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Profile

Michael Burke

  • Department of Medicine
    Associate Professor
  • michael.burke@emory.edu
Head shot of Michael Burke

Overview

Michael A. Burke, MD, is an assistant professor of medicine in the Division of Cardiology at Emory University. Dr. Burke specializes in congestive heart failure, heart transplantation, mechanical circulatory support and cardiac critical care. He completed medical school at Jefferson Medical College, followed by internal medicine and general cardiovascular diseases training at Northwestern University. While at Northwestern, he was a scholar in the Physician Scientist Training Program, studying pathophysiologic mechanisms underlying heart failure. Subsequently, he completed a fellowship in advanced heart failure and transplantation medicine at Brigham and Womens Hospital. Upon completion of his clinical training, Dr. Burke joined the Seidman Lab in the Department of Genetics at Harvard Medical School as a post-doctoral research fellow, where he studied the molecular signaling networks that underlie the development of heart failure. During this time, he was also on staff as a heart failure physician at the West Roxbury VA Medical Center.

Dr. Burkes research focuses on the molecular and genetic basis of cardiomyopathies and heart failure. In particular, he is actively engaged in research projects studying the epigenetic control of pathologic gene activation, the control of metabolic gene expression and the regulatory role played by cardiac fibroblasts and pro-fibrotic signaling in the progression to heart failure. Dr. Burke joined the faculty at Emory in 2016.

Academic Appointment

  • Assistant Professor of Medicine, Emory University School of Medicine

Education

Degrees

  • MD from Jefferson Medical College
  • BS from Villanova University

Research

Publications

  • Asymptomatic But Obstructive: Anticipating the Coming Storm.
    JACC Heart Fail Volume: 13 Page(s): 344 - 345
    02/01/2025 Authors: Bilen O; Burke MA
  • Dilated Cardiomyopathy: A Genetic Journey from Past to Future.
    Int J Mol Sci Volume: 25
    10/25/2024 Authors: Newman NA; Burke MA
  • REALM-DCM: A Phase 3, Multinational, Randomized, Placebo-Controlled Trial of ARRY-371797 in Patients With Symptomatic LMNA-Related Dilated Cardiomyopathy.
    Circ Heart Fail Volume: 17 Page(s): e011548
    07/01/2024 Authors: Garcia-Pavia P; Palomares JFR; Sinagra G; Barriales-Villa R; Lakdawala NK; Gottlieb RL; Goldberg RI; Elliott P; Lee P; Li H
  • 2024 AHA/ACC/AMSSM/HRS/PACES/SCMR Guideline for the Management of Hypertrophic Cardiomyopathy: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.
    Circulation Volume: 149 Page(s): e1239 - e1311
    06/04/2024 Authors: Ommen SR; Ho CY; Asif IM; Balaji S; Burke MA; Day SM; Dearani JA; Epps KC; Evanovich L; Ferrari VA
  • A cross species thermoelectric and spatiotemporal analysis of alternans in live explanted hearts using dual voltage-calcium fluorescence optical mapping.
    Physiol Meas Volume: 45
    06/04/2024 Authors: Crispino A; Loppini A; Uzelac I; Iravanian S; Bhatia NK; Burke M; Filippi S; Fenton FH; Gizzi A
  • Complex repolarization dynamics in ex vivo human ventricles are independent of the restitution properties.
    Europace Volume: 25
    12/06/2023 Authors: Iravanian S; Uzelac I; Shah AD; Toye MJ; Lloyd MS; Burke MA; Daneshmand MA; Attia TS; Vega JD; El-Chami MF
  • Higher-Order Dynamics Beyond Repolarization Alternans in Ex-Vivo Human Ventricles are Independent of the Restitution Properties.
    medRxiv
    08/21/2023 Authors: Iravanian S; Uzelac I; Shah AD; Toye MJ; Lloyd MS; Burke MA; Daneshmand MA; Attia TS; Vega JD; El-Chami M
  • Quantifying the Eyeball Test: Grip Strength at the Nexus of Frailty, Cachexia and Sarcopenia in Heart Failure.
