Michael Kuhar PhD
Overview
Michael Kuhar, PhD, is a Researcher at Emory National Primate Research Center, Candler Professor of Neuropharmacology at Emory University School of Medicine and Senior Fellow in the Center for Ethics at Emory.
Dr. Kuhar has spent more than four decades as a neuroscience and neuropharmacology researcher. His studies have focused on the cellular and anatomical bases of addiction in order to pave the way for a new class of drugs to target addiction and obesity through a better understanding of CART peptides. These specific peptides are neurotransmitters that have been implicated in the regulation of feeding, body weight, drug reward and stress.
With his more than 900 scientific publications, Dr. Kuhar is the most cited researcher at Emory. He has trained more than 60 students, research fellows and visitors, and he is the author of The Addicted Brain, Why we abuse drugs, alcohol, and nicotine (2012 Pearson Education/FT Press) and The Art and Ethics of Being a Good Colleague (2013 CreateSpace Independent Publishing Platform). His latest book is the basis for the "Michael Kuhar on Getting Collegial" article in the Spring 2014 issue of Emory Magazine.
In 2011, Dr. Kuhar received the Nathan B. Eddy Memorial Award from the College on Problems of Drug Dependence to honor his lifetime achievements in research that have advanced the understanding of drug dependence.
A recent interest of Dr. Kuhar's is working with Tibetan monks who are part of the community of the Dalai Lama in Exile. Dr. Kuhar is a member of the Emory-Tibet Science Initiative (ETSI) and taught information about neurotransmission and drug addiction as part of a Neuroscience course for Tibetan Buddhist monks and nuns. Dr. Kuhar has traveled to India twice as part of the ETSI.
This summer, Dr. Kuhar is offering an expert glimpse into addiction research through Coursera, an Emory partner for MOOCs (massive open online courses). The course, "The Addicted Brain," examines addiction to drugs and other behaviors. In the course, Dr. Kuhar describes what happens in the brain and how this information helps us deal with and overcome addiction.
Academic Appointment
- Research Professor, Emory National Primate Research Center
- Candler Professor of Neuropharmacology, Pharmacology, Emory University School of Medicine
Education
Degrees
- PhD from Johns Hopkins University
Research
Publications
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CART peptide in the nucleus accumbens regulates psychostimulants: Correlations between psychostimulant and CART peptide effects.
Neuroscience Volume: 348 Page(s): 135 - 142
04/21/2017 Authors: Job MO; Kuhar MJ -
CART Peptide Regulates Psychostimulant-Induced Activity and Exhibits a Rate Dependency.
J Drug Alcohol Res Volume: 6
01/01/2017 Authors: Kuhar MJ; Job MO -
Receptor autoradiography as an aid in explaining drug action
Imaging Drug Action in the Brain Page(s): 49 - 60
01/01/2017 Authors: Kuhar MJ; De Souza EB -
CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.
Diabetologia Volume: 59 Page(s): 1928 - 1937
09/01/2016 Authors: Abels M; Riva M; Bennet H; Ahlqvist E; Dyachok O; Nagaraj V; Shcherbina L; Fred RG; Poon W; Srhede-Winzell M -
Letter from the editor-in-chief: Irreproducible results and NIH actions
Journal of Drug and Alcohol Research Volume: 5
04/25/2016 Authors: Kuhar MJ -
Behavioral effects of naloxone and LSD
Endorphins in Mental Health Research Page(s): 407 - 415
01/14/2016 Authors: Perez-Cruet J; Volavka J; Mallya A; Baig S; Toga A -
CART Peptides and Drugs of Abuse: A Review of Recent Progress.
J Drug Alcohol Res Volume: 5
01/01/2016 Authors: Kuhar MJ -
Meet our editorial board member
Current Molecular Pharmacology Volume: 8 Page(s): 1
09/01/2015 Authors: Kuhar MJ -
Meet our editorial board member
Current Molecular Pharmacology Volume: 8 Page(s): 1
01/01/2015 Authors: Kuhar MJ -
Cocaine-and-Amphetamine Regulated Transcript (CART) peptide attenuates dopamine- and cocaine-mediated locomotor activity in both male and female rats: lack of sex differences.
Neuropeptides Volume: 48 Page(s): 75 - 81
04/01/2014 Authors: Job MO; Perry J; Shen LL; Kuhar MJ -
A novel validated and sensitive LC-MS/MS method in monkey plasma for simultaneous determination of methamphetamine and its metabolites in methamphetamine-treated monkey plasma
Volume: 9 Page(s): 14 - 15
03/01/2014 Authors: Earla R; Bosinger S; Shah A; Gangwani MR; Nookala A; Liu X; Cao L; Kuhar MJ; Kumar S; Fox HS -
Letter from the Editor-in-Chief: Irreproducible Results.
J Drug Alcohol Res Volume: 3
01/01/2014 Authors: Kuhar MJ -
Collegial ethics: supporting our colleagues.
Sci Eng Ethics Volume: 19 Page(s): 677 - 684
09/01/2013 Authors: Kuhar MJ; Cross D -
The inhibition of cocaine-induced locomotor activity by CART 55-102 is lost after repeated cocaine administration.
Neurosci Lett Volume: 550 Page(s): 179 - 183
08/29/2013 Authors: Job MO; Shen LL; Kuhar MJ -
Affinity labeling of membrane receptors using tissue-penetrating radiations.
Biomed Res Int Volume: 2013 Page(s): 503095
01/01/2013 Authors: Wong FC; Boja J; Ho B; Kuhar MJ; Wong DF -
The Effects of Drug Abuse on the Human Nervous System
Page(s): 1 - 609
01/01/2013 Authors: Madras B; Kuhar M -
Intra-accumbal administration of shRNAs against CART peptides cause increases in body weight and cocaine-induced locomotor activity in rats.
Brain Res Volume: 1482 Page(s): 47 - 54
10/30/2012 Authors: Job MO; Licata J; Hubert GW; Kuhar MJ -
Region- and sex-specific changes in CART mRNA in rat hypothalamic nuclei induced by forced swim stress.
Brain Res Volume: 1479 Page(s): 62 - 71
10/15/2012 Authors: Balkan B; Gozen O; Koylu EO; Keser A; Kuhar MJ; Pogun S -
The cocaine- and amphetamine-regulated transcript mediates ligand-independent activation of ER, and is an independent prognostic factor in node-negative breast cancer.
Oncogene Volume: 31 Page(s): 3483 - 3494
07/26/2012 Authors: Brennan DJ; O'Connor DP; Laursen H; McGee SF; McCarthy S; Zagozdzon R; Rexhepaj E; Culhane AC; Martin FM; Duffy MJ -
Forced swim stress elicits region-specific changes in CART expression in the stress axis and stress regulatory brain areas.
Brain Res Volume: 1432 Page(s): 56 - 65
01/13/2012 Authors: Balkan B; Keser A; Gozen O; Koylu EO; Dagci T; Kuhar MJ; Pogun S -
Intraperitoneal Administration of CART 55-102 Inhibits Psychostimulant-Induced Locomotion.
J Drug Alcohol Res Volume: 1
01/01/2012 Authors: Job MO; Kuhar MJ -
Collegial ethics: what, why and how.
Drug Alcohol Depend Volume: 119 Page(s): 235 - 238
12/15/2011 Authors: Kuhar MJ -
CART peptide stimulation of G protein-mediated signaling in differentiated PC12 cells: identification of PACAP 6-38 as a CART receptor antagonist.
Neuropeptides Volume: 45 Page(s): 351 - 358
10/01/2011 Authors: Lin Y; Hall RA; Kuhar MJ -
Preface
Current Neuropharmacology Volume: 9 Page(s): 1
03/30/2011 Authors: Ali SF; Kim HC; Koob G; Onaivi E; Kuhar MJ -
CART Peptides Regulate Psychostimulants and May be Endogenous Antidepressants.
Curr Neuropharmacol Volume: 9 Page(s): 12 - 16
03/01/2011 Authors: Job MO; McNamara IM; Kuhar MJ -
Understanding the Global Problem of Drug Addiction is a Challenge for IDARS Scientists.
Curr Neuropharmacol Volume: 9 Page(s): 2 - 7
03/01/2011 Authors: Ali SF; Onaivi ES; Dodd PR; Cadet JL; Schenk S; Kuhar MJ; Koob GF -
New Research Frontiers and Advances in Drug Addiction PREFACE
CURRENT NEUROPHARMACOLOGY Volume: 9 Page(s): 1 - 1
03/01/2011 Authors: Ali SF; Onaivi E; Kim H-C; Kuhar MJ; Koob G -
CART peptide inhibits locomotor activity induced by simultaneous stimulation of D1 and D2 receptors, but not by stimulation of individual dopamine receptors.
Synapse Volume: 65 Page(s): 1 - 7
01/01/2011 Authors: Moffett MC; Song J; Kuhar MJ -
Developing and communicating responsible data management policies to trainees and colleagues.
Sci Eng Ethics Volume: 16 Page(s): 753 - 762
12/01/2010 Authors: Frugoli J; Etgen AM; Kuhar M -
Chromatin immunoprecipitation assays revealed CREB and serine 133 phospho-CREB binding to the CART gene proximal promoter.
Brain Res Volume: 1344 Page(s): 1 - 12
07/16/2010 Authors: Rogge GA; Shen L-L; Kuhar MJ -
Wake promoting effects of cocaine and amphetamine-regulated transcript (CART).
Neuropeptides Volume: 44 Page(s): 241 - 246
06/01/2010 Authors: Keating GL; Kuhar MJ; Bliwise DL; Rye DB -
Developing and Communicating Responsible Data Management Policies to Trainees and Colleagues.
Sci Eng Ethics
04/27/2010 Authors: Frigoli J; Etgen AM; Kuhar M -
CREB regulation of the CART gene in the rat nucleus accumbens and GH3 cultured cells
Volume: 24
04/01/2010 Authors: Rogge GA; Jones DC; Nestler E; Kuhar MJ -
Conversation with Michael Kuhar.
Addiction Volume: 105 Page(s): 593 - 600
04/01/2010 Authors: Kuhar M -
CART peptide may be an endogenous antidepressant
Volume: 24
04/01/2010 Authors: Job M; McNamera I; Kuhar M -
Measuring levels of proteins by various technologies: can we learn more by measuring turnover?
Biochem Pharmacol Volume: 79 Page(s): 665 - 668
03/01/2010 Authors: Kuhar MJ -
CART peptides: regulators of body weight, reward and other functions (vol 9, pg 747, 2008)
NATURE REVIEWS NEUROSCIENCE Volume: 11
03/01/2010 Authors: Rogge G; Jones D; Hubert GW; Lin Y; Kuhar MJ -
Contributions of basic science to understanding addiction
BIOSOCIETIES Volume: 5 Page(s): 25 - 35
03/01/2010 Authors: Kuhar MJ -
Erratum: CART peptides: Regulators of body weight, reward and other functions (Nature Reviews Neuroscience (2008) 9 (747-758))
Nature Reviews Neuroscience Volume: 11 Page(s): 218
03/01/2010 Authors: Rogge G; Jones D; Hubert GW; Lin Y; Kuhar MJ -
Cocaine and amphetamine-regulated transcript-containing neurons in the nucleus accumbens project to the ventral pallidum in the rat and may inhibit cocaine-induced locomotion.
Neuroscience Volume: 165 Page(s): 179 - 187
01/13/2010 Authors: Hubert GW; Manvich DF; Kuhar MJ -
Blacklisting among scientists.
Synapse Volume: 63 Page(s): 539 - 540
07/01/2009 Authors: Kuhar MJ -
Regulation of cocaine- and amphetamine-regulated transcript mRNA expression by calcium-mediated signaling in GH3 cells.
Neuroscience Volume: 160 Page(s): 339 - 347
05/05/2009 Authors: Jones DC; Lakatos A; Rogge GA; Kuhar MJ -
On the use of protein turnover and half-lives.
Neuropsychopharmacology Volume: 34 Page(s): 1172 - 1173
04/01/2009 Authors: Kuhar MJ -
Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo.
Brain Res Volume: 1251 Page(s): 42 - 52
01/28/2009 Authors: Rogge GA; Jones DC; Green T; Nestler E; Kuhar MJ -
NEONATAL COLD PANNICULITIS INDUCED BY ICE BAG TREATMENT FOR SUPRAVENTRICULAR TACHYCARDIA
Volume: 36 Page(s): 119 - 119
01/01/2009 Authors: Kuhar M; Moores W; Hinds B -
Development of the dopamine transporter selective RTI-336 as a pharmacotherapy for cocaine abuse
Drug Addiction: From Basic Research to Therapy Page(s): 179 - 191
12/01/2008 Authors: Carroll FI; Howard JL; Howell LL; Fox BS; Kuhar MJ -
Cocaine- and amphetamine-regulated transcript peptides play a role in drug abuse and are potential therapeutic targets
Drug Addiction: From Basic Research to Therapy Page(s): 101 - 112
12/01/2008 Authors: Kuhar MJ; Jaworski JN; Hubert GW; Philpot KB; Dominguez G -
CART peptides: regulators of body weight, reward and other functions.
Nat Rev Neurosci Volume: 9 Page(s): 747 - 758
10/01/2008 Authors: Rogge G; Jones D; Hubert GW; Lin Y; Kuhar MJ -
On blacklisting in science.
Sci Eng Ethics Volume: 14 Page(s): 301 - 303
09/01/2008 Authors: Kuhar MJ -
Frequency of maternal licking and grooming correlates negatively with vulnerability to cocaine and alcohol use in rats.
Pharmacol Biochem Behav Volume: 90 Page(s): 497 - 500
09/01/2008 Authors: Francis DD; Kuhar MJ -
Unique responses of midbrain CART neurons in macaques to ovarian steroids.
Brain Res Volume: 1227 Page(s): 76 - 88
08/28/2008 Authors: Lima FB; Henderson JA; Reddy AP; Tokuyama Y; Hubert GW; Kuhar MJ; Bethea CL -
Injection of CART (cocaine- and amphetamine-regulated transcript) peptide into the nucleus accumbens reduces cocaine self-administration in rats.
Behav Brain Res Volume: 191 Page(s): 266 - 271
08/22/2008 Authors: Jaworski JN; Hansen ST; Kuhar MJ; Mark GP -
Cocaine administration increases the fraction of CART cells in the rat nucleus accumbens that co-immunostain for c-Fos.
Neuropeptides Volume: 42 Page(s): 339 - 343
06/01/2008 Authors: Hubert GW; Kuhar MJ -
High dose CART peptide induces abnormal EEG activity and behavioral seizures.
Neuropeptides Volume: 42 Page(s): 199 - 204
04/01/2008 Authors: Keating GL; Kuhar MJ; Rye DB -
Periodic fever syndrome with aphthous stomatitis, pharyngitis and cervical adenopathy treated with ketotifen - a case report
Volume: 26 Page(s): 213 - 213
03/01/2008 Authors: Toplak N; Glavnik V; Kuhar M; Avcin T -
CART receptor binding in primary cell cultures of the rat nucleus accumbens.
Synapse Volume: 62 Page(s): 122 - 127
02/01/2008 Authors: Jones DC; Kuhar MJ -
CART peptides as modulators of dopamine and psychostimulants and interactions with the mesolimbic dopaminergic system.
Biochem Pharmacol Volume: 75 Page(s): 57 - 62
01/01/2008 Authors: Hubert GW; Jones DC; Moffett MC; Rogge G; Kuhar MJ -
CART deficiency increases body weight but does not alter bone strength.
J Musculoskelet Neuronal Interact Volume: 8 Page(s): 146 - 153
01/01/2008 Authors: Bartell SM; Isales CM; Baile CA; Kuhar MJ; Hamrick MW -
Increased metabolism in the R6/2 mouse model of Huntington's disease.
Neurobiol Dis Volume: 29 Page(s): 41 - 51
01/01/2008 Authors: van der Burg JMM; Bacos K; Wood NI; Lindqvist A; Wierup N; Woodman B; Wamsteeker JI; Smith R; Deierborg T; Kuhar MJ -
Annals of the New York Academy of Sciences: Preface
Volume: 1139
01/01/2008 Authors: Ali SF; Kuhar MJ -
Synthesis, monoamine transporter binding, properties, and functional monoamine uptake activity of 3beta-[4-methylphenyl and 4-chlorophenyl]-2 beta-[5-(substituted phenyl)thiazol-2-yl]tropanes.
J Med Chem Volume: 50 Page(s): 3686 - 3695
07/26/2007 Authors: Gong PK; Blough BE; Brieaddy LE; Huang X; Kuhar MJ; Navarro HA; Carroll FI -
Sex differences in the regulation of cocaine and amphetamine-regulated transcript expression in hypothalamic nuclei of rats by forced swim stress.
Synapse Volume: 61 Page(s): 561 - 568
07/01/2007 Authors: Gozen O; Balkan B; Yararbas G; Koylu EO; Kuhar MJ; Pogun S -
CART-peptide immunoreactivity in enteric nerves in patients with Hirschsprung's disease.
Eur J Pediatr Surg Volume: 17 Page(s): 184 - 189
06/01/2007 Authors: Gunnarsdttir A; Wierup N; Larsson LT; Kuhar MJ; Ekblad E -
Intra-VTA CART 55-102 reduces the locomotor effect of systemic cocaine in rats: an isobolographic analysis.
Neuropeptides Volume: 41 Page(s): 65 - 72
04/01/2007 Authors: Jaworski JN; Kimmel HL; Mitrano DA; Tallarida RJ; Kuhar MJ -
Maternal separation alters drug intake patterns in adulthood in rats.
Biochem Pharmacol Volume: 73 Page(s): 321 - 330
02/01/2007 Authors: Moffett MC; Vicentic A; Kozel M; Plotsky P; Francis DD; Kuhar MJ -
Effects of dopamine transporter selective 3-phenyltropane analogs on locomotor activity, drug discrimination, and cocaine self-administration after oral administration.
Eur J Pharmacol Volume: 553 Page(s): 149 - 156
12/28/2006 Authors: Carroll FI; Fox BS; Kuhar MJ; Howard JL; Pollard GT; Schenk S -
Colocalization of CART peptide with prodynorphin and dopamine D1 receptors in the rat nucleus accumbens.
Neuropeptides Volume: 40 Page(s): 409 - 415
12/01/2006 Authors: Hubert GW; Kuhar MJ -
CART Peptide And Ingestive Behavior
Handbook of Biologically Active Peptides Page(s): 913 - 918
12/01/2006 Authors: Philpot KB; Kuhar MJ -
CART, a new player in the regulation of islet hormone secretion
Volume: 49 Page(s): 313 - 314
09/01/2006 Authors: Wierup N; Bjorkqvist M; Mulder H; Kuhar MJ; Ahren B; Sundler F -
Cocaine and amphetamine regulated transcript (CART) and the stress response.
Peptides Volume: 27 Page(s): 1956 - 1969
08/01/2006 Authors: Koylu EO; Balkan B; Kuhar MJ; Pogun S -
Intrathecal CART (55-102) attenuates hyperlagesia and allodynia in a mouse model of neuropathic but not inflammatory pain.
Peptides Volume: 27 Page(s): 2019 - 2023
08/01/2006 Authors: Damaj MI; Zheng J; Martin BR; Kuhar MJ -
Introductory note
Peptides Volume: 27 Page(s): 1911 - 1912
08/01/2006 Authors: Kuhar MJ -
Studies of cocaine- and amphetamine-regulated transcript (CART) knockout mice.
Peptides Volume: 27 Page(s): 2037 - 2045
08/01/2006 Authors: Moffett M; Stanek L; Harley J; Rogge G; Asnicar M; Hsiung H; Kuhar M -
Should Codes of Ethics include expectations of others?
Sci Eng Ethics Volume: 12 Page(s): 413 - 414
07/01/2006 Authors: Kuhar MJ -
Modeling the onset of drug dependence: a consideration of the requirement for protein synthesis.
J Theor Biol Volume: 240 Page(s): 531 - 537
06/21/2006 Authors: Joyce AR; Easterling K; Holtzman SG; Kuhar MJ -
Maternal separation alters serotonergic transporter densities and serotonergic 1A receptors in rat brain.
Neuroscience Volume: 140 Page(s): 355 - 365
06/19/2006 Authors: Vicentic A; Francis D; Moffett M; Lakatos A; Rogge G; Hubert GW; Harley J; Kuhar MJ -
Regulation of CART mRNA in the rat nucleus accumbens via D3 dopamine receptors.
Neuropharmacology Volume: 50 Page(s): 858 - 864
06/01/2006 Authors: Hunter RG; Jones D; Vicentic A; Hue G; Rye D; Kuhar MJ -
CART expression in limbic regions of rat brain following forced swim stress: sex differences.
Neuropeptides Volume: 40 Page(s): 185 - 193
06/01/2006 Authors: Balkan B; Gozen O; Yararbas G; Koylu EO; Akinturk S; Kuhar MJ; Pogun S -
Maternal separation and handling affects cocaine self-administration in both the treated pups as adults and the dams.
J Pharmacol Exp Ther Volume: 317 Page(s): 1210 - 1218
06/01/2006 Authors: Moffett MC; Harley J; Francis D; Sanghani SP; Davis WI; Kuhar MJ -
Cocaine-amphetamine-regulated transcript expression in the rat nucleus accumbens is regulated by adenylyl cyclase and the cyclic adenosine 5'-monophosphate/protein kinase a second messenger system.
J Pharmacol Exp Ther Volume: 317 Page(s): 454 - 461
04/01/2006 Authors: Jones DC; Kuhar MJ -
CART peptides as modulators of mesolimbic dopamine and psychostimulants
Volume: 40 Page(s): 148 - 148
04/01/2006 Authors: Kuhar MJ -
Development of the dopamine transporter selective RTI-336 as a pharmacotherapy for cocaine abuse.
AAPS J Volume: 8 Page(s): E196 - E203
03/24/2006 Authors: Carroll FI; Howard JL; Howell LL; Fox BS; Kuhar MJ -
CART peptide receptors: Specific binding in AtT20 cells
Volume: 20 Page(s): A685 - A685
03/06/2006 Authors: Vicentic A; Lakatos A; Kuhar M; Ntl Y -
CART regulates islet hormone secretion and is expressed in the beta-cells of type 2 diabetic rats.
Diabetes Volume: 55 Page(s): 305 - 311
02/01/2006 Authors: Wierup N; Bjrkqvist M; Kuhar MJ; Mulder H; Sundler F -
Cart peptide promotes wake and seizure activity in the rat
Volume: 29 Page(s): A22 - A22
01/01/2006 Authors: Keating GL; Kuhar MJ; Vicentic A; Rye DB -
Adolescents carrying a missense mutation in the CART gene exhibit increased anxiety and depression.
Depress Anxiety Volume: 23 Page(s): 90 - 92
01/01/2006 Authors: Miraglia del Giudice E; Santoro N; Fiumani P; Dominguez G; Kuhar MJ; Perrone L -
The Leu34Phe ProCART mutation leads to cocaine- and amphetamine-regulated transcript (CART) deficiency: a possible cause for obesity in humans.
