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Profile

Marla Gearing PhD

  • Department of Pathology and Laboratory Medicine
    Associate Professor
  • (404) 712-8352
  • mgearin@emory.edu
Head shot of Marla Gearing

Academic Appointment

  • Assistant Professor, Department of Pathology and Laboratory Medicine, Emory University School of Medicine

Education

Degrees

  • PhD from The University of Wisconsin
  • BS from Cornell University
  • Master of Science from Emory University

Research

Focus

  • a. Overlap among neurodegenerative diseases b. Regional differences in neuropathologic changes, both within a disease (e.g., neurofibrillary tangles and -amyloid deposition in Alzheimers disease) and among different neurodegenerative diseases (e.g., neurofibrillary tangles in Alzheimers disease vs. progressive supranuclear palsy) c. Neuropathologic changes in aged nonhuman primates and other animals

Publications

  • Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing.
    Nat Commun Volume: 16 Page(s): 3914
    04/25/2025 Authors: Pottier C; Kkali F; Baker M; Batzler A; Jenkins GD; van Blitterswijk M; Vicente CT; De Coster W; Wynants S; Van de Walle P
  • ALS plasma biomarkers reveal neurofilament and pTau correlate with disease onset and progression.
    Ann Clin Transl Neurol Volume: 12 Page(s): 714 - 723
    04/01/2025 Authors: Thomas EV; Han C; Kim WJ; Asress S; Li Y; Taylor JA; Gearing M; Fournier CN; McEachin ZT; Seyfried NT
  • Copy Number Variation and Haplotype Analysis of 17q21.31 Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells.
    Mov Disord
    03/08/2025 Authors: Wang H; Chang TS; Dombroski BA; Cheng P-L; Si Y-Q; Tucci A; Patil V; Valiente-Banuet L; Li C; Farrell K
  • pTDP-43 levels correlate with cell type-specific molecular alterations in the prefrontal cortex of C9orf72 ALS/FTD patients.
    Proc Natl Acad Sci U S A Volume: 122 Page(s): e2419818122
    03/04/2025 Authors: Wang H-LV; Xiang J-F; Yuan C; Veire AM; Gendron TF; Murray ME; Tansey MG; Hu J; Gearing M; Glass JD
  • Large-scale deep proteomic analysis in Alzheimer's disease brain regions across race and ethnicity.
    Alzheimers Dement Volume: 20 Page(s): 8878 - 8897
    12/01/2024 Authors: Seifar F; Fox EJ; Shantaraman A; Liu Y; Dammer EB; Modeste E; Duong DM; Yin L; Trautwig AN; Guo Q
  • Correction: Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsy.
    Mol Neurodegener Volume: 19 Page(s): 73
    10/14/2024 Authors: Wang H; Chang TS; Dombroski BA; Cheng P-L; Patil V; Valiente-Banuet L; Farrell K; Mclean C; Molina-Porcel L; Rajput A
  • Correction: Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease.
    Mol Neurodegener Volume: 19 Page(s): 71
    10/11/2024 Authors: Shantaraman A; Dammer EB; Ugochukwu O; Duong DM; Yin L; Carter EK; Gearing M; Chen-Plotkin A; Lee EB; Trojanowski JQ
  • Bridging the gap: Multi-omics profiling of brain tissue in Alzheimer's disease and older controls in multi-ethnic populations.
    Alzheimers Dement Volume: 20 Page(s): 7174 - 7192
    10/01/2024 Authors: Reddy JS; Heath L; Linden AV; Allen M; Lopes KDP; Seifar F; Wang E; Ma Y; Poehlman WL; Quicksall ZS
  • Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsy.
    Mol Neurodegener Volume: 19 Page(s): 61
    08/16/2024 Authors: Wang H; Chang TS; Dombroski BA; Cheng P-L; Patil V; Valiente-Banuet L; Farrell K; Mclean C; Molina-Porcel L; Rajput A
  • Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease.
    Mol Neurodegener Volume: 19 Page(s): 60
    08/06/2024 Authors: Shantaraman A; Dammer EB; Ugochukwu O; Duong DM; Yin L; Carter EK; Gearing M; Chen-Plotkin A; Lee EB; Trojanowski JQ
  • Deciphering Distinct Genetic Risk Factors for FTLD-TDP Pathological Subtypes via Whole-Genome Sequencing.
    medRxiv
    06/25/2024 Authors: Pottier C; Kkali F; Baker M; Batzler A; Jenkins GD; van Blitterswijk M; Vicente CT; De Coster W; Wynants S; Van de Walle P
  • pTDP-43 levels correlate with cell type specific molecular alterations in the prefrontal cortex of C9orf72 ALS/FTD patients.
    bioRxiv
    06/13/2024 Authors: Wang H-LV; Xiang J-F; Yuan C; Veire AM; Gendron TF; Murray ME; Tansey MG; Hu J; Gearing M; Glass JD
  • MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study.
    Lancet Neurol Volume: 23 Page(s): 487 - 499
    05/01/2024 Authors: Valentino RR; Scotton WJ; Roemer SF; Lashley T; Heckman MG; Shoai M; Martinez-Carrasco A; Tamvaka N; Walton RL; Baker MC
  • Large-scale Deep Proteomic Analysis in Alzheimer's Disease Brain Regions Across Race and Ethnicity.
    bioRxiv
    04/26/2024 Authors: Seifar F; Fox EJ; Shantaraman A; Liu Y; Dammer EB; Modeste E; Duong DM; Yin L; Trautwig AN; Guo Q
  • The association between neighborhood deprivation and DNA methylation in an autopsy cohort.
    Aging (Albany NY) Volume: 16 Page(s): 6694 - 6716
    04/24/2024 Authors: Pett L; Li Z; Abrishamcar S; Hodge K; Everson T; Christensen G; Gearing M; Kobor MS; Konwar C; MacIsaac JL
  • Bridging the Gap: Multi-Omics Profiling of Brain Tissue in Alzheimer's Disease and Older Controls in Multi-Ethnic Populations.
    bioRxiv
    04/20/2024 Authors: Reddy JS; Heath L; Vander Linden A; Allen M; de Paiva Lopes K; Seifar F; Wang E; Ma Y; Poehlman WL; Quicksall ZS
  • Vascular Heparan Sulfate and Amyloid- in Alzheimer's Disease Patients.
    Int J Mol Sci Volume: 25
    04/02/2024 Authors: McMillan IO; Gearing M; Wang L
  • Differential DNA methylation in the brain as potential mediator of the association between traffic-related PM2.5 and neuropathology markers of Alzheimer's disease.
    Alzheimers Dement Volume: 20 Page(s): 2538 - 2551
    04/01/2024 Authors: Li Z; Liang D; Ebelt S; Gearing M; Kobor MS; Konwar C; Maclsaac JL; Dever K; Wingo AP; Levey AI
  • Association of PM2.5 Exposure and Alzheimer Disease Pathology in Brain Bank Donors-Effect Modification by APOE Genotype.
    Neurology Volume: 102 Page(s): e209162
    03/12/2024 Authors: Christensen GM; Li Z; Liang D; Ebelt S; Gearing M; Levey AI; Lah JJ; Wingo A; Wingo T; Hls A
  • Association of Structural Forms of 17q21.31 with the Risk of Progressive Supranuclear Palsy and MAPT Sub-haplotypes.
    medRxiv
    02/28/2024 Authors: Wang H; Chang TS; Dombroski BA; Cheng P-L; Si Y-Q; Tucci A; Patil V; Valiente-Banuet L; Farrell K; Mclean C
  • Whole-Genome Sequencing Analysis Reveals New Susceptibility Loci and Structural Variants Associated with Progressive Supranuclear Palsy.
    medRxiv
    01/30/2024 Authors: Wang H; Chang TS; Dombroski BA; Cheng P-L; Patil V; Valiente-Banuet L; Farrell K; Mclean C; Molina-Porcel L; Rajput A
  • Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease.

    01/24/2024 Authors: Shantaraman A; Dammer EB; Ugochukwu O; Duong DM; Yin L; Carter EK; Gearing M; Chen-Plotkin A; Lee EB; Trojanowski JQ
  • Toward a generalizable machine learning workflow for neurodegenerativedisease staging with focus on neurofibrillary tangles.
    Acta Neuropathol Commun Volume: 11 Page(s): 202
    12/18/2023 Authors: Vizcarra JC; Pearce TM; Dugger BN; Keiser MJ; Gearing M; Crary JF; Kiely EJ; Morris M; White B; Glass JD
  • Ancestry-related differences in chromatin accessibility and gene expression of APOE 4 are associated with Alzheimer's disease risk.
    Alzheimers Dement Volume: 19 Page(s): 3902 - 3915
    09/01/2023 Authors: Celis K; Moreno MDMM; Rajabli F; Whitehead P; Hamilton-Nelson K; Dykxhoorn DM; Nuytemans K; Wang L; Flanagan M; Weintraub S
  • Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.
    medRxiv
    07/08/2023 Authors: Rajabli F; Benchek P; Tosto G; Kushch N; Sha J; Bazemore K; Zhu C; Lee W-P; Haut J; Hamilton-Nelson KL
  • Differential DNA Methylation in the Brain as Potential Mediator of the Association between Traffic-related PM2.5 and Neuropathology Markers of Alzheimer's Disease.
    medRxiv
    06/30/2023 Authors: Li Z; Liang D; Ebelt S; Gearing M; Kobor MS; Konwar C; Maclsaac JL; Dever K; Wingo A; Levey A
  • Increased 3-O-sulfated heparan sulfate in Alzheimer's disease brain is associated with genetic risk gene HS3ST1.
    Sci Adv Volume: 9 Page(s): eadf6232
    05/26/2023 Authors: Wang Z; Patel VN; Song X; Xu Y; Kaminski AM; Doan VU; Su G; Liao Y; Mah D; Zhang F
  • Cross-Platform Synaptic Network Analysis of Human Entorhinal Cortex Identifies TWF2 as a Modulator of Dendritic Spine Length.
    J Neurosci Volume: 43 Page(s): 3764 - 3785
    05/17/2023 Authors: Walker CK; Greathouse KM; Tuscher JJ; Dammer EB; Weber AJ; Liu E; Curtis KA; Boros BD; Freeman CD; Seo JV
  • MicroRNA-650 Regulates the Pathogenesis of Alzheimer's Disease Through Targeting Cyclin-Dependent Kinase 5.
    Mol Neurobiol Volume: 60 Page(s): 2426 - 2441
    05/01/2023 Authors: Lin L; Liu X; Cheng X; Li Y; Gearing M; Levey A; Huang X; Li Y; Jin P; Li X
  • Creating the Pick's disease International Consortium: Association study of MAPT H2 haplotype with risk of Pick's disease.
    medRxiv
    04/24/2023 Authors: Valentino RR; Scotton WJ; Roemer SF; Lashley T; Heckman MG; Shoai M; Martinez-Carrasco A; Tamvaka N; Walton RL; Baker MC
  • Fine particulate air pollution and neuropathology markers of Alzheimer's disease in donors with and without APOE 4 alleles - results from an autopsy cohort.
    medRxiv
    04/07/2023 Authors: Christensen GM; Li Z; Liang D; Ebelt S; Gearing M; Levey AI; Lah JJ; Wingo AP; Wingo TS; Huels A
  • Medin co-aggregates with vascular amyloid- in Alzheimer's disease.
    Nature Volume: 612 Page(s): 123 - 131
    12/01/2022 Authors: Wagner J; Degenhardt K; Veit M; Louros N; Konstantoulea K; Skodras A; Wild K; Liu P; Obermller U; Bansal V
  • Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.
    Mov Disord Volume: 37 Page(s): 2110 - 2121
    10/01/2022 Authors: Hopfner F; Tietz AK; Ruf VC; Ross OA; Koga S; Dickson D; Aguzzi A; Attems J; Beach T; Beller A
  • Interpretable deep learning of myelin histopathology in age-related cognitive impairment.