    J Card Fail Volume: 29 Page(s): 919 - 921
    06/01/2023 Authors: Burke MA
  • Beyond Alternans: Detection of Higher-Order Periodicity in Ex-Vivo Human Ventricles Before Induction of Ventricular Fibrillation.
    bioRxiv
    05/02/2023 Authors: Iravanian S; Uzelac I; Shah AD; Toye MJ; Lloyd MS; Burke MA; Daneshmand MA; Attia TS; Vega JD; Merchant FM
  • An Unusual Clinical Presentation of Danon Disease in a Female
    Volume: 41 Page(s): S344 - S344
    04/01/2022 Authors: Agrawal A; Burke MA; Abdou MH
  • Association of race and gender with primary caregiver relationships and eligibility for advanced heart failure therapies.
    Clin Transplant Volume: 36 Page(s): e14502
    01/01/2022 Authors: Steinberg RS; Nayak A; Burke MA; Aldridge M; Raja Laskar S; Bhatt K; Sridharan L; Abdou M; Attia T; Smith A
  • Growth Differentiation Factor 15 Causes Cardiac Cachexia In Heart Failure
    Volume: 129
    09/03/2021 Authors: Lee DY; Jiao Z; Antolic A; Weiss D; Weitzmann MN; Burke M
  • TGF beta 2-Mediated Cardiac Fibroblast Activation Is Dependent On BET Bromodomain Proteins
    Volume: 129
    09/03/2021 Authors: Antolic A; Jiao Z; Ijaz T; Gupta R; Burke MA
  • 2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
    Volume: 162 Page(s): e23 - e106
    07/01/2021 Authors: Writing Committee Members; Ommen SR; Mital S; Burke MA; Day SM; Deswal A; Elliott P; Evanovich LL; Hung J; Joglar JA
  • BET Protein-Mediated Transcriptional Regulation in Heart Failure.
    Int J Mol Sci Volume: 22
    06/04/2021 Authors: Ijaz T; Burke MA
  • Outflow graft obstruction after left ventricular assist device implantation: a retrospective, single-centre case series.
    ESC Heart Fail Volume: 8 Page(s): 2349 - 2353
    06/01/2021 Authors: Agrawal A; Alexy T; Kamioka N; Shafi T; Stowe J; Morris AA; Vega JD; Babaliaros V; Burke MA
  • 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
    J Am Coll Cardiol Volume: 76 Page(s): 3022 - 3055
    12/22/2020 Authors: Ommen SR; Mital S; Burke MA; Day SM; Deswal A; Elliott P; Evanovich LL; Hung J; Joglar JA; Kantor P
  • 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
    J Am Coll Cardiol Volume: 76 Page(s): e159 - e240
    12/22/2020 Authors: Ommen SR; Mital S; Burke MA; Day SM; Deswal A; Elliott P; Evanovich LL; Hung J; Joglar JA; Kantor P
  • 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
    Circulation Volume: 142 Page(s): e558 - e631
    12/22/2020 Authors: Ommen SR; Mital S; Burke MA; Day SM; Deswal A; Elliott P; Evanovich LL; Hung J; Joglar JA; Kantor P
  • 2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
    Circulation Volume: 142 Page(s): e533 - e557
    12/22/2020 Authors: Ommen SR; Mital S; Burke MA; Day SM; Deswal A; Elliott P; Evanovich LL; Hung J; Joglar JA; Kantor P
  • Outcomes with Impella in Cardiogenic Shock
    Volume: 26 Page(s): S155 - S156
    10/01/2020 Authors: Herve F; Tonleu A; Lyle M; Staloch D; Sridharan L; Bhatt K; Morris A; Burke M; Smith A; Attia T
  • BET bromodomain proteins regulate transcriptional reprogramming in genetic dilated cardiomyopathy.
    JCI Insight Volume: 5
    08/06/2020 Authors: Antolic A; Wakimoto H; Jiao Z; Gorham JM; DePalma SR; Lemieux ME; Conner DA; Lee DY; Qi J; Seidman JG
  • Expanding the clinical and genetic spectrum of ALPK3 variants: Phenotypes identified in pediatric cardiomyopathy patients and adults with heterozygous variants.
    Am Heart J Volume: 225 Page(s): 108 - 119
    07/01/2020 Authors: Herkert JC; Verhagen JMA; Yotti R; Haghighi A; Phelan DG; James PA; Brown NJ; Stutterd C; Macciocca I; Leong K
  • Sex differences in eligibility for advanced heart failure therapies.
