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Profile

Mark Czaja MD, FAASLD

  • Department of Medicine
    Adjunct Professor
  • (404) 727-4842
  • Emory University School of Medicine
    Medicine
    615 Michael St. Suite 201
Head shot of Mark Czaja

Overview

Mark J. Czaja, MD, FAASLD is a professor of medicine in the Division of Digestive Diseases at the Emory University School of Medicine. Dr. Czaja completed his undergraduate education at Yale University and received an MD from Columbia University. He completed internal medicine clinical training at Case Western Reserve University and gastroenterology/hepatology clinical training at the Albert Einstein College of Medicine. After doing postdoctoral research on hepatic fibrosis at Einstein, Dr. Czaja joined their faculty, where he remained for a number of years before assuming his present position at Emory.

Dr. Czaja's National Institutes of Health (NIH)-funded research attempts to understand the mechanisms of liver injury and hepatocyte death in order to develop new therapeutic approaches to prevent human liver failure. These investigations have defined signal transduction pathways that mediate liver injury from inflammatory factors such as the cytokine tumor necrosis factor and oxidants during toxin-induced liver injury, and regulate the development of steatosis and the progression to steatohepatitis in fatty liver disease. His laboratory first described the metabolism of endogenous cellular lipids through the lysosomal pathway of autophagy, and additional work in his laboratory has delineated functions for autophagy in both hepatocytes and macrophages that limit liver injury.

Dr. Czaja has held numerous positions, including associate editor and editorial board member of major scientific journals as well as chair or member on NIH study sections and national committees. He has served on the Governing Board of the American Association for the Study of Liver Diseases. He is an elected member of the Association of American Physicians as well as a Fellow of the American Association for the Study of Liver Diseases.

Academic Appointment

  • Professor of Medicine, Department of Medicine - Division of Digestive Diseases, Emory University

Education

Degrees

  • MD from Columbia University
  • BA from Yale University

Research

Publications

  • Glial cell derived neurotrophic factor prevents western diet and palmitate-induced hepatocyte oxidative damage and death through SIRT3.
    Sci Rep Volume: 12 Page(s): 15838
    09/23/2022 Authors: Mwangi SM; Li G; Balasubramaniam A; Merlin D; Dawson PA; Jang YC; Hart CM; Czaja MJ; Srinivasan S
  • Integrated regulation of stress responses, autophagy and survival by altered intracellular iron stores.
    Redox Biol Volume: 55 Page(s): 102407
    09/01/2022 Authors: Wang Y; Wang M; Liu Y; Tao H; Banerjee S; Srinivasan S; Nemeth E; Czaja MJ; He P
  • Redundant Functions of ERK1 and ERK2 Maintain Mouse Liver Homeostasis Through Down-Regulation of Bile Acid Synthesis.
    Hepatol Commun Volume: 6 Page(s): 980 - 994
    05/01/2022 Authors: Cingolani F; Liu Y; Shen Y; Wen J; Farris AB; Czaja MJ
  • Mouse liver injury induces hepatic macrophage FGF23 production.
    PLoS One Volume: 17 Page(s): e0264743
    01/01/2022 Authors: Kumar P; Liu Y; Shen Y; Maher JJ; Cingolani F; Czaja MJ
  • Sex-Specific Regulation of Interferon- Cytotoxicity in Mouse Liver by Autophagy.
    Hepatology Volume: 74 Page(s): 2745 - 2758
    11/01/2021 Authors: Shen Y; Cingolani F; Malik SA; Wen J; Liu Y; Czaja MJ
  • GLIAL CELL DERIVED NEUROTROPHIC FACTOR PREVENTS PALMITATE-INDUCED OXIDATIVE STRESS AND SUPPRESSION OF MITOPHAGY IN HEPATOCYTES BY INCREASING SIRT3 LEVELS
    Volume: 160 Page(s): S64 - S64
    05/01/2021 Authors: Mwangi SM; Li G; Chandramowlishwaran P; Liu Y; Hart CM; Merlin D; Czaja MJ; Srinivasan S
  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
    Autophagy Volume: 17 Page(s): 1 - 382
    01/01/2021 Authors: Klionsky DJ; Abdel-Aziz AK; Abdelfatah S; Abdellatif M; Abdoli A; Abel S; Abeliovich H; Abildgaard MH; Abudu YP; Acevedo-Arozena A
  • Blocking integrin 47-mediated CD4 T cell recruitment to the intestine and liver protects mice from western diet-induced non-alcoholic steatohepatitis.
    J Hepatol Volume: 73 Page(s): 1013 - 1022
    11/01/2020 Authors: Rai RP; Liu Y; Iyer SS; Liu S; Gupta B; Desai C; Kumar P; Smith T; Singhi AD; Nusrat A
  • Decreased Hepatocyte Autophagy Leads to Synergistic IL-1 and TNF Mouse Liver Injury and Inflammation.
    Hepatology Volume: 72 Page(s): 595 - 608
    08/01/2020 Authors: Shen Y; Malik SA; Amir M; Kumar P; Cingolani F; Wen J; Liu Y; Zhao E; Farris AB; Raeman R
  • Stathmin 1 Induces Murine Hepatocyte Proliferation and Increased Liver Mass.
    Hepatol Commun Volume: 4 Page(s): 38 - 49
    01/01/2020 Authors: Zhao E; Shen Y; Amir M; Farris AB; Czaja MJ
  • Acetaminophen Intoxication Rapidly Induces Apoptosis of Intestinal Crypt Stem Cells and Enhances Intestinal Permeability.
    Hepatol Commun Volume: 3 Page(s): 1435 - 1449
    11/01/2019 Authors: Chopyk DM; Stuart JD; Zimmerman MG; Wen J; Gumber S; Suthar MS; Thapa M; Czaja MJ; Grakoui A
  • DECREASED HEPATOCYTE AUTOPHAGY PROMOTES SYNERGISTIC INTERLEUKIN-1 beta AND TUMOR NECROSIS FACTOR HEPATOTOXICITY AND INFLAMMATION IN MICE
    Volume: 70 Page(s): 139A - 139A
    10/01/2019 Authors: Shen Y; Malik SA; Amir M; Kumar P; Cingolani F; Liu Y; Czaja MJ
  • Decreased Macrophage Autophagy Promotes Liver Injury and Inflammation from Alcohol.
    Alcohol Clin Exp Res Volume: 43 Page(s): 1403 - 1413
    07/01/2019 Authors: Ilyas G; Cingolani F; Zhao E; Tanaka K; Czaja MJ
  • Glial Cell Line-Derived Neurotrophic Factor Enhances Autophagic Flux in Mouse and Rat Hepatocytes and Protects Against Palmitate Lipotoxicity.
