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Profile

Larry Tune MD

  • Department of Psychiatry and Behavioral Sciences
    Professor Emeritus
  • (404) 728-4969
  • ltune@emory.edu
Head shot of Larry Tune

Academic Appointment

  • Professor, Department of Neurology, EUSOM
  • Professor, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine (EUSOM)

Education

Degrees

  • No Degree from Cornell Medical Center, New York Hospital
  • MD from University of Virginia
  • Bachelor of Arts, Cum Laude from Cornell University

Research

Publications

  • ELECTROCONVULSIVE THERAPY FOR AKATHISIA: A CASE SERIES AND LITERATURE REVIEW
    Volume: 35 Page(s): E22 - E22
    09/01/2019 Authors: Burke BA; Vazquez M; Janjua AU; Kumari M; Tune L; Hermida AP
  • CATATONIA AND DELIRIUM: KISSING COUSINS OR NO RELATION
    Volume: 26 Page(s): S14 - S14
    03/01/2018 Authors: DeWitt M; Wilson JE; Tune L
  • HOW TO MAKE IT WORK? DIFFERENT MODELS OF GERIATRIC MENTAL HEALTH PRACTICE IN LONG TERM CARE
    Volume: 26 Page(s): S35 - S35
    03/01/2018 Authors: Lu BY; Nash M; Tune L
  • Catatonia Secondary to Olanzapine Discontinuation: A Dramatic Decline and a Dramatic Response
    Volume: 25 Page(s): S109 - S109
    03/01/2017 Authors: Waserstein G; Boazak M; Nagar A; Palanci J; Tune L
  • Treatment of Newly Diagnosed Mild Cognitive Impairment/Early Alzheimer's Disease.
    Focus (Am Psychiatr Publ) Volume: 15 Page(s): 75 - 76
    01/01/2017 Authors: Tune L
  • Perspective: Serum Anticholinergic Drug Level Determinations after 30 Years.
    Am J Geriatr Psychiatry Volume: 24 Page(s): 1189 - 1190
    12/01/2016 Authors: Tune LE
  • SMOKING-HOT ELDER CARE ISSUE: FINE LINE BETWEEN FREEDOM AND SAFETY 2015 CLINICIAN'S DEBATE
    Volume: 23 Page(s): S33 - S34
    03/01/2015 Authors: Patel A; Nash M; Tune L
  • Erratum to "Exploratory analysis of seven Alzheimer's disease genes: disease progression" [Neurobiol. Aging 34 (2013) 1310.e1-1310.e7].
    Neurobiol Aging Volume: 35 Page(s): 2661
    11/01/2014 Authors: Ruiz A; Hernndez I; Ronsende-Roca M; Gonzlez-Prez A; Rodriguez-Noriega E; Ramrez-Lorca R; Maulen A; Moreno-Rey C; Boswell L; Tune L
  • Exploratory analysis of seven Alzheimer's disease genes: disease progression.
    Neurobiol Aging Volume: 34 Page(s): 1310.e1 - 1310.e7
    04/01/2013 Authors: Ruiz A; Hernndez I; Ronsende-Roca M; Gonzlez-Prez A; Rodriguez-Noriega E; Ramrez-Lorca R; Maulen A; Moreno-Rey C; Boswell L; Tune L
  • CLINICIAN'S DEBATE: USE OF PSYCHOTROPIC MEDICATIONS IN THOSE LIVING IN NURSING HOMES WITH A FOCUS ON THOSE WITH DEMENTIA
    Volume: 21 Page(s): S8 - S8
    03/01/2013 Authors: Nash MC; Tune LE; Greenspan D
  • How acute is delirium in nursing homes: an observational study from Wesley Woods at Emory.
    Am J Geriatr Psychiatry Volume: 16 Page(s): 786
    09/01/2008 Authors: Tune LE
  • Nonpharmacological treatment of inappropriate sexual behavior in dementia: the case of the pink panther.
    Am J Geriatr Psychiatry Volume: 16 Page(s): 612 - 613
    07/01/2008 Authors: Tune LE; Rosenberg J
  • Aripiprazole for the treatment of psychoses in institutionalized patients with Alzheimer dementia: a multicenter, randomized, double-blind, placebo-controlled assessment of three fixed doses.
    Am J Geriatr Psychiatry Volume: 15 Page(s): 918 - 931
    11/01/2007 Authors: Mintzer JE; Tune LE; Breder CD; Swanink R; Marcus RN; McQuade RD; Forbes A
  • A retrospective study of the safety of intramuscular ziprasidone in agitated elderly patients.
    J Clin Psychiatry Volume: 66 Page(s): 928 - 929
    07/01/2005 Authors: Greco KE; Tune LE; Brown FW; Van Horn WA
  • Cognitive, behavioral, and physiological changes in Alzheimer disease patients as a function of incontinence medications.
    Am J Geriatr Psychiatry Volume: 13 Page(s): 324 - 328
    04/01/2005 Authors: Jewart RD; Green J; Lu C-J; Cellar J; Tune LE
  • Correlates of anticholinergic activity in patients with dementia and psychosis treated with risperidone or olanzapine.
