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Profile

Harish Joshi PhD

  • Department of Cell Biology
    Associate Professor, Emeritus
  • (404) 727-6273
  • harish.joshi@emory.edu

Academic Appointment

  • Assoc. Professor, Department of Cell Biology, Emory University School of Medicine

Education

Degrees

  • B. Sc. from BSNV College, University of Lucknow
  • PhD from University of Delhi
  • M. Sc. from University of Lucknow

Research

Publications

  • Author Correction: Synergistic suppression of noscapine and conventional chemotherapeutics on human glioblastoma cell growth.
    Acta Pharmacol Sin Volume: 43 Page(s): 1100
    04/01/2022 Authors: Qi Q; Liu X; Li S; Joshi HC; Ye K
  • Runt-related transcription factor 1 promotes apoptosis and inhibits neuroblastoma progression in vitro and in vivo.
    J Exp Clin Cancer Res Volume: 39 Page(s): 52
    03/20/2020 Authors: Hong M; He J; Li D; Chu Y; Pu J; Tong Q; Joshi HC; Tang S; Li S
  • Molecular modeling reveals binding interface of -tubulin with GCP4 and interactions with noscapinoids.
    Proteins Volume: 83 Page(s): 827 - 843
    05/01/2015 Authors: Suri C; Joshi HC; Naik PK
  • Molecular insight into - tubulin lateral interactions within the -tubulin ring complex (-TuRC).
    J Comput Aided Mol Des Volume: 28 Page(s): 961 - 972
    09/01/2014 Authors: Suri C; Hendrickson TW; Joshi HC; Naik PK
  • The microtubule binding drug EM011 inhibits the growth of paediatric low grade gliomas.
    Cancer Lett Volume: 335 Page(s): 109 - 118
    07/10/2013 Authors: Ajeawung NF; Joshi HC; Kamnasaran D
  • Synergistic suppression of noscapine and conventional chemotherapeutics on human glioblastoma cell growth.
    Acta Pharmacol Sin Volume: 34 Page(s): 930 - 938
    07/01/2013 Authors: Qi Q; Liu X; Li S; Joshi HC; Ye K
  • Investigation of Targetin, a Microtubule Binding Agent which Regresses the Growth of Pediatric High and Low Grade Gliomas.
    J Pediatr Oncol Volume: 1 Page(s): 32 - 40
    01/01/2013 Authors: Ajeawung NF; Joshi HC; Kamnasaran D
  • In-Vitro and Ex-Vivo Investigations of the Microtubule Binding Drug Targetin on Angiogenesis.
    J Pediatr Oncol Volume: 1 Page(s): 41 - 47
    01/01/2013 Authors: Ajeawung NF; Mononen L; Thorn A; Pin A-L; Joshi HC; Huot J; Kamnasaran D
  • Brominated Noscapine Inhibits the Growth of Pediatric Low Grade Astrocytomas
    Volume: 48 Page(s): 104 - 105
    11/01/2012 Authors: Ajeawung N; Joshi H; Kamnasaran D
  • Chemoprevention of familial adenomatous polyposis by bromo-noscapine (EM011) in the Apc(Min/+) mouse model.
    Int J Cancer Volume: 131 Page(s): 1435 - 1444
    09/15/2012 Authors: Li S; Ghaleb AM; He J; Bughani U; Bialkowska AB; Yang VW; Joshi HC
  • Copper(I) mediated facile synthesis of potent tubulin polymerization inhibitor, 9-amino--noscapine from natural -noscapine.
    Bioorg Med Chem Lett Volume: 22 Page(s): 2983 - 2987
    04/15/2012 Authors: Manchukonda NK; Sridhar B; Naik PK; Joshi HC; Kantevari S
  • In silico inspired design and synthesis of a novel tubulin-binding anti-cancer drug: folate conjugated noscapine (Targetin).
    J Comput Aided Mol Des Volume: 26 Page(s): 233 - 247
    02/01/2012 Authors: Naik PK; Lopus M; Aneja R; Vangapandu SN; Joshi HC
  • Noscapine induced apoptosis via downregulation of survivin in human neuroblastoma cells having wild type or null p53.
    PLoS One Volume: 7 Page(s): e40076
    01/01/2012 Authors: Li S; He J; Li S; Cao G; Tang S; Tong Q; Joshi HC
  • Noscapinoids with anti-cancer activity against human acute lymphoblastic leukemia cells (CEM): a three dimensional chemical space pharmacophore modeling and electronic feature analysis.
    J Mol Model Volume: 18 Page(s): 307 - 318
    01/01/2012 Authors: Naik PK; Santoshi S; Joshi HC
  • DISCOVERY OF A NEW CLASS OF MICROTUBULE-BINDING DRUGS THAT SIGNIFICANTLY AFFECT THE VIABILITY AND TRANSFORMATION OF HUMAN GLIOMA STEM CELLS
    NEURO-ONCOLOGY Volume: 13 Page(s): 107 - 107
    11/01/2011 Authors: Ajeawung N; Joshi H; Kamnasaran D
  • Rational design of novel anti-microtubule agent (9-azido-noscapine) from quantitative structure activity relationship (QSAR) evaluation of noscapinoids.