    Acta Neuropathol Commun Volume: 10 Page(s): 131
    09/21/2022 Authors: McKenzie AT; Marx GA; Koenigsberg D; Sawyer M; Iida MA; Walker JM; Richardson TE; Campanella G; Attems J; McKee AC
  • An early proinflammatory transcriptional response to tau pathology is age-specific and foreshadows reduced tau burden.
    Brain Pathol Volume: 32 Page(s): e13018
    05/01/2022 Authors: Rasmussen J; Ewing AD; Bodea L-G; Bodea GO; Gearing M; Faulkner GJ
  • Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.
    Sci Rep Volume: 12 Page(s): 6117
    04/12/2022 Authors: Heath L; Earls JC; Magis AT; Kornilov SA; Lovejoy JC; Funk CC; Rappaport N; Logsdon BA; Mangravite LM; Kunkle BW
  • New insights into the genetic etiology of Alzheimer's disease and related dementias.
    Nat Genet Volume: 54 Page(s): 412 - 436
    04/01/2022 Authors: Bellenguez C; Kkali F; Jansen IE; Kleineidam L; Moreno-Grau S; Amin N; Naj AC; Campos-Martin R; Grenier-Boley B; Andrade V
  • Correction to Analysis of 3-O-Sulfated Heparan Sulfate Using Isotopically Labeled Oligosaccharide Calibrants.
    Anal Chem Volume: 94 Page(s): 4134
    03/08/2022 Authors: Wang Z; Arnold K; Dhurandhare VM; Xu Y; Pagadala V; Labra E; Jeske W; Fareed J; Gearing M; Liu J
  • Analysis of 3-O-Sulfated Heparan Sulfate Using Isotopically Labeled Oligosaccharide Calibrants.
    Anal Chem Volume: 94 Page(s): 2950 - 2957
    02/15/2022 Authors: Wang Z; Arnold K; Dhurandahare VM; Xu Y; Pagadala V; Labra E; Jeske W; Fareed J; Gearing M; Liu J
  • Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level.
    Nat Neurosci Volume: 25 Page(s): 213 - 225
    02/01/2022 Authors: Johnson ECB; Carter EK; Dammer EB; Duong DM; Gerasimov ES; Liu Y; Liu J; Betarbet R; Ping L; Yin L
  • Genome-wide association study and functional validation implicates JADE1 in tauopathy.
    Acta Neuropathol Volume: 143 Page(s): 33 - 53
    01/01/2022 Authors: Farrell K; Kim S; Han N; Iida MA; Gonzalez EM; Otero-Garcia M; Walker JM; Richardson TE; Renton AE; Andrews SJ
  • Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level.
    Alzheimers Dement Volume: 17 Suppl 3 Page(s): e055041
    12/01/2021 Authors: Johnson ECB; Carter EK; Dammer EB; Duong DM; Liu Y; Liu J; Betarbet R; Ping L; Yin L; Beach TG
  • Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study.
    Acta Neuropathol Commun Volume: 9 Page(s): 134
    08/05/2021 Authors: Iida MA; Farrell K; Walker JM; Richardson TE; Marx GA; Bryce CH; Purohit D; Ayalon G; Beach TG; Bigio EH
  • GPR37 modulates progenitor cell dynamics in a mouse model of ischemic stroke.
    Exp Neurol Volume: 342 Page(s): 113719
    08/01/2021 Authors: Owino S; Giddens MM; Jiang JG; Nguyen TT; Shiu FH; Lala T; Gearing M; McCrary MR; Gu X; Wei L
  • Increased APOE 4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds.
    Alzheimers Dement Volume: 17 Page(s): 1179 - 1188
    07/01/2021 Authors: Griswold AJ; Celis K; Bussies PL; Rajabli F; Whitehead PL; Hamilton-Nelson KL; Beecham GW; Dykxhoorn DM; Nuytemans K; Wang L
  • Quantification and Staging of Neurofibrillary Degeneration Using Deep Learning
    Volume: 80 Page(s): 596 - 596
    06/01/2021 Authors: Vizcarra J; White B; Crary J; Gearing M; Keiser M; Farrell K; Schock B; Dugger B; Gutman D
  • Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy.
    J Neuropathol Exp Neurol Volume: 80 Page(s): 102 - 111
    01/20/2021 Authors: Walker JM; Richardson TE; Farrell K; Iida MA; Foong C; Shang P; Attems J; Ayalon G; Beach TG; Bigio EH
  • TBK1 interacts with tau and enhances neurodegeneration in tauopathy.
    J Biol Chem Volume: 296 Page(s): 100760
    01/01/2021 Authors: Abreha MH; Ojelade S; Dammer EB; McEachin ZT; Duong DM; Gearing M; Bassell GJ; Lah JJ; Levey AI; Shulman JM
  • Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer's Disease.
    Front Mol Neurosci Volume: 14 Page(s): 623659
    01/01/2021 Authors: Guo Q; Dammer EB; Zhou M; Kundinger SR; Gearing M; Lah JJ; Levey AI; Shulman JM; Seyfried NT
  • Fibrillation and molecular characteristics are coherent with clinical and pathological features of 4-repeat tauopathy caused by MAPT variant G273R.
    Neurobiol Dis Volume: 146 Page(s): 105079
    12/01/2020 Authors: Sandberg A; Ling H; Gearing M; Dombroski B; Cantwell L; R'Bibo L; Levey A; Schellenberg GD; Hardy J; Wood N
  • Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations.
    Acta Neuropathol Commun Volume: 8 Page(s): 163
    10/07/2020 Authors: Huang M; Modeste E; Dammer E; Merino P; Taylor G; Duong DM; Deng Q; Holler CJ; Gearing M; Dickson D
  • Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease.
    Sci Adv Volume: 6
    10/01/2020 Authors: Higginbotham L; Ping L; Dammer EB; Duong DM; Zhou M; Gearing M; Hurst C; Glass JD; Factor SA; Johnson ECB
  • Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease.
    Sci Data Volume: 7 Page(s): 315
    09/28/2020 Authors: Ping L; Kundinger SR; Duong DM; Yin L; Gearing M; Lah JJ; Levey AI; Seyfried NT
  • Tau deposition in the spinal cord is not specific for CTE-ALS.
    Neurology Volume: 95 Page(s): 37 - 39
    07/07/2020 Authors: Fournier CN; Gearing M; Glass JD
  • Cross-institution validation of machine learning algorithms assessing amyloid pathologies in Alzheimer's disease
    Volume: 79 Page(s): 662 - 663
    06/01/2020 Authors: Vizcarra J; Gearing M; Keiser M; Dugger B; Gutman D
  • Validation of machine learning models to detect amyloid pathologies across institutions.
    Acta Neuropathol Commun Volume: 8 Page(s): 59
    04/28/2020 Authors: Vizcarra JC; Gearing M; Keiser MJ; Glass JD; Dugger BN; Gutman DA
  • Transcriptome Analysis of Single Nucleus RNA-seq from Alzheimer Disease APOE4 Carrier Brains in African American (AA) and Non-Hispanic Whites (NHW) Reveals Differences in APOE Expression
    Volume: 94
    04/14/2020 Authors: Celis K; Griswold AJ; Bussies PL; Rajabli F; Whitehead P; Dorfsman D; Hamilton-Nelson K; Bigio E; Mesulam M; Geula C
  • Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
    Nat Commun Volume: 11 Page(s): 667
    02/03/2020 Authors: Reiman EM; Arboleda-Velasquez JF; Quiroz YT; Huentelman MJ; Beach TG; Caselli RJ; Chen Y; Su Y; Myers AJ; Hardy J
  • Histological Confirmation of Myelinated Neural Filaments Within the Tip of the Neurotrophic Electrode After a Decade of Neural Recordings.
    Front Hum Neurosci Volume: 14 Page(s): 111
    01/01/2020 Authors: Gearing M; Kennedy P
  • C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy.
    Acta Neuropathol Volume: 138 Page(s): 795 - 811
    11/01/2019 Authors: Cali CP; Patino M; Tai YK; Ho WY; McLean CA; Morris CM; Seeley WW; Miller BL; Gaig C; Vonsattel JPG
  • Interleukin 9 alterations linked to alzheimer disease in african americans.
    Ann Neurol Volume: 86 Page(s): 407 - 418
    09/01/2019 Authors: Wharton W; Kollhoff AL; Gangishetti U; Verble DD; Upadhya S; Zetterberg H; Kumar V; Watts KD; Kippels AJ; Gearing M
  • Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype.
    JAMA Neurol Volume: 76 Page(s): 1099 - 1108
    09/01/2019 Authors: Ma Y; Jun GR; Zhang X; Chung J; Naj AC; Chen Y; Bellenguez C; Hamilton-Nelson K; Martin ER; Kunkle BW
  • Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A, tau, immunity and lipid processing.
    Nat Genet Volume: 51 Page(s): 1423 - 1424
    09/01/2019 Authors: Kunkle BW; Grenier-Boley B; Sims R; Bis JC; Damotte V; Naj AC; Boland A; Vronskaya M; van der Lee SJ; Amlie-Wolf A
  • Pro-Nerve Growth Factor Induces Activation of RhoA Kinase and Neuronal Cell Death.
    Brain Sci Volume: 9
    08/19/2019 Authors: Sycheva M; Sustarich J; Zhang Y; Selvaraju V; Geetha T; Gearing M; Babu JR
  • Dementia in ALS: the role of the cerebellum
    Volume: 78 Page(s): 520 - 521
    06/01/2019 Authors: Lowder L; Asress S; Dammer E; Vizcarra JC; Duc D; Goodman A; Bagchi P; Gearing M; Gutman D; Seyfried N
  • Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.
    Acta Neuropathol Volume: 137 Page(s): 879 - 899
    06/01/2019 Authors: Pottier C; Ren Y; Perkerson RB; Baker M; Jenkins GD; van Blitterswijk M; DeJesus-Hernandez M; van Rooij JGJ; Murray ME; Christopher E
  • Viscoelastic Properties of Human Autopsy Brain Tissues as Biomarkers for Alzheimer's Diseases.
    IEEE Trans Biomed Eng Volume: 66 Page(s): 1705 - 1713
    06/01/2019 Authors: Kihan Park; Lonsberry GE; Gearing M; Levey AI; Desai JP
  • TDP-43 cytoplasmic inclusion formation in C9orf72-associated FTLD/ALS
    Volume: 92
    04/09/2019 Authors: Lee S; Asress S; Hales C; Vizcarra J; Gutman D; Gearing M; Chin L-S; Li L; Glass J
  • Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A, tau, immunity and lipid processing.
    Nat Genet Volume: 51 Page(s): 414 - 430
    03/01/2019 Authors: Kunkle BW; Grenier-Boley B; Sims R; Bis JC; Damotte V; Naj AC; Boland A; Vronskaya M; van der Lee SJ; Amlie-Wolf A
  • A statistical framework for cross-tissue transcriptome-wide association analysis.
    Nat Genet Volume: 51 Page(s): 568 - 576
    03/01/2019 Authors: Hu Y; Li M; Lu Q; Weng H; Wang J; Zekavat SM; Yu Z; Li B; Gu J; Muchnik S
  • Dendritic spine remodeling accompanies Alzheimer's disease pathology and genetic susceptibility in cognitively normal aging.
    Neurobiol Aging Volume: 73 Page(s): 92 - 103
    01/01/2019 Authors: Boros BD; Greathouse KM; Gearing M; Herskowitz JH
  • TDP-43 cytoplasmic inclusion formation is disrupted in C9orf72-associated amyotrophic lateral sclerosis/frontotemporal lobar degeneration.
    Brain Commun Volume: 1 Page(s): fcz014
    01/01/2019 Authors: Lee SM; Asress S; Hales CM; Gearing M; Vizcarra JC; Fournier CN; Gutman DA; Chin L-S; Li L; Glass JD
  • Neurofibrillary Tangles and Conversion to Mild Cognitive Impairment with Certain Antihypertensives.
    J Alzheimers Dis Volume: 70 Page(s): 153 - 161
    01/01/2019 Authors: Wharton W; Zhao L; Steenland K; Goldstein FC; Schneider JA; Barnes LL; Gearing M; Yasar S
  • Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders.