    Clin Transplant Volume: 34 Page(s): e13839
    05/01/2020 Authors: Steinberg RS; Nayak A; O'Connell C; Burford S; Pekarek A; Chesnut N; Cole RT; Gupta D; Laskar SR; Bhatt K
  • Outflow Graft Obstruction Causing Recurrent Heart Failure after Left Ventricular Assist Device Implantation.
    Volume: 39 Page(s): S98
    04/01/2020 Authors: Burke MA; Alexy T; Kamioka N; Shafi T; Turbyfield CT; Stowe J; Porter JA; Iturbe JM; Kim DW; Wittersheim KM
  • Validating patient prioritization in the 2018 Revised United Network for Organ Sharing Heart Allocation System: A single-center experience.
    Clin Transplant Volume: 34 Page(s): e13816
    03/01/2020 Authors: Nayak A; Dong T; Ko Y-A; Chesnut N; Pekarek A; Cole RT; Bhatt K; Gupta D; Burke MA; Laskar SR
  • Hypertrophic cardiomyopathy in myosin-binding protein C (MYBPC3) Icelandic founder mutation carriers.
    Open Heart Volume: 7 Page(s): e001220
    01/01/2020 Authors: Adalsteinsdottir B; Burke M; Maron BJ; Danielsen R; Lopez B; Diez J; Jarolim P; Seidman J; Seidman CE; Ho CY
  • Enhanced Left Ventricle TGF[beta]2 Signaling in a Model of Dilated Cardiomyopathy
    Volume: 125
    08/02/2019 Authors: Antolic A; Alsalem AB; Lee DY; Jiao Z; Burke MA
  • Biventricular Impella placement via complete venous access.
    Catheter Cardiovasc Interv Volume: 93 Page(s): E343 - E345
    05/01/2019 Authors: Kamioka N; Patel A; Burke MA; Greenbaum A; Babaliaros V
  • Validating Patient Prioritization in the 2018 Revised UNOS Heart Allocation System: A Single Center Experience
    Volume: 38 Page(s): S133 - S133
    04/01/2019 Authors: Nayak A; Ko Y; Chesnut N; Pekarek A; Cole RT; Bhatt K; Gupta D; Burke M; Laskar SR; Attia TS
  • SEX DIFFERENCES IN ELIGIBILITY FOR ADVANCED HEART FAILURE THERAPIES
    Volume: 73 Page(s): 933 - 933
    03/12/2019 Authors: Steinberg R; Nayak A; Cole R; Gupta D; Laskar S; Bhatt K; Burke M; Smith A; Vega J; Morris AA
  • ELECTROCARDIOGRAPHIC FINDINGS IN MYOSIN- BINDING PROTEIN C FOUNDER MUTATION CARRIERS
    Volume: 73 Page(s): 932 - 932
    03/12/2019 Authors: Adalsteinsdottir B; Burke M; Ho C; Maron B; Danielsen R; Seidman C; Seidman J; Gunnarsson G
  • DIASTOLIC FUNCTION IN MYOSIN-BINDING PROTEIN C FOUNDER MUTATION CARRIERS WITH AND WITHOUT CLINICAL EVIDENCE OF HYPERTROPHIC CARDIOMYOPATHY
    Volume: 73 Page(s): 931 - 931
    03/12/2019 Authors: Adalsteinsdottir B; Ho C; Burke M; Danielsen R; Maron B; Seidman J; Seidman C; Gunnarsson G
  • Unique Cardiac Phenotype in ALPK3-Related Disease: Progression From Dilated Cardiomyopathy to Hypertrophic Cardiomyopathy
    Volume: 138
    11/06/2018 Authors: Herkert JC; Verhagen JM; Phelan DG; James PA; Brown NJ; Stutterd C; Macciocca I; Aggarwal A; Timmer B; Bulthuis ML
  • Epigenomic Control of Cardiac Fibrosis by Bet Bromodomain Proteins in Dilated Cardiomyopathy
    Volume: 24 Page(s): S2 - S2
    08/01/2018 Authors: Burke MA; Wakimoto H; Jiao Z; Gorham JM; DePalma SR; Conner DA; Qi J; Seidman JG; Bradner JE; Brown JD
  • BET Bromodomain Proteins Are Critical Regulators of Molecular Reprogramming in Genetic Dilated Cardiomyopathy
    Volume: 136
    11/14/2017 Authors: Burke MA; Wakimoto H; Gorham JM; DePalma SR; Conner DA; Jiao Z; Qi J; Seidman JG; Bradner JE; Brown JD
  • Corrigendum: Snf1-related kinase improves cardiac mitochondrial efficiency and decreases mitochondrial uncoupling.