Endocrinology Volume: 147 Page(s): 39 - 43
01/01/2006 Authors: Yanik T; Dominguez G; Kuhar MJ; Del Giudice EM; Loh YP -
CART (cocaine- and amphetamine-regulated transcript) peptide receptors: specific binding in AtT20 cells.
Eur J Pharmacol Volume: 528 Page(s): 188 - 189
12/28/2005 Authors: Vicentic A; Lakatos A; Kuhar MJ -
Cocaine-induced alterations in nucleus accumbens ionotropic glutamate receptor subunits in human and non-human primates.
J Neurochem Volume: 95 Page(s): 1785 - 1793
12/01/2005 Authors: Hemby SE; Tang W; Muly EC; Kuhar MJ; Howell L; Mash DC -
Synthesis and monoamine transporter binding properties of 2,3-diaryltropanes.
J Med Chem Volume: 48 Page(s): 7437 - 7444
11/17/2005 Authors: Kotturi SV; Jiang S; Chang A-C; Abraham P; Navarro HA; Kuhar MJ; Carroll FI -
Cocaine- and amphetamine-regulated transcript peptides play a role in drug abuse and are potential therapeutic targets.
AAPS J Volume: 7 Page(s): E259 - E265
09/02/2005 Authors: Kuhar MJ; Jaworski JN; Hubert GW; Philpot KB; Dominguez G -
Cocaine- and amphetamine-regulated transcript (CART) peptide activates the extracellular signal-regulated kinase (ERK) pathway in AtT20 cells via putative G-protein coupled receptors.
Neurosci Lett Volume: 384 Page(s): 198 - 202
08/12/2005 Authors: Lakatos A; Prinster S; Vicentic A; Hall RA; Kuhar MJ -
Effects of early maternal separation on ethanol intake, GABA receptors and metabolizing enzymes in adult rats.
Psychopharmacology (Berl) Volume: 181 Page(s): 8 - 15
08/01/2005 Authors: Jaworski JN; Francis DD; Brommer CL; Morgan ET; Kuhar MJ -
Colocalization of CART with substance P but not enkephalin in the rat nucleus accumbens.
Brain Res Volume: 1050 Page(s): 8 - 14
07/19/2005 Authors: Hubert GW; Kuhar MJ -
CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight.
Regul Pept Volume: 129 Page(s): 203 - 211
07/15/2005 Authors: Wierup N; Richards WG; Bannon AW; Kuhar MJ; Ahrn B; Sundler F -
The effects of cocaine on CART expression in the rat nucleus accumbens: a possible role for corticosterone.
Eur J Pharmacol Volume: 517 Page(s): 45 - 50
07/04/2005 Authors: Hunter RG; Vicentic A; Rogge G; Kuhar MJ -
Species differences in brain distribution of CART mRNA and CART peptide between prairie and meadow voles.
Brain Res Volume: 1048 Page(s): 12 - 23
06/28/2005 Authors: Hunter RG; Lim MM; Philpot KB; Young LJ; Kuhar MJ -
Synthesis and monoamine transporter binding properties of 3alpha-(substituted phenyl)nortropane-2beta-carboxylic acid methyl esters. Norepinephrine transporter selective compounds.
J Med Chem Volume: 48 Page(s): 3852 - 3857
06/02/2005 Authors: Carroll FI; Tyagi S; Blough BE; Kuhar MJ; Navarro HA -
Synthesis and monoamine transporter binding properties of 3beta-(3',4'-disubstituted phenyl)tropane-2beta-carboxylic acid methyl esters.
J Med Chem Volume: 48 Page(s): 2767 - 2771
04/21/2005 Authors: Carroll FI; Blough BE; Nie Z; Kuhar MJ; Howell LL; Navarro HA -
Synthesis, structural identification, and ligand binding of tropane ring analogs of paroxetine and an unexpected aza-bicyclo[3.2.2]nonane rearrangement product.
Bioorg Med Chem Volume: 13 Page(s): 2439 - 2449
04/01/2005 Authors: Runyon SP; Burgess JP; Abraham P; Keverline-Frantz KI; Flippen-Anderson J; Deschamps J; Lewin AH; Navarro HA; Boja JW; Kuhar MJ -
CART receptor is coupled to Gi/o protein and MAP kinase activation in AtT20 cells
Volume: 19 Page(s): A1548 - A1548
03/07/2005 Authors: Lakatos A; Vicentic A; Hall RA; Prinster S; Kuhar MJ -
CART expression in the rat nucleus accumbens is regulated by the PKA/CREB pathway
Volume: 19 Page(s): A509 - A509
03/04/2005 Authors: Jones DC; Kuhar MJ -
CART peptide identification in monkey and human CSF
Volume: 19 Page(s): A509 - A509
03/04/2005 Authors: Vicentic A; Dominguez G; Rye D; Kuhar M -
Effect of corticosterone on CART peptide levels in rat blood.
Peptides Volume: 26 Page(s): 531 - 533
03/01/2005 Authors: Vicentic A; Hunter RG; Kuhar MJ -
CART peptide diurnal rhythm in brain and effect of fasting.
Brain Res Volume: 1032 Page(s): 111 - 115
01/25/2005 Authors: Vicentic A; Lakatos A; Hunter R; Philpot K; Dominguez G; Kuhar MJ -
Synthesis and ligand binding of tropane ring analogues of paroxetine (vol 41, pg 247, 2004)
JOURNAL OF MEDICINAL CHEMISTRY Volume: 48 Page(s): 336 - 336
01/13/2005 Authors: Keverline-Frantz KI; Boja JW; Kuhar MJ; Abraham P; Burgess JP; Lewin AH; Carroll FI -
Erratum: Synthesis and ligand binding of tropane ring analogues of paroxetine (Journal of Medical Chemistry (1998) 41 (247-257))
Journal of Medicinal Chemistry Volume: 48 Page(s): 336
01/13/2005 Authors: Keverline-Frantz KI; Boja JW; Kuhar MJ; Abraham P; Burgess JP; Lewin AH; Carroll FI -
A cocaine-and-amphetamine-regulated-transcript peptide projection from the lateral hypothalamus to the ventral tegmental area.
Neuroscience Volume: 135 Page(s): 915 - 925
01/01/2005 Authors: Philpot KB; Dallvechia-Adams S; Smith Y; Kuhar MJ -
Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide.
Neuroendocrinology Volume: 81 Page(s): 273 - 282
01/01/2005 Authors: Osei-Hyiaman D; Depetrillo M; Harvey-White J; Bannon AW; Cravatt BF; Kuhar MJ; Mackie K; Palkovits M; Kunos G -
Monoamine transporter binding, locomotor activity, and drug discrimination properties of 3-(4-substituted-phenyl)tropane-2-carboxylic acid methyl ester isomers.
J Med Chem Volume: 47 Page(s): 6401 - 6409
12/02/2004 Authors: Carroll FI; Runyon SP; Abraham P; Navarro H; Kuhar MJ; Pollard GT; Howard JL -
CART peptide levels are altered by a mutation associated with obesity at codon 34.
Mol Psychiatry Volume: 9 Page(s): 1065 - 1066
12/01/2004 Authors: Dominguez G; del Giudice EM; Kuhar MJ -
CART in feeding and obesity.
Trends Endocrinol Metab Volume: 15 Page(s): 454 - 459
11/01/2004 Authors: Hunter RG; Philpot K; Vicentic A; Dominguez G; Hubert GW; Kuhar MJ -
CART in feeding and obesity
TRENDS IN ENDOCRINOLOGY AND METABOLISM Volume: 15 Page(s): 454 - 459
11/01/2004 Authors: Hunter RG; Philpot K; Vicentic A; Dominguez G; Hubert GW; Kuhar MJ -
Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice.
Brain Res Volume: 1024 Page(s): 146 - 149
10/22/2004 Authors: Damaj MI; Hunter RG; Martin BR; Kuhar MJ -
CART peptides: modulators of mesolimbic dopamine, feeding, and stress.
Ann N Y Acad Sci Volume: 1025 Page(s): 363 - 369
10/01/2004 Authors: Dominguez G; Vicentic A; Del Giudice EM; Jaworski J; Hunter RG; Kuhar MJ -
CART peptide: central mediator of leptin-induced adipose tissue apoptosis?
Regul Pept Volume: 121 Page(s): 155 - 162
09/15/2004 Authors: Choi Y-H; Della-Fera MA; Li C; Hartzell DL; Little DE; Kuhar MJ; Baile CA -
Cocaine- and amphetamine-regulated transcript peptide levels in blood exhibit a diurnal rhythm: regulation by glucocorticoids.
Endocrinology Volume: 145 Page(s): 4119 - 4124
09/01/2004 Authors: Vicentic A; Dominguez G; Hunter RG; Philpot K; Wilson M; Kuhar MJ -
Transcriptional regulation of the CART promoter in CATH.a cells.
Brain Res Mol Brain Res Volume: 126 Page(s): 22 - 29
07/05/2004 Authors: Dominguez G; Kuhar MJ -
Differential CART mRNA expression between prairie and meadow voles: A role in pair-bonding?
Volume: 46 Page(s): 99 - 99
06/01/2004 Authors: Philpot KB; Hunter RG; Lim MM; Young LJ; Kuhar MJ -
Cocaine- and amphetamine-regulated transcript peptide in the rat anterior pituitary gland is localized in gonadotrophs and suppresses prolactin secretion.
Endocrinology Volume: 145 Page(s): 2542 - 2550
05/01/2004 Authors: Kuriyama G; Takekoshi S; Tojo K; Nakai Y; Kuhar MJ; Osamura RY -
CART mRNA in the rat nucleus accumbens is down-regulated via D3 dopamine receptors
Volume: 18 Page(s): A209 - A209
03/23/2004 Authors: Hunter RG; Kuhar MJ -
CART peptide levels in the brain exhibit a diurnal rhythm and are influenced by fasting
Volume: 18 Page(s): A574 - A574
03/23/2004 Authors: Vicentic A; Hunter R; Philpot K; Dominguez G; Kuhar M -
Cocaine- and amphetamine-regulated transcript (CART) is expressed in several islet cell types during rat development.
J Histochem Cytochem Volume: 52 Page(s): 169 - 177
02/01/2004 Authors: Wierup N; Kuhar M; Nilsson BO; Mulder H; Ekblad E; Sundler F -
Synthesis, monoamine transporter binding properties, and behavioral pharmacology of a series of 3beta-(substituted phenyl)-2beta-(3'-substituted isoxazol-5-yl)tropanes.
J Med Chem Volume: 47 Page(s): 296 - 302
01/15/2004 Authors: Carroll FI; Pawlush N; Kuhar MJ; Pollard GT; Howard JL -
Intra-accumbal injection of CART (cocaine-amphetamine regulated transcript) peptide reduces cocaine-induced locomotor activity.
J Pharmacol Exp Ther Volume: 307 Page(s): 1038 - 1044
12/01/2003 Authors: Jaworski JN; Kozel MA; Philpot KB; Kuhar MJ -
33rd Annual Meeting of the Society for Neuroscience
Volume: 28 Page(s): 799 - 801
12/01/2003 Authors: Sherritze S; Griffin S; Lemere C; Sigurdsson E; Hara H; Morgan T; Kuhar M; King S; Smith R; Alkadhi K -
Effects of adrenalectomy on CART expression in the rat arcuate nucleus.
Synapse Volume: 50 Page(s): 14 - 19
10/01/2003 Authors: Balkan B; Koylu E; Pogun S; Kuhar MJ -
Cocaine- and amphetamine-regulated transcript: distribution and function in rat gastrointestinal tract.
Neurogastroenterol Motil Volume: 15 Page(s): 545 - 557
10/01/2003 Authors: Ekblad E; Kuhar M; Wierup N; Sundler F -
Antinociceptive effects of supraspinal rat cart (55-102) peptide in mice.
Brain Res Volume: 983 Page(s): 233 - 236
09/05/2003 Authors: Damaj MI; Martin BR; Kuhar MJ -
Is the onset of psychoactive drug effects compatible with a protein-synthesis mechanism?
Neuropsychopharmacology Volume: 28 Suppl 1 Page(s): S94 - S97
07/01/2003 Authors: Kuhar MJ; Joyce AR -
CART peptides are modulators of mesolimbic dopamine and psychostimulants.
Life Sci Volume: 73 Page(s): 741 - 747
06/27/2003 Authors: Jaworski JN; Vicentic A; Hunter RG; Kimmel HL; Kuhar MJ -
CART peptides as targets for CNS drug development.
Curr Drug Targets CNS Neurol Disord Volume: 2 Page(s): 201 - 205
06/01/2003 Authors: Hunter RG; Kuhar MJ -
CART peptides in drug abuse and dependence
Volume: 13 Page(s): S20 - S21
03/01/2003 Authors: Hunter RG; Jaworski JN; Dominguez G; Kuhar MJ -
Withdrawal from repeated cocaine alters dopamine transporter protein turnover in the rat striatum.
J Pharmacol Exp Ther Volume: 304 Page(s): 15 - 21
01/01/2003 Authors: Kimmel HL; Carroll FI; Kuhar MJ -
Introduction
Neuropsychopharmacology Volume: 28 Page(s): S1
01/01/2003 Authors: Kuhar MJ; Pogun S -
Synthesis and transporter binding properties of 3beta-[4'-(phenylalkyl, -phenylalkenyl, and -phenylalkynyl)phenyl]tropane-2beta-carboxylic acid methyl esters: evidence of a remote phenyl binding domain on the dopamine transporter.
J Med Chem Volume: 45 Page(s): 4029 - 4037
08/29/2002 Authors: Blough BE; Keverline KI; Nie Z; Navarro H; Kuhar MJ; Carroll FI -
Synthesis and pharmacology of potential site specific cocaine abuse treatment agents: Exploration of a secondary phenyl group interaction at the dopamine transporter.
Volume: 224 Page(s): U52 - U52
08/18/2002 Authors: Coons S; Javanmard S; Deutsch HM; Collard DM; Schweri MM; Kuhar MJ -
CART promoter CRE site binds phosphorylated CREB.
Brain Res Mol Brain Res Volume: 104 Page(s): 81 - 85
07/15/2002 Authors: Lakatos A; Dominguez G; Kuhar MJ -
Cocaine- and amphetamine-regulated transcript peptide projections in the ventral midbrain: colocalization with gamma-aminobutyric acid, melanin-concentrating hormone, dynorphin, and synaptic interactions with dopamine neurons.
J Comp Neurol Volume: 448 Page(s): 360 - 372
07/08/2002 Authors: Dallvechia-Adams S; Kuhar MJ; Smith Y -
Synthesis and pharmacology of site specific cocaine abuse treatment agents: 5-and 6-substituted trans-2-aminomethyl-3-(4-chloro)-phenylbicyclo[2.2.2]octanes and 2-amino-3-(4-chloro)-phenylbicyclo[2.2.2]octanes.
Volume: 223 Page(s): A96 - A96
04/07/2002 Authors: Javanmard S; Deutsch HM; Collard DM; Kuhar MJ; Schweri MM -
Characterization of the cocaine- and amphetamine-regulated transcript (CART) peptide gene promoter and its activation by a cyclic AMP-dependent signaling pathway in GH3 cells.
J Neurochem Volume: 80 Page(s): 885 - 893
03/01/2002 Authors: Dominguez G; Lakatos A; Kuhar MJ -
Activity of various CART peptides in changing locomotor activity in the rat.
Neuropeptides Volume: 36 Page(s): 9 - 12
02/01/2002 Authors: Kimmel HL; Thim L; Kuhar MJ -
CART peptides.
Neuropeptides Volume: 36 Page(s): 1 - 8
02/01/2002 Authors: Kuhar MJ; Adams S; Dominguez G; Jaworski J; Balkan B -
Social rank and vulnerability to drug abuse.
Nat Neurosci Volume: 5 Page(s): 88 - 90
02/01/2002 Authors: Kuhar MJ -
Activity changing of various CART peptides in locomotor activity in the rat
NEUROPEPTIDES Volume: 36 Page(s): 9 - 12
02/01/2002 Authors: Kimmel HL; Thim L; Kuhar MJ -
Synthesis and pharmacology of potential site-specific cocaine abuse treatment agents: The role of the phenyl group in 2-substituted-6-aminobicyclo[2.2.2]Octanes
Medicinal Chemistry Research Volume: 11 Page(s): 24 - 38
01/01/2002 Authors: Coons S; Javanmard S; Collard DM; Kuhar MJ; Schweri MM; Deutsch HM -
Locomotor stimulant effects of novel phenyltropanes in the mouse.
Drug Alcohol Depend Volume: 65 Page(s): 25 - 36
12/01/2001 Authors: Kimmel HL; Carroll FI; Kuhar MJ -
The effect of adrenalectomy on cocaine and amphetamine-regulated transcript (CART) expression in the hypothalamic nuclei of the rat.
Brain Res Volume: 917 Page(s): 15 - 20
10/26/2001 Authors: Balkan B; Koylu EO; Kuhar MJ; Pogun S -
Slow onset of CNS drugs: can changes in protein concentration account for the delay?
Trends Pharmacol Sci Volume: 22 Page(s): 450 - 456
09/01/2001 Authors: Kuhar MJ; Joyce AR -
[(125)I]3beta-(4-ethyl-3-iodophenyl)nortropane-2beta-carboxylic acid methyl ester ([(125)I]EINT): a potent and selective radioligand for the brain serotonin transporter.
Synapse Volume: 41 Page(s): 241 - 247
09/01/2001 Authors: Navarro HA; Xu H; Zhong D; Blough BE; Ross WP; Kuhar MJ; Carroll FI -
Preferential increases in nucleus accumbens dopamine after systemic cocaine administration are caused by unique characteristics of dopamine neurotransmission.
J Neurosci Volume: 21 Page(s): 6338 - 6347
08/15/2001 Authors: Wu Q; Reith ME; Kuhar MJ; Carroll FI; Garris PA -
Anticocaine catalytic antibodies have no affinity for RTI compounds: implications for treatment.
Synapse Volume: 41 Page(s): 176 - 178
08/01/2001 Authors: Kuhar MJ; Carroll FI; Bharat N; Landry DW -
Dopamine D1 and D2 receptors influence dopamine transporter synthesis and degradation in the rat.
J Pharmacol Exp Ther Volume: 298 Page(s): 129 - 140
07/01/2001 Authors: Kimmel HL; Joyce AR; Carroll FI; Kuhar MJ -
Intracerebroventricular CART peptide reduces rat ingestive behavior and alters licking microstructure.
Am J Physiol Regul Integr Comp Physiol Volume: 280 Page(s): R1613 - R1619
06/01/2001 Authors: Aja S; Schwartz GJ; Kuhar MJ; Moran TH -
CART peptide-immunoreactive projection from the nucleus accumbens targets substantia nigra pars reticulata neurons in the rat.
J Comp Neurol Volume: 434 Page(s): 29 - 39
05/21/2001 Authors: Dallvechia-Adams S; Smith Y; Kuhar MJ -
Regenerating optic fibers correct large-scale errors by random growth: evidence from in vivo imaging.
J Comp Neurol Volume: 434 Page(s): 40 - 55
05/21/2001 Authors: Dawson AJ; Meyer RL -
In vitro autoradiography.
Curr Protoc Pharmacol Volume: Chapter 8 Page(s): Unit - 8.1
05/01/2001 Authors: Kuhar MJ -
Genes in drug abuse.
Drug Alcohol Depend Volume: 62 Page(s): 157 - 162
05/01/2001 Authors: Kuhar MJ; Joyce A; Dominguez G -
Neurotransmitter transporters synthesis and degradation rates.
Life Sci Volume: 68 Page(s): 2181 - 2185
04/06/2001 Authors: Kimmel H; Vicentic A; Kuhar MJ -
RTI-76, an irreversible inhibitor of dopamine transporter binding, increases locomotor activity in the rat at high doses.
Brain Res Volume: 897 Page(s): 157 - 163
04/06/2001 Authors: Kimmel HL; Carroll FI; Kuhar MJ -
Characterization of CART neurons in the rat and human hypothalamus.
J Comp Neurol Volume: 432 Page(s): 1 - 19
03/26/2001 Authors: Elias CF; Lee CE; Kelly JF; Ahima RS; Kuhar M; Saper CB; Elmquist JK -
Actions of cocaine- and amphetamine-regulated transcript (CART) peptide on regulation of appetite and hypothalamo-pituitary axes in vitro and in vivo in male rats.
Brain Res Volume: 893 Page(s): 186 - 194
03/02/2001 Authors: Stanley SA; Small CJ; Murphy KG; Rayes E; Abbott CR; Seal LJ; Morgan DG; Sunter D; Dakin CL; Kim MS -
Intracerebroventricular CART peptide reduces rat ingestive behavior and alters licking microstructure
American Journal of Physiology - Regulatory Integrative and Comparative Physiology Volume: 280
01/01/2001 Authors: Aja S; Schwartz GJ; Kuhar MJ; Moran TH -
Erratum: Intracerebroventricular CART peptide reduces rat ingestive behavior and alters licking microstructure (American Journal of Physiology - Regulatory, Integrative and parative Physiology (2001) (R1613-R1619))
American Journal of Physiology - Regulatory Integrative and Comparative Physiology Volume: 281
01/01/2001 Authors: Aja S; Schwartz GJ; Kuhar MJ; Moran TH -
Association of cocaine- and amphetamine-regulated transcript-immunoreactive elements with thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and its role in the regulation of the hypothalamic-pituitary-thyroid axis during fasting.
J Neurosci Volume: 20 Page(s): 9224 - 9234
12/15/2000 Authors: Fekete C; Mihly E; Luo LG; Kelly J; Clausen JT; Mao Q; Rand WM; Moss LG; Kuhar M; Emerson CH -
Hypothalamic CART and serum leptin levels are reduced in the anorectic (anx/anx) mouse.
Brain Res Mol Brain Res Volume: 84 Page(s): 97 - 105
12/08/2000 Authors: Johansen JE; Broberger C; Lavebratt C; Johansson C; Kuhar MJ; Hkfelt T; Schalling M -
3alpha-(4-Substituted phenyl)nortropane-2beta-carboxylic acid methyl esters show selective binding at the norepinephrine transporter.
Bioorg Med Chem Lett Volume: 10 Page(s): 2445 - 2447
11/06/2000 Authors: Blough BE; Holmquist CR; Abraham P; Kuhar MJ; Carroll FI -
RTI-76, an isothiocyanate derivative of a phenyltropane cocaine analog, as a tool for irreversibly inactivating dopamine transporter function in vitro.
Naunyn Schmiedebergs Arch Pharmacol Volume: 362 Page(s): 238 - 247
09/01/2000 Authors: Wang LC; Berfield JL; Kuhar MJ; Carroll FI; Reith ME -
Quantification and synthesis of cocaine- and amphetamine-regulated transcript peptide (79-102)-like immunoreactivity and mRNA in rat tissues.
J Endocrinol Volume: 166 Page(s): 659 - 668
09/01/2000 Authors: Murphy KG; Abbott CR; Mahmoudi M; Hunter R; Gardiner JV; Rossi M; Stanley SA; Ghatei MA; Kuhar MJ; Bloom SR -
Intra-ventral tegmental area injection of rat cocaine and amphetamine-regulated transcript peptide 55-102 induces locomotor activity and promotes conditioned place preference.