    Hepatology Volume: 69 Page(s): 2455 - 2470
    06/01/2019 Authors: Mwangi SM; Li G; Ye L; Liu Y; Reichardt F; Yeligar SM; Hart CM; Czaja MJ; Srinivasan S
  • A Novel Mechanism of Starvation-Stimulated Hepatic Autophagy: Calcium-Induced O-GlcNAc-Dependent Signaling.
    Hepatology Volume: 69 Page(s): 446 - 448
    01/01/2019 Authors: Shen Y; Czaja MJ
  • Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap.
    Nat Commun Volume: 9 Page(s): 4962
    11/23/2018 Authors: Lee YA; Noon LA; Akat KM; Ybanez MD; Lee T-F; Berres M-L; Fujiwara N; Goossens N; Chou H-I; Parvin-Nejad FP
  • Oxidized Albumin-A Trojan Horse for p38 MAPK-Mediated Inflammation in Decompensated Cirrhosis.
    Hepatology Volume: 68 Page(s): 1678 - 1680
    11/01/2018 Authors: Cingolani F; Czaja MJ
  • Inflammasome-mediated inflammation and fibrosis: It is more than just the IL-1.
    Hepatology Volume: 67 Page(s): 479 - 481
    02/01/2018 Authors: Amir M; Czaja MJ
  • Pentamidine blocks hepatotoxic injury in mice.
    Hepatology Volume: 66 Page(s): 922 - 935
    09/01/2017 Authors: Zhao E; Ilyas G; Cingolani F; Choi JH; Ravenelle F; Tanaka KE; Czaja MJ
  • GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR REVERSES HIGH FAT DIET-INDUCED SUPPRESSION OF HEPATIC AUTOPHAGY AND ENHANCES HEPATOCYTE MITOCHONDRIAL FATTY ACID OXIDATION AND SURVIVAL
    Volume: 152 Page(s): S1069 - S1069
    04/01/2017 Authors: Mwangi SM; Li G; Reichardt F; Hart CM; Czaja MJ; Srinivasan S
  • Fibroblast growth factor 23 directly targets hepatocytes to promote inflammation in chronic kidney disease.
    Kidney Int Volume: 90 Page(s): 985 - 996
    11/01/2016 Authors: Singh S; Grabner A; Yanucil C; Schramm K; Czaya B; Krick S; Czaja MJ; Bartz R; Abraham R; Di Marco GS
  • Regulation and Functions of Autophagic Lipolysis.
    Trends Endocrinol Metab Volume: 27 Page(s): 696 - 705
    10/01/2016 Authors: Cingolani F; Czaja MJ
  • Autophagy confers resistance to lipopolysaccharide-induced mouse hepatocyte injury.
    Am J Physiol Gastrointest Liver Physiol Volume: 311 Page(s): G377 - G386
    09/01/2016 Authors: Lalazar G; Ilyas G; Malik SA; Liu K; Zhao E; Amir M; Lin Y; Tanaka KE; Czaja MJ
  • Function of Autophagy in Nonalcoholic Fatty Liver Disease.
    Dig Dis Sci Volume: 61 Page(s): 1304 - 1313
    05/01/2016 Authors: Czaja MJ
  • Erratum.
    Autophagy Volume: 12 Page(s): 443
    01/01/2016
  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
    Autophagy Volume: 12 Page(s): 1 - 222
    01/01/2016 Authors: Klionsky DJ; Abdelmohsen K; Abe A; Abedin MJ; Abeliovich H; Acevedo Arozena A; Adachi H; Adams CM; Adams PD; Adeli K
  • Macrophage autophagy limits acute toxic liver injury in mice through down regulation of interleukin-1.
    J Hepatol Volume: 64 Page(s): 118 - 127
    01/01/2016 Authors: Ilyas G; Zhao E; Liu K; Lin Y; Tesfa L; Tanaka KE; Czaja MJ
  • A new mechanism of lipotoxicity: Calcium channel blockers as a treatment for nonalcoholic steatohepatitis?
    Hepatology Volume: 62 Page(s): 312 - 314
    07/01/2015 Authors: Czaja MJ
  • Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization.
    Autophagy Volume: 11 Page(s): 271 - 284
    01/01/2015 Authors: Liu K; Zhao E; Ilyas G; Lalazar G; Lin Y; Haseeb M; Tanaka KE; Czaja MJ
  • ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis.
    J Hepatol Volume: 61 Page(s): 1126 - 1134
    11/01/2014 Authors: Fucho R; Martnez L; Baulies A; Torres S; Tarrats N; Fernandez A; Ribas V; Astudillo AM; Balsinde J; Garcia-Rovs P
  • High-mobility group box 1 is dispensable for autophagy, mitochondrial quality control, and organ function in vivo.
    Cell Metab Volume: 19 Page(s): 539 - 547
    03/04/2014 Authors: Huebener P; Gwak G-Y; Pradere J-P; Quinzii CM; Friedman R; Lin C-S; Trent CM; Mederacke I; Zhao E; Dapito DH
  • Stathmin mediates hepatocyte resistance to death from oxidative stress by down regulating JNK.
    PLoS One Volume: 9 Page(s): e109750
    01/01/2014 Authors: Zhao E; Amir M; Lin Y; Czaja MJ
  • Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling.
    Redox Biol Volume: 3 Page(s): 7 - 15
    01/01/2014 Authors: Schattenberg JM; Czaja MJ
  • Reply: To PMID 23081825.
    Hepatology Volume: 58 Page(s): 831
    08/01/2013 Authors: Czaja MJ
  • Functions of autophagy in normal and diseased liver.
    Autophagy Volume: 9 Page(s): 1131 - 1158
    08/01/2013 Authors: Czaja MJ; Ding W-X; Donohue TM; Friedman SL; Kim J-S; Komatsu M; Lemasters JJ; Lemoine A; Lin JD; Ou J-HJ
  • Inhibition of hepatocyte autophagy increases tumor necrosis factor-dependent liver injury by promoting caspase-8 activation.
    Cell Death Differ Volume: 20 Page(s): 878 - 887
    07/01/2013 Authors: Amir M; Zhao E; Fontana L; Rosenberg H; Tanaka K; Gao G; Czaja MJ
  • Aging promotes the development of diet-induced murine steatohepatitis but not steatosis.
    Hepatology Volume: 57 Page(s): 995 - 1004
    03/01/2013 Authors: Fontana L; Zhao E; Amir M; Dong H; Tanaka K; Czaja MJ
  • Regulation of lipid stores and metabolism by lipophagy.
    Cell Death Differ Volume: 20 Page(s): 3 - 11
    01/01/2013 Authors: Liu K; Czaja MJ
  • Distinct functions of JNK and c-Jun in oxidant-induced hepatocyte death.
    J Cell Biochem Volume: 113 Page(s): 3254 - 3265
    10/01/2012 Authors: Amir M; Liu K; Zhao E; Czaja MJ
  • Transcription factor EB: a central regulator of both the autophagosome and lysosome.
