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Profile

Lingyan Ping

  • Department of Neurology
    Senior Associate
  • lingyan.ping@emory.edu

Research

Publications

  • Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease.
    Nat Med Volume: 29 Page(s): 1979 - 1988
    08/01/2023 Authors: Johnson ECB; Bian S; Haque RU; Carter EK; Watson CM; Gordon BA; Ping L; Duong DM; Epstein MP; McDade E
  • Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer's disease.
    Mol Neurodegener Volume: 18 Page(s): 48
    07/19/2023 Authors: Modeste ES; Ping L; Watson CM; Duong DM; Dammer EB; Johnson ECB; Roberts BR; Lah JJ; Levey AI; Seyfried NT
  • Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease.
    Sci Data Volume: 10 Page(s): 261
    05/09/2023 Authors: Watson CM; Dammer EB; Ping L; Duong DM; Modeste E; Carter EK; Johnson ECB; Levey AI; Lah JJ; Roberts BR
  • Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
    bioRxiv
    01/23/2023 Authors: Seddighi S; Qi YA; Brown A-L; Wilkins OG; Bereda C; Belair C; Zhang Y; Prudencio M; Keuss MJ; Khandeshi A
  • Multi-platform proteomic analysis of Alzheimer's disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome.
    Alzheimers Res Ther Volume: 14 Page(s): 174
    11/17/2022 Authors: Dammer EB; Ping L; Duong DM; Modeste ES; Seyfried NT; Lah JJ; Levey AI; Johnson ECB
  • Interrogating the Metabolomic Profile of Amyotrophic Lateral Sclerosis in the Post-Mortem Human Brain by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI) Mass Spectrometry Imaging (MSI).
    Metabolites Volume: 12
    11/10/2022 Authors: Sohn AL; Ping L; Glass JD; Seyfried NT; Hector EC; Muddiman DC
  • Signatures of glial activity can be detected in the CSF proteome.
    Proc Natl Acad Sci U S A Volume: 119 Page(s): e2119804119
    06/14/2022 Authors: Eninger T; Mller SA; Bacioglu M; Schweighauser M; Lambert M; Maia LF; Neher JJ; Hornfeck SM; Obermller U; Kleinberger G
  • Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level.
    Nat Neurosci Volume: 25 Page(s): 213 - 225
    02/01/2022 Authors: Johnson ECB; Carter EK; Dammer EB; Duong DM; Gerasimov ES; Liu Y; Liu J; Betarbet R; Ping L; Yin L
  • Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization.
    J Biol Chem Volume: 297 Page(s): 101306
    11/01/2021 Authors: Kundinger SR; Dammer EB; Yin L; Hurst C; Shapley S; Ping L; Khoshnevis S; Ghalei H; Duong DM; Seyfried NT
  • Extracellular signal-regulated kinase regulates microglial immune responses in Alzheimer's disease.
    J Neurosci Res Volume: 99 Page(s): 1704 - 1721
    06/01/2021 Authors: Chen MJ; Ramesha S; Weinstock LD; Gao T; Ping L; Xiao H; Dammer EB; Duong DD; Levey AI; Lah JJ
  • Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease.
    Sci Adv Volume: 6
    10/01/2020 Authors: Higginbotham L; Ping L; Dammer EB; Duong DM; Zhou M; Gearing M; Hurst C; Glass JD; Factor SA; Johnson ECB
  • Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease.
    Sci Data Volume: 7 Page(s): 315
    09/28/2020 Authors: Ping L; Kundinger SR; Duong DM; Yin L; Gearing M; Lah JJ; Levey AI; Seyfried NT
  • Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.
    Nat Med Volume: 26 Page(s): 769 - 780
    05/01/2020 Authors: Johnson ECB; Dammer EB; Duong DM; Ping L; Zhou M; Yin L; Higginbotham LA; Guajardo A; White B; Troncoso JC
  • Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer's disease.
    Clin Proteomics Volume: 17 Page(s): 19
    01/01/2020 Authors: Zhou M; Haque RU; Dammer EB; Duong DM; Ping L; Johnson ECB; Lah JJ; Levey AI; Seyfried NT
  • Proteomics Links Ubiquitin Chain Topology Change to Transcription Factor Activation.
    Mol Cell Volume: 76 Page(s): 126 - 137.e7
    10/03/2019 Authors: Li Y; Dammer EB; Gao Y; Lan Q; Villamil MA; Duong DM; Zhang C; Ping L; Lauinger L; Flick K
  • Native low density lipoprotein promotes lipid raft formation in macrophages.
    Mol Med Rep Volume: 13 Page(s): 2087 - 2093
    03/01/2016 Authors: Song J; Ping L-Y; Duong DM; Gao X-Y; He C-Y; Wei L; Wu J-Z
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