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Profile

Paul Iuvone PhD

  • Department of Ophthalmology
    Professor
  • (404) 727-5989
  • miuvone@emory.edu
Head shot of Paul Iuvone

Overview

P. Michael Iuvone is vice director of research at the Emory Eye Center. Originally from New York, Dr. Iuvone came to Emory in 1978, serving in the pharmacology department, and was promoted to full professor in 1990. He held a joint appointment in ophthalmology from 1980.

Iuvone is a leader in numerous research organizations, such as the Association for Research in Vision and Ophthalmology (ARVO) and the International Society of Eye Research. He currently serves as principal investigator on a NIH grant that deals with retinal function, which provides basic science information relevant to eye diseases such as retinopathy of prematurity and diabetic retinopathy.

He is also co-investigator of a training grant from the National Eye Institute (NEI) and of an NEI core grant, that supports research of vision scientists in the Atlanta Vision Research Community, with laboratories at Emory University, the Atlanta VA Medical Center, Georgia Institute of Technology, Georgia State University, and Morehouse School of Medicine. He is a co-investigator on several other NIH grants dealing with myopia, retinal pathology, and circadian rhythms in health and disease.

National Recognition
He has been an editorial board member on five distinguished journals including the Experimental Eye Research and Molecular Vision. He was named a fellow of ARVO at the 2009 meeting. He has published more than 165 articles in peer-reviewed literature.

In 2014, Iuvone published The Retina and Circadian Rhythms (Springer, 2014), along with fellow editors Gianluca Tosini (Morehouse School of Medicine); Douglas G. McMahon (Vanderbilt University); and Shaun P. Collin (University of Western Australia). The book provides a comprehensive review of the retinal circadian rhythms and their roles in photoreception and visual function.

Academic Appointment

  • Professor, Department of Ophthalmology, Emory University School of Medicine
  • Professor, Department of Pharmacology, Emory University School of Medicine
  • Collaborating Scientist, Emory National Primate Center

Education

Degrees

  • Doctor of Philosophy from University of Florida
  • Bachelor of Science from University of Florida
  • Associate of Arts from University of Florida