    Alzheimer Dis Assoc Disord Volume: 33 Page(s): 327 - 330
    01/01/2019 Authors: Ayer AH; Wojta K; Ramos EM; Dokuru D; Chen JA; Karydas AM; Papatriantafyllou JD; Agiomyrgiannakis D; Kamtsadeli V; Tsinia N
  • Sex-specific genetic predictors of Alzheimer's disease biomarkers.
    Acta Neuropathol Volume: 136 Page(s): 857 - 872
    12/01/2018 Authors: Deming Y; Dumitrescu L; Barnes LL; Thambisetty M; Kunkle B; Gifford KA; Bush WS; Chibnik LB; Mukherjee S; De Jager PL
  • Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease.
    Proteomics Volume: 18 Page(s): e1800108
    10/01/2018 Authors: Abreha MH; Dammer EB; Ping L; Zhang T; Duong DM; Gearing M; Lah JJ; Levey AI; Seyfried NT
  • Establishing a Roadmap for Brain-Based Protein Biomarkers in Alzheimer's Disease
    Volume: 84 Page(s): S165 - S166
    10/01/2018 Authors: Zhou M; Duong DM; Ping L; Dammer EB; Gearing M; Lah JJ; Levey AI; Seyfried NT
  • The anti-parkinsonian drug zonisamide reduces neuroinflammation: Role of microglial Nav 1.6.
    Exp Neurol Volume: 308 Page(s): 111 - 119
    10/01/2018 Authors: Hossain MM; Weig B; Reuhl K; Gearing M; Wu L-J; Richardson JR
  • Effects of APOE Genotype on Protein Co-Expression in Alzheimer's Disease
    Volume: 84 Page(s): S164 - S164
    10/01/2018 Authors: Dammer EB; Dai J; Johnson ECB; Duong DM; Gearing M; Lah JJ; Levey AI; Wingo TS; Seyfried NT
  • Comprehensive Mapping of Alzheimer's Disease Brain Ubiquitin Pattern Revealed Novel Tau Ubiquitylation Sites
    Volume: 84 Page(s): S65 - S65
    10/01/2018 Authors: Abreha M; Dammer E; Ping L; Duc D; Gearing M; Lah J; Levey A; Seyfried N
  • Reader response: Pathologic Thr175 tau phosphorylation in CTE and CTE with ALS.
    Neurology Volume: 91 Page(s): 578 - 579
    09/18/2018 Authors: Glass JD; Fournier CN; Gearing M
  • Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.
    JAMA Neurol Volume: 75 Page(s): 989 - 998
    08/01/2018 Authors: Hohman TJ; Dumitrescu L; Barnes LL; Thambisetty M; Beecham G; Kunkle B; Gifford KA; Bush WS; Chibnik LB; Mukherjee S
  • RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.
    J Biol Chem Volume: 293 Page(s): 11047 - 11066
    07/13/2018 Authors: Bishof I; Dammer EB; Duong DM; Kundinger SR; Gearing M; Lah JJ; Levey AI; Seyfried NT
  • Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.
    Lancet Neurol Volume: 17 Page(s): 548 - 558
    06/01/2018 Authors: Pottier C; Zhou X; Perkerson RB; Baker M; Jenkins GD; Serie DJ; Ghidoni R; Benussi L; Binetti G; Lpez de Munain A
  • Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease.
    Sci Data Volume: 5 Page(s): 180036
    03/13/2018 Authors: Ping L; Duong DM; Yin L; Gearing M; Lah JJ; Levey AI; Seyfried NT
  • Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer's disease.
    Acta Neuropathol Commun Volume: 6 Page(s): 19
    03/01/2018 Authors: Zhang Q; Ma C; Gearing M; Wang PG; Chin L-S; Li L
  • TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD.
    Nat Neurosci Volume: 21 Page(s): 228 - 239
    02/01/2018 Authors: Chou C-C; Zhang Y; Umoh ME; Vaughan SW; Lorenzini I; Liu F; Sayegh M; Donlin-Asp PG; Chen YH; Duong DM
  • Cerebral Amyloid Angiopathy: Similarity in African-Americans and Caucasians with Alzheimer's Disease.
    J Alzheimers Dis Volume: 62 Page(s): 1815 - 1826
    01/01/2018 Authors: Kamara DM; Gangishetti U; Gearing M; Willis-Parker M; Zhao L; Hu WT; Walker LC
  • A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain.
    EMBO Mol Med Volume: 10 Page(s): 48 - 62
    01/01/2018 Authors: Umoh ME; Dammer EB; Dai J; Duong DM; Lah JJ; Levey AI; Gearing M; Glass JD; Seyfried NT
  • Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease.
    Alzheimers Dement (Amst) Volume: 10 Page(s): 595 - 598
    01/01/2018 Authors: Peloso GM; van der Lee SJ; International Genomics of Alzheimer's Project (IGAP); Destefano AL; Seshardi S
  • Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease.
    Front Mol Neurosci Volume: 11 Page(s): 454
    01/01/2018 Authors: Dai J; Johnson ECB; Dammer EB; Duong DM; Gearing M; Lah JJ; Levey AI; Wingo TS; Seyfried NT
  • Generation of Clickable Pittsburgh Compound B for the Detection and Capture of -Amyloid in Alzheimer's Disease Brain.
    Bioconjug Chem Volume: 28 Page(s): 2627 - 2637
    10/18/2017 Authors: Diner I; Dooyema J; Gearing M; Walker LC; Seyfried NT
  • Dendritic spines provide cognitive resilience against Alzheimer's disease.
    Ann Neurol Volume: 82 Page(s): 602 - 614
    10/01/2017 Authors: Boros BD; Greathouse KM; Gentry EG; Curtis KA; Birchall EL; Gearing M; Herskowitz JH
  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
    Nat Genet Volume: 49 Page(s): 1373 - 1384
    09/01/2017 Authors: Sims R; van der Lee SJ; Naj AC; Bellenguez C; Badarinarayan N; Jakobsdottir J; Kunkle BW; Boland A; Raybould R; Bis JC
  • Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
    Alzheimers Dement Volume: 13 Page(s): 727 - 738
    07/01/2017 Authors: Jun GR; Chung J; Mez J; Barber R; Beecham GW; Bennett DA; Buxbaum JD; Byrd GS; Carrasquillo MM; Crane PK
  • Comparison of detergent-insoluble proteome changes in autosomal dominant Alzheimer's disease brain to late onset AD and transgenic rodents
    Volume: 88
    04/18/2017 Authors: Hales C; Dammer E; Duong D; Gearing M; Cohen R; Wingo T; Lah J; Levey A; Seyfried N
  • A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease.
    Cell Syst Volume: 4 Page(s): 60 - 72.e4
    01/25/2017 Authors: Seyfried NT; Dammer EB; Swarup V; Nandakumar D; Duong DM; Yin L; Deng Q; Nguyen T; Hales CM; Wingo T
  • Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression.
    Proteomics Volume: 16 Page(s): 3042 - 3053
    12/01/2016 Authors: Hales CM; Dammer EB; Deng Q; Duong DM; Gearing M; Troncoso JC; Thambisetty M; Lah JJ; Shulman JM; Levey AI
  • Fewer Neurofibrillary Tangles and Slower Conversion to AD in MCI Patients Taking RAS Acting Antihypertensives
    Volume: 80 Page(s): S158 - S159
    10/01/2016 Authors: Wharton W; Zhao L; Steenland K; Gearing M; Goldstein F
  • Is C9orf72 ALS Different from Sporadic Disease? A Comparative Study in an ALS Clinic Population
    Volume: 80 Page(s): S170 - S170
    10/01/2016 Authors: Umoh M; Fournier C; Li Y; Polak M; Shaw L; Hu W; Gearing M; Glass J
  • Comparative analysis of C9orf72 and sporadic disease in an ALS clinic population.
    Neurology Volume: 87 Page(s): 1024 - 1030
    09/06/2016 Authors: Umoh ME; Fournier C; Li Y; Polak M; Shaw L; Landers JE; Hu W; Gearing M; Glass JD
  • 5-Hydroxymethylation-associated epigenetic modifiers of Alzheimer's disease modulate Tau-induced neurotoxicity.
    Hum Mol Genet Volume: 25 Page(s): 2437 - 2450
    06/15/2016 Authors: Bernstein AI; Lin Y; Street RC; Lin L; Dai Q; Yu L; Bao H; Gearing M; Lah JJ; Nelson PT
  • Applicability of digital analysis and imaging technology in neuropathology assessment.
    Neuropathology Volume: 36 Page(s): 270 - 282
    06/01/2016 Authors: Dunn WD; Gearing M; Park Y; Zhang L; Hanfelt J; Glass JD; Gutman DA
  • A Case of Adult-Onset Leukoencephalopathy with Spheroids and Pigmented Glia
    Volume: 75 Page(s): 603 - 603
    06/01/2016 Authors: Vega JV; Neill S; Schniederjan M; Hunter S; Glass J; Gearing M
  • Assessment of the genetic variance of late-onset Alzheimer's disease.
    Neurobiol Aging Volume: 41 Page(s): 200.e13 - 200.e20
    05/01/2016 Authors: Ridge PG; Hoyt KB; Boehme K; Mukherjee S; Crane PK; Haines JL; Mayeux R; Farrer LA; Pericak-Vance MA; Schellenberg GD
  • CSF complement 3 and factor H are staging biomarkers in Alzheimer's disease.
    Acta Neuropathol Commun Volume: 4 Page(s): 14
    02/17/2016 Authors: Hu WT; Watts KD; Tailor P; Nguyen TP; Howell JC; Lee RC; Seyfried NT; Gearing M; Hales CM; Levey AI
  • Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration.
    J Neurosci Volume: 36 Page(s): 1316 - 1323
    01/27/2016 Authors: Gentry EG; Henderson BW; Arrant AE; Gearing M; Feng Y; Riddle NC; Herskowitz JH
  • Presence of inclusions positive for polyglycine containing protein, FMRpolyG, indicates that repeat-associated non-AUG translation plays a role in fragile X-associated primary ovarian insufficiency.
    Hum Reprod Volume: 31 Page(s): 158 - 168
    01/01/2016 Authors: Buijsen RAM; Visser JA; Kramer P; Severijnen EAWFM; Gearing M; Charlet-Berguerand N; Sherman SL; Berman RF; Willemsen R; Hukema RK
  • Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.
    PLoS One Volume: 11 Page(s): e0148717
    01/01/2016 Authors: Karch CM; Ezerskiy LA; Bertelsen S; Alzheimers Disease Genetics Consortium (ADGC); Goate AM
  • Brain pathologies in extreme old age.
    Neurobiol Aging Volume: 37 Page(s): 1 - 11
    01/01/2016 Authors: Neltner JH; Abner EL; Jicha GA; Schmitt FA; Patel E; Poon LW; Marla G; Green RC; Davey A; Johnson MA
  • A novel Alzheimer disease locus located near the gene encoding tau protein.
    Mol Psychiatry Volume: 21 Page(s): 108 - 117
    01/01/2016 Authors: Jun G; Ibrahim-Verbaas CA; Vronskaya M; Lambert J-C; Chung J; Naj AC; Kunkle BW; Wang L-S; Bis JC; Bellenguez C
  • Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses.
    Alzheimers Dement Volume: 11 Page(s): 1439 - 1451
    12/01/2015 Authors: Mukherjee S; Walter S; Kauwe JSK; Saykin AJ; Bennett DA; Larson EB; Crane PK; Glymour MM; Adult Changes in Thought Study Investigators; Religious Orders Study/Memory and Aging Project Investigators
  • Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.
    Nat Commun Volume: 6 Page(s): 7247
    06/16/2015 Authors: Kouri N; Ross OA; Dombroski B; Younkin CS; Serie DJ; Soto-Ortolaza A; Baker M; Finch NCA; Yoon H; Kim J
  • Amyloid -abrogated TrkA ubiquitination in PC12 cells analogous to Alzheimer's disease.