    Nat Commun Volume: 8 Page(s): 16155
    08/30/2017 Authors: Rines AK; Chang H-C; Wu R; Sato T; Khechaduri A; Kouzu H; Shapiro J; Shang M; Burke MA; Abdelwahid E
  • Fabry Disease in Families With Hypertrophic Cardiomyopathy: Clinical Manifestations in the Classic and Later-Onset Phenotypes.
    Circ Cardiovasc Genet Volume: 10
    08/01/2017 Authors: Adalsteinsdottir B; Palsson R; Desnick RJ; Gardarsdottir M; Teekakirikul P; Maron M; Appelbaum E; Neisius U; Maron BJ; Burke MA
  • Percutaneous Repair of Continuous Flow Left Ventricular Assist Device (CF-LVAD) Outflow Graft Stenosis: Single Center Experience
    Volume: 23 Page(s): S127 - S127
    08/01/2017 Authors: Alexy T; Kamioka N; Iturbe JM; Vega DJ; Cole RT; Laskar SR; Babaliaros V; Burke MA
  • Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.
    Cell Rep Volume: 19 Page(s): 2410
    06/13/2017 Authors: Hinson JT; Chopra A; Lowe A; Sheng CC; Gupta RM; Kuppusamy R; O'Sullivan J; Rowe G; Wakimoto H; Gorham J
  • Serum NT-probrain natriuretic peptide and high-sensitivity cardiac troponin I levels in carriers of myosin-binding protein C founder mutation
    Volume: 19 Page(s): 82 - 82
    05/01/2017 Authors: Gunnarsson GGT; Adalsteinsdottir B; Ho CY; Maron BJ; Burke MA; Danielsen R; Seidman JG; Seidman CE
  • Snf1-related kinase improves cardiac mitochondrial efficiency and decreases mitochondrial uncoupling.
    Nat Commun Volume: 8 Page(s): 14095
    01/24/2017 Authors: Rines AK; Chang H-C; Wu R; Sato T; Khechaduri A; Kouzu H; Shapiro J; Shang M; Burke MA; Abdelwahid E
  • Clinical and Mechanistic Insights Into theGenetics of Cardiomyopathy.
    J Am Coll Cardiol Volume: 68 Page(s): 2871 - 2886
    12/27/2016 Authors: Burke MA; Cook SA; Seidman JG; Seidman CE
  • Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.
    Cell Rep Volume: 17 Page(s): 3292 - 3304
    12/20/2016 Authors: Hinson JT; Chopra A; Lowe A; Sheng CC; Gupta RM; Kuppusamy R; O'Sullivan J; Rowe G; Wakimoto H; Gorham J
  • Snf1-related Kinase Improves Cardiac Mitochondrial Efficiency by Decreasing Mitochondrial Uncoupling
    Volume: 134
    11/11/2016 Authors: Rines AK; Chang H-C; Wu R; Sato T; Khechaduri A; Shapiro JS; Shang M; Burke MA; Jiang X; Chen C
  • Assessment of diastolic function in carriers of the icelandic myosin-binding protein C founder mutation for hypertrophic cardiomyopathy
    Volume: 37 Page(s): 957 - 957
    08/01/2016 Authors: Adalsteinsdottir B; Ho CY; Maron BJ; Burke MA; Teekakirikul P; Danielsen R; Seidman JG; Seidman CE; Gunnarsson GT
  • BET Bromodomain Inhibition Blunts Heart Failure Progression and Fibrosis in Genetic Cardiomyopathy
    Volume: 119
    07/22/2016 Authors: Burke MA; Wakimoto H; Gorham JM; Conner DA; Seidman JG; Bradner JE; Haldar SM; Brown JD; Seidman CE
  • Corrigendum: Mutation analysis of the phospholamban gene in 315 South Africans with dilated, hypertrophic, peripartum and arrhythmogenic right ventricular cardiomyopathies.