Research

Publications

  • Conditional Knockouts of Interphotoreceptor Retinoid Binding Protein Suggest Two Independent Mechanisms for Retinal Degeneration and Myopia.
    Invest Ophthalmol Vis Sci Volume: 65 Page(s): 32
    06/03/2024 Authors: Getz TE; Chrenek MA; Papania JT; Shelton DA; Markand S; Iuvone PM; Kozmik Z; Boatright JH; Nickerson JM
  • Diurnal retinal and choroidal gene expression patterns support a role for circadian biology in myopia pathogenesis.
    Sci Rep Volume: 14 Page(s): 533
    01/04/2024 Authors: Stone RA; Tobias JW; Wei W; Schug J; Wang X; Zhang L; Iuvone PM; Nickla DL
  • Diurnal gene expression patterns in retina and choroid distinguish myopia progression from myopia onset.
    PLoS One Volume: 19 Page(s): e0307091
    01/01/2024 Authors: Stone RA; Tobias JW; Wei W; Carlstedt X; Zhang L; Iuvone PM; Nickla DL
  • Knocking out Stat3 in rod photoreceptor cells unexpectedly protects against light-induced retinal degeneration
    Volume: 64
    06/01/2023 Authors: Sellers J; Chrenek M; Garcia M; Still A; Iuvone P; Nickerson J; Boatright J
  • Deletion of histone demethylase Lsd1 (Kdm1a) during retinal development leads to defects in retinal function and structure.
    Front Cell Neurosci Volume: 17 Page(s): 1104592
    01/01/2023 Authors: Ferdous S; Shelton DA; Getz TE; Chrenek MA; L'Hernault N; Sellers JT; Summers VR; Iuvone PM; Boss JM; Boatright JH
  • Diabetic rats with high levels of endogenous dopamine do not show retinal vascular pathology.
    Front Neurosci Volume: 17 Page(s): 1125784
    01/01/2023 Authors: Allen RS; Khayat CT; Feola AJ; Win AS; Grubman AR; Chesler KC; He L; Dixon JA; Kern TS; Iuvone PM
  • ON than OFF pathway disruption leads to greater deficits in visual function and retinal dopamine signaling.
    Exp Eye Res Volume: 220 Page(s): 109091
    07/01/2022 Authors: Aung MH; Hogan K; Mazade RE; Park HN; Sidhu CS; Iuvone PM; Pardue MT
  • A NOVEL TROPOMYOSIN-RELATED KINASE-B (TRKB) RECEPTOR AGONIST PREVENTS VISION LOSS AFTER BLAST OVERPRESSURE INJURY
    Volume: 39 Page(s): A87 - A87
    06/01/2022 Authors: Modgil S; Walker LC; McDonald EF; Iuvone MP
  • Selectively disrupting connexin-36 in rod photoreceptor cells alters light adaptation in photopic ERG amplitude
    Volume: 63
    06/01/2022 Authors: Dixon JA; Modgil S; Zhang S; Ribelayga C; Iuvone PM
  • 2-Fluoro-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)nicotinamide (HIFN) protects against vision loss from closed-globe ocular trauma by activating tropomyosin-related kinase B (TrkB)
    Volume: 63
    06/01/2022 Authors: Modgil S; Walker CL; McDonald FE; Iuvone PM
  • The Circadian Clock in the Retinal Pigment Epithelium Controls the Diurnal Rhythm of Phagocytic Activity.
    Int J Mol Sci Volume: 23
    05/10/2022 Authors: DeVera C; Dixon J; Chrenek MA; Baba K; Le YZ; Iuvone PM; Tosini G
  • Melanopsin modulates refractive development and myopia.
    Exp Eye Res Volume: 214 Page(s): 108866
    01/01/2022 Authors: Chakraborty R; Landis EG; Mazade R; Yang V; Strickland R; Hattar S; Stone RA; Iuvone PM; Pardue MT
  • A Tropomycin-Related Kinase B Receptor Activator for the Management of Ocular Blast-Induced Vision Loss.
    J Neurotrauma Volume: 38 Page(s): 2896 - 2906
    10/15/2021 Authors: Dhakal S; He L; Lyuboslavsky P; Sidhu C; Chrenek MA; Sellers JT; Boatright JH; Geisert EE; Setterholm NA; McDonald FE
  • Photoreceptor Degeneration in Homozygous Male Per2luc Mice During Aging.
    J Biol Rhythms Volume: 36 Page(s): 137 - 145
    04/01/2021 Authors: Goyal V; DeVera C; Baba K; Sellers J; Chrenek MA; Iuvone PM; Tosini G
  • Ambient Light Regulates Retinal Dopamine Signaling and Myopia Susceptibility.
    Invest Ophthalmol Vis Sci Volume: 62 Page(s): 28
    01/04/2021 Authors: Landis EG; Park HN; Chrenek M; He L; Sidhu C; Chakraborty R; Strickland R; Iuvone PM; Pardue MT
  • Visual conditions affecting eye growth alter diurnal levels of vitreous DOPAC.
    Exp Eye Res Volume: 200 Page(s): 108226
    11/01/2020 Authors: Nickla DL; Sarfare S; McGeehan B; Wei W; Elin-Calcador J; He L; Dhakal S; Dixon J; Maguire MG; Stone RA
  • Resource: A multi-species multi-timepoint transcriptome database and webpage for the pineal gland and retina.
    J Pineal Res Volume: 69 Page(s): e12673
    10/01/2020 Authors: Chang E; Fu C; Coon SL; Alon S; Bozinoski M; Breymaier M; Bustos DM; Clokie SJ; Gothilf Y; Esnault C
  • Novel Detection and Restorative Levodopa Treatment for Preclinical Diabetic Retinopathy.
    Diabetes Volume: 69 Page(s): 1518 - 1527
    07/01/2020 Authors: Motz CT; Chesler KC; Allen RS; Bales KL; Mees LM; Feola AJ; Maa AY; Olson DE; Thule PM; Iuvone PM
  • Effects of Cone Connexin-36 Disruption on Light Adaptation and Circadian Regulation of the Photopic ERG.
    Invest Ophthalmol Vis Sci Volume: 61 Page(s): 24
    06/03/2020 Authors: Zhang S; Lyuboslavsky P; Dixon JA; Chrenek MA; Sellers JT; Hamm JM; Ribelayga CP; Zhang Z; Le YZ; Iuvone PM
  • Daily L-DOPA treatment in diabetic rats restores retinal dopamine and protects from retinopathy
    Volume: 61
    06/01/2020 Authors: Chesler K; Motz C; Vo H; Douglass A; Allen RS; Iuvone PM; Pardue M
  • Clock and circadian rhythm-related genes, visual input and ametropias in chick
    Volume: 61
    06/01/2020 Authors: Stone RA; Wei W; Sarfare S; McGeehan B; Engelhart KC; Khurana TS; Maguire M; Iuvone PM; Nickla DL
  • Visual defects in mice lacking circadian rhythm function in cone photoreceptors
    Volume: 61
    06/01/2020 Authors: Jess HAMM; Lyuboslavski PL; Zhang S; Chrenek MA; Iuvone PM
  • Dopamine metabolite levels in the vitreous of diabetic and non-diabetic humans.
    Exp Eye Res Volume: 195 Page(s): 108040
    06/01/2020 Authors: Hendrick A; Smith J; Stelton C; Barb S; Yan J; Cribbs B; Jain N; Yeh S; Hubbard GB; He L
  • Dopamine 2 Receptor Signaling Controls the Daily Burst in Phagocytic Activity in the Mouse Retinal Pigment Epithelium.
    Invest Ophthalmol Vis Sci Volume: 61 Page(s): 10
    05/11/2020 Authors: Goyal V; DeVera C; Laurent V; Sellers J; Chrenek MA; Hicks D; Baba K; Iuvone PM; Tosini G
  • Visual Image Quality Impacts Circadian Rhythm-Related Gene Expression in Retina and in Choroid: A Potential Mechanism for Ametropias.
    Invest Ophthalmol Vis Sci Volume: 61 Page(s): 13
    05/11/2020 Authors: Stone RA; Wei W; Sarfare S; McGeehan B; Engelhart KC; Khurana TS; Maguire MG; Iuvone PM; Nickla DL
  • Increased endogenous dopamine prevents myopia in mice.
    Exp Eye Res Volume: 193 Page(s): 107956
    04/01/2020 Authors: Landis EG; Chrenek MA; Chakraborty R; Strickland R; Bergen M; Yang V; Iuvone PM; Pardue MT
  • Roles of Cone Photoreceptor Connexin-36 in Light Adaptation and Circadian Regulation of the Photopic ERG
    Volume: 60
    07/01/2019 Authors: Zhang S; Lyubslavsky P; Dixon JA; Chrenek MA; Sellers J; Ribelayga C; Zhang Z; Xia X; Iuvone PM
  • Removal of Dopamine 2 Receptor abolishes the daily rhythm of phagocytosis in the mouse RPE.
    Volume: 60
    07/01/2019 Authors: Goyal V; De Vera C; Laurent V; Baba K; Sellers J; Chrenek MA; Hicks D; Iuvone PM; Tosini G
  • Light exposure history alters dopamine activity in the retina
    Volume: 60
    07/01/2019 Authors: Landis E; Park HN; Chrenek MA; He L; Sidhu C; Strickland R; Iuvone PM; Pardue MT
  • Short-term levodopa treatments ameliorate early stage electroretinogram (ERG) delays in diabetic patients
    Volume: 60
    07/01/2019 Authors: Motz C; Chesler K; Allen RS; Mees L; Olson D; Maa AY; Coulter M; Thule PM; Iuvone PM; Hendrick A
  • Clinically relevant timing of L-DOPA treatment in diabetic rats slows the progression of retinopathy
    Volume: 60
    07/01/2019 Authors: Chesler K; Motz C; Allen RS; Iuvone PM; Pardue MT
  • Removal of the circadian clock gene Bmal1 in the RPE abolishes the daily peak of photoreceptor outer segment disc phagocytosis
    Volume: 60
    07/01/2019 Authors: De Vera C; Dixon JA; Chrenek MA; Baba K; Iuvone PM; Tosini G
  • Clocks in the choroid: Localization of PER3 in chicks and humans
    Volume: 60
    07/01/2019 Authors: Schroedl F; Kaser-Eichberger A; Platzl C; Trost A; Runge C; Bruckner D; Bogner B; Heindl LM; Reitsamer H; Stone RA
  • Dopamine: Mechanistic Conundrums in Eye Growth Control
    Volume: 60
    07/01/2019 Authors: Sarfare S; Stone RA; Iuvone PM; Maguire MG; McGeehan B; Wei W; Elin-Calcador J; He L; Dhakal S; Dixon JA
  • An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye.
    Nat Cell Biol Volume: 21 Page(s): 420 - 429
    04/01/2019 Authors: Nguyen M-TT; Vemaraju S; Nayak G; Odaka Y; Buhr ED; Alonzo N; Tran U; Batie M; Upton BA; Darvas M
  • Lack of cone mediated retinal function increases susceptibility to form-deprivation myopia in mice.
    Exp Eye Res Volume: 180 Page(s): 226 - 230
    03/01/2019 Authors: Chakraborty R; Yang V; Park HN; Landis EG; Dhakal S; Motz CT; Bergen MA; Iuvone PM; Pardue MT
  • Altered ocular parameters from circadian clock gene disruptions.
    PLoS One Volume: 14 Page(s): e0217111
    01/01/2019 Authors: Stone RA; McGlinn AM; Chakraborty R; Lee DC; Yang V; Elmasri A; Landis E; Shaffer J; Iuvone PM; Zheng X
  • Removal of clock gene Bmal1 from the retina affects retinal development and accelerates cone photoreceptor degeneration during aging.
    Proc Natl Acad Sci U S A Volume: 115 Page(s): 13099 - 13104
    12/18/2018 Authors: Baba K; Piano I; Lyuboslavsky P; Chrenek MA; Sellers JT; Zhang S; Gargini C; He L; Tosini G; Iuvone PM
  • Dopaminergic amacrine cell number, plexus density, and dopamine content in the mouse retina: Strain differences and effects of Bax gene disruption.
    Exp Eye Res Volume: 177 Page(s): 208 - 212
    12/01/2018 Authors: Sankaran M; Keeley PW; He L; Iuvone PM; Reese BE
  • Rhythmic Regulation of Photoreceptor and RPE Genes Important for Vision and Genetically Associated With Severe Retinal Diseases.
    Invest Ophthalmol Vis Sci Volume: 59 Page(s): 3789 - 3799
    08/01/2018 Authors: Vancura P; Csicsely E; Leiser A; Iuvone PM; Spessert R
  • Diurnal Cycling of Clock and Melanopsin Genes in Chick Choroid
    Volume: 59
    07/01/2018 Authors: Stone RA; Wei W; Sarfare S; Pan W; Engelhart KC; Khurana TS; Maguire MG; Iuvone PM; Nickla DL
  • Circadian and dopamine modulation of sensitivity to light-induced retinal degeneration (LIRD) in mice
    Volume: 59
    07/01/2018 Authors: Lyuboslavsky P; Sellers JT; Tosini G; Iuvone PM
  • Daily low dose L-DOPA treatment delays the onset of retinal function deficits and improves retinal vascular function in STZ-induced diabetic rats
    Volume: 59
    07/01/2018 Authors: Chesler KC; Motz C; Allen RS; Iuvone PM; Pardue MT