    J Neurochem Volume: 133 Page(s): 919 - 925
    06/01/2015 Authors: Zheng C; Geetha T; Gearing M; Babu JR
  • Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.
    PLoS Med Volume: 12 Page(s): e1001841
    06/01/2015 Authors: stergaard SD; Mukherjee S; Sharp SJ; Proitsi P; Lotta LA; Day F; Perry JRB; Boehme KL; Walter S; Kauwe JS
  • Head injury does not alter disease progression or neuropathologic outcomes in ALS.
    Neurology Volume: 84 Page(s): 1788 - 1795
    04/28/2015 Authors: Fournier CN; Gearing M; Upadhyayula SR; Klein M; Glass JD
  • Tau phosphosignatures discriminate Alzheimer Disease from other tauopathies
    FASEB JOURNAL Volume: 29
    04/01/2015 Authors: Seyfried N; Dammer E; Ren R; Gearing M; Duc D; Lah J; Levey A
  • Rarity of the Alzheimer disease-protective APP A673T variant in the United States.
    JAMA Neurol Volume: 72 Page(s): 209 - 216
    02/01/2015 Authors: Wang L-S; Naj AC; Graham RR; Crane PK; Kunkle BW; Cruchaga C; Murcia JDG; Cannon-Albright L; Baldwin CT; Zetterberg H
  • Personality Structure Among Centenarians: The Georgia Centenarian Study.
    Exp Aging Res Volume: 41 Page(s): 361 - 385
    01/01/2015 Authors: Davey A; Siegler IC; Martin P; Costa PT; Poon LW; Georgia Centenarian Study
  • Potassium channel Kv1.3 is highly expressed by microglia in human Alzheimer's disease.
    J Alzheimers Dis Volume: 44 Page(s): 797 - 808
    01/01/2015 Authors: Rangaraju S; Gearing M; Jin L-W; Levey A
  • Quantitative phosphoproteomics of Alzheimer's disease reveals cross-talk between kinases and small heat shock proteins.
    Proteomics Volume: 15 Page(s): 508 - 519
    01/01/2015 Authors: Dammer EB; Lee AK; Duong DM; Gearing M; Lah JJ; Levey AI; Seyfried NT
  • Octogenarian and centenarian performance on the Fuld Object Memory Evaluation.
    Neuropsychol Dev Cogn B Aging Neuropsychol Cogn Volume: 22 Page(s): 438 - 451
    01/01/2015 Authors: Rahman-Filipiak A; Woodard JL; Miller LS; Martin P; Davey A; Poon LW; Georgia Centenarian Study
  • Aggregation properties of the small nuclear ribonucleoprotein U1-70K in Alzheimer disease.
    J Biol Chem Volume: 289 Page(s): 35296 - 35313
    12/19/2014 Authors: Diner I; Hales CM; Bishof I; Rabenold L; Duong DM; Yi H; Laur O; Gearing M; Troncoso J; Thambisetty M
  • Late-stage CTE pathology in a retired soccer player with dementia.
    Neurology Volume: 83 Page(s): 2307 - 2309
    12/09/2014 Authors: Hales C; Neill S; Gearing M; Cooper D; Glass J; Lah J
  • Primary age-related tauopathy (PART): a common pathology associated with human aging.
    Acta Neuropathol Volume: 128 Page(s): 755 - 766
    12/01/2014 Authors: Crary JF; Trojanowski JQ; Schneider JA; Abisambra JF; Abner EL; Alafuzoff I; Arnold SE; Attems J; Beach TG; Bigio EH
  • Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
    JAMA Neurol Volume: 71 Page(s): 1394 - 1404
    11/01/2014 Authors: Naj AC; Jun G; Reitz C; Kunkle BW; Perry W; Park YS; Beecham GW; Rajbhandary RA; Hamilton-Nelson KL; Wang L-S
  • Analysis of graft survival in a trial of stem cell transplant in ALS.
    Ann Clin Transl Neurol Volume: 1 Page(s): 900 - 908
    11/01/2014 Authors: Tadesse T; Gearing M; Senitzer D; Saxe D; Brat DJ; Bray R; Gebel H; Hill C; Boulis N; Riley J
  • Aggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease.
    Brain Pathol Volume: 24 Page(s): 344 - 351
    07/01/2014 Authors: Hales CM; Dammer EB; Diner I; Yi H; Seyfried NT; Gearing M; Glass JD; Montine TJ; Levey AI; Lah JJ
  • Loss of dopamine phenotype among midbrain neurons in Lesch-Nyhan disease.
    Ann Neurol Volume: 76 Page(s): 95 - 107
    07/01/2014 Authors: Gttle M; Prudente CN; Fu R; Sutcliffe D; Pang H; Cooper D; Veledar E; Glass JD; Gearing M; Visser JE
  • Hirano bodies differentially modulate cell death induced by tau and the amyloid precursor protein intracellular domain.
    BMC Neurosci Volume: 15 Page(s): 74
    06/14/2014 Authors: Spears W; Furgerson M; Sweetnam JM; Evans P; Gearing M; Fechheimer M; Furukawa R
  • Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer's [corrected] disease model.
    Nat Commun Volume: 5 Page(s): 4159
    06/13/2014 Authors: Wu Z; Guo Z; Gearing M; Chen G
  • FUS is phosphorylated by DNA-PK and accumulates in the cytoplasm after DNA damage.
    J Neurosci Volume: 34 Page(s): 7802 - 7813
    06/04/2014 Authors: Deng Q; Holler CJ; Taylor G; Hudson KF; Watkins W; Gearing M; Ito D; Murray ME; Dickson DW; Seyfried NT
  • 3R Predominant Tauopathy with Globular Glial Inclusions
    Volume: 73 Page(s): 624 - 624
    06/01/2014 Authors: Neill S; Glass J; Levey A; Parker M; Cooper D; Gearing M
  • U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21.
    Mol Neurodegener Volume: 9 Page(s): 15
    04/28/2014 Authors: Hales CM; Seyfried NT; Dammer EB; Duong D; Yi H; Gearing M; Troncoso JC; Mufson EJ; Thambisetty M; Levey AI
  • Elevated serum pesticide levels and risk for Alzheimer disease.
    JAMA Neurol Volume: 71 Page(s): 284 - 290
    03/01/2014 Authors: Richardson JR; Roy A; Shalat SL; von Stein RT; Hossain MM; Buckley B; Gearing M; Levey AI; German DC
  • TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions.
    Acta Neuropathol Volume: 127 Page(s): 407 - 418
    03/01/2014 Authors: Gallagher MD; Suh E; Grossman M; Elman L; McCluskey L; Van Swieten JC; Al-Sarraj S; Neumann M; Gelpi E; Ghetti B
  • ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
    Acta Neuropathol Volume: 127 Page(s): 825 - 843
    01/01/2014 Authors: Nelson PT; Estus S; Abner EL; Parikh I; Malik M; Neltner JH; Ighodaro E; Wang W-X; Wilfred BR; Wang L-S
  • Corrigendum: Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer's disease model.
    Nat Commun Volume: 5 Page(s): 4810
    01/01/2014 Authors: Wu Z; Guo Z; Gearing M; Chen G
  • Abnormal gephyrin immunoreactivity associated with Alzheimer disease pathologic changes.
    J Neuropathol Exp Neurol Volume: 72 Page(s): 1009 - 1015
    11/01/2013 Authors: Hales CM; Rees H; Seyfried NT; Dammer EB; Duong DM; Gearing M; Montine TJ; Troncoso JC; Thambisetty M; Levey AI
  • U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.
    Proc Natl Acad Sci U S A Volume: 110 Page(s): 16562 - 16567
    10/08/2013 Authors: Bai B; Hales CM; Chen P-C; Gozal Y; Dammer EB; Fritz JJ; Wang X; Xia Q; Duong DM; Street C
  • Neuron enriched nuclear proteome isolated from human brain.
    J Proteome Res Volume: 12 Page(s): 3193 - 3206
    07/05/2013 Authors: Dammer EB; Duong DM; Diner I; Gearing M; Feng Y; Lah JJ; Levey AI; Seyfried NT
  • NF-B activity is inversely correlated to RNF11 expression in Parkinson's disease.
    Neurosci Lett Volume: 547 Page(s): 16 - 20
    06/28/2013 Authors: Pranski E; Van Sanford CD; Dalal N; Orr AL; Karmali D; Cooper DS; Gearing M; Lah JJ; Levey AI; Betarbet R
  • RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-B signaling in dopaminergic cells.
    Neurobiol Dis Volume: 54 Page(s): 264 - 279
    06/01/2013 Authors: Pranski EL; Dalal NV; Sanford CV; Herskowitz JH; Gearing M; Lazo C; Miller GW; Lah JJ; Levey AI; Betarbet RS
  • Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration.
    Proc Natl Acad Sci U S A Volume: 110 Page(s): 7778 - 7783
    05/07/2013 Authors: Xu Z; Poidevin M; Li X; Li Y; Shu L; Nelson DL; Li H; Hales CM; Gearing M; Wingo TS
  • The Relationship of Lutein and DHA in Cognitive Function
    Volume: 27
    04/01/2013 Authors: Mohn E; Vishwanathan R; Lichtenstein AH; Matthan N; Hausman DB; Woodard JL; Davey A; Johnson MA; Poon LW; Green RC
  • Correlates of functional capacity among centenarians.
    J Appl Gerontol Volume: 32 Page(s): 324 - 346
    04/01/2013 Authors: Martin P; MacDonald M; Margrett J; Siegler I; Poon LW; Jazwinski SM; Green RC; Gearing M; Markesbery WR; Woodard JL
  • TDP-43 Inclusions in the Spinal Cord: Sensitivity and Specificity for the Diagnosis of Sporadic ALS
    Volume: 80
    02/12/2013 Authors: Upadhyayula S; Gearing M; Glass J
  • Relationship between Serum and Brain Carotenoids, -Tocopherol, and Retinol Concentrations and Cognitive Performance in the Oldest Old from the Georgia Centenarian Study.
    J Aging Res Volume: 2013 Page(s): 951786
    01/01/2013 Authors: Johnson EJ; Vishwanathan R; Johnson MA; Hausman DB; Davey A; Scott TM; Green RC; Miller LS; Gearing M; Woodard J
  • Age group differences in positive and negative affect among oldest-old adults: findings from the Georgia Centenarian Study.
    Int J Aging Hum Dev Volume: 77 Page(s): 261 - 288
    01/01/2013 Authors: Cho J; Martin P; Poon LW; Georgia Centenarian Study; MacDonald M; Jazwinski SM; Green RC; Gearing M; Johnson MA; Markesbery WR
  • Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
    Nat Genet Volume: 44 Page(s): 1349 - 1354
    12/01/2012 Authors: Whitcomb DC; LaRusch J; Krasinskas AM; Klei L; Smith JP; Brand RE; Neoptolemos JP; Lerch MM; Tector M; Sandhu BS
  • Amphiphysin-1 protein level changes associated with tau-mediated neurodegeneration.
    Neuroreport Volume: 23 Page(s): 942 - 946
    11/14/2012 Authors: De Jess-Corts HJ; Nogueras-Ortiz CJ; Gearing M; Arnold SE; Vega IE
  • Association between polychlorinated biphenyls and Parkinson's disease neuropathology.
    Neurotoxicology Volume: 33 Page(s): 1298 - 1304
    10/01/2012 Authors: Hatcher-Martin JM; Gearing M; Steenland K; Levey AI; Miller GW; Pennell KD
  • Asparaginyl endopeptidase cleaves TDP-43 in brain.
    Proteomics Volume: 12 Page(s): 2455 - 2463
    08/01/2012 Authors: Herskowitz JH; Gozal YM; Duong DM; Dammer EB; Gearing M; Ye K; Lah JJ; Peng J; Levey AI; Seyfried NT
  • Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases.
    Hum Mol Genet Volume: 21 Page(s): 3500 - 3512
    08/01/2012 Authors: Coppola G; Chinnathambi S; Lee JJ; Dombroski BA; Baker MC; Soto-Ortolaza AI; Lee SE; Klein E; Huang AY; Sears R
  • Novel late-onset Alzheimer disease loci variants associate with brain gene expression.
