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Profile

M. Ammar Zafar

  • Department of Microbiology and Immunology
    Associate Professor
  • (404) 727-5969
  • ammar.zafar@emory.edu
Head shot of M. Ammar Zafar

Academic Appointment

  • Associate Professor, Microbiology and Immunology, Emory

Research

Publications

  • Mechanisms of bacterial host-to-host transmission.
    Microbiol Mol Biol Rev Page(s): e0025924
    07/01/2025 Authors: Zafar MA; Hernandez GE; Walker KA
  • Klebsiella pneumoniae employs a type VI secretion system to overcome microbiota-mediated colonization resistance.
    Nat Commun Volume: 16 Page(s): 940
    01/22/2025 Authors: Bray AS; Broberg CA; Hudson AW; Wu W; Nagpal RK; Islam M; Valencia-Bacca JD; Shahid F; Hernandez GE; Nutter NA
  • An Enteric Bacterial Infection Triggers Neuroinflammation and Neurobehavioral Impairment in 3xTg-AD Transgenic Mice.
    J Infect Dis Volume: 230 Page(s): S95 - S108
    09/10/2024 Authors: Park G; Kadyan S; Hochuli N; Salazar G; Laitano O; Chakrabarty P; Efron PA; Zafar MA; Wilber A; Nagpal R
  • Deciphering the gastrointestinal carriage of Klebsiella pneumoniae.
    Infect Immun Volume: 92 Page(s): e0048223
    09/10/2024 Authors: Bray AS; Zafar MA
  • Ethanolamine metabolism through two genetically distinct loci enables Klebsiella pneumoniae to bypass nutritional competition in the gut.
    PLoS Pathog Volume: 20 Page(s): e1012189
    05/01/2024 Authors: Barnes AJ; Bennett EF; Vezina B; Hudson AW; Hernandez GE; Nutter NA; Bray AS; Nagpal R; Wyres KL; Zafar MA
  • The Two-Component System YesMN Promotes Pneumococcal Host-to-Host Transmission and Regulates Genes Involved in Zinc Homeostasis.
    Infect Immun Volume: 91 Page(s): e0037522
    01/24/2023 Authors: Zafar MA; Costa-Terryl A; Young TM
  • Klebsiella pneumoniae l-Fucose Metabolism Promotes Gastrointestinal Colonization and Modulates Its Virulence Determinants.
    Infect Immun Volume: 90 Page(s): e0020622
    10/20/2022 Authors: Hudson AW; Barnes AJ; Bray AS; Ornelles DA; Zafar MA
  • MgrB-Dependent Colistin Resistance in Klebsiella pneumoniae Is Associated with an Increase in Host-to-Host Transmission.
    mBio Volume: 13 Page(s): e0359521
    04/26/2022 Authors: Bray AS; Smith RD; Hudson AW; Hernandez GE; Young TM; George HE; Ernst RK; Zafar MA
  • Animal Model To Study Klebsiella pneumoniae Gastrointestinal Colonization and Host-to-Host Transmission.
    Infect Immun Volume: 88
    10/19/2020 Authors: Young TM; Bray AS; Nagpal RK; Caudell DL; Yadav H; Zafar MA
  • Identification of Pneumococcal Factors Affecting Pneumococcal Shedding Shows that the dlt Locus Promotes Inflammation and Transmission.
    mBio Volume: 10
    06/18/2019 Authors: Zafar MA; Hammond AJ; Hamaguchi S; Wu W; Kono M; Zhao L; Weiser JN
  • Capsule Prolongs Survival of Streptococcus pneumoniae during Starvation.
    Infect Immun Volume: 86
    03/01/2018 Authors: Hamaguchi S; Zafar MA; Cammer M; Weiser JN
  • Capsule Type and Amount Affect Shedding and Transmission of Streptococcus pneumoniae.
    mBio Volume: 8
    08/22/2017 Authors: Zafar MA; Hamaguchi S; Zangari T; Cammer M; Weiser JN
  • Host-to-Host Transmission of Streptococcus pneumoniae Is Driven by Its Inflammatory Toxin, Pneumolysin.
    Cell Host Microbe Volume: 21 Page(s): 73 - 83
    01/11/2017 Authors: Zafar MA; Wang Y; Hamaguchi S; Weiser JN
  • Single Cell Bottlenecks in the Pathogenesis of Streptococcus pneumoniae.
    PLoS Pathog Volume: 12 Page(s): e1005887
    10/01/2016 Authors: Kono M; Zafar MA; Zuniga M; Roche AM; Hamaguchi S; Weiser JN
  • Infant Mouse Model for the Study of Shedding and Transmission during Streptococcus pneumoniae Monoinfection.
    Infect Immun Volume: 84 Page(s): 2714 - 2722
    09/01/2016 Authors: Zafar MA; Kono M; Wang Y; Zangari T; Weiser JN
  • Transcriptional occlusion caused by overlapping promoters.
    Proc Natl Acad Sci U S A Volume: 111 Page(s): 1557 - 1561
    01/28/2014 Authors: Zafar MA; Carabetta VJ; Mandel MJ; Silhavy TJ
  • Genetic evidence for a novel interaction between transcriptional activator SoxS and region 4 of the (70) subunit of RNA polymerase at class II SoxS-dependent promoters in Escherichia coli.
    J Mol Biol Volume: 407 Page(s): 333 - 353
    04/01/2011 Authors: Zafar MA; Sanchez-Alberola N; Wolf RE
  • Protein-protein interactions between sigma(70) region 4 of RNA polymerase and Escherichia coli SoxS, a transcription activator that functions by the prerecruitment mechanism: evidence for "off-DNA" and "on-DNA" interactions.
    J Mol Biol Volume: 401 Page(s): 13 - 32
    08/06/2010 Authors: Zafar MA; Shah IM; Wolf RE
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