    J Clin Psychiatry Volume: 65 Page(s): 1708 - 1714
    12/01/2004 Authors: Mulsant BH; Gharabawi GM; Bossie CA; Mao L; Martinez RA; Tune LE; Greenspan AJ; Bastean JN; Pollock BG
  • Schizophrenia in late life.
    Psychiatr Clin North Am Volume: 26 Page(s): 103 - 113
    03/01/2003 Authors: Tune LE; Salzman C
  • Chronic exposure to anticholinergic medications adversely affects the course of Alzheimer's disease
    INTERNATIONAL PSYCHOGERIATRICS Volume: 15 Page(s): 274 - 275
    01/01/2003 Authors: Lu CJ; Tune LE
  • Great progress in diagnosis and treatment of dementia.
    Am J Geriatr Psychiatry Volume: 11 Page(s): 388 - 390
    01/01/2003 Authors: Tune LE
  • Chronic exposure to anticholinergic medications adversely affects the course of Alzheimer disease.
    Am J Geriatr Psychiatry Volume: 11 Page(s): 458 - 461
    01/01/2003 Authors: Lu C-J; Tune LE
  • Dementia management: regulations, rules, and research.
    J Am Med Dir Assoc Volume: 4 Page(s): H13 - H16
    01/01/2003 Authors: Tune LE; Porsteinsson A; Weinberg A
  • Donepezil HCl (E2020) maintains functional brain activity in patients with Alzheimer disease: results of a 24-week, double-blind, placebo-controlled study.
    Am J Geriatr Psychiatry Volume: 11 Page(s): 169 - 177
    01/01/2003 Authors: Tune L; Tiseo PJ; Ieni J; Perdomo C; Pratt RD; Votaw JR; Jewart RD; Hoffman JM
  • Interactive grand rounds: mood stabilizers in dementia.
    Geriatrics Volume: 57 Page(s): suppl 2-5
    09/01/2002 Authors: Nelson JC; Tune LE; Daiello LA; Porsteinsson A
  • Chronic exposure to anticholinergic medications adversely effects the course of Alzheimer's disease
    NEUROBIOLOGY OF AGING Volume: 23 Page(s): S118 - S118
    07/01/2002 Authors: Tune L; Lu CJ
  • The role of antipsychotics in treating delirium.
    Curr Psychiatry Rep Volume: 4 Page(s): 209 - 212
    06/01/2002 Authors: Tune L
  • Interactive grand rounds: Mood stabilizers in dementia.
    AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY Volume: 10 Page(s): 40 - 40
    03/01/2002 Authors: Nelson JC; Tune LE; Daiello L; Porsteinsson AP
  • Receptor binding profile of some medicines reported to have serum anticholinergic activity.
    AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY Volume: 10 Page(s): 95 - 95
    03/01/2002 Authors: Gilmore J; Kennedy JS; Tune LE; Calligaro D; Bymaster F; Felder CC; Verma S
  • Effective treatment of behavioral disturbances in the elderly.
    AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY Volume: 10 Page(s): 40 - 40
    03/01/2002 Authors: Tune LE
  • The muscarinic (hm1-m5) and neuronal-nicotinic receptors binding profile of some medicines reported to have serum anticholinergic activity.
    JOURNAL OF THE AMERICAN GERIATRICS SOCIETY Volume: 49 Page(s): S83 - S84
    04/01/2001 Authors: Kennedy JS; Tune LE; Calligaro D; Bymaster F; Felder CC; Verma S
  • Pharmacologic management of acute delirium: A naturalistic, prospective comparison of atypical antipsychotics and haloperidol.
    JOURNAL OF THE AMERICAN GERIATRICS SOCIETY Volume: 49 Page(s): S93 - S93
    04/01/2001 Authors: Tune L; Jewart R; Egeli S; Greene Y
  • Anticholinergic effects of medication in elderly patients.
    J Clin Psychiatry Volume: 62 Suppl 21 Page(s): 11 - 14
    01/01/2001 Authors: Tune LE
  • Risperidone for the treatment of behavioral and psychological symptoms of dementia.
    J Clin Psychiatry Volume: 62 Suppl 21 Page(s): 29 - 32
    01/01/2001 Authors: Tune LE
  • Assessing psychiatric illness in geriatric patients.
    Clin Cornerstone Volume: 3 Page(s): 23 - 36
    01/01/2001 Authors: Tune L
  • Neuroleptic treatment of late-life schizophrenia.
    Harv Rev Psychiatry Volume: 9 Page(s): 77 - 83
    01/01/2001 Authors: Salzman C; Tune L
  • Serum anticholinergic activity levels and delirium in the elderly.
    Semin Clin Neuropsychiatry Volume: 5 Page(s): 149 - 153
    04/01/2000 Authors: Tune LE
  • Alterations in the functional anatomy of working memory in adult attention deficit hyperactivity disorder.
    Am J Psychiatry Volume: 157 Page(s): 278 - 280
    02/01/2000 Authors: Schweitzer JB; Faber TL; Grafton ST; Tune LE; Hoffman JM; Kilts CD
  • Acetylcholine and delirium.
