Publications

• Patterns and Cofactors of Polyfunctional Mycobacteria-Specific T-Cell Response Restoration Following 6-Month Antiretroviral Treatment in Children With HIV.
  J Infect Dis Volume: 231 Page(s): 957 - 966
  04/15/2025 Authors: Day CL; Njuguna IN; Cranmer LM; Whatney WE; Pearson RA; Lindestam Arlehamn CS; Sette A; LaCourse SM; Escudero JN; Sasser LE
• HIV-related Differences in Placental Immunology: Data From the PRACHITi Cohort in Pune, India.
  Open Forum Infect Dis Volume: 12 Page(s): ofaf047
  03/01/2025 Authors: Mathad JS; Alexander M; Bhosale R; Naik S; Cranmer LM; Kulkarni V; Busch S; Chalem A; Gitlin E; Lei J
• High Intention to Vaccinate Against Tuberculosis During Pregnancy and Lactation: Understanding Vaccine-specific Maternal Immunization Acceptance in Amhara, Ethiopia.
  Pediatr Infect Dis J Volume: 44 Page(s): S135 - S140
  02/01/2025 Authors: Quincer EM; Gobezayehu AG; Belew ML; Endalamaw LA; Tesfaye YA; Shiferaw M; Hussen SA; Cranmer JN; Omer SB; Cranmer LM
• The underestimated burden of tuberculosis in children.
  Lancet Child Adolesc Health Volume: 8 Page(s): 845 - 847
  12/01/2024 Authors: Salazar-Austin N; Cranmer LM
• Human Immunodeficiency Virus and Breastfeeding: Clinical Considerations and Mechanisms of Transmission in the Modern Era of Combined Antiretroviral Therapy.
  Clin Perinatol Volume: 51 Page(s): 783 - 799
  12/01/2024 Authors: Powers JS; Kihanga M; Cranmer LM
• Effect of tuberculosis-HIV co-treatment on clinical and growth outcomes among hospitalized children newly initiating antiretroviral therapy.
  AIDS Volume: 38 Page(s): 579 - 588
  03/15/2024 Authors: Cherkos AS; Cranmer LM; Njuguna I; LaCourse SM; Mugo C; Moraa H; Maleche-Obimbo E; Enquobahrie DA; Richardson BA; Wamalwa D
• Prenatal Maternal Immunization for Infant Protection: A Review of the Vaccines Recommended, Infant Immunity and Future Research Directions.
  Pathogens Volume: 13
  02/23/2024 Authors: Quincer EM; Cranmer LM; Kamidani S
• The effect of antenatal isoniazid preventive therapy on birth outcomes in Western Kenya.
  Int J Tuberc Lung Dis Volume: 27 Page(s): 906 - 911
  12/01/2023 Authors: Quincer EM; Lyland A; Onyango D; LaCourse SM; Figueroa J; John-Stewart GC; Cranmer LM
• An effective vaccine is only the first step: the need to create and sustain demand for TB vaccines.
  Int J Tuberc Lung Dis Volume: 27 Page(s): 718 - 720
  10/01/2023 Authors: Nelson KN; Shah NS; Cranmer LM; Vasudevan L; Bednarczyk RA
• Updated considerations in the diagnosis and management of tuberculosis infection and disease: integrating the latest evidence-based strategies.
  Expert Rev Anti Infect Ther Volume: 21 Page(s): 595 - 616
  06/01/2023 Authors: Graciaa DS; Schechter MC; Fetalvero KB; Cranmer LM; Kempker RR; Castro KG
• Development of treatment-decision algorithms for children evaluated for pulmonary tuberculosis: an individual participant data meta-analysis.
  Lancet Child Adolesc Health Volume: 7 Page(s): 336 - 346
  05/01/2023 Authors: Gunasekera KS; Marcy O; Muoz J; Lopez-Varela E; Sekadde MP; Franke MF; Bonnet M; Ahmed S; Amanullah F; Anwar A
• Cumulative Mycobacterium tuberculosis Infection Incidence (Measured Primarily by Tuberculin Skin Test) Among Infants With Human Immunodeficiency Virus Exposure: Observational Follow-up of an Isoniazid Prophylaxis Trial.