    J Biomol Screen Volume: 16 Page(s): 1047 - 1058
    10/01/2011 Authors: Santoshi S; Naik PK; Joshi HC
  • Discovery of a New Class of Microtubule Binding Drugs Which Significantly Affect the Viability and Transformation of Human Glioma Stem Cells
    Volume: 47 Page(s): S589 - S590
    09/01/2011 Authors: Ajeawung N; Joshi H; Kamnasaran D
  • Molecular modelling and competition binding study of Br-noscapine and colchicine provide insight into noscapinoid-tubulin binding site.
    J Mol Graph Model Volume: 29 Page(s): 947 - 955
    06/01/2011 Authors: Naik PK; Santoshi S; Rai A; Joshi HC
  • Rational design, synthesis and biological evaluations of amino-noscapine: a high affinity tubulin-binding noscapinoid.
    J Comput Aided Mol Des Volume: 25 Page(s): 443 - 454
    05/01/2011 Authors: Naik PK; Chatterji BP; Vangapandu SN; Aneja R; Chandra R; Kanteveri S; Joshi HC
  • A novel microtubule-modulating noscapinoid triggers apoptosis by inducing spindle multipolarity via centrosome amplification and declustering.
    Cell Death Differ Volume: 18 Page(s): 632 - 644
    04/01/2011 Authors: Karna P; Rida PCG; Pannu V; Gupta KK; Dalton WB; Joshi H; Yang VW; Zhou J; Aneja R
  • A novel microtubule-modulating agent induces mitochondrially driven caspase-dependent apoptosis via mitotic checkpoint activation in human prostate cancer cells.
    Eur J Cancer Volume: 46 Page(s): 1668 - 1678
    06/01/2010 Authors: Aneja R; Miyagi T; Karna P; Ezell T; Shukla D; Vij Gupta M; Yates C; Chinni SR; Zhau H; Chung LWK
  • Abundance of a distinct cluster of telomere t-stumps in advanced breast cancer cell line.
    Oncol Lett Volume: 1 Page(s): 339 - 343
    03/01/2010 Authors: Pai RB; Pai SB; Yang L; Joshi HC
  • Proteases and Kinases: Attractive Targets for Combating Infectious Diseases
    Volume: 1 Page(s): 49 - 69
    01/01/2010 Authors: Arabshahi M; Bughani U; Vangapandu SN; Aneja R; Chandra R; Kalman D; Joshi H
  • Non-toxic melanoma therapy by a novel tubulin-binding agent.
    Int J Cancer Volume: 126 Page(s): 256 - 265
    01/01/2010 Authors: Aneja R; Asress S; Dhiman N; Awasthi A; Rida PCG; Arora SK; Zhou J; Glass JD; Joshi HC
  • Recent patents reveal microtubules as persistent promising target for novel drug development for cancers.
    Recent Pat Antiinfect Drug Discov Volume: 4 Page(s): 164 - 182
    11/01/2009 Authors: Bughani U; Li S; Joshi HC
  • 9-bromonoscapine-induced mitotic arrest of cigarette smoke condensate-transformed breast epithelial cells.
    J Cell Biochem Volume: 106 Page(s): 1146 - 1156
    04/15/2009 Authors: Jaiswal AS; Aneja R; Connors SK; Joshi HC; Multani AS; Pathak S; Narayan S
  • Parkin regulates Eg5 expression by Hsp70 ubiquitination-dependent inactivation of c-Jun NH2-terminal kinase.
    J Biol Chem Volume: 283 Page(s): 35783 - 35788
    12/19/2008 Authors: Liu M; Aneja R; Sun X; Xie S; Wang H; Wu X; Dong J-T; Li M; Joshi HC; Zhou J
  • Modulation of multidrug resistance in cancer cells by the E3 ubiquitin ligase seven-in-absentia homologue 1.
    J Pathol Volume: 214 Page(s): 508 - 514
    03/01/2008 Authors: Liu M; Aneja R; Wang H; Sun L; Dong X; Huo L; Joshi H; Zhou J
  • Multidrug resistance-associated protein-overexpressing teniposide-resistant human lymphomas undergo apoptosis by a tubulin-binding agent.
    Cancer Res Volume: 68 Page(s): 1495 - 1503
    03/01/2008 Authors: Aneja R; Liu M; Yates C; Gao J; Dong X; Zhou B; Vangapandu SN; Zhou J; Joshi HC
  • EM044, a novel noscapinoid induces apoptosis in prostate cancer cells while sparing the normal stroma
    MOLECULAR CANCER THERAPEUTICS Volume: 6 Page(s): 3432S - 3432S
    12/01/2007 Authors: Aneja R; Yates C; Josson S; Chung LW; Joshi HC
  • Nonimmunosuppressive chemotherapy: EM011-treated mice mount normal T-cell responses to an acute lymphocytic choriomeningitis virus infection.
