LOU ANN BROWN PhD
- Department of Pediatrics
Professor
- (404) 727-5739
- lbrow03@emory.edu
- Website
-
Emory University, Atlanta
Pediatrics
2015 Uppergate Dr.
Academic Appointment
- Director -- Office of Postdoctoral Education, School of Medicine, Emory University
- Professor (Tenured), Department of Pediatrics, Emory University
Education
Degrees
- PhD from St. Louis University
- BS from University of North Carolina-Charlotte
Research
Focus
- Alcohol abuse increases the morbidity and mortality from acute lung injury and we demonstrated a critical role for pulmonary glutathione depletion in that increased sensitivity. We have examined the multiple mechanisms by which chronic alcohol abuse depletes pulmonary glutathione and results in sub-acute defects in pulmonary function as it relates to alveolar macrophages, pulmonary alveolar type II cells and pulmonary microvascular endothelial cells.
Publications
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Arginine Therapy for Pain in Sickle Cell Disease: A Phase-2 Randomized, Placebo-Controlled Trial.
Am J Hematol
04/24/2025 Authors: Morris CR; Hatabah D; Korman R; Gillespie S; Bakshi N; Brown LA; Harris F; Leake D; Rees CA; Khemani K -
Ethanol exposure during differentiation of human induced pluripotent stem cells reduces cardiomyocyte generation and alters metabolism.
Life Sci Volume: 364 Page(s): 123434
03/01/2025 Authors: Man K; Fu L; Lane A; Harris F; Reid O; Armand LC; Forghani P; Wu R; Faundez V; Brown LA -
Cobalamin Deficiency in Children and Adolescents with Sickle Cell Disease.
Nutrients Volume: 17
02/06/2025 Authors: Hatabah D; Krieger R; Brown LA; Harris F; Korman R; Reyes L; Umana J; Benedit L; Wynn BA; Rees CA -
Impact of arginine therapy on kyotorphin in children with sickle cell disease and vaso-occlusive pain.
Blood Adv Volume: 8 Page(s): 3267 - 3271
06/25/2024 Authors: Korman R; Hatabah D; Brown LA; Harris F; Wilkinson H; Rees CA; Bakshi N; Archer DR; Dampier C; Morris CR -
Liposomal Glutathione Augments Immune Defenses against Respiratory Syncytial Virus in Neonatal Mice Exposed in Utero to Ethanol.
Antioxidants (Basel) Volume: 13
01/23/2024 Authors: Gauthier TW; Ping X-D; Harris FL; Brown LAS -
The inflammatory profiles of pulmonary alveolar macrophages and alveolar type 2 cells in SCD.
Exp Biol Med (Maywood) Volume: 248 Page(s): 1013 - 1023
06/01/2023 Authors: Gbotosho OT; Li W; Joiner CH; Brown LAS; Hyacinth HI -
Arginine Dysregulation and Myocardial Dysfunction in a Mouse Model and Children with Chronic Kidney Disease.
Nutrients Volume: 15
04/30/2023 Authors: Reyes LZ; Winterberg PD; George RP; Kelleman M; Harris F; Jo H; Brown LAS; Morris CR -
Pharmacological reversal of post-transcriptional alterations implicated in alcohol-induced alveolar macrophage dysfunction.
Alcohol Volume: 106 Page(s): 30 - 43
02/01/2023 Authors: Yeligar SM; Harris FL; Brown LAS; Hart CM -
Increasing nitric oxide bioavailability fails to improve collateral vessel formation in humanized sickle cell mice.
Lab Invest Volume: 102 Page(s): 805 - 813
08/01/2022 Authors: Lewis CV; Sellak H; Hansen L; Joseph G; Hurtado J; Archer DR; Jun H-W; Brown LA; Taylor WR -
ASSESSING THE INCIDENCE OF POOR BIRTH OUTCOMES AND IN UTERO ALCOHOL EXPOSURE WITH A BIOMARKER (PHOSPHATIDYLETHANOL): AN OBSERVATIONAL STUDY IN RUSSIA
Volume: 46 Page(s): 147A - 147A
06/01/2022 Authors: Capasso A; Marianian A; Belskikh A; Protopopova NV; Atalyan A; Markova D; Zolotareva MM; Kalkova AN; Rezvina NY; Brown LA -
Secretory phospholipase A2 in SARS-CoV-2 infection and multisystem inflammatory syndrome in children (MIS-C).
Exp Biol Med (Maywood) Volume: 246 Page(s): 2543 - 2552
12/01/2021 Authors: Kuypers FA; Rostad CA; Anderson EJ; Chahroudi A; Jaggi P; Wrammert J; Mantus G; Basu R; Harris F; Hanberry B -
Pioglitazone Reverses Alcohol-Induced Alveolar Macrophage Phagocytic Dysfunction.
J Immunol Volume: 207 Page(s): 483 - 492
07/15/2021 Authors: Yeligar SM; Mehta AJ; Harris FL; Brown LAS; Hart CM -
Altered amino acid profile in patients with SARS-CoV-2 infection.
Proc Natl Acad Sci U S A Volume: 118
06/22/2021 Authors: Rees CA; Rostad CA; Mantus G; Anderson EJ; Chahroudi A; Jaggi P; Wrammert J; Ochoa JB; Ochoa A; Basu RK -
Alcohol induces mitochondrial derangements in alveolar macrophages by upregulating NADPH oxidase 4.
Alcohol Volume: 90 Page(s): 27 - 38
02/01/2021 Authors: Morris NL; Harris FL; Brown LAS; Yeligar SM -
Impact of arginine therapy on mitochondrial function in children with sickle cell disease during vaso-occlusive pain.
Blood Volume: 136 Page(s): 1402 - 1406
09/17/2020 Authors: Morris CR; Brown LAS; Reynolds M; Dampier CD; Lane PA; Watt A; Kumari P; Harris F; Manoranjithan S; Mendis RD -
Role of zinc insufficiency in fetal alveolar macrophage dysfunction and RSV exacerbation associated with fetal ethanol exposure.
Alcohol Volume: 80 Page(s): 5 - 16
11/01/2019 Authors: Johnson JK; Harris FL; Ping X-D; Gauthier TW; Brown LAS -
Targeting HIF-1 in combination with PPAR activation and postnatal factors promotes the metabolic maturation of human induced pluripotent stem cell-derived cardiomyocytes.
J Mol Cell Cardiol Volume: 132 Page(s): 120 - 135
07/01/2019 Authors: Gentillon C; Li D; Duan M; Yu W-M; Preininger MK; Jha R; Rampoldi A; Saraf A; Gibson GC; Qu C-K -
Cardiac Toxicity From Ethanol Exposure in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Volume: 169 Page(s): 280 - 292
05/01/2019 Authors: Rampoldi A; Singh M; Wu Q; Duan M; Jha R; Maxwell JT; Bradner JM; Zhang X; Saraf A; Miller GW -
ANTIOXIDANTS IMPROVE LUNG IMMUNITY AS WELL AS T-CELL PROLIFERATION AND ACTIVATION PROFILES IN HIV-1 IMMUNE NON-RESPONDERS
Volume: 67 Page(s): 612 - 612
02/01/2019 Authors: Ahmed M; Cribbs SK; Staitieh BS; Brown L; Paiardini M; King C; Marconi V; Guidot D -
Children with Neutrophil-Predominant Severe Asthma Have Proinflammatory Neutrophils With Enhanced Survival and Impaired Clearance.
J Allergy Clin Immunol Pract Volume: 7 Page(s): 516 - 525.e6
02/01/2019 Authors: Grunwell JR; Stephenson ST; Tirouvanziam R; Brown LAS; Brown MR; Fitzpatrick AM -
Ex Vivo Vitamin D Stimulation of Alveolar Macrophage Phagocytosis Index in People Living with HIV, Stratified by Smoking Status
Volume: 199
01/01/2019 Authors: Han J; Cribbs SK; Guidot DM; Tangpricha V; Martin GS; Brown LS -
Oxidative stress in critically ill ventilated adults: effects of vitamin D3 and associations with alveolar macrophage function.
Eur J Clin Nutr Volume: 72 Page(s): 744 - 751
05/01/2018 Authors: Han JE; Alvarez JA; Staitieh B; Tangpricha V; Hao L; Ziegler TR; Martin GS; Brown LAS -
Renal protection by atorvastatin in a murine model of sickle cell nephropathy.