    Hepatology Volume: 55 Page(s): 1632 - 1634
    05/01/2012 Authors: Zhao E; Czaja MJ
  • Guidelines for the use and interpretation of assays for monitoring autophagy.
    Autophagy Volume: 8 Page(s): 445 - 544
    04/01/2012 Authors: Klionsky DJ; Abdalla FC; Abeliovich H; Abraham RT; Acevedo-Arozena A; Adeli K; Agholme L; Agnello M; Agostinis P; Aguirre-Ghiso JA
  • Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues.
    Gastroenterology Volume: 142 Page(s): 938 - 946
    04/01/2012 Authors: Hernndez-Gea V; Ghiassi-Nejad Z; Rozenfeld R; Gordon R; Fiel MI; Yue Z; Czaja MJ; Friedman SL
  • Functions of autophagy in hepatic and pancreatic physiology and disease.
    Gastroenterology Volume: 140 Page(s): 1895 - 1908
    06/01/2011 Authors: Czaja MJ
  • Regulation of lipid droplets by autophagy.
    Trends Endocrinol Metab Volume: 22 Page(s): 234 - 240
    06/01/2011 Authors: Dong H; Czaja MJ
  • Autophagy in nonalcoholic steatohepatitis.
    Expert Rev Gastroenterol Hepatol Volume: 5 Page(s): 159 - 166
    04/01/2011 Authors: Amir M; Czaja MJ
  • Two types of autophagy are better than one during hepatocyte oxidative stress.
    Autophagy Volume: 7 Page(s): 96 - 97
    01/01/2011 Authors: Czaja MJ
  • JNK regulation of hepatic manifestations of the metabolic syndrome.
    Trends Endocrinol Metab Volume: 21 Page(s): 707 - 713
    12/01/2010 Authors: Czaja MJ
  • Nuclear factor B up-regulation of CCAAT/enhancer-binding protein mediates hepatocyte resistance to tumor necrosis factor toxicity.
    Hepatology Volume: 52 Page(s): 2118 - 2126
    12/01/2010 Authors: Wang Y; Singh R; Xiang Y; Greenbaum LE; Czaja MJ
  • AUTOPHAGY REGULATES HEPATIC STELLATE CELL ACTIVATION AND FIBROGENESIS
    Volume: 52 Page(s): 1261A - 1262A
    10/01/2010 Authors: Hernandez-Gea V; Ghiassi-Nejad Z; Gordon RE; Czaja MJ; Friedman SL
  • Macroautophagy and chaperone-mediated autophagy are required for hepatocyte resistance to oxidant stress.
    Hepatology Volume: 52 Page(s): 266 - 277
    07/01/2010 Authors: Wang Y; Singh R; Xiang Y; Czaja MJ
  • Autophagy in health and disease. 2. Regulation of lipid metabolism and storage by autophagy: pathophysiological implications.
    Am J Physiol Cell Physiol Volume: 298 Page(s): C973 - C978
    05/01/2010 Authors: Czaja MJ
  • Chronic oxidative stress sensitizes hepatocytes to death from 4-hydroxynonenal by JNK/c-Jun overactivation.
    Am J Physiol Gastrointest Liver Physiol Volume: 297 Page(s): G907 - G917
    11/01/2009 Authors: Singh R; Wang Y; Schattenberg JM; Xiang Y; Czaja MJ
  • Autophagy regulates adipose mass and differentiation in mice.
    J Clin Invest Volume: 119 Page(s): 3329 - 3339
    11/01/2009 Authors: Singh R; Xiang Y; Wang Y; Baikati K; Cuervo AM; Luu YK; Tang Y; Pessin JE; Schwartz GJ; Czaja MJ
  • Lipases in lysosomes, what for?
    Autophagy Volume: 5 Page(s): 866 - 867
    08/01/2009 Authors: Czaja MJ; Cuervo AM
  • Pioglitazone: more than just an insulin sensitizer.
    Hepatology Volume: 49 Page(s): 1427 - 1430
    05/01/2009 Authors: Czaja MJ
  • Autophagy regulates lipid metabolism.
    Nature Volume: 458 Page(s): 1131 - 1135
    04/30/2009 Authors: Singh R; Kaushik S; Wang Y; Xiang Y; Novak I; Komatsu M; Tanaka K; Cuervo AM; Czaja MJ
  • Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance.
    Hepatology Volume: 49 Page(s): 87 - 96
    01/01/2009 Authors: Singh R; Wang Y; Xiang Y; Tanaka KE; Gaarde WA; Czaja MJ
  • GENETIC PERTURBATIONS FOLLOWING ISCHEMIC PRECONDITIONING OF DONOR HEPATOCYTES ALTER THE CAPACITY OF TRANSPLANTED CELLS TO PROLIFERATE IN THE LIVER
    Volume: 48 Page(s): 648A - 648A
    10/01/2008 Authors: Kapoor S; Berishvili E; Joseph B; Bandi S; Singhania R; Singh R; Czaja MJ; Gupta S
  • HEPATOCYTES ARE DEPENDENT ON MACROAUTOPHAGY FOR RESISTANCE TO CELL DEATH FROM OXIDANT STRESS
    Volume: 48 Page(s): 325A - 326A
    10/01/2008 Authors: Wang Y; Singh R; Xiang Y; Czaja MJ
  • Compensatory mechanisms and the type of injury determine the fate of cells with impaired macroautophagy.
    Autophagy Volume: 4 Page(s): 516 - 518
    05/01/2008 Authors: Singh R; Czaja MJ
  • Regulation of hepatocyte apoptosis by oxidative stress (vol 22, pg S45, 2007)
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Volume: 23 Page(s): 501 - 501
    03/01/2008 Authors: Singh R; Czaja MJ
  • Loss of macroautophagy promotes or prevents fibroblast apoptosis depending on the death stimulus.
    J Biol Chem Volume: 283 Page(s): 4766 - 4777
    02/22/2008 Authors: Wang Y; Singh R; Massey AC; Kane SS; Kaushik S; Grant T; Xiang Y; Cuervo AM; Czaja MJ
  • Cell signaling in oxidative stress-induced liver injury.
    Semin Liver Dis Volume: 27 Page(s): 378 - 389
    11/01/2007 Authors: Czaja MJ
  • Differential effects of JNK1 and JNK2 on the development of steatohepatitis
    Volume: 46 Page(s): 306A - 306A
    10/01/2007 Authors: Singh R; Wang Y; Xiang Y; Tanaka K; Gaarde WA; Czaja MJ
  • Regulation of hepatocyte apoptosis by oxidative stress.