    Neurology Volume: 79 Page(s): 221 - 228
    07/17/2012 Authors: Allen M; Zou F; Chai HS; Younkin CS; Crook J; Pankratz VS; Carrasquillo MM; Rowley CN; Nair AA; Middha S
  • Comparative distribution of protein components of the A20 ubiquitin-editing complex in normal human brain.
    Neurosci Lett Volume: 520 Page(s): 104 - 109
    06/27/2012 Authors: Pranski EL; Van Sanford CD; Dalal NV; Orr AL; Karmali D; Cooper DS; Costa N; Heilman CJ; Gearing M; Lah JJ
  • Neuronal TDP-43-Positive Inclusions in the Spinal Cord Distinguish ALS from FTLD-TDP
    Volume: 71 Page(s): 590 - 590
    06/01/2012 Authors: Gearing M; Cooper D; Glass J
  • Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards.
    J Proteome Res Volume: 11 Page(s): 2721 - 2738
    05/04/2012 Authors: Seyfried NT; Gozal YM; Donovan LE; Herskowitz JH; Dammer EB; Xia Q; Ku L; Chang J; Duong DM; Rees HD
  • Localization of a toxic form of superoxide dismutase 1 protein to pathologically affected tissues in familial ALS.
    Proc Natl Acad Sci U S A Volume: 109 Page(s): 5505 - 5510
    04/03/2012 Authors: Brotherton TE; Li Y; Cooper D; Gearing M; Julien J-P; Rothstein JD; Boylan K; Glass JD
  • Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease.
    Proteomics Clin Appl Volume: 6 Page(s): 201 - 211
    04/01/2012 Authors: Donovan LE; Higginbotham L; Dammer EB; Gearing M; Rees HD; Xia Q; Duong DM; Seyfried NT; Lah JJ; Levey AI
  • Understanding dementia prevalence among centenarians.
    J Gerontol A Biol Sci Med Sci Volume: 67 Page(s): 358 - 365
    04/01/2012 Authors: Poon LW; Woodard JL; Stephen Miller L; Green R; Gearing M; Davey A; Arnold J; Martin P; Siegler IC; Nahapetyan L
  • Multidimensional predictors of fatigue among octogenarians and centenarians.
    Gerontology Volume: 58 Page(s): 249 - 257
    01/01/2012 Authors: Cho J; Martin P; Margrett J; MacDonald M; Johnson MA; Poon LW; Georgia Centenarian Study; Jazwinski SM; Green RC; Gearing M
  • Successful Recruitment of Centenarians for Post-Mortem Brain Donation: Results from the Georgia Centenarian Study.
    J Biosci Med Volume: 2
    01/01/2012 Authors: Shaw K; Gearing M; Davey A; Burgess M; Poon LW; Martin P; Green RC
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    J Psychol Volume: 146 Page(s): 173 - 188
    01/01/2012 Authors: Hensley B; Martin P; Margrett JA; MacDonald M; Siegler IC; Poon LW; Jazwinski SM; Green RC; Gearing M; Woodard JL
  • Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration.
    Mol Neurodegener Volume: 6 Page(s): 82
    11/29/2011 Authors: Gozal YM; Seyfried NT; Gearing M; Glass JD; Heilman CJ; Wuu J; Duong DM; Cheng D; Xia Q; Rees HD
  • FUS immunogold labeling TEM analysis of the neuronal cytoplasmic inclusions of neuronal intermediate filament inclusion disease: a frontotemporal lobar degeneration with FUS proteinopathy.
    J Mol Neurosci Volume: 45 Page(s): 409 - 421
    11/01/2011 Authors: Page T; Gitcho MA; Mosaheb S; Carter D; Chakraverty S; Perry RH; Bigio EH; Gearing M; Ferrer I; Goate AM
  • Spatial patterns of FUS-immunoreactive neuronal cytoplasmic inclusions (NCI) in neuronal intermediate filament inclusion disease (NIFID).
    J Neural Transm (Vienna) Volume: 118 Page(s): 1651 - 1657
    11/01/2011 Authors: Armstrong RA; Gearing M; Bigio EH; Cruz-Sanchez FF; Duyckaerts C; Mackenzie IRA; Perry RH; Skullerud K; Yokoo H; Cairns NJ
  • Ovarian histopathological and ubiquitin-immunophenotypic features in fragile X-associated primary ovarian insufficiency: a study of five cases and selected controls.
    Histopathology Volume: 59 Page(s): 1018 - 1023
    11/01/2011 Authors: Chang MC; DeCaro JJ; Zheng M; Gearing M; Shubeck L; Sherman SL; Welt CK
  • 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
    Nat Neurosci Volume: 14 Page(s): 1607 - 1616
    10/30/2011 Authors: Szulwach KE; Li X; Li Y; Song C-X; Wu H; Dai Q; Irier H; Upadhyay AK; Gearing M; Levey AI
  • -Hexachlorocyclohexane levels in serum and risk of Parkinson's disease.
    Neurotoxicology Volume: 32 Page(s): 640 - 645
    10/01/2011 Authors: Richardson JR; Roy A; Shalat SL; Buckley B; Winnik B; Gearing M; Levey AI; Factor SA; O'Suilleabhain P; German DC
  • Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.
    Nat Genet Volume: 43 Page(s): 699 - 705
    06/19/2011 Authors: Hglinger GU; Melhem NM; Dickson DW; Sleiman PMA; Wang L-S; Klei L; Rademakers R; de Silva R; Litvan I; Riley DE
  • The Spectrum of Neuropathology in Patients Dying With Amyotrophic Lateral Sclerosis (ALS) - A Clinicopathologic Study
    Volume: 70 Page(s): 531 - 531
    06/01/2011 Authors: Gearing M; Cooper D; Costa N; Glass J
  • Hippocampal sclerosis in advanced age: clinical and pathological features.
    Brain Volume: 134 Page(s): 1506 - 1518
    05/01/2011 Authors: Nelson PT; Schmitt FA; Lin Y; Abner EL; Jicha GA; Patel E; Thomason PC; Neltner JH; Smith CD; Santacruz KS
  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
    Nat Genet Volume: 43 Page(s): 436 - 441
    05/01/2011 Authors: Naj AC; Jun G; Beecham GW; Wang L-S; Vardarajan BN; Buros J; Gallins PJ; Buxbaum JD; Jarvik GP; Crane PK
  • Brain levels of lutein (L) and zeaxanthin (Z) are related to cognitive function in centenarians
    Volume: 25
    04/01/2011 Authors: Johnson EJ; Vishwanathan R; Schalch W; Poon L; Wittwer J; Johnson MA; Hausman D; Davey A; Green R; Gearing M
  • Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration.
    Arch Neurol Volume: 68 Page(s): 488 - 497
    04/01/2011 Authors: Chen-Plotkin AS; Martinez-Lage M; Sleiman PMA; Hu W; Greene R; Wood EM; Bing S; Grossman M; Schellenberg GD; Hatanpaa KJ
  • Serum carotenoids as a biomarker for carotenoid concentrations in the brain
    Volume: 25
    04/01/2011 Authors: Johnson EJ; Vishwanathan R; Scott TM; Schalch W; Wittwer J; Hausman DB; Davey A; Johnson MA; Green RC; Gearing M
  • Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease.
    J Biol Chem Volume: 286 Page(s): 10457 - 10465
    03/25/2011 Authors: Dammer EB; Na CH; Xu P; Seyfried NT; Duong DM; Cheng D; Gearing M; Rees H; Lah JJ; Levey AI
  • Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production.
    J Biol Chem Volume: 286 Page(s): 6117 - 6127
    02/25/2011 Authors: Herskowitz JH; Seyfried NT; Gearing M; Kahn RA; Peng J; Levey AI; Lah JJ
  • The spectrum and severity of FUS-immunoreactive inclusions in the frontal and temporal lobes of ten cases of neuronal intermediate filament inclusion disease.
    Acta Neuropathol Volume: 121 Page(s): 219 - 228
    02/01/2011 Authors: Armstrong RA; Gearing M; Bigio EH; Cruz-Sanchez FF; Duyckaerts C; Mackenzie IRA; Perry RH; Skullerud K; Yokoo H; Cairns NJ
  • Proteomic analysis of hippocampal dentate granule cells in frontotemporal lobar degeneration: application of laser capture technology.
    Front Neurol Volume: 2 Page(s): 24
    01/01/2011 Authors: Gozal YM; Dammer EB; Duong DM; Cheng D; Gearing M; Rees HD; Peng J; Lah JJ; Levey AI
  • Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration.
    J Proteome Res Volume: 9 Page(s): 6368 - 6379
    12/03/2010 Authors: Herskowitz JH; Seyfried NT; Duong DM; Xia Q; Rees HD; Gearing M; Peng J; Lah JJ; Levey AI
  • BRAIN PATHOLOGY AND MENTAL STATUS: FINDINGS FROM THE GEORGIA CENTENARIAN STUDY
    GERONTOLOGIST Volume: 50 Page(s): 149 - 150
    10/01/2010 Authors: Cho J; Martin P; Gearing M; MacDonald M; Margrett J; Green R; Woodard JL; Poon L
  • Cognitive performance in centenarians and the oldest old: norms from the Georgia Centenarian Study.
    Neuropsychol Dev Cogn B Aging Neuropsychol Cogn Volume: 17 Page(s): 575 - 590
    09/01/2010 Authors: Miller LS; Mitchell MB; Woodard JL; Davey A; Martin P; Poon LW; Jazwinski SM; Green RC; Gearing M; Markesbery WR
  • Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
    Nat Genet Volume: 42 Page(s): 234 - 239
    03/01/2010 Authors: Van Deerlin VM; Sleiman PMA; Martinez-Lage M; Chen-Plotkin A; Wang L-S; Graff-Radford NR; Dickson DW; Rademakers R; Boeve BF; Grossman M
  • Neuropathological heterogeneity in frontotemporal lobar degeneration with TDP-43 proteinopathy: a quantitative study of 94 cases using principal components analysis.
    J Neural Transm (Vienna) Volume: 117 Page(s): 227 - 239
    02/01/2010 Authors: Armstrong RA; Ellis W; Hamilton RL; Mackenzie IRA; Hedreen J; Gearing M; Montine T; Vonsattel J-P; Head E; Lieberman AP
  • Deficient high-affinity binding of Pittsburgh compound B in a case of Alzheimer's disease.
    Acta Neuropathol Volume: 119 Page(s): 221 - 233
    02/01/2010 Authors: Rosen RF; Ciliax BJ; Wingo TS; Gearing M; Dooyema J; Lah JJ; Ghiso JA; LeVine H; Walker LC
  • Glycoproteomics in neurodegenerative diseases.
    Mass Spectrom Rev Volume: 29 Page(s): 79 - 125
    01/01/2010 Authors: Hwang H; Zhang J; Chung KA; Leverenz JB; Zabetian CP; Peskind ER; Jankovic J; Su Z; Hancock AM; Pan C
  • Family history and adaptation among centenarians and octogenarians.
    Gerontology Volume: 56 Page(s): 83 - 87
    01/01/2010 Authors: Hensley B; Martin P; MacDonald M; Poon L; Georgia Centenarian Study; Jazwinski SM; Green RC; Gearing M; Markesbery WR; Woodard JL
  • Predicting happiness among centenarians.
    Gerontology Volume: 56 Page(s): 88 - 92
    01/01/2010 Authors: Bishop AJ; Martin P; MacDonald M; Poon L; Georgia Centenarian Study; Jazwinski SM; Green RC; Gearing M; Markesbery WR; Woodard JL
  • Social resources and longevity: findings from the Georgia centenarian study.
    Gerontology Volume: 56 Page(s): 106 - 111
    01/01/2010 Authors: Randall GK; Martin P; McDonald M; Poon LW; Georgia Centenarian Study; Jazwinski SM; Green RC; Gearing M; Markesbery WR; Woodard JL
  • Distal and proximal resource influences on economic dependency among the oldest old.