    Dement Geriatr Cogn Disord Volume: 10 Page(s): 342 - 344
    01/01/1999 Authors: Tune LE; Egeli S
  • The influence of ondansetron and m-chlorophenylpiperazine on scopolamine-induced cognitive, behavioral, and physiological responses in young healthy controls.
    Biol Psychiatry Volume: 43 Page(s): 408 - 416
    03/15/1998 Authors: Broocks A; Little JT; Martin A; Minichiello MD; Dubbert B; Mack C; Tune L; Murphy DL; Sunderland T
  • Depression and Alzheimer's disease.
    Depress Anxiety Volume: 8 Suppl 1 Page(s): 91 - 95
    01/01/1998 Authors: Tune LE
  • New cholinergic therapies: treatment tools for the psychiatrist.
    J Clin Psychiatry Volume: 59 Suppl 13 Page(s): 31 - 35
    01/01/1998 Authors: Tune LE; Sunderland T
  • Diagnosis and treatment of Alzheimer disease and related disorders. Consensus statement of the American Association for Geriatric Psychiatry, the Alzheimer's Association, and the American Geriatrics Society.
    JAMA Volume: 278 Page(s): 1363 - 1371
    10/22/1997 Authors: Small GW; Rabins PV; Barry PP; Buckholtz NS; DeKosky ST; Ferris SH; Finkel SI; Gwyther LP; Khachaturian ZS; Lebowitz BD
  • Multiple lines of evidence for dopamine dysfunction in psychosis by imaging
    SCHIZOPHRENIA RESEARCH Volume: 24 Page(s): 183 - 183
    03/01/1997 Authors: Wong DF; Gjedde A; Reith J; Grunder G; Szymanski S; Yokoi F; Hong C; Nestadt G; Neufeld K; Pearlson G
  • Quantification of neuroreceptors in the living human brain: IV. Effect of aging and elevations of D2-like receptors in schizophrenia and bipolar illness.
    J Cereb Blood Flow Metab Volume: 17 Page(s): 331 - 342
    03/01/1997 Authors: Wong DF; Pearlson GD; Tune LE; Young LT; Meltzer CC; Dannals RF; Ravert HT; Reith J; Kuhar MJ; Gjedde A
  • Quantitative MRI volume changes in late onset schizophrenia and Alzheimer's disease compared to normal controls.
    Psychiatry Res Volume: 68 Page(s): 65 - 75
    02/07/1997 Authors: Barta PE; Powers RE; Aylward EH; Chase GA; Harris GJ; Rabins PV; Tune LE; Pearlson GD
  • Lack of relationship of neuroleptic dose and blood serum levels to neuropsychological performance on the LNNB in chronic schizophrenia.
    Int J Neurosci Volume: 87 Page(s): 107 - 110
    10/01/1996 Authors: Puente AE; Tune L
  • Regional hypometabolism in Alzheimer's disease as measured by positron emission tomography after correction for effects of partial volume averaging.
    Neurology Volume: 47 Page(s): 454 - 461
    08/01/1996 Authors: Meltzer CC; Zubieta JK; Brandt J; Tune LE; Mayberg HS; Frost JJ
  • Striatal dopamine D2 receptor quantification and superior temporal gyrus: volume determination in 14 chronic schizophrenic subjects.
    Psychiatry Res Volume: 67 Page(s): 155 - 158
    07/31/1996 Authors: Tune L; Barta P; Wong D; Powers RE; Pearlson G; Tien AY; Wagner HN
  • Temporal lobe changes distinguish schizophrenia from bipolar disorder
    BIOLOGICAL PSYCHIATRY Volume: 39 Page(s): 471 - 471
    04/01/1996 Authors: Pearlson G; Barta P; Tune L; Tien A; Chase G
  • Major depression in Alzheimer's disease. An interaction between gender and family history.
    Psychosomatics Volume: 37 Page(s): 380 - 384
    01/01/1996 Authors: Lyketsos CG; Tune LE; Pearlson G; Steele C
  • Serotonergic modulation of anticholinergic effects on cognition and behavior in elderly humans.
    Psychopharmacology (Berl) Volume: 120 Page(s): 280 - 288
    08/01/1995 Authors: Little JT; Broocks A; Martin A; Hill JL; Tune LE; Mack C; Cantillon M; Molchan S; Murphy DL; Sunderland T
  • In vivo D2 dopamine receptor density in psychotic and nonpsychotic patients with bipolar disorder.
    Arch Gen Psychiatry Volume: 52 Page(s): 471 - 477
    06/01/1995 Authors: Pearlson GD; Wong DF; Tune LE; Ross CA; Chase GA; Links JM; Dannals RF; Wilson AA; Ravert HT; Wagner HN
  • Changes in visual fixation and saccadic eye movements in Alzheimer's disease.
    Int J Psychophysiol Volume: 19 Page(s): 33 - 40
    02/01/1995 Authors: Bylsma FW; Rasmusson DX; Rebok GW; Keyl PM; Tune L; Brandt J
  • "Cholinergic score" and delirium.
    J Neuropsychiatry Clin Neurosci Volume: 6 Page(s): 65 - 66
    01/01/1994 Authors: Maas HA; Wils V
  • The effects of Alzheimer disease on driving-related abilities.