    Mol Cancer Ther Volume: 6 Page(s): 2891 - 2899
    11/01/2007 Authors: Aneja R; Kalia V; Ahmed R; Joshi HC
  • Preclinical pharmacokinetics and bioavailability of noscapine, a tubulin-binding anticancer agent.
    Cancer Chemother Pharmacol Volume: 60 Page(s): 831 - 839
    11/01/2007 Authors: Aneja R; Dhiman N; Idnani J; Awasthi A; Arora SK; Chandra R; Joshi HC
  • PO(2)-dependent differential regulation of multidrug resistance 1 gene expression by the c-Jun NH2-terminal kinase pathway.
    J Biol Chem Volume: 282 Page(s): 17581 - 17586
    06/15/2007 Authors: Liu M; Li D; Aneja R; Joshi HC; Xie S; Zhang C; Zhou J
  • p53 and p21 determine the sensitivity of noscapine-induced apoptosis in colon cancer cells.
    Cancer Res Volume: 67 Page(s): 3862 - 3870
    04/15/2007 Authors: Aneja R; Ghaleb AM; Zhou J; Yang VW; Joshi HC
  • Synthesis and biological evaluation of a cyclic ether fluorinated noscapine analog.
    Bioorg Med Chem Volume: 14 Page(s): 8352 - 8358
    12/15/2006 Authors: Aneja R; Vangapandu SN; Joshi HC
  • Treatment of hormone-refractory breast cancer: apoptosis and regression of human tumors implanted in mice.
    Mol Cancer Ther Volume: 5 Page(s): 2366 - 2377
    09/01/2006 Authors: Aneja R; Zhou J; Zhou B; Chandra R; Joshi HC
  • Synthesis of microtubule-interfering halogenated noscapine analogs that perturb mitosis in cancer cells followed by cell death.
    Biochem Pharmacol Volume: 72 Page(s): 415 - 426
    08/14/2006 Authors: Aneja R; Vangapandu SN; Lopus M; Viswesarappa VG; Dhiman N; Verma A; Chandra R; Panda D; Joshi HC
  • Inhibition of the mitotic kinesin Eg5 up-regulates Hsp70 through the phosphatidylinositol 3-kinase/Akt pathway in multiple myeloma cells.
    J Biol Chem Volume: 281 Page(s): 18090 - 18097
    06/30/2006 Authors: Liu M; Aneja R; Liu C; Sun L; Gao J; Wang H; Dong J-T; Sarli V; Giannis A; Joshi HC
  • Development of a novel nitro-derivative of noscapine for the potential treatment of drug-resistant ovarian cancer and T-cell lymphoma.
    Mol Pharmacol Volume: 69 Page(s): 1801 - 1809
    06/01/2006 Authors: Aneja R; Vangapandu SN; Lopus M; Chandra R; Panda D; Joshi HC
  • Recent patents on proteases and kinases as anti-infective agents: a review.
    Recent Pat Antiinfect Drug Discov Volume: 1 Page(s): 209 - 224
    06/01/2006 Authors: Vangapandu SN; Aneja R; Chandra R; Joshi HC
  • Rational design of the microtubule-targeting anti-breast cancer drug EM015.
    Cancer Res Volume: 66 Page(s): 3782 - 3791
    04/01/2006 Authors: Aneja R; Lopus M; Zhou J; Vangapandu SN; Ghaleb A; Yao J; Nettles JH; Zhou B; Gupta M; Panda D
  • Noscapine-induced apoptosis in human colon cancer cells is p53-dependent
    Volume: 66
    04/01/2006 Authors: Aneja R; Ghaleb A; Yang V; Joshi H
  • Drug-resistant T-lymphoid tumors undergo apoptosis selectively in response to an antimicrotubule agent, EM011.
    Blood Volume: 107 Page(s): 2486 - 2492
    03/15/2006 Authors: Aneja R; Zhou J; Vangapandu SN; Zhou B; Chandra R; Joshi HC
  • Reversal of P-glycoprotein-mediated multidrug resistance in cancer cells by the c-Jun NH2-terminal kinase.
    Cancer Res Volume: 66 Page(s): 445 - 452
    01/01/2006 Authors: Zhou J; Liu M; Aneja R; Chandra R; Lage H; Joshi HC
  • Noscapine inhibits tumor progression by selectively inducing apoptosis in vitro and in vivo without compromising immune surveillance: Implications for combining chemotherapy and immunotherapy.
    Volume: 11 Page(s): 9088S - 9089S
    12/15/2005 Authors: Aneja R; Kaalia V; Ahmed R; Joshi HC
  • Rational design of noscapine family members as microtubule-targeting anticancer drugs.
    Volume: 11 Page(s): 9089S - 9089S
    12/15/2005 Authors: Aneja R; Lopus M; Nettles JH; Panda D; Joshi HC
  • EM012, a microtubule-interfering agent, inhibits the progression of multidrug-resistant human ovarian cancer both in cultured cells and in athymic nude mice.