J Pharmacol Exp Ther Volume: 294 Page(s): 784 - 792
08/01/2000 Authors: Kimmel HL; Gong W; Vechia SD; Hunter RG; Kuhar MJ -
Co-localization of cart peptide immunoreactivity and nitric oxide synthase activity in rat hypothalamus.
Brain Res Volume: 868 Page(s): 352 - 357
06/23/2000 Authors: Koylu EO; Weruaga E; Balkan B; Alonso JR; Kuhar MJ; Pogun S -
CART peptides.
Regul Pept Volume: 89 Page(s): 1 - 6
05/10/2000 Authors: Kuhar MJ; Adams LD; Hunter RG; Vechia SD; Smith Y -
Dopamine transporter synthesis and degradation rate in rat striatum and nucleus accumbens using RTI-76.
Neuropharmacology Volume: 39 Page(s): 578 - 585
02/14/2000 Authors: Kimmel HL; Carroll FI; Kuhar MJ -
Comparative behavioral pharmacology of cocaine and the selective dopamine uptake inhibitor RTI-113 in the squirrel monkey.
J Pharmacol Exp Ther Volume: 292 Page(s): 521 - 529
02/01/2000 Authors: Howell LL; Czoty PW; Kuhar MJ; Carrol FI -
CART peptide immunoreactivity in the hypothalamus and pituitary in monkeys: analysis of ultrastructural features and synaptic connections in the paraventricular nucleus.
J Comp Neurol Volume: 416 Page(s): 291 - 308
01/17/2000 Authors: Dall Vechia S; Lambert PD; Couceyro PC; Kuhar MJ; Smith Y -
Synthesis of [125I]-3-(4-Ethyl-3-iodophenyl)nortropane-2-carboxylic acid methyl ester (125I]EINT)
Journal of Labelled Compounds and Radiopharmaceuticals Volume: 43 Page(s): 137 - 146
01/01/2000 Authors: Zhong D; Blough BE; Kuhar MJ; Carroll FI -
CART: from gene to function.
Brain Res Volume: 848 Page(s): 137 - 140
11/27/1999 Authors: Adams LD; Gong W; Vechia SD; Hunter RG; Kuhar MJ -
CART peptides and feeding
Volume: 848 Page(s): A19 - A19
11/27/1999 Authors: Kuhar MJ; Gong W; Adams L; Dall Vechia S; Hunter R; Elmquist J -
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-substituted-6-amino-5-phenylbicyclo[2.2.2]octanes.
J Med Chem Volume: 42 Page(s): 4836 - 4843
11/18/1999 Authors: Javanmard S; Deutsch HM; Collard DM; Kuhar MJ; Schweri MM -
Cocaine- and amphetamine-regulated transcript in the rat vagus nerve: A putative mediator of cholecystokinin-induced satiety.
Proc Natl Acad Sci U S A Volume: 96 Page(s): 13506 - 13511
11/09/1999 Authors: Broberger C; Holmberg K; Kuhar MJ; Hkfelt T -
Neuropeptide Y innervation and neuropeptide-Y-Y1-receptor-expressing neurons in the paraventricular hypothalamic nucleus of the mouse.
Neuroendocrinology Volume: 70 Page(s): 295 - 305
11/01/1999 Authors: Broberger C; Visser TJ; Kuhar MJ; Hkfelt T -
Serotonin transporter production and degradation rates: studies with RTI-76.
Brain Res Volume: 841 Page(s): 1 - 10
09/11/1999 Authors: Vicentic A; Battaglia G; Carroll FI; Kuhar MJ -
CART peptide analysis by Western blotting.
Synapse Volume: 33 Page(s): 163 - 171
09/01/1999 Authors: Kuhar MJ; Yoho LL -
2-substituted-6-amino-5-phenyl bicyclo[2.2.2]octanes as monoamine uptake inhibitors.
Volume: 218 Page(s): U975 - U975
08/22/1999 Authors: Deutsch HM; Collard DM; Javanmard S; Holtzman SG; Spealman RD; Kuhar MJ; Schweri MM -
Studies of selected phenyltropanes at monoamine transporters.
Drug Alcohol Depend Volume: 56 Page(s): 9 - 15
08/02/1999 Authors: Kuhar MJ; McGirr KM; Hunter RG; Lambert PD; Garrett BE; Carroll FI -
Chronic lithium treatment decreases neuronal activity in the nucleus accumbens and cingulate cortex of the rat.
Neuropsychopharmacology Volume: 21 Page(s): 229 - 237
08/01/1999 Authors: Lambert PD; McGirr KM; Ely TD; Kilts CD; Kuhar MJ -
Pharmacotherapies for treatment of cocaine abuse: preclinical aspects.
J Med Chem Volume: 42 Page(s): 2721 - 2736
07/29/1999 Authors: Carroll FI; Howell LL; Kuhar MJ -
Cholinergic axon terminals in the ventral tegmental area target a subpopulation of neurons expressing low levels of the dopamine transporter.
J Comp Neurol Volume: 410 Page(s): 197 - 210
07/26/1999 Authors: Garzn M; Vaughan RA; Uhl GR; Kuhar MJ; Pickel VM -
CART peptides: novel addiction- and feeding-related neuropeptides.
Trends Neurosci Volume: 22 Page(s): 316 - 320
07/01/1999 Authors: Kuhar MJ; Dall Vechia SE -
CART peptide-immunoreactive neurones in the nucleus accumbens in monkeys: ultrastructural analysis, colocalization studies, and synaptic interactions with dopaminergic afferents.
J Comp Neurol Volume: 407 Page(s): 491 - 511
05/17/1999 Authors: Smith Y; Kieval J; Couceyro PR; Kuhar MJ -
Dopamine transporter changes in cocaine users following one month abstinence.
Volume: 40 Page(s): 109P - 109P
05/01/1999 Authors: Wong DF; Rothman RB; Contoreggi C; Yokoi F; Stephane M; Dogan S; Schretlen D; Kuhar M; Gjedde A -
CART peptides colocalize with tyrosine hydroxylase neurons in rat locus coeruleus.
Synapse Volume: 31 Page(s): 309 - 311
03/15/1999 Authors: Koylu EO; Smith Y; Couceyro PR; Kuhar MJ -
Comparative studies of epibatidine derivatives [18F]NFEP and [18F]N-methyl-NFEP: kinetics, nicotine effect, and toxicity.
Nucl Med Biol Volume: 26 Page(s): 139 - 148
01/01/1999 Authors: Ding YS; Molina PE; Fowler JS; Logan J; Volkow ND; Kuhar MJ; Carroll FI -
Synthesis of 3-(4-[125I]Iodophenyl)tropane-2-pyrrolidine carboxamide ([125I]RTI-229)
Journal of Labelled Compounds and Radiopharmaceuticals Volume: 42 Page(s): 281 - 286
01/01/1999 Authors: Zhong D; Kotian P; Wyrick CD; Seltzman HH; Kepler JA; Boja JW; Kuhar MJ; Carroll FI -
Synthesis and transporter binding properties of (R)-2 beta, 3 beta- and (R)-2 alpha, 3 alpha-diaryltropanes.
Bioorg Med Chem Lett Volume: 8 Page(s): 3689 - 3692
12/15/1998 Authors: Jiang S; Chang AC; Abraham P; Kuhar MJ; Carroll FI -
Leptin activates hypothalamic CART neurons projecting to the spinal cord.
Neuron Volume: 21 Page(s): 1375 - 1385
12/01/1998 Authors: Elias CF; Lee C; Kelly J; Aschkenasi C; Ahima RS; Couceyro PR; Kuhar MJ; Saper CB; Elmquist JK -
RTI-113 administration reduces cocaine self-administration at high occupancy of dopamine transporter.
Synapse Volume: 30 Page(s): 49 - 55
09/01/1998 Authors: Dworkin SI; Lambert P; Sizemore GM; Carroll FI; Kuhar MJ -
Multiple binding sites for [125I]RTI-121 and other cocaine analogs in rat frontal cerebral cortex.
Synapse Volume: 30 Page(s): 9 - 17
09/01/1998 Authors: Boja JW; Carroll FI; Vaughan RA; Kopajtic T; Kuhar MJ -
Cocaine- and amphetamine-regulated transcript (CART) peptide immunoreactivity in myenteric plexus neurons of the rat ileum and co-localization with choline acetyltransferase.
Synapse Volume: 30 Page(s): 1 - 8
09/01/1998 Authors: Couceyro P; Paquet M; Koylu E; Kuhar MJ; Smith Y -
CART peptides in the central control of feeding and interactions with neuropeptide Y.
Synapse Volume: 29 Page(s): 293 - 298
08/01/1998 Authors: Lambert PD; Couceyro PR; McGirr KM; Dall Vechia SE; Smith Y; Kuhar MJ -
Pathways of addiction: Opportunities in drug abuse research.
JOURNAL OF NERVOUS AND MENTAL DISEASE Volume: 186 Page(s): 511 - 512
08/01/1998 Authors: Kuhar MJ -
Dopamine D-2 receptor-mediated regulation of central cholinergic activity: PET studies with [F-18]fluoroepibatidine.
Volume: 39 Page(s): 12P - 12P
05/01/1998 Authors: Ding YS; Fowler JS; Volkow ND; Logan J; Dewey SL; Carroll FI; Kuhar MJ -
Effect of dental adhesive coat on the permeability of the ground or acid-etched dental enamel.
Volume: 77 Page(s): 1231 - 1231
05/01/1998 Authors: Kuhar M; Cevc P; Funduk N -
Cocaine- and amphetamine-regulated transcript peptide immunohistochemical localization in the rat brain.
J Comp Neurol Volume: 391 Page(s): 115 - 132
02/02/1998 Authors: Koylu EO; Couceyro PR; Lambert PD; Kuhar MJ -
Parkinsonian patients report blunted subjective effects of methylphenidate.
Exp Clin Psychopharmacol Volume: 6 Page(s): 54 - 63
02/01/1998 Authors: Persico AM; Reich S; Henningfield JE; Kuhar MJ; Uhl GR -
Synthesis and ligand binding of tropane ring analogues of paroxetine.
J Med Chem Volume: 41 Page(s): 247 - 257
01/15/1998 Authors: Keverline-Frantz KI; Boja JW; Kuhar MJ; Abraham P; Burgess JP; Lewin AH; Carroll FI -
Recent biochemical studies of the dopamine transporter--a CNS drug target.
Life Sci Volume: 62 Page(s): 1573 - 1575
01/01/1998 Authors: Kuhar MJ -
Phosphorylation of dopamine transporters and rapid adaptation to cocaine.
Adv Pharmacol Volume: 42 Page(s): 1042 - 1045
01/01/1998 Authors: Vaughan RA; Huff RA; Uhl GR; Kuhar MJ -
Localization of dopamine transporter protein by microscopic histochemistry.
Adv Pharmacol Volume: 42 Page(s): 168 - 170
01/01/1998 Authors: Kuhar MJ; Vaughan R; Uhl G; Cerruti C; Revay R; Freed C; Nirenburg M; Pickel V -
3 beta-phenyl-2 beta-substituted tropanes - An SAR analysis
MEDICINAL CHEMISTRY RESEARCH Volume: 8 Page(s): 59 - 65
01/01/1998 Authors: Carroll FI; Lewin AH; Kuhar MJ -
Positional isomers and analogs of mazindol as potential inhibitors of the cocaine binding site on the dopamine transporter site
Medicinal Chemistry Research Volume: 8 Page(s): 77 - 90
01/01/1998 Authors: Houlihan WJ; Boja JW; Kopajtic TA; Kuhar MJ; Degrado SJ; Toledo L -
3-Phenyl-2-substituted tropanes - An SAR analysis
Medicinal Chemistry Research Volume: 8 Page(s): 59 - 65
01/01/1998 Authors: Carroll FI; Lewin AH; Kuhar MJ -
Dopamine transporter changes in neuropsychiatric disorders.
Adv Pharmacol Volume: 42 Page(s): 219 - 223
01/01/1998 Authors: Wong DF; Ricaurte G; Grnder G; Rothman R; Naidu S; Singer H; Harris J; Yokoi F; Villemagne V; Szymanski S -
3 Beta-(4-ethyl-3-iodophenyl)nortropane-2 beta-carboxylic acid methyl ester as a high-affinity selective ligand for the serotonin transporter.
J Med Chem Volume: 40 Page(s): 3861 - 3864
11/21/1997 Authors: Blough BE; Abraham P; Mills AC; Lewin AH; Boja JW; Scheffel U; Kuhar MJ; Carroll FI -
Immunohistochemical localization of novel CART peptides in rat hypothalamus, pituitary and adrenal gland.
J Neuroendocrinol Volume: 9 Page(s): 823 - 833
11/01/1997 Authors: Koylu EO; Couceyro PR; Lambert PD; Ling NC; DeSouza EB; Kuhar MJ -
Fluoro-norchloroepibatidine: preclinical assessment of acute toxicity.
Nucl Med Biol Volume: 24 Page(s): 743 - 747
11/01/1997 Authors: Molina PE; Ding YS; Carroll FI; Liang F; Volkow ND; Pappas N; Kuhar M; Abumrad N; Gatley SJ; Fowler JS -
Synthesis of [F-18]norchlorofluoroepibatidine and its N-methyl derivative: New PET ligands for mapping nicotinic acetylcholine receptors
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS Volume: 39 Page(s): 827 - 832
10/01/1997 Authors: Ding YS; Liang F; Fowler JS; Kuhar MJ; Carroll FI -
The dopamine transporter: comparative ultrastructure of dopaminergic axons in limbic and motor compartments of the nucleus accumbens.
J Neurosci Volume: 17 Page(s): 6899 - 6907
09/15/1997 Authors: Nirenberg MJ; Chan J; Pohorille A; Vaughan RA; Uhl GR; Kuhar MJ; Pickel VM -
Ultrastructural localization of CART (cocaine- and amphetamine-regulated transcript) peptides in the nucleus accumbens of monkeys.
Synapse Volume: 27 Page(s): 90 - 94
09/01/1997 Authors: Smith Y; Koylu EO; Couceyro P; Kuhar MJ -
Cocaine self-administration alters brain NADH dehydrogenase mRNA levels.
Neuroreport Volume: 8 Page(s): 2437 - 2441
07/28/1997 Authors: Couceyro P; Shoaib M; McCoy M; Goldberg SR; Kuhar MJ -
Synthesis and nicotinic acetylcholine receptor binding properties of exo-2-(2'-fluoro-5'-pyridinyl)-7-azabicyclo-[2.2.1]heptane: a new positron emission tomography ligand for nicotinic receptors.
J Med Chem Volume: 40 Page(s): 2293 - 2295
07/18/1997 Authors: Liang F; Navarro HA; Abraham P; Kotian P; Ding YS; Fowler J; Volkow N; Kuhar MJ; Carroll FI -
Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area.
J Neurosci Volume: 17 Page(s): 5255 - 5262
07/15/1997 Authors: Nirenberg MJ; Chan J; Vaughan RA; Uhl GR; Kuhar MJ; Pickel VM -
Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes.
J Biol Chem Volume: 272 Page(s): 15541 - 15546
06/13/1997 Authors: Vaughan RA; Huff RA; Uhl GR; Kuhar MJ -
Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area.
J Neurosci Volume: 17 Page(s): 4037 - 4044
06/01/1997 Authors: Nirenberg MJ; Chan J; Vaughan RA; Uhl GR; Kuhar MJ; Pickel VM -
Further studies on the anatomical distribution of CART by in situ hybridization.
J Chem Neuroanat Volume: 12 Page(s): 229 - 241
05/01/1997 Authors: Couceyro PR; Koylu EO; Kuhar MJ -
PET studies of [18F]norchlorofluoroepibatidine in mapping nicotinic acetylcholine receptors (nAChR).
Volume: 38 Page(s): 295 - 295
05/01/1997 Authors: Ding YS; Fowler JS; Gatley SJ; Volkow ND; Logan J; Dewey SL; Liang F; Carroll FI; Kuhar MJ -
Dopamine transporter occupancy by RTI-55, inhibition of dopamine transport and stimulation of locomotor activity
Volume: 38 Page(s): 222 - 222
05/01/1997 Authors: Gatley SJ; Gifford AN; Volkow ND; Fowler JS; Kuhar MJ; Carroll FI -
[F-18]norchlorofluorepibatidine (NFED): Preclinical toxicological studies.
Volume: 38 Page(s): 1209 - 1209
05/01/1997 Authors: Molina P; Ding YS; Carroll FI; Liang F; Volkow N; Kuhar M; Pappas N; King P; Abumrad N; Fowler JS -
Antihistamine responsive cluster headache in a teenaged girl.
Headache Volume: 37 Page(s): 296 - 298
05/01/1997 Authors: Neubauer D; Kuhar M; Ravnik IM -
3 alpha-(substituted phenyl)tropane-2 beta-carboxylic acid esters: Ligands with unexpectedly high affinity and selectivity at the dopamine transporter.
Volume: 213 Page(s): 191 - MEDI
04/13/1997 Authors: Holmquist CR; KeverlineFrantz KI; Abraham P; Boja JW; Kuhar MJ; Carroll FI -
Synthesis and transporter binding properties of 2,3-diphenyltropane stereoisomers. Comparison to 3beta-phenyltropane-2beta-carboxylic acid esters.
J Med Chem Volume: 40 Page(s): 1247 - 1251
04/11/1997 Authors: Chang AC; Burgess JP; Mascarella SW; Abraham P; Kuhar MJ; Carroll FI -
RTI-352: a 3 alpha analogue of RTI-55 as an in vivo dopamine transporter binding ligand.
Synapse Volume: 25 Page(s): 389 - 392
04/01/1997 Authors: Zhan Y; Saindane AM; Scheffel U; Carroll FI; Holmquist CR; Kepler JA; Taylor GF; Kuhar MJ -
N-substituted phenyltropanes as in vivo binding ligands for rapid imaging studies of the dopamine transporter.
Synapse Volume: 25 Page(s): 345 - 349
04/01/1997 Authors: Scheffel U; Lever JR; Abraham P; Parham KR; Mathews WB; Kopajtic T; Carroll FI; Kuhar MJ -
Quantification of neuroreceptors in the living human brain: IV. Effect of aging and elevations of D2-like receptors in schizophrenia and bipolar illness.
J Cereb Blood Flow Metab Volume: 17 Page(s): 331 - 342
03/01/1997 Authors: Wong DF; Pearlson GD; Tune LE; Young LT; Meltzer CC; Dannals RF; Ravert HT; Reith J; Kuhar MJ; Gjedde A -
Phorbol esters increase dopamine transporter phosphorylation and decrease transport Vmax.
J Neurochem Volume: 68 Page(s): 225 - 232
01/01/1997 Authors: Huff RA; Vaughan RA; Kuhar MJ; Uhl GR -
Cocaine and the dopamine transporter
Page(s): 207 - 212
01/01/1997 Authors: Kuhar MJ -
Synthesis of the isomers of (1R)-3-(phenylthio)tropane-2-carboxylic acid methyl ester. A new class of ligands for the dopamine transporter
Chemical Communications Page(s): 555 - 556
01/01/1997 Authors: Thiruvazhi M; Abraham P; Kuhar MJ; Carroll FI -
Phosphorylation of Dopamine Transporters and Rapid Adaptation to Cocaine
Advances in Pharmacology Volume: 42 Page(s): 1042 - 1045
01/01/1997 Authors: Vaughan RA; Huff RA; Uhl GR; Kuhar MJ -
Localization of Dopamine Transporter Protein by Microscopic Histochemistry
Advances in Pharmacology Volume: 42 Page(s): 168 - 170
01/01/1997 Authors: Kuhar MJ; Vaughan R; Uhl G; Cerruti C; Revay R; Freed C; Nirenburg M; Pickel V -
Synthesis of [18F]norchlorofluoroepibatidine and its N-methyl derivative: New PET ligands for mapping nicotinic acetylcholine receptors
Journal of Labelled Compounds and Radiopharmaceuticals Volume: 39 Page(s): 827 - 832
01/01/1997 Authors: Ding YS; Liang F; Fowler JS; Kuhar MJ; Carroll FI -
Halogenated mazindol analogs as potential inhibitors of the cocaine binding site at the dopamine transporter.
J Med Chem Volume: 39 Page(s): 4935 - 4941
12/06/1996 Authors: Houlihan WJ; Boja JW; Parrino VA; Kopajtic TA; Kuhar MJ -
Mapping nicotinic acetylcholine receptors with PET.
Synapse Volume: 24 Page(s): 403 - 407
12/01/1996 Authors: Ding YS; Gatley SJ; Fowler JS; Volkow ND; Aggarwal D; Logan J; Dewey SL; Liang F; Carroll FI; Kuhar MJ -
Phosphorylation of dopamine transporters in rat striatum
FASEB Journal Volume: 10
12/01/1996 Authors: Vaughan R; Huff R; Uhl G; Kuhar M -
European standard proposal for geographic data position
Geodetski Vestnik (Ljubljana) Volume: 40 Page(s): 343 - 348
12/01/1996 Authors: Ferlan M; Kuhar M; Sumrada R -
3 alpha-(4'-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters: novel ligands with high affinity and selectivity at the dopamine transporter.
J Med Chem Volume: 39 Page(s): 4139 - 4141
10/11/1996 Authors: Holmquist CR; Keverline-Frantz KI; Abraham P; Boja JW; Kuhar MJ; Carroll FI -
Recovery of dopamine transporter binding and function after intrastriatal administration of the irreversible inhibitor RTI-76 [3 beta-(3p-chlorophenyl) tropan-2 beta-carboxylic acid p-isothiocyanatophenylethyl ester hydrochloride].
J Pharmacol Exp Ther Volume: 279 Page(s): 200 - 206
10/01/1996 Authors: Fleckenstein AE; Pgn S; Carroll FI; Kuhar MJ -
Synthesis and transporter binding properties of 3 beta-(4'-alkyl-, 4'-alkenyl-, and 4'-alkynylphenyl)nortropane-2 beta-carboxylic acid methyl esters: serotonin transporter selective analogs.
J Med Chem Volume: 39 Page(s): 4027 - 4035
09/27/1996 Authors: Blough BE; Abraham P; Lewin AH; Kuhar MJ; Boja JW; Carroll FI -
Highly potent cocaine analogs cause long-lasting increases in locomotor activity.
Eur J Pharmacol Volume: 311 Page(s): 109 - 114
09/12/1996 Authors: Fleckenstein AE; Kopajtic TA; Boja JW; Carroll FI; Kuhar MJ -
Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis.
J Biol Chem Volume: 271 Page(s): 21672 - 21680
08/30/1996 Authors: Vaughan RA; Kuhar MJ -
Synthesis, ligand binding, and quantitative structure-activity relationship study of 3 beta-(4'-substituted phenyl)-2 beta-heterocyclic tropanes: evidence for an electrostatic interaction at the 2 beta-position.
J Med Chem Volume: 39 Page(s): 2753 - 2763
07/05/1996 Authors: Kotian P; Mascarella SW; Abraham P; Lewin AH; Boja JW; Kuhar MJ; Carroll FI -
Neurochemical changes in cocaine withdrawal.