Br J Haematol Volume: 181 Page(s): 111 - 121
04/01/2018 Authors: Zahr RS; Chappa P; Yin H; Brown LA; Ataga KI; Archer DR -
TGF-1 Suppresses the Type I IFN Response and Induces Mitochondrial Dysfunction in Alveolar Macrophages.
J Immunol Volume: 200 Page(s): 2115 - 2128
03/15/2018 Authors: Grunwell JR; Yeligar SM; Stephenson S; Ping XD; Gauthier TW; Fitzpatrick AM; Brown LAS -
Alcohol induces alveolar macrophage oxidative stress by down-regulating the expression of Nox1-related microRNA-1264
Volume: 66 Page(s): 95 - 96
02/01/2018 Authors: Yeligar SM; Hart CM; Brown LAS -
Hyperoxia induces paracellular leak and alters claudin expression by neonatal alveolar epithelial cells.
Pediatr Pulmonol Volume: 53 Page(s): 17 - 27
01/01/2018 Authors: Vyas-Read S; Vance RJ; Wang W; Colvocoresses-Dodds J; Brown LA; Koval M -
Dysregulation of Alveolar Macrophage PPAR, NADPH Oxidases, and TGF1 in Otherwise Healthy HIV-Infected Individuals.
AIDS Res Hum Retroviruses Volume: 33 Page(s): 1018 - 1026
10/01/2017 Authors: Yeligar SM; Ward JM; Harris FL; Brown LAS; Guidot DM; Cribbs SK -
Impact of high-dose vitamin D3 on plasma free 25-hydroxyvitamin D concentrations and antimicrobial peptides in critically ill mechanically ventilated adults.
Nutrition Volume: 38 Page(s): 102 - 108
06/01/2017 Authors: Han JE; Alvarez JA; Jones JL; Tangpricha V; Brown MA; Hao L; Brown LAS; Martin GS; Ziegler TR -
Impaired defenses of neonatal mouse alveolar macrophage with cftr deletion are modulated by glutathione and TGF1.
Physiol Rep Volume: 5
03/01/2017 Authors: Gauthier TW; Grunwell JR; Ping X-D; Harris FL; Brown LAS -
Ethyl linolenate is elevated in meconium of very-low-birth-weight neonates exposed to alcohol in utero.
Pediatr Res Volume: 81 Page(s): 461 - 467
03/01/2017 Authors: Gross TS; Harris F; Brown LAS; Gauthier TW -
ZINC AND S-ADENOSYLMETHIONINE MEDIATE LUNG INFLAMMATORY CYTOKINES IN OTHERWISE HEALTHY HIV-1-INFECTED INDIVIDUALS
Volume: 65 Page(s): 614 - 614
02/01/2017 Authors: Hazariwala V; Guidot D; Brown L; Harris F; Haber M; Cribbs SK -
In utero alcohol effects on foetal, neonatal and childhood lung disease.
Paediatr Respir Rev Volume: 21 Page(s): 34 - 37
01/01/2017 Authors: Gauthier TW; Brown LAS -
Systemic Corticosteroid Responses in Children with Severe Asthma: Phenotypic and Endotypic Features.
J Allergy Clin Immunol Pract Volume: 5 Page(s): 410 - 419.e4
01/01/2017 Authors: Fitzpatrick AM; Stephenson ST; Brown MR; Nguyen K; Douglas S; Brown LAS -
Loss Of Cftr Alters Alveolar Macrophage Viral Defense
Volume: 195
01/01/2017 Authors: Gauthier TW; Ping X; Anderson LJ; Moore ML; Brown L -
Respiratory Syncytial Virus Decreases The Metabolic Potential And Spare Respiratory Capacity Of Mouse Alveolar Macrophages
Volume: 195
01/01/2017 Authors: Grunwell JR; Yeligar SM; Gauthier TW; Brown L -
The Relationship Between Airway Antioxidant Levels, Alcohol Use Disorders, and Cigarette Smoking.
Alcohol Clin Exp Res Volume: 40 Page(s): 2147 - 2160
10/01/2016 Authors: Burnham EL; McNally A; Gaydos J; Brown LAS -
Maternal Alcohol Use During Pregnancy and Associated Morbidities in Very Low Birth Weight Newborns.
Am J Med Sci Volume: 352 Page(s): 368 - 375
10/01/2016 Authors: Gauthier TW; Guidot DM; Kelleman MS; McCracken CE; Brown LAS -
PREDIABETES AND REDOX IMBALANCE IN YOUNG CHILDREN WITH CF
PEDIATRIC PULMONOLOGY Volume: 51 Page(s): 445 - 445
10/01/2016 Authors: Hunt WR; Guentert DE; Brown LS; Stecenko A -
Alcohol and lung injury and immunity.
Alcohol Volume: 55 Page(s): 51 - 59
09/01/2016 Authors: Yeligar SM; Chen MM; Kovacs EJ; Sisson JH; Burnham EL; Brown LAS -
Peroxisome Proliferator-Activated Receptor Regulates Chronic Alcohol-Induced Alveolar Macrophage Dysfunction.
Am J Respir Cell Mol Biol Volume: 55 Page(s): 35 - 46
07/01/2016 Authors: Yeligar SM; Mehta AJ; Harris FL; Brown LAS; Hart CM -
High Dose Vitamin D Administration in Ventilated Intensive Care Unit Patients: A Pilot Double Blind Randomized Controlled Trial.
J Clin Transl Endocrinol Volume: 4 Page(s): 59 - 65
06/01/2016 Authors: Han JE; Jones JL; Tangpricha V; Brown MA; Brown LAS; Hao L; Hebbar G; Lee MJ; Liu S; Ziegler TR -
Impact of Vitamin D Status and High-dose Vitamin D-3 Administration on the Plasma Metabolome in Critically Ill Adults
Volume: 30
04/01/2016 Authors: Perry-Walker K; Walker DI; Alvarez JA; Han JE; Jones JL; Hao L; Li S; Uppal K; Tran VT; Brown L -
Increased tgf beta 1 Alters Cellular Glutathione And oxidant Stress in neonatal Alveolar Macrophage With Cftr Mutation
Volume: 193
01/01/2016 Authors: Gauthier TW; Ping X; Brown LS -
Peroxisome Proliferator-Activated Receptor Gamma Activation Attenuates Alcohol-Induced Alveolar Macrophage Mitochondrial Derangements And Phagocytic Dysfunction Via Mir-92a/b Up-Regulation
Volume: 193
01/01/2016 Authors: Yeligar SM; Harris FL; Brown LS; Hart C -
Dietary Supplementation With S-Adenosylmethionine And Zinc Attenuates Hiv-Induced Alveolar Macrophage Phagocytic Dysfunction
Volume: 193
01/01/2016 Authors: Yeligar SM; Cribbs SK; Guidot DM; Brown LS -
Modulation Of Alveolar Macrophage Immune Function By Fatty Acid Ethyl Esters
Volume: 193
01/01/2016 Authors: Gauthier TW; Ping X; Brown LS -
Maternal Alcohol Use And Associated Bpd/death In The Very Low Birthweight Newborn
Volume: 193
01/01/2016 Authors: Gauthier TW; Guidot DM; McCracken CE; Kelleman MS; Brown LS -
Summary of the 2014 Alcohol and Immunology Research Interest Group (AIRIG) meeting.
Alcohol Volume: 49 Page(s): 767 - 772
12/01/2015 Authors: Hammer AM; Morris NL; Cannon AR; Shults JA; Curtis B; Casey CA; Sueblinvong V; Persidsky Y; Nixon K; Brown LA -
Cysteine oxidation impairs systemic glucocorticoid responsiveness in children with difficult-to-treat asthma.
J Allergy Clin Immunol Volume: 136 Page(s): 454 - 61.e9
08/01/2015 Authors: Stephenson ST; Brown LAS; Helms MN; Qu H; Brown SD; Brown MR; Fitzpatrick AM -
The relative balance of GM-CSF and TGF-1 regulates lung epithelial barrier function.
Am J Physiol Lung Cell Mol Physiol Volume: 308 Page(s): L1212 - L1223
06/15/2015 Authors: Overgaard CE; Schlingmann B; Dorsainvil White S; Ward C; Fan X; Swarnakar S; Brown LAS; Guidot DM; Koval M -
Characterization of a high TNF- phenotype in children with moderate-to-severe asthma.