  Clin Infect Dis Volume: 75 Page(s): 2253 - 2256
  12/19/2022 Authors: LaCourse SM; Escudero JN; Mecha J; Warr AJ; Richardson BA; Carimo N; Cranmer LM; Maleche-Obimbo E; Matemo D; Kinuthia J
• Development of a Clinical Prediction Score Including Monocyte-to-Lymphocyte Ratio to Inform Tuberculosis Treatment Among Children With HIV: A Multicountry Study.
  Open Forum Infect Dis Volume: 9 Page(s): ofac548
  11/01/2022 Authors: Malik AA; Gandhi NR; Marcy O; Walters E; Tejiokem M; Chau GD; Omer SB; Lash TL; Becerra MC; Njuguna IN
• Brief Report: Performance of Tuberculosis Symptom Screening Among Hospitalized ART-Naive Children With HIV in Kenya.
  J Acquir Immune Defic Syndr Volume: 91 Page(s): 280 - 284
  11/01/2022 Authors: Cranmer LM; Njuguna IN; LaCourse SM; Figueroa J; Gillespie S; Maleche-Obimbo E; Otieno V; Mugo C; Okinyi H; Benki-Nugent S
• Developing tuberculosis vaccines for people with HIV: consensus statements from an international expert panel.
  Lancet HIV Volume: 9 Page(s): e791 - e800
  11/01/2022 Authors: Miner MD; Hatherill M; Mave V; Gray GE; Nachman S; Read SW; White RG; Hesseling A; Cobelens F; Patel S
• What's Old and New in Tuberculosis Vaccines for Children.
  J Pediatric Infect Dis Soc Volume: 11 Page(s): S110 - S116
  10/31/2022 Authors: Cranmer LM; Cotton MF; Day CL; Nemes E
• Closing the Brief Case: Furuncular Myiasis Caused by the Third-Instar Larva of a Bot Fly in the Genus Cuterebra.
  J Clin Microbiol Volume: 60 Page(s): e0230821
  09/21/2022 Authors: Mathison BA; Cramner LM; Cox G; Jerris RC; Couturier MR
• The Brief Case: Furuncular Myiasis Caused by the Third-Instar Larva of a Bot Fly in the Genus Cuterebra.
  J Clin Microbiol Volume: 60 Page(s): e0230721
  09/21/2022 Authors: Mathison BA; Cramner LM; Cox G; Jerris RC; Couturier MR
• Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples.
  Nat Biomed Eng Volume: 6 Page(s): 979 - 991
  08/01/2022 Authors: Zheng W; LaCourse SM; Song B; Singh DK; Khanna M; Olivo J; Stern J; Escudero JN; Vergara C; Zhang F
• CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study.
  Lancet Microbe Volume: 3 Page(s): e482 - e492
  07/01/2022 Authors: Huang Z; LaCourse SM; Kay AW; Stern J; Escudero JN; Youngquist BM; Zheng W; Vambe D; Dlamini M; Mtetwa G
• A CD4+ TNF+ monofunctional memory T-cell response to BCG vaccination is associated with Mycobacterium tuberculosis infection in infants exposed to HIV.
  EBioMedicine Volume: 80 Page(s): 104023
  06/01/2022 Authors: Warr AJ; Anterasian C; Shah JA; De Rosa SC; Nguyen FK; Maleche-Obimbo E; Cranmer LM; Matemo D; Mecha J; Kinuthia J
• Cytomegalovirus Viremia and Clinical Outcomes in Kenyan Children Diagnosed With Human Immunodeficiency Virus (HIV) in Hospital.
  Clin Infect Dis Volume: 74 Page(s): 1237 - 1246
  04/09/2022 Authors: Wamalwa D; Njuguna I; Maleche-Obimbo E; Begnel E; Chebet DJ; Onyango JA; Cranmer LM; Huang M-L; Richardson BA; Boeckh M
• Support for Establishing Best Practices for Breastfeeding in the Current HIV/ART Era.