    Alzheimer Dis Assoc Disord Volume: 8 Page(s): 228 - 240
    01/01/1994 Authors: Rebok GW; Keyl PM; Bylsma FW; Blaustein MJ; Tune L
  • Dopamine D2 receptor density estimates in schizophrenia: a positron emission tomography study with 11C-N-methylspiperone.
    Psychiatry Res Volume: 49 Page(s): 219 - 237
    12/01/1993 Authors: Tune LE; Wong DF; Pearlson G; Strauss M; Young T; Shaya EK; Dannals RF; Wilson AA; Ravert HT; Sapp J
  • Anticholinergic effects of drugs for the elderly.
    Am J Psychiatry Volume: 150 Page(s): 1756 - 1757
    11/01/1993 Authors: Ball C
  • ANTICHOLINERGIC EFFECTS OF DRUGS FOR THE ELDERLY - REPLY
    AMERICAN JOURNAL OF PSYCHIATRY Volume: 150 Page(s): 1757 - 1757
    11/01/1993 Authors: TUNE LE
  • QUANTITATION OF REGIONAL GLUCOSE METABOLIC-ACTIVITY IN ALZHEIMER-DISEASE AFTER CORRECTION FOR EFFECTS OF ATROPHY
    JOURNAL OF NUCLEAR MEDICINE Volume: 34 Page(s): P5 - P5
    05/01/1993 Authors: MELTZER CC; BRANDT J; TUNE LE; MAYBERG HS; MUELLERGARTNER HW; FROST JJ
  • Association of anticholinergic activity of prescribed medications with postoperative delirium.
    J Neuropsychiatry Clin Neurosci Volume: 5 Page(s): 208 - 210
    01/01/1993 Authors: Tune L; Carr S; Cooper T; Klug B; Golinger RC
  • Quantitative D2 dopamine receptor PET and structural MRI changes in late-onset schizophrenia.
    Schizophr Bull Volume: 19 Page(s): 783 - 795
    01/01/1993 Authors: Pearlson GD; Tune LE; Wong DF; Aylward EH; Barta PE; Powers RE; Tien AY; Chase GA; Harris GJ; Rabins PV
  • Anticholinergic effects of drugs commonly prescribed for the elderly: potential means for assessing risk of delirium.
    Am J Psychiatry Volume: 149 Page(s): 1393 - 1394
    10/01/1992 Authors: Tune L; Carr S; Hoag E; Cooper T
  • Sylvian fissure size in schizophrenia measured with the magnetic resonance imaging rating protocol of the Consortium to Establish a Registry for Alzheimer's Disease.
    Am J Psychiatry Volume: 149 Page(s): 1195 - 1198
    09/01/1992 Authors: Schwartz JM; Aylward E; Barta PE; Tune LE; Pearlson GD
  • Quantitative changes in mesial temporal volume, regional cerebral blood flow, and cognition in Alzheimer's disease.
    Arch Gen Psychiatry Volume: 49 Page(s): 402 - 408
    05/01/1992 Authors: Pearlson GD; Harris GJ; Powers RE; Barta PE; Camargo EE; Chase GA; Noga JT; Tune LE
  • THE RELATIONSHIP OF PET D2 DOPAMINE RECEPTOR FINDINGS TO SUPERIOR TEMPORAL GYRAL VOLUME ESTIMATES IN 14 SCHIZOPHRENIC SUBJECTS
    SCHIZOPHRENIA RESEARCH Volume: 6 Page(s): 147 - 148
    01/01/1992 Authors: TUNE LE; PEARLSON GD; BARTA PE; POWERS RE; WONG DF
  • INVIVO DOPAMINE D2 RECEPTOR DENSITY IN PSYCHOTIC AND NONPSYCHOTIC BIPOLAR PATIENTS
    SCHIZOPHRENIA RESEARCH Volume: 6 Page(s): 147 - 147
    01/01/1992 Authors: PEARLSON GD; WONG DF; TUNE LE
  • ELEVATED DOPAMINE 2 RECEPTOR DENSITY IN 23 SCHIZOPHRENIC-PATIENTS - A POSITRON EMISSION TOMOGRAPHY STUDY WITH [C-11] N-METHYLSPIPERONE
    SCHIZOPHRENIA RESEARCH Volume: 6 Page(s): 147 - 147
    01/01/1992 Authors: TUNE LE; WONG DF; PEARLSON GD
  • Anticholinergic delirium caused by topical homatropine ophthalmologic solution: confirmation by anticholinergic radioreceptor assay in two cases.
    J Neuropsychiatry Clin Neurosci Volume: 4 Page(s): 195 - 197
    01/01/1992 Authors: Tune LE; Bylsma FW; Hilt DC
  • Neuroleptic drugs in the management of behavioral symptoms of Alzheimer's disease.