J Allergy Clin Immunol Volume: 135 Page(s): 1651 - 1654
06/01/2015 Authors: Brown SD; Brown LA; Stephenson S; Dodds JC; Douglas SL; Qu H; Fitzpatrick AM -
Dynamics of Increasing IFN- Exposure on Murine MH-S Cell-Line Alveolar Macrophage Phagocytosis of Streptococcus pneumoniae.
J Interferon Cytokine Res Volume: 35 Page(s): 474 - 479
06/01/2015 Authors: Mina MJ; Brown LAS; Klugman KP -
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR)gamma ACTIVATION IMPROVES ALVEOLAR MACROPHAGE BACTERIAL CLEARANCE BY DOWN-REGULATING OXIDATIVE STRESS
Volume: 39 Page(s): 274A - 274A
06/01/2015 Authors: Yeligar SM; Harris FL; Brown LA; Hart CM -
FATTY ACID ETHYL ESTERS ARE ELEVATED IN MECONIUM FROM PREMATURE NEWBORNS EXPOSED TO ALCOHOL IN UTERO
Volume: 39 Page(s): 226A - 226A
06/01/2015 Authors: Gross TS; Gauthier TW; Harris FL; Brown LAS -
Oxidized glutathione (GSSG) inhibits epithelial sodium channel activity in primary alveolar epithelial cells.
Am J Physiol Lung Cell Mol Physiol Volume: 308 Page(s): L943 - L952
05/01/2015 Authors: Downs CA; Kreiner L; Zhao X-M; Trac P; Johnson NM; Hansen JM; Brown LA; Helms MN -
Effect of High-Dose Vitamin D on Antimicrobial Peptides in Ventilator-Dependent Critically Ill Patients
Volume: 29
04/01/2015 Authors: Jones J; Alvarez J; Han J; Hao L; Chiang E; Brown L; Tangpricha V; Martin G; Ziegler T -
Fatty acid ethyl esters disrupt neonatal alveolar macrophage mitochondria and derange cellular functioning.
Alcohol Clin Exp Res Volume: 39 Page(s): 434 - 444
03/01/2015 Authors: Mohan SS; Ping XD; Harris FL; Ronda NJ; Brown LAS; Gauthier TW -
Alcohol and inflammatory responses: summary of the 2013 Alcohol and Immunology Research Interest Group (AIRIG) meeting.
Alcohol Volume: 49 Page(s): 1 - 6
02/01/2015 Authors: Morris NL; Ippolito JA; Curtis BJ; Chen MM; Friedman SL; Hines IN; Haddad GE; Chang SL; Brown LA; Waldschmidt TJ -
The role of donor chronic alcohol abuse in the development of primary graft dysfunction in lung transplant recipients.
Am J Med Sci Volume: 349 Page(s): 117 - 123
02/01/2015 Authors: Pelaez A; Mitchell PO; Shah NS; Force SD; Elon L; Brown LAS; Guidot DM -
Placental Fatty Acid ethyl esters are elevated with maternal alcohol use in pregnancies complicated by prematurity.
PLoS One Volume: 10 Page(s): e0126552
01/01/2015 Authors: Gauthier TW; Mohan SS; Gross TS; Harris FL; Guidot DM; Brown LAS -
Comparison of Glutathione, Cysteine, and Their Redox Potentials in the Plasma of Critically Ill and Healthy Children.
Front Pediatr Volume: 3 Page(s): 46
01/01/2015 Authors: Grunwell JR; Gillespie SE; Ward JM; Fitzpatrick AM; Brown LA; Gauthier TW; Hebbar KB -
Metabolic Consequences of Chronic Alcohol Abuse in Non-Smokers: A Pilot Study.
PLoS One Volume: 10 Page(s): e0129570
01/01/2015 Authors: Obianyo O; Liang Y; Burnham EL; Mehta A; Park Y; Uppal K; Harris FL; Jones DP; Brown LAS -
Correction: Placental Fatty Acid Ethyl Esters Are Elevated with Maternal Alcohol Use in Pregnancies Complicated by Prematurity.
PLoS One Volume: 10 Page(s): e0136366
01/01/2015 Authors: Gauthier TW; Mohan SS; Gross TS; Harris FL; Guidot DM; Brown LAS -
Zinc insufficiency mediates ethanol-induced alveolar macrophage dysfunction in the pregnant female mouse.
Alcohol Alcohol Volume: 50 Page(s): 30 - 38
01/01/2015 Authors: Konomi JV; Harris FL; Ping X-D; Gauthier TW; Brown LAS -
Healthy HIV-1-infected individuals on highly active antiretroviral therapy harbor HIV-1 in their alveolar macrophages.
AIDS Res Hum Retroviruses Volume: 31 Page(s): 64 - 70
01/01/2015 Authors: Cribbs SK; Lennox J; Caliendo AM; Brown LA; Guidot DM -
Receptor for advanced glycation end-products regulates lung fluid balance via protein kinase C-gp91(phox) signaling to epithelial sodium channels.
Am J Respir Cell Mol Biol Volume: 52 Page(s): 75 - 87
01/01/2015 Authors: Downs CA; Kreiner LH; Johnson NM; Brown LA; Helms MN -
The Rage Signaling Pathway In Sepsis Induced Ards: Role Of Hmgb1 And Mmps
Volume: 191
01/01/2015 Authors: Martin R; Martin GS; Harris F; Brown L; Esper AM -
A Pilot Randomized Controlled Trial Of High-Dose Vitamin D In Lung Failure
Volume: 191
01/01/2015 Authors: Han JE; Jones JL; Brown M; Tangpricha V; Brown L; Hao L; Hebbar G; Liu S; Ziegler TR; Martin GS -
Hiv Infection Induces Nadph Oxidase Expression In Alveolar Macrophages Of Otherwise Healthy Subjects
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 191
01/01/2015 Authors: Yeligar SM; Guidot DM; Brown LS; Cribbs SK -
Peroxisome Proliferator-Activated Receptor Gamma Activation With Pioglitazone Attenuates Alcohol-Induced Alveolar Macrophage Nox4 Expression And Phagocytic Dysfunction Via Mir-92a/b Up-Regulation
Volume: 191
01/01/2015 Authors: Yeligar SM; Harris FL; Brown LS; Hart CM -
OXIDATIVE STRESS IS ELEVATED IN THE PLASMA OF CRITICALLY ILL CHILDREN
CRITICAL CARE MEDICINE Volume: 42
12/01/2014 Authors: Grunwell J; Gillespie S; Ward J; Fitzpatrick A; Brown LA; Gauthier T; Hebbar K -
Pioglitazone attenuates alcohol-induced alveolar macrophage oxidative stress and dysfunction by up-regulating microRNA-92a/b
Volume: 48 Page(s): 734 - 734
11/01/2014 Authors: Yeligar SM; Harris FL; Brown LAS; Hart CM -
MODULATION OF NEONATAL ALVEOLAR MACROPHAGE IN THE CF LUNG - IMPLICATIONS FOR IMPAIRED IMMUNE DEFENSE
PEDIATRIC PULMONOLOGY Volume: 49 Page(s): 253 - 253
09/01/2014 Authors: Gauthier TW; Ping X; Brown LS -
Systemic antioxidants and lung function in asthmatics during high ozone season: a closer look at albumin, glutathione, and associations with lung function.
Clin Transl Sci Volume: 7 Page(s): 314 - 318
08/01/2014 Authors: Khatri SB; Peabody J; Burwell L; Harris F; Brown LS -
Oxidative Stress Correleates with Survival in Lung Transplantation.
Volume: 98 Page(s): 685 - 685
07/15/2014 Authors: Neujahr D; Xu J; McGill L; Harris F; Brown L; Fifadara N -
Metabolomics of bronchoalveolar lavage differentiate healthy HIV-1-infected subjects from controls.
AIDS Res Hum Retroviruses Volume: 30 Page(s): 579 - 585
06/01/2014 Authors: Cribbs SK; Park Y; Guidot DM; Martin GS; Brown LA; Lennox J; Jones DP -
Chronic ethanol exposure alters the lung proteome and leads to mitochondrial dysfunction in alveolar type 2 cells.
Am J Physiol Lung Cell Mol Physiol Volume: 306 Page(s): L1026 - L1035
06/01/2014 Authors: Alli AA; Brewer EM; Montgomery DS; Ghant MS; Eaton DC; Brown LA; Helms MN -
Oxidative Stress Correleates with Survival in Lung Transplantation.
