exp Ther Volume: 317 Page(s): 1210 - 1218
    06/01/2006 Authors: Moffett MC; Harley J; Francis D; Sanghani SP; Davis WI; Kuhar MJ
  • Regulation of CART mRNA in the rat nucleus accumbens via D3 dopamine receptors.
    Neuropharmacology Volume: 50 Page(s): 858 - 864
    06/01/2006 Authors: Hunter RG; Jones D; Vicentic A; Hue G; Rye D; Kuhar MJ
  • Cocaine-amphetamine-regulated transcript expression in the rat nucleus accumbens is regulated by adenylyl cyclase and the cyclic adenosine 5'-monophosphate/protein kinase a second messenger system.
    J Pharmacol Exp Ther Volume: 317 Page(s): 454 - 461
    04/01/2006 Authors: Jones DC; Kuhar MJ
  • CART peptides as modulators of mesolimbic dopamine and psychostimulants
    Volume: 40 Page(s): 148 - 148
    04/01/2006 Authors: Kuhar MJ
  • Development of the dopamine transporter selective RTI-336 as a pharmacotherapy for cocaine abuse.
    AAPS J Volume: 8 Page(s): E196 - E203
    03/24/2006 Authors: Carroll FI; Howard JL; Howell LL; Fox BS; Kuhar MJ
  • CART peptide receptors: Specific binding in AtT20 cells
    Volume: 20 Page(s): A685 - A685
    03/06/2006 Authors: Vicentic A; Lakatos A; Kuhar M; Ntl Y
  • CART regulates islet hormone secretion and is expressed in the beta-cells of type 2 diabetic rats.
    Diabetes Volume: 55 Page(s): 305 - 311
    02/01/2006 Authors: Wierup N; Bjrkqvist M; Kuhar MJ; Mulder H; Sundler F
  • Adolescents carrying a missense mutation in the CART gene exhibit increased anxiety and depression.
    Depress Anxiety Volume: 23 Page(s): 90 - 92
    01/01/2006 Authors: Miraglia del Giudice E; Santoro N; Fiumani P; Dominguez G; Kuhar MJ; Perrone L
  • The Leu34Phe ProCART mutation leads to cocaine- and amphetamine-regulated transcript (CART) deficiency: a possible cause for obesity in humans.
    Endocrinology Volume: 147 Page(s): 39 - 43
    01/01/2006 Authors: Yanik T; Dominguez G; Kuhar MJ; Del Giudice EM; Loh YP
  • Cart peptide promotes wake and seizure activity in the rat
    Volume: 29 Page(s): A22 - A22
    01/01/2006 Authors: Keating GL; Kuhar MJ; Vicentic A; Rye DB
  • CART (cocaine- and amphetamine-regulated transcript) peptide receptors: specific binding in AtT20 cells.
    Eur J Pharmacol Volume: 528 Page(s): 188 - 189
    12/28/2005 Authors: Vicentic A; Lakatos A; Kuhar MJ
  • Cocaine-induced alterations in nucleus accumbens ionotropic glutamate receptor subunits in human and non-human primates.
    J Neurochem Volume: 95 Page(s): 1785 - 1793
    12/01/2005 Authors: Hemby SE; Tang W; Muly EC; Kuhar MJ; Howell L; Mash DC
  • Synthesis and monoamine transporter binding properties of 2,3-diaryltropanes.
    J Med Chem Volume: 48 Page(s): 7437 - 7444
    11/17/2005 Authors: Kotturi SV; Jiang S; Chang A-C; Abraham P; Navarro HA; Kuhar MJ; Carroll FI
  • Cocaine- and amphetamine-regulated transcript peptides play a role in drug abuse and are potential therapeutic targets.
    AAPS J Volume: 7 Page(s): E259 - E265
    09/02/2005 Authors: Kuhar MJ; Jaworski JN; Hubert GW; Philpot KB; Dominguez G
  • Cocaine- and amphetamine-regulated transcript (CART) peptide activates the extracellular signal-regulated kinase (ERK) pathway in AtT20 cells via putative G-protein coupled receptors.
    Neurosci Lett Volume: 384 Page(s): 198 - 202
    08/12/2005 Authors: Lakatos A; Prinster S; Vicentic A; Hall RA; Kuhar MJ
  • Effects of early maternal separation on ethanol intake, GABA receptors and metabolizing enzymes in adult rats.
    Psychopharmacology (Berl) Volume: 181 Page(s): 8 - 15
    08/01/2005 Authors: Jaworski JN; Francis DD; Brommer CL; Morgan ET; Kuhar MJ
  • Colocalization of CART with substance P but not enkephalin in the rat nucleus accumbens.
    Brain Res Volume: 1050 Page(s): 8 - 14
    07/19/2005 Authors: Hubert GW; Kuhar MJ
  • CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight.
    Regul Pept Volume: 129 Page(s): 203 - 211
    07/15/2005 Authors: Wierup N; Richards WG; Bannon AW; Kuhar MJ; Ahrn B; Sundler F
  • The effects of cocaine on CART expression in the rat nucleus accumbens: a possible role for corticosterone.
    Eur J Pharmacol Volume: 517 Page(s): 45 - 50
    07/04/2005 Authors: Hunter RG; Vicentic A; Rogge G; Kuhar MJ
  • Species differences in brain distribution of CART mRNA and CART peptide between prairie and meadow voles.
    Brain Res Volume: 1048 Page(s): 12 - 23
    06/28/2005 Authors: Hunter RG; Lim MM; Philpot KB; Young LJ; Kuhar MJ
  • Synthesis and monoamine transporter binding properties of 3alpha-(substituted phenyl)nortropane-2beta-carboxylic acid methyl esters. Norepinephrine transporter selective compounds.
    J Med Chem Volume: 48 Page(s): 3852 - 3857
    06/02/2005 Authors: Carroll FI; Tyagi S; Blough BE; Kuhar MJ; Navarro HA
  • Synthesis and monoamine transporter binding properties of 3beta-(3',4'-disubstituted phenyl)tropane-2beta-carboxylic acid methyl esters.
    J Med Chem Volume: 48 Page(s): 2767 - 2771
    04/21/2005 Authors: Carroll FI; Blough BE; Nie Z; Kuhar MJ; Howell LL; Navarro HA
  • Synthesis, structural identification, and ligand binding of tropane ring analogs of paroxetine and an unexpected aza-bicyclo[3.2.2]nonane rearrangement product.
    Bioorg Med Chem Volume: 13 Page(s): 2439 - 2449
    04/01/2005 Authors: Runyon SP; Burgess JP; Abraham P; Keverline-Frantz KI; Flippen-Anderson J; Deschamps J; Lewin AH; Navarro HA; Boja JW; Kuhar MJ
  • CART receptor is coupled to Gi/o protein and MAP kinase activation in AtT20 cells
    Volume: 19 Page(s): A1548 - A1548
    03/07/2005 Authors: Lakatos A; Vicentic A; Hall RA; Prinster S; Kuhar MJ
  • CART expression in the rat nucleus accumbens is regulated by the PKA/CREB pathway
    Volume: 19 Page(s): A509 - A509
    03/04/2005 Authors: Jones DC; Kuhar MJ
  • CART peptide identification in monkey and human CSF
    Volume: 19 Page(s): A509 - A509
    03/04/2005 Authors: Vicentic A; Dominguez G; Rye D; Kuhar M
  • Effect of corticosterone on CART peptide levels in rat blood.
    Peptides Volume: 26 Page(s): 531 - 533
    03/01/2005 Authors: Vicentic A; Hunter RG; Kuhar MJ
  • CART peptide diurnal rhythm in brain and effect of fasting.
    Brain Res Volume: 1032 Page(s): 111 - 115
    01/25/2005 Authors: Vicentic A; Lakatos A; Hunter R; Philpot K; Dominguez G; Kuhar MJ
  • Synthesis and ligand binding of tropane ring analogues of paroxetine (vol 41, pg 247, 2004)
    JOURNAL OF MEDICINAL CHEMISTRY Volume: 48 Page(s): 336 - 336
    01/13/2005 Authors: Keverline-Frantz KI; Boja JW; Kuhar MJ; Abraham P; Burgess JP; Lewin AH; Carroll FI
  • Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide.
    Neuroendocrinology Volume: 81 Page(s): 273 - 282
    01/01/2005 Authors: Osei-Hyiaman D; Depetrillo M; Harvey-White J; Bannon AW; Cravatt BF; Kuhar MJ; Mackie K; Palkovits M; Kunos G
  • A cocaine-and-amphetamine-regulated-transcript peptide projection from the lateral hypothalamus to the ventral tegmental area.
    Neuroscience Volume: 135 Page(s): 915 - 925
    01/01/2005 Authors: Philpot KB; Dallvechia-Adams S; Smith Y; Kuhar MJ
  • Monoamine transporter binding, locomotor activity, and drug discrimination properties of 3-(4-substituted-phenyl)tropane-2-carboxylic acid methyl ester isomers.
    J Med Chem Volume: 47 Page(s): 6401 - 6409
    12/02/2004 Authors: Carroll FI; Runyon SP; Abraham P; Navarro H; Kuhar MJ; Pollard GT; Howard JL
  • CART peptide levels are altered by a mutation associated with obesity at codon 34.
    Mol Psychiatry Volume: 9 Page(s): 1065 - 1066
    12/01/2004 Authors: Dominguez G; del Giudice EM; Kuhar MJ
  • CART in feeding and obesity.
    Trends Endocrinol Metab Volume: 15 Page(s): 454 - 459
    11/01/2004 Authors: Hunter RG; Philpot K; Vicentic A; Dominguez G; Hubert GW; Kuhar MJ
  • Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice.
    Brain Res Volume: 1024 Page(s): 146 - 149
    10/22/2004 Authors: Damaj MI; Hunter RG; Martin BR; Kuhar MJ
  • CART peptides: modulators of mesolimbic dopamine, feeding, and stress.
    Ann N Y Acad Sci Volume: 1025 Page(s): 363 - 369
    10/01/2004 Authors: Dominguez G; Vicentic A; Del Giudice EM; Jaworski J; Hunter RG; Kuhar MJ
  • CART peptide: central mediator of leptin-induced adipose tissue apoptosis?
    Regul Pept Volume: 121 Page(s): 155 - 162
    09/15/2004 Authors: Choi Y-H; Della-Fera MA; Li C; Hartzell DL; Little DE; Kuhar MJ; Baile CA
  • Cocaine- and amphetamine-regulated transcript peptide levels in blood exhibit a diurnal rhythm: regulation by glucocorticoids.
    Endocrinology Volume: 145 Page(s): 4119 - 4124
    09/01/2004 Authors: Vicentic A; Dominguez G; Hunter RG; Philpot K; Wilson M; Kuhar MJ
  • Transcriptional regulation of the CART promoter in CATH.a cells.
    Brain Res Mol Brain Res Volume: 126 Page(s): 22 - 29
    07/05/2004 Authors: Dominguez G; Kuhar MJ
  • Differential CART mRNA expression between prairie and meadow voles: A role in pair-bonding?
    Volume: 46 Page(s): 99 - 99
    06/01/2004 Authors: Philpot KB; Hunter RG; Lim MM; Young LJ; Kuhar MJ
  • Cocaine- and amphetamine-regulated transcript peptide in the rat anterior pituitary gland is localized in gonadotrophs and suppresses prolactin secretion.
    Endocrinology Volume: 145 Page(s): 2542 - 2550
    05/01/2004 Authors: Kuriyama G; Takekoshi S; Tojo K; Nakai Y; Kuhar MJ; Osamura RY
  • CART peptide levels in the brain exhibit a diurnal rhythm and are influenced by fasting
    Volume: 18 Page(s): A574 - A574
    03/23/2004 Authors: Vicentic A; Hunter R; Philpot K; Dominguez G; Kuhar M
  • CART mRNA in the rat nucleus accumbens is down-regulated via D3 dopamine receptors
    Volume: 18 Page(s): A209 - A209
    03/23/2004 Authors: Hunter RG; Kuhar MJ
  • Cocaine- and amphetamine-regulated transcript (CART) is expressed in several islet cell types during rat development.
    J Histochem Cytochem Volume: 52 Page(s): 169 - 177
    02/01/2004 Authors: Wierup N; Kuhar M; Nilsson BO; Mulder H; Ekblad E; Sundler F
  • Synthesis, monoamine transporter binding properties, and behavioral pharmacology of a series of 3beta-(substituted phenyl)-2beta-(3'-substituted isoxazol-5-yl)tropanes.
    J Med Chem Volume: 47 Page(s): 296 - 302
    01/15/2004 Authors: Carroll FI; Pawlush N; Kuhar MJ; Pollard GT; Howard JL
  • Intra-accumbal injection of CART (cocaine-amphetamine regulated transcript) peptide reduces cocaine-induced locomotor activity.
    J Pharmacol Exp Ther Volume: 307 Page(s): 1038 - 1044
    12/01/2003 Authors: Jaworski JN; Kozel MA; Philpot KB; Kuhar MJ
  • Cocaine- and amphetamine-regulated transcript: distribution and function in rat gastrointestinal tract.
    Neurogastroenterol Motil Volume: 15 Page(s): 545 - 557
    10/01/2003 Authors: Ekblad E; Kuhar M; Wierup N; Sundler F
  • Effects of adrenalectomy on CART expression in the rat arcuate nucleus.
    Synapse Volume: 50 Page(s): 14 - 19
    10/01/2003 Authors: Balkan B; Koylu E; Pogun S; Kuhar MJ
  • Antinociceptive effects of supraspinal rat cart (55-102) peptide in mice.
    Brain Res Volume: 983 Page(s): 233 - 236
    09/05/2003 Authors: Damaj MI; Martin BR; Kuhar MJ
  • Is the onset of psychoactive drug effects compatible with a protein-synthesis mechanism?
    Neuropsychopharmacology Volume: 28 Suppl 1 Page(s): S94 - S97
    07/01/2003 Authors: Kuhar MJ; Joyce AR
  • CART peptides are modulators of mesolimbic dopamine and psychostimulants.
    Life Sci Volume: 73 Page(s): 741 - 747
    06/27/2003 Authors: Jaworski JN; Vicentic A; Hunter RG; Kimmel HL; Kuhar MJ
  • CART peptides as targets for CNS drug development.
    Curr Drug Targets CNS Neurol Disord Volume: 2 Page(s): 201 - 205
    06/01/2003 Authors: Hunter RG; Kuhar MJ
  • CART peptides in drug abuse and dependence
    Volume: 13 Page(s): S20 - S21
    03/01/2003 Authors: Hunter RG; Jaworski JN; Dominguez G; Kuhar MJ
  • Withdrawal from repeated cocaine alters dopamine transporter protein turnover in the rat striatum.
    J Pharmacol Exp Ther Volume: 304 Page(s): 15 - 21
    01/01/2003 Authors: Kimmel HL; Carroll FI; Kuhar MJ
  • Synthesis and transporter binding properties of 3beta-[4'-(phenylalkyl, -phenylalkenyl, and -phenylalkynyl)phenyl]tropane-2beta-carboxylic acid methyl esters: evidence of a remote phenyl binding domain on the dopamine transporter.
    J Med Chem Volume: 45 Page(s): 4029 - 4037
    08/29/2002 Authors: Blough BE; Keverline KI; Nie Z; Navarro H; Kuhar MJ; Carroll FI
  • Synthesis and pharmacology of potential site specific cocaine abuse treatment agents: Exploration of a secondary phenyl group interaction at the dopamine transporter.
    Volume: 224 Page(s): U52 - U52
    08/18/2002 Authors: Coons S; Javanmard S; Deutsch HM; Collard DM; Schweri MM; Kuhar MJ
  • CART promoter CRE site binds phosphorylated CREB.
    Brain Res Mol Brain Res Volume: 104 Page(s): 81 - 85
    07/15/2002 Authors: Lakatos A; Dominguez G; Kuhar MJ
  • Cocaine- and amphetamine-regulated transcript peptide projections in the ventral midbrain: colocalization with gamma-aminobutyric acid, melanin-concentrating hormone, dynorphin, and synaptic interactions with dopamine neurons.
    J Comp Neurol Volume: 448 Page(s): 360 - 372
    07/08/2002 Authors: Dallvechia-Adams S; Kuhar MJ; Smith Y
  • Synthesis and pharmacology of site specific cocaine abuse treatment agents: 5-and 6-substituted trans-2-aminomethyl-3-(4-chloro)-phenylbicyclo[2.2.2]octanes and 2-amino-3-(4-chloro)-phenylbicyclo[2.2.2]octanes.
    Volume: 223 Page(s): A96 - A96
    04/07/2002 Authors: Javanmard S; Deutsch HM; Collard DM; Kuhar MJ; Schweri MM
  • Characterization of the cocaine- and amphetamine-regulated transcript (CART) peptide gene promoter and its activation by a cyclic AMP-dependent signaling pathway in GH3 cells.
    J Neurochem Volume: 80 Page(s): 885 - 893
    03/01/2002 Authors: Dominguez G; Lakatos A; Kuhar MJ
  • Social rank and vulnerability to drug abuse.
    Nat Neurosci Volume: 5 Page(s): 88 - 90
    02/01/2002 Authors: Kuhar MJ
  • CART peptides.
    Neuropeptides Volume: 36 Page(s): 1 - 8
    02/01/2002 Authors: Kuhar MJ; Adams S; Dominguez G; Jaworski J; Balkan B
  • Activity of various CART peptides in changing locomotor activity in the rat.
    Neuropeptides Volume: 36 Page(s): 9 - 12
    02/01/2002 Authors: Kimmel HL; Thim L; Kuhar MJ
  • Locomotor stimulant effects of novel phenyltropanes in the mouse.