  • Consequences of circadian clock disruption in the retina
    Volume: 59
    07/01/2018 Authors: Zhang S; Lyuboslavsky P; Chrenek MA; Piano I; Baba K; Tosini G; Iuvone PM
  • Removal of the clock gene Bmal1 from 661W cells affects cell viability and response to oxidative stress
    Volume: 59
    07/01/2018 Authors: Baba K; Suen T-C; Sanchez-Bretano A; DeBruyne J; Iuvone PM; Tosini G
  • Retina, Dopamine, and Circadian Rhythms
    Volume: 59
    07/01/2018 Authors: Iuvone PM
  • Lens defocus alters dopamine synthesis under different ambient lighting conditions
    Volume: 59
    07/01/2018 Authors: Landis E; Park HL; He L; Sidhu C; Chrenek MA; Strickland R; Iuvone PM; Pardue MT
  • -Synuclein stimulation of monoamine oxidase-B and legumain protease mediates the pathology of Parkinson's disease.
    EMBO J Volume: 37
    06/15/2018 Authors: Kang SS; Ahn EH; Zhang Z; Liu X; Manfredsson FP; Sandoval IM; Dhakal S; Iuvone PM; Cao X; Ye K
  • Circadian rhythms, refractive development, and myopia.
    Ophthalmic Physiol Opt Volume: 38 Page(s): 217 - 245
    05/01/2018 Authors: Chakraborty R; Ostrin LA; Nickla DL; Iuvone PM; Pardue MT; Stone RA
  • The Retinal Circadian Clock and Photoreceptor Viability.
    Adv Exp Med Biol Volume: 1074 Page(s): 345 - 350
    01/01/2018 Authors: Baba K; Ribelayga CP; Michael Iuvone P; Tosini G
  • Daily visual stimulation in the critical period enhances multiple aspects of vision through BDNF-mediated pathways in the mouse retina.
    PLoS One Volume: 13 Page(s): e0192435
    01/01/2018 Authors: Mui AM; Yang V; Aung MH; Fu J; Adekunle AN; Prall BC; Sidhu CS; Park HN; Boatright JH; Iuvone PM
  • Dopamine Deficiency Mediates Early Rod-Driven Inner Retinal Dysfunction in Diabetic Mice.
    Invest Ophthalmol Vis Sci Volume: 59 Page(s): 572 - 581
    01/01/2018 Authors: Kim MK; Aung MH; Mees L; Olson DE; Pozdeyev N; Iuvone PM; Thule PM; Pardue MT
  • Transcriptional Changes in the Mouse Retina after Ocular Blast Injury: A Role for the Immune System.
    J Neurotrauma Volume: 35 Page(s): 118 - 129
    01/01/2018 Authors: Struebing FL; King R; Li Y; Chrenek MA; Lyuboslavsky PN; Sidhu CS; Iuvone PM; Geisert EE
  • Prorenin receptor (PRR)-mediated NADPH oxidase (Nox) signaling regulates VEGF synthesis under hyperglycemic condition in ARPE-19 cells.
    J Recept Signal Transduct Res Volume: 37 Page(s): 560 - 568
    12/01/2017 Authors: Haque R; Iuvone PM; He L; Hur EH; Chung Choi KS; Park D; Farrell AN; Ngo A; Gokhale S; Aseem M
  • Dopamine signaling and myopia development: What are the key challenges.
    Prog Retin Eye Res Volume: 61 Page(s): 60 - 71
    11/01/2017 Authors: Zhou X; Pardue MT; Iuvone PM; Qu J
  • Asparagine endopeptidase cleaves -synuclein and mediates pathologic activities in Parkinson's disease.
    Nat Struct Mol Biol Volume: 24 Page(s): 632 - 642
    08/01/2017 Authors: Zhang Z; Kang SS; Liu X; Ahn EH; Zhang Z; He L; Iuvone PM; Duong DM; Seyfried NT; Benskey MJ
  • Dopamine is an Opsin 5-dependent modulator of vascular development in the eye
    Volume: 58
    06/01/2017 Authors: Lang RA; Van Gelder RN; Iuvone PM; Vemaraju S; Buhr E; Rao S; Minh-Thanh N
  • Altered dopamine release in VMAT2 mutant mice has little effect on refractive development
    Volume: 58
    06/01/2017 Authors: Landis E; Yang V; He L; Lohr K; Iuvone PM; Pardue MT
  • Effects of blue-tinted lens defocus on myopia susceptibility in mice.
    Volume: 58
    06/01/2017 Authors: Strickland RG; Landis E; Chakraborty R; Yang V; Iuvone PM; Pardue MT
  • -Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation.
    Proc Natl Acad Sci U S A Volume: 114 Page(s): 1183 - 1188
    01/31/2017 Authors: Kang SS; Zhang Z; Liu X; Manfredsson FP; He L; Iuvone PM; Cao X; Sun YE; Jin L; Ye K
  • Gnaz couples the circadian and dopaminergic system to G protein-mediated signaling in mouse photoreceptors.
    PLoS One Volume: 12 Page(s): e0187411
    01/01/2017 Authors: Vancura P; Abdelhadi S; Csicsely E; Baba K; Tosini G; Iuvone PM; Spessert R
  • The MicroRNA-21 signaling pathway is involved in prorenin receptor (PRR) -induced VEGF expression in ARPE-19 cells under a hyperglycemic condition.
    Mol Vis Volume: 23 Page(s): 251 - 262
    01/01/2017 Authors: Haque R; Iuvone PM; He L; Choi KSC; Ngo A; Gokhale S; Aseem M; Park D
  • Development of Experimental Myopia in Chicks in a Natural Environment.
    Invest Ophthalmol Vis Sci Volume: 57 Page(s): 4779 - 4789
    09/01/2016 Authors: Stone RA; Cohen Y; McGlinn AM; Davison S; Casavant S; Shaffer J; Khurana TS; Pardue MT; Iuvone PM
  • Ascorbic acid, and not L-DOPA, protects against form-deprivation myopia in retinal degeneration mouse models.
    Volume: 57
    09/01/2016 Authors: Landis E; Park H; Chakraborty R; Sidhu C; Iuvone PM; Pardue MT
  • Regulating arachidonic acid metabolites ameliorates neurovascular defects and subsequent visual deficits in STZ rats
    Volume: 57
    09/01/2016 Authors: Hanif A; Aung M; Prunty M; Park H; Iuvone PM; Pardue MT
  • Retinal defects in mice after lvermectin treatment
    Volume: 57
    09/01/2016 Authors: Chrenek MA; Sellers JT; Masters B; Struebing FL; King R; Cunha PP; Taylor D; Boatright JH; Nickerson JM; Iuvone PM
  • Activation of the immune system following blast injury to the eye
    Volume: 57
    09/01/2016 Authors: Li Y; King R; Struebing FL; Iuvone PM; Geisert EE
  • Cocaine- and amphetamine-regulated transcript (CART) regulates retinal dopamine and modulates visual function in mice
    Volume: 57
    09/01/2016 Authors: Lyuboslaysky P; Sidhu C; Sellers JT; He L; Iuvone PM
  • Altered Refractive Development in Mice With Reduced Levels of Retinal Dopamine.
    Invest Ophthalmol Vis Sci Volume: 57 Page(s): 4412 - 4419
    08/01/2016 Authors: Bergen MA; Park HN; Chakraborty R; Landis EG; Sidhu C; He L; Iuvone PM; Pardue MT
  • Is Retinal Dopamine Involved in the Loss of Visual Function in Retinopathy of Prematurity?
    Invest Ophthalmol Vis Sci Volume: 57 Page(s): 3380
    06/01/2016 Authors: Iuvone PM
  • IRBP deficiency permits precocious ocular development and myopia.
    Mol Vis Volume: 22 Page(s): 1291 - 1308
    01/01/2016 Authors: Markand S; Baskin NL; Chakraborty R; Landis E; Wetzstein SA; Donaldson KJ; Priyadarshani P; Alderson SE; Sidhu CS; Boatright JH
  • Circadian and Dopaminergic Regulation of Fatty Acid Oxidation Pathway Genes in Retina and Photoreceptor Cells.
    PLoS One Volume: 11 Page(s): e0164665
    01/01/2016 Authors: Vancura P; Wolloscheck T; Baba K; Tosini G; Iuvone PM; Spessert R
  • Neonatal aphakia is associated with altered levels of dopamine metabolites in the non-human primate retina.
    Exp Eye Res Volume: 140 Page(s): 187 - 189
    11/01/2015 Authors: Iuvone PM; Haque R; Fernandes A; Lambert SR
  • Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor.
    Hum Mol Genet Volume: 24 Page(s): 5512 - 5523
    10/01/2015 Authors: Gokhale A; Vrailas-Mortimer A; Larimore J; Comstra HS; Zlatic SA; Werner E; Manvich DF; Iuvone PM; Weinshenker D; Faundez V
  • Pgc-1 and Nr4a1 Are Target Genes of Circadian Melatonin and Dopamine Release in Murine Retina.
    Invest Ophthalmol Vis Sci Volume: 56 Page(s): 6084 - 6094
    09/01/2015 Authors: Kunst S; Wolloscheck T; Kelleher DK; Wolfrum U; Sargsyan SA; Iuvone PM; Baba K; Tosini G; Spessert R
  • ON pathway mutations increase susceptibility to form-deprivation myopia.
    Exp Eye Res Volume: 137 Page(s): 79 - 83
    08/01/2015 Authors: Chakraborty R; Park HN; Hanif AM; Sidhu CS; Iuvone PM; Pardue MT
  • Gram-scale, chemoselective synthesis of N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-oxopiperidine-3-carboxamide (HIOC).
    Tetrahedron Lett Volume: 56 Page(s): 3413 - 3415
    06/03/2015 Authors: Setterholm NA; McDonald FE; Boatright JH; Iuvone PM
  • Traumatic Blast-Induced Closed Globe Injury Reduces Visual Function and Retinal Ganglion Cells of Thy1-CFP mice: Mitigation by a Small Molecule TrkB Activator
    Volume: 56
    06/01/2015 Authors: Sidhu C; Lyuboslavsky P; Chrenek MA; Struebing FL; Sellers JT; Setterholm NA; McDonald FE; Boatright JH; Geisert EE; Iuvone PM
  • Melanopsin knock-out mice have abnormal refractive development and increased susceptibility to form-deprivation myopia
    Volume: 56
    06/01/2015 Authors: Chakraborty R; Lee DC; Landis EG; Bergen MA; Park HN; Sidhu C; Hattar S; Iuvone PM; Stone RA; Pardue MT
  • Eye Elongation and Retinal Degeneration in the IRBP Knockout Mouse
    Volume: 56
    06/01/2015 Authors: Williams N; Getz S; Sidhu C; Boatright JH; Pardue MT; Iuvone PM; Nickerson JM
  • Daily oscillation of EGR-1 expression in wild type and dopamine D4 receptor-knock-out mice
    Volume: 56
    06/01/2015 Authors: Lyuboslavsky P; Sargsyan SA; Iuvone PM
  • Examination of the mechanism of retinal protection by DMSO in murine light damage
    Volume: 56
    06/01/2015 Authors: Chrenek MA; Sellers JT; Foster SL; Iuvone PM; Boatright JH
  • Scotopic and Photopic Lighting Prevents Lens-induced Myopia in Mice
    Volume: 56
    06/01/2015 Authors: Landis E; Park HN; Prunty M; Sidhu C; Iuvone PM; Pardue MT
  • Striatal dopamine receptor plasticity in neurotensin deficient mice.
    Behav Brain Res Volume: 280 Page(s): 160 - 171
    03/01/2015 Authors: Chastain LG; Qu H; Bourke CH; Iuvone PM; Dobner PR; Nemeroff CB; Kinkead B
  • MicroRNA-152 represses VEGF and TGF1 expressions through post-transcriptional inhibition of (Pro)renin receptor in human retinal endothelial cells.
    Mol Vis Volume: 21 Page(s): 224 - 235
    01/01/2015 Authors: Haque R; Hur EH; Farrell AN; Iuvone PM; Howell JC
  • Involvement of GABA transporters in atropine-treated myopic retina as revealed by iTRAQ quantitative proteomics.
    J Proteome Res Volume: 13 Page(s): 4647 - 4658
    11/07/2014 Authors: Barathi VA; Chaurasia SS; Poidinger M; Koh SK; Tian D; Ho C; Iuvone PM; Beuerman RW; Zhou L
  • Visually-driven ocular growth in mice requires functional rod photoreceptors.
    Invest Ophthalmol Vis Sci Volume: 55 Page(s): 6272 - 6279
    09/02/2014 Authors: Park HN; Jabbar SB; Tan CC; Sidhu CS; Abey J; Aseem F; Schmid G; Iuvone PM; Pardue MT
  • Influence of ON and OFF Pathways on Visual Function Development
    Volume: 55
    04/01/2014 Authors: Aung MH; Park H; Sidhu CS; Iuvone PM; Pardue MT
  • Aerobic Exercise Sustains Retinal Function and Retinal Dopamine Metabolism in Diabetic Rats
    Volume: 55
    04/01/2014 Authors: Prall BC; Aung MH; Gogniat M; Allen RS; Sidhu CS; Boatright JH; Iuvone PM; Pardue MT
  • Cocaine- and amphetamine-regulated transcript (CART): a novel retinal neuropeptide
    Volume: 55
    04/01/2014 Authors: Sargsyan SA; Iuvone PM