    Volume: 22 Suppl 1 Page(s): S45 - S48
    06/01/2007 Authors: Singh R; Czaja MJ
  • Down regulation of C/EBP beta expression by JNK mediates hepatocyte TNF toxicity
    Volume: 44 Page(s): 383A - 384A
    10/01/2006 Authors: Wang Y; Singh R; Xiang Y; Greenbaum LE; Czaja MJ
  • Cyp2E1-induced oxidative stress promotes triglyceride synthesis and cellular injury in the steatotic hepatocyte
    Volume: 44 Page(s): 243A - 243A
    10/01/2006 Authors: Singh R; Wang Y; Kane SS; Xiang Y; Silver DL; Czaja MJ
  • Tumor necrosis factor-induced toxic liver injury results from JNK2-dependent activation of caspase-8 and the mitochondrial death pathway.
    J Biol Chem Volume: 281 Page(s): 15258 - 15267
    06/02/2006 Authors: Wang Y; Singh R; Lefkowitch JH; Rigoli RM; Czaja MJ
  • JNK1 but not JNK2 promotes the development of steatohepatitis in mice.
    Hepatology Volume: 43 Page(s): 163 - 172
    01/01/2006 Authors: Schattenberg JM; Singh R; Wang Y; Lefkowitch JH; Rigoli RM; Scherer PE; Czaja MJ
  • Another way for NADPH oxidase to send a signal for liver injury.
    Gastroenterology Volume: 129 Page(s): 2110 - 2113
    12/01/2005 Authors: Czaja MJ
  • Capitalizing on AKT signaling to inhibit hepatocellular carcinoma cell proliferation.
    Cancer Biol Ther Volume: 4 Page(s): 1419 - 1421
    12/01/2005 Authors: Singh R; Czaja MJ
  • CYP2E1 overexpression sensitizes hepatocytes to JNK-dependent death from 4-hydroxynonenal
    Volume: 42 Page(s): 632A - 632A
    10/01/2005 Authors: Singh R; Wang YJ; Schattenberg JM; Rigoli RM; Czaja MJ
  • Toxic liver injury from GALN/LPS results from JNK2-dependent activation of the mitochondrial death pathway
    Volume: 42 Page(s): 251A - 251A
    10/01/2005 Authors: Wang YJ; Singh R; Lefkowitch JH; Rigoli RM; Czaja MJ
  • Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling.
    J Biol Chem Volume: 280 Page(s): 9887 - 9894
    03/18/2005 Authors: Schattenberg JM; Wang Y; Singh R; Rigoli RM; Czaja MJ
  • JNK1 promotes the development of steatohepatitis from a methionine choline deficient diet.
    Volume: 40 Page(s): 194A - 195A
    10/01/2004 Authors: Schattenberg JM; Wang YJ; Lefkowitch JH; Rigoli RM; Scherer PE; Czaja MJ
  • Hepatocyte resistance to oxidative stress is dependent on protein kinase C-mediated down-regulation of c-Jun/AP-1.
    J Biol Chem Volume: 279 Page(s): 31089 - 31097
    07/23/2004 Authors: Wang Y; Schattenberg JM; Rigoli RM; Storz P; Czaja MJ
  • Liver injury in the setting of steatosis: crosstalk between adipokine and cytokine.
    Hepatology Volume: 40 Page(s): 19 - 22
    07/01/2004 Authors: Czaja MJ
  • Proapoptotic function of protein kinase CK2alpha" is mediated by a JNK signaling cascade.
    Am J Physiol Gastrointest Liver Physiol Volume: 287 Page(s): G192 - G201
    07/01/2004 Authors: Hilgard P; Czaja MJ; Gerken G; Stockert RJ
  • CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling.
    Hepatology Volume: 39 Page(s): 444 - 455
    02/01/2004 Authors: Schattenberg JM; Wang Y; Rigoli RM; Koop DR; Czaja MJ
  • Pro-apoptotic role of cason Kinase 2 is mediated by a JNK signaling cascade.
    Volume: 38 Page(s): 241A - 241A
    10/01/2003 Authors: Hilgard P; Gerken G; Czaja MJ; Stockert RJ
  • Hepatic insulin signaling is inhibited by CYP2E1-overexpression.
    Volume: 38 Page(s): 192A - 192A
    10/01/2003 Authors: Schattenberg JM; Wang YJ; Rigoli RM; Czaja MJ
  • Hepatocyte resistance to oxidative stress is dependent on PKC - Mediated down-regulation of JNK/AP-1.
    Volume: 38 Page(s): 234A - 234A
    10/01/2003 Authors: Wang YJ; Schattenberg JM; Rigoli RM; Czaja MJ
  • The future of GI and liver research: editorial perspectives. III. JNK/AP-1 regulation of hepatocyte death.
    Am J Physiol Gastrointest Liver Physiol Volume: 284 Page(s): G875 - G879
    06/01/2003 Authors: Czaja MJ
  • Oxidant-induced hepatocyte injury from menadione is regulated by ERK and AP-1 signaling.
    Hepatology Volume: 37 Page(s): 1405 - 1413
    06/01/2003 Authors: Czaja MJ; Liu H; Wang Y
  • CYP2E1 expression sensitizes hepatocytes to death from polyunsaturated fatty acids through ERK signaling
    Volume: 124 Page(s): A706 - A707
    04/01/2003 Authors: Schattenberg JM; Wang YJ; Rigoli RM; Czaja MJ
  • TNF-alpha and cell signaling in hepatocyte killing by xenobiotlc agents
    Volume: 35 Page(s): 2 - 2
    01/01/2003 Authors: Czaja MJ
  • Cytochrome P450 2E1 expression induces hepatocyte resistance to cell death from oxidative stress.
    Antioxid Redox Signal Volume: 4 Page(s): 701 - 709
    10/01/2002 Authors: Jones BE; Liu H; Lo CR; Koop DR; Czaja MJ
  • Hepatocyte resistance to oxidative injury results from ERK-dependent inhibition of JNK activation.
    Volume: 36 Page(s): 300A - 300A
    10/01/2002 Authors: Czaja MJ; Liu HL
  • Induction and regulation of hepatocyte apoptosis by oxidative stress.
    Antioxid Redox Signal Volume: 4 Page(s): 759 - 767
    10/01/2002 Authors: Czaja MJ
  • Protein kinase CK2 mediates hepatocyte apoptosis.
    Volume: 36 Page(s): 323A - 323A
    10/01/2002 Authors: Hilgard P; Czaja MJ; Stockert RJ; Gerken G
  • NF-kappaB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun.
    Hepatology Volume: 35 Page(s): 772 - 778
    04/01/2002 Authors: Liu H; Lo CR; Czaja MJ
  • Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun-mediated cell death from TNF-alpha.
    Am J Physiol Gastrointest Liver Physiol Volume: 282 Page(s): G257 - G266
    02/01/2002 Authors: Liu H; Jones BE; Bradham C; Czaja MJ
  • Induction of cyclooxygenase-2 by tumor promoters in transformed and cytochrome P450 2E1-expressing hepatocytes.