    Drug Alcohol Depend Volume: 65 Page(s): 25 - 36
    12/01/2001 Authors: Kimmel HL; Carroll FI; Kuhar MJ
  • The effect of adrenalectomy on cocaine and amphetamine-regulated transcript (CART) expression in the hypothalamic nuclei of the rat.
    Brain Res Volume: 917 Page(s): 15 - 20
    10/26/2001 Authors: Balkan B; Koylu EO; Kuhar MJ; Pogun S
  • Slow onset of CNS drugs: can changes in protein concentration account for the delay?
    Trends Pharmacol Sci Volume: 22 Page(s): 450 - 456
    09/01/2001 Authors: Kuhar MJ; Joyce AR
  • [(125)I]3beta-(4-ethyl-3-iodophenyl)nortropane-2beta-carboxylic acid methyl ester ([(125)I]EINT): a potent and selective radioligand for the brain serotonin transporter.
    Synapse Volume: 41 Page(s): 241 - 247
    09/01/2001 Authors: Navarro HA; Xu H; Zhong D; Blough BE; Ross WP; Kuhar MJ; Carroll FI
  • Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission.
    J Neurosci Volume: 21 Page(s): 6338 - 6347
    08/15/2001 Authors: Wu Q; Reith ME; Kuhar MJ; Carroll FI; Garris PA
  • Anticocaine catalytic antibodies have no affinity for RTI compounds: implications for treatment.
    Synapse Volume: 41 Page(s): 176 - 178
    08/01/2001 Authors: Kuhar MJ; Carroll FI; Bharat N; Landry DW
  • Dopamine D1 and D2 receptors influence dopamine transporter synthesis and degradation in the rat.
    J Pharmacol Exp Ther Volume: 298 Page(s): 129 - 140
    07/01/2001 Authors: Kimmel HL; Joyce AR; Carroll FI; Kuhar MJ
  • Intracerebroventricular CART peptide reduces rat ingestive behavior and alters licking microstructure.
    Am J Physiol Regul Integr Comp Physiol Volume: 280 Page(s): R1613 - R1619
    06/01/2001 Authors: Aja S; Schwartz GJ; Kuhar MJ; Moran TH
  • CART peptide-immunoreactive projection from the nucleus accumbens targets substantia nigra pars reticulata neurons in the rat.
    J Comp Neurol Volume: 434 Page(s): 29 - 39
    05/21/2001 Authors: Dallvechia-Adams S; Smith Y; Kuhar MJ
  • Regenerating optic fibers correct large-scale errors by random growth: evidence from in vivo imaging.
    J Comp Neurol Volume: 434 Page(s): 40 - 55
    05/21/2001 Authors: Dawson AJ; Meyer RL
  • In vitro autoradiography.
    Curr Protoc Pharmacol Volume: Chapter 8 Page(s): Unit - 8.1
    05/01/2001 Authors: Kuhar MJ
  • Genes in drug abuse.
    Drug Alcohol Depend Volume: 62 Page(s): 157 - 162
    05/01/2001 Authors: Kuhar MJ; Joyce A; Dominguez G
  • Neurotransmitter transporters synthesis and degradation rates.
    Life Sci Volume: 68 Page(s): 2181 - 2185
    04/06/2001 Authors: Kimmel H; Vicentic A; Kuhar MJ
  • RTI-76, an irreversible inhibitor of dopamine transporter binding, increases locomotor activity in the rat at high doses.
    Brain Res Volume: 897 Page(s): 157 - 163
    04/06/2001 Authors: Kimmel HL; Carroll FI; Kuhar MJ
  • Characterization of CART neurons in the rat and human hypothalamus.
    J Comp Neurol Volume: 432 Page(s): 1 - 19
    03/26/2001 Authors: Elias CF; Lee CE; Kelly JF; Ahima RS; Kuhar M; Saper CB; Elmquist JK
  • Actions of cocaine- and amphetamine-regulated transcript (CART) peptide on regulation of appetite and hypothalamo-pituitary axes in vitro and in vivo in male rats.
    Brain Res Volume: 893 Page(s): 186 - 194
    03/02/2001 Authors: Stanley SA; Small CJ; Murphy KG; Rayes E; Abbott CR; Seal LJ; Morgan DG; Sunter D; Dakin CL; Kim MS
  • Association of cocaine- and amphetamine-regulated transcript-immunoreactive elements with thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and its role in the regulation of the hypothalamic-pituitary-thyroid axis during fasting.
    J Neurosci Volume: 20 Page(s): 9224 - 9234
    12/15/2000 Authors: Fekete C; Mihly E; Luo LG; Kelly J; Clausen JT; Mao Q; Rand WM; Moss LG; Kuhar M; Emerson CH
  • Hypothalamic CART and serum leptin levels are reduced in the anorectic (anx/anx) mouse.
    Brain Res Mol Brain Res Volume: 84 Page(s): 97 - 105
    12/08/2000 Authors: Johansen JE; Broberger C; Lavebratt C; Johansson C; Kuhar MJ; Hkfelt T; Schalling M
  • 3alpha-(4-Substituted phenyl)nortropane-2beta-carboxylic acid methyl esters show selective binding at the norepinephrine transporter.
    Bioorg Med Chem Lett Volume: 10 Page(s): 2445 - 2447
    11/06/2000 Authors: Blough BE; Holmquist CR; Abraham P; Kuhar MJ; Carroll FI
  • RTI-76, an isothiocyanate derivative of a phenyltropane cocaine analog, as a tool for irreversibly inactivating dopamine transporter function in vitro.
    Naunyn Schmiedebergs Arch Pharmacol Volume: 362 Page(s): 238 - 247
    09/01/2000 Authors: Wang LC; Berfield JL; Kuhar MJ; Carroll FI; Reith ME
  • Quantification and synthesis of cocaine- and amphetamine-regulated transcript peptide (79-102)-like immunoreactivity and mRNA in rat tissues.
    J Endocrinol Volume: 166 Page(s): 659 - 668
    09/01/2000 Authors: Murphy KG; Abbott CR; Mahmoudi M; Hunter R; Gardiner JV; Rossi M; Stanley SA; Ghatei MA; Kuhar MJ; Bloom SR
  • Intra-ventral tegmental area injection of rat cocaine and amphetamine-regulated transcript peptide 55-102 induces locomotor activity and promotes conditioned place preference.
    J Pharmacol Exp Ther Volume: 294 Page(s): 784 - 792
    08/01/2000 Authors: Kimmel HL; Gong W; Vechia SD; Hunter RG; Kuhar MJ
  • Co-localization of cart peptide immunoreactivity and nitric oxide synthase activity in rat hypothalamus.
    Brain Res Volume: 868 Page(s): 352 - 357
    06/23/2000 Authors: Koylu EO; Weruaga E; Balkan B; Alonso JR; Kuhar MJ; Pogun S
  • CART peptides.
    Regul Pept Volume: 89 Page(s): 1 - 6
    05/10/2000 Authors: Kuhar MJ; Adams LD; Hunter RG; Vechia SD; Smith Y
  • Dopamine transporter synthesis and degradation rate in rat striatum and nucleus accumbens using RTI-76.
    Neuropharmacology Volume: 39 Page(s): 578 - 585
    02/14/2000 Authors: Kimmel HL; Carroll FI; Kuhar MJ
  • Comparative behavioral pharmacology of cocaine and the selective dopamine uptake inhibitor RTI-113 in the squirrel monkey.
    J Pharmacol Exp Ther Volume: 292 Page(s): 521 - 529
    02/01/2000 Authors: Howell LL; Czoty PW; Kuhar MJ; Carrol FI
  • CART peptide immunoreactivity in the hypothalamus and pituitary in monkeys: analysis of ultrastructural features and synaptic connections in the paraventricular nucleus.
    J Comp Neurol Volume: 416 Page(s): 291 - 308
    01/17/2000 Authors: Dall Vechia S; Lambert PD; Couceyro PC; Kuhar MJ; Smith Y
  • CART: from gene to function.
    Brain Res Volume: 848 Page(s): 137 - 140
    11/27/1999 Authors: Adams LD; Gong W; Vechia SD; Hunter RG; Kuhar MJ
  • CART peptides and feeding
    Volume: 848 Page(s): A19 - A19
    11/27/1999 Authors: Kuhar MJ; Gong W; Adams L; Dall Vechia S; Hunter R; Elmquist J
  • Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-substituted-6-amino-5-phenylbicyclo[2.2.2]octanes.
    J Med Chem Volume: 42 Page(s): 4836 - 4843
    11/18/1999 Authors: Javanmard S; Deutsch HM; Collard DM; Kuhar MJ; Schweri MM
  • Cocaine- and amphetamine-regulated transcript in the rat vagus nerve: A putative mediator of cholecystokinin-induced satiety.
    Proc Natl Acad Sci U S A Volume: 96 Page(s): 13506 - 13511
    11/09/1999 Authors: Broberger C; Holmberg K; Kuhar MJ; Hkfelt T
  • Neuropeptide Y innervation and neuropeptide-Y-Y1-receptor-expressing neurons in the paraventricular hypothalamic nucleus of the mouse.
    Neuroendocrinology Volume: 70 Page(s): 295 - 305
    11/01/1999 Authors: Broberger C; Visser TJ; Kuhar MJ; Hkfelt T
  • Serotonin transporter production and degradation rates: studies with RTI-76.
    Brain Res Volume: 841 Page(s): 1 - 10
    09/11/1999 Authors: Vicentic A; Battaglia G; Carroll FI; Kuhar MJ
  • CART peptide analysis by Western blotting.
    Synapse Volume: 33 Page(s): 163 - 171
    09/01/1999 Authors: Kuhar MJ; Yoho LL
  • 2-substituted-6-amino-5-phenyl bicyclo[2.2.2]octanes as monoamine uptake inhibitors.
    Volume: 218 Page(s): U975 - U975
    08/22/1999 Authors: Deutsch HM; Collard DM; Javanmard S; Holtzman SG; Spealman RD; Kuhar MJ; Schweri MM
  • Studies of selected phenyltropanes at monoamine transporters.
    Drug Alcohol Depend Volume: 56 Page(s): 9 - 15
    08/02/1999 Authors: Kuhar MJ; McGirr KM; Hunter RG; Lambert PD; Garrett BE; Carroll FI
  • Chronic lithium treatment decreases neuronal activity in the nucleus accumbens and cingulate cortex of the rat.
    Neuropsychopharmacology Volume: 21 Page(s): 229 - 237
    08/01/1999 Authors: Lambert PD; McGirr KM; Ely TD; Kilts CD; Kuhar MJ
  • Pharmacotherapies for treatment of cocaine abuse: preclinical aspects.
    J Med Chem Volume: 42 Page(s): 2721 - 2736
    07/29/1999 Authors: Carroll FI; Howell LL; Kuhar MJ
  • Cholinergic axon terminals in the ventral tegmental area target a subpopulation of neurons expressing low levels of the dopamine transporter.
    J Comp Neurol Volume: 410 Page(s): 197 - 210
    07/26/1999 Authors: Garzn M; Vaughan RA; Uhl GR; Kuhar MJ; Pickel VM
  • CART peptides: novel addiction- and feeding-related neuropeptides.
    Trends Neurosci Volume: 22 Page(s): 316 - 320
    07/01/1999 Authors: Kuhar MJ; Dall Vechia SE
  • CART peptide-immunoreactive neurones in the nucleus accumbens in monkeys: ultrastructural analysis, colocalization studies, and synaptic interactions with dopaminergic afferents.
    J Comp Neurol Volume: 407 Page(s): 491 - 511
    05/17/1999 Authors: Smith Y; Kieval J; Couceyro PR; Kuhar MJ
  • Dopamine transporter changes in cocaine users following one month abstinence.
    Volume: 40 Page(s): 109P - 109P
    05/01/1999 Authors: Wong DF; Rothman RB; Contoreggi C; Yokoi F; Stephane M; Dogan S; Schretlen D; Kuhar M; Gjedde A
  • CART peptides colocalize with tyrosine hydroxylase neurons in rat locus coeruleus.
    Synapse Volume: 31 Page(s): 309 - 311
    03/15/1999 Authors: Koylu EO; Smith Y; Couceyro PR; Kuhar MJ
  • Comparative studies of epibatidine derivatives [18F]NFEP and [18F]N-methyl-NFEP: kinetics, nicotine effect, and toxicity.
    Nucl Med Biol Volume: 26 Page(s): 139 - 148
    01/01/1999 Authors: Ding YS; Molina PE; Fowler JS; Logan J; Volkow ND; Kuhar MJ; Carroll FI
  • Synthesis and transporter binding properties of (R)-2 beta, 3 beta- and (R)-2 alpha, 3 alpha-diaryltropanes.
    Bioorg Med Chem Lett Volume: 8 Page(s): 3689 - 3692
    12/15/1998 Authors: Jiang S; Chang AC; Abraham P; Kuhar MJ; Carroll FI
  • Leptin activates hypothalamic CART neurons projecting to the spinal cord.
    Neuron Volume: 21 Page(s): 1375 - 1385
    12/01/1998 Authors: Elias CF; Lee C; Kelly J; Aschkenasi C; Ahima RS; Couceyro PR; Kuhar MJ; Saper CB; Elmquist JK
  • RTI-113 administration reduces cocaine self-administration at high occupancy of dopamine transporter.
    Synapse Volume: 30 Page(s): 49 - 55
    09/01/1998 Authors: Dworkin SI; Lambert P; Sizemore GM; Carroll FI; Kuhar MJ
  • Multiple binding sites for [125I]RTI-121 and other cocaine analogs in rat frontal cerebral cortex.
    Synapse Volume: 30 Page(s): 9 - 17
    09/01/1998 Authors: Boja JW; Carroll FI; Vaughan RA; Kopajtic T; Kuhar MJ
  • Cocaine- and amphetamine-regulated transcript (CART) peptide immunoreactivity in myenteric plexus neurons of the rat ileum and co-localization with choline acetyltransferase.
    Synapse Volume: 30 Page(s): 1 - 8
    09/01/1998 Authors: Couceyro P; Paquet M; Koylu E; Kuhar MJ; Smith Y
  • CART peptides in the central control of feeding and interactions with neuropeptide Y.
    Synapse Volume: 29 Page(s): 293 - 298
    08/01/1998 Authors: Lambert PD; Couceyro PR; McGirr KM; Dall Vechia SE; Smith Y; Kuhar MJ
  • Dopamine D-2 receptor-mediated regulation of central cholinergic activity: PET studies with [F-18]fluoroepibatidine.
    Volume: 39 Page(s): 12P - 12P
    05/01/1998 Authors: Ding YS; Fowler JS; Volkow ND; Logan J; Dewey SL; Carroll FI; Kuhar MJ
  • Effect of dental adhesive coat on the permeability of the ground or acid-etched dental enamel.
    Volume: 77 Page(s): 1231 - 1231
    05/01/1998 Authors: Kuhar M; Cevc P; Funduk N
  • Cocaine- and amphetamine-regulated transcript peptide immunohistochemical localization in the rat brain.
    J Comp Neurol Volume: 391 Page(s): 115 - 132
    02/02/1998 Authors: Koylu EO; Couceyro PR; Lambert PD; Kuhar MJ
  • Parkinsonian patients report blunted subjective effects of methylphenidate.
    Exp Clin Psychopharmacol Volume: 6 Page(s): 54 - 63
    02/01/1998 Authors: Persico AM; Reich S; Henningfield JE; Kuhar MJ; Uhl GR
  • Synthesis and ligand binding of tropane ring analogues of paroxetine.
    J Med Chem Volume: 41 Page(s): 247 - 257
    01/15/1998 Authors: Keverline-Frantz KI; Boja JW; Kuhar MJ; Abraham P; Burgess JP; Lewin AH; Carroll FI
  • Dopamine transporter changes in neuropsychiatric disorders.
    Adv Pharmacol Volume: 42 Page(s): 219 - 223
    01/01/1998 Authors: Wong DF; Ricaurte G; Grnder G; Rothman R; Naidu S; Singer H; Harris J; Yokoi F; Villemagne V; Szymanski S
  • Recent biochemical studies of the dopamine transporter--a CNS drug target.
    Life Sci Volume: 62 Page(s): 1573 - 1575
    01/01/1998 Authors: Kuhar MJ
  • Phosphorylation of dopamine transporters and rapid adaptation to cocaine.
    Adv Pharmacol Volume: 42 Page(s): 1042 - 1045
    01/01/1998 Authors: Vaughan RA; Huff RA; Uhl GR; Kuhar MJ
  • Localization of dopamine transporter protein by microscopic histochemistry.
    Adv Pharmacol Volume: 42 Page(s): 168 - 170
    01/01/1998 Authors: Kuhar MJ; Vaughan R; Uhl G; Cerruti C; Revay R; Freed C; Nirenburg M; Pickel V
  • 3 beta-phenyl-2 beta-substituted tropanes - An SAR analysis
    MEDICINAL CHEMISTRY RESEARCH Volume: 8 Page(s): 59 - 65
    01/01/1998 Authors: Carroll FI; Lewin AH; Kuhar MJ
  • 3 Beta-(4-ethyl-3-iodophenyl)nortropane-2 beta-carboxylic acid methyl ester as a high-affinity selective ligand for the serotonin transporter.
    J Med Chem Volume: 40 Page(s): 3861 - 3864
    11/21/1997 Authors: Blough BE; Abraham P; Mills AC; Lewin AH; Boja JW; Scheffel U; Kuhar MJ; Carroll FI
  • Immunohistochemical localization of novel CART peptides in rat hypothalamus, pituitary and adrenal gland.