    Sci Rep Volume: 6 Page(s): 25863
    05/18/2016 Authors: Fish M; Shaboodien G; Kraus S; Sliwa K; Seidman CE; Burke MA; Crotti L; Schwartz PJ; Mayosi BM
  • Molecular profiling of dilated cardiomyopathy that progresses to heart failure.
    JCI Insight Volume: 1
    05/05/2016 Authors: Burke MA; Chang S; Wakimoto H; Gorham JM; Conner DA; Christodoulou DC; Parfenov MG; DePalma SR; Eminaga S; Konno T
  • Study of a mouse with proximal titin A-band truncation reveals disease mechanisms and modifiers of titin dilated cardiomyopathy
    Volume: 18 Page(s): 134 - 134
    05/01/2016 Authors: Lunde IG; Wakimoto H; Jiang J; Burke MA; Soukoulis V; Unger A; Christensen G; Linke WA; Seidman JG; Seidman CE
  • Mutation analysis of the phospholamban gene in 315 South Africans with dilated, hypertrophic, peripartum and arrhythmogenic right ventricular cardiomyopathies.
    Sci Rep Volume: 6 Page(s): 22235
    02/26/2016 Authors: Fish M; Shaboodien G; Kraus S; Sliwa K; Seidman CE; Burke MA; Crotti L; Schwartz PJ; Mayosi BM
  • Proximal titin A-band truncation causes dilated cardiomyopathy in response to increased afterload in mice
    Volume: 36 Page(s): 521 - 521
    08/01/2015 Authors: Lunde IG; Wakimoto H; Burke MA; Soukoulis V; Linke WA; Gorham J; Conner D; Christensen G; Seidman JG; Seidman CE
  • Four-and-a-half Lim Domain Protein-1 Upregulation via an Alternate Start Site Prepares the Left Atrium for Birth
    Volume: 117
    07/17/2015 Authors: Salazar IMC; Axelsson A; Wakimoto H; DeLaughter D; Christodoulou D; Jiang J; Burke M; Benson C; Gorham J; Depalma S
  • Titin A-band truncation in mice causes stress-induced dilated cardiomyopathy
    Volume: 17 Page(s): 31 - 31
    05/01/2015 Authors: Lunde IG; Wakimoto H; Burke MA; Soukoulis V; Linke WA; Gorham J; Conner D; Christensen G; Seidman JG; Seidman CE
  • A Non-Invasive Risk Score for the Prediction of Combined Post- and Pre-Capillary Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction
    Volume: 34 Page(s): S118 - S118
    04/01/2015 Authors: Dixon DD; Cogswell R; Burke MA; Cuttica MJ; Freed BH; Beussink-Nelson L; Thenappan T; Shah SJ
  • Phenomapping for novel classification of heart failure with preserved ejection fraction.
    Circulation Volume: 131 Page(s): 269 - 279
    01/20/2015 Authors: Shah SJ; Katz DH; Selvaraj S; Burke MA; Yancy CW; Gheorghiade M; Bonow RO; Huang C-C; Deo RC
  • Inherited Cardiomyopathies
    Page(s): 195 - 218
    01/01/2015 Authors: Burke MA
  • Nationwide study on hypertrophic cardiomyopathy in Iceland: evidence of a MYBPC3 founder mutation.