    Carcinogenesis Volume: 23 Page(s): 73 - 79
    01/01/2002 Authors: de Ldinghen V; Liu H; Zhang F; Lo CR; Subbaramaiah K; Dannenberg AJ; Czaja MJ
  • TNF toxicity--death from caspase or cathepsin, that is the question.
    Hepatology Volume: 34 Page(s): 844 - 846
    10/01/2001 Authors: Czaja MJ
  • TNF toxicity - Death from caspase or cathepsin, that is the question
    HEPATOLOGY Volume: 34 Page(s): 844 - 846
    10/01/2001 Authors: Czaja MJ
  • NF-kappa B inhibition sensitizes hepatocytes to TNF-alpha-induced apoptosis through a sustained activation of JNK and c-Jun.
    Volume: 34 Page(s): 248A - 248A
    10/01/2001 Authors: Liu HL; Lo CR; Czaja MJ
  • Direct hepatotoxicity and cytoprotection
    HEPATOLOGY Volume: 33 Page(s): 1009 - 1010
    04/01/2001 Authors: Malet PF; Wendel A; Czaja MJ; Voellmy R; Guengerich FP; Gores GJ; Leeder JS
  • Inhibition of c-Myc expression sensitizes hepatocytes to tumor necrosis factor-induced apoptosis and necrosis.
    J Biol Chem Volume: 275 Page(s): 40155 - 40162
    12/22/2000 Authors: Liu H; Lo CR; Jones BE; Pradhan Z; Srinivasan A; Valentino KL; Stockert RJ; Czaja MJ
  • Cyclooxygenase-2 is induced by phorbol ester in transformed and CYP2E1-expressing hepatocytes.
    Volume: 32 Page(s): 325A - 325A
    10/01/2000 Authors: de Ledinghen V; Zhang F; Liu HL; Rubashevsky E; Subbaramaiah K; Dannenberg AJ; Czaja MJ
  • Increased cytochrome p450 2E1 (CYP2E1) expression sensitizes hepatocytes to TNF-A-induced cell death.
    Volume: 32 Page(s): 304A - 304A
    10/01/2000 Authors: Liu HL; Rubashevsky E; Jones BE; Czaja MJ
  • Resistance of the casein kinase deficient hepatoma cell line trf1 to dengue virus-induced cell death.
    Volume: 32 Page(s): 215A - 215A
    10/01/2000 Authors: Hilgard P; Czaja MJ; Stockert RJ
  • Role of caspases and NF-kappaB signaling in hydrogen peroxide- and superoxide-induced hepatocyte apoptosis.
    Am J Physiol Gastrointest Liver Physiol Volume: 278 Page(s): G693 - G699
    05/01/2000 Authors: Jones BE; Lo CR; Liu H; Pradhan Z; Garcia L; Srinivasan A; Valentino KL; Czaja MJ
  • Hepatocytes sensitized to tumor necrosis factor-alpha cytotoxicity undergo apoptosis through caspase-dependent and caspase-independent pathways.
    J Biol Chem Volume: 275 Page(s): 705 - 712
    01/07/2000 Authors: Jones BE; Lo CR; Liu H; Srinivasan A; Streetz K; Valentino KL; Czaja MJ
  • Cytochrome P4502E1 (CYP2E1) expression induces hepatocyte resistance to the TNF-alpha and reactive oxygen intermediate induced cell death
    Volume: 30 Page(s): 412A - 412A
    10/01/1999 Authors: Jones BE; Lo CR; Czaja MJ
  • Inhibition of c-Myc expression sensitizes hepatocytes to TNF-alpha-induced cell death
    Volume: 30 Page(s): 416A - 416A
    10/01/1999 Authors: Liu H; Lo CR; Jones BE; Pradhan Z; Stockert RJ; Czaja MJ
  • Ceramide induces caspase-independent apoptosis in rat hepatocytes sensitized by inhibition of RNA synthesis.
    Hepatology Volume: 30 Page(s): 215 - 222
    07/01/1999 Authors: Jones BE; Lo CR; Srinivasan A; Valentino KL; Czaja MJ
  • Copper resistant human hepatoblastoma mutant cell lines without metallothionein induction overexpress ATP7B.
    Hepatology Volume: 28 Page(s): 1347 - 1356
    11/01/1998 Authors: Schilsky ML; Stockert RJ; Kesner A; Gorla GR; Gagliardi GS; Terada K; Miura N; Czaja MJ
  • Glutathione modulates rat and mouse hepatocyte sensitivity to tumor necrosis factor toxicity.
    Gastroenterology Volume: 115 Page(s): 1229 - 1237
    11/01/1998 Authors: Xu Y; Jones BE; Neufeld DS; Czaja MJ
  • III. Intracellular signaling in response to toxic liver injury.
    Am J Physiol Volume: 275 Page(s): G874 - G878
    11/01/1998 Authors: Jones BE; Czaja MJ
  • NF-kappa B inactivation and actinomycin D sensitize hepatocytes to TNF-alpha cytotoxicity by different mechanisms.
    Volume: 28 Page(s): 391A - 391A
    10/01/1998 Authors: Jones BE; Streetz K; Srinivasan A; Valentino KL; Brenner DA; Czaja MJ
  • Hepatocytes are resistant to ceramide toxicity.
    Volume: 28 Page(s): 322A - 322A
    10/01/1998 Authors: Jones BE; Srinivasan A; Valentino KL; Czaja MJ
  • Caspases mediate hydrogen peroxide but not superoxide induced hepatocyte apoptosis.
    Volume: 28 Page(s): 310A - 310A
    10/01/1998 Authors: Jones BE; Garcia L; Pradhan Z; Srinivasan A; Valentino KL; Czaja MJ
  • NF-kappaB inactivation converts a hepatocyte cell line TNF-alpha response from proliferation to apoptosis.
    Am J Physiol Volume: 275 Page(s): C1058 - C1066
    10/01/1998 Authors: Xu Y; Bialik S; Jones BE; Iimuro Y; Kitsis RN; Srinivasan A; Brenner DA; Czaja MJ
  • Hepatocyte sensitization to TNF-alpha cytotoxicity is mediated by NF-kappa B.
    Volume: 26 Page(s): 243 - 243
    10/01/1997 Authors: Xu Y; Iimuro Y; Brenner DA; Czaja MJ
  • Hydrogen peroxide-induced liver cell necrosis is dependent on AP-1 activation.
    Am J Physiol Volume: 273 Page(s): G795 - G803
    10/01/1997 Authors: Xu Y; Bradham C; Brenner DA; Czaja MJ
  • c-myc-Dependent hepatoma cell apoptosis results from oxidative stress and not a deficiency of growth factors.
    J Cell Physiol Volume: 170 Page(s): 192 - 199
    02/01/1997 Authors: Xu Y; Nguyen Q; Lo DC; Czaja MJ
  • Mutant HuH-7 cell lines resistant to copper toxicity overexpress the Wilson's disease gene (ATP7B).