Trends Pharmacol Sci Volume: 17 Page(s): 260 - 264
07/01/1996 Authors: Kuhar MJ; Pilotte NS -
Effect of dopaminergic drugs on the in vivo binding of [3H]WIN 35,428 to central dopamine transporters.
Synapse Volume: 23 Page(s): 61 - 69
06/01/1996 Authors: Scheffel U; Steinert C; Kim SE; Ehlers MD; Boja JW; Kuhar MJ -
Dopamine transporters are markedly reduced in Lesch-Nyhan disease in vivo.
Proc Natl Acad Sci U S A Volume: 93 Page(s): 5539 - 5543
05/28/1996 Authors: Wong DF; Harris JC; Naidu S; Yokoi F; Marenco S; Dannals RF; Ravert HT; Yaster M; Evans A; Rousset O -
Species- and brain region-specific dopamine transporters: immunological and glycosylation characteristics.
J Neurochem Volume: 66 Page(s): 2146 - 2152
05/01/1996 Authors: Vaughan RA; Brown VL; McCoy MT; Kuhar MJ -
Evaluation of [11C]RTI-121 as a selective radioligand for PET studies of the dopamine transporter.
Nucl Med Biol Volume: 23 Page(s): 377 - 384
04/01/1996 Authors: Hume SP; Luthra SK; Brown DJ; Opacka-Juffry J; Osman S; Ashworth S; Myers R; Brady F; Carroll FI; Kuhar MJ -
Synthesis and in vivo studies of a selective ligand for the dopamine transporter: 3 beta-(4-[125I]iodophenyl) tropan-2 beta-carboxylic acid isopropyl ester ([125I]RTI-121).
Nucl Med Biol Volume: 23 Page(s): 277 - 284
04/01/1996 Authors: Lever JR; Scheffel U; Stathis M; Seltzman HH; Wyrick CD; Abraham P; Parham K; Thomas BF; Boja JW; Kuhar MJ -
Dopamine transporter immunohistochemistry in median eminence, amygdala, and other areas of the rat brain.
Synapse Volume: 22 Page(s): 93 - 99
02/01/1996 Authors: Revay R; Vaughan R; Grant S; Kuhar MJ -
Dopamine transporter immunohistochemistry in median eminence, amygdala, and other areas of the rat brain
SYNAPSE Volume: 22 Page(s): 93 - 99
02/01/1996 Authors: Revay R; Vaughan R; Grant S; Kuhar MJ -
Displacement of RTI-55 from the dopamine transporter by cocaine.
Eur J Pharmacol Volume: 296 Page(s): 145 - 151
01/25/1996 Authors: Gatley SJ; Volkow ND; Chen R; Fowler JS; Carroll FI; Kuhar MJ -
The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons.
J Neurosci Volume: 16 Page(s): 436 - 447
01/15/1996 Authors: Nirenberg MJ; Vaughan RA; Uhl GR; Kuhar MJ; Pickel VM -
Cocaine withdrawal reduces dopamine transporter binding in the shell of the nucleus accumbens.
Synapse Volume: 22 Page(s): 87 - 92
01/01/1996 Authors: Pilotte NS; Sharpe LG; Rountree SD; Kuhar MJ -
In vivo labeling of neuronal nicotinic acetylcholine receptors with radiolabeled isomers of norchloroepibatidine.
Neuroreport Volume: 6 Page(s): 2483 - 2488
12/15/1995 Authors: Scheffel U; Taylor GF; Kepler JA; Carroll FI; Kuhar MJ -
Development of imaging agents for the dopamine transporter.
Med Res Rev Volume: 15 Page(s): 419 - 444
09/01/1995 Authors: Carroll FI; Scheffel U; Dannals RF; Boja JW; Kuhar MJ -
Synthesis and ligand binding study of 3 beta-(4'-substituted phenyl)-2 beta-(heterocyclic)tropanes.
J Med Chem Volume: 38 Page(s): 3451 - 3453
09/01/1995 Authors: Kotian P; Abraham P; Lewin AH; Mascarella SW; Boja JW; Kuhar MJ; Carroll FI -
Dopamine transporter immunoreactivity in rat brain.
J Comp Neurol Volume: 359 Page(s): 340 - 349
08/21/1995 Authors: Freed C; Revay R; Vaughan RA; Kriek E; Grant S; Uhl GR; Kuhar MJ -
Rate of binding of various inhibitors at the dopamine transporter in vivo.
Psychopharmacology (Berl) Volume: 119 Page(s): 376 - 384
06/01/1995 Authors: Stathis M; Scheffel U; Lever SZ; Boja JW; Carroll FI; Kuhar MJ -
Long-lasting inhibition of in vivo cocaine binding to dopamine transporters by 3 beta-(4-iodophenyl)tropane-2-carboxylic acid methyl ester: RTI-55 or beta CIT.
Synapse Volume: 19 Page(s): 206 - 211
03/01/1995 Authors: Volkow ND; Gatley SJ; Fowler JS; Chen R; Logan J; Dewey SL; Ding YS; Pappas N; King P; MacGregor RR -
INFLUENCE OF ENAMEL SURFACE ACID-ETCHING AND GRINDING ON MOLECULAR-DIFFUSION
Volume: 74 Page(s): 944 - 944
03/01/1995 Authors: KUHAR M; FUNDUK N; CEVC P; SCHARA M -
Cocaine and 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid ester and amide analogues. New high-affinity and selective compounds for the dopamine transporter.
J Med Chem Volume: 38 Page(s): 379 - 388
01/20/1995 Authors: Carroll FI; Kotian P; Dehghani A; Gray JL; Kuzemko MA; Parham KA; Abraham P; Lewin AH; Boja JW; Kuhar MJ -
Developmentally regulated glycosylation of dopamine transporter.
Brain Res Dev Brain Res Volume: 83 Page(s): 53 - 58
11/18/1994 Authors: Patel AP; Cerruti C; Vaughan RA; Kuhar MJ -
Regulation of neurotransmitter reuptake by nitric oxide.
Ann N Y Acad Sci Volume: 738 Page(s): 305 - 315
11/17/1994 Authors: Pgn S; Kuhar MJ -
Synthesis, ligand binding, and QSAR (CoMFA and classical) study of 3 beta-(3'-substituted phenyl)-, 3 beta-(4'-substituted phenyl)-, and 3 beta-(3',4'-disubstituted phenyl)tropane-2 beta-carboxylic acid methyl esters.
J Med Chem Volume: 37 Page(s): 2865 - 2873
09/02/1994 Authors: Carroll FI; Mascarella SW; Kuzemko MA; Gao Y; Abraham P; Lewin AH; Boja JW; Kuhar MJ -
Nitric oxide inhibits 3H-glutamate transport in synaptosomes.
Synapse Volume: 18 Page(s): 21 - 26
09/01/1994 Authors: Pogun S; Dawson V; Kuhar MJ -
SYNTHESIS AND LIGAND-BINDING OF TROPANE ANALOGS - NEW SELECTIVE COMPOUNDS FOR THE SEROTONIN TRANSPORTER
Volume: 208 Page(s): 181 - MEDI
08/21/1994 Authors: KEVERLINE KI; BOJA JW; KUHAR MJ; ABRAHAM P; LEWIN AH; CARROLL FI -
HALOGENATED MAZINDOL ANALOGS AS POTENTIAL INHIBITORS OF THE COCAINE BINDING-SITE AT THE DOPAMINE TRANSPORTER
Volume: 208 Page(s): 185 - MEDI
08/21/1994 Authors: HOULIHAN WJ; BOJA JW; PARRINO VA; KUHAR MJ; KOPAJTIC TA -
Withdrawal of repeated intravenous infusions of cocaine persistently reduces binding to dopamine transporters in the nucleus accumbens of Lewis rats.
J Pharmacol Exp Ther Volume: 269 Page(s): 963 - 969
06/01/1994 Authors: Pilotte NS; Sharpe LG; Kuhar MJ -
EFFECT OF RESERPINE UPON BINDING OF H-3 WIN-35,428 TO DOPAMINE UPTAKE SITES
Volume: 35 Page(s): P199 - P199
05/01/1994 Authors: KIM SE; SCHEFFEL U; BOJA JW; KUHAR MJ -
Secondary amine analogues of 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid esters and N-norcocaine exhibit enhanced affinity for serotonin and norepinephrine transporters.
J Med Chem Volume: 37 Page(s): 1220 - 1223
04/15/1994 Authors: Boja JW; Kuhar MJ; Kopajtic T; Yang E; Abraham P; Lewin AH; Carroll FI -
Occupancy of the serotonin transporter by fluoxetine, paroxetine, and sertraline: in vivo studies with [125I]RTI-55.
Synapse Volume: 16 Page(s): 263 - 268
04/01/1994 Authors: Scheffel U; Kim S; Cline EJ; Kuhar MJ -
DOPAMINE TRANSPORTER AND SYNAPTIC VESICULAR MONOAMINE TRANSPORTER EXPRESSION AND PARKINSONS-DISEASE DOPAMINERGIC DAMAGE
Volume: 44 Page(s): A282 - A282
04/01/1994 Authors: UHL GR; SURRATT C; VAUGHN R; KUHAR MJ; MASH D; JAVOYAGID F -
DOPAMINE TRANSPORTER AND SYNAPTIC VESICULAR MONOAMINE TRANSPORTER EXPRESSION AND PARKINSONS-DISEASE DOPAMINERGIC DAMAGE
Volume: 44 Page(s): A282 - A282
04/01/1994 Authors: UHL GR; SURRATT C; VAUGHN R; KUHAR MJ; MASH D; JAVOYAGID F -
Nitric oxide inhibits [3H]dopamine uptake.
Brain Res Volume: 641 Page(s): 83 - 91
03/28/1994 Authors: Pogun S; Baumann MH; Kuhar MJ -
Reduction in dopamine transporter mRNA after cessation of repeated cocaine administration.
Brain Res Mol Brain Res Volume: 22 Page(s): 132 - 138
03/01/1994 Authors: Cerruti C; Pilotte NS; Uhl G; Kuhar MJ -
Development of PET/SPECT ligands for the serotonin transporter.
NIDA Res Monogr Volume: 138 Page(s): 111 - 130
01/01/1994 Authors: Scheffel U; Dannals RF; Suehiro M; Ricaurte GA; Carroll FI; Kuhar MJ; Wagner HN -
Recent progress in dopamine transporter research
Volume: 4 Page(s): 248 - 249
01/01/1994 Authors: Kuhar MJ -
[11C]RTI-121 - A potential radioligand for PET studies of the dopamine transporter
Volume: 35 Page(s): 483 - 484
01/01/1994 Authors: Brown DJ; Luthra SK; Brown GD; Carroll FI; Kuhar MJ; Osman S; Waters SL; Brady F -
Synthesis and cocaine receptor affinities of 3-phenyl-2-(3-methyl-1, 2,4-oxadiazole-5-yl)tropane isomers
Journal of the Chemical Society, Chemical Communications Page(s): 44 - 46
12/01/1993 Authors: Carroll FI; Abraham P; Kuzemko MA; Gray JL; Lewin AH; Boja JW; Kuhar MJ -
3-Aryl-2-(3'-substituted-1',2',4'-oxadiazol-5'-yl)tropane analogues of cocaine: affinities at the cocaine binding site at the dopamine, serotonin, and norepinephrine transporters.
J Med Chem Volume: 36 Page(s): 2886 - 2890
10/01/1993 Authors: Carroll FI; Gray JL; Abraham P; Kuzemko MA; Lewin AH; Boja JW; Kuhar MJ -
In vivo imaging of baboon and human dopamine transporters by positron emission tomography using [11C]WIN 35,428.
Synapse Volume: 15 Page(s): 130 - 142
10/01/1993 Authors: Wong DF; Yung B; Dannals RF; Shaya EK; Ravert HT; Chen CA; Chan B; Folio T; Scheffel U; Ricaurte GA -
Potent cocaine analogs inhibit [3H]dopamine uptake in rat mesencephalic cells in primary cultures: pharmacological selectivity of embryonic cocaine sites.
Brain Res Dev Brain Res Volume: 75 Page(s): 13 - 17
09/17/1993 Authors: Brouard A; Pelaprat D; Boja JW; Carroll FI; Vial M; Kuhar MJ; Rostene W -
Species differences in dopamine transporters: postmortem changes and glycosylation differences.
J Neurochem Volume: 61 Page(s): 496 - 500
08/01/1993 Authors: Patel A; Uhl G; Kuhar MJ -
DOPAMINE TRANSPORTER EXPRESSION CORRELATES WITH PARKINSONS-DISEASE DOPAMINERGIC DAMAGE
Volume: 34 Page(s): 247 - 247
08/01/1993 Authors: UHL GR; KITAYAMA S; CERRUTI C; KUHAR MJ; SHIMADA S; MASH D; JAVOYAGID F -
INVIVO DOPAMINE TRANSPORTER SITES IMAGING IN HUMAN USING [C-11] WIN 35,428 POSITRON EMISSION TOMOGRAPHY (PET)
Volume: 34 Page(s): P197 - P197
05/01/1993 Authors: YUNG BCK; DANNALS RF; KUHAR MJ; SHAYA EK; RAVERT HT; CHEN C; CHAN B; SCHEFFEL U; RICAURTE G; FOLIO T -
Recognition of dopamine transporters by antipeptide antibodies.
Mol Cell Neurosci Volume: 4 Page(s): 209 - 215
04/01/1993 Authors: Vaughan RA; Uhl G; Kuhar MJ -
Dopamine transporter mRNA expression is intense in rat midbrain neurons and modest outside midbrain.
Brain Res Mol Brain Res Volume: 18 Page(s): 181 - 186
04/01/1993 Authors: Cerruti C; Walther DM; Kuhar MJ; Uhl GR -
SYNTHESIS AND COCAINE RECEPTOR AFFINITIES OF 3-PHENYL-2-(3'-METHYL-1,2,4-OXADIAZOLE-5'-YL)TROPANE ISOMERS
Volume: 205 Page(s): 84 - MEDI
03/28/1993 Authors: CARROLL FI; ABRAHAM P; KUZEMKO MA; GRAY JL; LEWIN AH; BOJA JW; KUHAR MJ -
Cocaine receptor: a structure-activity relationship study.
NIDA Res Monogr Volume: 134 Page(s): 229 - 237
01/01/1993 Authors: Carroll FI; Lewin AH; Kuhar MJ; Boja JW -
Neurotransmitter transporters: recent progress.
Annu Rev Neurosci Volume: 16 Page(s): 73 - 93
01/01/1993 Authors: Amara SG; Kuhar MJ -
Psychostimulant drugs and a dopamine hypothesis regarding addiction: update on recent research.
Biochem Soc Symp Volume: 59 Page(s): 51 - 64
01/01/1993 Authors: Ritz MC; Kuhar MJ -
WITHDRAWAL OF COCAINE REDUCES THE DOPAMINE TRANSPORTER MESSENGER-RNA EXPRESSION IN 2 VENTRAL TEGMENTAL AREA SUBNUCLEI
Volume: 61 Page(s): S69 - S69
01/01/1993 Authors: CERRUTI C; PILOTTE N; UHL G; KUHAR MJ -
Structural modifications of cocaine: Increased selectivity for the dopamine transporter
Page(s): 129
01/01/1993 Authors: Boja JW; Carroll FI; Lewin AH; Abraham P; Parham K; Kopajtic T; Milberger M; McNeill RM; Kuhar MJ -
Selective dopamine transporter inhibition by cocaine analogs.
Neuroreport Volume: 3 Page(s): 984 - 986
11/01/1992 Authors: Boja JW; McNeill RM; Lewin AH; Abraham P; Carroll FI; Kuhar MJ -
Dopamine transporter imaging with novel, selective cocaine analogs.
Neuroreport Volume: 3 Page(s): 969 - 972
11/01/1992 Authors: Scheffel U; Dannals RF; Wong DF; Yokoi F; Carroll FI; Kuhar MJ -
In vivo binding of [125I]RTI-55 to dopamine transporters: pharmacology and regional distribution with autoradiography.
Synapse Volume: 12 Page(s): 37 - 46
09/01/1992 Authors: Cline EJ; Scheffel U; Boja JW; Mitchell WM; Carroll FI; Abraham P; Lewin AH; Kuhar MJ -
High-affinity binding of [125I]RTI-55 to dopamine and serotonin transporters in rat brain.
Synapse Volume: 12 Page(s): 27 - 36
09/01/1992 Authors: Boja JW; Mitchell WM; Patel A; Kopajtic TA; Carroll FI; Lewin AH; Abraham P; Kuhar MJ -
Dopamine transport: pharmacological distinction between the synaptic membrane and the vesicular transporter in rat striatum.
Eur J Pharmacol Volume: 218 Page(s): 175 - 177
07/21/1992 Authors: Rostne W; Boja JW; Scherman D; Carroll FI; Kuhar MJ -
Microheterogeneity of dopamine transporters in rat striatum and nucleus accumbens.
Brain Res Volume: 584 Page(s): 266 - 271
07/03/1992 Authors: Lew R; Patel A; Vaughan RA; Wilson A; Kuhar MJ -
High potency cocaine analogs: neurochemical, imaging, and behavioral studies.
Ann N Y Acad Sci Volume: 654 Page(s): 282 - 291
06/28/1992 Authors: Boja JW; Cline EJ; Carroll FI; Lewin AH; Philip A; Dannals R; Wong D; Scheffel U; Kuhar MJ -
HIGH POTENCY COCAINE ANALOGS - NEUROCHEMICAL, IMAGING, AND BEHAVIORAL-STUDIES
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES Volume: 654 Page(s): 282 - 291
06/28/1992 Authors: BOJA JW; CLINE EJ; CARROLL FI; LEWIN AH; PHILIP A; DANNALS R; WONG D; SCHEFFEL U; KUHAR MJ -
Isopropyl and phenyl esters of 3 beta-(4-substituted phenyl)tropan-2 beta-carboxylic acids. Potent and selective compounds for the dopamine transporter.
J Med Chem Volume: 35 Page(s): 2497 - 2500
06/26/1992 Authors: Carroll FI; Abraham P; Lewin AH; Parham KA; Boja JW; Kuhar M -
[123/125I]RTI-55, an in vivo label for the serotonin transporter.
Synapse Volume: 11 Page(s): 134 - 139
06/01/1992 Authors: Scheffel U; Dannals RF; Cline EJ; Ricaurte GA; Carroll FI; Abraham P; Lewin AH; Kuhar MJ -
Probes for the cocaine receptor. Potentially irreversible ligands for the dopamine transporter.
J Med Chem Volume: 35 Page(s): 1813 - 1817
05/15/1992 Authors: Carroll FI; Gao Y; Abraham P; Lewin AH; Lew R; Patel A; Boja JW; Kuhar MJ -
Stimulus generalization from cocaine to analogs with high in vitro affinity for dopamine uptake sites.
Behav Pharmacol Volume: 3 Page(s): 113 - 116
04/01/1992 Authors: Cline EJ; Terry P; Carroll FI; Kuhar MJ; Katz JL -
A cocaine analog and a GBR analog label the same protein in rat striatal membranes.
Brain Res Volume: 576 Page(s): 173 - 174
03/27/1992 Authors: Patel A; Boja JW; Lever J; Lew R; Simantov R; Carroll FI; Lewin AH; Philip A; Gao Y; Kuhar MJ -
Cocaine receptor: biochemical characterization and structure-activity relationships of cocaine analogues at the dopamine transporter.
J Med Chem Volume: 35 Page(s): 969 - 981
03/20/1992 Authors: Carroll FI; Lewin AH; Boja JW; Kuhar MJ -
Behavioral effects of novel cocaine analogs: a comparison with in vivo receptor binding potency.
J Pharmacol Exp Ther Volume: 260 Page(s): 1174 - 1179
03/01/1992 Authors: Cline EJ; Scheffel U; Boja JW; Carroll FI; Katz JL; Kuhar MJ -
Expression of a single dopamine transporter cDNA can confer two cocaine binding sites.
Neuroreport Volume: 3 Page(s): 247 - 248
03/01/1992 Authors: Boja JW; Markham L; Patel A; Uhl G; Kuhar MJ -
In vivo imaging of dopamine reuptake sites in the primate brain using single photon emission computed tomography (SPECT) and iodine-123 labeled RTI-55.
Synapse Volume: 10 Page(s): 169 - 172
02/01/1992 Authors: Shaya EK; Scheffel U; Dannals RF; Ricaurte GA; Carroll FI; Wagner HN; Kuhar MJ; Wong DF -
N-modified analogues of cocaine: synthesis and inhibition of binding to the cocaine receptor.
J Med Chem Volume: 35 Page(s): 141 - 144
01/01/1992 Authors: Abraham P; Pitner JB; Lewin AH; Boja JW; Kuhar MJ; Carroll FI -
2 beta-substituted analogues of cocaine. Synthesis and inhibition of binding to the cocaine receptor.
J Med Chem Volume: 35 Page(s): 135 - 140
01/01/1992 Authors: Lewin AH; Gao YG; Abraham P; Boja JW; Kuhar MJ; Carroll FI -
Molecular pharmacology of cocaine: a dopamine hypothesis and its implications.
Ciba Found Symp Volume: 166 Page(s): 81 - 89
01/01/1992 Authors: Kuhar MJ -
Molecular mechanisms associated with cocaine effects. Possible relationships with effects of ethanol.
Recent Dev Alcohol Volume: 10 Page(s): 273 - 302
01/01/1992 Authors: Ritz MC; Kuhar MJ; George FR -
MOLECULAR PHARMACOLOGY OF COCAINE - A DOPAMINE HYPOTHESIS AND ITS IMPLICATIONS
Volume: 166 Page(s): 81 - 95
01/01/1992 Authors: KUHAR MJ -
AIDS AND HIV-INFECTION IN COCAINE USERS
Volume: 166 Page(s): 181 - 194
01/01/1992 Authors: JARLAIS DCD; EDWARDS G; MOORE MH; ALMOND B; KLEBER HD; NEGRETE; JONES JC; WOOLVERTON WL; MUSTO DF; KALANT H -
AIDS AND HIV-INFECTION IN COCAINE USERS
CIBA FOUNDATION SYMPOSIA Volume: 166 Page(s): 181 - 194
01/01/1992 Authors: JARLAIS DCD; EDWARDS G; MOORE MH; ALMOND B; KLEBER HD; NEGRETE; JONES JC; WOOLVERTON WL; MUSTO DF; KALANT H -
2-Substituted Analogues of Cocaine. Synthesis and Inhibition of Binding to the Cocaine Receptor
Journal of Medicinal Chemistry Volume: 35 Page(s): 135 - 140
01/01/1992 Authors: Lewin AH; Gao Y; Abraham P; Boja JW; Kuhar MJ; Carroll FI -
A rapid binding assay for solubilized dopamine transporters using [3H]WIN 35,428.
J Neurosci Methods Volume: 40 Page(s): 9 - 16
11/01/1991 Authors: Vaughan RA; Simantov R; Lew R; Kuhar MJ -
Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA.
Science Volume: 254 Page(s): 576 - 578
10/25/1991 Authors: Shimada S; Kitayama S; Lin CL; Patel A; Nanthakumar E; Gregor P; Kuhar M; Uhl G -
Synthesis, ligand binding, QSAR, and CoMFA study of 3 beta-(p-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters.