    J Neuroendocrinol Volume: 9 Page(s): 823 - 833
    11/01/1997 Authors: Koylu EO; Couceyro PR; Lambert PD; Ling NC; DeSouza EB; Kuhar MJ
  • Fluoro-norchloroepibatidine: preclinical assessment of acute toxicity.
    Nucl Med Biol Volume: 24 Page(s): 743 - 747
    11/01/1997 Authors: Molina PE; Ding YS; Carroll FI; Liang F; Volkow ND; Pappas N; Kuhar M; Abumrad N; Gatley SJ; Fowler JS
  • The dopamine transporter: comparative ultrastructure of dopaminergic axons in limbic and motor compartments of the nucleus accumbens.
    J Neurosci Volume: 17 Page(s): 6899 - 6907
    09/15/1997 Authors: Nirenberg MJ; Chan J; Pohorille A; Vaughan RA; Uhl GR; Kuhar MJ; Pickel VM
  • Ultrastructural localization of CART (cocaine- and amphetamine-regulated transcript) peptides in the nucleus accumbens of monkeys.
    Synapse Volume: 27 Page(s): 90 - 94
    09/01/1997 Authors: Smith Y; Koylu EO; Couceyro P; Kuhar MJ
  • Cocaine self-administration alters brain NADH dehydrogenase mRNA levels.
    Neuroreport Volume: 8 Page(s): 2437 - 2441
    07/28/1997 Authors: Couceyro P; Shoaib M; McCoy M; Goldberg SR; Kuhar MJ
  • Synthesis and nicotinic acetylcholine receptor binding properties of exo-2-(2'-fluoro-5'-pyridinyl)-7-azabicyclo-[2.2.1]heptane: a new positron emission tomography ligand for nicotinic receptors.
    J Med Chem Volume: 40 Page(s): 2293 - 2295
    02/01/1997 Authors: Liang F; Navarro HA; Abraham P; Kotian P; Ding YS; Fowler J; Volkow N; Kuhar MJ; Carroll FI
  • Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area.
    J Neurosci Volume: 17 Page(s): 5255 - 5262
    07/15/1997 Authors: Nirenberg MJ; Chan J; Vaughan RA; Uhl GR; Kuhar MJ; Pickel VM
  • Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes.
    J Biol Chem Volume: 272 Page(s): 15541 - 15546
    06/13/1997 Authors: Vaughan RA; Huff RA; Uhl GR; Kuhar MJ
  • Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area.
    J Neurosci Volume: 17 Page(s): 4037 - 4044
    06/01/1997 Authors: Nirenberg MJ; Chan J; Vaughan RA; Uhl GR; Kuhar MJ; Pickel VM
  • [F-18]norchlorofluorepibatidine (NFED): Preclinical toxicological studies.
    Volume: 38 Page(s): 1209 - 1209
    05/01/1997 Authors: Molina P; Ding YS; Carroll FI; Liang F; Volkow N; Kuhar M; Pappas N; King P; Abumrad N; Fowler JS
  • Further studies on the anatomical distribution of CART by in situ hybridization.
    J Chem Neuroanat Volume: 12 Page(s): 229 - 241
    05/01/1997 Authors: Couceyro PR; Koylu EO; Kuhar MJ
  • Antihistamine responsive cluster headache in a teenaged girl.
    Headache Volume: 37 Page(s): 296 - 298
    05/01/1997 Authors: Neubauer D; Kuhar M; Ravnik IM
  • Dopamine transporter occupancy by RTI-55, inhibition of dopamine transport and stimulation of locomotor activity
    Volume: 38 Page(s): 222 - 222
    05/01/1997 Authors: Gatley SJ; Gifford AN; Volkow ND; Fowler JS; Kuhar MJ; Carroll FI
  • PET studies of [18F]norchlorofluoroepibatidine in mapping nicotinic acetylcholine receptors (nAChR).
    Volume: 38 Page(s): 295 - 295
    05/01/1997 Authors: Ding YS; Fowler JS; Gatley SJ; Volkow ND; Logan J; Dewey SL; Liang F; Carroll FI; Kuhar MJ
  • 3 alpha-(substituted phenyl)tropane-2 beta-carboxylic acid esters: Ligands with unexpectedly high affinity and selectivity at the dopamine transporter.
    Volume: 213 Page(s): 191 - MEDI
    04/13/1997 Authors: Holmquist CR; KeverlineFrantz KI; Abraham P; Boja JW; Kuhar MJ; Carroll FI
  • Synthesis and transporter binding properties of 2,3-diphenyltropane stereoisomers. Comparison to 3beta-phenyltropane-2beta-carboxylic acid esters.
    J Med Chem Volume: 40 Page(s): 1247 - 1251
    04/11/1997 Authors: Chang AC; Burgess JP; Mascarella SW; Abraham P; Kuhar MJ; Carroll FI
  • RTI-352: a 3 alpha analogue of RTI-55 as an in vivo dopamine transporter binding ligand.
    Synapse Volume: 25 Page(s): 389 - 392
    04/01/1997 Authors: Zhan Y; Saindane AM; Scheffel U; Carroll FI; Holmquist CR; Kepler JA; Taylor GF; Kuhar MJ
  • N-substituted phenyltropanes as in vivo binding ligands for rapid imaging studies of the dopamine transporter.
    Synapse Volume: 25 Page(s): 345 - 349
    04/01/1997 Authors: Scheffel U; Lever JR; Abraham P; Parham KR; Mathews WB; Kopajtic T; Carroll FI; Kuhar MJ
  • Quantification of neuroreceptors in the living human brain: IV. Effect of aging and elevations of D2-like receptors in schizophrenia and bipolar illness.
    J Cereb Blood Flow Metab Volume: 17 Page(s): 331 - 342
    03/01/1997 Authors: Wong DF; Pearlson GD; Tune LE; Young LT; Meltzer CC; Dannals RF; Ravert HT; Reith J; Kuhar MJ; Gjedde A
  • Phorbol esters increase dopamine transporter phosphorylation and decrease transport Vmax.
    J Neurochem Volume: 68 Page(s): 225 - 232
    01/01/1997 Authors: Huff RA; Vaughan RA; Kuhar MJ; Uhl GR
  • Cocaine and the dopamine transporter
    Page(s): 207 - 212
    01/01/1997 Authors: Kuhar MJ
  • Halogenated mazindol analogs as potential inhibitors of the cocaine binding site at the dopamine transporter.
    J Med Chem Volume: 39 Page(s): 4935 - 4941
    12/06/1996 Authors: Houlihan WJ; Boja JW; Parrino VA; Kopajtic TA; Kuhar MJ
  • Mapping nicotinic acetylcholine receptors with PET.
    Synapse Volume: 24 Page(s): 403 - 407
    12/01/1996 Authors: Ding YS; Gatley SJ; Fowler JS; Volkow ND; Aggarwal D; Logan J; Dewey SL; Liang F; Carroll FI; Kuhar MJ
  • 3 alpha-(4'-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters: novel ligands with high affinity and selectivity at the dopamine transporter.
    J Med Chem Volume: 39 Page(s): 4139 - 4141
    10/11/1996 Authors: Holmquist CR; Keverline-Frantz KI; Abraham P; Boja JW; Kuhar MJ; Carroll FI
  • Recovery of dopamine transporter binding and function after intrastriatal administration of the irreversible inhibitor RTI-76 [3 beta-(3p-chlorophenyl) tropan-2 beta-carboxylic acid p-isothiocyanatophenylethyl ester hydrochloride].
    J Pharmacol Exp Ther Volume: 279 Page(s): 200 - 206
    10/01/1996 Authors: Fleckenstein AE; Pgn S; Carroll FI; Kuhar MJ
  • Synthesis and transporter binding properties of 3 beta-(4'-alkyl-, 4'-alkenyl-, and 4'-alkynylphenyl)nortropane-2 beta-carboxylic acid methyl esters: serotonin transporter selective analogs.
    J Med Chem Volume: 39 Page(s): 4027 - 4035
    09/27/1996 Authors: Blough BE; Abraham P; Lewin AH; Kuhar MJ; Boja JW; Carroll FI
  • Highly potent cocaine analogs cause long-lasting increases in locomotor activity.
    Eur J Pharmacol Volume: 311 Page(s): 109 - 114
    09/12/1996 Authors: Fleckenstein AE; Kopajtic TA; Boja JW; Carroll FI; Kuhar MJ
  • Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis.
    J Biol Chem Volume: 271 Page(s): 21672 - 21680
    08/30/1996 Authors: Vaughan RA; Kuhar MJ
  • Synthesis, ligand binding, and quantitative structure-activity relationship study of 3 beta-(4'-substituted phenyl)-2 beta-heterocyclic tropanes: evidence for an electrostatic interaction at the 2 beta-position.
    J Med Chem Volume: 39 Page(s): 2753 - 2763
    07/05/1996 Authors: Kotian P; Mascarella SW; Abraham P; Lewin AH; Boja JW; Kuhar MJ; Carroll FI
  • Neurochemical changes in cocaine withdrawal.
    Trends Pharmacol Sci Volume: 17 Page(s): 260 - 264
    07/01/1996 Authors: Kuhar MJ; Pilotte NS
  • Effect of dopaminergic drugs on the in vivo binding of [3H]WIN 35,428 to central dopamine transporters.
    Synapse Volume: 23 Page(s): 61 - 69
    06/01/1996 Authors: Scheffel U; Steinert C; Kim SE; Ehlers MD; Boja JW; Kuhar MJ
  • Dopamine transporters are markedly reduced in Lesch-Nyhan disease in vivo.
    Proc Natl Acad Sci U S A Volume: 93 Page(s): 5539 - 5543
    05/28/1996 Authors: Wong DF; Harris JC; Naidu S; Yokoi F; Marenco S; Dannals RF; Ravert HT; Yaster M; Evans A; Rousset O
  • Species- and brain region-specific dopamine transporters: immunological and glycosylation characteristics.
    J Neurochem Volume: 66 Page(s): 2146 - 2152
    05/01/1996 Authors: Vaughan RA; Brown VL; McCoy MT; Kuhar MJ
  • Evaluation of [11C]RTI-121 as a selective radioligand for PET studies of the dopamine transporter.
    Nucl Med Biol Volume: 23 Page(s): 377 - 384
    04/01/1996 Authors: Hume SP; Luthra SK; Brown DJ; Opacka-Juffry J; Osman S; Ashworth S; Myers R; Brady F; Carroll FI; Kuhar MJ
  • Synthesis and in vivo studies of a selective ligand for the dopamine transporter: 3 beta-(4-[125I]iodophenyl) tropan-2 beta-carboxylic acid isopropyl ester ([125I]RTI-121).
    Nucl Med Biol Volume: 23 Page(s): 277 - 284
    04/01/1996 Authors: Lever JR; Scheffel U; Stathis M; Seltzman HH; Wyrick CD; Abraham P; Parham K; Thomas BF; Boja JW; Kuhar MJ
  • Dopamine transporter immunohistochemistry in median eminence, amygdala, and other areas of the rat brain.
    Synapse Volume: 22 Page(s): 93 - 99
    02/01/1996 Authors: Revay R; Vaughan R; Grant S; Kuhar MJ
  • Displacement of RTI-55 from the dopamine transporter by cocaine.
    Eur J Pharmacol Volume: 296 Page(s): 145 - 151
    01/25/1996 Authors: Gatley SJ; Volkow ND; Chen R; Fowler JS; Carroll FI; Kuhar MJ
  • The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons.
    J Neurosci Volume: 16 Page(s): 436 - 447
    01/15/1996 Authors: Nirenberg MJ; Vaughan RA; Uhl GR; Kuhar MJ; Pickel VM
  • Cocaine withdrawal reduces dopamine transporter binding in the shell of the nucleus accumbens.
    Synapse Volume: 22 Page(s): 87 - 92
    01/01/1996 Authors: Pilotte NS; Sharpe LG; Rountree SD; Kuhar MJ
  • In vivo labeling of neuronal nicotinic acetylcholine receptors with radiolabeled isomers of norchloroepibatidine.
    Neuroreport Volume: 6 Page(s): 2483 - 2488
    12/15/1995 Authors: Scheffel U; Taylor GF; Kepler JA; Carroll FI; Kuhar MJ
  • Development of imaging agents for the dopamine transporter.
    Med Res Rev Volume: 15 Page(s): 419 - 444
    09/01/1995 Authors: Carroll FI; Scheffel U; Dannals RF; Boja JW; Kuhar MJ
  • Synthesis and ligand binding study of 3 beta-(4'-substituted phenyl)-2 beta-(heterocyclic)tropanes.
    J Med Chem Volume: 38 Page(s): 3451 - 3453
    09/01/1995 Authors: Kotian P; Abraham P; Lewin AH; Mascarella SW; Boja JW; Kuhar MJ; Carroll FI
  • Dopamine transporter immunoreactivity in rat brain.
    J Comp Neurol Volume: 359 Page(s): 340 - 349
    08/21/1995 Authors: Freed C; Revay R; Vaughan RA; Kriek E; Grant S; Uhl GR; Kuhar MJ
  • Rate of binding of various inhibitors at the dopamine transporter in vivo.
    Psychopharmacology (Berl) Volume: 119 Page(s): 376 - 384
    06/01/1995 Authors: Stathis M; Scheffel U; Lever SZ; Boja JW; Carroll FI; Kuhar MJ
  • INFLUENCE OF ENAMEL SURFACE ACID-ETCHING AND GRINDING ON MOLECULAR-DIFFUSION
    Volume: 74 Page(s): 944 - 944
    03/01/1995 Authors: KUHAR M; FUNDUK N; CEVC P; SCHARA M
  • Long-lasting inhibition of in vivo cocaine binding to dopamine transporters by 3 beta-(4-iodophenyl)tropane-2-carboxylic acid methyl ester: RTI-55 or beta CIT.
    Synapse Volume: 19 Page(s): 206 - 211
    03/01/1995 Authors: Volkow ND; Gatley SJ; Fowler JS; Chen R; Logan J; Dewey SL; Ding YS; Pappas N; King P; MacGregor RR
  • Cocaine and 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid ester and amide analogues. New high-affinity and selective compounds for the dopamine transporter.
    J Med Chem Volume: 38 Page(s): 379 - 388
    01/20/1995 Authors: Carroll FI; Kotian P; Dehghani A; Gray JL; Kuzemko MA; Parham KA; Abraham P; Lewin AH; Boja JW; Kuhar MJ
  • Developmentally regulated glycosylation of dopamine transporter.
    Brain Res Dev Brain Res Volume: 83 Page(s): 53 - 58
    11/18/1994 Authors: Patel AP; Cerruti C; Vaughan RA; Kuhar MJ
  • Regulation of neurotransmitter reuptake by nitric oxide.
    Ann N Y Acad Sci Volume: 738 Page(s): 305 - 315
    11/17/1994 Authors: Pgn S; Kuhar MJ
  • Synthesis, ligand binding, and QSAR (CoMFA and classical) study of 3 beta-(3'-substituted phenyl)-, 3 beta-(4'-substituted phenyl)-, and 3 beta-(3',4'-disubstituted phenyl)tropane-2 beta-carboxylic acid methyl esters.
    J Med Chem Volume: 37 Page(s): 2865 - 2873
    09/02/1994 Authors: Carroll FI; Mascarella SW; Kuzemko MA; Gao Y; Abraham P; Lewin AH; Boja JW; Kuhar MJ
  • Nitric oxide inhibits 3H-glutamate transport in synaptosomes.
    Synapse Volume: 18 Page(s): 21 - 26
    09/01/1994 Authors: Pogun S; Dawson V; Kuhar MJ
  • Withdrawal of repeated intravenous infusions of cocaine persistently reduces binding to dopamine transporters in the nucleus accumbens of Lewis rats.
    J Pharmacol Exp Ther Volume: 269 Page(s): 963 - 969
    06/01/1994 Authors: Pilotte NS; Sharpe LG; Kuhar MJ
  • EFFECT OF RESERPINE UPON BINDING OF H-3 WIN-35,428 TO DOPAMINE UPTAKE SITES
    Volume: 35 Page(s): P199 - P199
    05/01/1994 Authors: KIM SE; SCHEFFEL U; BOJA JW; KUHAR MJ
  • Secondary amine analogues of 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid esters and N-norcocaine exhibit enhanced affinity for serotonin and norepinephrine transporters.
    J Med Chem Volume: 37 Page(s): 1220 - 1223
    04/15/1994 Authors: Boja JW; Kuhar MJ; Kopajtic T; Yang E; Abraham P; Lewin AH; Carroll FI
  • Occupancy of the serotonin transporter by fluoxetine, paroxetine, and sertraline: in vivo studies with [125I]RTI-55.
    Synapse Volume: 16 Page(s): 263 - 268
    04/01/1994 Authors: Scheffel U; Kim S; Cline EJ; Kuhar MJ
  • DOPAMINE TRANSPORTER AND SYNAPTIC VESICULAR MONOAMINE TRANSPORTER EXPRESSION AND PARKINSONS-DISEASE DOPAMINERGIC DAMAGE
    Volume: 44 Page(s): A282 - A282
    04/01/1994 Authors: UHL GR; SURRATT C; VAUGHN R; KUHAR MJ; MASH D; JAVOYAGID F
  • DOPAMINE TRANSPORTER AND SYNAPTIC VESICULAR MONOAMINE TRANSPORTER EXPRESSION AND PARKINSONS-DISEASE DOPAMINERGIC DAMAGE
    Volume: 44 Page(s): A282 - A282
    04/01/1994 Authors: UHL GR; SURRATT C; VAUGHN R; KUHAR MJ; MASH D; JAVOYAGID F
  • Nitric oxide inhibits [3H]dopamine uptake.