    Cancer Chemother Pharmacol Volume: 55 Page(s): 461 - 465
    05/01/2005 Authors: Zhou J; Liu M; Luthra R; Jones J; Aneja R; Chandra R; Tekmal RR; Joshi HC
  • Enhancement of paclitaxel-induced microtubule stabilization, mitotic arrest, and apoptosis by the microtubule-targeting agent EM012.
    Biochem Pharmacol Volume: 68 Page(s): 2435 - 2441
    12/15/2004 Authors: Zhou J; Liu M; Aneja R; Chandra R; Joshi HC
  • Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth.
    Clin Cancer Res Volume: 10 Page(s): 5187 - 5201
    08/01/2004 Authors: Landen JW; Hau V; Wang M; Davis T; Ciliax B; Wainer BH; Van Meir EG; Glass JD; Joshi HC; Archer DR
  • Human ninein is a centrosomal autoantigen recognized by CREST patient sera and plays a regulatory role in microtubule nucleation.
    Cell Cycle Volume: 3 Page(s): 923 - 930
    07/01/2004 Authors: Stillwell EE; Zhou J; Joshi HC
  • Short duration of elevated vIRF-1 expression during lytic replication of human herpesvirus 8 limits its ability to block antiviral responses induced by alpha interferon in BCBL-1 cells.
    J Virol Volume: 78 Page(s): 6621 - 6635
    06/01/2004 Authors: Pozharskaya VP; Weakland LL; Zimring JC; Krug LT; Unger ER; Neisch A; Joshi H; Inoue N; Offermann MK
  • Microtubule-interacting drugs for cancer treatment.
    Trends Pharmacol Sci Volume: 24 Page(s): 361 - 365
    07/01/2003 Authors: Checchi PM; Nettles JH; Zhou J; Snyder JP; Joshi HC
  • Brominated derivatives of noscapine are potent microtubule-interfering agents that perturb mitosis and inhibit cell proliferation.
    Mol Pharmacol Volume: 63 Page(s): 799 - 807
    04/01/2003 Authors: Zhou J; Gupta K; Aggarwal S; Aneja R; Chandra R; Panda D; Joshi HC
  • Gamma-tubulin is involved in the coordination of chromosome segregation and cytokinesis
    Volume: 13 Page(s): 197A - 197A
    11/01/2002 Authors: Yao J; Leung SW; Uzawa S; Toda T; Joshi HC
  • Noscapine derivatives as potent microtubule-interfering agents that perturb mitosis and induce apoptosis
    Volume: 13 Page(s): 464A - 464A
    11/01/2002 Authors: Zhou J; Gupta K; Aggarwal S; Aneja R; Chandra R; Panda D; Joshi HC
  • Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine.
    J Biol Chem Volume: 277 Page(s): 39777 - 39785
    10/18/2002 Authors: Zhou J; Gupta K; Yao J; Ye K; Panda D; Giannakakou P; Joshi HC
  • Attachment and tension in the spindle assembly checkpoint.
    J Cell Sci Volume: 115 Page(s): 3547 - 3555
    09/15/2002 Authors: Zhou J; Yao J; Joshi HC
  • Noscapine alters microtubule dynamics in living cells and inhibits the progression of melanoma.
    Cancer Res Volume: 62 Page(s): 4109 - 4114
    07/15/2002 Authors: Landen JW; Lang R; McMahon SJ; Rusan NM; Yvon A-M; Adams AW; Sorcinelli MD; Campbell R; Bonaccorsi P; Ansel JC
  • Minor alteration of microtubule dynamics causes loss of tension across kinetochore pairs and activates the spindle checkpoint.
    J Biol Chem Volume: 277 Page(s): 17200 - 17208
    05/10/2002 Authors: Zhou J; Panda D; Landen JW; Wilson L; Joshi HC
  • Regulation of tubulin synthesis and cell cycle progression in mammalian cells by gamma-tubulin-mediated microtubule nucleation.
    J Cell Biochem Volume: 84 Page(s): 472 - 483
    01/01/2002 Authors: Zhou J; Shu H-B; Joshi HC
  • Mass spectral studies on aryl-substituted N-carbamoyl/N-thiocarbamoyl narcotine and related compounds.
    Rapid Commun Mass Spectrom Volume: 16 Page(s): 923 - 928
    01/01/2002 Authors: Aggarwal S; Ghosh NN; Aneja R; Joshi H; Chandra R
  • Sustained activation of p34(cdc2) is required for noscapine-induced apoptosis.