    Circulation Volume: 130 Page(s): 1158 - 1167
    09/30/2014 Authors: Adalsteinsdottir B; Teekakirikul P; Maron BJ; Burke MA; Gudbjartsson DF; Holm H; Stefansson K; DePalma SR; Mazaika E; McDonough B
  • A Deletion In The N2A Region Of Titin Carried By Muscular Dystrophy With Myositis (mdm) Mice Severely Affects Skeletal Muscle, But Not The Heart
    Volume: 115
    07/18/2014 Authors: Lunde IG; Wakimoto H; Burke MA; Linke W; Christensen G; Seidman JG; Seidman CE
  • Proliferation of Cardiac Fibroblasts Defines Early Stages of Genetic Dilated Cardiomyopathy and Precedes Myocardial Metabolic Derangement
    Volume: 115
    07/18/2014 Authors: Burke MA; Chang S; Christodoulou DC; Gorham JM; Wakimoto H; Seidman CE; Seidman J
  • HYPERTROPHIC CARDIOMYOPATHY IN ICELAND IS CHARACTERIZED BY LOW EVENT RATE CLINICAL COURSE AND MYBPC3 FOUNDER MUTATION
    Volume: 63 Page(s): A827 - A827
    04/01/2014 Authors: Adalsteinsdottir B; Teekakirikul P; Maron B; Gudbjartsson DF; Holm H; Burke M; Danielsen R; Seidman C; Seidman JG; Gunnarsson G
  • UNEXPECTED IDENTIFICATION OF FABRY DISEASE AMONG PATIENTS WITH THE CLINICAL DIAGNOSIS OF HYPERTROPHIC CARDIOMYOPATHY IN ICELAND
    Volume: 63 Page(s): A822 - A822
    04/01/2014 Authors: Adalsteinsdottir B; Teekakirikul P; Maron B; Burke M; Danielsen R; Gardarsdottir M; Palsson R; Desnick R; Seidman C; Seidman JG
  • Assessment and management of heart failure after left ventricular assist device implantation.
    Circulation Volume: 129 Page(s): 1161 - 1166
    03/11/2014 Authors: Burke MA; Givertz MM
  • Prognostic importance of pathophysiologic markers in patients with heart failure and preserved ejection fraction.
    Circ Heart Fail Volume: 7 Page(s): 288 - 299
    03/01/2014 Authors: Burke MA; Katz DH; Beussink L; Selvaraj S; Gupta DK; Fox J; Chakrabarti S; Sauer AJ; Rich JD; Freed BH
  • Association of the frontal QRS-T angle with adverse cardiac remodeling, impaired left and right ventricular function, and worse outcomes in heart failure with preserved ejection fraction.
    J Am Soc Echocardiogr Volume: 27 Page(s): 74 - 82.e2
    01/01/2014 Authors: Selvaraj S; Ilkhanoff L; Burke MA; Freed BH; Lang RM; Martinez EE; Shah SJ
  • Left Atrial Mechanics in Heart Failure With Preserved Ejection Fraction: Prognostic Utility of Left Atrial Strain and Tissue Doppler A' Velocities
    Volume: 128
    11/26/2013 Authors: Freed BH; Aguilar FG; Maganti K; Burke MA; Shah SJ
  • The MAGGIC Risk Score: Validation of a Simple Tool for the Prediction of Morbidity and Mortality in Heart Failure With Preserved Ejection Fraction
    Volume: 128
    11/26/2013 Authors: Rich JD; Klein DA; Saraf SV; Freed BH; Burke MA; Maurer MS; Burkhoff D; Shah SJ
  • Reverse Epidemiology in Heart Failure With Preserved Ejection Fraction: Is the Association Between Total Cholesterol and Worse Outcomes Driven by Right Heart Failure?
    Volume: 128
    11/26/2013 Authors: Vassallo P; Tower-Rader A; Burns JA; Burke MA; Shah SJ
  • Transgenic Overexpression of Snfi-Related Kinase in the Heart Improves Cardiac Metabolic Efficiency Through UCP3 Downregulation and a Reduction in Mitochondrial Uncoupling
    Volume: 128
    11/26/2013 Authors: Rines AK; Khechaduri A; Wu R; Burke MA; Rawlings TA; Wagg CS; Lopaschuk GD; Schumacker PT; Abel ED; Ardehali H
  • Prevalence, clinical characteristics, and outcomes associated with eccentric versus concentric left ventricular hypertrophy in heart failure with preserved ejection fraction.
    Am J Cardiol Volume: 112 Page(s): 1158 - 1164
    10/15/2013 Authors: Katz DH; Beussink L; Sauer AJ; Freed BH; Burke MA; Shah SJ
  • ATP-binding cassette B10 regulates early steps of heme synthesis.