    Brain Res Volume: 641 Page(s): 83 - 91
    03/28/1994 Authors: Pogun S; Baumann MH; Kuhar MJ
  • Reduction in dopamine transporter mRNA after cessation of repeated cocaine administration.
    Brain Res Mol Brain Res Volume: 22 Page(s): 132 - 138
    03/01/1994 Authors: Cerruti C; Pilotte NS; Uhl G; Kuhar MJ
  • Development of PET/SPECT ligands for the serotonin transporter.
    NIDA Res Monogr Volume: 138 Page(s): 111 - 130
    01/01/1994 Authors: Scheffel U; Dannals RF; Suehiro M; Ricaurte GA; Carroll FI; Kuhar MJ; Wagner HN
  • 3-Aryl-2-(3'-substituted-1',2',4'-oxadiazol-5'-yl)tropane analogues of cocaine: affinities at the cocaine binding site at the dopamine, serotonin, and norepinephrine transporters.
    J Med Chem Volume: 36 Page(s): 2886 - 2890
    10/01/1993 Authors: Carroll FI; Gray JL; Abraham P; Kuzemko MA; Lewin AH; Boja JW; Kuhar MJ
  • In vivo imaging of baboon and human dopamine transporters by positron emission tomography using [11C]WIN 35,428.
    Synapse Volume: 15 Page(s): 130 - 142
    10/01/1993 Authors: Wong DF; Yung B; Dannals RF; Shaya EK; Ravert HT; Chen CA; Chan B; Folio T; Scheffel U; Ricaurte GA
  • Potent cocaine analogs inhibit [3H]dopamine uptake in rat mesencephalic cells in primary cultures: pharmacological selectivity of embryonic cocaine sites.
    Brain Res Dev Brain Res Volume: 75 Page(s): 13 - 17
    09/17/1993 Authors: Brouard A; Pelaprat D; Boja JW; Carroll FI; Vial M; Kuhar MJ; Rostene W
  • DOPAMINE TRANSPORTER EXPRESSION CORRELATES WITH PARKINSONS-DISEASE DOPAMINERGIC DAMAGE
    Volume: 34 Page(s): 247 - 247
    08/01/1993 Authors: UHL GR; KITAYAMA S; CERRUTI C; KUHAR MJ; SHIMADA S; MASH D; JAVOYAGID F
  • Species differences in dopamine transporters: postmortem changes and glycosylation differences.
    J Neurochem Volume: 61 Page(s): 496 - 500
    08/01/1993 Authors: Patel A; Uhl G; Kuhar MJ
  • INVIVO DOPAMINE TRANSPORTER SITES IMAGING IN HUMAN USING [C-11] WIN 35,428 POSITRON EMISSION TOMOGRAPHY (PET)
    Volume: 34 Page(s): P197 - P197
    05/01/1993 Authors: YUNG BCK; DANNALS RF; KUHAR MJ; SHAYA EK; RAVERT HT; CHEN C; CHAN B; SCHEFFEL U; RICAURTE G; FOLIO T
  • Recognition of dopamine transporters by antipeptide antibodies.
    Mol Cell Neurosci Volume: 4 Page(s): 209 - 215
    04/01/1993 Authors: Vaughan RA; Uhl G; Kuhar MJ
  • Dopamine transporter mRNA expression is intense in rat midbrain neurons and modest outside midbrain.
    Brain Res Mol Brain Res Volume: 18 Page(s): 181 - 186
    04/01/1993 Authors: Cerruti C; Walther DM; Kuhar MJ; Uhl GR
  • Cocaine receptor: a structure-activity relationship study.
    NIDA Res Monogr Volume: 134 Page(s): 229 - 237
    01/01/1993 Authors: Carroll FI; Lewin AH; Kuhar MJ; Boja JW
  • Neurotransmitter transporters: recent progress.
    Annu Rev Neurosci Volume: 16 Page(s): 73 - 93
    01/01/1993 Authors: Amara SG; Kuhar MJ
  • Psychostimulant drugs and a dopamine hypothesis regarding addiction: update on recent research.
    Biochem Soc Symp Volume: 59 Page(s): 51 - 64
    01/01/1993 Authors: Ritz MC; Kuhar MJ
  • WITHDRAWAL OF COCAINE REDUCES THE DOPAMINE TRANSPORTER MESSENGER-RNA EXPRESSION IN 2 VENTRAL TEGMENTAL AREA SUBNUCLEI
    Volume: 61 Page(s): S69 - S69
    01/01/1993 Authors: CERRUTI C; PILOTTE N; UHL G; KUHAR MJ
  • Selective dopamine transporter inhibition by cocaine analogs.
    Neuroreport Volume: 3 Page(s): 984 - 986
    11/01/1992 Authors: Boja JW; McNeill RM; Lewin AH; Abraham P; Carroll FI; Kuhar MJ
  • Dopamine transporter imaging with novel, selective cocaine analogs.
    Neuroreport Volume: 3 Page(s): 969 - 972
    11/01/1992 Authors: Scheffel U; Dannals RF; Wong DF; Yokoi F; Carroll FI; Kuhar MJ
  • In vivo binding of [125I]RTI-55 to dopamine transporters: pharmacology and regional distribution with autoradiography.
    Synapse Volume: 12 Page(s): 37 - 46
    09/01/1992 Authors: Cline EJ; Scheffel U; Boja JW; Mitchell WM; Carroll FI; Abraham P; Lewin AH; Kuhar MJ
  • High-affinity binding of [125I]RTI-55 to dopamine and serotonin transporters in rat brain.
    Synapse Volume: 12 Page(s): 27 - 36
    09/01/1992 Authors: Boja JW; Mitchell WM; Patel A; Kopajtic TA; Carroll FI; Lewin AH; Abraham P; Kuhar MJ
  • Dopamine transport: pharmacological distinction between the synaptic membrane and the vesicular transporter in rat striatum.
    Eur J Pharmacol Volume: 218 Page(s): 175 - 177
    07/21/1992 Authors: Rostne W; Boja JW; Scherman D; Carroll FI; Kuhar MJ
  • Microheterogeneity of dopamine transporters in rat striatum and nucleus accumbens.
    Brain Res Volume: 584 Page(s): 266 - 271
    07/03/1992 Authors: Lew R; Patel A; Vaughan RA; Wilson A; Kuhar MJ
  • High potency cocaine analogs: neurochemical, imaging, and behavioral studies.
    Ann N Y Acad Sci Volume: 654 Page(s): 282 - 291
    06/28/1992 Authors: Boja JW; Cline EJ; Carroll FI; Lewin AH; Philip A; Dannals R; Wong D; Scheffel U; Kuhar MJ
  • HIGH POTENCY COCAINE ANALOGS - NEUROCHEMICAL, IMAGING, AND BEHAVIORAL-STUDIES
    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES Volume: 654 Page(s): 282 - 291
    06/28/1992 Authors: BOJA JW; CLINE EJ; CARROLL FI; LEWIN AH; PHILIP A; DANNALS R; WONG D; SCHEFFEL U; KUHAR MJ
  • Isopropyl and phenyl esters of 3 beta-(4-substituted phenyl)tropan-2 beta-carboxylic acids. Potent and selective compounds for the dopamine transporter.
    J Med Chem Volume: 35 Page(s): 2497 - 2500
    06/26/1992 Authors: Carroll FI; Abraham P; Lewin AH; Parham KA; Boja JW; Kuhar M
  • [123/125I]RTI-55, an in vivo label for the serotonin transporter.
    Synapse Volume: 11 Page(s): 134 - 139
    06/01/1992 Authors: Scheffel U; Dannals RF; Cline EJ; Ricaurte GA; Carroll FI; Abraham P; Lewin AH; Kuhar MJ
  • Probes for the cocaine receptor. Potentially irreversible ligands for the dopamine transporter.
    J Med Chem Volume: 35 Page(s): 1813 - 1817
    05/15/1992 Authors: Carroll FI; Gao Y; Abraham P; Lewin AH; Lew R; Patel A; Boja JW; Kuhar MJ
  • Stimulus generalization from cocaine to analogs with high in vitro affinity for dopamine uptake sites.
    Behav Pharmacol Volume: 3 Page(s): 113 - 116
    04/01/1992 Authors: Cline EJ; Terry P; Carroll FI; Kuhar MJ; Katz JL
  • A cocaine analog and a GBR analog label the same protein in rat striatal membranes.
    Brain Res Volume: 576 Page(s): 173 - 174
    03/27/1992 Authors: Patel A; Boja JW; Lever J; Lew R; Simantov R; Carroll FI; Lewin AH; Philip A; Gao Y; Kuhar MJ
  • Cocaine receptor: biochemical characterization and structure-activity relationships of cocaine analogues at the dopamine transporter.
    J Med Chem Volume: 35 Page(s): 969 - 981
    03/20/1992 Authors: Carroll FI; Lewin AH; Boja JW; Kuhar MJ
  • Behavioral effects of novel cocaine analogs: a comparison with in vivo receptor binding potency.
    J Pharmacol Exp Ther Volume: 260 Page(s): 1174 - 1179
    03/01/1992 Authors: Cline EJ; Scheffel U; Boja JW; Carroll FI; Katz JL; Kuhar MJ
  • Expression of a single dopamine transporter cDNA can confer two cocaine binding sites.
    Neuroreport Volume: 3 Page(s): 247 - 248
    03/01/1992 Authors: Boja JW; Markham L; Patel A; Uhl G; Kuhar MJ
  • In vivo imaging of dopamine reuptake sites in the primate brain using single photon emission computed tomography (SPECT) and iodine-123 labeled RTI-55.
    Synapse Volume: 10 Page(s): 169 - 172
    02/01/1992 Authors: Shaya EK; Scheffel U; Dannals RF; Ricaurte GA; Carroll FI; Wagner HN; Kuhar MJ; Wong DF
  • AIDS AND HIV-INFECTION IN COCAINE USERS
    Volume: 166 Page(s): 181 - 194
    01/01/1992 Authors: JARLAIS DCD; EDWARDS G; MOORE MH; ALMOND B; KLEBER HD; NEGRETE; JONES JC; WOOLVERTON WL; MUSTO DF; KALANT H
  • MOLECULAR PHARMACOLOGY OF COCAINE - A DOPAMINE HYPOTHESIS AND ITS IMPLICATIONS
    Volume: 166 Page(s): 81 - 95
    01/01/1992 Authors: KUHAR MJ
  • AIDS AND HIV-INFECTION IN COCAINE USERS
    CIBA FOUNDATION SYMPOSIA Volume: 166 Page(s): 181 - 194
    01/01/1992 Authors: JARLAIS DCD; EDWARDS G; MOORE MH; ALMOND B; KLEBER HD; NEGRETE; JONES JC; WOOLVERTON WL; MUSTO DF; KALANT H
  • N-modified analogues of cocaine: synthesis and inhibition of binding to the cocaine receptor.
    J Med Chem Volume: 35 Page(s): 141 - 144
    01/01/1992 Authors: Abraham P; Pitner JB; Lewin AH; Boja JW; Kuhar MJ; Carroll FI
  • 2 beta-substituted analogues of cocaine. Synthesis and inhibition of binding to the cocaine receptor.
    J Med Chem Volume: 35 Page(s): 135 - 140
    01/01/1992 Authors: Lewin AH; Gao YG; Abraham P; Boja JW; Kuhar MJ; Carroll FI
  • Molecular pharmacology of cocaine: a dopamine hypothesis and its implications.
    Ciba Found Symp Volume: 166 Page(s): 81 - 89
    01/01/1992 Authors: Kuhar MJ
  • Molecular mechanisms associated with cocaine effects. Possible relationships with effects of ethanol.
    Recent Dev Alcohol Volume: 10 Page(s): 273 - 302
    01/01/1992 Authors: Ritz MC; Kuhar MJ; George FR
  • A rapid binding assay for solubilized dopamine transporters using [3H]WIN 35,428.
    J Neurosci Methods Volume: 40 Page(s): 9 - 16
    11/01/1991 Authors: Vaughan RA; Simantov R; Lew R; Kuhar MJ
  • Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA.
    Science Volume: 254 Page(s): 576 - 578
    10/25/1991 Authors: Shimada S; Kitayama S; Lin CL; Patel A; Nanthakumar E; Gregor P; Kuhar M; Uhl G
  • Synthesis, ligand binding, QSAR, and CoMFA study of 3 beta-(p-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters.
    J Med Chem Volume: 34 Page(s): 2719 - 2725
    09/01/1991 Authors: Carroll FI; Gao YG; Rahman MA; Abraham P; Parham K; Lewin AH; Boja JW; Kuhar MJ
  • X-RAY AFFINITY LABELING OF DOPAMINE TRANSPORTER BY PHOTOAFFINITY LIGANDS
    Volume: 32 Page(s): 1839 - 1839
    09/01/1991 Authors: WONG FCL; BOJA JW; WONG DF; WILSON AA; CARROLL FI; KUHAR MJ; WAGNER HN
  • Neuroanatomic specificity and time course of alterations in rat brain serotonergic pathways induced by MDMA (3,4-methylenedioxymethamphetamine): assessment using quantitative autoradiography.
    Synapse Volume: 8 Page(s): 249 - 260
    08/01/1991 Authors: Battaglia G; Sharkey J; Kuhar MJ; de Souza EB
  • The dopamine hypothesis of the reinforcing properties of cocaine.
    Trends Neurosci Volume: 14 Page(s): 299 - 302
    07/01/1991 Authors: Kuhar MJ; Ritz MC; Boja JW
  • Cocaine displaces [3H]WIN 35,428 binding to dopamine uptake sites in vivo more rapidly than mazindol or GBR 12909.
    Eur J Pharmacol Volume: 198 Page(s): 203 - 205
    06/06/1991 Authors: Pgn S; Scheffel U; Kuhar MJ
  • In vivo labeling of cocaine binding sites on dopamine transporters with [3H]WIN 35,428.
    J Pharmacol Exp Ther Volume: 257 Page(s): 954 - 958
    06/01/1991 Authors: Scheffel U; Pgn S; Stathis M; Boja JW; Kuhar MJ
  • Dopamine transporters in the nucleus accumbens and the striatum have different apparent molecular weights.
    Synapse Volume: 8 Page(s): 152 - 153
    06/01/1991 Authors: Lew R; Vaughan R; Simantov R; Wilson A; Kuhar MJ
  • INVIVO LABELING OF COCAINE BINDING-SITES ON DOPAMINE TRANSPORTERS WITH [H-3] WIN-35,428
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS Volume: 257 Page(s): 954 - 958
    06/01/1991 Authors: SCHEFFEL U; POGUN S; STATHIS M; BOJA JW; KUHAR MJ
  • Synthesis and ligand binding of cocaine isomers at the cocaine receptor.
    J Med Chem Volume: 34 Page(s): 883 - 886
    03/01/1991 Authors: Carroll FI; Lewin AH; Abraham P; Parham K; Boja JW; Kuhar MJ
  • Isothiocyanate derivatives of cocaine: irreversible inhibition of ligand binding at the dopamine transporter.
    Mol Pharmacol Volume: 39 Page(s): 339 - 345
    03/01/1991 Authors: Boja JW; Rahman MA; Philip A; Lewin AH; Carroll FI; Kuhar MJ
  • [125I]RTI-55: a potent ligand for dopamine transporters.
    Eur J Pharmacol Volume: 194 Page(s): 133 - 134
    02/26/1991 Authors: Boja JW; Patel A; Carroll FI; Rahman MA; Philip A; Lewin AH; Kopajtic TA; Kuhar MJ
  • Dopamine transporter: deglycosylation with exo- and endoglycosidases.
    Brain Res Volume: 539 Page(s): 239 - 246
    01/25/1991 Authors: Lew R; Grigoriadis D; Wilson A; Boja JW; Simantov R; Kuhar MJ
  • Imaging receptors by autoradiography: computer-assisted approaches.
    J Chem Neuroanat Volume: 4 Page(s): 319 - 327
    01/01/1991 Authors: Kuhar MJ; Lloyd DG; Appel N; Loats HL
  • DOPAMINE TRANSPORTER COCAINE RECEPTOR - CHARACTERIZATION AND PURIFICATION
    Volume: 82 Page(s): 151 - 154
    01/01/1991 Authors: SIMANTOV R; VAUGHAN R; LEW R; WILSON A; KUHAR MJ
  • Emerging technologies and new directions in drug abuse research. An overview.
    Volume: 112 Page(s): 1 - 6
    01/01/1991 Authors: Snyder M
  • A GABA transporter cDNA has been cloned.
    Trends Neurosci Volume: 13 Page(s): 473 - 474
    12/01/1990 Authors: Kuhar MJ
  • [3H]WIN 35,065-2: a ligand for cocaine receptors in striatum.
    J Neurochem Volume: 55 Page(s): 1556 - 1562
    11/01/1990 Authors: Ritz MC; Boja JW; Grigoriadis D; Zaczek R; Carroll FI; Lewis AH; Kuhar MJ
  • New, potent cocaine analogs: ligand binding and transport studies in rat striatum.
    Eur J Pharmacol Volume: 184 Page(s): 329 - 332
    08/10/1990 Authors: Boja JW; Carroll FI; Rahman MA; Philip A; Lewin AH; Kuhar MJ
  • THE DOPAMINE TRANSPORTER - BINDING BY THE IRREVERSIBLE LIGANDS META-ISOTHIOCYANATOBENZOYLECGONINE AND PARA-ISOTHIOCYANATOBENZOYLECGONINE METHYL-ESTER
    Volume: 183 Page(s): 654 - 655
    07/01/1990 Authors: BOJA JW; CARROLL FI; KUHAR MJ
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    Neuropharmacology Volume: 29 Page(s): 295 - 297
    03/01/1990 Authors: Kuhar MJ; Boja JW; Cone EJ
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    NIDA Res Monogr Volume: 105 Page(s): 147 - 153
    01/01/1990 Authors: Carroll FI; Rahman MA; Philip A; Lewin AH; Boja JW; Kuhar MJ
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    Life Sci Volume: 46 Page(s): 635 - 645
    01/01/1990 Authors: Ritz MC; Cone EJ; Kuhar MJ
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    Exp Brain Res Volume: 81 Page(s): 267 - 278
    01/01/1990 Authors: Zarbin MA; Wamsley JK; Kuhar MJ
  • Dopamine transporter: biochemistry, pharmacology and imaging.