Volume: 14 Page(s): 685 - 685
06/01/2014 Authors: Neujahr D; Xu J; McGill L; Harris F; Brown L; Fifadara N -
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR)gamma ACTIVATION IMPROVES ALCOHOL-INDUCED ALVEOLAR MACROPHAGE DYSFUNCTION VIAMODULATION OF MICRORNAS
Volume: 38 Page(s): 25A - 25A
06/01/2014 Authors: Yeligar SM; Harris FL; Brown LA; Hart CM -
DIFFERENTIALLY EXPRESSED METABOLITES IN THE BRONCHOALVEOLAR LAVAGE FLUID (BALF) OF ALCOHOLIC SUBJECTS
Volume: 38 Page(s): 66A - 66A
06/01/2014 Authors: Obianyo O; Jones DP; Brown LA -
ALTERED ALVEOLAR MITOCHONDRIAL METABOLISM IN ETHANOL-FED RATS
Volume: 38 Page(s): 66A - 66A
06/01/2014 Authors: Obianyo O; Jones DP; Brown LA -
Glutathione attenuates ethanol-induced alveolar macrophage oxidative stress and dysfunction by downregulating NADPH oxidases.
Am J Physiol Lung Cell Mol Physiol Volume: 306 Page(s): L429 - L441
03/01/2014 Authors: Yeligar SM; Harris FL; Hart CM; Brown LAS -
Hyperoxia induces alveolar epithelial-to-mesenchymal cell transition.
Am J Physiol Lung Cell Mol Physiol Volume: 306 Page(s): L326 - L340
02/15/2014 Authors: Vyas-Read S; Wang W; Kato S; Colvocoresses-Dodds J; Fifadara NH; Gauthier TW; Helms MN; Carlton DP; Brown LAS -
HEALTHY HIV-INFECTED INDIVIDUALS HARBOR HIV IN THEIR ALVEOLAR MACROPHAGES
JOURNAL OF INVESTIGATIVE MEDICINE Volume: 62 Page(s): 542 - 542
02/01/2014 Authors: Cribbs SK; Lennox J; Caliendo A; Brown L; Guidot D -
HEALTHY HIV-INFECTED INDIVIDUALS HARBOR HIV IN THEIR ALVEOLAR MACROPHAGES
JOURNAL OF INVESTIGATIVE MEDICINE Volume: 62 Page(s): 511 - 511
02/01/2014 Authors: Cribbs SK; Lennox J; Caliendo A; Brown L; Guidot D -
Exhaled breath condensate in intubated neonates--a window into the lung's glutathione status.
Respir Res Volume: 15 Page(s): 1
01/07/2014 Authors: Rosso MI; Roark S; Taylor E; Ping X; Ward JM; Roche K; McCracken C; Brown LAS; Gauthier TW -
Anti-retroviral therapy is associated with decreased alveolar glutathione levels even in healthy HIV-infected individuals.
PLoS One Volume: 9 Page(s): e88630
01/01/2014 Authors: Cribbs SK; Guidot DM; Martin GS; Lennox J; Brown LA -
Children with severe asthma have unique oxidative stress-associated metabolomic profiles.
J Allergy Clin Immunol Volume: 133 Page(s): 258-61.e1-8
01/01/2014 Authors: Fitzpatrick AM; Park Y; Brown LAS; Jones DP -
Alcohol induced mitochondrial oxidative stress and alveolar macrophage dysfunction.
Biomed Res Int Volume: 2014 Page(s): 371593
01/01/2014 Authors: Liang Y; Harris FL; Brown LAS -
Maternal Alcohol Use and the Neonate
Volume: 14 Page(s): 231 - 245
01/01/2014 Authors: Gauthier TW; Giliberti D; Mohan SS; Konomi J; Brown LAS -
Hiv Infection Induces Dysregulation Of Ppar-gamma And Tgf-beta In Alveolar Macrophages Of Otherwise Healthy Subjects
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 189
01/01/2014 Authors: Yeligar SM; Guidot DM; Brown LS; Cribbs SK -
Traffic Related Air Pollution Is Association With Alveolar Macrophage Phagocytosis In Healthy Hiv-Infected Non-Smokers
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 189
01/01/2014 Authors: Blount RJ; Huang L; Balmes JR; Brown L; Cribbs SK -
Hiv Infection And Smoking Compound Alveolar Oxidative Stress
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 189
01/01/2014 Authors: Cribbs SK; Wongtrakool C; Brown L; Guidot DM; Crothers KA -
Peroxisome Proliferator-Activated Receptor Gamma Activation With Pioglitazone Attenuates Alcohol-Induced Alveolar Macrophage Oxidative Stress And Dysfunction By Up-Regulating Mir-92a/b
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 189
01/01/2014 Authors: Yeligar SM; Harris FL; Brown LS; Hart CM -
Receptor For Advanced Glycation End-Products Regulates Lung Fluid Balance Via Pkc-Nadph Oxidase 2 Signaling To Alveolar Epithelial Sodium Channels
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 189
01/01/2014 Authors: Downs CA; Johnson N; Brown L; Helms M -
Alcohol-Mediated Oxidative Stress in the Airway: The Unique Role of Thiol Depletion
Volume: 14 Page(s): 103 - 114
01/01/2014 Authors: Yeligar SM; Liang Y; Brown LAS -
Alcohol and the Alveolar Macrophage
Volume: 14 Page(s): 63 - 81
01/01/2014 Authors: Yeligar SM; Liang Y; Brown LAS -
Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma.
Front Pharmacol Volume: 5 Page(s): 179
01/01/2014 Authors: Tuzova M; Jean J-C; Hughey RP; Brown LAS; Cruikshank WW; Hiratake J; Joyce-Brady M -
Alcohol induces mitochondrial redox imbalance in alveolar macrophages.
Free Radic Biol Med Volume: 65 Page(s): 1427 - 1434
12/01/2013 Authors: Liang Y; Harris FL; Jones DP; Brown LAS -
Glutathione Redox Regulation of Lung Epithelial Sodium Channel (ENaC) Activity
FREE RADICAL BIOLOGY AND MEDICINE Volume: 65 Page(s): S62 - S62
11/01/2013 Authors: Johnson NM; Kreiner L; Downs CA; Brown LA; Hansen JM; Helms MN -
Pioglitazone attenuates alcohol-induced alveolar macrophage oxidative stress and dysfunction by up-regulating Nox4-associated microRNAs
Volume: 47 Page(s): 576 - 576
11/01/2013 Authors: Yeligar SM; Harris FL; Brown LAS; Hart CM -
Alcoholism causes alveolar macrophage zinc deficiency and immune dysfunction.
Am J Respir Crit Care Med Volume: 188 Page(s): 716 - 723
09/15/2013 Authors: Mehta AJ; Yeligar SM; Elon L; Brown LA; Guidot DM -
PPAR gamma ACTIVATION UP-REGULATES NOX-RELATED MICRORNAS TO ATTENUATE ALCOHOL-INDUCED ALVEOLAR MACROPHAGE DYSFUNCTION
Volume: 37 Page(s): 171A - 171A
06/01/2013 Authors: Yeligar SM; Harris FL; Brown LA; Hart CM -
EFFECTS OF FETAL ALCOHOL EXPOSURE ON ZINC HOMEOSTASIS IN THE NEWBORN PULMONARY ALVEOLAR MACROPHAGE
Volume: 37 Page(s): 172A - 172A
06/01/2013 Authors: Konomi JV; Brown LA -
Inflammatory mediator patterns in tracheal aspirate and their association with bronchopulmonary dysplasia in very low birth weight neonates.
J Perinatol Volume: 33 Page(s): 383 - 387
05/01/2013 Authors: Schneibel KR; Fitzpatrick AM; Ping X-D; Brown LAS; Gauthier TW -
Effects of fetal alcohol exposure on zinc homeostasis in the newborn pulmonary alveolar macrophage
Volume: 27
04/01/2013 Authors: Konomi J; Brown LA -
Glutathione regulation of epithelial sodium channels (ENaC) in alveolar type1 and type 2 cells
Volume: 27
04/01/2013 Authors: Kreiner L; Downs CA; Brown LA; Helms MN -
EtOH consumption contributes to a 'pro-injury' environment in the alcoholic lung
Volume: 27
04/01/2013 Authors: Eaton AF; Brown LA; Helms MN -
Perinatal exposure to alcohol: implications for lung development and disease.