    Circ Res Volume: 113 Page(s): 279 - 287
    07/19/2013 Authors: Bayeva M; Khechaduri A; Wu R; Burke MA; Wasserstrom JA; Singh N; Liesa M; Shirihai OS; Langer NB; Paw BH
  • Association of the Frontal QRS-T Angle with Adverse Cardiac Remodeling, Impaired Biventricular Function, and Worse Outcomes in Heart Failure with Preserved Ejection Fraction
    CIRCULATION Volume: 126
    11/20/2012 Authors: Selvaraj S; Ilkhanoff L; Burke MA; Freed BH; Lang RM; Martinez EE; Shah SJ
  • Phenomapping: Hierarchical Cluster Analysis of Phenotypic Data for the Classification of Heart Failure and Preserved Ejection Fraction
    CIRCULATION Volume: 126
    11/20/2012 Authors: Shah SI; Selvaraj S; Burke MA; Hinchcliff M; Yancy C; Bonow RO; Huang C-C
  • Transgenic Overexpression of Snf1-Related Kinase in the Heart Improves Cardiac Metabolic Efficiency and Resistance to Myocardial Ischemia
    Volume: 126
    11/20/2012 Authors: Rines A; Burke MA; Wu R; Abel ED; Ardehali H
  • Snf1-related kinase inhibits colon cancer cell proliferation through calcyclin-binding protein-dependent reduction of -catenin.
    FASEB J Volume: 26 Page(s): 4685 - 4695
    11/01/2012 Authors: Rines AK; Burke MA; Fernandez RP; Volpert OV; Ardehali H
  • Prevalence, clinical phenotype, and outcomes associated with normal B-type natriuretic peptide levels in heart failure with preserved ejection fraction.
    Am J Cardiol Volume: 110 Page(s): 870 - 876
    09/15/2012 Authors: Anjan VY; Loftus TM; Burke MA; Akhter N; Fonarow GC; Gheorghiade M; Shah SJ
  • Transgenic Overexpression of Snf1-Related Kinase in the Heart Improves Cardiac Metabolic Efficiency and Response to Myocardial Ischemia
    Volume: 111
    08/03/2012 Authors: Rines A; Burke M; Wu R; Abel ED; Ardehali H
  • GLOBAL CHANGES IN THE CELLULAR EPIGENETIC MACHINERY WITH DEVELOPMENT OF LEFT VENTRICULAR HYPERTROPHY
    Volume: 59 Page(s): E965 - E965
    03/27/2012 Authors: Burke MA; Beussink L; Shah S; Joseph J; Wasserstrom JA
  • Targeting myocardial substrate metabolism in heart failure: potential for new therapies.
    Eur J Heart Fail Volume: 14 Page(s): 120 - 129
    02/01/2012 Authors: Ardehali H; Sabbah HN; Burke MA; Sarma S; Liu PP; Cleland JGF; Maggioni A; Fonarow GC; Abel ED; Campia U
  • Snf1-Related Kinase Enhances Cardiomyocyte Metabolism and Increases Mitochondrial Membrane Potential and Glycolysis Through Tribbles Homolog 3 Downregulation
    CIRCULATION Volume: 124
    11/22/2011 Authors: Rines AK; Burke MA; Ardehali H
  • Design, Feasibility, and Clinical Characteristics of a Novel Heart Failure with Preserved Ejection Fraction Program
    Volume: 17 Page(s): S93 - S93
    08/01/2011 Authors: Shah SJ; Burke MA; Gupta D; Anjan V; O'Connell JB; Gheorghiade M; Bonow RO
  • Early clopidogrel use in non-ST elevation acute coronary syndrome and subsequent coronary artery bypass grafting.
    Am Heart J Volume: 161 Page(s): 832 - 841
    05/01/2011 Authors: Burke MA; Lee R; Fintel DJ
  • PATHOPHYSIOLOGIC PREDICTORS OF ADVERSE OUTCOMES IN HEART FAILURE WITH PRESERVED EJECTION FRACTION: IMPORTANCE OF THE RIGHT VENTRICLE
    Volume: 57 Page(s): E399 - E399
    04/05/2011 Authors: Burke MA; Anjan V; Gupta D; Fox J; Chakrabarti S; Shah SJ
  • DETERMINANTS OF ELEVATED PULMONARY VASCULAR RESISTANCE IN HEART FAILURE WITH PRESERVED EJECTION FRACTION
    Volume: 57 Page(s): E400 - E400
    04/05/2011 Authors: Burke MA; Anjan V; Gupta D; Collander B; Shah SJ
  • Platypnea-orthodeoxia syndrome associated with bioprosthetic tricuspid valve stenosis and reverse Lutembacher syndrome.