    Gerontology Volume: 56 Page(s): 100 - 105
    01/01/2010 Authors: MacDonald M; Aneja A; Martin P; Margrett J; Poon LW; Georgia Centenarian Study; Jazwinski SM; Green RC; Gearing M; Markesbery WR
  • Depression among centenarians and the oldest old: contributions of cognition and personality.
    Gerontology Volume: 56 Page(s): 93 - 99
    01/01/2010 Authors: Margrett J; Martin P; Woodard JL; Miller LS; MacDonald M; Baenziger J; Siegler IC; Davey A; Poon L; Georgia Centenarian Study
  • Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimer's disease.
    J Proteome Res Volume: 8 Page(s): 5069 - 5079
    11/01/2009 Authors: Gozal YM; Duong DM; Gearing M; Cheng D; Hanfelt JJ; Funderburk C; Peng J; Lah JJ; Levey AI
  • A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease.
    Neurobiol Dis Volume: 34 Page(s): 417 - 431
    06/01/2009 Authors: Mastroberardino PG; Hoffman EK; Horowitz MP; Betarbet R; Taylor G; Cheng D; Na HM; Gutekunst C-A; Gearing M; Trojanowski JQ
  • Age-associated oxidative damage to the p62 promoter: implications for Alzheimer disease.
    Free Radic Biol Med Volume: 46 Page(s): 492 - 501
    02/15/2009 Authors: Du Y; Wooten MC; Gearing M; Wooten MW
  • Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy.
    Science Volume: 323 Page(s): 124 - 127
    01/02/2009 Authors: Yang Q; She H; Gearing M; Colla E; Lee M; Shacka JJ; Mao Z
  • Characterization of osteopontin expression and function after status epilepticus.
    Epilepsia Volume: 49 Page(s): 1675 - 1685
    10/01/2008 Authors: Borges K; Gearing M; Rittling S; Sorensen ES; Kotloski R; Denhardt DT; Dingledine R
  • Fas-associated factor 1 and Parkinson's disease.
    Neurobiol Dis Volume: 31 Page(s): 309 - 315
    09/01/2008 Authors: Betarbet R; Anderson LR; Gearing M; Hodges TR; Fritz JJ; Lah JJ; Levey AI
  • Tauopathy with paired helical filaments in an aged chimpanzee.
    J Comp Neurol Volume: 509 Page(s): 259 - 270
    07/20/2008 Authors: Rosen RF; Farberg AS; Gearing M; Dooyema J; Long PM; Anderson DC; Davis-Turak J; Coppola G; Geschwind DH; Par J-F
  • Phosphoproteomic analysis of human brain by calcium phosphate precipitation and mass spectrometry.
    J Proteome Res Volume: 7 Page(s): 2845 - 2851
    07/01/2008 Authors: Xia Q; Cheng D; Duong DM; Gearing M; Lah JJ; Levey AI; Peng J
  • Cdk5-mediated regulation of the PIKE-A-Akt pathway and glioblastoma cell invasion.
    Proc Natl Acad Sci U S A Volume: 105 Page(s): 7570 - 7575
    05/27/2008 Authors: Liu R; Tian B; Gearing M; Hunter S; Ye K; Mao Z
  • Proteomic identification of novel proteins associated with Lewy bodies.
    Front Biosci Volume: 13 Page(s): 3850 - 3856
    05/01/2008 Authors: Xia Q; Liao L; Cheng D; Duong DM; Gearing M; Lah JJ; Levey AI; Peng J
  • Identification of proteins in human substantia nigra.
    Proteomics Clin Appl Volume: 2 Page(s): 776 - 782
    05/01/2008 Authors: Kitsou E; Pan S; Zhang J; Shi M; Zabeti A; Dickson DW; Albin R; Gearing M; Kashima DT; Wang Y
  • Re-evaluation of archival "DLDH" cases for frontotemporal lobar degeneration with ubiquitin inclusions: antigen retrieval is essential
    Volume: 67 Page(s): 513 - 513
    05/01/2008 Authors: Gearing M; Cooper D; Glass J
  • RE-EVALUATION OF ARCHIVAL "DLDH" CASES FOR FRONTOTEMPORAL LOBAR DEGENERATION WITH UBIQUITIN INCLUSIONS: ANTIGEN RETRIEVAL IS ESSENTIAL
    FASEB JOURNAL Volume: 22
    04/01/2008 Authors: Gearing M; Cooper D; Glass J
  • Mortalin: a protein associated with progression of Parkinson disease?
    J Neuropathol Exp Neurol Volume: 67 Page(s): 117 - 124
    02/01/2008 Authors: Shi M; Jin J; Wang Y; Beyer RP; Kitsou E; Albin RL; Gearing M; Pan C; Zhang J
  • Neuronal LR11/sorLA expression is reduced in mild cognitive impairment.
    Ann Neurol Volume: 62 Page(s): 640 - 647
    12/01/2007 Authors: Sager KL; Wuu J; Leurgans SE; Rees HD; Gearing M; Mufson EJ; Levey AI; Lah JJ
  • PARK10 candidate RNF11 is expressed by vulnerable neurons and localizes to Lewy bodies in Parkinson disease brain.
    J Neuropathol Exp Neurol Volume: 66 Page(s): 955 - 964
    10/01/2007 Authors: Anderson LR; Betarbet R; Gearing M; Gulcher J; Hicks AA; Stefnsson K; Lah JJ; Levey AI
  • Proteomics identification of proteins in human cortex using multidimensional separations and MALDI tandem mass spectrometer.
    Mol Cell Proteomics Volume: 6 Page(s): 1818 - 1823
    10/01/2007 Authors: Pan S; Shi M; Jin J; Albin RL; Lieberman A; Gearing M; Lin B; Pan C; Yan X; Kashima DT
  • Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities.
    EMBO J Volume: 26 Page(s): 2755 - 2767
    06/06/2007 Authors: Hu X; Shi Q; Zhou X; He W; Yi H; Yin X; Gearing M; Levey A; Yan R
  • Clinical and neuropathologic findings in a case of posterior cortical atrophy (PCA)
    Volume: 66 Page(s): 422 - 422
    05/01/2007 Authors: Gearing M; Brat DJ; Hunter SB; Cooper DS; Tehrani M; Lah JJ
  • Clinical and neuropathologic findings in a case of posterior cortical atrophy (PCA)
    Volume: 21 Page(s): A22 - A22
    04/01/2007 Authors: Gearing M; Brat DJ; Hunter SB; Cooper DS; Tehrani M; Lah JJ
  • Methodological Considerations in Studying Centenarians: Lessons Learned From the Georgia Centenarian Studies.
    Annu Rev Gerontol Geriatr Volume: 27 Page(s): 231 - 264
    01/01/2007 Authors: Poon LW; Jazwinski M; Green RC; Woodard JL; Martin P; Rodgers WL; Johnson MA; Hausman D; Arnold J; Davey A
  • Elevated levels of dieldrin are associated with Parkinson's disease
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Volume: 232 Page(s): 647 - 647
    09/10/2006 Authors: Pennell KD; Hatcher JM; Caudle WM; Richardson JR; Gearing M; Levey AI; Jones DP; Miller GW
  • Alzheimer's disease in centenarians: Neuropathologic findings in the Georgia Centenarian Study
    Volume: 16 Page(s): S158 - S158
    09/01/2006 Authors: Gearing M; Green RC; Poon LW; Burgess M; Markesbery WR
  • LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease.
    J Neuropathol Exp Neurol Volume: 65 Page(s): 866 - 872
    09/01/2006 Authors: Dodson SE; Gearing M; Lippa CF; Montine TJ; Levey AI; Lah JJ
  • Pick disease with overlapping neuropathologic features of progressive supranuclear palsy and extensive glial pathology
    Volume: 16 Page(s): S50 - S50
    09/01/2006 Authors: Gearing M; Johnson TM; Murrell JR; Ghetti B
  • A mutation of beta -actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia.
    Am J Hum Genet Volume: 78 Page(s): 947 - 960
    06/01/2006 Authors: Procaccio V; Salazar G; Ono S; Styers ML; Gearing M; Davila A; Jimenez R; Juncos J; Gutekunst C-A; Meroni G
  • Mutation analysis of patients with neuronal intermediate filament inclusion disease (NIFID).
    Neurobiol Aging Volume: 27 Page(s): 778.e1 - 778.e6
    05/01/2006 Authors: Momeni P; Cairns NJ; Perry RH; Bigio EH; Gearing M; Singleton AB; Hardy J
  • Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases.
    J Biol Chem Volume: 281 Page(s): 10816 - 10824
    04/21/2006 Authors: Choi J; Sullards MC; Olzmann JA; Rees HD; Weintraub ST; Bostwick DE; Gearing M; Levey AI; Chin L-S; Li L
  • The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments.
    J Neurosci Volume: 26 Page(s): 1596 - 1603
    02/01/2006 Authors: Offe K; Dodson SE; Shoemaker JT; Fritz JJ; Gearing M; Levey AI; Lah JJ
  • Proteins associated with Lewy body progression in human - a multiplex quantitative proteomic analysis
    Volume: 21 Page(s): S576 - S576
    01/01/2006 Authors: Jin J; Gearing M; Hulette C; Wang Y; Pan C; Li J; Zhang J
  • Neuronal intranuclear inclusions are ultrastructurally and immunologically distinct from cytoplasmic inclusions of neuronal intermediate filament inclusion disease.
    Acta Neuropathol Volume: 110 Page(s): 360 - 368
    10/01/2005 Authors: Mosaheb S; Thorpe JR; Hashemzadeh-Bonehi L; Bigio EH; Gearing M; Cairns NJ
  • Concomitant Alzheimer's disease and frontotemporal dementia-motor neuron disease subtype: A common neuropathologic phenomenon.
    Volume: 64 Page(s): 433 - 433
    05/01/2005 Authors: Gearing M; Lah JJ; Levey AI
  • Severe frontotemporal glial pathology and mild hippocampal degeneration associated with the P301L MAPT mutation: Study of a previously unreported family.
    Volume: 64 Page(s): 434 - 434
    05/01/2005 Authors: Spina S; Murrell JR; Gearing M; Levey A; Mirra S; Yamaguchi K; Ghetti B; Lah J
  • Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease.
    Neurology Volume: 63 Page(s): 1376 - 1384
    10/26/2004 Authors: Cairns NJ; Grossman M; Arnold SE; Burn DJ; Jaros E; Perry RH; Duyckaerts C; Stankoff B; Pillon B; Skullerud K
  • alpha-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases.
    Acta Neuropathol Volume: 108 Page(s): 213 - 223
    09/01/2004 Authors: Cairns NJ; Uryu K; Bigio EH; Mackenzie IRA; Gearing M; Duyckaerts C; Yokoo H; Nakazato Y; Jaros E; Perry RH
  • Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection.
    J Biol Chem Volume: 279 Page(s): 37061 - 37068
    08/27/2004 Authors: Liao L; Cheng D; Wang J; Duong DM; Losik TG; Gearing M; Rees HD; Lah JJ; Levey AI; Peng J
  • Loss of apolipoprotein E receptor LR11 in Alzheimer disease.
    Arch Neurol Volume: 61 Page(s): 1200 - 1205
    08/01/2004 Authors: Scherzer CR; Offe K; Gearing M; Rees HD; Fang G; Heilman CJ; Schaller C; Bujo H; Levey AI; Lah JJ
  • AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells.
    J Biol Chem Volume: 279 Page(s): 25430 - 25439
    06/11/2004 Authors: Salazar G; Love R; Styers ML; Werner E; Peden A; Rodriguez S; Gearing M; Wainer BH; Faundez V
  • alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease.
    Am J Pathol Volume: 164 Page(s): 2153 - 2161
    06/01/2004 Authors: Cairns NJ; Zhukareva V; Uryu K; Zhang B; Bigio E; Mackenzie IRA; Gearing M; Duyckaerts C; Yokoo H; Nakazato Y
  • Reduced expression of the multifunctional apolipoprotein E receptor LR11 plays an important role in Alzheimer's disease pathogenesis.