Paediatr Respir Rev Volume: 14 Page(s): 17 - 21
03/01/2013 Authors: Giliberti D; Mohan SS; Brown LAS; Gauthier TW -
The Transcription Factor Klf4 Is Induced In The Lung By Oxygen At Birth And Required For Perinatal Fibroblast And Myofibroblast Differentiation
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 187
01/01/2013 Authors: Joyce-Brady M; Jean J-C; George E; Kaestner K; Brown L; Spira A -
Peroxisome Proliferator-Activated Receptor Gamma Activation With Pioglitazone Attenuates Alcohol-Induced Human Alveolar Macrophage Oxidative Stress And Dysfunction
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 187
01/01/2013 Authors: Yeligar SM; Mehta AJ; Brown L; Hart M -
Hyperoxia Alters Barrier Integrity And Junctional Proteins In Neonatal Alveolar Epithelial Cells
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 187
01/01/2013 Authors: Vyas-Read S; Dodds JC; Kato S; Fifadara N; Gauthier TW; Koval M; Brown L -
Thiol Redox Disturbances Are Associated With Glucocorticoid Receptor Dysfunction In Severe, Poorly Controlled Asthma
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 187
01/01/2013 Authors: Stephenson ST; Brown L; Fitzpatrick AM -
Systemic Oxidant Stress Is Associated With Decreased Innate Immune Function In Children With Poorly Controlled Asthma
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 187
01/01/2013 Authors: Brown SD; Brown L; Fitzpatrick AM -
Transcription factor Klf4, induced in the lung by oxygen at birth, regulates perinatal fibroblast and myofibroblast differentiation.
PLoS One Volume: 8 Page(s): e54806
01/01/2013 Authors: Jean J-C; George E; Kaestner KH; Brown LAS; Spira A; Joyce-Brady M -
Diesel exhaust particles induce cysteine oxidation and s-glutathionylation in house dust mite induced murine asthma.
PLoS One Volume: 8 Page(s): e60632
01/01/2013 Authors: Lee GB; Brandt EB; Xiao C; Gibson AM; Le Cras TD; Brown LAS; Fitzpatrick AM; Khurana Hershey GK -
Chronic alcohol ingestion changes the landscape of the alveolar epithelium.
Biomed Res Int Volume: 2013 Page(s): 470217
01/01/2013 Authors: Downs CA; Trac D; Brewer EM; Brown LA; Helms MN -
Ethanol alters alveolar fluid balance via Nadph oxidase (NOX) signaling to epithelial sodium channels (ENaC) in the lung.
PLoS One Volume: 8 Page(s): e54750
01/01/2013 Authors: Downs CA; Trac DQ; Kreiner LH; Eaton AF; Johnson NM; Brown LA; Helms MN -
Alcohol and epigenetic changes: summary of the 2011 Alcohol and Immunology Research Interest Group (AIRIG) meeting.
Alcohol Volume: 46 Page(s): 783 - 787
12/01/2012 Authors: Zahs A; Curtis BJ; Waldschmidt TJ; Brown LAS; Gauthier TW; Choudhry MA; Kovacs EJ; Bird MD -
PREVALENCE OF VITAMIN D DEFICIENCY IN CRITICALLY ILL PEDIATRIC PATIENTS
Volume: 40 Page(s): U93 - U93
12/01/2012 Authors: Wittkamp M; Tangpricha V; Brown LA; Hebbar K -
Ethanol (EtOH)-induced TGF-1 and reactive oxygen species production are necessary for EtOH-induced alveolar macrophage dysfunction and induction of alternative activation.
Alcohol Clin Exp Res Volume: 36 Page(s): 1952 - 1962
11/01/2012 Authors: Brown SD; Brown LAS -
NEONATAL ALVEOLAR MACROPHAGE ARE IMPAIRED IN THE CFTR MUTATED MOUSE PUP
PEDIATRIC PULMONOLOGY Volume: 47 Page(s): 273 - 274
09/01/2012 Authors: Gauthier TW; Ping X; Brown LS -
In utero nicotine exposure promotes M2 activation in neonatal mouse alveolar macrophages.
Pediatr Res Volume: 72 Page(s): 147 - 153
08/01/2012 Authors: Wongtrakool C; Grooms K; Ping X-D; Rivera H; Ward J; Roser-Page S; Roman J; Brown LAS; Gauthier TW -
Glutathione redox control of asthma: from molecular mechanisms to therapeutic opportunities.
Antioxid Redox Signal Volume: 17 Page(s): 375 - 408
07/15/2012 Authors: Fitzpatrick AM; Jones DP; Brown LAS -
THE PULMONARY COMPLICATIONS OF ALCOHOL ABUSE: COMMON AND DEADLY
Volume: 36 Page(s): 344A - 344A
06/01/2012 Authors: Guidot DM; Joshi PC; Mehta AJ; Brown LS -
PLACENTAL FATTY ACID ETHYL ESTERS ARE INCREASED IN ALCOHOL-EXPOSED PREMATURE NEWBONS
Volume: 36 Page(s): 42A - 42A
06/01/2012 Authors: Mohan SS; Zavareh M; Brown LAS; Gauthier TW -
IMPAIRMENT OF ALVEOLAR MACROPHAGE MIGRATION IN FETAL ALCOHOL EXPOSURE: AN IN VITRO MODEL
Volume: 36 Page(s): 123A - 123A
06/01/2012 Authors: Giliberti DC; Brown LAS; Gauthier TW -
PIOGLITAZONE ATTENUATES ALCOHOL-INDUCED ALVEOLAR MACROPHAGE DYSFUNCTION VIA UP-REGULATION OF NOX4-RELATED MICRORNAS
Volume: 36 Page(s): 199A - 199A
06/01/2012 Authors: Yeligar SM; Harris FL; Brown LA; Hart CM -
Tacrolimus and Methylprednisolone Alter Pulmonary Macrophage Phagocytic Activity toward Bacteria
Volume: 12 Page(s): 214 - 214
05/01/2012 Authors: Fifadara NH; Neujahr DC; Harris F; Brown LAS -
Ethanol induces oxidative stress in alveolar macrophages via upregulation of NADPH oxidases.
J Immunol Volume: 188 Page(s): 3648 - 3657
04/15/2012 Authors: Yeligar SM; Harris FL; Hart CM; Brown LAS -
Protandim does not influence alveolar epithelial permeability or intrapulmonary oxidative stress in human subjects with alcohol use disorders.
Am J Physiol Lung Cell Mol Physiol Volume: 302 Page(s): L688 - L699
04/01/2012 Authors: Burnham EL; McCord JM; Bose S; Brown LAS; House R; Moss M; Gaydos J -
Decreased expression of acetaminophen-metabolizing enzymes and glutathione in asthmatic children after acetaminophen exposure.
J Allergy Clin Immunol Volume: 129 Page(s): 867 - 869
03/01/2012 Authors: Stephenson ST; Hadley G; Brown LAS; Fitzpatrick AM -
Airway TGF-1 and oxidant stress in children with severe asthma: association with airflow limitation.
J Allergy Clin Immunol Volume: 129 Page(s): 388 - 396.e8
02/01/2012 Authors: Brown SD; Baxter KM; Stephenson ST; Esper AM; Brown LAS; Fitzpatrick AM -
Diesel Exhaust Particles Induce Cysteine Oxidation and S-Glutathionylation in House Dust Mite Induced Murine Asthma
Volume: 129 Page(s): AB249 - AB249
02/01/2012 Authors: Lee GB; Brandt EB; Gibson AM; Le Cras TD; Brown LS; Fitzpatrick AM; Hershey GKK -
PPAR ligands regulate NADPH oxidase, eNOS, and barrier function in the lung following chronic alcohol ingestion.
Alcohol Clin Exp Res Volume: 36 Page(s): 197 - 206
02/01/2012 Authors: Wagner MC; Yeligar SM; Brown LA; Michael Hart C -
Residential proximity to a major roadway is associated with features of asthma control in children.
PLoS One Volume: 7 Page(s): e37044
01/01/2012 Authors: Brown MS; Sarnat SE; DeMuth KA; Brown LAS; Whitlock DR; Brown SW; Tolbert PE; Fitzpatrick AM -
Chronic-alcohol-abuse-induced oxidative stress in the development of acute respiratory distress syndrome.
ScientificWorldJournal Volume: 2012 Page(s): 740308
01/01/2012 Authors: Liang Y; Yeligar SM; Brown LAS -
Exhaled breath condensate: a promising source for biomarkers of lung disease.