    Eur Neurol Volume: 30 Suppl 1 Page(s): 15 - 20
    01/01/1990 Authors: Kuhar MJ; Sanchez-Roa PM; Wong DF; Dannals RF; Grigoriadis DE; Lew R; Milberger M
  • [3H]cocaine binding and inhibition of [3H]dopamine uptake is similar in both the rat striatum and nucleus accumbens.
    Eur J Pharmacol Volume: 173 Page(s): 215 - 217
    12/07/1989 Authors: Boja JW; Kuhar MJ
  • Mu opiate receptors are selectively labelled by [3H]carfentanil in human and rat brain.
    Eur J Pharmacol Volume: 167 Page(s): 221 - 228
    08/22/1989 Authors: Titeler M; Lyon RA; Kuhar MJ; Frost JF; Dannals RF; Leonhardt S; Bullock A; Rydelek LT; Price DL; Struble RG
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    J Neurosci Volume: 9 Page(s): 2664 - 2670
    08/01/1989 Authors: Grigoriadis DE; Wilson AA; Lew R; Sharkey JS; Kuhar MJ
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    J Pharmacol Exp Ther Volume: 248 Page(s): 1010 - 1017
    03/01/1989 Authors: Ritz MC; Kuhar MJ
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    Synapse Volume: 3 Page(s): 372 - 375
    01/01/1989 Authors: Lew R; Grigoriadis DE; Sharkey J; Kuhar MJ
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    Synapse Volume: 4 Page(s): 390 - 392
    01/01/1989 Authors: Scheffel U; Boja JW; Kuhar MJ
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    Life Sci Volume: 45 Page(s): 2295 - 2301
    01/01/1989 Authors: Witkin JM; Goldberg SR; Katz JL; Kuhar MJ
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    Life Sci Volume: 45 Page(s): 1529 - 1535
    01/01/1989 Authors: Porrino LJ; Ritz MC; Goodman NL; Sharpe LG; Kuhar MJ; Goldberg SR
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    NIDA Res Monogr Volume: 95 Page(s): 239 - 246
    01/01/1989 Authors: Ritz MC; Boja JW; George FR; Kuhar MJ
  • [125]I-spectramide: a novel benzamide displaying potent and selective effects at the D2 dopamine receptor.
    Life Sci Volume: 45 Page(s): 1821 - 1829
    01/01/1989 Authors: Snchez-Roa PM; Grigoriadis DE; Wilson AA; Sharkey J; Dannals RF; Villemagne VL; Wong DF; Wagner HN; Kuhar MJ
  • Cocaine inhibits muscarinic cholinergic receptors in heart and brain.
    J Pharmacol Exp Ther Volume: 246 Page(s): 1048 - 1052
    09/01/1988 Authors: Sharkey J; Ritz MC; Schenden JA; Hanson RC; Kuhar MJ
  • Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity.
    J Neurosci Volume: 8 Page(s): 2788 - 2803
    08/01/1988 Authors: O'Hearn E; Battaglia G; De Souza EB; Kuhar MJ; Molliver ME
  • Cocaine binding at sigma receptors.
    Eur J Pharmacol Volume: 149 Page(s): 171 - 174
    04/27/1988 Authors: Sharkey J; Glen KA; Wolfe S; Kuhar MJ
  • Buspirone enhances benzodiazepine receptor binding in vivo.
    Neuropharmacology Volume: 27 Page(s): 275 - 280
    03/01/1988 Authors: Goeders NE; Ritz MC; Kuhar MJ
  • Cocaine self-administration appears to be mediated by dopamine uptake inhibition.
    Prog Neuropsychopharmacol Biol Psychiatry Volume: 12 Page(s): 233 - 239
    01/01/1988 Authors: Ritz MC; Lamb RJ; Goldberg SR; Kuhar MJ
  • Neuroimaging and neuropathology.
    Schizophr Bull Volume: 14 Page(s): 383 - 397
    01/01/1988 Authors: Wagner HN; Weinberger DR; Kleinman JE; Casanova MF; Gibbs CJ; Gur RE; Hornykiewicz O; Kuhar MJ; Pettegrew JW; Seeman P
  • Cocaine receptors on dopamine transporters mediate cocaine-reinforced behavior.
    NIDA Res Monogr Volume: 88 Page(s): 14 - 22
    01/01/1988 Authors: Kuhar MJ; Ritz MC; Sharkey J
  • In vivo PET and SPECT receptor imaging: new technology and tactics for receptor measurement.
    Adv Exp Med Biol Volume: 236 Page(s): 181 - 193
    01/01/1988 Authors: Wong DF; Kuhar MJ
  • Nalbuphine: an autoradiographic opioid receptor binding profile in the central nervous system of an agonist/antagonist analgesic.
    J Pharmacol Exp Ther Volume: 244 Page(s): 391 - 402
    01/01/1988 Authors: De Souza EB; Schmidt WK; Kuhar MJ
  • Cocaine receptors on dopamine transporters are related to self-administration of cocaine.
    Science Volume: 237 Page(s): 1219 - 1223
    09/04/1987 Authors: Ritz MC; Lamb RJ; Goldberg SR; Kuhar MJ
  • 3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.
    J Pharmacol Exp Ther Volume: 242 Page(s): 911 - 916
    09/01/1987 Authors: Battaglia G; Yeh SY; O'Hearn E; Molliver ME; Kuhar MJ; De Souza EB
  • Imaging receptors for drugs in neural tissue.
    Neuropharmacology Volume: 26 Page(s): 911 - 916
    07/01/1987 Authors: Kuhar MJ
  • Reductions in corticotropin releasing factor-like immunoreactivity in cerebral cortex in Alzheimer's disease, Parkinson's disease, and progressive supranuclear palsy.
    Neurology Volume: 37 Page(s): 905 - 909
    06/01/1987 Authors: Whitehouse PJ; Vale WW; Zweig RM; Singer HS; Mayeux R; Kuhar MJ; Price DL; De Souza EB
  • Beta-adrenergic receptors in human trabecular meshwork. Identification and autoradiographic localization.
    Invest Ophthalmol Vis Sci Volume: 28 Page(s): 772 - 779
    05/01/1987 Authors: Jampel HD; Lynch MG; Brown RH; Kuhar MJ; De Souza EB
  • In vivo binding of 3H-N-methylspiperone to dopamine and serotonin receptors.
    Life Sci Volume: 40 Page(s): 987 - 995
    03/09/1987 Authors: Frost JJ; Smith AC; Kuhar MJ; Dannals RF; Wagner HN
  • THE COCAINE RECEPTOR - BEHAVIORAL POTENCY CORRELATES WITH MONOAMINE UPTAKE INHIBITION
    Volume: 46 Page(s): 404 - 404
    03/01/1987 Authors: RITZ MC; KUHAR MJ
  • MDMA-INDUCED NEUROTOXICITY VISUALIZED BY INVITRO AUTORADIOGRAPHY - DIFFERENTIAL SENSITIVITY OF SEROTONERGIC NEURONS
    Volume: 46 Page(s): 404 - 404
    03/01/1987 Authors: BATTAGLIA G; KUHAR MJ; DESOUZA EB
  • Chronic cocaine administration induces opposite changes in dopamine receptors in the striatum and nucleus accumbens.
    Alcohol Drug Res Volume: 7 Page(s): 207 - 216
    01/01/1987 Authors: Goeders NE; Kuhar MJ
  • POSITRON-EMITTING TRACERS AND INVIVO BRAIN CHEMISTRY
    Volume: 32 Page(s): 768 - 768
    01/01/1987 Authors: WAGNER HN; DANNALS RF; WONG DF; FROST JJ; LINKS JM; SNYDER SH; KUHAR MJ
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    Page(s): 174 - 174
    01/01/1987 Authors: KUHAR MJ
  • Positron emission tomography reveals elevated D2 dopamine receptors in drug-naive schizophrenics.
    Science Volume: 234 Page(s): 1558 - 1563
    12/19/1986 Authors: Wong DF; Wagner HN; Tune LE; Dannals RF; Pearlson GD; Links JM; Tamminga CA; Broussolle EP; Ravert HT; Wilson AA
  • Benzodiazepine receptor GABA ratios: regional differences in rat brain and modulation by adrenalectomy.
    Eur J Pharmacol Volume: 129 Page(s): 363 - 366
    10/07/1986 Authors: Goeders NE; De Souza EB; Kuhar MJ
  • 3H-3-N-methylspiperone labels D2 dopamine receptors in basal ganglia and S2 serotonin receptors in cerebral cortex.
    J Neurosci Volume: 6 Page(s): 2941 - 2949
    10/01/1986 Authors: Lyon RA; Titeler M; Frost JJ; Whitehouse PJ; Wong DF; Wagner HN; Dannals RF; Links JM; Kuhar MJ
  • Benzodiazepine receptors in rat brain are altered by adrenalectomy.
    Brain Res Volume: 381 Page(s): 176 - 181
    08/27/1986 Authors: De Souza EB; Goeders NE; Kuhar MJ
  • REDUCTIONS IN CORTICOTROPIN-RELEASING FACTOR-LIKE IMMUNOREACTIVITY IN CEREBRAL-CORTEX IN ALZHEIMERS-DISEASE, PARKINSONS-DISEASE, AND PROGRESSIVE SUPRANUCLEAR PALSY
    Volume: 20 Page(s): 125 - 126
    07/01/1986 Authors: WHITEHOUSE PJ; ZWEIG RM; KUHAR MJ; PRICE DL; VALET WW; DESOUZA EB
  • Response: human brain receptor distribution.
    Science Volume: 232 Page(s): 1270 - 1271
    06/06/1986 Authors: Wong DF; Wagner HN; Dannals RF; Links JM; Kuhar MJ; Gjedde A
  • Human brain receptor distribution.
    Science Volume: 232 Page(s): 1269 - 1271
    06/06/1986 Authors: Frey KA; Agranoff BW; Young AB; Hichwa RD; Ehrenkaufer RL
  • Autoradiographic localization of high affinity GABA, benzodiazepine, dopaminergic, adrenergic and muscarinic cholinergic receptors in the rat, monkey and human retina.
    Brain Res Volume: 374 Page(s): 75 - 92
    05/21/1986 Authors: Zarbin MA; Wamsley JK; Palacios JM; Kuhar MJ
  • ALZHEIMERS-DISEASE - RECIPROCAL CHANGES IN CORTICOTROPIN-RELEASING FACTOR (CRF)-LIKE IMMUNOREACTIVITY AND CRF RECEPTORS IN CEREBRAL-CORTEX
    Volume: 36 Page(s): 271 - 271
    04/01/1986 Authors: DESOUZA EB; WHITEHOUSE PJ; PRICE DL; VALE WW; KUHAR MJ
  • Quantification of Neuroreceptors in the living human brain. II. Inhibition studies of receptor density and affinity.
    J Cereb Blood Flow Metab Volume: 6 Page(s): 147 - 153
    04/01/1986 Authors: Wong DF; Gjedde A; Wagner HN; Dannals RF; Douglass KH; Links JM; Kuhar MJ
  • REDUCTIONS IN NEUROTRANSMITTER RECEPTORS IN THE NUCLEUS BASALIS OF MEYNERT IN ALZHEIMERS-DISEASE
    Volume: 36 Page(s): 273 - 273
    04/01/1986 Authors: WHITEHOUSE PJ; MARCUS K; PRICE DL; KUHAR MJ; WAGSTER WV
  • REDUCTIONS OF SEROTONIN RECEPTORS IN ALZHEIMERS-DISEASE - AN AUTORADIOGRAPHIC STUDY
    Volume: 36 Page(s): 270 - 270
    04/01/1986 Authors: GONZALEZ J; WHITEHOUSE PJ; ZWEIG RM; YAGALOFF KA; HARTIG PR; MARCUS K; KUHAR MJ; PRICE DL; STEELE CS; FOLSTEIN MF
  • Reciprocal changes in corticotropin-releasing factor (CRF)-like immunoreactivity and CRF receptors in cerebral cortex of Alzheimer's disease.
    Nature Volume: 319 Page(s): 593 - 595
    02/13/1986 Authors: De Souza EB; Whitehouse PJ; Kuhar MJ; Price DL; Vale WW
  • Neurotransmitter receptor mapping by autoradiography and other methods.
    Annu Rev Neurosci Volume: 9 Page(s): 27 - 59
    01/01/1986 Authors: Kuhar MJ; De Souza EB; Unnerstall JR
  • Corticotropin-releasing factor receptors in the pituitary gland and central nervous system: methods and overview.
    Methods Enzymol Volume: 124 Page(s): 560 - 590
    01/01/1986 Authors: De Souza EB; Kuhar MJ
  • Corticotropin-releasing factor receptors: autoradiographic identification.
    Res Publ Assoc Res Nerv Ment Dis Volume: 64 Page(s): 179 - 198
    01/01/1986 Authors: De Souza EB; Kuhar MJ
  • IMAGING DOPAMINE-RECEPTORS IN THE HUMAN-BRAIN
    Volume: 31 Page(s): 3 - 3
    01/01/1986 Authors: WAGNER HN; WONG DF; DANNALS RF; KUHAR MJ; LINKS JM; FROST JJ; FOLSTEIN M; FOLSTEIN S
  • OPIATE RECEPTOR IMAGING IN THE LIVING HUMAN-BRAIN
    Volume: 31 Page(s): 225 - 225
    01/01/1986 Authors: WAGNER HN; FROST JJ; DANNALS RF; LINKS JM; BICE AN; KUHAR MJ; SNYDER SH
  • Corticotropin-releasing factor receptors are widely distributed within the rat central nervous system: an autoradiographic study.
    J Neurosci Volume: 5 Page(s): 3189 - 3203
    12/01/1985 Authors: De Souza EB; Insel TR; Perrin MH; Rivier J; Vale WW; Kuhar MJ
  • Axonal transport of alpha-bungarotoxin binding sites in rat sciatic nerve.
    Brain Res Volume: 340 Page(s): 269 - 276
    08/12/1985 Authors: Millington WR; Aizenman E; Bierkamper GG; Zarbin MA; Kuhar MJ
  • Neurotransmitter receptor alterations in Huntington's disease: autoradiographic and homogenate studies with special reference to benzodiazepine receptor complexes.
    Ann Neurol Volume: 18 Page(s): 202 - 210
    08/01/1985 Authors: Whitehouse PJ; Trifiletti RR; Jones BE; Folstein S; Price DL; Snyder SH; Kuhar MJ
  • Benzodiazepine receptor binding in vivo with [3H]-Ro 15-1788.
    Life Sci Volume: 37 Page(s): 345 - 355
    07/29/1985 Authors: Goeders NE; Kuhar MJ
  • Benzodiazepine receptor binding with a new ligand, Ro 22-8515.
    Eur J Pharmacol Volume: 113 Page(s): 147 - 148
    07/11/1985 Authors: Goeders NE; Horst WD; O'Brien R; Bautz G; Kuhar MJ
  • [3H]Nitrendipine binding to calcium channels in bovine and rat pituitary.
    J Neurochem Volume: 44 Page(s): 1955 - 1958
    06/01/1985 Authors: Titeler M; De Souza EB; Kuhar MJ
  • Vasoactive intestinal peptide receptor localization in rat forebrain by autoradiography.
    Neurosci Lett Volume: 56 Page(s): 113 - 120
    05/14/1985 Authors: De Souza EB; Seifert H; Kuhar MJ
  • Differential regulation of corticotropin-releasing factor receptors in anterior and intermediate lobes of pituitary and in brain following adrenalectomy in rats.
    Neurosci Lett Volume: 56 Page(s): 121 - 128
    05/01/1985 Authors: De Souza EB; Insel TR; Perrin MH; Rivier J; Vale WW; Kuhar MJ
  • Neurotransmitter receptors in amyotrophic lateral sclerosis: possible relationship to sparing of eye movements.
    Ann Neurol Volume: 17 Page(s): 518
    05/01/1985 Authors: Whitehouse PJ; Wamsley JK; Zarbin MA; Price DL; Kuhar MJ
  • Corticotropin-releasing factor receptors in human pituitary gland: autoradiographic localization.
    Neuroendocrinology Volume: 40 Page(s): 419 - 422
    05/01/1985 Authors: De Souza EB; Perrin MH; Whitehouse PJ; Rivier J; Vale W; Kuhar MJ
  • Depletion of peripheral-type benzodiazepine receptors after hypophysectomy in rat adrenal gland and testis.
    Eur J Pharmacol Volume: 110 Page(s): 41 - 46
    03/09/1985 Authors: Anholt RR; De Souza EB; Kuhar MJ; Snyder SH
  • Autoradiographic localization of (125I-Tyr4)bombesin-binding sites in rat brain.
    J Neurosci Volume: 5 Page(s): 429 - 437
    02/01/1985 Authors: Zarbin MA; Kuhar MJ; O'Donohue TL; Wolf SS; Moody TW
  • Imaging neuroreceptors in the human brain in health and disease.