    Psychiatr Clin North Am Volume: 14 Page(s): 353 - 373
    06/01/1991 Authors: Tune LE; Steele C; Cooper T
  • MRI AND PET STUDIES IN LATE LIFE-ONSET SCHIZOPHRENICS
    SCHIZOPHRENIA RESEARCH Volume: 4 Page(s): 409 - 410
    05/01/1991 Authors: PEARLSON GD; TUNE LE; POWERS RE; WONG DF; RABINS PV; BARTA PE
  • MESIAL TEMPORAL VOLUME CHANGES ON MRI IN SCHIZOPHRENIC AND AFFECTIVE PATIENTS
    SCHIZOPHRENIA RESEARCH Volume: 4 Page(s): 409 - 409
    05/01/1991 Authors: PEARLSON GD; POWERS RE; BARTA PE; AYLWARD EH; TUNE LE
  • Postoperative delirium.
    Int Psychogeriatr Volume: 3 Page(s): 325 - 332
    01/01/1991 Authors: Tune LE
  • Benzodiazepine-induced and anticholinergic-induced delirium in the elderly.
    Int Psychogeriatr Volume: 3 Page(s): 397 - 408
    01/01/1991 Authors: Tune LE; Bylsma FW
  • Physostigmine in Alzheimer's disease: effects on cognitive functioning, cerebral glucose metabolism analyzed by positron emission tomography and cerebral blood flow analyzed by single photon emission tomography.
    Volume: 366 Page(s): 61 - 65
    01/01/1991 Authors: Tune L; Brandt J; Frost JJ; Harris G; Mayberg H; Steele C; Burns A; Sapp J; Folstein MF; Wagner HN
  • Auditory hallucinations and smaller superior temporal gyral volume in schizophrenia.
    Am J Psychiatry Volume: 147 Page(s): 1457 - 1462
    11/01/1990 Authors: Barta PE; Pearlson GD; Powers RE; Richards SS; Tune LE
  • Polymerase chain reaction: powerful tool coming of age.
    J Natl Cancer Inst Volume: 82 Page(s): 1093 - 1094
    07/04/1990 Authors: Tune L
  • D2 receptors in Huntington's disease: positron emission tomography findings and clinical correlates.
    J Neuropsychiatry Clin Neurosci Volume: 2 Page(s): 20 - 27
    01/01/1990 Authors: Brandt J; Folstein SE; Wong DF; Links J; Dannals RF; McDonnell-Sill A; Starkstein S; Anders P; Strauss ME; Tune LE
  • Effects of anticholinergic medication on memory in schizophrenia.
    Schizophr Res Volume: 3 Page(s): 127 - 129
    01/01/1990 Authors: Strauss ME; Reynolds KS; Jayaram G; Tune LE
  • Alzheimer's dementia: performance on parallel forms of the dementia assessment battery.
    J Clin Exp Neuropsychol Volume: 11 Page(s): 899 - 912
    09/01/1989 Authors: Teng EL; Wimer C; Roberts E; Damasio AR; Eslinger PJ; Folstein MF; Tune LE; Whitehouse PJ; Bardolph EL; Chui HC
  • A chart review study of late-onset and early-onset schizophrenia.
    Am J Psychiatry Volume: 146 Page(s): 1568 - 1574
    12/01/1989 Authors: Pearlson GD; Kreger L; Rabins PV; Chase GA; Cohen B; Wirth JB; Schlaepfer TB; Tune LE
  • Ventricle-brain ratio, computed tomographic density, and brain area in 50 schizophrenics.
    Arch Gen Psychiatry Volume: 46 Page(s): 690 - 697
    08/01/1989 Authors: Pearlson GD; Kim WS; Kubos KL; Moberg PJ; Jayaram G; Bascom MJ; Chase GA; Goldfinger AD; Tune LE
  • Multicenter trial of naloxone in Alzheimer's disease.
    Ann Neurol Volume: 25 Page(s): 404 - 406
    04/01/1989 Authors: Henderson VW; Roberts E; Wimer C; Bardolph EL; Chui HC; Damasio AR; Eslinger PJ; Folstein MF; Schneider LS; Teng EL
  • Driving in patients with dementia.
    J Am Geriatr Soc Volume: 36 Page(s): 1087 - 1091
    12/01/1988 Authors: Lucas-Blaustein MJ; Filipp L; Dungan C; Tune L
  • Response to drugs in schizophrenia: the influence of family history, obstetric complications and ventricular enlargement.
    Psychol Med Volume: 18 Page(s): 583 - 592
    08/01/1988 Authors: Nimgaonkar VL; Wessely S; Tune LE; Murray RM
  • D2-DOPAMINE RECEPTORS IN TOURETTES SYNDROME AND MANIC-DEPRESSIVE ILLNESS
    CLINICAL NUCLEAR MEDICINE Volume: 13 Page(s): 392 - 392
    05/01/1988 Authors: WONG DF; SINGER H; PEARLSON G; TUNE L; ROSS C; VILLEMAGNE V; DANNALS RF; LINKS JM; WILSON A; RAVERT H
  • In reply: elevated d2 dopamine receptors in drug-naive schizophrenics.
    Science Volume: 239 Page(s): 790 - 791
    02/12/1988 Authors: Wong DF; Gjedde A; Wagner HM; Dannals RF; Links JM; Tune LE; Pearlson GD
  • Workshop on schizophrenia, PET, and dopamine D2 receptors in the human neostriatum.