  • Tauroursodeoxycholic acid (TUDCA) protects against human sub-retinal fluid toxicity in photoreceptor-enriched chick cell cultures
    Volume: 55
    04/01/2014 Authors: Cunha P; Aseem F; Daruich A; Johnson W; Girardot P; Chrenek MA; Iuvone PM; Behar-Cohen FF; Boatright JH
  • Novel method for quantifying loss of retinal ganglion cells in mice
    Volume: 55
    04/01/2014 Authors: Chrenek MA; Sellers J; Foster SL; Iuvone PM; Boatright JH
  • IRBP, Dopamine, and the Development of Early Myopia
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 55
    04/01/2014 Authors: Williams N; Getz S; Aseem F; Sidhu CS; Boatright JH; Iuvone PM; Nickerson JM
  • Outdoor Exposure Does Not Inhibit Experimental Myopia
    Volume: 55
    04/01/2014 Authors: Stone RA; Cohen Y; McGlinn AM; Davison S; Casavant S; Huang J; Khurana TS; Pardue MT; Iuvone PM
  • Circadian organization of the mammalian retina: from gene regulation to physiology and diseases.
    Prog Retin Eye Res Volume: 39 Page(s): 58 - 76
    03/01/2014 Authors: McMahon DG; Iuvone PM; Tosini G
  • Dopamine deficiency contributes to early visual dysfunction in a rodent model of type 1 diabetes.
    J Neurosci Volume: 34 Page(s): 726 - 736
    01/15/2014 Authors: Aung MH; Park HN; Han MK; Obertone TS; Abey J; Aseem F; Thule PM; Iuvone PM; Pardue MT
  • Comparison of refractive development and retinal dopamine in OFF pathway mutant and C57BL/6J wild-type mice.
    Mol Vis Volume: 20 Page(s): 1318 - 1327
    01/01/2014 Authors: Chakraborty R; Park HN; Aung MH; Tan CC; Sidhu CS; Iuvone PM; Pardue MT
  • N-acetylserotonin: circadian activation of the BDNF receptor and neuroprotection in the retina and brain.
    Adv Exp Med Biol Volume: 801 Page(s): 765 - 771
    01/01/2014 Authors: Iuvone PM; Boatright JH; Tosini G; Ye K
  • pY RNA1-s2: a highly retina-enriched small RNA that selectively binds to Matrin 3 (Matr3).
    PLoS One Volume: 9 Page(s): e88217
    01/01/2014 Authors: Yamazaki F; Kim HH; Lau P; Hwang CK; Iuvone PM; Klein D; Clokie SJH
  • The rat with oxygen-induced retinopathy is myopic with low retinal dopamine.
    Invest Ophthalmol Vis Sci Volume: 54 Page(s): 8275 - 8284
    12/19/2013 Authors: Zhang N; Favazza TL; Baglieri AM; Benador IY; Noonan ER; Fulton AB; Hansen RM; Iuvone PM; Akula JD
  • Circadian rhythm of contrast sensitivity is regulated by a dopamine-neuronal PAS-domain protein 2-adenylyl cyclase 1 signaling pathway in retinal ganglion cells.
    J Neurosci Volume: 33 Page(s): 14989 - 14997
    09/18/2013 Authors: Hwang CK; Chaurasia SS; Jackson CR; Chan GC-K; Storm DR; Iuvone PM
  • Investigating mechanisms of myopia in mice.
    Exp Eye Res Volume: 114 Page(s): 96 - 105
    09/01/2013 Authors: Pardue MT; Stone RA; Iuvone PM
  • Pharmacology of myopia and potential role for intrinsic retinal circadian rhythms.
    Exp Eye Res Volume: 114 Page(s): 35 - 47
    09/01/2013 Authors: Stone RA; Pardue MT; Iuvone PM; Khurana TS
  • Role of Dopamine Deficiency in Visual Dysfunction in Early-stage Diabetic Retinopathy
    Volume: 54
    06/01/2013 Authors: Aung M; Han M; Park HN; Abey J; Thule P; Iuvone P; Pardue M
  • On-Off Direction-Selective Retinal Ganglion Cells Co-Express CART and NPAS2, a Circadian Clock Protein
    Volume: 54
    06/01/2013 Authors: Sargsyan SA; Hwang C; Iuvone P
  • Retinal CLOCK and NPAS2: Differential Expression, Circadian Gene Regulation, and Roles in Visual Function
    Volume: 54
    06/01/2013 Authors: Hwang C; Iuvone P
  • Role of Prorenin Receptor (PRR) and NADPH Oxidase (NOX) in the Regulation of VEGF in ARPE-19 Cells under Hyperglycemic Conditions
    Volume: 54
    06/01/2013 Authors: Haque R; Iuvone P; Choi K; Park D; Farrell A; Hur E
  • Refractive Development and Form-Deprivation in Dopamine D4 Receptor Knock-Out Mice
    Volume: 54
    06/01/2013 Authors: Park HN; Tan C; Light J; Aseem F; Iuvone P; Pardue M
  • Circadian regulation of vision: control of contrast sensitivity by a dopamine -> NPAS2 -> cyclic AMP signaling pathway
    Volume: 125 Page(s): 220 - 220
    05/01/2013 Authors: Iuvone PM; Hwang CK; Chaurasia SS; Jackson CR
  • Technical brief: a comparison of two methods of euthanasia on retinal dopamine levels.
    Mol Vis Volume: 19 Page(s): 1122 - 1124
    01/01/2013 Authors: Hwang CK; Iuvone PM
  • Retinal degeneration increases susceptibility to myopia in mice.
    Mol Vis Volume: 19 Page(s): 2068 - 2079
    01/01/2013 Authors: Park H; Tan CC; Faulkner A; Jabbar SB; Schmid G; Abey J; Iuvone PM; Pardue MT
  • Global microRNA expression profiling: curcumin (diferuloylmethane) alters oxidative stress-responsive microRNAs in human ARPE-19 cells.
    Mol Vis Volume: 19 Page(s): 544 - 560
    01/01/2013 Authors: Howell JC; Chun E; Farrell AN; Hur EY; Caroti CM; Iuvone PM; Haque R
  • Is the melatonin receptor type 1 involved in the pathogenesis of glaucoma?
    J Glaucoma Volume: 22 Suppl 5 Page(s): S49 - S50
    01/01/2013 Authors: Tosini G; Iuvone M; Boatright JH
  • N-acetylserotonin: neuroprotection, neurogenesis, and the sleepy brain.
    Neuroscientist Volume: 18 Page(s): 645 - 653
    12/01/2012 Authors: Tosini G; Ye K; Iuvone PM
  • Melatonin: an underappreciated player in retinal physiology and pathophysiology.
    Exp Eye Res Volume: 103 Page(s): 82 - 89
    10/01/2012 Authors: Tosini G; Baba K; Hwang CK; Iuvone PM
  • NeuroD1 is required for survival of photoreceptors but not pinealocytes: results from targeted gene deletion studies.
    J Neurochem Volume: 123 Page(s): 44 - 59
    10/01/2012 Authors: Ochocinska MJ; Muoz EM; Veleri S; Weller JL; Coon SL; Pozdeyev N; Iuvone PM; Goebbels S; Furukawa T; Klein DC
  • Retinal dopamine mediates multiple dimensions of light-adapted vision.
    J Neurosci Volume: 32 Page(s): 9359 - 9368
    07/04/2012 Authors: Jackson CR; Ruan G-X; Aseem F; Abey J; Gamble K; Stanwood G; Palmiter RD; Iuvone PM; McMahon DG
  • N-acetyl serotonin derivatives as potent neuroprotectants for retinas.
    Proc Natl Acad Sci U S A Volume: 109 Page(s): 3540 - 3545
    02/28/2012 Authors: Shen J; Ghai K; Sompol P; Liu X; Cao X; Iuvone PM; Ye K
  • GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness.
    Am J Hum Genet Volume: 90 Page(s): 331 - 339
    02/10/2012 Authors: Peachey NS; Ray TA; Florijn R; Rowe LB; Sjoerdsma T; Contreras-Alcantara S; Baba K; Tosini G; Pozdeyev N; Iuvone PM
  • Chronic inhibition of dopamine -hydroxylase facilitates behavioral responses to cocaine in mice.
    PLoS One Volume: 7 Page(s): e50583
    01/01/2012 Authors: Gaval-Cruz M; Liles LC; Iuvone PM; Weinshenker D
  • Extracellular low pH affects circadian rhythm expression in human primary fibroblasts.
    Biochem Biophys Res Commun Volume: 416 Page(s): 337 - 342
    12/16/2011 Authors: Lee SK; Achieng E; Maddox C; Chen SC; Iuvone PM; Fukuhara C
  • Melatonin synthesis in retina: cAMP-dependent transcriptional regulation of chicken arylalkylamine N-acetyltransferase by a CRE-like sequence and a TTATT repeat motif in the proximal promoter.
    J Neurochem Volume: 119 Page(s): 6 - 17
    10/01/2011 Authors: Haque R; Chong NW; Ali F; Chaurasia SS; Sengupta T; Chun E; Howell JC; Klein DC; Iuvone PM
  • DOPAMINE D4 RECEPTORS, RETINAL FUNCTION, AND SYNCHRONIZATION OF CIRCADIAN RHYTHMS IN THE MOUSE RETINA
    Volume: 118 Page(s): 36 - 36
    08/01/2011 Authors: Iuvone PM; Jackson CR; Chaurasia SS; Aseem F; Abey J; Hwang C; Pozdeyev N; Ziesel A; Wong P; Boatright JH
  • Image defocus and altered retinal gene expression in chick: clues to the pathogenesis of ametropia.
    Invest Ophthalmol Vis Sci Volume: 52 Page(s): 5765 - 5777
    07/29/2011 Authors: Stone RA; McGlinn AM; Baldwin DA; Tobias JW; Iuvone PM; Khurana TS
  • Dopamine D receptor activation controls circadian timing of the adenylyl cyclase 1/cyclic AMP signaling system in mouse retina.
    Eur J Neurosci Volume: 34 Page(s): 57 - 64
    07/01/2011 Authors: Jackson CR; Chaurasia SS; Hwang CK; Iuvone PM
  • Phosphorylation of G protein-coupled receptor kinase 1 (GRK1) is regulated by light but independent of phototransduction in rod photoreceptors.
    J Biol Chem Volume: 286 Page(s): 20923 - 20929
    06/10/2011 Authors: Osawa S; Jo R; Xiong Y; Reidel B; Tserentsoodol N; Arshavsky VY; Iuvone PM; Weiss ER
  • N-acetylserotonin promotes hippocampal neuroprogenitor cell proliferation in sleep-deprived mice.
    Proc Natl Acad Sci U S A Volume: 108 Page(s): 8844 - 8849
    05/24/2011 Authors: Sompol P; Liu X; Baba K; Paul KN; Tosini G; Iuvone PM; Ye K
  • Localization of melatonin receptor 1 in mouse retina and its role in the circadian regulation of the electroretinogram and dopamine levels.
    PLoS One Volume: 6 Page(s): e24483
    01/01/2011 Authors: Sengupta A; Baba K; Mazzoni F; Pozdeyev NV; Strettoi E; Iuvone PM; Tosini G
  • Disulfiram attenuates drug-primed reinstatement of cocaine seeking via inhibition of dopamine -hydroxylase.
    Neuropsychopharmacology Volume: 35 Page(s): 2440 - 2449
    11/01/2010 Authors: Schroeder JP; Cooper DA; Schank JR; Lyle MA; Gaval-Cruz M; Ogbonmwan YE; Pozdeyev N; Freeman KG; Iuvone PM; Edwards GL
  • CLOCK and NPAS2 have overlapping roles in the circadian oscillation of arylalkylamine N-acetyltransferase mRNA in chicken cone photoreceptors.
    J Neurochem Volume: 113 Page(s): 1296 - 1306
    06/01/2010 Authors: Haque R; Ali FG; Biscoglia R; Abey J; Weller J; Klein D; Iuvone PM
  • Refraction in an Oxygen-Induced Retinopathy (OIR) Rat Model of Retinopathy of Prematurity (ROP): Is the "ROP Rat" a Good Model?
    Volume: 51
    04/01/2010 Authors: Akula JD; Moskowitz A; Pardue MT; Iuvone PM; Mocko JA; Hansen RM; Fulton AB
  • Rod Photoreceptor Contributions to Refractive Development and Form Deprivation Myopia in Mice
    Volume: 51
    04/01/2010 Authors: Jabbar SB; Faulkner AE; Schmid GF; Schaeffel F; Abey J; Iuvone PM; Pardue MT
  • NQO2: A Novel Target to Mediate Neuroprotection Against Retinal Degeneration
    Volume: 51
    04/01/2010 Authors: Hwang CK; Zhou H; Haque R; Iuvone PM
  • N-acetylserotonin activates TrkB receptor in a circadian rhythm.
    Proc Natl Acad Sci U S A Volume: 107 Page(s): 3876 - 3881
    02/23/2010 Authors: Jang S-W; Liu X; Pradoldej S; Tosini G; Chang Q; Iuvone PM; Ye K
  • CIRCADIAN CLOCKS IN RETINA OF GOLDFISH
    Page(s): 251 - 259
    01/01/2010 Authors: Iuvone PM; Velarde E; Delgado MJ; Alonso-Gomez AL; Haque R
  • Melatonin modulates visual function and cell viability in the mouse retina via the MT1 melatonin receptor.
    Proc Natl Acad Sci U S A Volume: 106 Page(s): 15043 - 15048
    09/01/2009 Authors: Baba K; Pozdeyev N; Mazzoni F; Contreras-Alcantara S; Liu C; Kasamatsu M; Martinez-Merlos T; Strettoi E; Iuvone PM; Tosini G