J Med Chem Volume: 34 Page(s): 2719 - 2725
09/01/1991 Authors: Carroll FI; Gao YG; Rahman MA; Abraham P; Parham K; Lewin AH; Boja JW; Kuhar MJ -
X-RAY AFFINITY LABELING OF DOPAMINE TRANSPORTER BY PHOTOAFFINITY LIGANDS
Volume: 32 Page(s): 1839 - 1839
09/01/1991 Authors: WONG FCL; BOJA JW; WONG DF; WILSON AA; CARROLL FI; KUHAR MJ; WAGNER HN -
Neuroanatomic specificity and time course of alterations in rat brain serotonergic pathways induced by MDMA (3,4-methylenedioxymethamphetamine): assessment using quantitative autoradiography.
Synapse Volume: 8 Page(s): 249 - 260
08/01/1991 Authors: Battaglia G; Sharkey J; Kuhar MJ; de Souza EB -
The dopamine hypothesis of the reinforcing properties of cocaine.
Trends Neurosci Volume: 14 Page(s): 299 - 302
07/01/1991 Authors: Kuhar MJ; Ritz MC; Boja JW -
Cocaine displaces [3H]WIN 35,428 binding to dopamine uptake sites in vivo more rapidly than mazindol or GBR 12909.
Eur J Pharmacol Volume: 198 Page(s): 203 - 205
06/06/1991 Authors: Pgn S; Scheffel U; Kuhar MJ -
In vivo labeling of cocaine binding sites on dopamine transporters with [3H]WIN 35,428.
J Pharmacol Exp Ther Volume: 257 Page(s): 954 - 958
06/01/1991 Authors: Scheffel U; Pgn S; Stathis M; Boja JW; Kuhar MJ -
Dopamine transporters in the nucleus accumbens and the striatum have different apparent molecular weights.
Synapse Volume: 8 Page(s): 152 - 153
06/01/1991 Authors: Lew R; Vaughan R; Simantov R; Wilson A; Kuhar MJ -
INVIVO LABELING OF COCAINE BINDING-SITES ON DOPAMINE TRANSPORTERS WITH [H-3] WIN-35,428
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS Volume: 257 Page(s): 954 - 958
06/01/1991 Authors: SCHEFFEL U; POGUN S; STATHIS M; BOJA JW; KUHAR MJ -
Synthesis and ligand binding of cocaine isomers at the cocaine receptor.
J Med Chem Volume: 34 Page(s): 883 - 886
03/01/1991 Authors: Carroll FI; Lewin AH; Abraham P; Parham K; Boja JW; Kuhar MJ -
Isothiocyanate derivatives of cocaine: irreversible inhibition of ligand binding at the dopamine transporter.
Mol Pharmacol Volume: 39 Page(s): 339 - 345
03/01/1991 Authors: Boja JW; Rahman MA; Philip A; Lewin AH; Carroll FI; Kuhar MJ -
[125I]RTI-55: a potent ligand for dopamine transporters.
Eur J Pharmacol Volume: 194 Page(s): 133 - 134
02/26/1991 Authors: Boja JW; Patel A; Carroll FI; Rahman MA; Philip A; Lewin AH; Kopajtic TA; Kuhar MJ -
[I-125] RTI-55 - A POTENT LIGAND FOR DOPAMINE TRANSPORTERS
EUROPEAN JOURNAL OF PHARMACOLOGY Volume: 194 Page(s): 133 - 134
02/26/1991 Authors: BOJA JW; PATEL A; CARROLL FI; RAHMAN MA; PHILIP A; LEWIN AH; KOPAJTIC TA; KUHAR MJ -
[125I]RTI-55: a potent ligand for dopamine transporters
European Journal of Pharmacology Volume: 194 Page(s): 133 - 134
02/26/1991 Authors: Boja JW; Patel A; Ivy Carroll F; Abdur Rahman M; Philip A; Lewin AH; Kopajtic TA; Kuhar MJ -
Dopamine transporter: deglycosylation with exo- and endoglycosidases.
Brain Res Volume: 539 Page(s): 239 - 246
01/25/1991 Authors: Lew R; Grigoriadis D; Wilson A; Boja JW; Simantov R; Kuhar MJ -
Imaging receptors by autoradiography: computer-assisted approaches.
J Chem Neuroanat Volume: 4 Page(s): 319 - 327
01/01/1991 Authors: Kuhar MJ; Lloyd DG; Appel N; Loats HL -
DOPAMINE TRANSPORTER COCAINE RECEPTOR - CHARACTERIZATION AND PURIFICATION
Volume: 82 Page(s): 151 - 154
01/01/1991 Authors: SIMANTOV R; VAUGHAN R; LEW R; WILSON A; KUHAR MJ -
Emerging technologies and new directions in drug abuse research. An overview.
Volume: 112 Page(s): 1 - 6
01/01/1991 Authors: Snyder M -
A GABA transporter cDNA has been cloned.
Trends Neurosci Volume: 13 Page(s): 473 - 474
12/01/1990 Authors: Kuhar MJ -
Synthesis and receptor binding of cocaine analogs
Page(s): 147 - 153
12/01/1990 Authors: Carroll FI; Abdur Rahman M; Philip A; Lewin AH; Boja JW; Kuhar MJ -
[3H]WIN 35,065-2: a ligand for cocaine receptors in striatum.
J Neurochem Volume: 55 Page(s): 1556 - 1562
11/01/1990 Authors: Ritz MC; Boja JW; Grigoriadis D; Zaczek R; Carroll FI; Lewis AH; Kuhar MJ -
New, potent cocaine analogs: ligand binding and transport studies in rat striatum.
Eur J Pharmacol Volume: 184 Page(s): 329 - 332
08/10/1990 Authors: Boja JW; Carroll FI; Rahman MA; Philip A; Lewin AH; Kuhar MJ -
The dopamine transporter: binding by the irreversible ligands meta- and para-isothiocyanatobenzoylecgonine methyl ester
European Journal of Pharmacology Volume: 183 Page(s): 654 - 655
07/03/1990 Authors: Boja JW; Carroll FI; Kuhar MJ -
THE DOPAMINE TRANSPORTER - BINDING BY THE IRREVERSIBLE LIGANDS META-ISOTHIOCYANATOBENZOYLECGONINE AND PARA-ISOTHIOCYANATOBENZOYLECGONINE METHYL-ESTER
Volume: 183 Page(s): 654 - 655
07/01/1990 Authors: BOJA JW; CARROLL FI; KUHAR MJ -
Phencyclidine binding to striatal cocaine receptors.
Neuropharmacology Volume: 29 Page(s): 295 - 297
03/01/1990 Authors: Kuhar MJ; Boja JW; Cone EJ -
Synthesis and receptor binding of cocaine analogs.
NIDA Res Monogr Volume: 105 Page(s): 147 - 153
01/01/1990 Authors: Carroll FI; Rahman MA; Philip A; Lewin AH; Boja JW; Kuhar MJ -
Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity study.
Life Sci Volume: 46 Page(s): 635 - 645
01/01/1990 Authors: Ritz MC; Cone EJ; Kuhar MJ -
Anterograde transport of opioid receptors in rat vagus nerves and dorsal roots of spinal nerves: pharmacology and sensitivity to sodium and guanine nucleotides.
Exp Brain Res Volume: 81 Page(s): 267 - 278
01/01/1990 Authors: Zarbin MA; Wamsley JK; Kuhar MJ -
Dopamine transporter: biochemistry, pharmacology and imaging.
Eur Neurol Volume: 30 Suppl 1 Page(s): 15 - 20
01/01/1990 Authors: Kuhar MJ; Sanchez-Roa PM; Wong DF; Dannals RF; Grigoriadis DE; Lew R; Milberger M -
Synthesis of [3H]win 35,0652; A new radioligand for cocaine receptors
Journal of Labelled Compounds and Radiopharmaceuticals Volume: 28 Page(s): 1011 - 1016
01/01/1990 Authors: Naseree TM; Abraham P; Kepler JA; Carroll FI; Lewin AH; Kuhar MJ -
[3H]WIN 35,0652: A Ligand for Cocaine Receptors in Striatum
Journal of Neurochemistry Volume: 55 Page(s): 1556 - 1562
01/01/1990 Authors: Ritz MC; Boja JW; Grigoriadis D; Zaczek R; Carroll FI; Lewis AH; Kuhar MJ -
[3H]cocaine binding and inhibition of [3H]dopamine uptake is similar in both the rat striatum and nucleus accumbens.
Eur J Pharmacol Volume: 173 Page(s): 215 - 217
12/07/1989 Authors: Boja JW; Kuhar MJ -
[H-3] COCAINE BINDING AND INHIBITION OF [H-3] DOPAMINE UPTAKE IS SIMILAR IN BOTH THE RAT STRIATUM AND NUCLEUS ACCUMBENS
EUROPEAN JOURNAL OF PHARMACOLOGY Volume: 173 Page(s): 215 - 217
12/07/1989 Authors: BOJA JW; KUHAR MJ -
[3H]cocaine binding and inhibition of [3H]dopamine uptake is similar in both the rat striatum and nucleus accumbens
European Journal of Pharmacology Volume: 173 Page(s): 215 - 217
12/07/1989 Authors: Boja JW; Kuhar MJ -
Mu opiate receptors are selectively labelled by [3H]carfentanil in human and rat brain.
Eur J Pharmacol Volume: 167 Page(s): 221 - 228
08/22/1989 Authors: Titeler M; Lyon RA; Kuhar MJ; Frost JF; Dannals RF; Leonhardt S; Bullock A; Rydelek LT; Price DL; Struble RG -
Dopamine transport sites selectively labeled by a novel photoaffinity probe: 125I-DEEP.
J Neurosci Volume: 9 Page(s): 2664 - 2670
08/01/1989 Authors: Grigoriadis DE; Wilson AA; Lew R; Sharkey JS; Kuhar MJ -
Relationship between self-administration of amphetamine and monoamine receptors in brain: comparison with cocaine.
J Pharmacol Exp Ther Volume: 248 Page(s): 1010 - 1017
03/01/1989 Authors: Ritz MC; Kuhar MJ -
Dopamine transporter: solubilization from dog caudate nucleus.
Synapse Volume: 3 Page(s): 372 - 375
01/01/1989 Authors: Lew R; Grigoriadis DE; Sharkey J; Kuhar MJ -
Cocaine receptors: in vivo labeling with 3H-(-)cocaine, 3H-WIN 35,065-2, and 3H-WIN 35,428.
Synapse Volume: 4 Page(s): 390 - 392
01/01/1989 Authors: Scheffel U; Boja JW; Kuhar MJ -
Modulation of the lethal effects of cocaine by cholinomimetics.
Life Sci Volume: 45 Page(s): 2295 - 2301
01/01/1989 Authors: Witkin JM; Goldberg SR; Katz JL; Kuhar MJ -
Differential effects of the pharmacological manipulation of serotonin systems on cocaine and amphetamine self-administration in rats.
Life Sci Volume: 45 Page(s): 1529 - 1535
01/01/1989 Authors: Porrino LJ; Ritz MC; Goodman NL; Sharpe LG; Kuhar MJ; Goldberg SR -
Cocaine binding sites related to drug self-administration.
NIDA Res Monogr Volume: 95 Page(s): 239 - 246
01/01/1989 Authors: Ritz MC; Boja JW; George FR; Kuhar MJ -
[125]I-spectramide: a novel benzamide displaying potent and selective effects at the D2 dopamine receptor.
Life Sci Volume: 45 Page(s): 1821 - 1829
01/01/1989 Authors: Snchez-Roa PM; Grigoriadis DE; Wilson AA; Sharkey J; Dannals RF; Villemagne VL; Wong DF; Wagner HN; Kuhar MJ -
[125]I-Spectramide: A novel benzamide displaying potent and selective effects at the D
2 dopamine receptor
Life Sciences Volume: 45 Page(s): 1821 - 1829
01/01/1989 Authors: Snchez-Roa PM; Grigoriadis DE; Wilson AA; Sharkey J; Dannals RF; Villemagne VL; Wong DF; Wagner HN; Kuhar MJ -
Amphetamine and cocaine self-administration are mediated by different mechanisms: The influence of dopamine and serotonin transporters
Page(s): 339
12/01/1988 Authors: Ritz M; Kuhar M -
Differential effects of the manipulation of serotonin systems on intravenous amphetamine and cocaine self-administration in rats
Page(s): 29
12/01/1988 Authors: Porrino L; Sharpe L; Ritz M; Goodman N; Goldberg S; Kuhar M -
Cocaine inhibits muscarinic cholinergic receptors in heart and brain.
J Pharmacol Exp Ther Volume: 246 Page(s): 1048 - 1052
09/01/1988 Authors: Sharkey J; Ritz MC; Schenden JA; Hanson RC; Kuhar MJ -
Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity.
J Neurosci Volume: 8 Page(s): 2788 - 2803
08/01/1988 Authors: O'Hearn E; Battaglia G; De Souza EB; Kuhar MJ; Molliver ME -
Cocaine binding at sigma receptors.
Eur J Pharmacol Volume: 149 Page(s): 171 - 174
04/27/1988 Authors: Sharkey J; Glen KA; Wolfe S; Kuhar MJ -
Buspirone enhances benzodiazepine receptor binding in vivo.
Neuropharmacology Volume: 27 Page(s): 275 - 280
03/01/1988 Authors: Goeders NE; Ritz MC; Kuhar MJ -
Cocaine self-administration appears to be mediated by dopamine uptake inhibition.
Prog Neuropsychopharmacol Biol Psychiatry Volume: 12 Page(s): 233 - 239
01/01/1988 Authors: Ritz MC; Lamb RJ; Goldberg SR; Kuhar MJ -
Neuroimaging and neuropathology.
Schizophr Bull Volume: 14 Page(s): 383 - 397
01/01/1988 Authors: Wagner HN; Weinberger DR; Kleinman JE; Casanova MF; Gibbs CJ; Gur RE; Hornykiewicz O; Kuhar MJ; Pettegrew JW; Seeman P -
Cocaine receptors on dopamine transporters mediate cocaine-reinforced behavior.
NIDA Res Monogr Volume: 88 Page(s): 14 - 22
01/01/1988 Authors: Kuhar MJ; Ritz MC; Sharkey J -
In vivo PET and SPECT receptor imaging: new technology and tactics for receptor measurement.
Adv Exp Med Biol Volume: 236 Page(s): 181 - 193
01/01/1988 Authors: Wong DF; Kuhar MJ -
Nalbuphine: an autoradiographic opioid receptor binding profile in the central nervous system of an agonist/antagonist analgesic.
J Pharmacol Exp Ther Volume: 244 Page(s): 391 - 402
01/01/1988 Authors: De Souza EB; Schmidt WK; Kuhar MJ -
Cocaine receptors on dopamine transporters are related to self-administration of cocaine.
Science Volume: 237 Page(s): 1219 - 1223
09/04/1987 Authors: Ritz MC; Lamb RJ; Goldberg SR; Kuhar MJ -
3,4-Methylenedioxymethamphetamine and 3,4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by measurement of [3H]paroxetine-labeled serotonin uptake sites.
J Pharmacol Exp Ther Volume: 242 Page(s): 911 - 916
09/01/1987 Authors: Battaglia G; Yeh SY; O'Hearn E; Molliver ME; Kuhar MJ; De Souza EB -
-Adrenergic receptors in human trabecular meshwork. Identification and autoradiographic localization
Investigative Ophthalmology and Visual Science Volume: 28 Page(s): 772 - 779
07/09/1987 Authors: Jampel HD; Lynch MG; Brown RH; Kuhar MJ; De Souza EB -
Imaging receptors for drugs in neural tissue.
Neuropharmacology Volume: 26 Page(s): 911 - 916
07/01/1987 Authors: Kuhar MJ -
Reductions in corticotropin releasing factor-like immunoreactivity in cerebral cortex in Alzheimer's disease, Parkinson's disease, and progressive supranuclear palsy.
Neurology Volume: 37 Page(s): 905 - 909
06/01/1987 Authors: Whitehouse PJ; Vale WW; Zweig RM; Singer HS; Mayeux R; Kuhar MJ; Price DL; De Souza EB -
Beta-adrenergic receptors in human trabecular meshwork. Identification and autoradiographic localization.
Invest Ophthalmol Vis Sci Volume: 28 Page(s): 772 - 779
05/01/1987 Authors: Jampel HD; Lynch MG; Brown RH; Kuhar MJ; De Souza EB -
In vivo binding of 3H-N-methylspiperone to dopamine and serotonin receptors.
Life Sci Volume: 40 Page(s): 987 - 995
03/09/1987 Authors: Frost JJ; Smith AC; Kuhar MJ; Dannals RF; Wagner HN -
INVIVO BINDING OF H-3 N-METHYLSPIPERONE TO DOPAMINE AND SEROTONIN RECEPTORS
LIFE SCIENCES Volume: 40 Page(s): 987 - 995
03/09/1987 Authors: FROST JJ; SMITH AC; KUHAR MJ; DANNALS RF; WAGNER HN -
In vivo binding of 3H-N-methylspiperone to dopamine and serotonin receptors
Life Sciences Volume: 40 Page(s): 1007 - 1015
03/09/1987 Authors: Frost JJ; Smith AC; Kuhar MJ; Dannals RF; Wagner HN -
THE COCAINE RECEPTOR - BEHAVIORAL POTENCY CORRELATES WITH MONOAMINE UPTAKE INHIBITION
Volume: 46 Page(s): 404 - 404
03/01/1987 Authors: RITZ MC; KUHAR MJ -
MDMA-INDUCED NEUROTOXICITY VISUALIZED BY INVITRO AUTORADIOGRAPHY - DIFFERENTIAL SENSITIVITY OF SEROTONERGIC NEURONS
Volume: 46 Page(s): 404 - 404
03/01/1987 Authors: BATTAGLIA G; KUHAR MJ; DESOUZA EB -
Chronic cocaine administration induces opposite changes in dopamine receptors in the striatum and nucleus accumbens.
Alcohol Drug Res Volume: 7 Page(s): 207 - 216
01/01/1987 Authors: Goeders NE; Kuhar MJ -
Recent progress in receptor mapping: Which neurons contain the receptors?
Trends in Neurosciences Volume: 10 Page(s): 308 - 310
01/01/1987 Authors: Kuhar MJ -
POSITRON-EMITTING TRACERS AND INVIVO BRAIN CHEMISTRY
Volume: 32 Page(s): 768 - 768
01/01/1987 Authors: WAGNER HN; DANNALS RF; WONG DF; FROST JJ; LINKS JM; SNYDER SH; KUHAR MJ -
HUMAN-BRAIN IMAGING
Page(s): 174 - 174
01/01/1987 Authors: KUHAR MJ -
Imaging receptors for drugs in neural tissue
Neuropharmacology Volume: 26 Page(s): 911 - 916
01/01/1987 Authors: Kuhar MJ -
Positron emission tomography reveals elevated D2 dopamine receptors in drug-naive schizophrenics.
Science Volume: 234 Page(s): 1558 - 1563
12/19/1986 Authors: Wong DF; Wagner HN; Tune LE; Dannals RF; Pearlson GD; Links JM; Tamminga CA; Broussolle EP; Ravert HT; Wilson AA -
Benzodiazepine receptor GABA ratios: regional differences in rat brain and modulation by adrenalectomy.
Eur J Pharmacol Volume: 129 Page(s): 363 - 366
10/07/1986 Authors: Goeders NE; De Souza EB; Kuhar MJ -
3H-3-N-methylspiperone labels D2 dopamine receptors in basal ganglia and S2 serotonin receptors in cerebral cortex.
J Neurosci Volume: 6 Page(s): 2941 - 2949
10/01/1986 Authors: Lyon RA; Titeler M; Frost JJ; Whitehouse PJ; Wong DF; Wagner HN; Dannals RF; Links JM; Kuhar MJ -
H-3 3-N-METHYLSPIPERONE LABELS D2 DOPAMINE-RECEPTORS IN BASAL GANGLIA AND S2 SEROTONIN RECEPTORS IN CEREBRAL-CORTEX
JOURNAL OF NEUROSCIENCE Volume: 6 Page(s): 2941 - 2949
10/01/1986 Authors: LYON RA; TITELER M; FROST JJ; WHITEHOUSE PJ; WONG DF; WAGNER HN; DANNALS RF; LINKS JM; KUHAR MJ -
Benzodiazepine receptors in rat brain are altered by adrenalectomy.
Brain Res Volume: 381 Page(s): 176 - 181
08/27/1986 Authors: De Souza EB; Goeders NE; Kuhar MJ -
REDUCTIONS IN CORTICOTROPIN-RELEASING FACTOR-LIKE IMMUNOREACTIVITY IN CEREBRAL-CORTEX IN ALZHEIMERS-DISEASE, PARKINSONS-DISEASE, AND PROGRESSIVE SUPRANUCLEAR PALSY
Volume: 20 Page(s): 125 - 126
07/01/1986 Authors: WHITEHOUSE PJ; ZWEIG RM; KUHAR MJ; PRICE DL; VALET WW; DESOUZA EB -
Response: human brain receptor distribution.
Science Volume: 232 Page(s): 1270 - 1271
06/06/1986 Authors: Wong DF; Wagner HN; Dannals RF; Links JM; Kuhar MJ; Gjedde A -
Human brain receptor distribution.
Science Volume: 232 Page(s): 1269 - 1271
06/06/1986 Authors: Frey KA; Agranoff BW; Young AB; Hichwa RD; Ehrenkaufer RL -
Autoradiographic localization of high affinity GABA, benzodiazepine, dopaminergic, adrenergic and muscarinic cholinergic receptors in the rat, monkey and human retina.
Brain Res Volume: 374 Page(s): 75 - 92
05/21/1986 Authors: Zarbin MA; Wamsley JK; Palacios JM; Kuhar MJ -
Quantification of Neuroreceptors in the living human brain. II. Inhibition studies of receptor density and affinity.
J Cereb Blood Flow Metab Volume: 6 Page(s): 147 - 153
04/01/1986 Authors: Wong DF; Gjedde A; Wagner HN; Dannals RF; Douglass KH; Links JM; Kuhar MJ -
ALZHEIMERS-DISEASE - RECIPROCAL CHANGES IN CORTICOTROPIN-RELEASING FACTOR (CRF)-LIKE IMMUNOREACTIVITY AND CRF RECEPTORS IN CEREBRAL-CORTEX
Volume: 36 Page(s): 271 - 271
04/01/1986 Authors: DESOUZA EB; WHITEHOUSE PJ; PRICE DL; VALE WW; KUHAR MJ -
REDUCTIONS OF SEROTONIN RECEPTORS IN ALZHEIMERS-DISEASE - AN AUTORADIOGRAPHIC STUDY
Volume: 36 Page(s): 270 - 270
04/01/1986 Authors: GONZALEZ J; WHITEHOUSE PJ; ZWEIG RM; YAGALOFF KA; HARTIG PR; MARCUS K; KUHAR MJ; PRICE DL; STEELE CS; FOLSTEIN MF -
REDUCTIONS IN NEUROTRANSMITTER RECEPTORS IN THE NUCLEUS BASALIS OF MEYNERT IN ALZHEIMERS-DISEASE
Volume: 36 Page(s): 273 - 273
04/01/1986 Authors: WHITEHOUSE PJ; MARCUS K; PRICE DL; KUHAR MJ; WAGSTER WV -
Reciprocal changes in corticotropin-releasing factor (CRF)-like immunoreactivity and CRF receptors in cerebral cortex of Alzheimer's disease.