  J Pediatric Infect Dis Soc Volume: 11 Page(s): 90 - 91
  03/24/2022 Authors: Cranmer LM; Chung MH; Chahroudi A
• A Randomized Controlled Trial of Isoniazid to Prevent Mycobacterium tuberculosis Infection in Kenyan Human Immunodeficiency Virus-Exposed Uninfected Infants.
  Clin Infect Dis Volume: 73 Page(s): e337 - e344
  07/15/2021 Authors: LaCourse SM; Richardson BA; Kinuthia J; Warr AJ; Maleche-Obimbo E; Matemo D; Cranmer LM; Mecha J; Escudero JN; Hawn TR
• Incidence and co-factors of Mtb infection in first two years of life: observational follow-up of a randomized controlled trial of INH to prevent primary Mtb infection among HIV-exposed uninfected children
  Volume: 24 Page(s): 21 - 21
  07/01/2021 Authors: LaCourse S; Escudero J; Carimo N; Richardson B; Cranmer L; Warr A; Maleche-Obimbo E; Mecha J; Matemo D; Kinuthia J
• Risk Factors for Adverse Events in Household Contacts Prescribed Preventive Treatment for Drug-resistant Tuberculosis Exposure.
  Clin Infect Dis Volume: 72 Page(s): 1709 - 1715
  05/18/2021 Authors: Malik AA; Becerra MC; Lash TL; Cranmer LM; Omer SB; Fuad J; Siddiqui S; Amanullah F; Jaswal M; Salahuddin N
• Effectiveness of Preventive Therapy for Persons Exposed at Home to Drug-Resistant Tuberculosis, Karachi, Pakistan.
  Emerg Infect Dis Volume: 27 Page(s): 805 - 812
  03/01/2021 Authors: Malik AA; Gandhi NR; Lash TL; Cranmer LM; Omer SB; Ahmed JF; Siddiqui S; Amanullah F; Khan AJ; Keshavjee S
• Newly diagnosed HIV positive children: a unique index case to improve HIV diagnosis and linkage to care of parents.
  AIDS Care Volume: 32 Page(s): 1400 - 1405
  11/01/2020 Authors: Neary J; Njuguna IN; Cranmer LM; Otieno VO; Mugo C; Okinyi HM; Benki-Nugent S; Richardson BA; Stern J; Maleche-Obimbo E
• Infant TB Infection Prevention Study (iTIPS): a randomised trial protocol evaluating isoniazid to prevent M. tuberculosis infection in HIV-exposed uninfected children.
  BMJ Open Volume: 10 Page(s): e034308
  01/21/2020 Authors: LaCourse SM; Richardson BA; Kinuthia J; Warr AJ; Maleche-Obimbo E; Matemo D; Cranmer LM; Escudero JN; Hawn TR; John-Stewart GC
• Brief Report: High Programmatic Isoniazid Preventive Therapy (IPT) Use in Pregnancy Among HIV-Infected Women.
  J Acquir Immune Defic Syndr Volume: 82 Page(s): 41 - 45
  09/01/2019 Authors: LaCourse SM; Wagner AD; Cranmer LM; Copeland A; Maleche-Obimbo E; Richardson BA; Matemo D; Kinuthia J; John-Stewart G
• Brief Report: Cofactors of Mortality Among Hospitalized HIV-Infected Children Initiating Antiretroviral Therapy in Kenya.
  J Acquir Immune Defic Syndr Volume: 81 Page(s): 138 - 144
  06/01/2019 Authors: Njuguna IN; Cranmer LM; Wagner AD; LaCourse SM; Mugo C; Benki-Nugent S; Richardson BA; Stern J; Maleche-Obimbo E; Wamalwa DC
• M. tuberculosis antigen-specific T-cell function in breast milk of HIV-infected mothers
  Volume: 202
  05/01/2019 Authors: Warr AJ; Shah J; LaCourse S; Kinuthia J; Maleche-Obimbo E; Cranmer L; Felicia N; Matemo D; John-Stewart G; Hawn T
• Monocyte-to-Lymphocyte Ratio Is Associated With Tuberculosis Disease and Declines With Anti-TB Treatment in HIV-Infected Children.