    Volume: 63 Page(s): 553 - 553
    05/01/2004 Authors: Gearing M; Lah JJ; Sager KL; Offer K; Dodson SE; Carter SC; Bennett DA; Mufson EJ; Levey AI
  • Alpha-synuclein deposits in the substantia nigra of individuals with Gerstmann-Straussler-Scheinker disease (F198S-129V).
    Volume: 63 Page(s): 527 - 527
    05/01/2004 Authors: Yamaguchi K; Piccardo P; Tagliavini F; Bugiani O; Giaccone G; Epperson F; Miravalle L; Farlow MR; Murrell JR; Gearing M
  • Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases.
    J Biol Chem Volume: 279 Page(s): 13256 - 13264
    03/26/2004 Authors: Choi J; Levey AI; Weintraub ST; Rees HD; Gearing M; Chin L-S; Li L
  • Plasma testosterone levels in Alzheimer and Parkinson diseases.
    Neurology Volume: 62 Page(s): 411 - 413
    02/10/2004 Authors: Okun MS; DeLong MR; Hanfelt J; Gearing M; Levey A
  • Actin brain aggregation in identical twins with dystonia and deafness: dysregulation of actin dynamics as a consequence of a bioenergetic defect
    Volume: 1657 Page(s): 44 - 45
    01/01/2004 Authors: Procaccio V; Gearing M; Ono S; Juncos J; Wallace D; Wainer B
  • Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model.
    Exp Neurol Volume: 182 Page(s): 21 - 34
    07/01/2003 Authors: Borges K; Gearing M; McDermott DL; Smith AB; Almonte AG; Wainer BH; Dingledine R
  • Very late onset Friedreich's ataxia with a 25-year clinical course and hemizygous trinucleotide expansion.
    Volume: 62 Page(s): 557 - 557
    05/01/2003 Authors: Castellano-Sanchez AA; Hunter SB; Gearing M; Brat DJ; Wilmot G; Koeppen AH
  • Unusual neuropathologic findings in a case of primary lateral sclerosis.
    Volume: 62 Page(s): 555 - 555
    05/01/2003 Authors: Gearing M; Castellano AA; Hunter SB; Brat DJ; Glass JD; Santoianni R; Juncos JL
  • Aggregation of actin and cofilin in identical twins with juvenile-onset dystonia.
    Ann Neurol Volume: 52 Page(s): 465 - 476
    10/01/2002 Authors: Gearing M; Juncos JL; Procaccio V; Gutekunst C-A; Marino-Rodriguez EM; Gyure KA; Ono S; Santoianni R; Krawiecki NS; Wallace DC
  • Actin aggregation in identical twins with dystonia: Consequence of a defect in bioenergetics.
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 61 Page(s): 460 - 460
    05/01/2002 Authors: Gearing M; Procaccio V; Ono S; Juncos JL; Wainer BH
  • Alpha-synuclein in the amygdala in Alzheimer's disease and dementia with Lewy bodies an immunohistochemical study.
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 61 Page(s): 456 - 456
    05/01/2002 Authors: Kindelberger D; Sheffield L; Gearing M; Mirra S
  • Refractory nonmotor symptoms in male Parkinson patients due to testosterone deficiency: A common unrecognized comorbidity
    Volume: 58 Page(s): A284 - A284
    04/09/2002 Authors: Okun MS; McDonald WM; Hanfelt J; Green J; Levey A; Ciliax B; Gearing M; Vitek JL; DeLong MR
  • Complications of gamma knife surgery for Parkinson disease.
    Arch Neurol Volume: 58 Page(s): 1995 - 2002
    12/01/2001 Authors: Okun MS; Stover NP; Subramanian T; Gearing M; Wainer BH; Holder CA; Watts RL; Juncos JL; Freeman A; Evatt ML
  • Apolipoprotein E and age at onset of Alzheimer's disease in African American patients.
    Neurology Volume: 57 Page(s): 1923 - 1925
    11/27/2001 Authors: Goldstein FC; Ashley AV; Gearing M; Hanfelt J; Penix L; Freedman LJ; Levey AI
  • Tau-associated neuropathology in ganglion cell tumours increases with patient age but appears unrelated to ApoE genotype.
    Neuropathol Appl Neurobiol Volume: 27 Page(s): 197 - 205
    06/01/2001 Authors: Brat DJ; Gearing M; Goldthwaite PT; Wainer BH; Burger PC
  • Multiple system atrophy (MSA) and Parkinson's disease (PD) pathology with diffuse cortical Lewy bodies in a patient evidencing multiple clinical phenotypes.
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 60 Page(s): 548 - 548
    05/01/2001 Authors: Gearing M; Juncos JL; Farrer M; Lincoln S; Wainer BH
  • Apolipoprotein E and age of onset of Alzheimer's disease in African American patients
    Volume: 56 Page(s): A113 - A114
    04/24/2001 Authors: Goldstein FC; Ashley AV; Gearing M; Hanfelt J; Penix L; Freedman L; Levey AI
  • Quetiapine treatment of psychotic symptoms in lewy body dementia: Long-term experience in 10 patients with three pathologically confirmed cases
    ANNALS OF NEUROLOGY Volume: 48 Page(s): 418 - 418
    09/01/2000 Authors: Juncos JL; Jewart DR; Gearing M; Wainer B
  • The role of neuropeptide Y in the progesterone-induced luteinizing hormone-releasing hormone surge in vivo in ovariectomized female rhesus monkeys.
    Endocrinology Volume: 141 Page(s): 1772 - 1779
    05/01/2000 Authors: Mizuno M; Gearing M; Terasawa E
  • Age-associated neurodegeneration in ganglion cell tumors.
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 59 Page(s): 438 - 438
    05/01/2000 Authors: Brat DJ; Goldthwaite P; Gearing M; Wainer BH; Burger PC
  • Unusual neuropathology in an identical twin with juvenile-onset dystonia negative for the DYT1 GAG deletion.
    Volume: 59 Page(s): 465 - 465
    05/01/2000 Authors: Gearing M; Juncos JL; Gutekunst CA; Marino E; Wainer BH
  • The utility of apolipoprotein E genotyping in the diagnosis of Alzheimer disease in a community-based case series.
    Arch Neurol Volume: 56 Page(s): 1489 - 1495
    12/01/1999 Authors: Tsuang D; Larson EB; Bowen J; McCormick W; Teri L; Nochlin D; Leverenz JB; Peskind ER; Lim A; Raskind MA
  • Comparison of Lewy body variant of Alzheimer's disease with pure Alzheimer's disease: Consortium to Establish a Registry for Alzheimer's Disease, Part XIX.
    Neurology Volume: 52 Page(s): 1839 - 1844
    06/10/1999 Authors: Heyman A; Fillenbaum GG; Gearing M; Mirra SS; Welsh-Bohmer KA; Peterson B; Pieper C
  • Neuropathological changes and apolipoprotein E genotype in Alzheimer's disease (AD) with concomitant Lewy bodies: An alpha-synuclein immunohistochemical study.
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 58 Page(s): 553 - 553
    05/01/1999 Authors: Gearing M; Schultz A; Ghetti B; Mirra SS
  • Neuropathological changes and apolipoprotein E genotype in Alzheimer's disease (AD) with concomitant Lewy bodies: An alpha-synuclein immunohistochemical study.
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 58 Page(s): 552 - 552
    05/01/1999 Authors: Gearing M; Schultz A; Ghetti B; Piccardo P; Mirra SS
  • The utility of apolipoprotein E genotyping in the diagnosis of Alzheimer's disease in a community-based case series
    BIOLOGICAL PSYCHIATRY Volume: 45 Page(s): 138S - 138S
    04/15/1999 Authors: Tsuang D; Larson EB; Bowen J; McCormick M; Teri L; Nochlin D; Leverenz J; Peskind ER; Lim A; Raskind M
  • Tau pathology in a family with dementia and a P301L mutation in tau.
    J Neuropathol Exp Neurol Volume: 58 Page(s): 335 - 345
    04/01/1999 Authors: Mirra SS; Murrell JR; Gearing M; Spillantini MG; Goedert M; Crowther RA; Levey AI; Jones R; Green J; Shoffner JM
  • Neurofibrillary pathology in Alzheimer disease with Lewy bodies: two subgroups.
    Arch Neurol Volume: 56 Page(s): 203 - 208
    02/01/1999 Authors: Gearing M; Lynn M; Mirra SS
  • Progression of regional neuropathology in Alzheimer disease and normal elderly: findings from the Nun study.
    Alzheimer Dis Assoc Disord Volume: 13 Page(s): 226 - 231
    01/01/1999 Authors: Wolf DS; Gearing M; Snowdon DA; Mori H; Markesbery WR; Mirra SS
  • Cerebral infarcts in patients with autopsy-proven Alzheimer's disease: CERAD, part XVIII. Consortium to Establish a Registry for Alzheimer's Disease.
    Neurology Volume: 51 Page(s): 159 - 162
    07/01/1998 Authors: Heyman A; Fillenbaum GG; Welsh-Bohmer KA; Gearing M; Mirra SS; Mohs RC; Peterson BL; Pieper CF
  • Tau cytopathology in a patient with familial early onset dementia.
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 57 Page(s): 509 - 509
    05/01/1998 Authors: Gearing M; Levey AI; Jones R; Walton W; Shoffner JM; Schmidt ML; Trojanowski JO; Ghetti B; Mirra SS
  • Clinical and neuropsychological findings in patients with autopsy evidence of Alzheimer's disease with and without cerebral infarction: The CERAD experience
    NEUROLOGY Volume: 50 Page(s): A408 - A408
    04/01/1998 Authors: Heyman A; Fillenbaum G; Welsh-Bohmer K; Gearing M; Mirra SS; Mohs R; Peterson B; Pieper C
  • Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype.
    Arch Neurol Volume: 55 Page(s): 326 - 335
    03/01/1998 Authors: Berg L; McKeel DW; Miller JP; Storandt M; Rubin EH; Morris JC; Baty J; Coats M; Norton J; Goate AM
  • Diffuse plaques in the striatum in Alzheimer disease (AD): relationship to the striatal mosaic and selected neuropeptide markers.
    J Neuropathol Exp Neurol Volume: 56 Page(s): 1363 - 1370
    12/01/1997 Authors: Gearing M; Levey AI; Mirra SS
  • Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease.
    Ann Neurol Volume: 42 Page(s): 319 - 325
    09/01/1997 Authors: Welsh-Bohmer KA; Gearing M; Saunders AM; Roses AD; Mirra S
  • Coexistence of prion protein (PrP) amyloid, neurofibrillary tangles, and lewy bodies in Gerstmann-Straussler Scheinker disease with prion gene (PRNP) mutation F198S
    BRAIN PATHOLOGY Volume: 7 Page(s): 1379 - 1379
    09/01/1997 Authors: Mirra SS; Young K; Gearing M; Jones R; Evatt ML; Piccardo P; Ghetti B
  • Neurofibrillary pathology in Alzheimer's disease with concomitant Parkinson's disease changes: Two subgroups.
    BRAIN PATHOLOGY Volume: 7 Page(s): 1368 - 1368
    09/01/1997 Authors: Gearing M; Mirra SS
  • Neuropathologic assessment of Alzheimer's disease.
    Neurology Volume: 49 Page(s): S14 - S16
    09/01/1997 Authors: Mirra SS; Gearing M; Nash F
  • Brain infarction and the clinical expression of Alzheimer disease.
    JAMA Volume: 278 Page(s): 113 - 114
    07/09/1997 Authors: Roman GC
  • Brain infarction and the clinical expression of Alzheimer disease.
    JAMA Volume: 278 Page(s): 113
    07/09/1997 Authors: Mirra SS; Gearing M
  • Prion protein (PrP) amyloid coexists with neurofibrillary tangles and Lewy bodies in a patient from a new family of Gerstmann Straussler Scheinker disease (GSS).