Nature Volume: 319 Page(s): 593 - 595
02/13/1986 Authors: De Souza EB; Whitehouse PJ; Kuhar MJ; Price DL; Vale WW -
Corticotropin-releasing factor receptors: autoradiographic identification.
Res Publ Assoc Res Nerv Ment Dis Volume: 64 Page(s): 179 - 198
01/01/1986 Authors: De Souza EB; Kuhar MJ -
Corticotropin-releasing factor receptors in the pituitary gland and central nervous system: methods and overview.
Methods Enzymol Volume: 124 Page(s): 560 - 590
01/01/1986 Authors: De Souza EB; Kuhar MJ -
Neurotransmitter receptor mapping by autoradiography and other methods.
Annu Rev Neurosci Volume: 9 Page(s): 27 - 59
01/01/1986 Authors: Kuhar MJ; De Souza EB; Unnerstall JR -
Neuroanatomical substrates of anxiety: a brief survey
Trends in Neurosciences Volume: 9 Page(s): 307 - 311
01/01/1986 Authors: Kuhar MJ -
IMAGING DOPAMINE-RECEPTORS IN THE HUMAN-BRAIN
Volume: 31 Page(s): 3 - 3
01/01/1986 Authors: WAGNER HN; WONG DF; DANNALS RF; KUHAR MJ; LINKS JM; FROST JJ; FOLSTEIN M; FOLSTEIN S -
OPIATE RECEPTOR IMAGING IN THE LIVING HUMAN-BRAIN
Volume: 31 Page(s): 225 - 225
01/01/1986 Authors: WAGNER HN; FROST JJ; DANNALS RF; LINKS JM; BICE AN; KUHAR MJ; SNYDER SH -
Alpha-2 adrenergic agonist binding in schizophrenic brains
Psychopharmacology Bulletin Volume: 22 Page(s): 1011 - 1016
01/01/1986 Authors: Ko GN; Unnerstall JR; Kuhar MJ -
Neuroanatomical substrates of anxiety: A brief survey
Trends in Neurosciences Volume: 9 Page(s): 311 - 313
01/01/1986 Authors: Kuhar MJ -
3H-3-N-methylspiperone labels D
2 dopamine receptors in basal ganglia and S2 serotonin receptors in cerebral cortex
Journal of Neuroscience Volume: 6 Page(s): 2941 - 2949
01/01/1986 Authors: Lyon RA; Titeler M; Frost JJ; Whitehouse PJ; Wang DF; Wagner HN; Dannals RF; Links JM; Kuhar MJ -
Corticotropin-releasing factor receptors are widely distributed within the rat central nervous system: an autoradiographic study.
J Neurosci Volume: 5 Page(s): 3189 - 3203
12/01/1985 Authors: De Souza EB; Insel TR; Perrin MH; Rivier J; Vale WW; Kuhar MJ -
Axonal transport of alpha-bungarotoxin binding sites in rat sciatic nerve.
Brain Res Volume: 340 Page(s): 269 - 276
08/12/1985 Authors: Millington WR; Aizenman E; Bierkamper GG; Zarbin MA; Kuhar MJ -
Neurotransmitter receptor alterations in Huntington's disease: autoradiographic and homogenate studies with special reference to benzodiazepine receptor complexes.
Ann Neurol Volume: 18 Page(s): 202 - 210
08/01/1985 Authors: Whitehouse PJ; Trifiletti RR; Jones BE; Folstein S; Price DL; Snyder SH; Kuhar MJ -
Benzodiazepine receptor binding in vivo with [3H]-Ro 15-1788.
Life Sci Volume: 37 Page(s): 345 - 355
07/29/1985 Authors: Goeders NE; Kuhar MJ -
Benzodiazepine receptor binding with a new ligand, Ro 22-8515.
Eur J Pharmacol Volume: 113 Page(s): 147 - 148
07/11/1985 Authors: Goeders NE; Horst WD; O'Brien R; Bautz G; Kuhar MJ -
[3H]Nitrendipine binding to calcium channels in bovine and rat pituitary.
J Neurochem Volume: 44 Page(s): 1955 - 1958
06/01/1985 Authors: Titeler M; De Souza EB; Kuhar MJ -
Differential regulation of corticotropin-releasing factor receptors in anterior and intermediate lobes of pituitary and in brain following adrenalectomy in rats.
Neurosci Lett Volume: 56 Page(s): 121 - 128
05/14/1985 Authors: De Souza EB; Insel TR; Perrin MH; Rivier J; Vale WW; Kuhar MJ -
Vasoactive intestinal peptide receptor localization in rat forebrain by autoradiography.
Neurosci Lett Volume: 56 Page(s): 113 - 120
05/14/1985 Authors: De Souza EB; Seifert H; Kuhar MJ -
Corticotropin-releasing factor receptors in human pituitary gland: autoradiographic localization.
Neuroendocrinology Volume: 40 Page(s): 419 - 422
05/01/1985 Authors: De Souza EB; Perrin MH; Whitehouse PJ; Rivier J; Vale W; Kuhar MJ -
Neurotransmitter receptors in amyotrophic lateral sclerosis: possible relationship to sparing of eye movements.
Ann Neurol Volume: 17 Page(s): 518
05/01/1985 Authors: Whitehouse PJ; Wamsley JK; Zarbin MA; Price DL; Kuhar MJ -
Depletion of peripheral-type benzodiazepine receptors after hypophysectomy in rat adrenal gland and testis.
Eur J Pharmacol Volume: 110 Page(s): 41 - 46
03/26/1985 Authors: Anholt RR; De Souza EB; Kuhar MJ; Snyder SH -
Autoradiographic localization of (125I-Tyr4)bombesin-binding sites in rat brain.
J Neurosci Volume: 5 Page(s): 429 - 437
02/01/1985 Authors: Zarbin MA; Kuhar MJ; O'Donohue TL; Wolf SS; Moody TW -
Imaging neuroreceptors in the human brain in health and disease.
Radioisotopes Volume: 34 Page(s): 103 - 107
02/01/1985 Authors: Wagner HN; Dannals RF; Frost JJ; Wong DF; Ravert HT; Wilson AA; Links JM; Burns HD; Kuhar MJ; Snyder SH -
Localization of beta adrenoceptor subtypes in rat kidney by light microscopic autoradiography.
J Pharmacol Exp Ther Volume: 232 Page(s): 561 - 569
02/01/1985 Authors: Summers RJ; Stephenson JA; Kuhar MJ -
Peripheral-type benzodiazepine receptors in endocrine organs: autoradiographic localization in rat pituitary, adrenal, and testis.
Endocrinology Volume: 116 Page(s): 567 - 573
02/01/1985 Authors: De Souza EB; Anholt RR; Murphy KM; Snyder SH; Kuhar MJ -
Dopamine receptor binding of C-11-3-N-methylspiperone in the caudate in schizophrenia and bipolar disorder: a preliminary report.
Psychopharmacol Bull Volume: 21 Page(s): 595 - 598
01/01/1985 Authors: Wong DF; Wagner HN; Pearlson G; Dannals RF; Links JM; Ravert HT; Wilson AA; Suneja S; Bjorvvinssen E; Kuhar MJ -
Atlas of dopamine receptor images (PET) of the human brain.
J Comput Assist Tomogr Volume: 9 Page(s): 129 - 140
01/01/1985 Authors: Inoue Y; Wagner HN; Wong DF; Links JM; Frost JJ; Dannals RF; Rosenbaum AE; Takeda K; Di Chiro G; Kuhar MJ -
Receptor mapping in neuropharmacology by autoradiography: some technical problems.
NIDA Res Monogr Volume: 62 Page(s): 1 - 12
01/01/1985 Authors: Kuhar MJ; Unnerstall JR; De Souza EB -
Imaging opiate receptors in the human brain by positron tomography.
J Comput Assist Tomogr Volume: 9 Page(s): 231 - 236
01/01/1985 Authors: Frost JJ; Wagner HN; Dannals RF; Ravert HT; Links JM; Wilson AA; Burns HD; Wong DF; McPherson RW; Rosenbaum AE -
INVIVO ASSESSMENT OF DOPAMINE D-2 AND SEROTONIN S-2 RECEPTORS MEASURED BY C-11 N-METHYLSPIPERONE (NMSP) IN MANIC-DEPRESSIVE ILLNESS
JOURNAL OF NUCLEAR MEDICINE Volume: 26 Page(s): P107 - P107
01/01/1985 Authors: WONG DF; PEARLSON G; WAGNER HN; DANNALS RF; SUNEJA S; BJORGVINSSON E; LINKS JM; RAVERT HT; WILSON AA; SCHAERF F -
Quantitative receptor mapping by autoradiography: some current technical problems
Trends in Neurosciences Volume: 8 Page(s): 49 - 53
01/01/1985 Authors: Kuhar MJ; Unnerstall JR -
INVIVO ASSESSMENT OF DOPAMINE AND SEROTONIN RECEPTORS MEASURED BY C-11 N-METHYLSPIPERONE (NMSP) IN PATIENTS WITH SCHIZOPHRENIA
JOURNAL OF NUCLEAR MEDICINE Volume: 26 Page(s): P107 - P107
01/01/1985 Authors: WONG DF; TUNE LE; WAGNER HN; SUNEJA S; BJORVINSSON E; PEARLSON G; DANNALS RF; RAVERT HT; WILSON AA; LINKS JM -
FURTHER DEVELOPMENT AND VALIDATION OF THE MODEL FOR INVIVO QUANTIFICATION OF HUMAN DOPAMINE-RECEPTORS
Volume: 26 Page(s): P52 - P52
01/01/1985 Authors: WONG DF; GJEDDE A; WAGNER HN; DOUGLASS KH; DANNALS RF; SNYDER SH; KUHAR MJ -
[3H]Nitrendipine Binding to Calcium Channels in Bovine and Rat Pituitary
Journal of Neurochemistry Volume: 44 Page(s): 1955 - 1958
01/01/1985 Authors: Titeler M; De Souza EB; Kuhar MJ -
The mismatch problem in receptor mapping studies
Trends in Neurosciences Volume: 8 Page(s): 190 - 191
01/01/1985 Authors: Kuhar MJ -
ASSESSMENT OF DOPAMINE RECEPTOR BLOCKADE BY NEUROLEPTIC DRUGS IN THE LIVING HUMAN-BRAIN
JOURNAL OF NUCLEAR MEDICINE Volume: 26 Page(s): P52 - P53
01/01/1985 Authors: WONG DF; WAGNER HN; COYLE J; SNYDER S; DANNALS R; LAFRANCE N; BICE A; PEARLSON G; LINKS J; PAULOS M -
DOPAMINE AND SEROTONIN RECEPTORS MEASURED INVIVO IN HUNTINGTONS-DISEASE WITH C-11 N-METHYLSPIPERONE PET IMAGING
JOURNAL OF NUCLEAR MEDICINE Volume: 26 Page(s): P107 - P107
01/01/1985 Authors: WONG DF; LINKS JM; WAGNER HN; FOLSTEIN SE; SUNEJA S; DANNALS RF; RAVERT HT; WILSON AA; TUNE LE; PEARLSON G -
Effects of age on dopamine and serotonin receptors measured by positron tomography in the living human brain.
Science Volume: 226 Page(s): 1393 - 1396
12/21/1984 Authors: Wong DF; Wagner HN; Dannals RF; Links JM; Frost JJ; Ravert HT; Wilson AA; Rosenbaum AE; Gjedde A; Douglass KH -
(3-N-[11C]methyl)spiperone, a ligand binding to dopamine receptors: radiochemical synthesis and biodistribution studies in mice.
J Nucl Med Volume: 25 Page(s): 1222 - 1227
11/01/1984 Authors: Burns HD; Dannals RF; Langstrm B; Ravert HT; Zemyan SE; Duelfer T; Wong DF; Frost JJ; Kuhar MJ; Wagner HN -
Autoradiographic localization of 5-HT1 receptors to human and canine basilar arteries.
Brain Res Volume: 310 Page(s): 193 - 196
09/17/1984 Authors: Peroutka SJ; Kuhar MJ -
Parkinson's disease: depletion of substantia nigra neurotensin receptors.
Brain Res Volume: 308 Page(s): 186 - 190
08/06/1984 Authors: Uhl GR; Whitehouse PJ; Price DL; Tourtelotte WW; Kuhar MJ -
Characterization of muscarinic cholinergic receptor binding in the vas deferens, bladder, prostate and penis of the rabbit.
J Urol Volume: 132 Page(s): 392 - 396
08/01/1984 Authors: Lepor H; Kuhar MJ -
Effects of postmortem delay and temperature on neurotransmitter receptor binding in a rat model of the human autopsy process.
J Neurochem Volume: 43 Page(s): 553 - 559
08/01/1984 Authors: Whitehouse PJ; Lynch D; Kuhar MJ -
Characterization and localization of the muscarinic cholinergic receptor in human prostatic tissue.
J Urol Volume: 132 Page(s): 397 - 402
08/01/1984 Authors: Lepor H; Kuhar MJ -
Dopamine receptors in the anterior lobe of the human pituitary gland: autoradiographic localization.
Brain Res Volume: 306 Page(s): 391 - 395
07/23/1984 Authors: De Souza EB; Kuhar MJ -
Corticotropin-releasing factor receptors in rat forebrain: autoradiographic identification.
Science Volume: 224 Page(s): 1449 - 1451
06/29/1984 Authors: De Souza EB; Perrin MH; Insel TR; Rivier J; Vale WW; Kuhar MJ -
Chronic neuroleptic treatment enhances neurotensin receptor binding in human and rat substantia nigra.
Nature Volume: 309 Page(s): 350 - 352
05/24/1984 Authors: Uhl GR; Kuhar MJ -
Corticotropin-releasing factor receptors in rat pituitary gland: autoradiographic localization.
Brain Res Volume: 296 Page(s): 202 - 207
03/26/1984 Authors: De Souza EB; Perrin MH; Rivier J; Vale WW; Kuhar MJ -
Distribution of muscarinic cholinergic high and low affinity agonist binding sites: a light microscopic autoradiographic study.
Brain Res Bull Volume: 12 Page(s): 233 - 243
03/01/1984 Authors: Wamsley JK; Zarbin MA; Kuhar MJ -
Distribution of alpha 2 agonist binding sites in the rat and human central nervous system: analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents.
Brain Res Volume: 319 Page(s): 69 - 101
03/01/1984 Authors: Unnerstall JR; Kopajtic TA; Kuhar MJ -
Anatomic localization of cholecystokinin receptors to the pyloric sphincter.
Am J Physiol Volume: 246 Page(s): R127 - R130
01/01/1984 Authors: Smith GT; Moran TH; Coyle JT; Kuhar MJ; O'Donahue TL; McHugh PR -
Mapping receptors for alpha 2-agonists in the central nervous system.
J Cardiovasc Pharmacol Volume: 6 Suppl 3 Page(s): S536 - S542
01/01/1984 Authors: Kuhar MJ; Unnerstall JR -
DOPAMINE-RECEPTORS IN THE ANTERIOR LOBE OF THE HUMAN PITUITARY-GLAND - AUTORADIOGRAPHIC LOCALIZATION
BRAIN RESEARCH Volume: 306 Page(s): 391 - 395
01/01/1984 Authors: DESOUZA EB; KUHAR MJ -
Distribution of
2 agonist binding sites in the rat and human central nervous system: Analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents
Brain Research Reviews Volume: 7 Page(s): 69 - 101
01/01/1984 Authors: Unnerstall JR; Kopajtic TA; Kuhar MJ -
AXONAL-TRANSPORT OF MUSCARINIC CHOLINERGIC RECEPTORS AND ITS IMPLICATIONS
TRENDS IN PHARMACOLOGICAL SCIENCES Page(s): 53 - 54
01/01/1984 Authors: KUHAR MJ; ZARBIN MA -
THE EFFECTS OF AGE ON DOPAMINE-RECEPTORS MEASURED BY POSITRON TOMOGRAPHY IN THE LIVING HUMAN-BRAIN
Volume: 25 Page(s): P73 - P73
01/01/1984 Authors: WONG DF; WAGNER HN; DANNALS RF; FROST JJ; RAVERT HV; LINKS JM; FOLSTEIN MF; JENSEN BA; KUHAR MJ; TOUNG JT -
EFFECTS OF AGE AND SEX ON DOPAMINE-RECEPTORS IN THE LIVING HUMAN-BRAIN
Volume: 16 Page(s): 128 - 128
01/01/1984 Authors: WONG DF; WAGNER HN; DANNALS RF; FROST JJ; RAVERT HT; LINKS JM; FOLSTEIN MF; JENSEN BA; KUHAR MJ; TOUNG JT -
Receptor autoradiography in brain: Coping with regional differences in autoradiographic efficiency with tritium
Federation Proceedings Volume: 43
01/01/1984 Authors: Unnerstall JR; Mashall RD; DeSouza EB; Kuhar MJ -
RECEPTORS IN THE NUCLEUS BASALIS OF PRIMATES - AN INVITRO AUTORADIOGRAPHIC STUDY
Volume: 16 Page(s): 118 - 118
01/01/1984 Authors: WHITEHOUSE PJ; JONES BE; KOPAJTIC TA; PRICE DL; KUHAR MJ -
Assessment of dopamine receptor densities in the human brain with carbon-11-labeled N-methylspiperone.
Ann Neurol Volume: 15 Suppl Page(s): S79 - S84
01/01/1984 Authors: Wagner HN; Burns HD; Dannals RF; Wong DF; Langstrm B; Duelfer T; Frost JJ; Ravert HT; Links JM; Rosenbloom SB -
IMAGING OPIATE RECEPTORS WITH POSITRON EMISSION TOMOGRAPHY
Volume: 25 Page(s): P73 - P73
01/01/1984 Authors: FROST JJ; DANNALS RF; RAVERT HT; WILSON AA; WONG DF; LINKS JM; BURNS HD; KUHAR MJ; SNYDER SH; WAGNER HN -
(3-N-[C-11]METHYL)SPIPERONE, A LIGAND-BINDING TO DOPAMINE-RECEPTORS - RADIOCHEMICAL SYNTHESIS AND BIODISTRIBUTION STUDIES IN MICE
JOURNAL OF NUCLEAR MEDICINE Volume: 25 Page(s): 1222 - 1227
01/01/1984 Authors: BURNS HD; DANNALS RF; LANGSTROM B; RAVERT HT; ZEMYAN SE; DUELFER T; WONG DF; FROST JJ; KUHAR MJ; WAGNER HN -
CANINE INHERITED ATAXIA - NEUROTRANSMITTER RECEPTORS IN THE CEREBELLUM
Volume: 16 Page(s): 135 - 135
01/01/1984 Authors: TRONCOSO JC; CORK LC; WHITEHOUSE PJ; KUHAR MJ; PRICE DL -
ANATOMIC LOCALIZATION OF CHOLECYSTOKININ RECEPTORS TO THE PYLORIC SPHINCTER
AMERICAN JOURNAL OF PHYSIOLOGY Volume: 246 Page(s): R127 - R130
01/01/1984 Authors: SMITH GT; MORAN TH; COYLE JT; KUHAR MJ; ODONAHUE TL; MCHUGH PR -
CORTICOTROPIN-RELEASING FACTOR RECEPTORS IN BRAIN - AUTORADIOGRAPHIC IDENTIFICATION
Volume: 41 Page(s): 1223 - 1223
01/01/1984 Authors: DESOUZA EB; INSEL TR; KUHAR MJ -
Normalization of spiroperidol binding in the denervated rat striatum by homologous grafts of substantia nigra.
Science Volume: 222 Page(s): 937 - 939
11/25/1983 Authors: Freed WJ; Ko GN; Niehoff DL; Kuhar MJ; Hoffer BJ; Olson L; Cannon-Spoor HE; Morihisa JM; Wyatt RJ -
Differential localization of type I and type II benzodiazepine binding sites in substantia nigra.
Nature Volume: 306 Page(s): 57 - 60
11/03/1983 Authors: Lo MM; Niehoff DL; Kuhar MJ; Snyder SH -
Benzodiazepine receptors: localization in rat amygdala.
J Neurosci Volume: 3 Page(s): 2091 - 2097
10/01/1983 Authors: Niehoff DL; Kuhar MJ -
Imaging dopamine receptors in the human brain by positron tomography.
Science Volume: 221 Page(s): 1264 - 1266
09/23/1983 Authors: Wagner HN; Burns HD; Dannals RF; Wong DF; Langstrom B; Duelfer T; Frost JJ; Ravert HT; Links JM; Rosenbloom SB -
Axonal transport of beta-adrenergic receptors. Antero- and retrogradely transported receptors differ in agonist affinity and nucleotide sensitivity.
Mol Pharmacol Volume: 24 Page(s): 341 - 348
09/01/1983 Authors: Zarbin MA; Palacios JM; Wamsley JK; Kuhar MJ -
Autoradiographic differentiation of multiple benzodiazepine receptors by detergent solubilization and pharmacologic specificity.
Neurosci Lett Volume: 39 Page(s): 37 - 44
08/19/1983 Authors: Lo MM; Niehoff DL; Kuhar MJ; Snyder SH -
Benzodiazepine receptors: preferential stimulation of Type 1 receptors by pentobarbital.
Eur J Pharmacol Volume: 92 Page(s): 131 - 134
08/19/1983 Authors: Niehoff DL; Mashal RD; Kuhar MJ -
Autoradiographic localization of beta-adrenoceptors in rat kidney.
Eur J Pharmacol Volume: 91 Page(s): 305 - 310
07/22/1983 Authors: Summers RJ; Kuhar MJ -
Amyotrophic lateral sclerosis: alterations in neurotransmitter receptors.
Ann Neurol Volume: 14 Page(s): 8 - 16
07/01/1983 Authors: Whitehouse PJ; Wamsley JK; Zarbin MA; Price DL; Tourtellotte WW; Kuhar MJ -
Adenosine receptors: autoradiographic evidence for their location on axon terminals of excitatory neurons.
Science Volume: 220 Page(s): 967 - 969
05/27/1983 Authors: Goodman RR; Kuhar MJ; Hester L; Snyder SH -
Ontogeny of opiate binding sites in the hippocampus, olfactory bulb and other regions of the rat forebrain by autoradiographic methods.
Brain Res Volume: 283 Page(s): 157 - 169
04/01/1983 Authors: Unnerstall JR; Molliver ME; Kuhar MJ; Palacios JM -
Autoradiographic localization of cholecystokinin receptors in rodent brain.
J Neurosci Volume: 3 Page(s): 877 - 906
04/01/1983 Authors: Zarbin MA; Innis RB; Wamsley JK; Snyder SH; Kuhar MJ -
Ontogeny of opiate binding sites in the hippocampus, olfactory bulb and other regions of the rat forebrain by autoradiographic methods.