  J Acquir Immune Defic Syndr Volume: 80 Page(s): 174 - 181
  02/01/2019 Authors: Choudhary RK; Wall KM; Njuguna I; Pavlinac PB; LaCourse SM; Otieno V; Gatimu J; Stern J; Maleche-Obimbo E; Wamalwa D
• High Incidence of Tuberculosis Infection in HIV-exposed Children Exiting an Isoniazid Preventive Therapy Trial.
  Pediatr Infect Dis J Volume: 37 Page(s): e254 - e256
  10/01/2018 Authors: Cranmer LM; Draper HR; Mandalakas AM; Kim S; McSherry G; Krezinski E; Coetzee J; Mitchell C; Nachman S; van der Linde M
• Improved Neurodevelopment After Initiation of Antiretroviral Therapy in Human Immunodeficiency Virus-infected Children.
  Pediatr Infect Dis J Volume: 37 Page(s): 916 - 922
  09/01/2018 Authors: Gmez LA; Crowell CS; Njuguna I; Cranmer LM; Wamalwa D; Chebet D; Otieno V; Maleche-Obimbo E; Gladstone M; John-Stewart G
• Urine Tuberculosis Lipoarabinomannan Predicts Mortality in Hospitalized Human Immunodeficiency Virus-Infected Children.
  Clin Infect Dis Volume: 66 Page(s): 1798 - 1801
  05/17/2018 Authors: LaCourse SM; Cranmer LM; Njuguna IN; Gatimu J; Stern J; Maleche-Obimbo E; Walson JL; Wamalwa D; John-Stewart GC; Pavlinac PB
• Stool Xpert MTB/RIF and urine lipoarabinomannan for the diagnosis of tuberculosis in hospitalized HIV-infected children.
  AIDS Volume: 32 Page(s): 69 - 78
  01/02/2018 Authors: LaCourse SM; Pavlinac PB; Cranmer LM; Njuguna IN; Mugo C; Gatimu J; Stern J; Walson JL; Maleche-Obimbo E; Oyugi J
• Symptom screening for active tuberculosis in pregnant women living with HIV.
  Cochrane Database Syst Rev Volume: 2018
  01/01/2018 Authors: LaCourse SM; Cranmer LM; Bekker A; Steingart KR; Black D; Horne DJ; Oren E; Pals S; Modi S; Mathad J
• Urgent versus post-stabilisation antiretroviral treatment in hospitalised HIV-infected children in Kenya (PUSH): a randomised controlled trial.
  Lancet HIV Volume: 5 Page(s): e12 - e22
  01/01/2018 Authors: Njuguna IN; Cranmer LM; Otieno VO; Mugo C; Okinyi HM; Benki-Nugent S; Richardson B; Stern J; Maleche-Obimbo E; Wamalwa DC
• Pediatric Dental Clinic-Associated Outbreak of Mycobacterium abscessus Infection.
  J Pediatric Infect Dis Soc Volume: 6 Page(s): e116 - e122
  09/01/2017 Authors: Hatzenbuehler LA; Tobin-D'Angelo M; Drenzek C; Peralta G; Cranmer LC; Anderson EJ; Milla SS; Abramowicz S; Yi J; Hilinski J
• Infant/child rapid serology tests fail to reliably assess HIV exposure among sick hospitalized infants.
  AIDS Volume: 31 Page(s): F1 - F7
  07/17/2017 Authors: Wagner AD; Njuguna IN; Andere RA; Cranmer LM; Okinyi HM; Benki-Nugent S; Chohan BH; Maleche-Obimbo E; Wamalwa DC; John-Stewart GC
• Effect of Pregnancy on Interferon Gamma Release Assay and Tuberculin Skin Test Detection of Latent TB Infection Among HIV-Infected Women in a High Burden Setting.
  J Acquir Immune Defic Syndr Volume: 75 Page(s): 128 - 136
  05/01/2017 Authors: LaCourse SM; Cranmer LM; Matemo D; Kinuthia J; Richardson BA; Horne DJ; John-Stewart G
• Integrating tuberculosis screening in Kenyan Prevention of Mother-To-Child Transmission programs.