  • Nonmotor symptoms of Parkinson's disease revealed in an animal model with reduced monoamine storage capacity.
    J Neurosci Volume: 29 Page(s): 8103 - 8113
    06/24/2009 Authors: Taylor TN; Caudle WM; Shepherd KR; Noorian A; Jackson CR; Iuvone PM; Weinshenker D; Greene JG; Miller GW
  • Circadian clock genes of goldfish, Carassius auratus: cDNA cloning and rhythmic expression of period and cryptochrome transcripts in retina, liver, and gut.
    J Biol Rhythms Volume: 24 Page(s): 104 - 113
    04/01/2009 Authors: Velarde E; Haque R; Iuvone PM; Azpeleta C; Alonso-Gmez AL; Delgado MJ
  • Essential roles of dopamine D4 receptors and the type 1 adenylyl cyclase in photic control of cyclic AMP in photoreceptor cells.
    J Neurochem Volume: 109 Page(s): 148 - 157
    04/01/2009 Authors: Jackson CR; Chaurasia SS; Zhou H; Haque R; Storm DR; Iuvone PM
  • Light regulation of retinal dopamine that is independent of melanopsin phototransduction.
    Eur J Neurosci Volume: 29 Page(s): 761 - 767
    02/01/2009 Authors: Cameron MA; Pozdeyev N; Vugler AA; Cooper H; Iuvone PM; Lucas RJ
  • CLOCK is required for maintaining the circadian rhythms of Opsin mRNA expression in photoreceptor cells.
    J Biol Chem Volume: 283 Page(s): 31673 - 31678
    11/14/2008 Authors: Li P; Chaurasia SS; Gao Y; Carr AL; Iuvone PM; Li L
  • The circadian clock system in the mammalian retina.
    Bioessays Volume: 30 Page(s): 624 - 633
    07/01/2008 Authors: Tosini G; Pozdeyev N; Sakamoto K; Iuvone PM
  • Dopamine D4 receptors regulate intracellular calcium concentration in cultured chicken cone photoreceptor cells: relationship to dopamine receptor-mediated inhibition of cAMP formation.
    Brain Res Volume: 1207 Page(s): 111 - 119
    05/01/2008 Authors: Ivanova TN; Alonso-Gomez AL; Iuvone PM
  • Dopamine modulates diurnal and circadian rhythms of protein phosphorylation in photoreceptor cells of mouse retina.
    Eur J Neurosci Volume: 27 Page(s): 2691 - 2700
    05/01/2008 Authors: Pozdeyev N; Tosini G; Li L; Ali F; Rozov S; Lee RH; Iuvone PM
  • High susceptibility to experimental myopia in a mouse model with a retinal on pathway defect.
    Invest Ophthalmol Vis Sci Volume: 49 Page(s): 706 - 712
    02/01/2008 Authors: Pardue MT; Faulkner AE; Fernandes A; Yin H; Schaeffel F; Williams RW; Pozdeyev N; Iuvone PM
  • Specific alterations of tyrosine hydroxylase immunopositive cells in the retina of NT-4 knock out mice.
    Vision Res Volume: 47 Page(s): 1523 - 1536
    05/01/2007 Authors: Calamusa M; Pattabiraman PP; Pozdeyev N; Iuvone PM; Cellerino A; Domenici L
  • Head-mounted goggles for murine form deprivation myopia.
    J Neurosci Methods Volume: 161 Page(s): 96 - 100
    03/30/2007 Authors: Faulkner AE; Kim MK; Iuvone PM; Pardue MT
  • Temporal coupling of cyclic AMP and Ca/calmodulin-stimulated adenylyl cyclase to the circadian clock in chick retinal photoreceptor cells.
    J Neurochem Volume: 99 Page(s): 1142 - 1150
    11/01/2006 Authors: Chaurasia SS; Haque R; Pozdeyev N; Jackson CR; Iuvone PM
  • Photic regulation of arylalkylamine N-acetyltransferase binding to 14-3-3 proteins in retinal photoreceptor cells.
    J Neurosci Volume: 26 Page(s): 9153 - 9161
    09/06/2006 Authors: Pozdeyev N; Taylor C; Haque R; Chaurasia SS; Visser A; Thazyeen A; Du Y; Fu H; Weller J; Klein DC
  • Evolution of melanopsin photoreceptors: discovery and characterization of a new melanopsin in nonmammalian vertebrates.
    PLoS Biol Volume: 4 Page(s): e254
    07/01/2006 Authors: Bellingham J; Chaurasia SS; Melyan Z; Liu C; Cameron MA; Tarttelin EE; Iuvone PM; Hankins MW; Tosini G; Lucas RJ
  • Angiostatin decreases cell migration and vascular endothelium growth factor (VEGF) to pigment epithelium derived factor (PEDF) RNA ratio in vitro and in a murine ocular melanoma model.
    Mol Vis Volume: 12 Page(s): 511 - 517
    05/22/2006 Authors: Yang H; Xu Z; Iuvone PM; Grossniklaus HE
  • Circadian clockwork machinery in neural retina: evidence for the presence of functional clock components in photoreceptor-enriched chick retinal cell cultures.
    Mol Vis Volume: 12 Page(s): 215 - 223
    03/30/2006 Authors: Chaurasia SS; Pozdeyev N; Haque R; Visser A; Ivanova TN; Iuvone PM
  • Intraocular injection of kainic acid does not abolish the circadian rhythm of arylalkylamine N-acetyltransferase mRNA in rat photoreceptors.
    Mol Vis Volume: 12 Page(s): 117 - 124
    02/23/2006 Authors: Sakamoto K; Liu C; Kasamatsu M; Iuvone PM; Tosini G
  • Regulation of melatonin synthesis in avian retina by circadian clocks and light: Cellular and molecular mechanisms
    Volume: 305A Page(s): 136 - 136
    02/01/2006 Authors: Iuvone PM
  • Regulation of arylalkylamine N-acetyltransferase (AANAT) in the retina.
    Chronobiol Int Volume: 23 Page(s): 381 - 391
    01/01/2006 Authors: Tosini G; Chaurasia SS; Michael Iuvone P
  • Dopamine regulates melanopsin mRNA expression in intrinsically photosensitive retinal ganglion cells.
    Eur J Neurosci Volume: 22 Page(s): 3129 - 3136
    12/01/2005 Authors: Sakamoto K; Liu C; Kasamatsu M; Pozdeyev NV; Iuvone PM; Tosini G
  • Imaging of Ca2+ dynamics within the presynaptic terminals of salamander rod photoreceptors.
    J Neurophysiol Volume: 94 Page(s): 4544 - 4553
    12/01/2005 Authors: Steele EC; Chen X; Iuvone PM; MacLeish PR
  • UV-A light regulation of arylalkylamine N-acetyltransferase activity in the chick pineal gland: role of cAMP and proteasomal proteolysis.
    J Pineal Res Volume: 39 Page(s): 419 - 424
    11/01/2005 Authors: Rosiak J; Michael Iuvone P; Zawilska JB
  • Circadian clocks, clock networks, arylalkylamine N-acetyltransferase, and melatonin in the retina.
    Prog Retin Eye Res Volume: 24 Page(s): 433 - 456
    07/01/2005 Authors: Iuvone PM; Tosini G; Pozdeyev N; Haque R; Klein DC; Chaurasia SS
  • Neonatal aphakia retards ocular growth and alters scleral gene expression in rhesus monkeys.
    Mol Vis Volume: 11 Page(s): 36 - 49
    01/13/2005 Authors: Tarnuzzer RW; Fernandes A; Iuvone PM; Lambert SR
  • Melatonin synthesis in chicken retina: Regulation of arylalkylamine N-acetyltransferase binding to 14-3-3 proteins by light and darkness
    Volume: 46
    01/01/2005 Authors: Pozdeyev N; Chaurasia SS; Haque R; Du Y; Fu H; Iuvone PM
  • Mouse model with ON pathway defect has increased susceptibility to form deprivation myopia
    Volume: 46
    01/01/2005 Authors: Fernandez A; Yin H; Faulkner AE; Iuvone PM; Williams RW; Schaeffel F; Pardue MT
  • Gene expression associated with lens-induced myopia in Rhesus monkeys
    Volume: 46
    01/01/2005 Authors: Lambert SR; Fernandes A; Haque R; Smith EL; Iuvone PM
  • Vascular endothelial growth factor (VEGF) and pigment epithelium derived factor (PEDF) in micrometastatic ocular melanoma in a murine model
    Volume: 46
    01/01/2005 Authors: Yang H; Xu Z; Iuvone PM; Arbiser JL; Crawford SE; Stellmach VM; Grossniklaus HE
  • Molecular cloning, localization and circadian expression of chicken melanopsin (Opn4): differential regulation of expression in pineal and retinal cell types.
    J Neurochem Volume: 92 Page(s): 158 - 170
    01/01/2005 Authors: Chaurasia SS; Rollag MD; Jiang G; Hayes WP; Haque R; Natesan A; Zatz M; Tosini G; Liu C; Korf HW
  • Rhythmic melatonin synthesis and circadian clock gene expression in cultured chicken retinal cells
    Volume: 46
    01/01/2005 Authors: Iuvone PM; Chaurasia SS; Bogenpohl J; Ivanova T; Pozdeyev N; Visser A; Haque R
  • Diurnal rhythms of tryptophan hydroxylase 1 and 2 mRNA expression in the rat retina.
    Neuroreport Volume: 15 Page(s): 1497 - 1500
    06/28/2004 Authors: Liang J; Wessel JH; Iuvone PM; Tosini G; Fukuhara C
  • Differential circadian regulation of melanopsin mRNA expression in the avian retina and pineal gland
    Volume: 45 Page(s): U489 - U489
    04/01/2004 Authors: Chaurasia SS; Provencio I; Jiang G; Hayes WP; Haque R; Natesan A; Zatz M; Rollag MD; Iuvone PM
  • Retinal melatonin biosynthesis: Interactions of A/T-rich regions and CRE-like sequences contribute to cAMP-dependent regulation of the chicken AANAT promoter.
    Volume: 45 Page(s): U315 - U315
    04/01/2004 Authors: Haque R; Chong NW; Chaurasia SS; Klein DC; Iuvone PM
  • Circadian rhythms of Ca2+/calmodulin-stimulated adenylyl cyclase mRNA expression and CREB phosphorylation in chicken retina
    Volume: 45 Page(s): U488 - U488
    04/01/2004 Authors: Iuvone PM; Chaurasia SS; Ivanova TN; Wessel JH; Haque R
  • Gene expression associated with lens-induced myopia in Rhesus monkeys
    Volume: 45 Page(s): U506 - U506
    04/01/2004 Authors: Lambert SR; Fernandes A; Haque R; Smith EL; Iuvone PM
  • Effects of form deprivation on eye size and refraction in C57BL/6J mice
    Volume: 45 Page(s): U414 - U414
    04/01/2004 Authors: Fernandes A; Yin H; Byron EA; Iuvone PM; Schaffel F; Williams RW; Pardue MT
  • Gating of the cAMP signaling cascade and melatonin synthesis by the circadian clock in mammalian retina.
    J Neurosci Volume: 24 Page(s): 1803 - 1811
    02/25/2004 Authors: Fukuhara C; Liu C; Ivanova TN; Chan GC-K; Storm DR; Iuvone PM; Tosini G
  • Localization of Aa-nat mRNA in the rat retina by fluorescence in situ hybridization and laser capture microdissection.
    Cell Tissue Res Volume: 315 Page(s): 197 - 201
    02/01/2004 Authors: Liu C; Fukuhara C; Wessel JH; Iuvone PM; Tosini G
  • Spatial, temporal, and intensive determinants of dopamine release in the chick retina.
    Vis Neurosci Volume: 21 Page(s): 627 - 635
    01/01/2004 Authors: Luft WA; Iuvone PM; Stell WK
  • Circadian rhythm and photic control of cAMP level in chick retinal cell cultures: a mechanism for coupling the circadian oscillator to the melatonin-synthesizing enzyme, arylalkylamine N-acetyltransferase, in photoreceptor cells.
    Brain Res Volume: 991 Page(s): 96 - 103
    11/21/2003 Authors: Ivanova TN; Iuvone PM
  • Melatonin synthesis in retina: circadian regulation of arylalkylamine N-acetyltransferase activity in cultured photoreceptor cells of embryonic chicken retina.
    Brain Res Volume: 973 Page(s): 56 - 63
    05/23/2003 Authors: Ivanova TN; Iuvone PM
  • Expression of cMOP4, a putative clock component in retina, pineal gland and peripheral tissues
    Volume: 44 Page(s): U70 - U70
    05/01/2003 Authors: Chaurasia SS; Haque R; Chong HW; Klein DC; Iuvone PM
  • Gating of the cAMP signaling cascade by the circadian clock in mammalian retina
    Volume: 44 Page(s): U213 - U213
    05/01/2003 Authors: Tosini GG; Fukuhara C; Cuimei L; Ivanova TN; Chan GCK; Storm DR; Iuvone PM