Brain Research Volume: 283 Page(s): 157 - 169
04/01/1983 Authors: Unnerstall JR; Molliver ME; Kuhar MJ; Palacios JM -
Autoradiographic visualization of rat brain binding sites for bombesin-like peptides.
Eur J Pharmacol Volume: 87 Page(s): 163 - 164
01/28/1983 Authors: Wolf SS; Moody TW; O'Donohue TL; Zarbin MA; Kuhar MJ -
Distribution and physiological significance of opioid receptors in the brain.
Br Med Bull Volume: 39 Page(s): 47 - 52
01/01/1983 Authors: Atweh SF; Kuhar MJ -
I-125-ALPHA-BUNGAROTOXIN BINDING-SITES UNDERGO AXONAL-TRANSPORT IN RAT SCIATIC-NERVE
Volume: 42 Page(s): 1147 - 1147
01/01/1983 Authors: AIZENMAN E; MILLINGTON WR; ZARBIN MA; BIERKAMPER GG; KUHAR MJ -
CHANGES OF MOTOR NEURON CHOLINERGIC RECEPTORS AFTER AXOTOMY
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 42 Page(s): 313 - 313
01/01/1983 Authors: TRONCOSO JC; WHITEHOUSE PJ; KUHAR MJ; GRIFFIN JW; CORK LC; PRICE DL -
In vitro labeling receptor autoradiography: loss of label during ethanol dehydration and preparative procedures.
Brain Res Volume: 244 Page(s): 178 - 181
07/22/1982 Authors: Kuhar MJ; Unnerstall JR -
In ethanol
Brain Research Volume: 244 Page(s): 178 - 181
07/22/1982 Authors: Kuhar MJ; Unnerstall JR -
Effects of gamma-aminobutyric acid agonist and antagonist drugs on local cerebral glucose utilization.
J Neurosci Volume: 2 Page(s): 853 - 860
07/01/1982 Authors: Palacios JM; Kuhar MJ; Rapoport SI; London ED -
Axonal transport of muscarinic cholinergic receptors in rat vagus nerve: high and low affinity agonist receptors move in opposite directions and differ in nucleotide sensitivity.
J Neurosci Volume: 2 Page(s): 934 - 941
07/01/1982 Authors: Zarbin MA; Wamsley JK; Kuhar MJ -
Quantitative receptor autoradiography using [3H]ultrofilm: application to multiple benzodiazepine receptors.
J Neurosci Methods Volume: 6 Page(s): 59 - 73
07/01/1982 Authors: Unnerstall JR; Niehoff DL; Kuhar MJ; Palacios JM -
Receptors for clonidine in brain: insights into therapeutic actions.
J Clin Psychiatry Volume: 43 Page(s): 17 - 19
06/01/1982 Authors: Kuhar MJ -
Binding of a radiolabeled triazolopyridazine to a subtype of benzodiazepine receptor in the rat cerebellum.
J Pharmacol Exp Ther Volume: 221 Page(s): 670 - 675
06/01/1982 Authors: Niehoff DL; Mashal RD; Horst WD; O'Brien RA; Palacios JM; Kuhar MJ -
Distribution of opiate receptors in the monkey brain: an autoradiographic study.
Neuroscience Volume: 7 Page(s): 595 - 613
03/01/1982 Authors: Wamsley JK; Zarbin MA; Young WS; Kuhar MJ -
Beta adrenergic receptor localization in rat brain by light microscopic autoradiography.
Neurochem Int Volume: 4 Page(s): 473 - 490
01/01/1982 Authors: Palacios J; Kuhar MJ -
Peptide receptors undergo axonal transport in the rat vagus nerve.
Adv Biochem Psychopharmacol Volume: 33 Page(s): 463 - 470
01/01/1982 Authors: Zarbin MA; Wamsley JK; Kuhar MJ -
Specificity and potency of guanabenz at the alpha-2 adrenergic receptor
Federation Proceedings Volume: 41
01/01/1982 Authors: Unnerstall JR; Kopajtic TA; Deitch MW; Kuhar MJ -
LOSS OF DRUG AND NEUROTRANSMITTER RECEPTORS IN THE SPINAL-CORD OF PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS
Volume: 32 Page(s): A216 - A216
01/01/1982 Authors: WHITEHOUSE PJ; WAMSLEY JK; ZARBIN MA; PRICE DL; KUHAR MJ; DAVIS L; TOURTELLOTTE W -
RECEPTORS FOR CLONIDINE IN BRAIN - INSIGHTS INTO THERAPEUTIC ACTIONS
JOURNAL OF CLINICAL PSYCHIATRY Volume: 43 Page(s): 17 - 19
01/01/1982 Authors: KUHAR MJ -
CORRELATION OF INVITRO AND INVIVO BINDING OF SPIPERONE ANALOGS IN THE BRAIN
Volume: 23 Page(s): P22 - P22
01/01/1982 Authors: SCHEININ B; POGUN S; SCHEFFEL U; WAUD JM; DUELFER T; DANNALS RF; BURNS HD; CORLEY EG; KUHAR MJ; WAGNER HN -
INVITRO LABELING RECEPTOR AUTORADIOGRAPHY - LOSS OF LABEL DURING ETHANOL DEHYDRATION AND PREPARATIVE PROCEDURES
BRAIN RESEARCH Volume: 244 Page(s): 178 - 181
01/01/1982 Authors: KUHAR MJ; UNNERSTALL JR -
COMPUTER IMAGE-ANALYSIS IN NEURODEGENERATIVE DISORDERS
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 41 Page(s): 360 - 360
01/01/1982 Authors: WHITEHOUSE PJ; PRICE DL; HEDREEN JC; STRUBLE RG; CRISS TB; STERNER RE; KUHAR MJ -
Prediction of the in vivo pharmacokinetics of binding to CNS opiate receptors from parameters measured in vitro
Journal of Nuclear Medicine Volume: 23
01/01/1982 Authors: Frost JJ; Kuhar MJ; Wagner HN -
Receptors for clonidine in brain: Insights into therapeutic actions
Journal of Clinical Psychiatry Volume: 43 Page(s): 17 - 19
01/01/1982 Authors: Kuhar MJ -
Neurotensin receptors are located on dopamine-containing neurones in rat midbrain.
Nature Volume: 294 Page(s): 587 - 589
12/10/1981 Authors: Palacios JM; Kuhar MJ -
Autoradiographic localization of opioid receptors in the mammalian retina.
Neurosci Lett Volume: 27 Page(s): 19 - 24
11/18/1981 Authors: Wamsley JK; Palacios JM; Kuhar MJ -
Ontogeny of high-affinity GABA and benzodiazepine receptors in the rat cerebellum: an autoradiographic study.
Brain Res Volume: 254 Page(s): 531 - 539
11/01/1981 Authors: Palacios JM; Kuhar MJ -
High affinity GABA receptors-autoradiographic localization.
Brain Res Volume: 222 Page(s): 285 - 307
10/19/1981 Authors: Palacios JM; Wamsley JK; Kuhar MJ -
Receptor autoradiography with tritium-sensitive film: potential for computerized densitometry.
Neurosci Lett Volume: 25 Page(s): 101 - 105
09/01/1981 Authors: Palacios JM; Niehoff DL; Kuhar MJ -
Benzodiazepine receptors are coupled to a subpopulation of gamma-aminobutyric acid (GABA) receptors: evidence from a quantitative autoradiographic study.
J Pharmacol Exp Ther Volume: 218 Page(s): 797 - 804
09/01/1981 Authors: Unnerstall JR; Kuhar MJ; Niehoff DL; Palacios JM -
Cholecystokinin receptors: presence and axonal flow in the rat vagus nerve.
Life Sci Volume: 29 Page(s): 697 - 705
08/17/1981 Authors: Zarbin MA; Wamsley JK; Innis RB; Kuhar MJ -
Muscarinic cholinergic receptors flow in the sciatic nerve.
Brain Res Volume: 217 Page(s): 155 - 161
07/27/1981 Authors: Wamsley JK; Zarbin MA; Kuhar MJ -
Muscarinic cholinergic receptor localization in brain by electron microscopic autoradiography.
Brain Res Volume: 216 Page(s): 1 - 9
07/06/1981 Authors: Kuhar MJ; Taylor N; Wamsley JK; Hulme EC; Birdsall NJ -
GABA benzodiazepine and histamine-H1 receptors in the guinea pig cerebellum: effects of kainic acid injections studied by autoradiographic methods.
Brain Res Volume: 214 Page(s): 155 - 162
06/09/1981 Authors: Palacios JM; Wamsley JK; Kuhar MJ -
[3H]Spiperone binding sites in brain: autoradiographic localization of multiple receptors.
Brain Res Volume: 213 Page(s): 277 - 289
06/01/1981 Authors: Palacios JM; Niehoff DL; Kuhar MJ -
[3H]Spiperone binding sites in brain: autoradiographic localization of multiple receptors
Brain Research Volume: 213 Page(s): 277 - 289
06/01/1981 Authors: Palacios JM; Niehoff DL; Kuhar MJ -
Increases and decreases in local cerebral glucose utilization in response to GABA agonists.
Eur J Pharmacol Volume: 71 Page(s): 333 - 336
05/08/1981 Authors: Palacios JM; Kuhar MJ; Rapoport SI; London ED -
Autoradiographic localization of CCK receptors in guinea pig brain.
Eur J Pharmacol Volume: 71 Page(s): 349 - 350
05/08/1981 Authors: Zarbin MA; Innis RB; Wamsley JK; Snyder SH; Kuhar MJ -
Glycine receptor: light microscopic autoradiographic localization with [3H]strychnine.
J Neurosci Volume: 1 Page(s): 532 - 547
05/01/1981 Authors: Zarbin MA; Wamsley JK; Kuhar MJ -
Neurotensin receptor localization by light microscopic autoradiography in rat brain.
Brain Res Volume: 206 Page(s): 273 - 285
02/16/1981 Authors: Young WS; Kuhar MJ -
Autoradiographic localization of muscarinic cholinergic receptors in rat brainstem.
J Neurosci Volume: 1 Page(s): 176 - 191
02/01/1981 Authors: Wamsley JK; Lewis MS; Young WS; Kuhar MJ -
Multiple benzodiazepine receptor localization by light microscopic radiohistochemistry.
J Pharmacol Exp Ther Volume: 216 Page(s): 425 - 430
02/01/1981 Authors: Young WS; Niehoff D; Kuhar MJ; Beer B; Lippa AS -
Anatomical mapping of clonidine (alpha-2 noradrenergic) receptors in rat brain: relationship to function.
Prog Clin Biol Res Volume: 71 Page(s): 41 - 52
01/01/1981 Authors: Young WS; Kuhar MJ -
Autoradiographic determination of neurotransmitter receptor distributions in the cerebral and cerebellar cortices.
J Histochem Cytochem Volume: 29 Page(s): 125 - 135
01/01/1981 Authors: Wamsley JK; Palacios JM; Young WS; Kuhar MJ -
GABA and glycine receptors in rat brain: autoradiographic localization.
Adv Biochem Psychopharmacol Volume: 29 Page(s): 445 - 451
01/01/1981 Authors: Palacios JM; Wamsley JK; Zarbin MA; Kuhar MJ -
Radiohistochemical studies of benzodiazepine and GABA receptors and their interactions.
Adv Biochem Psychopharmacol Volume: 26 Page(s): 53 - 60
01/01/1981 Authors: Palacios JM; Unnerstall JR; Young WS; Kuhar MJ -
The distribution of histamine H1-receptors in the rat brain: an autoradiographic study.
Neuroscience Volume: 6 Page(s): 15 - 37
01/01/1981 Authors: Palacios JM; Wamsley JK; Kuhar MJ -
AUTORADIOGRAPHIC DETERMINATION OF NEUROTRANSMITTER RECEPTOR DISTRIBUTIONS IN THE CEREBRAL AND CEREBELLAR CORTICES
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY Volume: 29 Page(s): 125 - 135
01/01/1981 Authors: WAMSLEY JK; PALACIOS JM; YOUNG WS; KUHAR MJ -
[SPIPERONE-H-3 BINDING-SITES IN BRAIN - AUTORADIOGRAPHIC LOCALIZATION OF MULTIPLE RECEPTORS
BRAIN RESEARCH Volume: 213 Page(s): 277 - 289
01/01/1981 Authors: PALACIOS JM; NIEHOFF DL; KUHAR MJ -
Autoradiographic localization of drug and neurotransmitter receptors in the brain
Trends in Neurosciences Volume: 4 Page(s): 60 - 64
01/01/1981 Authors: Kuhar MJ -
RECEPTOR AUTORADIOGRAPHY WITH TRITIUM-SENSITIVE FILM - ANALYSIS BY COMPUTERIZED DENSITOMETRY
Volume: 29 Page(s): 894 - 894
01/01/1981 Authors: PALACIOS JM; KUHAR MJ -
SYNTHESIS OF RADIOTRACERS FOR INVIVO MAPPING AND QUANTIFICATION OF DOPAMINE-RECEPTORS
Volume: 22 Page(s): P12 - P13
01/01/1981 Authors: CORLEY EG; BURNS HD; FROST JJ; DUELFER T; KUHAR MJ; WAGNER HN -
Ontogeny of high-affinity GABA and benzodiazepine receptors in the rat cerebellum: An autoradiographic study
Developmental Brain Research Volume: 2 Page(s): 531 - 539
01/01/1981 Authors: Palacios JM; Kuhar MJ -
Benzodiazepine and GABA receptors. Autoradiographic studies
Neuroscience Letters Volume: 24
01/01/1981 Authors: Kuhar MJ; Palacios JM; Niehoff DL -
Autoradiographic determination of neurotransmitter receptor distributions in the cerebral and cerebellar cortices
Journal of Histochemistry and Cytochemistry Volume: 29 Page(s): 125 - 135
01/01/1981 Authors: Wamsley JK; Palacios JM; Young WS; Kuhar MJ -
INVITRO BINDING-STUDIES OF NEW BUTYROPHENONE ANALOGS DESIGNED TO INTERACT WITH DOPAMINE-RECEPTORS
Volume: 22 Page(s): P73 - P74
01/01/1981 Authors: POGUN S; WAUD J; BURNS HD; CORLEY EG; DUELFER T; DRANBAUER B; KUHAR M; WAGNER HN -
Autoradiographic Determination of Neurotransmitter Receptor Distributions in the Cerebral and Cerebellar Cortices 1 , 2.
J Histochem Cytochem Volume: 29 Page(s): 125 - 135
01/01/1981 Authors: Wamsley JK; Palacios JM; Young WS; Kuhar MJ -
alpha 2-Adrenergic receptors are associated with renal proximal tubules.
Eur J Pharmacol Volume: 67 Page(s): 493 - 495
10/31/1980 Authors: Young WS; Kuhar MJ -
Muscarinic cholinergic receptors: autoradiographic localization of high and low affinity agonist binding sites.
Brain Res Volume: 200 Page(s): 1 - 12
10/27/1980 Authors: Wamsley JK; Zarbin MA; Birdsall NJ; Kuhar MJ -
Opioid receptors undergo axonal flow.
Science Volume: 210 Page(s): 76 - 78
10/03/1980 Authors: Young WS; Wamsley JK; Zarbin MA; Kuhar MJ -
Differentiation of delta and mu opiate receptor localizations by light microscopic autoradiography.
Proc Natl Acad Sci U S A Volume: 77 Page(s): 6239 - 6243
10/01/1980 Authors: Goodman RR; Snyder SH; Kuhar MJ; Young WS -
Striatal opiate receptors: pre- and postsynaptic localization.
Life Sci Volume: 27 Page(s): 1175 - 1183
09/29/1980 Authors: Murrin LC; Coyle JT; Kuhar MJ -
Inhibition of high affinity choline uptake. Structure activity studies.
Biochem Pharmacol Volume: 29 Page(s): 2413 - 2416
09/15/1980 Authors: Batzold F; DeHaven R; Kuhar MJ; Birdsall N -
Beta-adrenergic-receptor localization by light microscopic autoradiography.
Science Volume: 208 Page(s): 1378 - 1380
06/20/1980 Authors: Palacios JM; Kuhar MJ -
Immunohistochemical localization of enkephalin in rat forebrain.
Brain Res Volume: 190 Page(s): 153 - 174
05/19/1980 Authors: Wamsley JK; Young WS; Kuhar MJ -
Autoradiographic localization of neuroleptic and dopamine receptors in the caudate-putamen and substantia nigra: Effects of lesions. L.C. Murrin, K. Gale and M.J. Kuhar European J. Pharmacol. 60 (1979) 229-235
European Journal of Pharmacology Volume: 62 Page(s): 353 - 354
04/04/1980 Authors: Murrin LC; Gale K; Kuhar MJ -
Serotonin receptor localization in rat brain by light microscopic autoradiography.
Eur J Pharmacol Volume: 62 Page(s): 237 - 239
03/21/1980 Authors: Young WS; Kuhar MJ -
Noradrenergic alpha 1 and alpha 2 receptors: light microscopic autoradiographic localization.
Proc Natl Acad Sci U S A Volume: 77 Page(s): 1696 - 1700
03/01/1980 Authors: Young WS; Kuhar MJ -
Ontogeny of muscarinic receptors in rat brain.
Brain Res Volume: 184 Page(s): 375 - 383
02/24/1980 Authors: Kuhar MJ; Birdsall NJ; Burgen AS; Hulme EC -
Radiohistochemical localization of benzodiazepine receptors in rat brain.
J Pharmacol Exp Ther Volume: 212 Page(s): 337 - 346
02/01/1980 Authors: Young WS; Kuhar MJ -
Anatomical localization of enkephalin immunoreactive sites in rat forebrain.
Adv Biochem Psychopharmacol Volume: 22 Page(s): 257 - 270
01/01/1980 Authors: Wamsley JK; Young WS; Kuhar MJ -
The benzodiazepine receptor: anatomical aspects.
NIDA Res Monogr Page(s): 12 - 21
01/01/1980 Authors: Kuhar MJ -
Histochemistry of receptors.
Adv Biochem Psychopharmacol Volume: 21 Page(s): 51 - 56
01/01/1980 Authors: Young WS; Palacios JM; Kuhar MJ -
Autoradiographic localization of gamma-aminobutyric acid (GABA) receptors in the rat cerebellum.
Proc Natl Acad Sci U S A Volume: 77 Page(s): 670 - 674
01/01/1980 Authors: Palacios JM; Young WS; Kuhar MJ -
Radiohistochemical localization of insulin receptors in the adult and developing rat brain
Neuropeptides Volume: 1 Page(s): 15 - 22
01/01/1980 Authors: Young WS; Kuhar MJ; Roth J; Brownstein MJ -
Radiohistochemical localization of GABA receptors
Brain Research Bulletin Volume: 5 Page(s): 145 - 148
01/01/1980 Authors: Palacios JM; Kuhar MJ -
LOCALIZATION OF BETA-ADRENERGIC RECEPTORS IN RAT-BRAIN BY LIGHT MICROSCOPIC AUTORADIOGRAPHY
Volume: 39 Page(s): 593 - 593
01/01/1980 Authors: PALACIOS JM; DEHAVEN RN; KUHAR MJ -
NORADRENERGIC ALPHA-1 AND ALPHA-2 RECEPTORS - LIGHT MICROSCOPIC AUTORADIOGRAPHIC LOCALIZATION
Volume: 39 Page(s): 593 - 593
01/01/1980 Authors: YOUNG WS; KUHAR MJ -
Differentiation of delta and mu opiate receptor localizations by light microscopic autoradiography
Proceedings of the National Academy of Sciences of the United States of America Volume: 77 Page(s): 6239 - 6243
01/01/1980 Authors: Goodman RR; Snyder SH; Kuhar MJ; Young WS -
Noradrenergic 1 and 2 receptors: Light microscopic autoradiographic localization
Proceedings of the National Academy of Sciences of the United States of America Volume: 77 Page(s): 1696 - 1700
01/01/1980 Authors: Young WS; Kuhar MJ -
A new method for receptor autoradiography: [3H]opioid receptors in rat brain.
Brain Res Volume: 179 Page(s): 255 - 270
12/28/1979 Authors: Young WS; Kuhar MJ -
Ontogeny of GABA and benzodiazepine receptors: effects of Triton X-100, bromide and muscimol.
Brain Res Volume: 179 Page(s): 390 - 395
12/28/1979 Authors: Palacios JM; Niehoff DL; Kuhar MJ -
Autoradiographic localization of neuroleptic and dopamine receptors in the caudate-putamen and substantia nigra: effects of lesions.
Eur J Pharmacol Volume: 60 Page(s): 229 - 235
12/07/1979 Authors: Murrin LC; Gale K; Kuhar MJ -
Autoradiographic localisation of benzodiazepine receptors in the brains of humans and animals [11]
Nature Volume: 280 Page(s): 393 - 395
12/01/1979 Authors: Young WS; Kuhar MJ -
Dompamine receptors in the rat frontal cortex: an autoradiographic study.
Brain Res Volume: 177 Page(s): 279 - 285
11/16/1979 Authors: Murrin LC; Kuhar MJ -
Noradrenergic alpha 1 and alpha 2 receptors: autoradiographic visualization.
Eur J Pharmacol Volume: 59 Page(s): 317 - 319
11/16/1979 Authors: Young WS; Kuhar MJ -
Dopamine receptors in the rat frontal cortex: An autoradiographic study
Brain Research Volume: 177 Page(s): 279 - 285
11/16/1979 Authors: Charles Murrin L; Kuhar MJ -
Choline: binding studies provide some evidence for a weak, direct agonist action in brain.
Mol Pharmacol Volume: 16 Page(s): 1084 - 1088
11/01/1979 Authors: Palacios JM; Kuhar MJ -
Neurotensin receptors: autoradiographic localization in rat CNS.
Eur J Pharmacol Volume: 59 Page(s): 161 - 163
10/26/1979 Authors: Young WS; Kuhar MJ -
Autoradiographic localization of H1-histamine receptors in brain using 3H-mepyramine: preliminary studies.
Eur J Pharmacol Volume: 58 Page(s): 295 - 304
10/01/1979 Authors: Palacios JM; Young WS; Kuhar MJ -
In vivo receptor binding: attempts to improve specific/non-specific ratios.
Life Sci Volume: 25 Page(s): 819 - 826
09/03/1979 Authors: Niehoff DL; Palacios JM; Kuhar MJ -
Autoradiographic localisation of benzodiazepine receptors in the brains of humans and animals.
Nature Volume: 280 Page(s): 391 - 394
08/02/1979 Authors: Young WS; Kuhar MJ -
Neuroleptic and dopamine receptors: autoradiographic localization of [3H]spiperone in rat brain.
Brain Res Volume: 169 Page(s): 1 - 9
06/15/1979 Authors: Klemm N; Murrin LC; Kuhar MJ -
Post-mortem changes in high affinity choline uptake.
J Neurochem Volume: 32 Page(s): 1487 - 1494
05/01/1979 Authors: Klemm N; Kuhar MJ -
Immunohistochemical mapping of enkephalin containing cell bodies, fibers and nerve terminals in the brain stem of the rat.