    Volume: 24 Page(s): 493 - 493
    10/01/1996 Authors: Schilsky ML; Stockert RJ; Reddy GG; Gagliardi GS; Czaja MJ
  • Hydrogen peroxide induced liver cell necrosis is dependent on AP-1 activation.
    Volume: 24 Page(s): 440 - 440
    10/01/1996 Authors: Xu Y; Bradham CA; Brenner DA; Czaja MJ
  • Glutathione (GSH) depletion sensitizes liver cells to TNF-alpha cytotoxicity.
    Volume: 24 Page(s): 238 - 238
    10/01/1996 Authors: Xu Y; Czaja MJ
  • Regulation of monocyte chemoattractant protein 1 by cytokines and oxygen free radicals in rat hepatic fat-storing cells.
    Gastroenterology Volume: 110 Page(s): 1870 - 1877
    06/01/1996 Authors: Xu Y; Rojkind M; Czaja MJ
  • Induction of hepatoma cell apoptosis by c-myc requires zinc and occurs in the absence of DNA fragmentation.
    Am J Physiol Volume: 270 Page(s): G60 - G70
    01/01/1996 Authors: Xu J; Xu Y; Nguyen Q; Novikoff PM; Czaja MJ
  • C-MYC INDUCTION OF HEPATOMA-CELL APOPTOSIS UNDER SERUM-FREE CONDITIONS IS MEDIATED BY OXIDATIVE STRESS
    Volume: 22 Page(s): 485 - 485
    10/01/1995 Authors: CZAJA MJ; XU Y; NGUYEN O
  • Prevention of carbon tetrachloride-induced rat liver injury by soluble tumor necrosis factor receptor.
    Gastroenterology Volume: 108 Page(s): 1849 - 1854
    06/01/1995 Authors: Czaja MJ; Xu J; Alt E
  • MONOCYTE CHEMOATTRACTANT PROTEIN-1 (MCP-1) PRODUCTION BY FAT-STORING CELLS IS INCREASED BY CYTOKINES AND OXYGEN-FREE RADICALS
    Volume: 20 Page(s): A269 - A269
    10/01/1994 Authors: XU Y; ROJKIND M; CZAJA MJ
  • THE INDUCTION OF HEPATOMA-CELL APOPTOSIS BY C-MYC IS TRIGGERED BY ZINC AND OCCURS IN THE ABSENCE OF DNA FRAGMENTATION
    Volume: 20 Page(s): A208 - A208
    10/01/1994 Authors: XU J; XU Y; NOVIKOFF PM; CZAJA MJ
  • Lipopolysaccharide-neutralizing antibody reduces hepatocyte injury from acute hepatotoxin administration.
    Hepatology Volume: 19 Page(s): 1282 - 1289
    05/01/1994 Authors: Czaja MJ; Xu J; Ju Y; Alt E; Schmiedeberg P
  • INDUCTION OF MNSOD GENE-EXPRESSION IN A HEPATIC MODEL OF TNF-ALPHA TOXICITY DOES NOT RESULT IN INCREASED PROTEIN
    AMERICAN JOURNAL OF PHYSIOLOGY Volume: 266 Page(s): G737 - G744
    04/01/1994 Authors: CZAJA MJ; SCHILSKY ML; XU Y; SCHMIEDEBERG P; COMPTON A; RIDNOUR L; OBERLEY LW
  • Induction of MnSOD gene expression in a hepatic model of TNF-alpha toxicity does not result in increased protein.
    Am J Physiol Volume: 266 Page(s): G737 - G744
    04/01/1994 Authors: Czaja MJ; Schilsky ML; Xu Y; Schmiedeberg P; Compton A; Ridnour L; Oberley LW
  • Monocyte chemoattractant protein 1 (MCP-1) expression occurs in toxic rat liver injury and human liver disease.
    J Leukoc Biol Volume: 55 Page(s): 120 - 126
    01/01/1994 Authors: Czaja MJ; Geerts A; Xu J; Schmiedeberg P; Ju Y
  • TREATMENT WITH SOLUBLE TUMOR-NECROSIS-FACTOR-ALPHA RECEPTOR (STNFR) REDUCES TOXIC LIVER-INJURY
    Volume: 18 Page(s): A111 - A111
    10/01/1993 Authors: CZAJA MJ; XU J; JU Y; ALT E
  • HEPATOCYTE APOPTOSIS IS TRIGGERED BY GALACTOSAMINE OR CYCLOHEXIMIDE, AND ASSOCIATED WITH EXPRESSION OF THE RP-8 GENE
    Volume: 18 Page(s): A133 - A133
    10/01/1993 Authors: CZAJA MJ; XU J; JU Y; ALT E
  • Timing of protooncogene expression varies in toxin-induced liver regeneration.
    J Cell Physiol Volume: 154 Page(s): 294 - 300
    02/01/1993 Authors: Schmiedeberg P; Biempica L; Czaja MJ
  • EXPRESSION OF THE PROTOONCOGENE C-MYC CAN LEAD TO LIVER-CELL DEATH
    Volume: 16 Page(s): A136 - A136
    10/01/1992 Authors: CZAJA MJ; JU Y
  • TOXIC INJURY SENSITIZES HEPATOMA-CELLS TO CYTOTOXICITY FROM TNF-ALPHA AND IL-1
    Volume: 16 Page(s): A267 - A267
    10/01/1992 Authors: CZAJA MJ; SCHMIEDEBERG P; JU Y; LEVOWITZ Y
  • COPPER EXPOSURE INDUCES A STRESS RESPONSE IN HEPG2
    Volume: 16 Page(s): A269 - A269
    10/01/1992 Authors: MOTEELALL MK; SCHILSKY ML; CZAJA MJ; STERNLIEB I; STOCKERT RJ
  • Ito cell expression of a nuclear retinoic acid receptor.
    Hepatology Volume: 15 Page(s): 336 - 342
    02/01/1992 Authors: Weiner FR; Blaner WS; Czaja MJ; Shah A; Geerts A
  • The effects of hepatic fibrosis on Ito cell gene expression.
    Matrix Volume: 12 Page(s): 36 - 43
    02/01/1992 Authors: Weiner FR; Shah A; Biempica L; Zern MA; Czaja MJ
  • THE REGULATION OF HEPATIC MATRIX PROTEIN-SYNTHESIS BY CYTOKINES
    Volume: 216 Page(s): 147 - 156
    01/01/1992 Authors: WEINER FR; ESPOSTI SD; CZAJA MJ; ZERN MA
  • LPS-NEUTRALIZING ANTIBODIES REDUCE ACUTE LIVER-INJURY WITHOUT AFFECTING CYTOKINE GENE-EXPRESSION
    Volume: 14 Page(s): A158 - A158
    10/01/1991 Authors: CZAJA MJ; KLEIN C; SCHMIEDEBERG P
  • Amplification of the metallothionein-1 and metallothionein-2 genes in copper-resistant hepatoma cells.