  • Abnormal expression of calcium/calmodulin-stimulated adenylyl cyclase in photoreceptors of dopamine D4 receptor-deficient mice
    Volume: 44 Page(s): U329 - U329
    05/01/2003 Authors: Iuvone PM; Chaurasia SS; Carpenter HE; Haque R; Wessel JH
  • Circadian expression of Bmal1 in chicken retina, pineal gland, and peripheral tissues
    Volume: 44 Page(s): U70 - U70
    05/01/2003 Authors: Haque R; Chaurasia SS; Chong NW; Klein DC; Iuvone PM
  • Temporal-spatial characterization of chicken clock genes: circadian expression in retina, pineal gland, and peripheral tissues.
    J Neurochem Volume: 85 Page(s): 851 - 860
    05/01/2003 Authors: Chong NW; Chaurasia SS; Haque R; Klein DC; Iuvone PM
  • Circadian and photic regulation of cAMP: A mechanism for coupling the circadian
    Volume: 44 Page(s): U70 - U70
    05/01/2003 Authors: Ivanova TN; Iuvone PM
  • Diurnal regulation of arylalkylamine N-acetyltransferase activity in chicken retinal cells in vitro: analysis of culture conditions.
    Mol Vis Volume: 9 Page(s): 52 - 59
    03/05/2003 Authors: Haque R; Alonso-Gmez AL; Chaurasia SS; Iuvone PM
  • Dual regulation of cryptochrome 1 mRNA expression in chicken retina by light and circadian oscillators.
    Neuroreport Volume: 13 Page(s): 2247 - 2251
    12/03/2002 Authors: Haque R; Chaurasia SS; Wessel JH; Iuvone PM
  • Lack of prolactin receptor signaling in mice results in lactotroph proliferation and prolactinomas by dopamine-dependent and -independent mechanisms.
    J Clin Invest Volume: 110 Page(s): 973 - 981
    10/01/2002 Authors: Schuff KG; Hentges ST; Kelly MA; Binart N; Kelly PA; Iuvone PM; Asa SL; Low MJ
  • Circadian clock genes in chicken retina: Temporal regulation of cryptochrome 1 (cCry 1) expression
    Volume: 43 Page(s): U306 - U306
    05/01/2002 Authors: Haque R; Chaurasia SS; Iuvone PM
  • Altered levels of dopamine metabolites and vasoactive intestinal peptide (VIP) in retinas of aphakic monkey eyes
    Volume: 43 Page(s): U37 - U37
    05/01/2002 Authors: Fernandes A; Haque R; Tigges M; Iuvone PM; Lamber SR
  • Development of circadian rhythms of serotonin N-acetyltransfierase activity in photorcceptor-enriched cell culture of chick embryo retina
    Volume: 43 Page(s): U305 - U305
    05/01/2002 Authors: Ivanova TN; Iuvone PM
  • Dysfunctional light-evoked regulation of cAMP in photoreceptors and abnormal retinal adaptation in mice lacking dopamine D4 receptors.
    J Neurosci Volume: 22 Page(s): 2063 - 2073
    03/15/2002 Authors: Nir I; Harrison JM; Haque R; Low MJ; Grandy DK; Rubinstein M; Iuvone PM
  • Retinal melatonin production: role of proteasomal proteolysis in circadian and photic control of arylalkylamine N-acetyltransferase.
    Invest Ophthalmol Vis Sci Volume: 43 Page(s): 564 - 572
    02/01/2002 Authors: Iuvone PM; Brown AD; Haque R; Weller J; Zawilska JB; Chaurasia SS; Ma M; Klein DC
  • Calcium influx in depolarized photoreceptor cells: reduction by calmodulin kinase inhibitors
    JOURNAL OF NEUROCHEMISTRY Volume: 78 Page(s): 148 - 148
    09/01/2001 Authors: Iuvone PM; Ivanova TN; Alonso-Gomez AL; Uchida K
  • Novel mechanism of light-induced degradation of melatonin in the retina
    JOURNAL OF NEUROCHEMISTRY Volume: 78 Page(s): 156 - 156
    09/01/2001 Authors: Pozdeyev NV; Iuvone PM
  • Regulation of cAMP by light and dopamine receptors is dysfunctional in photoreceptors of dystrophic retinal degeneration slow(rds) mice.
    Exp Eye Res Volume: 73 Page(s): 265 - 272
    08/01/2001 Authors: Nir I; Haque R; Iuvone PM
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    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 42 Page(s): S354 - S354
    03/15/2001 Authors: Haque R; Chong NW; Klein DC; Iuvone PM
  • Activation of dopaminergic amacrine cells and release of dopamine in response to visual stimulus.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 42 Page(s): S674 - S674
    03/15/2001 Authors: Luft WA; Iuvone PM; Stell WK
  • The role of dopamine in the locomotor stimulant effects and tolerance to these effects of caffeine.
    Pharmacol Biochem Behav Volume: 69 Page(s): 59 - 70
    01/01/2001 Authors: Powell KR; Iuvone PM; Holtzman SG
  • Diurnal metabolism of dopamine in dystrophic retinas of homozygous and heterozygous retinal degeneration slow (rds) mice.
    Brain Res Volume: 884 Page(s): 13 - 22
    11/24/2000 Authors: Nir I; Haque R; Iuvone PM
  • Behavioral Evaluation of Hemiparkinsonian MPTP Monkeys following Dopamine Pharmacological Manipulation and Adrenal Co-Graft Transplantation.
    Cell Transplant Volume: 9 Page(s): 609 - 622
    09/01/2000 Authors: Howell LL; Byrd LD; Mcdonough AM; Iuvone PM; Bakay RAE
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    Brain Res Volume: 870 Page(s): 118 - 125
    07/07/2000 Authors: Nir I; Haque R; Iuvone PM
  • Regulation of tryptophan hydroxylase activity in Xenopus laevis photoreceptor cells by cyclic AMP.
    J Neurochem Volume: 74 Page(s): 1961 - 1967
    05/01/2000 Authors: Valenciano AI; Alonso-Gmez AL; Iuvone PM
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    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 41 Page(s): S112 - S112
    03/15/2000 Authors: Iuvone PM; Valenciano AI; Alonso-Gomez AI
  • Dopamine D1 receptor expression in cultured human and monkey retinal pigment epithelial cells.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 41 Page(s): S843 - S843
    03/15/2000 Authors: Haque R; Maltseva O; Ivanova T; Iuvone PM
  • Behavioral evaluation of hemiparkinsonian MPTP monkeys following dopamine pharmacological manipulation and adrenal co-graft transplantation.
    Cell Transplant Volume: 9 Page(s): 609 - 622
    01/01/2000 Authors: Howel LL; Byrd LD; McDonough AM; Iuvone PM; Bakay RA
  • Serotonin N-acetyltransferase mRNA levels in photoreceptor-enriched chicken retinal cell cultures: elevation by cyclic AMP.
    J Neurochem Volume: 73 Page(s): 1894 - 1900
    11/01/1999 Authors: Grve P; Alonso-Gmez A; Bernard M; Ma M; Haque R; Klein DC; Iuvone PM
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    Neuroreport Volume: 10 Page(s): 2131 - 2135
    07/13/1999 Authors: Valenciano AI; Alonso-Gmez AL; Iuvone PM
  • Effects of muscarinic cholinergic receptor antagonists on postnatal eye growth of rhesus monkeys.
    Optom Vis Sci Volume: 76 Page(s): 397 - 407
    06/01/1999 Authors: Tigges M; Iuvone PM; Fernandes A; Sugrue MF; Mallorga PJ; Laties AM; Stone RA
  • Dopamine mediates circadian rhythms of rod-cone dominance in the Japanese quail retina.
    J Neurosci Volume: 19 Page(s): 4132 - 4141
    05/15/1999 Authors: Manglapus MK; Iuvone PM; Underwood H; Pierce ME; Barlow RB
  • Melatonin receptor blockers and pre-treatment with dim light enhance photoreceptor survival in light damage
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 40 Page(s): S159 - S159
    03/15/1999 Authors: Bush RA; Sugawara T; Machida S; Iuvone PM; Sieving PA
  • Photoreceptor cell biology and dopamine metabolism in retinas of dopamine D4 receptor knockout mice
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 40 Page(s): S610 - S610
    03/15/1999 Authors: Nir I; Harrison JM; Rubinstein M; Low MJ; Grandy DK; Iuvone PM
  • Cyclic GMP regulates cyclic AMP formation and melatonin biosynthesis via a calcium-dependent pathway in cultured chicken photoreceptor cells
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 40 Page(s): S611 - S611
    03/15/1999 Authors: Haque R; Iuvone PM
  • Intracellular Ca2+ concentrations in cultured chicken photoreceptor cells: sustained elevation in depolarized cells and the role of dihydropyridine-sensitive Ca2+ channels.
    Mol Vis Volume: 5 Page(s): 1
    02/10/1999 Authors: Uchida K; Iuvone PM
  • Melatonin biosynthesis in chicken retina. Regulation of tryptophan hydroxylase and arylalkylamine N-acetyltransferase.
    Adv Exp Med Biol Volume: 460 Page(s): 31 - 41
    01/01/1999 Authors: Iuvone PM; Chong NW; Bernard M; Brown AD; Thomas KB; Klein DC
  • Melatonin receptor blockers enhance photoreceptor survival and function in light damaged rat retina
    Page(s): 539 - 550
    01/01/1999 Authors: Bush RA; Sugawara T; Iuvone PM; Sieving PA
  • Elevation of melatonin in chicken retina by 5-hydroxytryptophan: differential light/dark responses.
    Neuroreport Volume: 9 Page(s): 4041 - 4044
    12/21/1998 Authors: Thomas KB; Brown AD; Iuvone PM
  • The melatonin antagonist luzindole protects retinal photoreceptors from light damage in the rat.
    Invest Ophthalmol Vis Sci Volume: 39 Page(s): 2458 - 2465
    11/01/1998 Authors: Sugawara T; Sieving PA; Iuvone PM; Bush RA
  • Circadian expression of tryptophan hydroxylase mRNA in the chicken retina.
    Brain Res Mol Brain Res Volume: 61 Page(s): 243 - 250
    10/30/1998 Authors: Chong NW; Cassone VM; Bernard M; Klein DC; Iuvone PM
  • Highly sensitive and specific assay of plasma melatonin using high-performance liquid chromatography with fluorescence detection preceded by solid-phase extraction.
    J Chromatogr Sci Volume: 36 Page(s): 175 - 178
    04/01/1998 Authors: Kulczykowska E; Iuvone PM
  • Depolarization and activation of dihydropyridine-sensitive Ca2+ channels stimulate inositol phosphate accumulation in photoreceptor-enriched chick retinal cell cultures.
    J Neurochem Volume: 68 Page(s): 2300 - 2307
    06/01/1997 Authors: Gan J; Iuvone PM
  • Intracellular calcium concentrations of cultured cells: Sustained elevation in depolarized cells and effects of calmodulin kinase inhibitors.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 38 Page(s): 2862 - 2862
    03/15/1997 Authors: Uchida K; Iuvone PM
  • Cellular and molecular regulation of serotonin N-acetyltransferase activity in chicken retinal photoreceptors.
    Biol Signals Volume: 6 Page(s): 217 - 224
    01/01/1997 Authors: Iuvone PM; Bernard M; Alonso-Gomez A; Greve P; Cassone VM; Klein DC
  • The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland.
    Recent Prog Horm Res Volume: 52 Page(s): 307 - 357
    01/01/1997 Authors: Klein DC; Coon SL; Roseboom PH; Weller JL; Bernard M; Gastel JA; Zatz M; Iuvone PM; Rodriguez IR; Bgay V
  • Chicken arylalkylamine N-acetyltransferase: Cloning and circadian regulation in the pineal gland
    Page(s): 29 - 36
    01/01/1997 Authors: Bernard M; Iuvone PM; Cassone VM; Roseboom PH; Coon SL; Klein DC
  • Avian melatonin synthesis: photic and circadian regulation of serotonin N-acetyltransferase mRNA in the chicken pineal gland and retina.
    J Neurochem Volume: 68 Page(s): 213 - 224
    01/01/1997 Authors: Bernard M; Iuvone PM; Cassone VM; Roseboom PH; Coon SL; Klein DC