    Radioisotopes Volume: 34 Page(s): 103 - 107
    02/01/1985 Authors: Wagner HN; Dannals RF; Frost JJ; Wong DF; Ravert HT; Wilson AA; Links JM; Burns HD; Kuhar MJ; Snyder SH
  • Localization of beta adrenoceptor subtypes in rat kidney by light microscopic autoradiography.
    J Pharmacol Exp Ther Volume: 232 Page(s): 561 - 569
    02/01/1985 Authors: Summers RJ; Stephenson JA; Kuhar MJ
  • Peripheral-type benzodiazepine receptors in endocrine organs: autoradiographic localization in rat pituitary, adrenal, and testis.
    Endocrinology Volume: 116 Page(s): 567 - 573
    02/01/1985 Authors: De Souza EB; Anholt RR; Murphy KM; Snyder SH; Kuhar MJ
  • INVIVO ASSESSMENT OF DOPAMINE D-2 AND SEROTONIN S-2 RECEPTORS MEASURED BY C-11 N-METHYLSPIPERONE (NMSP) IN MANIC-DEPRESSIVE ILLNESS
    JOURNAL OF NUCLEAR MEDICINE Volume: 26 Page(s): P107 - P107
    01/01/1985 Authors: WONG DF; PEARLSON G; WAGNER HN; DANNALS RF; SUNEJA S; BJORGVINSSON E; LINKS JM; RAVERT HT; WILSON AA; SCHAERF F
  • INVIVO ASSESSMENT OF DOPAMINE AND SEROTONIN RECEPTORS MEASURED BY C-11 N-METHYLSPIPERONE (NMSP) IN PATIENTS WITH SCHIZOPHRENIA
    JOURNAL OF NUCLEAR MEDICINE Volume: 26 Page(s): P107 - P107
    01/01/1985 Authors: WONG DF; TUNE LE; WAGNER HN; SUNEJA S; BJORVINSSON E; PEARLSON G; DANNALS RF; RAVERT HT; WILSON AA; LINKS JM
  • Dopamine receptor binding of C-11-3-N-methylspiperone in the caudate in schizophrenia and bipolar disorder: a preliminary report.
    Psychopharmacol Bull Volume: 21 Page(s): 595 - 598
    01/01/1985 Authors: Wong DF; Wagner HN; Pearlson G; Dannals RF; Links JM; Ravert HT; Wilson AA; Suneja S; Bjorvvinssen E; Kuhar MJ
  • DOPAMINE AND SEROTONIN RECEPTORS MEASURED INVIVO IN HUNTINGTONS-DISEASE WITH C-11 N-METHYLSPIPERONE PET IMAGING
    JOURNAL OF NUCLEAR MEDICINE Volume: 26 Page(s): P107 - P107
    01/01/1985 Authors: WONG DF; LINKS JM; WAGNER HN; FOLSTEIN SE; SUNEJA S; DANNALS RF; RAVERT HT; WILSON AA; TUNE LE; PEARLSON G
  • Atlas of dopamine receptor images (PET) of the human brain.
    J Comput Assist Tomogr Volume: 9 Page(s): 129 - 140
    01/01/1985 Authors: Inoue Y; Wagner HN; Wong DF; Links JM; Frost JJ; Dannals RF; Rosenbaum AE; Takeda K; Di Chiro G; Kuhar MJ
  • Receptor mapping in neuropharmacology by autoradiography: some technical problems.
    NIDA Res Monogr Volume: 62 Page(s): 1 - 12
    01/01/1985 Authors: Kuhar MJ; Unnerstall JR; De Souza EB
  • ASSESSMENT OF DOPAMINE RECEPTOR BLOCKADE BY NEUROLEPTIC DRUGS IN THE LIVING HUMAN-BRAIN
    JOURNAL OF NUCLEAR MEDICINE Volume: 26 Page(s): P52 - P53
    01/01/1985 Authors: WONG DF; WAGNER HN; COYLE J; SNYDER S; DANNALS R; LAFRANCE N; BICE A; PEARLSON G; LINKS J; PAULOS M
  • Imaging opiate receptors in the human brain by positron tomography.
    J Comput Assist Tomogr Volume: 9 Page(s): 231 - 236
    01/01/1985 Authors: Frost JJ; Wagner HN; Dannals RF; Ravert HT; Links JM; Wilson AA; Burns HD; Wong DF; McPherson RW; Rosenbaum AE
  • FURTHER DEVELOPMENT AND VALIDATION OF THE MODEL FOR INVIVO QUANTIFICATION OF HUMAN DOPAMINE-RECEPTORS
    Volume: 26 Page(s): P52 - P52
    01/01/1985 Authors: WONG DF; GJEDDE A; WAGNER HN; DOUGLASS KH; DANNALS RF; SNYDER SH; KUHAR MJ
  • Effects of age on dopamine and serotonin receptors measured by positron tomography in the living human brain.
    Science Volume: 226 Page(s): 1393 - 1396
    12/21/1984 Authors: Wong DF; Wagner HN; Dannals RF; Links JM; Frost JJ; Ravert HT; Wilson AA; Rosenbaum AE; Gjedde A; Douglass KH
  • (3-N-[11C]methyl)spiperone, a ligand binding to dopamine receptors: radiochemical synthesis and biodistribution studies in mice.
    J Nucl Med Volume: 25 Page(s): 1222 - 1227
    11/01/1984 Authors: Burns HD; Dannals RF; Langstrm B; Ravert HT; Zemyan SE; Duelfer T; Wong DF; Frost JJ; Kuhar MJ; Wagner HN
  • Autoradiographic localization of 5-HT1 receptors to human and canine basilar arteries.
    Brain Res Volume: 310 Page(s): 193 - 196
    09/17/1984 Authors: Peroutka SJ; Kuhar MJ
  • Parkinson's disease: depletion of substantia nigra neurotensin receptors.
    Brain Res Volume: 308 Page(s): 186 - 190
    08/06/1984 Authors: Uhl GR; Whitehouse PJ; Price DL; Tourtelotte WW; Kuhar MJ
  • Effects of postmortem delay and temperature on neurotransmitter receptor binding in a rat model of the human autopsy process.
    J Neurochem Volume: 43 Page(s): 553 - 559
    08/01/1984 Authors: Whitehouse PJ; Lynch D; Kuhar MJ
  • Characterization and localization of the muscarinic cholinergic receptor in human prostatic tissue.
    J Urol Volume: 132 Page(s): 397 - 402
    08/01/1984 Authors: Lepor H; Kuhar MJ
  • Characterization of muscarinic cholinergic receptor binding in the vas deferens, bladder, prostate and penis of the rabbit.
    J Urol Volume: 132 Page(s): 392 - 396
    08/01/1984 Authors: Lepor H; Kuhar MJ
  • Dopamine receptors in the anterior lobe of the human pituitary gland: autoradiographic localization.
    Brain Res Volume: 306 Page(s): 391 - 395
    07/23/1984 Authors: De Souza EB; Kuhar MJ
  • Corticotropin-releasing factor receptors in rat forebrain: autoradiographic identification.
    Science Volume: 224 Page(s): 1449 - 1451
    06/29/1984 Authors: De Souza EB; Perrin MH; Insel TR; Rivier J; Vale WW; Kuhar MJ
  • Chronic neuroleptic treatment enhances neurotensin receptor binding in human and rat substantia nigra.
    Nature Volume: 309 Page(s): 350 - 352
    05/24/1984 Authors: Uhl GR; Kuhar MJ
  • Corticotropin-releasing factor receptors in rat pituitary gland: autoradiographic localization.
    Brain Res Volume: 296 Page(s): 202 - 207
    03/26/1984 Authors: De Souza EB; Perrin MH; Rivier J; Vale WW; Kuhar MJ
  • Distribution of muscarinic cholinergic high and low affinity agonist binding sites: a light microscopic autoradiographic study.
    Brain Res Bull Volume: 12 Page(s): 233 - 243
    03/01/1984 Authors: Wamsley JK; Zarbin MA; Kuhar MJ
  • Distribution of alpha 2 agonist binding sites in the rat and human central nervous system: analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents.
    Brain Res Volume: 319 Page(s): 69 - 101
    03/01/1984 Authors: Unnerstall JR; Kopajtic TA; Kuhar MJ
  • THE EFFECTS OF AGE ON DOPAMINE-RECEPTORS MEASURED BY POSITRON TOMOGRAPHY IN THE LIVING HUMAN-BRAIN
    Volume: 25 Page(s): P73 - P73
    01/01/1984 Authors: WONG DF; WAGNER HN; DANNALS RF; FROST JJ; RAVERT HV; LINKS JM; FOLSTEIN MF; JENSEN BA; KUHAR MJ; TOUNG JT
  • EFFECTS OF AGE AND SEX ON DOPAMINE-RECEPTORS IN THE LIVING HUMAN-BRAIN
    Volume: 16 Page(s): 128 - 128
    01/01/1984 Authors: WONG DF; WAGNER HN; DANNALS RF; FROST JJ; RAVERT HT; LINKS JM; FOLSTEIN MF; JENSEN BA; KUHAR MJ; TOUNG JT
  • Anatomic localization of cholecystokinin receptors to the pyloric sphincter.
    Am J Physiol Volume: 246 Page(s): R127 - R130
    01/01/1984 Authors: Smith GT; Moran TH; Coyle JT; Kuhar MJ; O'Donahue TL; McHugh PR
  • Mapping receptors for alpha 2-agonists in the central nervous system.
    J Cardiovasc Pharmacol Volume: 6 Suppl 3 Page(s): S536 - S542
    01/01/1984 Authors: Kuhar MJ; Unnerstall JR
  • CORTICOTROPIN-RELEASING FACTOR RECEPTORS IN BRAIN - AUTORADIOGRAPHIC IDENTIFICATION
    Volume: 41 Page(s): 1223 - 1223
    01/01/1984 Authors: DESOUZA EB; INSEL TR; KUHAR MJ
  • RECEPTORS IN THE NUCLEUS BASALIS OF PRIMATES - AN INVITRO AUTORADIOGRAPHIC STUDY
    Volume: 16 Page(s): 118 - 118
    01/01/1984 Authors: WHITEHOUSE PJ; JONES BE; KOPAJTIC TA; PRICE DL; KUHAR MJ
  • Assessment of dopamine receptor densities in the human brain with carbon-11-labeled N-methylspiperone.
    Ann Neurol Volume: 15 Suppl Page(s): S79 - S84
    01/01/1984 Authors: Wagner HN; Burns HD; Dannals RF; Wong DF; Langstrm B; Duelfer T; Frost JJ; Ravert HT; Links JM; Rosenbloom SB
  • AXONAL-TRANSPORT OF MUSCARINIC CHOLINERGIC RECEPTORS AND ITS IMPLICATIONS
    TRENDS IN PHARMACOLOGICAL SCIENCES Page(s): 53 - 54
    01/01/1984 Authors: KUHAR MJ; ZARBIN MA
  • CANINE INHERITED ATAXIA - NEUROTRANSMITTER RECEPTORS IN THE CEREBELLUM
    Volume: 16 Page(s): 135 - 135
    01/01/1984 Authors: TRONCOSO JC; CORK LC; WHITEHOUSE PJ; KUHAR MJ; PRICE DL
  • IMAGING OPIATE RECEPTORS WITH POSITRON EMISSION TOMOGRAPHY
    Volume: 25 Page(s): P73 - P73
    01/01/1984 Authors: FROST JJ; DANNALS RF; RAVERT HT; WILSON AA; WONG DF; LINKS JM; BURNS HD; KUHAR MJ; SNYDER SH; WAGNER HN
  • Normalization of spiroperidol binding in the denervated rat striatum by homologous grafts of substantia nigra.
    Science Volume: 222 Page(s): 937 - 939
    11/25/1983 Authors: Freed WJ; Ko GN; Niehoff DL; Kuhar MJ; Hoffer BJ; Olson L; Cannon-Spoor HE; Morihisa JM; Wyatt RJ
  • Differential localization of type I and type II benzodiazepine binding sites in substantia nigra.
    Nature Volume: 306 Page(s): 57 - 60
    11/03/1983 Authors: Lo MM; Niehoff DL; Kuhar MJ; Snyder SH
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    J Neurosci Volume: 3 Page(s): 2091 - 2097
    10/01/1983 Authors: Niehoff DL; Kuhar MJ
  • Imaging dopamine receptors in the human brain by positron tomography.
    Science Volume: 221 Page(s): 1264 - 1266
    09/23/1983 Authors: Wagner HN; Burns HD; Dannals RF; Wong DF; Langstrom B; Duelfer T; Frost JJ; Ravert HT; Links JM; Rosenbloom SB
  • Axonal transport of beta-adrenergic receptors. Antero- and retrogradely transported receptors differ in agonist affinity and nucleotide sensitivity.
    Mol Pharmacol Volume: 24 Page(s): 341 - 348
    09/01/1983 Authors: Zarbin MA; Palacios JM; Wamsley JK; Kuhar MJ
  • Autoradiographic differentiation of multiple benzodiazepine receptors by detergent solubilization and pharmacologic specificity.
    Neurosci Lett Volume: 39 Page(s): 37 - 44
    08/19/1983 Authors: Lo MM; Niehoff DL; Kuhar MJ; Snyder SH
  • Benzodiazepine receptors: preferential stimulation of Type 1 receptors by pentobarbital.
    Eur J Pharmacol Volume: 92 Page(s): 131 - 134
    08/19/1983 Authors: Niehoff DL; Mashal RD; Kuhar MJ
  • Autoradiographic localization of beta-adrenoceptors in rat kidney.
    Eur J Pharmacol Volume: 91 Page(s): 305 - 310
    07/22/1983 Authors: Summers RJ; Kuhar MJ
  • Amyotrophic lateral sclerosis: alterations in neurotransmitter receptors.
    Ann Neurol Volume: 14 Page(s): 8 - 16
    07/01/1983 Authors: Whitehouse PJ; Wamsley JK; Zarbin MA; Price DL; Tourtellotte WW; Kuhar MJ
  • Adenosine receptors: autoradiographic evidence for their location on axon terminals of excitatory neurons.
    Science Volume: 220 Page(s): 967 - 969
    05/27/1983 Authors: Goodman RR; Kuhar MJ; Hester L; Snyder SH
  • Autoradiographic localization of cholecystokinin receptors in rodent brain.
    J Neurosci Volume: 3 Page(s): 877 - 906
    04/01/1983 Authors: Zarbin MA; Innis RB; Wamsley JK; Snyder SH; Kuhar MJ
  • Ontogeny of opiate binding sites in the hippocampus, olfactory bulb and other regions of the rat forebrain by autoradiographic methods.
    Brain Res Volume: 283 Page(s): 157 - 169
    04/01/1983 Authors: Unnerstall JR; Molliver ME; Kuhar MJ; Palacios JM
  • Autoradiographic visualization of rat brain binding sites for bombesin-like peptides.
    Eur J Pharmacol Volume: 87 Page(s): 163 - 164
    01/28/1983 Authors: Wolf SS; Moody TW; O'Donohue TL; Zarbin MA; Kuhar MJ
  • CHANGES OF MOTOR NEURON CHOLINERGIC RECEPTORS AFTER AXOTOMY
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 42 Page(s): 313 - 313
    01/01/1983 Authors: TRONCOSO JC; WHITEHOUSE PJ; KUHAR MJ; GRIFFIN JW; CORK LC; PRICE DL
  • I-125-ALPHA-BUNGAROTOXIN BINDING-SITES UNDERGO AXONAL-TRANSPORT IN RAT SCIATIC-NERVE
    Volume: 42 Page(s): 1147 - 1147
    01/01/1983 Authors: AIZENMAN E; MILLINGTON WR; ZARBIN MA; BIERKAMPER GG; KUHAR MJ
  • Distribution and physiological significance of opioid receptors in the brain.
    Br Med Bull Volume: 39 Page(s): 47 - 52
    01/01/1983 Authors: Atweh SF; Kuhar MJ
  • In vitro labeling receptor autoradiography: loss of label during ethanol dehydration and preparative procedures.
    Brain Res Volume: 244 Page(s): 178 - 181
    07/22/1982 Authors: Kuhar MJ; Unnerstall JR
  • Quantitative receptor autoradiography using [3H]ultrofilm: application to multiple benzodiazepine receptors.
    J Neurosci Methods Volume: 6 Page(s): 59 - 73
    07/01/1982 Authors: Unnerstall JR; Niehoff DL; Kuhar MJ; Palacios JM
  • Axonal transport of muscarinic cholinergic receptors in rat vagus nerve: high and low affinity agonist receptors move in opposite directions and differ in nucleotide sensitivity.
    J Neurosci Volume: 2 Page(s): 934 - 941
    07/01/1982 Authors: Zarbin MA; Wamsley JK; Kuhar MJ
  • Effects of gamma-aminobutyric acid agonist and antagonist drugs on local cerebral glucose utilization.
    J Neurosci Volume: 2 Page(s): 853 - 860
    07/01/1982 Authors: Palacios JM; Kuhar MJ; Rapoport SI; London ED
  • Binding of a radiolabeled triazolopyridazine to a subtype of benzodiazepine receptor in the rat cerebellum.
    J Pharmacol Exp Ther Volume: 221 Page(s): 670 - 675
    06/01/1982 Authors: Niehoff DL; Mashal RD; Horst WD; O'Brien RA; Palacios JM; Kuhar MJ
  • Receptors for clonidine in brain: insights into therapeutic actions.
    J Clin Psychiatry Volume: 43 Page(s): 17 - 19
    06/01/1982 Authors: Kuhar MJ
  • Distribution of opiate receptors in the monkey brain: an autoradiographic study.
    Neuroscience Volume: 7 Page(s): 595 - 613
    03/01/1982 Authors: Wamsley JK; Zarbin MA; Young WS; Kuhar MJ
  • Peptide receptors undergo axonal transport in the rat vagus nerve.