    J Biol Chem Volume: 276 Page(s): 46697 - 46700
    12/14/2001 Authors: Ye K; Zhou J; Landen JW; Bradbury EM; Joshi HC
  • Gamma-tubulin plays a role in the spindle assembly checkpoint and mitotic exit
    MOLECULAR BIOLOGY OF THE CELL Volume: 12 Page(s): 410A - 410A
    11/01/2001 Authors: Yao J; Uzawa S; Leung S; Hendrickson TW; Joshi HC
  • Exquisite modulation of microtubule dynamics is required for chromosome congression during mitosis
    MOLECULAR BIOLOGY OF THE CELL Volume: 12 Page(s): 173A - 173A
    11/01/2001 Authors: Zhou J; Joshi HC
  • Conditional mutations in gamma-tubulin reveal its involvement in chromosome segregation and cytokinesis.
    Mol Biol Cell Volume: 12 Page(s): 2469 - 2481
    08/01/2001 Authors: Hendrickson TW; Yao J; Bhadury S; Corbett AH; Joshi HC
  • The alkaloid noscapine is a low toxicity agent with significant antitumor effects in melanoma
    JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 117 Page(s): 484 - 484
    08/01/2001 Authors: Lang R; Landen J; McMahon S; Adams A; Campbell R; Bonaccorsi P; Archer D; Ansel J; Joshi H; Armstrong C
  • Kendrin/pericentrin-B, a centrosome protein with homology to pericentrin that complexes with PCM-1.
    J Cell Sci Volume: 114 Page(s): 797 - 809
    02/01/2001 Authors: Li Q; Hansen D; Killilea A; Joshi HC; Palazzo RE; Balczon R
  • Gamma tubulin and microtubule nucleation in mammalian cells.
    Methods Cell Biol Volume: 67 Page(s): 179 - 193
    01/01/2001 Authors: Joshi HC; Zhou J
  • Mutations in gamma-tubulin reveal its genetic interactions with proteins involved in sister chromatid separation.
    MOLECULAR BIOLOGY OF THE CELL Volume: 11 Page(s): 202A - 202A
    12/01/2000 Authors: Hendrickson TW; Yao J; Joshi HC
  • Sustained activation of p34cdc2 is required for noscapine-induced apoptosis
    MOLECULAR BIOLOGY OF THE CELL Volume: 11 Page(s): 253A - 253A
    12/01/2000 Authors: Ye KQ; Zhou J; Landen JW; Bradbury EM; Joshi HC
  • A new role of gamma-tubulin in the metaphase-anaphase transition is separable from the spindle assembly function
    MOLECULAR BIOLOGY OF THE CELL Volume: 11 Page(s): 7A - 7A
    12/01/2000 Authors: Leung SW; Uzawa S; Yao J; Hendrickson T; Watanabe Y; Joshi HC
  • Noscapine and analogues as potential chemotherapeutic agents.
    Drug News Perspect Volume: 13 Page(s): 543 - 546
    11/01/2000 Authors: Joshi HC; Zhou J
  • Noscapine inhibits tumor growth with little toxicity to normal tissues or inhibition of immune responses.
    Cancer Immunol Immunother Volume: 49 Page(s): 217 - 225
    07/01/2000 Authors: Ke Y; Ye K; Grossniklaus HE; Archer DR; Joshi HC; Kapp JA
  • Multiple isoforms of human ninein: the centrosomal localization domains and the microtubule nucleation
    MOLECULAR BIOLOGY OF THE CELL Volume: 10 Page(s): 17A - 17A
    11/01/1999 Authors: Stillwell EE; Joshi H; Medsgar T
  • A novel suppressor gene of mutant human gamma-tubulin gene in fission yeast
    MOLECULAR BIOLOGY OF THE CELL Volume: 10 Page(s): 130A - 130A
    11/01/1999 Authors: Leung SW; Uzawa S; Yao J; Joshi HC
  • Generation of conditional mutant alleles of gamma-tubulin by alanine scanning mutagenesis
    MOLECULAR BIOLOGY OF THE CELL Volume: 10 Page(s): 141A - 141A
    11/01/1999 Authors: Hendrickson TW; Bhadury S; Shanks JR; Joshi HC
  • Centrosome reduction during mouse spermiogenesis.
    Dev Biol Volume: 203 Page(s): 424 - 434
    11/15/1998 Authors: Manandhar G; Sutovsky P; Joshi HC; Stearns T; Schatten G
  • Characterization of alanine scanning mutants of human gamma-tubulin.
    MOLECULAR BIOLOGY OF THE CELL Volume: 9 Page(s): 408A - 408A
    11/01/1998 Authors: Hendrickson TW; Bhadury S; Shanks JR; Chung D; Crawford K; Joshi HC
  • Beta-adrenergic and fibroblast growth factor receptors induce neuronal process outgrowth through different mechanisms.
    Eur J Neurosci Volume: 10 Page(s): 2776 - 2789
    09/01/1998 Authors: Kwon JH; Vogt Weisenhorn DM; Downen M; Ruan K; Roback L; Joshi H; Wainer BH
  • Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells.
    Proc Natl Acad Sci U S A Volume: 95 Page(s): 1601 - 1606
    02/17/1998 Authors: Ye K; Ke Y; Keshava N; Shanks J; Kapp JA; Tekmal RR; Petros J; Joshi HC
  • Microtubule dynamics in living cells.