    J Cell Physiol Volume: 147 Page(s): 434 - 438
    06/01/1991 Authors: Czaja MJ; Weiner FR; Freedman JH
  • JE-GENE ACTIVATION OCCURS IN HEPATOTOXIC LIVER-DISEASE
    Volume: 12 Page(s): 932 - 932
    10/01/1990 Authors: CZAJA MJ; SCHMIEDEBERG P; KLEIN C
  • GALACTOSAMINE LIVER-INJURY BLOCKS A CELLULAR PROTECTIVE RESPONSE TO TUMOR-NECROSIS-FACTOR-ALPHA TOXICITY
    Volume: 12 Page(s): 903 - 903
    10/01/1990 Authors: SCHMIEDEBERG P; KLEIN C; CZAJA MJ
  • Albumin and collagen gene regulation in alcohol- and virus-induced human liver disease.
    Gastroenterology Volume: 98 Page(s): 197 - 202
    01/01/1990 Authors: Annoni G; Weiner FR; Colombo M; Czaja MJ; Zern MA
  • Ito-cell gene expression and collagen regulation.
    Hepatology Volume: 11 Page(s): 111 - 117
    01/01/1990 Authors: Weiner FR; Giambrone MA; Czaja MJ; Shah A; Annoni G; Takahashi S; Eghbali M; Zern MA
  • Gamma-interferon treatment inhibits collagen deposition in murine schistosomiasis.
    Hepatology Volume: 10 Page(s): 795 - 800
    11/01/1989 Authors: Czaja MJ; Weiner FR; Takahashi S; Giambrone MA; van der Meide PH; Schellekens H; Biempica L; Zern MA
  • Hepatocellular copper toxicity and its attenuation by zinc.
    J Clin Invest Volume: 84 Page(s): 1562 - 1568
    11/01/1989 Authors: Schilsky ML; Blank RR; Czaja MJ; Zern MA; Scheinberg IH; Stockert RJ; Sternlieb I
  • EFFECTS OF TRANSFORMING GROWTH FACTOR-BETA-1 (TGF-BETA-1) ON ITO CELL EXTRACELLULAR-MATRIX GENE-EXPRESSION
    Volume: 10 Page(s): 682 - 682
    10/01/1989 Authors: WEINER FR; SHAH A; CZAJA MJ; GIAMBRONE MA; ZERN MA
  • CELLULAR SOURCES OF INCREASED COLLAGEN AND TRANSFORMING GROWTH FACTOR-BETA-1 GENE-EXPRESSION IN FIBROTIC RAT-LIVER
    Volume: 10 Page(s): 629 - 629
    10/01/1989 Authors: WEINER FR; SHAH A; BIEMPICA L; ZERN MA; CZAJA MJ
  • PROTO-ONCOGENE EXPRESSION VARIES IN DIFFERENT FORMS OF LIVER REPAIR
    Volume: 10 Page(s): 622 - 622
    10/01/1989 Authors: CZAJA MJ; KLEIN C; THOMPSON E; BIEMPICA L
  • In vitro and in vivo association of transforming growth factor-beta 1 with hepatic fibrosis.
    J Cell Biol Volume: 108 Page(s): 2477 - 2482
    06/01/1989 Authors: Czaja MJ; Weiner FR; Flanders KC; Giambrone MA; Wind R; Biempica L; Zern MA
  • Expression of tumor necrosis factor-alpha and transforming growth factor-beta 1 in acute liver injury.
    Growth Factors Volume: 1 Page(s): 219 - 226
    01/01/1989 Authors: Czaja MJ; Flanders KC; Biempica L; Klein C; Zern MA; Weiner FR
  • DIFFERENTIAL EXPRESSION OF TUMOR NECROSIS FACTOR-ALPHA AND TRANSFORMING GROWTH FACTOR-BETA-1 IN ACUTE LIVER-INJURY
    Volume: 8 Page(s): 1234 - 1234
    09/01/1988 Authors: CZAJA MJ; FLANDERS KC; BIEMPICA L; ZERN MA; WEINER FR
  • MODULATORS OF ITO CELL COLLAGEN-SYNTHESIS
    Volume: 8 Page(s): 1253 - 1253
    09/01/1988 Authors: WEINER FR; GIAMBRONE MA; TAKAHASHI S; ANNONI G; CZAJA MJ; ZERN MA
  • CHRONIC ALCOHOL ABUSERS MAINTAIN NORMAL ALBUMIN MESSENGER-RNA LEVELS DURING THE DEVELOPMENT OF CIRRHOSIS
    Volume: 8 Page(s): 1239 - 1239
    09/01/1988 Authors: ANNONI G; WEINER FR; COLOMBO M; CZAJA MJ; ZERN MA
  • CHARACTERIZATION OF THE MOLECULAR PHENOTYPE OF ITO CELLS
    Volume: 8 Page(s): 1307 - 1307
    09/01/1988 Authors: WEINER FR; GIAMBRONE MA; THOMPSON E; CZAJA MJ; ZERN MA
  • INCREASED TRANSFORMING GROWTH FACTOR-BETA-1 (TGF-BETA-1) GENE-EXPRESSION IN HUMAN-LIVER DISEASE
    Volume: 8 Page(s): 1227 - 1227
    09/01/1988 Authors: ANNONI G; CZAJA MJ; WEINER FR; ZERN MA
  • METALLOTHIONEIN GENE AMPLIFICATION IN COPPER-RESISTANT HEPATOMA-CELLS
    Volume: 8 Page(s): 1241 - 1241
    09/01/1988 Authors: CZAJA MJ; WEINER FR; FREEDMAN JH
  • ZINC ATTENUATION OF HEPATOCELLULAR COPPER TOXICITY MAY BE MEDIATED BY METALLOTHIONEIN BIOSYNTHESIS
    Volume: 8 Page(s): 1338 - 1338
    09/01/1988 Authors: SCHILSKY ML; CZAJA MJ; SCHEINBERG IH; STOCKERT RJ; STERNLIEB I
  • Collagen chain mRNAs in isolated heart cells from young and adult rats.
    J Mol Cell Cardiol Volume: 20 Page(s): 267 - 276
    03/01/1988 Authors: Eghbali M; Czaja MJ; Zeydel M; Weiner FR; Zern MA; Seifter S; Blumenfeld OO
  • Molecular studies of ceruloplasmin deficiency in Wilson's disease.
    J Clin Invest Volume: 80 Page(s): 1200 - 1204
    10/01/1987 Authors: Czaja MJ; Weiner FR; Schwarzenberg SJ; Sternlieb I; Scheinberg IH; Van Thiel DH; LaRusso NF; Giambrone MA; Kirschner R; Koschinsky ML
  • Differential effects of gamma-interferon on collagen and fibronectin gene expression.