    Circulation Volume: 123 Page(s): e222 - e224
    02/08/2011 Authors: Burke MA; Mikati IA
  • Snf1-related Kinase (SNRK) Increases Cardiomyocyte Energy and Glycolytic Flux, but Not Aerobic Metabolism, and Reduces Oxidant-induced Cell Death
    CIRCULATION Volume: 122
    11/23/2010 Authors: Rines AK; Burke MA; Nagpal V; Ardehali H
  • Snf1-Related Kinase Is Upregulated by Ischemia and Low Energy and Enhances Energy-Producing Processes
    Volume: 105 Page(s): E20 - E20
    09/25/2009 Authors: Rines A; Burke M; Fernandez R; Prasad SV; Ardehali H
  • Blockade of the erbB2 receptor induces cardiomyocyte death through mitochondrial and reactive oxygen species-dependent pathways.
    J Biol Chem Volume: 284 Page(s): 2080 - 2087
    01/23/2009 Authors: Gordon LI; Burke MA; Singh ATK; Prachand S; Lieberman ED; Sun L; Naik TJ; Prasad SVN; Ardehali H
  • Snf1-related kinase is Upregulated in the Ischemic Heart and Regulates Cellular Metabolism and Death
    Volume: 118 Page(s): S289 - S289
    10/28/2008 Authors: Burke MA; Ochenjele G; Fernandez RP; Ardehali H
  • Snf1-Related Kinase Is Upregulated in the Ischemic Heart and Regulates Cellular Metabolism and Death
    Volume: 103 Page(s): E46 - E46
    08/29/2008 Authors: Burke MA; Ochenjele G; Fernandez RP; Prasad SV; Ardehali H
  • The Mitochondrial ATP-Binding Cassette Protein 2 Is Overexpressed in Ischemic Heart Disease and Regulates Cellular ROS Levels
    Volume: 103 Page(s): E55 - E55
    08/29/2008 Authors: Burke MA; Wu R; Naik T; Prasad SV; Ardehali H
  • The sulfonylurea receptor, an atypical ATP-binding cassette protein, and its regulation of the KATP channel.
    Circ Res Volume: 102 Page(s): 164 - 176
    02/01/2008 Authors: Burke MA; Mutharasan RK; Ardehali H
  • Cytoprotective role of mitochondrial ATP-binding cassette protein-2
    Volume: 116 Page(s): 116 - 117
    10/16/2007 Authors: Wu R; Burke MA; Naik TJ; Prasad SV; Ardehali H
  • ErbB2 blockade and downregulation lead to cardiomyocyte cell death through distinct pathways
    Volume: 101 Page(s): E62 - E62
    08/31/2007 Authors: Gordon LI; Singh A; Prachand S; Lieberman E; Sun L; Burke MA; Naik TJ; Prasad S; Ardehali H
  • Snf1-related kinase (SNRK) is upregulated in ischemic tissue, and its overexpression increases cell death
    Volume: 101 Page(s): E61 - E61
    08/31/2007 Authors: Burke MA; Ardehali H
  • Mitochondrial ATP-binding cassette proteins.
    Transl Res Volume: 150 Page(s): 73 - 80
    08/01/2007 Authors: Burke MA; Ardehali H
  • Interpretation of B-type natriuretic peptide in cardiac disease and other comorbid conditions.
    Heart Fail Rev Volume: 12 Page(s): 23 - 36
    03/01/2007 Authors: Burke MA; Cotts WG
  • Cathepsin L plays an active role in involution of the mouse mammary gland.
    Dev Dyn Volume: 227 Page(s): 315 - 322
    07/01/2003 Authors: Burke MA; Hutter D; Reshamwala RP; Knepper JE
  • Cathepsin L involvement in mouse mammary gland involution
    Volume: 12 Page(s): 416A - 416A
    11/01/2001 Authors: Hutter D; Burke MA; Reshamwala R; Knepper JE
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