  Int J Tuberc Lung Dis Volume: 21 Page(s): 256 - 262
  03/01/2017 Authors: Cranmer LM; Langat A; Ronen K; McGrath CJ; LaCourse S; Pintye J; Odeny B; Singa B; Katana A; Nganga L
• Hospitalized Children Reveal Health Systems Gaps in the Mother-Child HIV Care Cascade in Kenya.
  AIDS Patient Care STDS Volume: 30 Page(s): 119 - 124
  03/01/2016 Authors: Njuguna IN; Wagner AD; Cranmer LM; Otieno VO; Onyango JA; Chebet DJ; Okinyi HM; Benki-Nugent S; Maleche-Obimbo E; Slyker JA
• Tuberculosis Case Finding in HIV-Infected Pregnant Women in Kenya Reveals Poor Performance of Symptom Screening and Rapid Diagnostic Tests.
  J Acquir Immune Defic Syndr Volume: 71 Page(s): 219 - 227
  02/01/2016 Authors: LaCourse SM; Cranmer LM; Matemo D; Kinuthia J; Richardson BA; John-Stewart G; Horne DJ
• Mycobacterium tuberculosis Bacteremia Among Acutely Febrile Children in Western Kenya.
  Am J Trop Med Hyg Volume: 93 Page(s): 1087 - 1091
  11/01/2015 Authors: Pavlinac PB; Naulikha JM; John-Stewart GC; Onchiri FM; Okumu AO; Sitati RR; Cranmer LM; Lokken EM; Singa BO; Walson JL
• Incidence and correlates of tuberculosis IGRA conversion among HIV-infected postpartum women.
  Int J Tuberc Lung Dis Volume: 19 Page(s): 792 - 798
  07/01/2015 Authors: Jonnalagadda S; LaCourse SM; Otieno P; Lohman-Payne B; Maleche-Obimbo E; Cranmer LM; John-Stewart GC
• Tuberculosis interferon-gamma responses in the breast milk of human immunodeficiency virus infected mothers.
  Int J Tuberc Lung Dis Volume: 19 Page(s): 141 - 143
  02/01/2015 Authors: Cranmer LM; Kanyugo M; Lohman-Payne B; Tapia K; John-Stewart GC
• High prevalence of tuberculosis infection in HIV-1 exposed Kenyan infants.
  Pediatr Infect Dis J Volume: 33 Page(s): 401 - 406
  04/01/2014 Authors: Cranmer LM; Kanyugo M; Jonnalagadda SR; Lohman-Payne B; Sorensen B; Maleche Obimbo E; Wamalwa D; John-Stewart GC
• Consistency of Mycobacterium tuberculosis-specific interferon-gamma responses in HIV-1-infected women during pregnancy and postpartum.
  Infect Dis Obstet Gynecol Volume: 2012 Page(s): 950650
  01/01/2012 Authors: Jonnalagadda SR; Brown E; Lohman-Payne B; Wamalwa D; Farquhar C; Tapia K; Cranmer LM; John-Stewart GC
• Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy.
  Proc Natl Acad Sci U S A Volume: 106 Page(s): 9403 - 9408
  06/09/2009 Authors: Dinoso JB; Kim SY; Wiegand AM; Palmer SE; Gange SJ; Cranmer L; O'Shea A; Callender M; Spivak A; Brennan T
• Identification of nevirapine-resistant HIV-1 in the latent reservoir after single-dose nevirapine to prevent mother-to-child transmission of HIV-1.
  J Infect Dis Volume: 199 Page(s): 1301 - 1309
  05/01/2009 Authors: Wind-Rotolo M; Durand C; Cranmer L; Reid A; Martinson N; Doherty M; Jilek BL; Kagaayi J; Kizza A; Pillay V
• Knowledge and management of fever among Latino parents.
  Clin Pediatr (Phila) Volume: 48 Page(s): 183 - 189
  03/01/2009 Authors: Crocetti M; Sabath B; Cranmer L; Gubser S; Dooley D
• Sex-based differences in T lymphocyte responses in HIV-1-seropositive individuals.
  J Infect Dis Volume: 191 Page(s): 881 - 885
  03/15/2005 Authors: Sterling TR; Pisell-Noland T; Perez JL; Astemborski J; McGriff JR; Nutting L; Hoover DR; Vlahov D; Bollinger RC