ScientificWorldJournal Volume: 2012 Page(s): 217518
01/01/2012 Authors: Liang Y; Yeligar SM; Brown LAS -
Mitochondrial Redox Imbalance and Dysfunction Induced by Alcohol Exposure Stimulates Cell Death Pathways in Alveolar Cell Lines
Volume: 51 Page(s): S135 - S135
11/01/2011 Authors: Liang Y; Brown LA -
Rosiglitazone Attenuates Alcohol-Induced Alveolar Macrophage Oxidative Stress and Dysfunction
Volume: 51 Page(s): S117 - S117
11/01/2011 Authors: Yeligar S; Harris F; Brown LA; Hart CM -
Downregulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress.
J Allergy Clin Immunol Volume: 128 Page(s): 539 - 548
09/01/2011 Authors: Schroer KT; Gibson AM; Sivaprasad U; Bass SA; Ericksen MB; Wills-Karp M; Lecras T; Fitzpatrick AM; Brown LAS; Stringer KF -
Zinc supplementation restores PU.1 and Nrf2 nuclear binding in alveolar macrophages and improves redox balance and bacterial clearance in the lungs of alcohol-fed rats.
Alcohol Clin Exp Res Volume: 35 Page(s): 1519 - 1528
08/01/2011 Authors: Mehta AJ; Joshi PC; Fan X; Brown LAS; Ritzenthaler JD; Roman J; Guidot DM -
Thiol redox disturbances in children with severe asthma areassociated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)-like 2.
J Allergy Clin Immunol Volume: 127 Page(s): 1604 - 1611
06/01/2011 Authors: Fitzpatrick AM; Stephenson ST; Hadley GR; Burwell L; Penugonda M; Simon DM; Hansen J; Jones DP; Brown LAS -
GLUTATHIONE REDUCES ALCOHOL-INDUCED OXIDATIVE STRESS VIA DOWN-REGULATION OF NADPH OXIDASES AND TGFB(1) IN ALVEOLAR MACROPHAGES
Volume: 35 Page(s): 178A - 178A
06/01/2011 Authors: Yeligar SM; Harris FL; Hart CM; Brown LA -
ROSIGLITAZONE REDUCES ALCOHOL-INDUCED ALVEOLAR MACROPHAGE OXIDATIVE STRESS AND PHAGOCYTIC DYSFUNCTION
Volume: 35 Page(s): 48A - 48A
06/01/2011 Authors: Yeligar SM; Harris FL; Brown LA; Hart CM -
UP-REGULATION OF THE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS APPEARS TO MEDIATE ALCOHOL-INDUCED ALVEOLAR MACROPHAGE IMMUNE DYSFUNCTION
Volume: 35 Page(s): 177A - 177A
06/01/2011 Authors: Co CG; Quintero DA; Brown LAS -
FATTY ACID ETHYL ESTERS IMPAIR THE FUNCTION AND VIABILITY OF ALVEOLAR MACROPHAGES
Volume: 35 Page(s): 179A - 179A
06/01/2011 Authors: Mohan SS; Harris FL; Brown LAS; Gauthier TW -
NADPH OXIDASE REGULATION IN ALVEOLAR TYPE II CELLS IN RESPONSE TO ALCOHOL
Volume: 35 Page(s): 49A - 49A
06/01/2011 Authors: Trumer AN; Yeligar S; Brown LA -
Airway and plasma leptin and adiponectin in lean and obese asthmatics and controls.
J Asthma Volume: 48 Page(s): 217 - 223
04/01/2011 Authors: Holguin F; Rojas M; Brown LA; Fitzpatrick AM -
Rosiglitazone attenuates alcohol-induced alveolar macrophage oxidative stress and dysfunction
Volume: 25
04/01/2011 Authors: Yeligar S; Harris F; Brown LA; Hart CM -
Glutathione oxidation is associated with airway macrophage functional impairment in children with severe asthma.
Pediatr Res Volume: 69 Page(s): 154 - 159
02/01/2011 Authors: Fitzpatrick AM; Teague WG; Burwell L; Brown MS; Brown LAS; NIH/NHLBI Severe Asthma Research Program -
Hyperoxia Decreases Junctional Proteins And Promotes Extracellular Matrix In Alveolar Epithelial Cells
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 183
01/01/2011 Authors: Vyas-Read S; Colvocoresses-Dodds J; Gauthier TW; Brown LA -
Alveolar Macrophage Phagocytic Function Is Altered In Sepsis
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 183
01/01/2011 Authors: Esper AM; Brown SD; Ward L; Brown LA; Martin GS -
Hiv Infection Decreases Alveolar Macrophage Function, Alters Zinc Bioavailability And Increases Oxidative Stress Even In Otherwise Healthy Individuals
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 183
01/01/2011 Authors: Cribbs SK; Martin GS; Brown LA; Joshi PC; Guidot DM -
Severe Sepsis Attenuates Alveolar Macrophage PPARGamma Activity
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 183
01/01/2011 Authors: Esper AM; Kleinhenz J; Ward L; Brown LA; Hart CM; Martin GS -
A SHIFT TOWARD A MORE ALTERNATIVELY ACTIVATED HUMAN ALVEOLAR MACROPHAGE: A RESPONSE TO CHRONIC ALCOHOL INGESTION
Volume: 34 Page(s): 134A - 134A
08/10/2010 Authors: Brown SD; Burnham E; Brown LAS -
Delayed neonatal lung macrophage differentiation in a mouse model of in utero ethanol exposure.
Am J Physiol Lung Cell Mol Physiol Volume: 299 Page(s): L8 - 16
07/01/2010 Authors: Gauthier TW; Ping X-D; Gabelaia L; Brown LAS -
RSV AND THE LUNG EXPOSED TO ETHANOL IN UTERO
Volume: 34 Page(s): 300A - 300A
06/01/2010 Authors: Gauthier TW; Moore M; Ping X-D; Harris FL; Brown LAS -
GLUTATHIONE ATTENUATES ALCOHOL-INDUCED PULMONARY OXIDATIVE STRESS AND RESTORES ALVEOLAR MACROPHAGE FUNCTION
Volume: 34 Page(s): 206A - 206A
06/01/2010 Authors: Yeligar SM; Harris FL; Hart CM; Brown LA -
THE EFFECTS OF ALCOHOL ABUSE ON CYTOKINE EXPRESSION IN BRONCHOALVEOLAR FLUID
Volume: 34 Page(s): 91A - 91A
06/01/2010 Authors: Brown SD; Burnham E; Brown LAS -
The molecular phenotype of severe asthma in children.
J Allergy Clin Immunol Volume: 125 Page(s): 851 - 857.e18
04/01/2010 Authors: Fitzpatrick AM; Higgins M; Holguin F; Brown LAS; Teague WG; National Institutes of Health/National Heart, Lung, and Blood Institute's Severe Asthma Research Program -
Maternal alcohol use during pregnancy causes systemic oxidation of the glutathione redox system.
Alcohol Clin Exp Res Volume: 34 Page(s): 123 - 130
01/01/2010 Authors: Gauthier TW; Kable JA; Burwell L; Coles CD; Brown LAS -
Glutathione Reduces Alcohol-induced Oxidative Stress via Downregulation of NADPH Oxidases and TGF beta(1) in Mouse Alveolar Macrophages
Volume: 49 Page(s): S203 - S203
01/01/2010 Authors: Yeligar S; Harris F; Hart M; Brown LA -
Fetal ethanol exposure and the developing alveolar macrophage
Volume: 43 Page(s): 667 - 667
12/01/2009 Authors: Gauthier TW; Ping X-D; Harris FL; Gabelaia L; Brown LAS -
Chronic ethanol treatment induces alternative activation of NR8383 macrophages
Volume: 43 Page(s): 667 - 667
12/01/2009 Authors: Brown SD; Brown LAS -
Levels of nitric oxide oxidation products are increased in the epithelial lining fluid of children with persistent asthma.
J Allergy Clin Immunol Volume: 124 Page(s): 990-6.e1-9
11/01/2009 Authors: Fitzpatrick AM; Brown LAS; Holguin F; Teague WG; National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program -
Impaired terminal differentiation of pulmonary macrophages in a Guinea pig model of chronic ethanol ingestion.
Alcohol Clin Exp Res Volume: 33 Page(s): 1782 - 1793
10/01/2009 Authors: Brown SD; Gauthier TW; Brown LAS -
N-acetylcysteine improves group B streptococcus clearance in a rat model of chronic ethanol ingestion.