    Curr Opin Cell Biol Volume: 10 Page(s): 35 - 44
    02/01/1998 Authors: Joshi HC
  • Discovery of a cell cycle-dependent novel mitotic protein.
    MOLECULAR BIOLOGY OF THE CELL Volume: 8 Page(s): 327 - 327
    11/01/1997 Authors: Stillwell E; Palacios M; Fertig N; Medsgar T; Joshi H
  • Activation of SAPK/JNK1 links noscapine arrested mitosis and apoptosis
    MOLECULAR BIOLOGY OF THE CELL Volume: 8 Page(s): 862 - 862
    11/01/1997 Authors: Yel K; Liu X; Branum GD; Bradbury EM; Joshi HC
  • Opium alkaloid noscapine is an anti-tumor agent that promotes microtubule assembly induces apoptosis in dividing cells
    MOLECULAR BIOLOGY OF THE CELL Volume: 8 Page(s): 2223 - 2223
    11/01/1997 Authors: Ye K; Ke Y; Kapp JA; Nagalaksami N; Tekmal RR; Kean TE; Petros J; Joshi HC
  • A novel fission yeast gene, sog1+, is required for proper chromosome segregation.
    MOLECULAR BIOLOGY OF THE CELL Volume: 8 Page(s): 2252 - 2252
    11/01/1997 Authors: Leung SW; Uzawa S; Yao J; Joshi HC
  • Centrosome reduction during mouse spermiogenesis-centriole and gamma-tubulin degeneration.
    MOLECULAR BIOLOGY OF THE CELL Volume: 8 Page(s): 323 - 323
    11/01/1997 Authors: Manandhar G; Joshi HC; Stearns T; Schatten G
  • Altered binding of alanine-scanning gamma-tubulin mutants to taxol-stabilized microtubules.
    MOLECULAR BIOLOGY OF THE CELL Volume: 8 Page(s): 254 - 254
    11/01/1997 Authors: Hendrickson TW; Bhadury S; Shanks JR; Joshi HC
  • Microtubule organization and distribution of gamma-tubulin in male meiosis of lepidoptera.
    Mol Reprod Dev Volume: 45 Page(s): 547 - 559
    12/01/1996 Authors: Wolf KW; Joshi HC
  • Study of a novel fission yeast gene, Sog1+, involve in chromosome segregation.
    MOLECULAR BIOLOGY OF THE CELL Volume: 7 Page(s): 1222 - 1222
    12/01/1996 Authors: Leung SW; Uzawa S; Joshi HC
  • Microtubule organization and distribution of gamma-tubulin in male meiosis of lepidoptera
    MOLECULAR REPRODUCTION AND DEVELOPMENT Volume: 45 Page(s): 547 - 559
    12/01/1996 Authors: Wolf KW; Joshi HC
  • Distribution of gamma-tubulin differs in primary and secondary oocytes of Ephestia kuehniella (Pyralidae, Lepidoptera).
    Mol Reprod Dev Volume: 45 Page(s): 225 - 230
    10/01/1996 Authors: Wolf KW; Joshi HC
  • Tubulin transport in neurons.
    J Cell Biol Volume: 133 Page(s): 1355 - 1366
    06/01/1996 Authors: Miller KE; Joshi HC
  • gamma-Tubulin and microtubule organization in plants.
    Trends Cell Biol Volume: 6 Page(s): 41 - 44
    02/01/1996 Authors: Joshi HC; Palevitz BA
  • Microtubule organization and the distribution of gamma-tubulin in spermatogenesis of a beetle, Tenebrio molitor (Tenebrionidae, Coleoptera, Insecta).
    J Cell Sci Volume: 108 ( Pt 12) Page(s): 3855 - 3865
    12/01/1995 Authors: Wolf KW; Joshi HC
  • MICROTUBULES DO NOT MOVE BY SLOW AXONAL-TRANSPORT, BUT TUBULIN DOES
    MOLECULAR BIOLOGY OF THE CELL Volume: 6 Page(s): 1510 - 1510
    11/01/1995 Authors: MILLER KE; JOSHI HC
  • A NOVEL CELL-CYCLE DEPENDENT 350KD NUCLEAR-PROTEIN IN MAMMALIAN-CELLS
    MOLECULAR BIOLOGY OF THE CELL Volume: 6 Page(s): 429 - 429
    11/01/1995 Authors: LI Q; KE Y; KAPP JA; FERTIG N; MEDSGER TA; JOSHI HC
  • PHENOTYPIC ANALYSIS OF SOG1 MUTANT OF FISSION YEAST
    MOLECULAR BIOLOGY OF THE CELL Volume: 6 Page(s): 2106 - 2106
    11/01/1995 Authors: UZAWA S; LEUNG SW; JOSHI HC
  • FUNCTIONS AND STRUCTURAL-PROPERTIES OF GAMMA-TUBULIN IN MAMMALIAN-CELLS
    MOLECULAR BIOLOGY OF THE CELL Volume: 6 Page(s): 2136 - 2136
    11/01/1995 Authors: JOSHI HC; SHU HB
  • A role for microfilaments but not microtubules in processing soluble antigens.