  • Circadian rhythms of melatonin biosynthesis in retinal photoreceptor cells - Signal transduction, interactions with dopamine, and speculations on a role in cell survival
    Page(s): 3 - 13
    01/01/1996 Authors: Iuvone PM
  • Melatonin biosynthesis in cultured chick retinal photoreceptor cells: calcium and cyclic AMP protect serotonin N-acetyltransferase from inactivation in cycloheximide-treated cells.
    J Neurochem Volume: 65 Page(s): 1054 - 1060
    09/01/1995 Authors: Alonso-Gmez AL; Iuvone PM
  • Melatonin biosynthesis in photoreceptor-enriched chick retinal cell cultures: role of cyclic AMP in the K(+)-evoked, Ca(2+)-dependent induction of serotonin N-acetyltransferase activity.
    Neurochem Int Volume: 27 Page(s): 147 - 155
    08/01/1995 Authors: Gan J; Alonso-Gmez AL; Avendano G; Johnson B; Iuvone PM
  • Stimulation of dopaminergic amacrine cells by stroboscopic illumination or fibroblast growth factor (bFGF, FGF-2) injections: possible roles in prevention of form-deprivation myopia in the chick.
    Brain Res Volume: 686 Page(s): 169 - 181
    07/24/1995 Authors: Rohrer B; Iuvone PM; Stell WK
  • 5-Methoxytryptamine inhibits cyclic AMP accumulation in cultured retinal neurons through activation of a pertussis toxin-sensitive site distinct from the 2-[125I]iodomelatonin binding site.
    J Neurochem Volume: 64 Page(s): 1892 - 1895
    04/01/1995 Authors: Iuvone PM; Gan J; Alonso-Gmez AL
  • CYCLIC EXPRESSION OF HYDROXYINDOLE-O-METHYLTRANSFERASE (HIOMT) MESSENGER-RNA IN A SUBPOPULATION OF CHICKEN PHOTORECEPTORS
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 36 Page(s): S277 - S277
    03/15/1995 Authors: WEICHMANN AF; IUVONE PM; SIMONNEAUX V; CRAFT CM
  • ROLE OF CALMODULIN IN THE REGULATION OF SEROTONIN N-ACETYLTRANSFERASE ACTIVITY IN CULTURED CHICK RETINAL PHOTORECEPTOR CELLS
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 36 Page(s): S512 - S512
    03/15/1995 Authors: ALONSOGOMEZ AL; IUVONE PM
  • STROBOSCOPIC LIGHT PREVENTS FORM-DEPRIVATION MYOPIA (FDM) IN THE CHICK BY PROMOTING DOPAMINE (DA) SYNTHESIS
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 36 Page(s): S414 - S414
    03/15/1995 Authors: ROHRER B; IUVONE PM; STELL WK
  • MELATONIN BIOSYNTHESIS IN CHICKEN PHOTORECEPTOR CELLS - DOPAMINE REGULATES THE SENSITIVITY TO INHIBITION BY ACUTE LIGHT EXPOSURE
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 36 Page(s): S512 - S512
    03/15/1995 Authors: IUVONE PM; TAYLOR MM; GOE LC
  • CHRONIC CAFFEINE INGESTION BY RATS REDUCES DOPAMINE-STIMULATED CAMP ACCUMULATION IN STRIATAL SLICES
    FASEB JOURNAL Volume: 9 Page(s): A405 - A405
    03/09/1995 Authors: IUVONE PM; FRIEL C; LONG S; JOHNSON B
  • Functional interaction of melatonin receptors and D1 dopamine receptors in cultured chick retinal neurons.
    J Neurosci Volume: 15 Page(s): 2179 - 2185
    03/01/1995 Authors: Iuvone PM; Gan J
  • Melatonin receptor-mediated inhibition of cyclic AMP accumulation in chick retinal cell cultures.
    J Neurochem Volume: 63 Page(s): 118 - 124
    07/01/1994 Authors: Iuvone PM; Gan J
  • Inhibition of endogenous dopamine release in amphibian retina by L-2-amino-4-phosphonobutyric acid (L-AP4) and trans-2-aminocyclopentane-1,3-dicarboxylate (ACPD).
    Brain Res Volume: 649 Page(s): 339 - 342
    06/27/1994 Authors: Boatright JH; Gordon JR; Iuvone PM
  • Alterations in light-evoked dopamine metabolism in dystrophic retinas of mutant rds mice.
    Brain Res Volume: 649 Page(s): 85 - 94
    06/27/1994 Authors: Nir I; Iuvone PM
  • Photomechanical movements of cultured embryonic photoreceptors: regulation by exogenous neuromodulators and by a regulable source of endogenous dopamine.
    J Neurosci Volume: 14 Page(s): 3083 - 3096
    05/01/1994 Authors: Stenkamp DL; Iuvone PM; Adler R
  • STIMULUS-TRANSCRIPTION COUPLING IN AMACRINE CELLS (ACS) - INVOLVEMENT OF PROTOONCOGENE C-FOS IN FORM-DEPRIVATION MYOPIA (FDM) IN THE CHICKEN
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 35 Page(s): 1802 - 1802
    03/15/1994 Authors: ROHRER B; IUVONE PM; STELL WK
  • STIMULATION OF INOSITOL PHOSPHATE ACCUMULATION IN RETINAL NEURONS VIA ACTIVATION OF D1-LIKE DOPAMINE-RECEPTORS
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 35 Page(s): 2154 - 2154
    03/15/1994 Authors: IUVONE PM; GAN J
  • GLUTAMATE RECEPTOR-MEDIATED REGULATION OF DOPAMINE RELEASE IN AMPHIBIAN RETINA
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 35 Page(s): 1361 - 1361
    03/15/1994 Authors: RUBIM NM; IUVONE PM
  • MELATONIN BIOSYNTHESIS IN CHICK RETINAL PHOTORECEPTOR CELLS - STIMULATION OF SEROTONIN N-ACETYLTRANFERASE ACTIVITY BY ADENOSINE RECEPTOR AGONISTS
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 35 Page(s): 1583 - 1583
    03/15/1994 Authors: GAN J; ROSENBAUM S; MOWREY JO; LEE Z; JOHNSON B; IUVONE PM
  • Regulation of endogenous dopamine release in amphibian retina by gamma-aminobutyric acid and glycine.
    Vis Neurosci Volume: 11 Page(s): 1003 - 1012
    01/01/1994 Authors: Boatright JH; Rubim NM; Iuvone PM
  • Regulation of endogenous dopamine release in amphibian retina by melatonin: the role of GABA.
    Vis Neurosci Volume: 11 Page(s): 1013 - 1018
    01/01/1994 Authors: Boatright JH; Rubim NM; Iuvone PM
  • CALCIUM INFLUX THROUGH DIHYDROPYRIDINE SENSITIVE CHANNELS STIMULATES INOSITOL PHOSPHATE ACCUMULATION IN PHOTORECEPTOR ENRICHED RETINAL CELL-CULTURES
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 34 Page(s): 1326 - 1326
    03/15/1993 Authors: GAN J; IUVONE PM
  • NMDA RECEPTORS REGULATE DOPAMINE RELEASE IN AMPHIBIAN RETINA
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 34 Page(s): 1063 - 1063
    03/15/1993 Authors: RUBIM NM; BOATRIGHT JH; GORDON JR; IUVONE PM
  • DIURNAL RHYTHM OF DOPAMINE METABOLISM IS ABSENT IN RETINAS OF MUTANT RDS MICE
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 34 Page(s): 768 - 768
    03/15/1993 Authors: NIR I; IUVONE PM
  • Melatonin synthesis and circadian tryptophan hydroxylase activity in chicken retina following destruction of serotonin immunoreactive amacrine and bipolar cells by kainic acid.
    Brain Res Volume: 601 Page(s): 303 - 307
    01/22/1993 Authors: Thomas KB; Tigges M; Iuvone PM
  • Regulation of melatonin and dopamine biosynthesis in chick retina: the role of GABA.
    Vis Neurosci Volume: 10 Page(s): 621 - 629
    01/01/1993 Authors: Kazula A; Nowak JZ; Iuvone PM
  • 2-AMINO-4-PHOSPHONOBUTYRIC ACID (AP-4) BLOCKS LIGHT-EVOKED DOPAMINE RELEASE IN FROG RETINA
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 33 Page(s): 1405 - 1405
    03/15/1992 Authors: BOATRIGHT JH; GORDON JR; IUVONE PM
  • MELATONIN RECEPTOR-MEDIATED INHIBITION OF DOPAMINE STIMULATED AND FORSKOLIN STIMULATED CYCLIC-AMP ACCUMULATION IN CHICK RETINAL CELL-CULTURES
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 33 Page(s): 1405 - 1405
    03/15/1992 Authors: IUVONE PM; GAN J
  • Is dopamine a light-adaptive or a dark-adaptive modulator in retina?
    Neurochem Int Volume: 20 Page(s): 193 - 199
    02/01/1992 Authors: Besharse JC; Iuvone PM
  • Melatonin synthesis in chicken retina: effect of kainic acid-induced lesions on the diurnal rhythm and D2-dopamine receptor-mediated regulation of serotonin N-acetyltransferase activity.
    Neurosci Lett Volume: 135 Page(s): 71 - 74
    01/20/1992 Authors: Zawilska JB; Iuvone PM
  • Circadian rhythm of tryptophan hydroxylase activity in chicken retina.
    Cell Mol Neurobiol Volume: 11 Page(s): 511 - 527
    10/01/1991 Authors: Thomas KB; Iuvone PM
  • K(+)-evoked depolarization stimulates cyclic AMP accumulation in photoreceptor-enriched retinal cell cultures: role of calcium influx through dihydropyridine-sensitive calcium channels.
    J Neurochem Volume: 57 Page(s): 615 - 621
    08/01/1991 Authors: Iuvone PM; Gan J; Avendano G
  • Effects of apomorphine, a dopamine receptor agonist, on ocular refraction and axial elongation in a primate model of myopia.
    Invest Ophthalmol Vis Sci Volume: 32 Page(s): 1674 - 1677
    04/01/1991 Authors: Iuvone PM; Tigges M; Stone RA; Lambert S; Laties AM
  • MDL 12,330A, AN INHIBITOR OF ADENYLATE-CYCLASE ACTIVITY, INHIBITS INDUCTION OF SEROTONIN N-ACETYLTRANSFERASE ACTIVITY IN RETINA AND PINEAL-GLAND
    FASEB JOURNAL Volume: 5 Page(s): A1499 - A1499
    03/19/1991 Authors: BOATRIGHT JH; GAN J; BUTLER BJ; AVENDANO G; IUVONE PM
  • STIMULATORY AND INHIBITORY EFFECTS OF ADENOSINE-ANALOGS ON TYROSINE-HYDROXYLASE ACTIVITY IN STRIATAL SLICES OF CONTROL AND CAFFEINE TOLERANT RATS
    FASEB JOURNAL Volume: 5 Page(s): A1574 - A1574
    03/19/1991 Authors: BUTLER BJ; ADJARESEFA A; LONG S; IUVONE PM
  • MULTIPLE INHIBITORY MODULATORS OF DOPAMINE RELEASE IN FROG RETINA
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 32 Page(s): 1261 - 1261
    03/15/1991 Authors: BOATRIGHT JH; IUVONE PM
  • MELATONIN IN KAINIC ACID-LESIONED CHICK RETINA
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 32 Page(s): 1261 - 1261
    03/15/1991 Authors: IUVONE PM; THOMAS KB; TIGGES M; ZAWILSKA JB
  • ROLE OF CYCLIC-AMP IN K+-EVOKED, CA2+-DEPENDENT INDUCTION OF SEROTONIN N-ACETYLTRANSFERASE IN PHOTORECEPTOR-ENRICHED CHICK RETINAL CELL-CULTURES
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 32 Page(s): 1265 - 1265
    03/15/1991 Authors: GAN J; AVENDANO G; BUTLER B; IUVONE PM
  • CIRCADIAN TRYPTOPHAN-HYDROXYLASE IN RETINA IS NOT ASSOCIATED WITH SEROTONIN-IMMUNOREACTIVE AMACRINE OR BIPOLAR CELLS
    FASEB JOURNAL Volume: 5 Page(s): A412 - A412
    03/11/1991 Authors: THOMAS KB; IUVONE PM
  • Alpha-2 adrenergic activity of bromocriptine and quinpirole in chicken pineal gland. Effects on melatonin synthesis and [3H]rauwolscine binding.
    J Pharmacol Exp Ther Volume: 255 Page(s): 1047 - 1052
    12/01/1990 Authors: Zawilska J; Iuvone PM
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    J Neurochem Volume: 55 Page(s): 673 - 682
    08/01/1990 Authors: Iuvone PM; Avendano G; Butler BJ; Adler R
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    Neuropharmacology Volume: 29 Page(s): 625 - 631
    07/01/1990 Authors: Finn IB; Iuvone PM; Holtzman SG
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    J Neurochem Volume: 54 Page(s): 1562 - 1568
    05/01/1990 Authors: Iuvone PM
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    Anal Biochem Volume: 184 Page(s): 228 - 234
    02/01/1990 Authors: Thomas KB; Zawilska J; Iuvone PM
  • K(+)-evoked depolarization induces serotonin N-acetyltransferase activity in photoreceptor-enriched retinal cell cultures. Involvement of calcium influx through l-type channels.
    Neurochem Int Volume: 17 Page(s): 117 - 126
    01/01/1990 Authors: Avendano G; Butler BJ; Michael Iuvone P