Alcohol Clin Exp Res Volume: 33 Page(s): 1197 - 1201
07/01/2009 Authors: Tang SM; Gabelaia L; Gauthier TW; Brown LAS -
OXIDATIVE STRESS AND ALVEOLAR MACROPHAGE DYSFUNCTION IN THE ALCOHOLIC LUNG
Volume: 33 Page(s): 289A - 289A
06/01/2009 Authors: Guidot DM; Mehta AJ; Brown LAS; Joshi PC -
The peroxisome proliferator-activated gamma (PPAR gamma) ligand, rosiglitazone, attenuates lung barrier dysfunction following chronic alcohol ingestion
FASEB JOURNAL Volume: 23
04/01/2009 Authors: Wagner MC; Hart CM; Brown LS; Kleinhenz DJ -
Oxidative Stress In Lung Allograft Recipients with and without Graft Dysfunction
Volume: 28 Page(s): S283 - S284
02/01/2009 Authors: Naik PM; Brown LAS; Lawrence EC; Force SD; Ramirez A; Neujahr DC; Foster M; Mitchell PO; Pelaez A -
In utero ethanol exposure impairs defenses against experimental group B streptococcus in the term Guinea pig lung.
Alcohol Clin Exp Res Volume: 33 Page(s): 300 - 306
02/01/2009 Authors: Gauthier TW; Young PA; Gabelaia L; Tang SM; Ping X-D; Harris FL; Brown LAS -
Intestinal redox status of major intracellular thiols in a rat model of chronic alcohol consumption.
JPEN J Parenter Enteral Nutr Volume: 33 Page(s): 662 - 668
01/01/2009 Authors: Tian J; Brown LAS; Jones DP; Levin MS; Wang L; Rubin DC; Ziegler TR -
Airway Adipokines and Airway Oxidative Stress in Lean and Obese Controls and Asthmatics
Volume: 179
01/01/2009 Authors: Holguin F; Fitzpatrick A; Anderson A; Brown LA -
Acetaldehyde Promoted Epithelial-Mesenchymal Transition through Increased TGF-beta.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 179
01/01/2009 Authors: Mason CA; Brown LAS -
Chronic Ethanol Induced Alteration of Alveolar Macrophages and Alternative Activation of Alveolar Macrophages: A Possible Link
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 179
01/01/2009 Authors: Brown SD; Brown LAS -
Transforming Growth Factor Beta-1 (TGF beta(1)) Is Increased in the Airways of Children with Severe Asthma and Correlates with the Magnitude of Oxidant Stress.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 179
01/01/2009 Authors: Fitzpatrick AM; Teague WG; Holguin F; Brown LAS -
An Imbalance of Excessive TGF beta 1 and Decreased GMCSF in the Developing Lung Exposed to Fetal Ethanol
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 179
01/01/2009 Authors: Gauthier TW; Ping XD; Harris FL; Brown LAS -
REACTIVE OXYGEN SPECIES ARE INTEGRAL IN EPITHELIAL-MESENCHYMAL TRANSITION OF ALVEOLAR EPITHELIAL CELLS
Volume: 57 Page(s): 363 - 363
01/01/2009 Authors: Vyas-Read S; Gauthier T; Brown L -
Reactive Oxygen Species Are Integral in Alveolar Epithelial - Mesenchymal Transition.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 179
01/01/2009 Authors: Vyas-Read S; Gauthier TW; Brown LA -
Airway glutathione homeostasis is altered in children with severe asthma: evidence for oxidant stress.
J Allergy Clin Immunol Volume: 123 Page(s): 146 - 152.e8
01/01/2009 Authors: Fitzpatrick AM; Teague WG; Holguin F; Yeh M; Brown LAS; Severe Asthma Research Program -
FATTY ACID ETHYL ESTERS AS A POTENTIAL BIOMARKER OF IN-UTERO ETHANOL EXPOSURE IN PRETERM GUINEA PIG PLACENTAS
Volume: 57 Page(s): 384 - 384
01/01/2009 Authors: Mohan SS; Gauthier TW; Harris FL; Brown LS -
Highlight Commentary on "Influence of lung oxidant and antioxidant status on alveolarization: Role of light-exposed total parenteral nutrition".
Free Radic Biol Med Volume: 45 Page(s): 570 - 571
09/01/2008 Authors: Brown LAS; Gauthier TW -
Highlight Commentary on "Influence of lung oxidant and antioxidant status on alveolarization: role of light-exposed total parenteral nutrition".
Free Radic Biol Med Volume: 45 Page(s): 570 - 571
09/01/2008 Authors: Brown LAS; Gauthier TW -
Antioxidant treatment attenuates abstinence-induced exacerbation of Klebsiella pneumoniae infection
Volume: 32 Page(s): 226A - 226A
06/01/2008 Authors: Tang SM; Harris FL; Brown LAS -
Acetaldehyde promoted epithelial-mesenchymal transition through increased TGF-beta
Volume: 32 Page(s): 226A - 226A
06/01/2008 Authors: Ceceile A; Mason W; Brown LAS -
Chronic ethanol ingestion in guinea pigs impairs alveolar macrophage maturation and function
Volume: 32 Page(s): 224A - 224A
06/01/2008 Authors: Brown SD; Gauthier TW; Brown LAS -
Alveolar macrophage phagocytosis is impaired in children with poorly controlled asthma.
J Allergy Clin Immunol Volume: 121 Page(s): 1372 - 1378.e3
06/01/2008 Authors: Fitzpatrick AM; Holguin F; Teague WG; Brown LAS -
Lung lining fluid glutathione attenuates IL-13-induced asthma.
Am J Respir Cell Mol Biol Volume: 38 Page(s): 509 - 516
05/01/2008 Authors: Lowry MH; McAllister BP; Jean J-C; Brown LAS; Hughey RP; Cruikshank WW; Amar S; Lucey EC; Braun K; Johnson P -
Effect of HIV-1-related protein expression on cardiac and skeletal muscles from transgenic rats.
AIDS Res Ther Volume: 5 Page(s): 8
04/25/2008 Authors: Otis JS; Ashikhmin YI; Brown LAS; Guidot DM -
Non-invasive evaluation of pulmonary glutathione in the exhaled breath condensate of otherwise healthy alcoholics.
Respir Med Volume: 102 Page(s): 248 - 255
02/01/2008 Authors: Yeh MY; Burnham EL; Moss M; Brown LAS -
Association of body mass index (BMI) and airway adipokines in adults with and without asthma
Volume: 56 Page(s): 449 - 449
01/01/2008 Authors: Taylor BA; Rojas M; Fitzpatrick A; Brown L; Anderson A; Holguin F -
Oxidant-induced atrogin-1 and transforming growth factor-beta1 precede alcohol-related myopathy in rats.
Muscle Nerve Volume: 36 Page(s): 842 - 848
12/01/2007 Authors: Otis JS; Brown LAS; Guidot DM -
Alcohol abuse and acute lung injury: can we target therapy?
Expert Rev Respir Med Volume: 1 Page(s): 197 - 207
10/01/2007 Authors: Prout M; Martin GS; Drexler K; Brown LAS; Guidot DM -
Chronic alcoholism alters systemic and pulmonary glutathione redox status.
Am J Respir Crit Care Med Volume: 176 Page(s): 270 - 276
08/01/2007 Authors: Yeh MY; Burnham EL; Moss M; Brown LAS -
Chronic ethanol ingestion increases nitric oxide production in the lung.
Alcohol Volume: 41 Page(s): 309 - 316
08/01/2007 Authors: Polikandriotis JA; Rupnow HL; Brown LA; Hart CM -
Alveolar type II cells from ethanol-fed rats produce a fibronectin-enriched extracellular matrix that promotes monocyte activation.