    Cell Immunol Volume: 166 Page(s): 25 - 34
    11/01/1995 Authors: Soreng KM; Weber DA; Joshi H; Moore JC; Jensen PE
  • CLONING OF A CELL CYCLE-DEPENDENT MITOTIC PROTEIN USING HUMAN AUTOIMMUNE SERUM
    MOLECULAR BIOLOGY OF THE CELL Volume: 6 Page(s): 236 - 236
    11/01/1995 Authors: STILLWELL E; PALACIOS M; SHU HB; FERTIG N; MEDSGAR T; JOSHI H
  • gamma-tubulin is a minus end-specific microtubule binding protein.
    J Cell Biol Volume: 131 Page(s): 207 - 214
    10/01/1995 Authors: Li Q; Joshi HC
  • A transient association of gamma-tubulin at the midbody is required for the completion of cytokinesis during the mammalian cell division.
    J Cell Sci Volume: 108 ( Pt 9) Page(s): 2955 - 2962
    09/01/1995 Authors: Shu HB; Li Z; Palacios MJ; Li Q; Joshi HC
  • Gamma-tubulin can both nucleate microtubule assembly and self-assemble into novel tubular structures in mammalian cells.
    J Cell Biol Volume: 130 Page(s): 1137 - 1147
    09/01/1995 Authors: Shu HB; Joshi HC
  • Effects of Cisplatin and mafosfamide on the interphase microtubular cytoskeleton of a human breast-cancer cell-line, mx-1, in-vitro - a fine-structure and antitubulin immunofluorescence study.
    Int J Oncol Volume: 7 Page(s): 593 - 602
    09/01/1995 Authors: Wolf K; Mendoza A; Mentzel M; Wossmann W; Joshi H
  • A novel cell-cycle-dependent 350-kDa nuclear protein: C-terminal domain sufficient for nuclear localization.
    Biochem Biophys Res Commun Volume: 212 Page(s): 220 - 228
    07/06/1995 Authors: Li Q; Ke Y; Kapp JA; Fertig N; Medsger TA; Joshi HC
  • Experimental manipulation of gamma-tubulin distribution in Arabidopsis using anti-microtubule drugs.
    Cell Motil Cytoskeleton Volume: 31 Page(s): 113 - 129
    01/01/1995 Authors: Liu B; Joshi HC; Palevitz BA
  • Microtubule organizing centers and gamma-tubulin.
    Curr Opin Cell Biol Volume: 6 Page(s): 54 - 62
    02/01/1994 Authors: Joshi HC
  • gamma-Tubulin in Arabidopsis: gene sequence, immunoblot, and immunofluorescence studies.
    Plant Cell Volume: 6 Page(s): 303 - 314
    02/01/1994 Authors: Liu B; Joshi HC; Wilson TJ; Silflow CD; Palevitz BA; Snustad DP
  • Inhibition of microtubule nucleation at the neuronal centrosome compromises axon growth.
    Neuron Volume: 12 Page(s): 271 - 280
    02/01/1994 Authors: Ahmad FJ; Joshi HC; Centonze VE; Baas PW
  • Gamma-tubulin: the hub of cellular microtubule assemblies.
    Bioessays Volume: 15 Page(s): 637 - 643
    10/01/1993 Authors: Joshi HC
  • A new perspective on microtubules and axon growth.
    J Cell Biol Volume: 121 Page(s): 1191 - 1196
    06/01/1993 Authors: Joshi HC; Baas PW
  • Apical orientation of the microtubule organizing center and associated gamma-tubulin during the polarization of the retinal pigment epithelium in vivo.
    Dev Biol Volume: 157 Page(s): 147 - 156
    05/01/1993 Authors: Rizzolo LJ; Joshi HC
  • Gamma-tubulin in differentiated cell types: localization in the vicinity of basal bodies in retinal photoreceptors and ciliated epithelia.
    J Cell Sci Volume: 104 ( Pt 4) Page(s): 1229 - 1237
    04/01/1993 Authors: Muresan V; Joshi HC; Besharse JC
  • A gamma-tubulin-related protein associated with the microtubule arrays of higher plants in a cell cycle-dependent manner.
    J Cell Sci Volume: 104 ( Pt 4) Page(s): 1217 - 1228
    04/01/1993 Authors: Liu B; Marc J; Joshi HC; Palevitz BA
  • Gamma-tubulin reorganization during mouse fertilization and early development.
    J Cell Sci Volume: 104 ( Pt 2) Page(s): 383 - 389
    02/01/1993 Authors: Palacios MJ; Joshi HC; Simerly C; Schatten G
  • Immunogold electron microscopy: mapping tubulin isotypes on neurite microtubules.
    Methods Cell Biol Volume: 37 Page(s): 259 - 281
    01/01/1993 Authors: Joshi HC
  • Gamma-tubulin is associated with a cortical-microtubule-organizing zone in the developing guard cells of Allium cepa L.