    Schizophr Bull Volume: 14 Page(s): 471 - 484
    01/01/1988 Authors: Andreasen NC; Carson R; Diksic M; Evans A; Farde L; Gjedde A; Hakim A; Lal S; Nair N; Sedvall G
  • Self-care capacity and anticholinergic drug levels in nursing home patients.
    Am J Psychiatry Volume: 145 Page(s): 107 - 109
    01/01/1988 Authors: Rovner BW; David A; Lucas-Blaustein MJ; Conklin B; Filipp L; Tune L
  • Positron emission tomography imaging of dopamine and serotonin receptors in Huntington's chorea.
    Am J Physiol Imaging Volume: 3 Page(s): 51
    01/01/1988 Authors: Wong DF; Wagner HN; Links JM; Dannals RF; Folstein S; Ravert HT; Tune L; Pearlson G; Frost JJ; Folstein M
  • Association of elevated plasma anticholinergic activity with delirium in surgical patients.
    Am J Psychiatry Volume: 144 Page(s): 1218 - 1220
    09/01/1987 Authors: Golinger RC; Peet T; Tune LE
  • Increased ventricle-to-brain ratio in late-onset schizophrenia.
    Am J Psychiatry Volume: 144 Page(s): 1216 - 1218
    09/01/1987 Authors: Rabins P; Pearlson G; Jayaram G; Steele C; Tune L
  • Amoxapine-induced cognitive impairment in two patients.
    J Clin Psychiatry Volume: 48 Page(s): 166 - 167
    04/01/1987 Authors: Burns A; Tune L
  • CEREBRAL VBRS AND CSF ACHE ACTIVITY IN SENILE DEMENTIA
    INTERNATIONAL JOURNAL OF NEUROSCIENCE Volume: 32 Page(s): 520 - 520
    01/01/1987 Authors: TUNE LE; PEARLSON GD
  • C-11 N-METHYL SPIPERONE PET SCANS IN PSYCHIATRIC-DISORDERS
    INTERNATIONAL JOURNAL OF NEUROSCIENCE Volume: 32 Page(s): 329 - 329
    01/01/1987 Authors: TUNE L; PEARLSON G; WONG D; WAGNER H
  • RELAPSE IN CHRONIC-SCHIZOPHRENICS TREATED WITH FLUPHENAZINE DECANOATE ASSOCIATED WITH LOW SERUM NEUROLEPTIC LEVELS
    INTERNATIONAL JOURNAL OF NEUROSCIENCE Volume: 32 Page(s): 685 - 685
    01/01/1987 Authors: JAYARAM G; COYLE J; TUNE L
  • Span of apprehension deficits in schizophrenia and mania.
    Schizophr Bull Volume: 13 Page(s): 699 - 704
    01/01/1987 Authors: Strauss ME; Prescott CA; Gutterman DF; Tune LE
  • CORRELATES OF ATTENTION IN SCHIZOPHRENIA
    INTERNATIONAL JOURNAL OF NEUROSCIENCE Volume: 32 Page(s): 680 - 680
    01/01/1987 Authors: STRAUSS M; LEU MF; COYLE JT; TUNE LE
  • Positron emission tomography reveals elevated D2 dopamine receptors in drug-naive schizophrenics.
    Science Volume: 234 Page(s): 1558 - 1563
    12/19/1986 Authors: Wong DF; Wagner HN; Tune LE; Dannals RF; Pearlson GD; Links JM; Tamminga CA; Broussolle EP; Ravert HT; Wilson AA
  • INVIVO QUANTIFICATION OF ABSOLUTE D2 DOPAMINE RECEPTOR DENSITY USING POSITRON EMISSION TOMOGRAPHY - PRELIMINARY HUMAN STUDIES
    JOURNAL OF NUCLEAR MEDICINE Volume: 27 Page(s): 954 - 955
    06/01/1986 Authors: WONG DF; GJEDDE A; WAGNER HN; DANNALS RF; TUNE L; TAMMINGA C; OTUAMA L; WILLIAMS J; GOLDBERG DS; LINKS J
  • Haloperidol versus thioridazine in the treatment of behavioral symptoms in senile dementia of the Alzheimer's type: preliminary findings.
    J Clin Psychiatry Volume: 47 Page(s): 310 - 312
    06/01/1986 Authors: Steele C; Lucas MJ; Tune L
  • Relapse in chronic schizophrenics treated with fluphenazine decanoate is associated with low serum neuroleptic levels.
    J Clin Psychiatry Volume: 47 Page(s): 247 - 248
    05/01/1986 Authors: Jayaram G; Coyle J; Tune L
  • Test-retest reliability of information-processing measures among chronic schizophrenics.
    Psychiatry Res Volume: 17 Page(s): 199 - 202
    03/01/1986 Authors: Prescott CA; Strauss ME; Tune LE
  • Post-operative delirium.
    Adv Psychosom Med Volume: 15 Page(s): 51 - 68
    01/01/1986 Authors: Tune L; Folstein MF
  • Cerebral ventricular size and cerebrospinal fluid acetylcholinesterase levels in senile dementia of the Alzheimer type.