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 56 Page(s): 102 - 102
    05/01/1997 Authors: Mirra SS; Gearing M; Jones R; Evatt ML; Young K; Piccardo P; Ghetti B
  • Alzheimer's disease with concomitant Parkinson's disease changes: Two subgroups defined by neurofibrillary pathology.
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 56 Page(s): 180 - 180
    05/01/1997 Authors: Gearing M; Mirra SS
  • Astrocyte-apolipoprotein E associations in senile plaques in Alzheimer disease and vascular lesions: a regional immunohistochemical study.
    J Neuropathol Exp Neurol Volume: 56 Page(s): 376 - 381
    04/01/1997 Authors: Shao Y; Gearing M; Mirra SS
  • Corticobasal degeneration: neuropathologic and clinical heterogeneity.
    Neurology Volume: 48 Page(s): 959 - 969
    04/01/1997 Authors: Schneider JA; Watts RL; Gearing M; Brewer RP; Mirra SS
  • Abeta1-40 but not Abeta1-42 levels in cortex correlate with apolipoprotein E epsilon4 allele dosage in sporadic Alzheimer's disease.
    Brain Res Volume: 748 Page(s): 250 - 252
    02/14/1997 Authors: Ishii K; Tamaoka A; Mizusawa H; Shoji S; Ohtake T; Fraser PE; Takahashi H; Tsuji S; Gearing M; Mizutani T
  • beta-Amyloid (A beta) deposition in the brains of aged orangutans.
    Neurobiol Aging Volume: 18 Page(s): 139 - 146
    01/01/1997 Authors: Gearing M; Tigges J; Mori H; Mirra SS
  • Progression of Alzheimer's disease (AD) pathology from biopsy to autopsy.
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 55 Page(s): 160 - 160
    05/01/1996 Authors: Gearing M; Schneider JA; Mori H; Mirra SS
  • AD neuropathology - Reply
    NEUROLOGY Volume: 46 Page(s): 1186 - 1187
    04/01/1996 Authors: Gearing M; Mirra SS; Hedreen JC; Sumi SM; Hansen LA; Heyman A
  • Abeta-peptide length and apolipoprotein E genotype in Alzheimer's disease.
    Ann Neurol Volume: 39 Page(s): 395 - 399
    03/01/1996 Authors: Gearing M; Mori H; Mirra SS
  • A beta40 is a major form of beta-amyloid in nonhuman primates.
    Neurobiol Aging Volume: 17 Page(s): 903 - 908
    01/01/1996 Authors: Gearing M; Tigges J; Mori H; Mirra SS
  • Alzheimer's disease with and without coexisting Parkinson's disease changes: apolipoprotein E genotype and neuropathologic correlates.
    Neurology Volume: 45 Page(s): 1985 - 1990
    11/01/1995 Authors: Gearing M; Schneider JA; Rebeck GW; Hyman BT; Mirra SS
  • Regional variation in the distribution of apolipoprotein E and A beta in Alzheimer's disease.
    J Neuropathol Exp Neurol Volume: 54 Page(s): 833 - 841
    11/01/1995 Authors: Gearing M; Schneider JA; Robbins RS; Hollister RD; Mori H; Games D; Hyman BT; Mirra SS
  • Ubiquitin-positive CA2/3 neurites in hippocampus coexist with cortical Lewy bodies.
    Neurology Volume: 45 Page(s): 1768 - 1770
    09/01/1995 Authors: Kim H; Gearing M; Mirra SS
  • Apolipoprotein E genotype in diverse neurodegenerative disorders.
    Ann Neurol Volume: 38 Page(s): 131 - 135
    07/01/1995 Authors: Schneider JA; Gearing M; Robbins RS; de l'Aune W; Mirra SS
  • STRIATAL PLAQUES OCCUR RELATIVELY EARLY IN THE PROGRESSION OF ALZHEIMERS-DISEASE CHANGES
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 54 Page(s): 427 - 427
    05/01/1995 Authors: GEARING M; SCHNEIDER JA; GREEN RC; MIRRA SS
  • CORTICOBASAL DEGENERATION - A NEUROPATHOLOGICAL, CLINICAL, AND MOLECULAR STUDY
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 54 Page(s): 446 - 446
    05/01/1995 Authors: SCHNEIDER JA; GEARING M; WATTS R; MIRRA SS
  • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part X. Neuropathology confirmation of the clinical diagnosis of Alzheimer's disease.
    Neurology Volume: 45 Page(s): 461 - 466
    03/01/1995 Authors: Gearing M; Mirra SS; Hedreen JC; Sumi SM; Hansen LA; Heyman A
  • CONSORTIUM TO ESTABLISH A REGISTRY FOR ALZHEIMERS-DISEASE - REPLY
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 54 Page(s): 131 - 131
    01/01/1995 Authors: MIRRA SS; GEARING M; MCKEEL DW; CRAIN BJ; HUGHES JP; VANBELLE G; HEYMAN A
  • The CERAD experience, Part VIII: Neuroimaging-neuropathology correlates of temporal lobe changes in Alzheimer's disease.
    Neurology Volume: 45 Page(s): 178 - 179
    01/01/1995 Authors: Davis PC; Gearing M; Gray L; Mirra SS; Morris JC; Edland SD; Lin T; Heyman A
  • Interlaboratory comparison of neuropathology assessment in Alzheimer's disease.
    J Neuropathol Exp Neurol Volume: 54 Page(s): 129 - 131
    01/01/1995 Authors: Jellinger KA; Bancher C; Fischer P
  • Neuropathology and apolipoprotein E profile of aged chimpanzees: implications for Alzheimer disease.
    Proc Natl Acad Sci U S A Volume: 91 Page(s): 9382 - 9386
    09/27/1994 Authors: Gearing M; Rebeck GW; Hyman BT; Tigges J; Mirra SS
  • Progressive supranuclear palsy: neuropathologic and clinical heterogeneity.
    Neurology Volume: 44 Page(s): 1015 - 1024
    06/01/1994 Authors: Gearing M; Olson DA; Watts RL; Mirra SS
  • Apolipoprotein E4 and beta amyloid in senile plaques and cerebral blood vessels of aged rhesus monkeys.
    Am J Pathol Volume: 144 Page(s): 1183 - 1187
    06/01/1994 Authors: Poduri A; Gearing M; Rebeck GW; Mirra SS; Tigges J; Hyman BT
  • Interlaboratory comparison of neuropathology assessments in Alzheimer's disease: a study of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD).
    J Neuropathol Exp Neurol Volume: 53 Page(s): 303 - 315
    05/01/1994 Authors: Mirra SS; Gearing M; McKeel DW; Crain BJ; Hughes JP; van Belle G; Heyman A
  • APOLIPOPROTEIN-E AND REGIONAL VARIATION IN DIFFUSE PLAQUES IN ALZHEIMERS-DISEASE (AD) WITH AND WITHOUT PARKINSONS-DISEASE (PD) CHANGES - AN IMMUNOHISTOCHEMICAL AND MOLECULAR STUDY
    NEUROBIOLOGY OF AGING Volume: 15 Page(s): S118 - S119
    01/01/1994 Authors: GEARING M; SCHNEIDER JA; ROBBINS RS; REBECK GW; HYMAN BT; MIRRA SS
  • UBIQUITIN IMMUNOREACTIVE CA2-3 NEURITES IN HIPPOCAMPUS COEXIST WITH CORTICAL LEWY BODIES
    NEUROBIOLOGY OF AGING Volume: 15 Page(s): S114 - S114
    01/01/1994 Authors: KIM H; GEARING M; MIRRA SS
  • Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients.
    Genomics Volume: 17 Page(s): 171 - 184
    07/01/1993 Authors: Shoffner JM; Brown MD; Torroni A; Lott MT; Cabell MF; Mirra SS; Beal MF; Yang CC; Gearing M; Salvo R
  • COMPARATIVE NEUROPATHOLOGICAL STUDY OF AGED PRIMATE BRAINS
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 52 Page(s): 306 - 306
    05/01/1993 Authors: MIRRA SS; GEARING M; TIGGES J
  • STRIATAL MATRIX AND AMYLOID DEPOSITION IN ALZHEIMERS-DISEASE AND RELATED DISORDERS
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 52 Page(s): 306 - 306
    05/01/1993 Authors: GEARING M; MIRRA SS
  • Amyloid precursor protein (APP) in the striatum in Alzheimer's disease: an immunohistochemical study.
    J Neuropathol Exp Neurol Volume: 52 Page(s): 22 - 30
    01/01/1993 Authors: Gearing M; Wilson RW; Unger ER; Shelton ER; Chan HW; Masters CL; Beyreuther K; Mirra SS
  • CLINICAL-PATHOLOGICAL HETEROGENEITY IN PROGRESSIVE SUPRANUCLEAR PALSY
    ANNALS OF NEUROLOGY Volume: 32 Page(s): 244 - 244
    08/01/1992 Authors: OLSON DA; GEARING M; WATTS RL; MIRRA SS
  • CONCOMITANT ALZHEIMERS-DISEASE (AD) AND PARKINSONS-DISEASE (PD) CHANGES IN PROGRESSIVE SUPRANUCLEAR PALSY (PSP)
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 51 Page(s): 324 - 324
    05/01/1992 Authors: GEARING M; OLSON DA; MIRRA SS
  • Prostaglandin E2 mediates the stimulatory effect of methoxamine on in vivo luteinizing hormone-releasing hormone (LH-RH) release in the ovariectomized female rhesus monkey.
    Brain Res Volume: 560 Page(s): 276 - 281
    09/27/1991 Authors: Gearing M; Terasawa E
  • CORRELATION OF DEMENTIA SEVERITY WITH PLAQUE AND TANGLE FREQUENCIES IN MIDFRONTAL CORTEX IN CERAD CASES WITH ALZHEIMERS-DISEASE
    ANNALS OF NEUROLOGY Volume: 30 Page(s): 249 - 249
    08/01/1991 Authors: MORRIS JC; MIRRA S; DAVIS P; GEARING M; MOHS R; HUGHES JP; HEYMAN A
  • AMYLOID PRECURSOR PROTEIN (APP) IN CORTEX AND STRIATUM IN ALZHEIMERS-DISEASE (AD) - AN IMMUNOHISTOCHEMICAL STUDY
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 50 Page(s): 314 - 314
    05/01/1991 Authors: GEARING M; WILSON RW; UNGER ER; SHELTON ER; CHAN HW; MIRRA SS
  • The alpha-1-adrenergic neuronal system is involved in the pulsatile release of luteinizing hormone-releasing hormone in the ovariectomized female rhesus monkey.
    Neuroendocrinology Volume: 53 Page(s): 373 - 381
    04/01/1991 Authors: Gearing M; Terasawa E
  • Suppression of luteinizing hormone release by the 1-adrenergic receptor antagonist prazosin in the ovariectomized female rhesus monkey.
    Am J Primatol Volume: 25 Page(s): 23 - 33
    01/01/1991 Authors: Gearing M; Terasawa E
  • Norepinephrine is a possible neurotransmitter stimulating pulsatile release of luteinizing hormone-releasing hormone in the rhesus monkey.
    Endocrinology Volume: 123 Page(s): 1808 - 1816
    10/01/1988 Authors: Terasawa E; Krook C; Hei DL; Gearing M; Schultz NJ; Davis GA
  • Luteinizing hormone releasing hormone (LHRH) neuroterminals mapped using the push-pull perfusion method in the rhesus monkey.
    Brain Res Bull Volume: 21 Page(s): 117 - 121
    07/01/1988 Authors: Gearing M; Terasawa E
  • Steroidogenesis by the immature rhesus monkey ovary in vitro.
    J Endocrinol Invest Volume: 9 Page(s): 171 - 175
    04/01/1986 Authors: Bruot BC; Gearing M; Musey PI; Wilson ME; Collins DC
  • EFFECT OF PROLACTIN ON LIPOPROTEIN UTILIZATION BY THE CORPUS-LUTEUM
    FEDERATION PROCEEDINGS Volume: 42 Page(s): 317 - 317
    01/01/1983 Authors: BRUOT BC; GEARING M; COLLINS DC
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