    Planta Volume: 191 Page(s): 357 - 361
    01/01/1993 Authors: McDonald AR; Liu B; Joshi HC; Palevitz BA
  • Gamma-tubulin distribution in the neuron: implications for the origins of neuritic microtubules.
    J Cell Biol Volume: 119 Page(s): 171 - 178
    10/01/1992 Authors: Baas PW; Joshi HC
  • IMMUNOFLUORESCENCE LOCALIZATION OF GAMMA-TUBULIN IN PLANT-CELLS
    MOLECULAR BIOLOGY OF THE CELL Volume: 3 Page(s): A344 - A344
    09/01/1992 Authors: LIU B; MARC J; JOSHI HC; PALEVITZ BA
  • GAMMA-TUBULIN REORGANIZATION DURING MOUSE FERTILIZATION AND EARLY DEVELOPMENT
    MOLECULAR BIOLOGY OF THE CELL Volume: 3 Page(s): A97 - A97
    09/01/1992 Authors: PALACIOS M; JOSHI HC; SIMERLY C; SCHATTEN G
  • GAMMA-TUBULIN DISTRIBUTION IN THE RETINAL-PIGMENT EPITHELIUM - IMPLICATIONS FOR THE ESTABLISHMENT OF POLARITY
    MOLECULAR BIOLOGY OF THE CELL Volume: 3 Page(s): A276 - A276
    09/01/1992 Authors: RIZZOLO LJ; JOSHI HC
  • GAMMA-TUBULIN DISTRIBUTION IN THE NEURON - IMPLICATIONS FOR THE ORIGINS OF NEURITIC MICROTUBULES
    MOLECULAR BIOLOGY OF THE CELL Volume: 3 Page(s): A262 - A262
    09/01/1992 Authors: BAAS PW; JOSHI HC
  • A-GAMMA-TUBULIN HOMOLOG IN PLANT-CELLS
    MOLECULAR BIOLOGY OF THE CELL Volume: 3 Page(s): A47 - A47
    09/01/1992 Authors: MARC J; LIU B; JOSHI HC; PALEVITZ BA
  • Gamma-tubulin is a centrosomal protein required for cell cycle-dependent microtubule nucleation.
    Nature Volume: 356 Page(s): 80 - 83
    03/05/1992 Authors: Joshi HC; Palacios MJ; McNamara L; Cleveland DW
  • Tubulin site interpretation.
    Nature Volume: 344 Page(s): 389
    03/29/1990 Authors: Cleveland DW; Joshi HC; Murphy DB
  • Diversity among tubulin subunits: toward what functional end?
    Cell Motil Cytoskeleton Volume: 16 Page(s): 159 - 163
    01/01/1990 Authors: Joshi HC; Cleveland DW
  • Differential utilization of beta-tubulin isotypes in differentiating neurites.
    J Cell Biol Volume: 109 Page(s): 663 - 673
    08/01/1989 Authors: Joshi HC; Cleveland DW
  • Tension and compression in the cytoskeleton of PC-12 neurites. II: Quantitative measurements.
    J Cell Biol Volume: 107 Page(s): 665 - 674
    08/01/1988 Authors: Dennerll TJ; Joshi HC; Steel VL; Buxbaum RE; Heidemann SR
  • In vivo coassembly of a divergent beta-tubulin subunit (c beta 6) into microtubules of different function.
    J Cell Biol Volume: 105 Page(s): 2179 - 2190
    11/01/1987 Authors: Joshi HC; Yen TJ; Cleveland DW
  • The cytoskeleton of neurites after microtubule depolymerization.
    Exp Cell Res Volume: 163 Page(s): 233 - 245
    03/01/1986 Authors: Joshi HC; Baas P; Chu DT; Heidemann SR
  • Tension and compression in the cytoskeleton of PC 12 neurites.
    J Cell Biol Volume: 101 Page(s): 697 - 705
    09/01/1985 Authors: Joshi HC; Chu D; Buxbaum RE; Heidemann SR
  • Synergistic effects of cyclic AMP and nerve growth factor on neurite outgrowth and microtubule stability of PC12 cells.
    J Cell Biol Volume: 100 Page(s): 916 - 927
    03/01/1985 Authors: Heidemann SR; Joshi HC; Schechter A; Fletcher JR; Bothwell M
  • PC-12 NEURITES REGENERATED IN NGF ALONE OR NGF AND CAMP DIFFER IN STABILITY TO MICROTUBULE DEPOLYMERIZATION
    JOURNAL OF CELL BIOLOGY Volume: 99 Page(s): A418 - A418
    01/01/1984 Authors: HEIDEMANN SR; JOSHI HC
  • TENSION, COMPRESSION AND THE CYTOSKELETON OF PC-12 NEURITES
    JOURNAL OF CELL BIOLOGY Volume: 99 Page(s): A32 - A32
    01/01/1984 Authors: JOSHI HC; CHU D; HEIDEMANN SR
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