    Psychiatry Res Volume: 17 Page(s): 23 - 29
    01/01/1986 Authors: Pearlson GD; Tune LE
  • Serum neuroleptic levels and extrapyramidal side effects in patients treated with amoxapine.
    J Clin Psychiatry Volume: 46 Page(s): 428 - 429
    10/01/1985 Authors: Gaffney GR; Tune LE
  • Psychopharmacologic and clinical correlates of attention in chronic schizophrenia.
    Am J Psychiatry Volume: 142 Page(s): 497 - 499
    04/01/1985 Authors: Strauss ME; Lew MF; Coyle JT; Tune LE
  • Cerebrospinal fluid acetylcholinesterase activity in senile dementia of the Alzheimer type.
    Ann Neurol Volume: 17 Page(s): 46 - 48
    01/01/1985 Authors: Tune L; Gucker S; Folstein M; Oshida L; Coyle JT
  • ASSESSMENT OF DOPAMINE RECEPTOR BLOCKADE BY NEUROLEPTIC DRUGS IN THE LIVING HUMAN-BRAIN
    JOURNAL OF NUCLEAR MEDICINE Volume: 26 Page(s): P52 - P53
    01/01/1985 Authors: WONG DF; WAGNER HN; COYLE J; SNYDER S; DANNALS R; LAFRANCE N; BICE A; PEARLSON G; LINKS J; PAULOS M
  • DOPAMINE AND SEROTONIN RECEPTORS MEASURED INVIVO IN HUNTINGTONS-DISEASE WITH C-11 N-METHYLSPIPERONE PET IMAGING
    JOURNAL OF NUCLEAR MEDICINE Volume: 26 Page(s): P107 - P107
    01/01/1985 Authors: WONG DF; LINKS JM; WAGNER HN; FOLSTEIN SE; SUNEJA S; DANNALS RF; RAVERT HT; WILSON AA; TUNE LE; PEARLSON G
  • THE RELATIONSHIP BETWEEN LNNB SCALE SCORES AND NEUROLEPTIC DOSAGE LEVELS IN SCHIZOPHRENICS
    INTERNATIONAL JOURNAL OF CLINICAL NEUROPSYCHOLOGY Volume: 7 Page(s): 69 - 69
    01/01/1985 Authors: PUENTE AE; TUNE L; ORRELL T; HENDRICKSON J
  • BENEFITS OF CORRELATING NEUROLEPTIC BLOOD LEVEL AND AUDITORY DISTRACTIBILITY - REPLY
    AMERICAN JOURNAL OF PSYCHIATRY Volume: 142 Page(s): 1523 - 1524
    01/01/1985 Authors: STRAUSS ME; TUNE LE
  • INVIVO ASSESSMENT OF DOPAMINE AND SEROTONIN RECEPTORS MEASURED BY C-11 N-METHYLSPIPERONE (NMSP) IN PATIENTS WITH SCHIZOPHRENIA
    JOURNAL OF NUCLEAR MEDICINE Volume: 26 Page(s): P107 - P107
    01/01/1985 Authors: WONG DF; TUNE LE; WAGNER HN; SUNEJA S; BJORVINSSON E; PEARLSON G; DANNALS RF; RAVERT HT; WILSON AA; LINKS JM
  • INVIVO ASSESSMENT OF DOPAMINE D-2 AND SEROTONIN S-2 RECEPTORS MEASURED BY C-11 N-METHYLSPIPERONE (NMSP) IN MANIC-DEPRESSIVE ILLNESS
    JOURNAL OF NUCLEAR MEDICINE Volume: 26 Page(s): P107 - P107
    01/01/1985 Authors: WONG DF; PEARLSON G; WAGNER HN; DANNALS RF; SUNEJA S; BJORGVINSSON E; LINKS JM; RAVERT HT; WILSON AA; SCHAERF F
  • Dopamine receptor binding of C-11-3-N-methylspiperone in the caudate in schizophrenia and bipolar disorder: a preliminary report.
    Psychopharmacol Bull Volume: 21 Page(s): 595 - 598
    01/01/1985 Authors: Wong DF; Wagner HN; Pearlson G; Dannals RF; Links JM; Ravert HT; Wilson AA; Suneja S; Bjorvvinssen E; Kuhar MJ
  • Serum neuroleptic concentrations and clinical response: a radioreceptor assay investigation of acutely psychotic patients.
    Psychopharmacology (Berl) Volume: 82 Page(s): 194 - 198
    01/01/1984 Authors: Kucharski LT; Alexander P; Tune L; Coyle J
  • Post-ECT confusional states associated with elevated serum anticholinergic levels.
    Am J Psychiatry Volume: 140 Page(s): 930 - 931
    07/01/1983 Authors: Mondimore FM; Damlouji N; Folstein MF; Tune L
  • CORRECTION
    AMERICAN JOURNAL OF PSYCHIATRY Volume: 140 Page(s): 824 - 824
    01/01/1983 Authors: TUNE LE
  • An approach to the management of dementia syndromes.
    Johns Hopkins Med J Volume: 151 Page(s): 362 - 368
    12/01/1982 Authors: Steele C; Lucas MJ; Tune LE
  • Serum levels of anticholinergic drugs and impaired recent memory in chronic schizophrenic patients.