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    Stereotact Funct Neurosurg Volume: 54-55 Page(s): 312 - 323
    01/01/1990 Authors: Bakay RA; Watts RL; Freeman A; Iuvone PM; Watts N; Graham SD
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    Prog Brain Res Volume: 82 Page(s): 581 - 591
    01/01/1990 Authors: Watts RL; Bakay RA; Herring CJ; Sweeney KM; Colbassani HJ; Mandir A; Byrd LD; Iuvone PM
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    Ciba Found Symp Volume: 155 Page(s): 45 - 57
    01/01/1990 Authors: Stone RA; Lin T; Iuvone PM; Laties AM
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    Proc Natl Acad Sci U S A Volume: 86 Page(s): 9011 - 9014
    11/01/1989 Authors: Wolff JA; Fisher LJ; Xu L; Jinnah HA; Langlais PJ; Iuvone PM; O'Malley KL; Rosenberg MB; Shimohama S; Friedmann T
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    ANNALS OF NEUROLOGY Volume: 26 Page(s): 138 - 138
    07/01/1989 Authors: WATTS RL; KRIEG MM; FREEMAN A; MANDIR A; IUVONE PM
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    J Pharmacol Exp Ther Volume: 250 Page(s): 86 - 92
    07/01/1989 Authors: Zawilska J; Iuvone PM
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    Brain Res Volume: 482 Page(s): 164 - 168
    03/13/1989 Authors: Boatright JH; Hoel MJ; Iuvone PM
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    Vis Neurosci Volume: 2 Page(s): 465 - 471
    01/01/1989 Authors: Iuvone PM; Tigges M; Fernandes A; Tigges J
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    Proc Natl Acad Sci U S A Volume: 86 Page(s): 704 - 706
    01/01/1989 Authors: Stone RA; Lin T; Laties AM; Iuvone PM
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    Neurochem Int Volume: 15 Page(s): 541 - 547
    01/01/1989 Authors: Boatright JH; Iuvone PM
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    Neurochem Int Volume: 15 Page(s): 549 - 554
    01/01/1989 Authors: Boatright JH; Iuvone PM
  • DEVELOPMENT OF RETINAL DOPAMINE SYSTEM AND LATERAL GENICULATE-NUCLEUS (LGN) IN NORMAL AND VISUALLY DEPRIVED INFANT RHESUS-MONKEYS
    INTERNATIONAL JOURNAL OF PRIMATOLOGY Volume: 8 Page(s): 444 - 444
    10/01/1987 Authors: TIGGES M; IUVONE PM; TIGGES J; FERNANDES A; GAMMON JA
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    J Pharmacol Exp Ther Volume: 242 Page(s): 842 - 849
    09/01/1987 Authors: Johnson RD; Iuvone PM; Minneman KP
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    Brain Res Volume: 418 Page(s): 314 - 324
    08/25/1987 Authors: Iuvone PM; Boatright JH; Bloom MM
  • Biochemical and behavioral correction of MPTP Parkinson-like syndrome by fetal cell transplantation.
    Ann N Y Acad Sci Volume: 495 Page(s): 623 - 640
    01/01/1987 Authors: Bakay RA; Barrow DL; Fiandaca MS; Iuvone PM; Schiff A; Collins DC
  • Effect of tyrosine administration on dopa accumulation in light- and dark-adapted retinas from normal and diabetic rats.
    Life Sci Volume: 39 Page(s): 2049 - 2057
    12/01/1986 Authors: Fernstrom MH; Volk EA; Fernstrom JD; Iuvone PM
  • Tyrosine hydroxylase activation in mesocortical 3,4-dihydroxyphenylethylamine neurons following footshock.
    J Neurochem Volume: 47 Page(s): 837 - 844
    09/01/1986 Authors: Iuvone PM; Dunn AJ
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    Behav Brain Res Volume: 20 Page(s): 231 - 240
    05/01/1986 Authors: Brackett NL; Iuvone PM; Edwards DA
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    Brain Res Volume: 369 Page(s): 168 - 176
    03/26/1986 Authors: Iuvone PM; Besharse JC
  • Evidence for a D2 dopamine receptor in frog retina that decreases cyclic AMP accumulation and serotonin N-acetyltransferase activity.
    Life Sci Volume: 38 Page(s): 331 - 342
    01/27/1986 Authors: Iuvone PM
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    J Neurochem Volume: 46 Page(s): 82 - 88
    01/01/1986 Authors: Iuvone PM; Besharse JC
  • Cyclic AMP stimulates serotonin N-acetyltransferase activity in Xenopus retina in vitro.
    J Neurochem Volume: 46 Page(s): 33 - 39
    01/01/1986 Authors: Iuvone PM; Besharse JC
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    Brain Res Volume: 359 Page(s): 392 - 396
    12/16/1985 Authors: Iuvone PM; Reinhard JF; Abou-Donia MM; Viveros OH; Nichol CA
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    J Neurochem Volume: 43 Page(s): 1359 - 1368
    11/01/1984 Authors: Iuvone PM
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    Fed Proc Volume: 43 Page(s): 2704 - 2708
    09/01/1984 Authors: Besharse JC; Dunis DA; Iuvone PM
  • Regulation of retinal dopamine biosynthesis and tyrosine hydroxylase activity by light.
    Fed Proc Volume: 43 Page(s): 2709 - 2713
    09/01/1984 Authors: Iuvone PM
  • Catecholamines and indoleamines in retina. Introduction.
    Fed Proc Volume: 43 Page(s): 2697 - 2698
    09/01/1984 Authors: Iuvone PM
  • Alpha 2-adrenergic receptors influence tyrosine hydroxylase activity in retinal dopamine neurons.
    Life Sci Volume: 33 Page(s): 2455 - 2463
    12/12/1983 Authors: Iuvone PM; Rauch AL
  • Short-term regulation of tyrosine hydroxylase in tonically-active and in tonically-inactive dopamine neurons: effects of haloperidol and protein phosphorylation.
    Life Sci Volume: 33 Page(s): 1315 - 1324
    09/26/1983 Authors: Iuvone PM
  • Circadian clock in Xenopus eye controlling retinal serotonin N-acetyltransferase.
    Nature Volume: 305 Page(s): 133 - 135
    09/08/1983 Authors: Besharse JC; Iuvone PM
  • Regulation of indoleamine N-acetyltransferase activity in the retina: effects of light and dark, protein synthesis inhibitors and cyclic nucleotide analogs.
    Brain Res Volume: 273 Page(s): 111 - 119
    08/22/1983 Authors: Iuvone PM; Besharse JC
  • ACTIVATION OF STRIATAL TYROSINE-HYDROXYLASE BY CALCIUM, ATP, AND MAGNESIUM - POSSIBLE INVOLVEMENT OF ENDOGENOUS CALCIUM-DEPENDENT, PHOSPHOLIPID-SENSITIVE PROTEIN-KINASE
    FEDERATION PROCEEDINGS Volume: 42 Page(s): 379 - 379
    01/01/1983 Authors: IUVONE PM; BUTLER BKJ
  • Activation of retinal tyrosine hydroxylase in vitro by cyclic AMP-dependent protein kinase: characterization and comparison to activation in vivo by photic stimulation.
    J Neurochem Volume: 39 Page(s): 1632 - 1640
    12/01/1982 Authors: Iuvone PM; Rauch AL; Marshburn PB; Glass DB; Neff NH
  • Regulation of tyrosine hydroxylase activity in retinal cell suspensions: effects of potassium and 8-bromo cyclic AMP.
    Life Sci Volume: 30 Page(s): 85 - 91
    01/04/1982 Authors: Iuvone PM; Marshburn PB
  • PHOTORECEPTOR DISK SHEDDING - POSSIBLE REGULATION OF CELL-CELL INTERACTION BY LOCALLY PRODUCED METHOXYINDOLES
    JOURNAL OF CELL BIOLOGY Volume: 95 Page(s): A10 - A10
    01/01/1982 Authors: DUNIS DA; IUVONE PM; BESHARSE JC
  • Neuroleptic drugs activate tyrosine hydroxylase of retinal amacrine cells.
    J Pharmacol Exp Ther Volume: 218 Page(s): 390 - 394
    08/01/1981 Authors: Cohen J; Iuvone PM; Neff NH
  • The role of GABA in the regulation of the dopamine/tyrosine hydroxylase-containing neurons of the rat retina.
    Brain Res Volume: 214 Page(s): 335 - 347
    06/15/1981 Authors: Marshburn PB; Iuvone PM
  • Dopamine neurons of the retina: a simple method system for studying synaptic regulatory mechanisms.
    Essays Neurochem Neuropharmacol Volume: 5 Page(s): 75 - 94
    01/01/1981 Authors: Iuvone PM; Neff NH
  • ACTIVATION OF TYROSINE-HYDROXYLASE IN RETINA AND VENTRAL TEGMENTAL AREA OF BRAIN FOLLOWING REPEATED ADMINISTRATION OF ANTIPSYCHOTIC-DRUGS
    FEDERATION PROCEEDINGS Volume: 40 Page(s): 300 - 300
    01/01/1981 Authors: IUVONE PM; RAUCH AL
  • Evidence that TRH, somatostatin and substance P are present in neuro-secretory elements of the vertebrate retina.
    Brain Res Volume: 196 Page(s): 554 - 559
    09/08/1980 Authors: Eskay RL; Long RT; Iuvone PM
  • Regulation of retinal tyrosine hydroxylase: long-term exposure to light increased the apparent Vmax without a concomitant increase of immunotitratable enzyme molecules.
    Brain Res Volume: 178 Page(s): 191 - 195
    12/07/1979 Authors: Iuvone PM; Joh TH; Neff NH
  • Corticotrophin increases cerebral polyamine content.
    J Neurochem Volume: 33 Page(s): 1067 - 1073
    11/01/1979 Authors: Tintner R; Dunn AJ; Iuvone PM; Shukla JB; Rennert OM
  • Light stimulates tyrosine hydroxylase activity and dopamine synthesis in retinal amacrine neurons.
    Science Volume: 202 Page(s): 901 - 902
    11/24/1978 Authors: Iuvone PM; Galli CL; Garrison-Gund CK; Neff NH
  • Retinal tyrosine hydroxylase: comparison of short-term and long-term stimulation by light.
    Mol Pharmacol Volume: 14 Page(s): 1212 - 1219
    11/01/1978 Authors: Iuvone PM; Galli CL; Neff NH
  • ACTH and the stress-induced changes of lysine incorporation into brain and liver proteins.
    Pharmacol Biochem Behav Volume: 8 Page(s): 455 - 465
    04/01/1978 Authors: Dunn AJ; Rees HD; Iuvone PM
  • Peptides and the conversion of [3H]tyrosine to catecholamines: effects of ACTH-analogs, melanocyte-stimulating hormones and lysine-vasopressin.
    Brain Res Volume: 139 Page(s): 131 - 139
    01/06/1978 Authors: Iuvone PM; Morasco J; Delanoy RL; Dunn AJ
  • Pentylenetetrazol: inhibitory avoidance behavior, brain seizure activity, and [3H]lysine incorporation into brain proteins of different mouse strains.
    Behav Biol Volume: 21 Page(s): 236 - 250
    10/01/1977 Authors: Iuvone PM; Boast CA; Gray HE; Dunn AJ
  • Diurnal locomotor activity in rats: effects of hippocampal ablation and adrenalectomy.
    Behav Biol Volume: 19 Page(s): 228 - 237
    02/01/1977 Authors: Iuvone PM; Van Hartesveldt C
  • Effect of corticosterone on the synthesis of [3H]catecholamines in the brains of CD-1 mice.
    Brain Res Volume: 120 Page(s): 571 - 576
    01/28/1977 Authors: Iuvone PM; Morasco J; Dunn AJ
  • Protein synthesis and amnesia: studies with emetine and pactamycin.
    Pharmacol Biochem Behav Volume: 6 Page(s): 1 - 4
    01/01/1977 Authors: Dunn AJ; Gray HE; Iuvone PM
  • Behavioral and biochemical responses of mice to the intraventricular administration of ACTH analogs and lysine vasopressin.
    Life Sci Volume: 18 Page(s): 1333 - 1339
    06/01/1976 Authors: Rees HD; Dunn AJ; Iuvone PM
  • Locomotor activity and plasma corticosterone in rats with hippocampal lesions.
    Behav Biol Volume: 16 Page(s): 515 - 520
    04/01/1976 Authors: Iuvone PM; Van Hartesveldt C
  • Neurochemical responses of mice to ACTH and lysine vasopressin.
    Pharmacol Biochem Behav Volume: 5 Page(s): 139 - 145
    01/01/1976 Authors: Dunn AJ; Iuvone PM; Rees HD
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