Brain Res Volume: 166 Page(s): 75 - 94
04/20/1979 Authors: Uhl GR; Goodman RR; Kuhar MJ; Childers SR; Snyder SH -
Sodium-dependent high affinity choline uptake.
Prog Brain Res Volume: 49 Page(s): 71 - 76
01/01/1979 Authors: Kuhar MJ -
Autoradiographic localization of [3H]gentamicin in the proximal renal tubules of mice.
Antimicrob Agents Chemother Volume: 15 Page(s): 131 - 133
01/01/1979 Authors: Kuhar MJ; Mak LL; Lietman PS -
Histochemical localization of opiate receptors and the enkephalins.
Adv Biochem Psychopharmacol Volume: 20 Page(s): 53 - 68
01/01/1979 Authors: Kuhar MJ; Uhl GR -
RADIO-HISTOCHEMICAL STUDIES OF THE GABA AND BENZODIAZEPINE (BZ) RECEPTORS
BRAIN RESEARCH BULLETIN Volume: 4 Page(s): 700 - 700
01/01/1979 Authors: KUHAR MJ; PALACIOS JM; YOUNG WS -
INVIVO RECEPTOR-BINDING - ATTEMPTS TO IMPROVE SPECIFIC-NON-SPECIFIC RATIOS
LIFE SCIENCES Volume: 25 Page(s): 819 - 826
01/01/1979 Authors: NIEHOFF DL; PALACIOS JM; KUHAR MJ -
AUTO-RADIOGRAPHY OF OPIATE AND BENZODIAZEPINE RECEPTORS - INVITRO LABELING OF TISSUE-SECTIONS
Volume: 38 Page(s): 687 - 687
01/01/1979 Authors: YOUNG WS; KUHAR MJ -
AUTORADIOGRAPHIC LOCALIZATION OF HISTAMINE H1-RECEPTORS IN BRAIN
Volume: 38 Page(s): 261 - 261
01/01/1979 Authors: PALACIOS JM; YOUNG WS; KUHAR MJ -
Psychotropic drugs and central cholinergic mechanisms
Psychopharmacology Bulletin Volume: 15 Page(s): 75 - 76
01/01/1979 Authors: Kuhar MJ -
Autoradiography of opiate and benzodiazepine receptors: in vitro labeling of tissue sections
Federation Proceedings Volume: 38
01/01/1979 Authors: Young WS; Kuhar MJ -
In situ injection of kainic acid: a new method for selectively lesioning neural cell bodies while sparing axons of passage.
J Comp Neurol Volume: 180 Page(s): 301 - 323
07/15/1978 Authors: Coyle JT; Molliver ME; Kuhar MJ -
Iontophoresis of neurotensin in the area of the locus coeruleus.
Brain Res Volume: 150 Page(s): 431 - 435
07/14/1978 Authors: Young WS; Uhl GR; Kuhar MJ -
Synaptosomal transport: a chloride dependence for choline, GABA, glycine and several other compounds.
J Neurochem Volume: 31 Page(s): 251 - 256
07/01/1978 Authors: Kuhar MJ; Zarbin MA -
Enkephalin-containing pathway: amygdaloid efferents in the stria terminalis.
Brain Res Volume: 149 Page(s): 223 - 228
06/23/1978 Authors: Uhl GR; Kuhar MJ; Synder SH -
Amino acid transport: alterations due to synaptosomal depolarization.
Life Sci Volume: 22 Page(s): 2009 - 2016
06/12/1978 Authors: Murrin LC; Lewis MS; Kuhar MJ -
Histochemical localization of opiate receptors and opioid peptides.
Fed Proc Volume: 37 Page(s): 153 - 157
02/01/1978 Authors: Kuhar MJ -
Enkephalin and neurotensin: immunohistochemical localization and identification of an amygdalofugal pathway.
Adv Biochem Psychopharmacol Volume: 18 Page(s): 71 - 87
01/01/1978 Authors: Uhl GR; Goodman RR; Kuhar MJ; Snyder SH -
Dopamine receptor binding in vivo: the feasibility of autoradiographic studies.
Life Sci Volume: 22 Page(s): 203 - 210
01/01/1978 Authors: Kuhar MJ; Murrin LC; Malouf AT; Klemm N -
Sodium-dependent, high affinity choline uptake.
J Neurochem Volume: 30 Page(s): 15 - 21
01/01/1978 Authors: Kuhar MJ; Murrin LC -
Opiate receptors: some anatomical and physiological aspects.
Ann N Y Acad Sci Volume: 311 Page(s): 35 - 48
01/01/1978 Authors: Kuhar MJ -
Presynaptic localization of opiate receptors in the vagal and accessory optic systems: an autoradiographic study.
Neuropharmacology Volume: 17 Page(s): 65 - 71
01/01/1978 Authors: Atweh SF; Murrin LC; Kuhar MJ -
Effects of lesions on striatal opiate receptors
Federation Proceedings Volume: 37
01/01/1978 Authors: Murrin LC; Coyle JT; Kuhar MJ -
Autoradiographic localization of [3H]reserpine binding sites in rat brain.
J Pharmacol Exp Ther Volume: 203 Page(s): 564 - 574
12/01/1977 Authors: Murrin LC; Enna SJ; Kuhar MJ -
Autoradiographic localization of opiate receptors in rat brain. III. The telencephalon.
Brain Res Volume: 134 Page(s): 393 - 405
10/14/1977 Authors: Atweh SF; Kuhar MJ -
On the relationship between (3H)choline uptake activation and (3H)acetylcholine release.
J Neurochem Volume: 29 Page(s): 681 - 687
10/01/1977 Authors: Murrin LC; DeHaven RN; Kuhar MJ -
Neurotensin: immunohistochemical localization in rat central nervous system.
Proc Natl Acad Sci U S A Volume: 74 Page(s): 4059 - 4063
09/01/1977 Authors: Uhl GR; Kuhar MJ; Snyder SH -
Iontophoresis of methionine-enkephalin in the locus coeruleus area.
Brain Res Volume: 129 Page(s): 366 - 370
07/01/1977 Authors: Young WS; Bird SJ; Kuhar MJ -
Autoradiographic localization of opiate receptors in rat brain. II. The brain stem.
Brain Res Volume: 129 Page(s): 1 - 12
06/24/1977 Authors: Atweh SF; Kuhar MJ -
Opioid peptide enkephalin: immunohistochemical mapping in rat central nervous system.
Proc Natl Acad Sci U S A Volume: 74 Page(s): 2167 - 2171
05/01/1977 Authors: Simantov R; Kuhar MJ; Uhl GR; Snyder SH -
Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla.
Brain Res Volume: 124 Page(s): 53 - 67
03/18/1977 Authors: Atweh SF; Kuhar MJ -
Iontophoretic application of opiates to the locus coeruleus.
Brain Res Volume: 122 Page(s): 523 - 533
02/25/1977 Authors: Bird SJ; Kuhar MJ -
Autoradiographic localization of receptor sites in the CNS in vivo
Acta Pharmacologica et Toxicologica Volume: 41 Page(s): 100 - 101
01/01/1977 Authors: Kuhar MJ -
NEUROTENSIN - IMMUNOHISTOCHEMICAL LOCALIZATION IN RAT CENTRAL NERVOUS-SYSTEM - (AMYGDALA-SUBSTANTIA GELATINOSA-PITUITARY-PEPTIDE-HYPOTHALAMUS)
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume: 74 Page(s): 4059 - 4063
01/01/1977 Authors: UHL GR; KUHAR MJ; SNYDER SH -
Opioid peptide enkephalin: immunohistochemical mapping in rat central nervous system
Proceedings of the National Academy of Sciences of the United States of America Volume: 75 Page(s): 2167 - 2171
01/01/1977 Authors: Simantov R; Kuhar MJ; Uhi GR; Snyder SH -
Activation of high-affinity choline uptake in vitro by depolarizing agents.
Mol Pharmacol Volume: 12 Page(s): 1082 - 1090
11/01/1976 Authors: Murrin LC; Kuhar MJ -
Opiate receptor: autoradiographic localization in rat brain.
Proc Natl Acad Sci U S A Volume: 73 Page(s): 3729 - 3733
10/01/1976 Authors: Pert CB; Kuhar MJ; Snyder SH -
Localization of cholinergic muscarinic receptors in rat brain by light microscopic radioautography.
Brain Res Volume: 110 Page(s): 229 - 243
07/09/1976 Authors: Kuhar M; Yamamura HI -
High affinity choline uptake: ionic and energy requirements.
J Neurochem Volume: 27 Page(s): 93 - 99
07/01/1976 Authors: Simon JR; Kuhar MJ -
Effects of anesthetics and septal lesions and stimulation on 3H-acetylcholine formation in rat hippocampus.
Eur J Pharmacol Volume: 37 Page(s): 311 - 319
06/01/1976 Authors: Atweh SF; Kuhar MJ -
Sodium-dependent high affinity choline uptake: a regulatory step in the synthesis of acetylcholine.
J Neurochem Volume: 26 Page(s): 909 - 922
05/01/1976 Authors: Simon JR; Atweh S; Kuhar MJ -
The regional distribution of a morphine-like factors enkephalin in monkey brain.
Brain Res Volume: 106 Page(s): 189 - 197
04/16/1976 Authors: Simantov R; Kuhar MJ; Pasternak GW; Snyder SH -
Binding of [3H] kainic acid, and analogue of Lglutamate, to brain membranes.
J Neurochem Volume: 26 Page(s): 141 - 147
01/01/1976 Authors: Simon JR; Contrera JF; Kuhar MJ -
The action of opiates at autoradiographically identified opiate receptor sites: a microiontophoretic study
Federation Proceedings Volume: 35
01/01/1976 Authors: Bird SJ; Kuhar MJ -
Serotonergic synaptosomes from rat hippocampus: lack of acetylcholinesterase.
Brain Res Volume: 99 Page(s): 415 - 418
12/05/1975 Authors: Kuhar MJ; Simon JR; Taylor N -
Utilization of sodium-dependent high affinity choline uptake in vitro as a measure of the activity of cholinergic neurons in vivo.
Life Sci Volume: 17 Page(s): 1535 - 1544
11/15/1975 Authors: Atweh S; Simon JR; Kuhar MJ -
Further evidence for cholinergic habenulo-interpeduncular neurons: pharmacologic and functional characteristics.
Brain Res Volume: 97 Page(s): 265 - 275
10/31/1975 Authors: Kuhar MJ; DeHaven RN; Yamamura HI; Rommel-Spacher H; Simon JR -
Biochemical indentification of the mammalian muscarinic cholinergic receptor.
Fed Proc Volume: 34 Page(s): 1915 - 1921
09/01/1975 Authors: Snyder SH; Chang KJ; Kuhar MJ; Yamamura HI -
Regional distribution of postsynaptic receptor binding for gamma-aminobutyric acid (GABA) in monkey brain.
Brain Res Volume: 93 Page(s): 168 - 174
07/25/1975 Authors: Enna SJ; Kuhar MJ; Snyder SH -
Autoradiograhic localization of the opiate receptor in rat brain.
Life Sci Volume: 16 Page(s): 1849 - 1853
06/15/1975 Authors: Pert CB; Kuhar MJ; Snyder SH -
Inhibition of synaptosomal uptake of choline by various choline analogs.
Biochem Pharmacol Volume: 24 Page(s): 1139 - 1142
05/15/1975 Authors: Simon JR; Mittag TW; Kuhar JM -
Impulse-flow regulation of high affinity choline uptake in brain cholinergic nerve terminals.
Nature Volume: 255 Page(s): 162 - 163
05/08/1975 Authors: Simon JR; Kuhar MG -
Effects of drugs and axotomy on acetylcholine levels in central cholinergic neurons
Naunyn-Schmiedeberg's Archives of Pharmacology Volume: 291 Page(s): 17 - 21
03/01/1975 Authors: Rommelspacher H; Kuhar MJ -
Light autoradiographic localisation of cholinergic muscarinic receptors in rat brain by specific binding of a potent antagonist.
Nature Volume: 253 Page(s): 560 - 561
02/13/1975 Authors: Kuhar MJ; Yamamura HI -
Association of serotonin-binding protein with projections of the midbrain raphe nuclei
Brain Research Volume: 83 Page(s): 169 - 172
01/03/1975 Authors: Tamir H; Kuhar MJ -
Effects of drugs and axotomy on acetylcholine levels in central cholinergic neurons.
Naunyn Schmiedebergs Arch Pharmacol Volume: 291 Page(s): 17 - 21
01/01/1975 Authors: Rommelspacher H; Kuhar MJ -
D & L amphetamine stereoisomers: comparative potencies in affecting the firing of central dopaminergic and noradrenergic neurons.
Psychopharmacol Commun Volume: 1 Page(s): 177 - 190
01/01/1975 Authors: Bunney BS; Walters JR; Kuhar MJ; Roth RH; Aghajanian GK -
Effects of dopaminergic drugs and acute medial forebrain bundle lesions on striatal acetylcholine levels.
Life Sci Volume: 16 Page(s): 65 - 70
01/01/1975 Authors: Rommelspacher H; Kuhar MJ -
Proceedings: Effect of drugs on alterations of neuronal impulse flow of a central cholinergic tract.
Naunyn Schmiedebergs Arch Pharmacol Volume: 287 Suppl Page(s): R10
01/01/1975 Authors: Rommelspacher H; Kuhar MJ -
Effect of drugs on alterations of neuronal impulse flow of a central cholinergic tract
NAUNYN-SCHMIED.ARCH.PHARM. Volume: 287
01/01/1975 Authors: Rommelspacher H; Kuhar MJ -
ATTEMPTS AT IDENTIFYING GLUTAMATE RECEPTOR IN BRAIN-TISSUE BY BINDING RADIOLABELED KAINIC ACID
Volume: 34 Page(s): 294 - 294
01/01/1975 Authors: SIMON JR; KUHAR MJ -
Effects of impulse flow alterations on the in vivo synthesis of 3H acetylcholine in the rat hippocampus
Pharmacologist Volume: 17
01/01/1975 Authors: Atweh S; Kuhar MJ -
CHOLINERGIC MUSCARINIC RECEPTOR - BIOCHEMICAL AND LIGHT AUTORADIOGRAPHIC LOCALIZATION IN BRAIN
CROATICA CHEMICA ACTA Volume: 47 Page(s): 475 - 488
01/01/1975 Authors: YAMAMURA HI; CHANG KJ; KUHAR MJ; SNYDER SH -
Sodium dependent high affinity choline uptake as a regulatory step in acetylcholine synthesis
Pharmacologist Volume: 17
01/01/1975 Authors: Simon JR; Kuhar MJ -
Effects of electrical stimulation on acetylcholine levels in central cholinergic nerve terminals.
Brain Res Volume: 81 Page(s): 243 - 251
12/06/1974 Authors: Rommelspacher H; Kuhar MJ -
The binding of vinblastine to tubulin and to particulate fractions of mammalian brain.
Cancer Res Volume: 34 Page(s): 3180 - 3186
12/01/1974 Authors: Owellen RJ; Donigian DW; Hartke CA; Dickerson RM; Kuhar MJ -
In vivo identification of muscarinic cholinergic receptor binding in rat brain.
Brain Res Volume: 80 Page(s): 170 - 176
11/08/1974 Authors: Yamamura HI; Kuhar MJ; Snyder SH -
Action of hemicholinium-3 on cholinergic nerve terminals after alteration of neuronal impulse flow.
Neuropharmacology Volume: 13 Page(s): 1015 - 1023
11/01/1974 Authors: Rommelspacher H; Goldberg AM; Kuhar MJ -
Brain histamine alterations after hypothalamic isolation.
Brain Res Volume: 78 Page(s): 144 - 151
09/20/1974 Authors: Dismukes K; Kuhar MJ; Snyder SH -
Acetylcholinesterase-staining synaptosomes from rat hippocampus: relative frequency and tentative estimation of internal concentration of free or 'labile bound' acetylcholine.
Brain Res Volume: 77 Page(s): 85 - 96
08/30/1974 Authors: Kuhar MJ; Rommelspacher H -
The subsynaptosomal localization of histamine, histidine decarboxylase and histamine methyltransferase in rat hypothalamus.
J Neurochem Volume: 23 Page(s): 37 - 45
07/01/1974 Authors: Snyder SH; Brown B; Kuhar MJ -
Acetylcholine uptake: lack of association with cholinergic neurons.
J Neurochem Volume: 22 Page(s): 1135 - 1137
06/01/1974 Authors: Kuhar MJ; Simon JR -
Release of acetylcholine from hippocampal slices by potassium depolarization: dependence on high affinity choline uptake.
Brain Res Volume: 70 Page(s): 372 - 376
04/19/1974 Authors: Mulder AH; Yamamura HI; Kuhar MJ; Snyder SH -
Muscarinic cholinergic receptor binding: regional distribution in monkey brain
Brain Research Volume: 66 Page(s): 541 - 546
02/08/1974 Authors: Yamamura HI; Kuhar MJ; Greenberg D; Snyder SH -
Subcellular localization of dopamine beta-hydroxylase and endogenous norepinephrine in the rat hypothalamus.
Brain Res Volume: 65 Page(s): 475 - 487
01/18/1974 Authors: Coyle JT; Kuhar MJ -
Serotonin neurons: a synaptic mechanism for the reuptake of serotonin.
Adv Biochem Psychopharmacol Volume: 10 Page(s): 287 - 295
01/01/1974 Authors: Kuhar MJ; Aghajanian GK; Roth RH -
Identification in vivo of muscarinic cholinergic receptor binding in rat brain
Pharmacologist Volume: 16
01/01/1974 Authors: Yamamura HI; Kuhar MJ; Snyder SH -
Muscarinic cholinergic receptor binding in mammalian central and peripheral nervous system: demonstration in vitro and in vivo
TRANS.AMER.SOC.NEUROCHEM. Volume: 5
01/01/1974 Authors: Yamamura HI; Kuhar MJ; Snyder SH -
Effects of lesions on the action of hemicholinium 3 (HC 3) on acetylcholine levels in rat brain
Federation Proceedings Volume: 33 Page(s): 1661
01/01/1974 Authors: Rommelspacher H; Kuhar MJ -
Inhibition of choline uptake into synaptosomes by choline analogues
Pharmacologist Volume: 16
01/01/1974 Authors: Simon JR; Kuhar MJ -
Neurotransmitter uptake: a tool in identifying neurotransmitter-specific pathways.
Life Sci Volume: 13 Page(s): 1623 - 1634
12/16/1973 Authors: Kuhar MJ -
Regional distribution of opiate receptor binding in monkey and human brain.
Nature Volume: 245 Page(s): 447 - 450
10/26/1973 Authors: Kuhar MJ; Pert CB; Snyder SH -
Choline and acetylcholine: regional distribution and effect of degeneration of cholinergic nerve terminals in the rat hippocampus.
Neuropharmacology Volume: 12 Page(s): 819 - 823
09/01/1973 Authors: Sethy VH; Roth RH; Kuhar MJ; Van Woert MH -
Cholinergic neurons: effect of acute septal lesion on acetylcholine and choline content of rat hippocampus.
Brain Res Volume: 55 Page(s): 481 - 484
06/15/1973 Authors: Sethy VH; Kuhar MJ; Roth RH; Van Woert MH; Aghajanian GK -
Serotonin-containing neuronal perikarya and terminals: differential effects of P-chlorophenylalanine.
Brain Res Volume: 54 Page(s): 85 - 101
05/17/1973 Authors: Aghajanian GK; Kuhar MJ; Roth RH -
Selective accumulation of 3 H-serotonin by nerve terminals of raphe neurones: an autoradiographic study.
Nat New Biol Volume: 241 Page(s): 187 - 189
02/07/1973 Authors: Kuhar MJ; Aghajanian GK -
Choline: selective accumulation by central cholinergic neurons.
J Neurochem Volume: 20 Page(s): 581 - 593
02/01/1973 Authors: Kuhar MJ; Sethy VH; Roth RH; Aghajanian GK -
Effect of gamma-hydroxybutyrate and gamma-butyrolactone on dopamine synthesis and uptake by rat striatum.
Biochem Pharmacol Volume: 21 Page(s): 2649 - 2652
10/01/1972 Authors: Bustos G; Kuhar MJ; Roth RH -
Tryptophan hydroxylase activity and synaptosomal uptake of serotonin in discrete brain regions after midbrain raphe lesions: correlations with serotonin levels and histochemical fluorescence.
Brain Res Volume: 44 Page(s): 165 - 176
09/15/1972 Authors: Kuhar MJ; Aghajanian GK; Roth RH -
Synthesis of catecholamines in the locus coeruleus from 3 H-tyrosine in vivo.
Biochem Pharmacol Volume: 21 Page(s): 2280 - 2282
08/15/1972 Authors: Kuhar MJ; Roth RH; Aghajanian GK -
Synaptosomes from forebrains of rats with midbrain raphe lesions: selective reduction of serotonin uptake.
J Pharmacol Exp Ther Volume: 181 Page(s): 36 - 45
04/01/1972 Authors: Kuhar MJ; Roth RH; Aghajanian GK -
Selective reduction of tryptophan hydroxylase activity in rat forebrain after midbrain raphe lesions.
Brain Res Volume: 35 Page(s): 167 - 176
12/10/1971 Authors: Kuhar MJ; Roth RH; Aghajanian GK -
The subcellular localization of histamine and histamine methyltransferase in rat brain.
J Neurochem Volume: 18 Page(s): 1515 - 1527
08/01/1971 Authors: Kuhar MJ; Taylor KM; Snyder SH -
A unique synaptosomal fraction, which accumulates glutamic and aspartic acids, in brain tissue.
Proc Natl Acad Sci U S A Volume: 68 Page(s): 1102 - 1106
06/01/1971 Authors: Wofsey AR; Kuhar MJ; Snyder SH -
The subcellular distribution of endogenous and exogenous serotonin in brain tissue: comparison of synaptosomes storing serotonin, norepinephrine, and gamma-aminobutyric acid.
J Neurochem Volume: 18 Page(s): 333 - 343
03/01/1971 Authors: Kuhar MJ; Shaskan EG; Snyder SH -
A possible mechanism for the pathogenic action of monosodium glutamate.
Res Commun Chem Pathol Pharmacol Volume: 2 Page(s): 95 - 97
01/01/1971 Authors: Kuhar MJ -
Neurotransmitter-specific synaptosomes in rat corpus striatum: morphological variations.
Proc Natl Acad Sci U S A Volume: 68 Page(s): 155 - 159
01/01/1971 Authors: Gfeller E; Kuhar MJ; Snyder SH -
Separation of synaptosomes storing catecholamines and gamma-aminobutyric acid in rat corpus striatum.
Brain Res Volume: 21 Page(s): 405 - 417
07/29/1970 Authors: Kuhar MJ; Green AI; Snyder SH; Gfeller E -
The subcellular distribution of free H3-glutamic acid in rat cerebral cortical slices.
J Pharmacol Exp Ther Volume: 171 Page(s): 141 - 152
01/01/1970 Authors: Kuhar MJ; Snyder SH -
Uptake and subcellular localization of neurotransmitters in the brain
International Review of Neurobiology Volume: 13 Page(s): 127 - 158
01/01/1970 Authors: Snyder SH; Kuhar MJ; Green AI; Coyle JT; Shaskan EG