    Am J Psychiatry Volume: 139 Page(s): 1460 - 1462
    11/01/1982 Authors: Tune LE; Strauss ME; Lew MF; Breitlinger E; Coyle JT
  • Dopaminergic dsyfunction in Tourette syndrome.
    Ann Neurol Volume: 12 Page(s): 361 - 366
    10/01/1982 Authors: Singer HS; Butler IJ; Tune LE; Seifert WE; Coyle JT
  • Familial manic-depressive illness and familial Parkinson's disease: a case report.
    Johns Hopkins Med J Volume: 151 Page(s): 65 - 70
    08/01/1982 Authors: Tune LE; Folstein M; Rabins P; Jayaram G; McHugh P
  • Drug management in chronic schizophrenia.
    Johns Hopkins Med J Volume: 150 Page(s): 45 - 48
    01/01/1982 Authors: Tune LE; McHugh PR; Coyle JT
  • Neuroleptic serum levels in mentally retarded boys.
    Psychopharmacol Bull Volume: 18 Page(s): 65 - 66
    01/01/1982 Authors: Harris JC; Tune LE; Kurtz M; Coyle JT
  • Clinical symptomatology, CSF neurotransmitter metabolites, and serum haloperidol levels in Tourette syndrome.
    Adv Neurol Volume: 35 Page(s): 177 - 183
    01/01/1982 Authors: Singer HS; Tune LE; Butler IJ; Zaczek R; Coyle JT
  • Neuroleptic drug level monitoring in psychiatry: focus on radioreceptor assay techniques.
    Ther Drug Monit Volume: 4 Page(s): 59 - 64
    01/01/1982 Authors: Tune LE; Coyle JT
  • Association of postoperative delirium with raised serum levels of anticholinergic drugs.
    Lancet Volume: 2 Page(s): 651 - 653
    09/26/1981 Authors: Tune LE; Damlouji NF; Holland A; Gardner TJ; Folstein MF; Coyle JT
  • Management of akathisia in a severely retarded adolescent male with help of an anticholinergic drug assay.
    Lancet Volume: 2 Page(s): 414
    08/22/1981 Authors: Harris JC; Tune LE; Allen M; Coyle JT
  • Tardive dyskinesia.
    Johns Hopkins Med J Volume: 148 Page(s): 206 - 211
    05/01/1981 Authors: Rabins PV; Tune LE; McHugh PR
  • Management of extrapyramidal side effects induced by neuroleptics.
    Johns Hopkins Med J Volume: 148 Page(s): 149 - 153
    03/01/1981 Authors: Tune LE; McHugh PR; Coyle JT
  • Acute extrapyramidal side effects: serum levels of neuroleptics and anticholinergics.
    Psychopharmacology (Berl) Volume: 75 Page(s): 9 - 15
    01/01/1981 Authors: Tune L; Coyle JT
  • CLINICAL SYMPTOMATOLOGY, CEREBROSPINAL-FLUID NEUROTRANSMITTER METABOLITES, AND SERUM HALOPERIDOL LEVELS IN TOURETTE SYNDROME
    ANNALS OF NEUROLOGY Volume: 10 Page(s): 303 - 303
    01/01/1981 Authors: SINGER H; TUNE L; BUTLER I; ZACZEK R; COYLE J
  • Serum haloperidol levels in Gilles de la Tourette syndrome.
    Biol Psychiatry Volume: 16 Page(s): 79 - 84
    01/01/1981 Authors: Singer HS; Rabins P; Tune LE; Coyle JT
  • Neuroleptic serum levels measured by radioreceptor assay and clinical response in schizophrenic patients.
    J Nerv Ment Dis Volume: 169 Page(s): 60 - 63
    01/01/1981 Authors: Tune LE; Creese I; DePaulo JR; Slavney PR; Snyder SH
  • Clinical response and serum neuroleptic levels in childhood schizophrenia.
    Am J Psychiatry Volume: 137 Page(s): 483 - 484
    04/01/1980 Authors: Meyers B; Tune LE; Coyle JT
  • Serum levels of anticholinergic drugs in treatment of acute extrapyramidal side effects.
    Arch Gen Psychiatry Volume: 37 Page(s): 293 - 297
    03/01/1980 Authors: Tune L; Coyle JT
  • Clinical state and serum neuroleptic levels measured by radioreceptor assay in schizophrenia.
    Am J Psychiatry Volume: 137 Page(s): 187 - 190
    02/01/1980 Authors: Tune LE; Creese I; Depaulo JR; Slavney PR; Coyle JT; Snyder SH
  • Low neuroleptic serum levels in patients receiving fluphenazine decanoate.
    Am J Psychiatry Volume: 137 Page(s): 80 - 82
    01/01/1980 Authors: Tune LE; Creese I; Coyle JT; Pearlson G; Snyder SH
  • Tricyclic antidepressant radioreceptor assay.
    Eur J Pharmacol Volume: 58 Page(s): 473 - 477
    10/15/1979 Authors: Innis RB; Tune L; Rock R; Depaulo R; U'Prichard DC; Snyder SH
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