    J Biol Chem Volume: 262 Page(s): 13348 - 13351
    09/25/1987 Authors: Czaja MJ; Weiner FR; Eghbali M; Giambrone MA; Eghbali M; Zern MA
  • COPPER TOXICITY - INHIBITION OF PROTEIN-SYNTHESIS IS A POSTTRANSCRIPTIONAL EVENT
    Volume: 7 Page(s): 1051 - 1051
    09/01/1987 Authors: SCHILSKY ML; BLANK RR; CZAJA MJ; ZERN MA; SCHEINBERG IH; STOCKERT RJ; STERNLIEB I
  • TRANSFORMING GROWTH-FACTOR-BETA STIMULATES COLLAGEN-SYNTHESIS INVITRO, AND IS ELEVATED IN AN INVIVO MODEL OF HEPATIC-FIBROSIS
    Volume: 7 Page(s): 1028 - 1028
    09/01/1987 Authors: CZAJA MJ; WEINER FR; GIAMBRONE MA; ZERN MA
  • ANTIFIBROGENIC EFFECTS OF GAMMA-INTERFERON IN MURINE SCHISTOSOMIASIS
    Volume: 7 Page(s): 1047 - 1047
    09/01/1987 Authors: CZAJA MJ; WEINER FR; GIAMBRONE MA; TAKAHASHI S; BIEMPICA L; ZERN MA
  • The effects of dexamethasone on in vitro collagen gene expression.
    J Biol Chem Volume: 262 Page(s): 6955 - 6958
    05/25/1987 Authors: Weiner FR; Czaja MJ; Jefferson DM; Giambrone MA; Tur-Kaspa R; Reid LM; Zern MA
  • DIFFERENTIAL COLLAGEN EXPRESSION IN HEART-CELLS
    Volume: 46 Page(s): 2040 - 2040
    05/01/1987 Authors: EGHBALI M; CZAJA MJ; CHEPKO G; ZERN MA; SEIFTER S; BLUMENFELD OO
  • Transcriptional and posttranscriptional effects of dexamethasone on albumin and procollagen messenger RNAs in murine schistosomiasis.
    Biochemistry Volume: 26 Page(s): 1557 - 1562
    03/24/1987 Authors: Weiner FR; Czaja MJ; Giambrone MA; Takahashi S; Biempica L; Zern MA
  • DEXAMETHASONE INHIBITS COLLAGEN-SYNTHESIS BY A DIRECT EFFECT ON THE COLLAGEN GENE PROMOTER
    Page(s): 137 - 137
    01/01/1987 Authors: ZERN MA; CZAJA MJ; TURKASPA R; WEINER FR
  • Development of molecular hybridization technology to evaluate albumin and procollagen mRNA content in baboons and man.
    Hepatology Volume: 7 Page(s): 19S - 25S
    01/01/1987 Authors: Weiner FR; Czaja MJ; Giambrone MA; Wu CH; Wu GY; Zern MA
  • MOLECULAR STUDIES OF CERULOPLASMIN DEFICIENCY IN WILSONS-DISEASE
    Volume: 6 Page(s): 1200 - 1200
    09/01/1986 Authors: CZAJA MJ; WEINER FR; SCHWARZENBERG SJ; STERNLIEB I; SCHEINBERG IH; VANTHIEL D; KOSCHINSKY M; MACGILLIVRAY RTA; ZERN MA
  • EFFECTS OF GAMMA-INTERFERON ON COLLAGEN GENE-EXPRESSION
    Volume: 6 Page(s): 1199 - 1199
    09/01/1986 Authors: CZAJA MJ; WEINER FR; KIRWIN MS; ZERN MA
  • DEXAMETHASONE INHIBITS COLLAGEN-SYNTHESIS BY A DIRECT EFFECT ON THE COLLAGEN GENE PROMOTER
    Volume: 6 Page(s): 1198 - 1198
    09/01/1986 Authors: ZERN MA; CZAJA MJ; TURKASPA R; WEINER FR
  • TRANSCRIPTIONAL AND POSTTRANSCRIPTIONAL EFFECTS OF DEXAMETHASONE ON AN INVIVO MODEL OF FIBROGENESIS
    Volume: 6 Page(s): 437 - 437
    01/01/1986 Authors: ZERN MA; CZAJA MJ; GIAMBRONE MA; TAKAHASHI S; BIEMPICA L; WEINER FR
  • TRANSCRIPTIONAL AND POSTTRANSCRIPTIONAL EFFECTS OF DEXAMETHASONE ON AN INVIVO MODEL OF FIBROGENESIS
    Page(s): 200 - 200
    01/01/1986 Authors: ZERN MA; CZAJA MJ; TAKAHASHI S; WEINER FR
  • Bile duct carcinoma in an adolescent.
    Am J Gastroenterol Volume: 80 Page(s): 486 - 489
    06/01/1985 Authors: Czaja MJ; Goldfarb JP; Cho KC; Biempica L; Morehouse HT; Abelow A
  • TRANSCRIPTIONAL AND POSTTRANSCRIPTIONAL EFFECTS OF DEXAMETHASONE ON AN INVIVO MODEL OF FIBROGENESIS
    Volume: 5 Page(s): 1013 - 1013
    01/01/1985 Authors: WEINER FR; CZAJA MJ; GLAMBRONE MA; TAKAHASHI S; ZERN MA
  • THE EFFECT OF ETHANOL ON HEPATIC ALBUMIN AND COLLAGEN MESSENGER-RNA CONTENT IN BABOONS AND MAN
    Volume: 33 Page(s): A541 - A541
    01/01/1985 Authors: WEINER FR; CZAJA MJ; LEO MA; LIEBER CS; ZERN MA
  • CIMETIDINE AND SUCRALFATE IN BLEEDING ULCERS - REPLY
    AMERICAN JOURNAL OF GASTROENTEROLOGY Volume: 80 Page(s): 659 - 659
    01/01/1985 Authors: GOLDFARB JP; CZAJA MJ
  • A comparison of cimetidine and sucralfate in the treatment of bleeding peptic ulcers.
    Am J Gastroenterol Volume: 80 Page(s): 5 - 7
    01/01/1985 Authors: Goldfarb JP; Czaja MJ
  • CIMETIDINE (C) VS SUCRALFATE (S) FOR BLEEDING PEPTIC-ULCERS - PRELIMINARY-RESULTS
    Volume: 86 Page(s): 1092 - 1092
    01/01/1984 Authors: GOLDFARB JP; CZAJA MJ
  • Multispecific lymphoid cell surface receptors.
    Proc Natl Acad Sci U S A Volume: 74 Page(s): 1224 - 1228
    03/01/1977 Authors: Czaja MJ; Richards FF; Varga JM
  • Polyfunctional antibodies. Their biology and inheritance.
    Ann Immunol (Paris) Volume: 127 Page(s): 253 - 260
    01/01/1976 Authors: Czaja M; Richards FF; Varga JM
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