    Adv Biochem Psychopharmacol Volume: 33 Page(s): 463 - 470
    01/01/1982 Authors: Zarbin MA; Wamsley JK; Kuhar MJ
  • Beta adrenergic receptor localization in rat brain by light microscopic autoradiography.
    Neurochem Int Volume: 4 Page(s): 473 - 490
    01/01/1982 Authors: Palacios J; Kuhar MJ
  • LOSS OF DRUG AND NEUROTRANSMITTER RECEPTORS IN THE SPINAL-CORD OF PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS
    Volume: 32 Page(s): A216 - A216
    01/01/1982 Authors: WHITEHOUSE PJ; WAMSLEY JK; ZARBIN MA; PRICE DL; KUHAR MJ; DAVIS L; TOURTELLOTTE W
  • COMPUTER IMAGE-ANALYSIS IN NEURODEGENERATIVE DISORDERS
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 41 Page(s): 360 - 360
    01/01/1982 Authors: WHITEHOUSE PJ; PRICE DL; HEDREEN JC; STRUBLE RG; CRISS TB; STERNER RE; KUHAR MJ
  • CORRELATION OF INVITRO AND INVIVO BINDING OF SPIPERONE ANALOGS IN THE BRAIN
    Volume: 23 Page(s): P22 - P22
    01/01/1982 Authors: SCHEININ B; POGUN S; SCHEFFEL U; WAUD JM; DUELFER T; DANNALS RF; BURNS HD; CORLEY EG; KUHAR MJ; WAGNER HN
  • Neurotensin receptors are located on dopamine-containing neurones in rat midbrain.
    Nature Volume: 294 Page(s): 587 - 589
    12/10/1981 Authors: Palacios JM; Kuhar MJ
  • Autoradiographic localization of opioid receptors in the mammalian retina.
    Neurosci Lett Volume: 27 Page(s): 19 - 24
    11/18/1981 Authors: Wamsley JK; Palacios JM; Kuhar MJ
  • Ontogeny of high-affinity GABA and benzodiazepine receptors in the rat cerebellum: an autoradiographic study.
    Brain Res Volume: 254 Page(s): 531 - 539
    11/01/1981 Authors: Palacios JM; Kuhar MJ
  • High affinity GABA receptors-autoradiographic localization.
    Brain Res Volume: 222 Page(s): 285 - 307
    10/19/1981 Authors: Palacios JM; Wamsley JK; Kuhar MJ
  • Receptor autoradiography with tritium-sensitive film: potential for computerized densitometry.
    Neurosci Lett Volume: 25 Page(s): 101 - 105
    09/01/1981 Authors: Palacios JM; Niehoff DL; Kuhar MJ
  • Benzodiazepine receptors are coupled to a subpopulation of gamma-aminobutyric acid (GABA) receptors: evidence from a quantitative autoradiographic study.
    J Pharmacol Exp Ther Volume: 218 Page(s): 797 - 804
    09/01/1981 Authors: Unnerstall JR; Kuhar MJ; Niehoff DL; Palacios JM
  • Cholecystokinin receptors: presence and axonal flow in the rat vagus nerve.
    Life Sci Volume: 29 Page(s): 697 - 705
    08/17/1981 Authors: Zarbin MA; Wamsley JK; Innis RB; Kuhar MJ
  • Muscarinic cholinergic receptors flow in the sciatic nerve.
    Brain Res Volume: 217 Page(s): 155 - 161
    07/27/1981 Authors: Wamsley JK; Zarbin MA; Kuhar MJ
  • Muscarinic cholinergic receptor localization in brain by electron microscopic autoradiography.
    Brain Res Volume: 216 Page(s): 1 - 9
    07/06/1981 Authors: Kuhar MJ; Taylor N; Wamsley JK; Hulme EC; Birdsall NJ
  • GABA benzodiazepine and histamine-H1 receptors in the guinea pig cerebellum: effects of kainic acid injections studied by autoradiographic methods.
    Brain Res Volume: 214 Page(s): 155 - 162
    06/09/1981 Authors: Palacios JM; Wamsley JK; Kuhar MJ
  • [3H]Spiperone binding sites in brain: autoradiographic localization of multiple receptors.
    Brain Res Volume: 213 Page(s): 277 - 289
    06/01/1981 Authors: Palacios JM; Niehoff DL; Kuhar MJ
  • Increases and decreases in local cerebral glucose utilization in response to GABA agonists.
    Eur J Pharmacol Volume: 71 Page(s): 333 - 336
    05/08/1981 Authors: Palacios JM; Kuhar MJ; Rapoport SI; London ED
  • Autoradiographic localization of CCK receptors in guinea pig brain.
    Eur J Pharmacol Volume: 71 Page(s): 349 - 350
    05/08/1981 Authors: Zarbin MA; Innis RB; Wamsley JK; Snyder SH; Kuhar MJ
  • Glycine receptor: light microscopic autoradiographic localization with [3H]strychnine.
    J Neurosci Volume: 1 Page(s): 532 - 547
    05/01/1981 Authors: Zarbin MA; Wamsley JK; Kuhar MJ
  • Neurotensin receptor localization by light microscopic autoradiography in rat brain.
    Brain Res Volume: 206 Page(s): 273 - 285
    02/16/1981 Authors: Young WS; Kuhar MJ
  • Autoradiographic localization of muscarinic cholinergic receptors in rat brainstem.
    J Neurosci Volume: 1 Page(s): 176 - 191
    02/01/1981 Authors: Wamsley JK; Lewis MS; Young WS; Kuhar MJ
  • Multiple benzodiazepine receptor localization by light microscopic radiohistochemistry.
    J Pharmacol Exp Ther Volume: 216 Page(s): 425 - 430
    02/01/1981 Authors: Young WS; Niehoff D; Kuhar MJ; Beer B; Lippa AS
  • SYNTHESIS OF RADIOTRACERS FOR INVIVO MAPPING AND QUANTIFICATION OF DOPAMINE-RECEPTORS
    Volume: 22 Page(s): P12 - P13
    01/01/1981 Authors: CORLEY EG; BURNS HD; FROST JJ; DUELFER T; KUHAR MJ; WAGNER HN
  • RECEPTOR AUTORADIOGRAPHY WITH TRITIUM-SENSITIVE FILM - ANALYSIS BY COMPUTERIZED DENSITOMETRY
    Volume: 29 Page(s): 894 - 894
    01/01/1981 Authors: PALACIOS JM; KUHAR MJ
  • Autoradiographic Determination of Neurotransmitter Receptor Distributions in the Cerebral and Cerebellar Cortices 1 , 2.
    J Histochem Cytochem Volume: 29 Page(s): 125 - 135
    01/01/1981 Authors: Wamsley JK; Palacios JM; Young WS; Kuhar MJ
  • Anatomical mapping of clonidine (alpha-2 noradrenergic) receptors in rat brain: relationship to function.
    Prog Clin Biol Res Volume: 71 Page(s): 41 - 52
    01/01/1981 Authors: Young WS; Kuhar MJ
  • Autoradiographic determination of neurotransmitter receptor distributions in the cerebral and cerebellar cortices.
    J Histochem Cytochem Volume: 29 Page(s): 125 - 135
    01/01/1981 Authors: Wamsley JK; Palacios JM; Young WS; Kuhar MJ
  • GABA and glycine receptors in rat brain: autoradiographic localization.
    Adv Biochem Psychopharmacol Volume: 29 Page(s): 445 - 451
    01/01/1981 Authors: Palacios JM; Wamsley JK; Zarbin MA; Kuhar MJ
  • Radiohistochemical studies of benzodiazepine and GABA receptors and their interactions.
    Adv Biochem Psychopharmacol Volume: 26 Page(s): 53 - 60
    01/01/1981 Authors: Palacios JM; Unnerstall JR; Young WS; Kuhar MJ
  • The distribution of histamine H1-receptors in the rat brain: an autoradiographic study.
    Neuroscience Volume: 6 Page(s): 15 - 37
    01/01/1981 Authors: Palacios JM; Wamsley JK; Kuhar MJ
  • INVITRO BINDING-STUDIES OF NEW BUTYROPHENONE ANALOGS DESIGNED TO INTERACT WITH DOPAMINE-RECEPTORS
    Volume: 22 Page(s): P73 - P74
    01/01/1981 Authors: POGUN S; WAUD J; BURNS HD; CORLEY EG; DUELFER T; DRANBAUER B; KUHAR M; WAGNER HN
  • alpha 2-Adrenergic receptors are associated with renal proximal tubules.
    Eur J Pharmacol Volume: 67 Page(s): 493 - 495
    10/31/1980 Authors: Young WS; Kuhar MJ
  • Muscarinic cholinergic receptors: autoradiographic localization of high and low affinity agonist binding sites.
    Brain Res Volume: 200 Page(s): 1 - 12
    10/27/1980 Authors: Wamsley JK; Zarbin MA; Birdsall NJ; Kuhar MJ
  • Opioid receptors undergo axonal flow.
    Science Volume: 210 Page(s): 76 - 78
    10/03/1980 Authors: Young WS; Wamsley JK; Zarbin MA; Kuhar MJ
  • Differentiation of delta and mu opiate receptor localizations by light microscopic autoradiography.
    Proc Natl Acad Sci U S A Volume: 77 Page(s): 6239 - 6243
    10/01/1980 Authors: Goodman RR; Snyder SH; Kuhar MJ; Young WS
  • Striatal opiate receptors: pre- and postsynaptic localization.
    Life Sci Volume: 27 Page(s): 1175 - 1183
    09/29/1980 Authors: Murrin LC; Coyle JT; Kuhar MJ
  • Inhibition of high affinity choline uptake. Structure activity studies.
    Biochem Pharmacol Volume: 29 Page(s): 2413 - 2416
    09/15/1980 Authors: Batzold F; DeHaven R; Kuhar MJ; Birdsall N
  • Beta-adrenergic-receptor localization by light microscopic autoradiography.
    Science Volume: 208 Page(s): 1378 - 1380
    06/20/1980 Authors: Palacios JM; Kuhar MJ
  • Immunohistochemical localization of enkephalin in rat forebrain.
    Brain Res Volume: 190 Page(s): 153 - 174
    05/19/1980 Authors: Wamsley JK; Young WS; Kuhar MJ
  • Serotonin receptor localization in rat brain by light microscopic autoradiography.
    Eur J Pharmacol Volume: 62 Page(s): 237 - 239
    03/21/1980 Authors: Young WS; Kuhar MJ
  • Noradrenergic alpha 1 and alpha 2 receptors: light microscopic autoradiographic localization.
    Proc Natl Acad Sci U S A Volume: 77 Page(s): 1696 - 1700
    03/01/1980 Authors: Young WS; Kuhar MJ
  • Ontogeny of muscarinic receptors in rat brain.
    Brain Res Volume: 184 Page(s): 375 - 383
    02/24/1980 Authors: Kuhar MJ; Birdsall NJ; Burgen AS; Hulme EC
  • Radiohistochemical localization of benzodiazepine receptors in rat brain.
    J Pharmacol Exp Ther Volume: 212 Page(s): 337 - 346
    02/01/1980 Authors: Young WS; Kuhar MJ
  • Autoradiographic localization of gamma-aminobutyric acid (GABA) receptors in the rat cerebellum.
    Proc Natl Acad Sci U S A Volume: 77 Page(s): 670 - 674
    01/01/1980 Authors: Palacios JM; Young WS; Kuhar MJ
  • Histochemistry of receptors.
    Adv Biochem Psychopharmacol Volume: 21 Page(s): 51 - 56
    01/01/1980 Authors: Young WS; Palacios JM; Kuhar MJ
  • The benzodiazepine receptor: anatomical aspects.
    NIDA Res Monogr Page(s): 12 - 21
    01/01/1980 Authors: Kuhar MJ
  • Anatomical localization of enkephalin immunoreactive sites in rat forebrain.
    Adv Biochem Psychopharmacol Volume: 22 Page(s): 257 - 270
    01/01/1980 Authors: Wamsley JK; Young WS; Kuhar MJ
  • LOCALIZATION OF BETA-ADRENERGIC RECEPTORS IN RAT-BRAIN BY LIGHT MICROSCOPIC AUTORADIOGRAPHY
    Volume: 39 Page(s): 593 - 593
    01/01/1980 Authors: PALACIOS JM; DEHAVEN RN; KUHAR MJ
  • NORADRENERGIC ALPHA-1 AND ALPHA-2 RECEPTORS - LIGHT MICROSCOPIC AUTORADIOGRAPHIC LOCALIZATION
    Volume: 39 Page(s): 593 - 593
    01/01/1980 Authors: YOUNG WS; KUHAR MJ
  • A new method for receptor autoradiography: [3H]opioid receptors in rat brain.
    Brain Res Volume: 179 Page(s): 255 - 270
    12/28/1979 Authors: Young WS; Kuhar MJ
  • Ontogeny of GABA and benzodiazepine receptors: effects of Triton X-100, bromide and muscimol.
    Brain Res Volume: 179 Page(s): 390 - 395
    12/28/1979 Authors: Palacios JM; Niehoff DL; Kuhar MJ
  • Autoradiographic localization of neuroleptic and dopamine receptors in the caudate-putamen and substantia nigra: effects of lesions.
    Eur J Pharmacol Volume: 60 Page(s): 229 - 235
    12/07/1979 Authors: Murrin LC; Gale K; Kuhar MJ
  • Dompamine receptors in the rat frontal cortex: an autoradiographic study.
    Brain Res Volume: 177 Page(s): 279 - 285
    11/16/1979 Authors: Murrin LC; Kuhar MJ
  • Noradrenergic alpha 1 and alpha 2 receptors: autoradiographic visualization.
    Eur J Pharmacol Volume: 59 Page(s): 317 - 319
    11/16/1979 Authors: Young WS; Kuhar MJ
  • Choline: binding studies provide some evidence for a weak, direct agonist action in brain.
    Mol Pharmacol Volume: 16 Page(s): 1084 - 1088
    11/01/1979 Authors: Palacios JM; Kuhar MJ
  • Neurotensin receptors: autoradiographic localization in rat CNS.
    Eur J Pharmacol Volume: 59 Page(s): 161 - 163
    10/26/1979 Authors: Young WS; Kuhar MJ
  • Autoradiographic localization of H1-histamine receptors in brain using 3H-mepyramine: preliminary studies.
    Eur J Pharmacol Volume: 58 Page(s): 295 - 304
    10/01/1979 Authors: Palacios JM; Young WS; Kuhar MJ
  • In vivo receptor binding: attempts to improve specific/non-specific ratios.
    Life Sci Volume: 25 Page(s): 819 - 826
    09/03/1979 Authors: Niehoff DL; Palacios JM; Kuhar MJ
  • Autoradiographic localisation of benzodiazepine receptors in the brains of humans and animals.
    Nature Volume: 280 Page(s): 391 - 394
    08/02/1979 Authors: Young WS; Kuhar MJ
  • Neuroleptic and dopamine receptors: autoradiographic localization of [3H]spiperone in rat brain.
    Brain Res Volume: 169 Page(s): 1 - 9
    06/15/1979 Authors: Klemm N; Murrin LC; Kuhar MJ
  • Post-mortem changes in high affinity choline uptake.
    J Neurochem Volume: 32 Page(s): 1487 - 1494
    05/01/1979 Authors: Klemm N; Kuhar MJ
  • Immunohistochemical mapping of enkephalin containing cell bodies, fibers and nerve terminals in the brain stem of the rat.
    Brain Res Volume: 166 Page(s): 75 - 94
    04/20/1979 Authors: Uhl GR; Goodman RR; Kuhar MJ; Childers SR; Snyder SH
  • RADIO-HISTOCHEMICAL STUDIES OF THE GABA AND BENZODIAZEPINE (BZ) RECEPTORS
    BRAIN RESEARCH BULLETIN Volume: 4 Page(s): 700 - 700
    01/01/1979 Authors: KUHAR MJ; PALACIOS JM; YOUNG WS
  • AUTO-RADIOGRAPHY OF OPIATE AND BENZODIAZEPINE RECEPTORS - INVITRO LABELING OF TISSUE-SECTIONS
    Volume: 38 Page(s): 687 - 687
    01/01/1979 Authors: YOUNG WS; KUHAR MJ
  • Histochemical localization of opiate receptors and the enkephalins.
    Adv Biochem Psychopharmacol Volume: 20 Page(s): 53 - 68
    01/01/1979 Authors: Kuhar MJ; Uhl GR
  • Autoradiographic localization of [3H]gentamicin in the proximal renal tubules of mice.
    Antimicrob Agents Chemother Volume: 15 Page(s): 131 - 133
    01/01/1979 Authors: Kuhar MJ; Mak LL; Lietman PS
  • Sodium-dependent high affinity choline uptake.
    Prog Brain Res Volume: 49 Page(s): 71 - 76
    01/01/1979 Authors: Kuhar MJ
  • AUTORADIOGRAPHIC LOCALIZATION OF HISTAMINE H1-RECEPTORS IN BRAIN
    Volume: 38 Page(s): 261 - 261
    01/01/1979 Authors: PALACIOS JM; YOUNG WS; KUHAR MJ
  • INVIVO RECEPTOR-BINDING - ATTEMPTS TO IMPROVE SPECIFIC-NON-SPECIFIC RATIOS
    LIFE SCIENCES Volume: 25 Page(s): 819 - 826
    01/01/1979 Authors: NIEHOFF DL; PALACIOS JM; KUHAR MJ
  • In situ injection of kainic acid: a new method for selectively lesioning neural cell bodies while sparing axons of passage.
    J Comp Neurol Volume: 180 Page(s): 301 - 323
    07/15/1978 Authors: Coyle JT; Molliver ME; Kuhar MJ
  • Iontophoresis of neurotensin in the area of the locus coeruleus.
    Brain Res Volume: 150 Page(s): 431 - 435
    07/14/1978 Authors: Young WS; Uhl GR; Kuhar MJ
  • Synaptosomal transport: a chloride dependence for choline, GABA, glycine and several other compounds.
    J Neurochem Volume: 31 Page(s): 251 - 256
    07/01/1978 Authors: Kuhar MJ; Zarbin MA
  • Enkephalin-containing pathway: amygdaloid efferents in the stria terminalis.
    Brain Res Volume: 149 Page(s): 223 - 228
    06/23/1978 Authors: Uhl GR; Kuhar MJ; Synder SH
  • Amino acid transport: alterations due to synaptosomal depolarization.
    Life Sci Volume: 22 Page(s): 2009 - 2016
    06/12/1978 Authors: Murrin LC; Lewis MS; Kuhar MJ
  • Histochemical localization of opiate receptors and opioid peptides.
    Fed Proc Volume: 37 Page(s): 153 - 157
    02/01/1978 Authors: Kuhar MJ
  • Presynaptic localization of opiate receptors in the vagal and accessory optic systems: an autoradiographic study.
    Neuropharmacology Volume: 17 Page(s): 65 - 71
    01/01/1978 Authors: Atweh SF; Murrin LC; Kuhar MJ
  • Opiate receptors: some anatomical and physiological aspects.
    Ann N Y Acad Sci Volume: 311 Page(s): 35 - 48
    01/01/1978 Authors: Kuhar MJ
  • Sodium-dependent, high affinity choline uptake.
    J Neurochem Volume: 30 Page(s): 15 - 21
    01/01/1978 Authors: Kuhar MJ; Murrin LC
  • Dopamine receptor binding in vivo: the feasibility of autoradiographic studies.
    Life Sci Volume: 22 Page(s): 203 - 210
    01/01/1978 Authors: Kuhar MJ; Murrin LC; Malouf AT; Klemm N
  • Enkephalin and neurotensin: immunohistochemical localization and identification of an amygdalofugal pathway.
    Adv Biochem Psychopharmacol Volume: 18 Page(s): 71 - 87
    01/01/1978 Authors: Uhl GR; Goodman RR; Kuhar MJ; Snyder SH
  • Autoradiographic localization of [3H]reserpine binding sites in rat brain.
    J Pharmacol Exp Ther Volume: 203 Page(s): 564 - 574
    12/01/1977 Authors: Murrin LC; Enna SJ; Kuhar MJ
  • Autoradiographic localization of opiate receptors in rat brain. III. The telencephalon.
    Brain Res Volume: 134 Page(s): 393 - 405
    10/14/1977 Authors: Atweh SF; Kuhar MJ
  • On the relationship between (3H)choline uptake activation and (3H)acetylcholine release.
    J Neurochem Volume: 29 Page(s): 681 - 687
    10/01/1977 Authors: Murrin LC; DeHaven RN; Kuhar MJ
  • Neurotensin: immunohistochemical localization in rat central nervous system.
    Proc Natl Acad Sci U S A Volume: 74 Page(s): 4059 - 4063
    09/01/1977 Authors: Uhl GR; Kuhar MJ; Snyder SH
  • Iontophoresis of methionine-enkephalin in the locus coeruleus area.
    Brain Res Volume: 129 Page(s): 366 - 370
    07/01/1977 Authors: Young WS; Bird SJ; Kuhar MJ
  • Autoradiographic localization of opiate receptors in rat brain. II. The brain stem.
    Brain Res Volume: 129 Page(s): 1 - 12
    06/24/1977 Authors: Atweh SF; Kuhar MJ
  • Opioid peptide enkephalin: immunohistochemical mapping in rat central nervous system.
    Proc Natl Acad Sci U S A Volume: 74 Page(s): 2167 - 2171
    05/01/1977 Authors: Simantov R; Kuhar MJ; Uhl GR; Snyder SH
  • Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla.
    Brain Res Volume: 124 Page(s): 53 - 67
    03/18/1977 Authors: Atweh SF; Kuhar MJ
  • Iontophoretic application of opiates to the locus coeruleus.
    Brain Res Volume: 122 Page(s): 523 - 533
    02/25/1977 Authors: Bird SJ; Kuhar MJ
  • Activation of high-affinity choline uptake in vitro by depolarizing agents.
    Mol Pharmacol Volume: 12 Page(s): 1082 - 1090
    11/01/1976 Authors: Murrin LC; Kuhar MJ
  • Opiate receptor: autoradiographic localization in rat brain.
    Proc Natl Acad Sci U S A Volume: 73 Page(s): 3729 - 3733
    10/01/1976 Authors: Pert CB; Kuhar MJ; Snyder SH
  • Localization of cholinergic muscarinic receptors in rat brain by light microscopic radioautography.
    Brain Res Volume: 110 Page(s): 229 - 243
    07/09/1976 Authors: Kuhar M; Yamamura HI
  • High affinity choline uptake: ionic and energy requirements.
    J Neurochem Volume: 27 Page(s): 93 - 99
    07/01/1976 Authors: Simon JR; Kuhar MJ
  • Effects of anesthetics and septal lesions and stimulation on 3H-acetylcholine formation in rat hippocampus.
    Eur J Pharmacol Volume: 37 Page(s): 311 - 319
    06/01/1976 Authors: Atweh SF; Kuhar MJ
  • Sodium-dependent high affinity choline uptake: a regulatory step in the synthesis of acetylcholine.
    J Neurochem Volume: 26 Page(s): 909 - 922
    05/01/1976 Authors: Simon JR; Atweh S; Kuhar MJ
  • The regional distribution of a morphine-like factors enkephalin in monkey brain.
    Brain Res Volume: 106 Page(s): 189 - 197
    04/16/1976 Authors: Simantov R; Kuhar MJ; Pasternak GW; Snyder SH
  • Binding of [3H] kainic acid, and analogue of Lglutamate, to brain membranes.
    J Neurochem Volume: 26 Page(s): 141 - 147
    01/01/1976 Authors: Simon JR; Contrera JF; Kuhar MJ
  • Serotonergic synaptosomes from rat hippocampus: lack of acetylcholinesterase.
    Brain Res Volume: 99 Page(s): 415 - 418
    12/05/1975 Authors: Kuhar MJ; Simon JR; Taylor N
  • Utilization of sodium-dependent high affinity choline uptake in vitro as a measure of the activity of cholinergic neurons in vivo.
    Life Sci Volume: 17 Page(s): 1535 - 1544
    11/15/1975 Authors: Atweh S; Simon JR; Kuhar MJ
  • Further evidence for cholinergic habenulo-interpeduncular neurons: pharmacologic and functional characteristics.
    Brain Res Volume: 97 Page(s): 265 - 275
    10/31/1975 Authors: Kuhar MJ; DeHaven RN; Yamamura HI; Rommel-Spacher H; Simon JR
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    Fed Proc Volume: 34 Page(s): 1915 - 1921
    09/01/1975 Authors: Snyder SH; Chang KJ; Kuhar MJ; Yamamura HI
  • Regional distribution of postsynaptic receptor binding for gamma-aminobutyric acid (GABA) in monkey brain.
    Brain Res Volume: 93 Page(s): 168 - 174
    07/25/1975 Authors: Enna SJ; Kuhar MJ; Snyder SH
  • Autoradiograhic localization of the opiate receptor in rat brain.
    Life Sci Volume: 16 Page(s): 1849 - 1853
    06/15/1975 Authors: Pert CB; Kuhar MJ; Snyder SH
  • Inhibition of synaptosomal uptake of choline by various choline analogs.
    Biochem Pharmacol Volume: 24 Page(s): 1139 - 1142
    05/15/1975 Authors: Simon JR; Mittag TW; Kuhar JM
  • Impulse-flow regulation of high affinity choline uptake in brain cholinergic nerve terminals.
    Nature Volume: 255 Page(s): 162 - 163
    05/08/1975 Authors: Simon JR; Kuhar MG
  • Light autoradiographic localisation of cholinergic muscarinic receptors in rat brain by specific binding of a potent antagonist.
    Nature Volume: 253 Page(s): 560 - 561
    02/13/1975 Authors: Kuhar MJ; Yamamura HI
  • ATTEMPTS AT IDENTIFYING GLUTAMATE RECEPTOR IN BRAIN-TISSUE BY BINDING RADIOLABELED KAINIC ACID
    Volume: 34 Page(s): 294 - 294
    01/01/1975 Authors: SIMON JR; KUHAR MJ
  • Effects of drugs and axotomy on acetylcholine levels in central cholinergic neurons.
    Naunyn Schmiedebergs Arch Pharmacol Volume: 291 Page(s): 17 - 21
    01/01/1975 Authors: Rommelspacher H; Kuhar MJ
  • CHOLINERGIC MUSCARINIC RECEPTOR - BIOCHEMICAL AND LIGHT AUTORADIOGRAPHIC LOCALIZATION IN BRAIN
    CROATICA CHEMICA ACTA Volume: 47 Page(s): 475 - 488
    01/01/1975 Authors: YAMAMURA HI; CHANG KJ; KUHAR MJ; SNYDER SH
  • D & L amphetamine stereoisomers: comparative potencies in affecting the firing of central dopaminergic and noradrenergic neurons.
    Psychopharmacol Commun Volume: 1 Page(s): 177 - 190
    01/01/1975 Authors: Bunney BS; Walters JR; Kuhar MJ; Roth RH; Aghajanian GK
  • Effects of dopaminergic drugs and acute medial forebrain bundle lesions on striatal acetylcholine levels.
    Life Sci Volume: 16 Page(s): 65 - 70
    01/01/1975 Authors: Rommelspacher H; Kuhar MJ
  • Proceedings: Effect of drugs on alterations of neuronal impulse flow of a central cholinergic tract.
    Naunyn Schmiedebergs Arch Pharmacol Volume: 287 Suppl Page(s): R10
    01/01/1975 Authors: Rommelspacher H; Kuhar MJ
  • Effects of electrical stimulation on acetylcholine levels in central cholinergic nerve terminals.
    Brain Res Volume: 81 Page(s): 243 - 251
    12/06/1974 Authors: Rommelspacher H; Kuhar MJ
  • The binding of vinblastine to tubulin and to particulate fractions of mammalian brain.
    Cancer Res Volume: 34 Page(s): 3180 - 3186
    12/01/1974 Authors: Owellen RJ; Donigian DW; Hartke CA; Dickerson RM; Kuhar MJ
  • In vivo identification of muscarinic cholinergic receptor binding in rat brain.
    Brain Res Volume: 80 Page(s): 170 - 176
    11/08/1974 Authors: Yamamura HI; Kuhar MJ; Snyder SH
  • Action of hemicholinium-3 on cholinergic nerve terminals after alteration of neuronal impulse flow.
    Neuropharmacology Volume: 13 Page(s): 1015 - 1023
    11/01/1974 Authors: Rommelspacher H; Goldberg AM; Kuhar MJ
  • Brain histamine alterations after hypothalamic isolation.
    Brain Res Volume: 78 Page(s): 144 - 151
    09/20/1974 Authors: Dismukes K; Kuhar MJ; Snyder SH
  • Acetylcholinesterase-staining synaptosomes from rat hippocampus: relative frequency and tentative estimation of internal concentration of free or 'labile bound' acetylcholine.
    Brain Res Volume: 77 Page(s): 85 - 96
    08/30/1974 Authors: Kuhar MJ; Rommelspacher H
  • The subsynaptosomal localization of histamine, histidine decarboxylase and histamine methyltransferase in rat hypothalamus.
    J Neurochem Volume: 23 Page(s): 37 - 45
    07/01/1974 Authors: Snyder SH; Brown B; Kuhar MJ
  • Acetylcholine uptake: lack of association with cholinergic neurons.
    J Neurochem Volume: 22 Page(s): 1135 - 1137
    06/01/1974 Authors: Kuhar MJ; Simon JR
  • Release of acetylcholine from hippocampal slices by potassium depolarization: dependence on high affinity choline uptake.
    Brain Res Volume: 70 Page(s): 372 - 376
    04/19/1974 Authors: Mulder AH; Yamamura HI; Kuhar MJ; Snyder SH
  • Subcellular localization of dopamine beta-hydroxylase and endogenous norepinephrine in the rat hypothalamus.
    Brain Res Volume: 65 Page(s): 475 - 487
    01/18/1974 Authors: Coyle JT; Kuhar MJ
  • Serotonin neurons: a synaptic mechanism for the reuptake of serotonin.
    Adv Biochem Psychopharmacol Volume: 10 Page(s): 287 - 295
    01/01/1974 Authors: Kuhar MJ; Aghajanian GK; Roth RH
  • Neurotransmitter uptake: a tool in identifying neurotransmitter-specific pathways.
    Life Sci Volume: 13 Page(s): 1623 - 1634
    12/16/1973 Authors: Kuhar MJ
  • Regional distribution of opiate receptor binding in monkey and human brain.
    Nature Volume: 245 Page(s): 447 - 450
    10/26/1973 Authors: Kuhar MJ; Pert CB; Snyder SH
  • Choline and acetylcholine: regional distribution and effect of degeneration of cholinergic nerve terminals in the rat hippocampus.
    Neuropharmacology Volume: 12 Page(s): 819 - 823
    09/01/1973 Authors: Sethy VH; Roth RH; Kuhar MJ; Van Woert MH
  • Cholinergic neurons: effect of acute septal lesion on acetylcholine and choline content of rat hippocampus.
    Brain Res Volume: 55 Page(s): 481 - 484
    06/15/1973 Authors: Sethy VH; Kuhar MJ; Roth RH; Van Woert MH; Aghajanian GK
  • Serotonin-containing neuronal perikarya and terminals: differential effects of P-chlorophenylalanine.
    Brain Res Volume: 54 Page(s): 85 - 101
    05/17/1973 Authors: Aghajanian GK; Kuhar MJ; Roth RH
  • Selective accumulation of 3 H-serotonin by nerve terminals of raphe neurones: an autoradiographic study.
    Nat New Biol Volume: 241 Page(s): 187 - 189
    02/07/1973 Authors: Kuhar MJ; Aghajanian GK
  • Choline: selective accumulation by central cholinergic neurons.
    J Neurochem Volume: 20 Page(s): 581 - 593
    02/01/1973 Authors: Kuhar MJ; Sethy VH; Roth RH; Aghajanian GK
  • Effect of gamma-hydroxybutyrate and gamma-butyrolactone on dopamine synthesis and uptake by rat striatum.
    Biochem Pharmacol Volume: 21 Page(s): 2649 - 2652
    10/01/1972 Authors: Bustos G; Kuhar MJ; Roth RH
  • Tryptophan hydroxylase activity and synaptosomal uptake of serotonin in discrete brain regions after midbrain raphe lesions: correlations with serotonin levels and histochemical fluorescence.
    Brain Res Volume: 44 Page(s): 165 - 176
    09/15/1972 Authors: Kuhar MJ; Aghajanian GK; Roth RH
  • Synthesis of catecholamines in the locus coeruleus from 3 H-tyrosine in vivo.
    Biochem Pharmacol Volume: 21 Page(s): 2280 - 2282
    08/15/1972 Authors: Kuhar MJ; Roth RH; Aghajanian GK
  • Synaptosomes from forebrains of rats with midbrain raphe lesions: selective reduction of serotonin uptake.
    J Pharmacol Exp Ther Volume: 181 Page(s): 36 - 45
    04/01/1972 Authors: Kuhar MJ; Roth RH; Aghajanian GK
  • Selective reduction of tryptophan hydroxylase activity in rat forebrain after midbrain raphe lesions.
    Brain Res Volume: 35 Page(s): 167 - 176
    12/10/1971 Authors: Kuhar MJ; Roth RH; Aghajanian GK
  • The subcellular localization of histamine and histamine methyltransferase in rat brain.
    J Neurochem Volume: 18 Page(s): 1515 - 1527
    08/01/1971 Authors: Kuhar MJ; Taylor KM; Snyder SH
  • A unique synaptosomal fraction, which accumulates glutamic and aspartic acids, in brain tissue.
    Proc Natl Acad Sci U S A Volume: 68 Page(s): 1102 - 1106
    06/01/1971 Authors: Wofsey AR; Kuhar MJ; Snyder SH
  • The subcellular distribution of endogenous and exogenous serotonin in brain tissue: comparison of synaptosomes storing serotonin, norepinephrine, and gamma-aminobutyric acid.
    J Neurochem Volume: 18 Page(s): 333 - 343
    03/01/1971 Authors: Kuhar MJ; Shaskan EG; Snyder SH
  • A possible mechanism for the pathogenic action of monosodium glutamate.
    Res Commun Chem Pathol Pharmacol Volume: 2 Page(s): 95 - 97
    01/01/1971 Authors: Kuhar MJ
  • Neurotransmitter-specific synaptosomes in rat corpus striatum: morphological variations.
    Proc Natl Acad Sci U S A Volume: 68 Page(s): 155 - 159
    01/01/1971 Authors: Gfeller E; Kuhar MJ; Snyder SH
  • Separation of synaptosomes storing catecholamines and gamma-aminobutyric acid in rat corpus striatum.
    Brain Res Volume: 21 Page(s): 405 - 417
    07/29/1970 Authors: Kuhar MJ; Green AI; Snyder SH; Gfeller E
  • The subcellular distribution of free H3-glutamic acid in rat cerebral cortical slices.
    J Pharmacol Exp Ther Volume: 171 Page(s): 141 - 152
    01/01/1970 Authors: Kuhar MJ; Snyder SH
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