Alcohol Volume: 41 Page(s): 317 - 324
08/01/2007 Authors: Brown LAS; Ritzenthaler JD; Guidot DM; Roman J -
Chronic ethanol ingestion in guinea pigs impairs alveolar macrophage maturation
Volume: 31 Page(s): 94A - 94A
06/01/2007 Authors: Brown SD; Gauthier TW; Brown LAS -
Alcohol-induced oxidative stress may stimulate the atrogin-1/TGF beta 1 pathway and initiate the onset of alcoholic myopathy
Volume: 31 Page(s): 93A - 93A
06/01/2007 Authors: Otis JS; Brown LAS; Guidot DM -
Epithelial barrier dysfunction in the alcoholic lung: Basic mechanisms and potential therapies
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH Volume: 31 Page(s): 290A - 290A
06/01/2007 Authors: Guider DM; Joshi PC; Koval MH; Eaton DC; Brown LS -
Increased glutathione availability rescues alveolar macrophage function in the rat model of chronic ethanol ingestion
Volume: 31 Page(s): 310A - 310A
06/01/2007 Authors: Brown LAS; Tang SM; Guidot DM; Gauthier TW -
In utero ethanol decreases neonatal alveolar macrophage maturation through decreased PU.1
Volume: 31 Page(s): 101A - 101A
06/01/2007 Authors: Gauthier TW; Ping X-D; Brown LAS -
Oxidative stress downregulates expression of GM-CSF receptor on the alcoholic alveolar macrophages: Role of transforming growth factor beta
Volume: 31 Page(s): 95A - 95A
06/01/2007 Authors: Joshi PC; Brown LAS; Guidot DM -
Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics.
Respir Res Volume: 8 Page(s): 32
04/16/2007 Authors: Komakula S; Khatri S; Mermis J; Savill S; Haque S; Rojas M; Brown L; Teague GW; Holguin F -
Glutathione availability modulates alveolar macrophage function in the chronic ethanol-fed rat.
Am J Physiol Lung Cell Mol Physiol Volume: 292 Page(s): L824 - L832
04/01/2007 Authors: Brown LAS; Ping X-D; Harris FL; Gauthier TW -
In vivo dysfunction of the term alveolar macrophage after in utero ethanol exposure.
Alcohol Clin Exp Res Volume: 31 Page(s): 308 - 316
02/01/2007 Authors: Ping X-D; Harris FL; Brown LAS; Gauthier TW -
Acute and chronic alcohol abuse modulate immunity.
Alcohol Clin Exp Res Volume: 30 Page(s): 1624 - 1631
09/01/2006 Authors: Brown LAS; Cook RT; Jerrells TR; Kolls JK; Nagy LE; Szabo G; Wands JR; Kovacs EJ -
Dampened GM-CSF signaling and impaired innate immune function in alveolar macrophages in the alcoholic lung
Volume: 39 Page(s): 114 - 114
06/01/2006 Authors: Guidot DM; Joshi PC; Brown LA; Eaton D-AC; Roman J -
Fetal alcohol's effect on alveolar macrophage maturation
Volume: 30 Page(s): 176A - 176A
06/01/2006 Authors: Gauthier TW; Ping XD; Gabelaia L; Brown LAS -
Chronic ethanol ingestion exacerbates redox stress and lung epithelial dysfunction in HIV-1 transgenic rats.
Volume: 30 Page(s): 67A - 67A
06/01/2006 Authors: Jacob BA; Lassiter CC; Brown LAS; Sutliff R; Guidot DM -
Procysteine supplementation and in vivo Group B Streptococcus clearance in a chronic ethanol model.
Volume: 30 Page(s): 224A - 224A
06/01/2006 Authors: Tang SM; Gabelaia L; Gauthier T; Brown LAS -
Cytokines and alcohol.
Alcohol Clin Exp Res Volume: 30 Page(s): 720 - 730
04/01/2006 Authors: Crews FT; Bechara R; Brown LA; Guidot DM; Mandrekar P; Oak S; Qin L; Szabo G; Wheeler M; Zou J -
Gut mucosal redox status in a rat model of chronic alcohol consumption
Volume: 20 Page(s): A146 - A146
03/06/2006 Authors: Tian JQ; Ziegler TR; Harris F; Jones DP; Brown LA -
Chronic ethanol ingestion increases superoxide production and NADPH oxidase expression in the lung.
Am J Respir Cell Mol Biol Volume: 34 Page(s): 314 - 319
03/01/2006 Authors: Polikandriotis JA; Rupnow HL; Elms SC; Clempus RE; Campbell DJ; Sutliff RL; Brown LAS; Guidot DM; Hart CM -
Chronic ethanol ingestion causes alveolar macrophage dysfunction: The role of peroxisome proliferator-activated receptor gamma.
Volume: 54 Page(s): S297 - S297
01/01/2006 Authors: Polikandriotis JA; Gonzalez F; Brown LA; Hart CM -
HIV-1 transgenic expression in rats impairs alveolar epithelial barrier function.
Volume: 54 Page(s): S297 - S297
01/01/2006 Authors: Lassiter CC; Joshi PC; Brown LAS; Guidot DM -
Chronic ethanol ingestion in rats decreases granulocyte-macrophage colony-stimulating factor receptor expression and downstream signaling in the alveolar macrophage (vol 175, pg 6837, 2005)
JOURNAL OF IMMUNOLOGY Volume: 175 Page(s): 8439 - 8439
12/15/2005 Authors: Joshi PC; Applewhite L; Ritzenthaler JD; Roman J; Fernandez AL; Eaton DC; Brown LAS; Guidot DM -
Chronic ethanol ingestion in rats decreases granulocyte-macrophage colony-stimulating factor receptor expression and downstream signaling in the alveolar macrophage.
J Immunol Volume: 175 Page(s): 6837 - 6845
11/15/2005 Authors: Joshi PC; Applewhite L; Ritzenthaler JD; Roman J; Fernandez AL; Eaton DC; Brown LAS; Guidot DM -
Angiotensin II mediates glutathione depletion, transforming growth factor-beta1 expression, and epithelial barrier dysfunction in the alcoholic rat lung.
Am J Physiol Lung Cell Mol Physiol Volume: 289 Page(s): L363 - L370
09/01/2005 Authors: Bechara RI; Pelaez A; Palacio A; Joshi PC; Hart CM; Brown LAS; Raynor R; Guidot DM -
Mechanical ventilation exacerbates alveolar macrophage dysfunction in the lungs of ethanol-fed rats.
Alcohol Clin Exp Res Volume: 29 Page(s): 1457 - 1465
08/01/2005 Authors: Kamat PP; Slutsky A; Zhang H; Bechara RI; Brown LAS; Garcia RC; Joshi PC; Kershaw CD; Guidot DM -
Maternal alcohol abuse and neonatal infection.
Alcohol Clin Exp Res Volume: 29 Page(s): 1035 - 1043
06/01/2005 Authors: Gauthier TW; Drews-Botsch C; Falek A; Coles C; Brown LAS -
The effects of chronic ethanol ingestion on rat alveolar macrophage expression of the granulocyte/macrophage colony-stimulating factor receptor and PU.1
Volume: 36 Page(s): 130 - 130
06/01/2005 Authors: Joshi PC; Brown LAS; Guidot DM -
Impaired cytokine regulation renders the alcoholic lung susceptible to injury from both aberrant immune activation and immune suppression
Volume: 29 Page(s): 193A - 193A
05/01/2005 Authors: Guidot D; Bechara R; Brown L -
Chronic ethanol ingestion alters superoxide production in the lung by a renin-angiotensin system-dependent pathway.
Volume: 29 Page(s): 52A - 52A
05/01/2005 Authors: Polikandriotie JA; Rupnow HL; Brown LAS; Guidot DM; Hart CM -
In utero ethanol delays fetal alveolar macrophage maturation
Volume: 29 Page(s): 87A - 87A
05/01/2005 Authors: Gauthier TW; Ping XD; Harris FL; Brown LAS -
Ethanol stimulates the expression of fibronectin in lung fibroblasts via kinase-dependent signals that activate CREB.
Am J Physiol Lung Cell Mol Physiol Volume: 288 Page(s): L975 - L987
05/01/2005 Authors: Roman J; Ritzenthaler JD; Bechara R; Brown LA; Guidot D -
Glutathione supplements restore phagocytosis in ethanol-impaired rat alveolar macrophages
Volume: 29 Page(s): 125A - 125A
05/01/2005 Authors: Brown LAS; Harris FL; Ping XD; Gauthier TW -
The effects of chronic ethanol ingestion on alveolar macrophage membrane expression of the granulocyteimacrophage colony-stimulating factor (GM-CSF) receptor.
Volume: 29 Page(s): 139A - 139A
05/01/2005 Authors: Femandez AL; Joshi PC; Brown LAS; Guldot DM -
Modulation of connexin expression in rat lung by ethanol consumption
Volume: 19 Page(s): A1294 - A1294
03/07/2005 Authors: Wheaton AG; Brown LS -
The renin angiotensin system mediates chronic ethanol-induced increases in superoxide production and NADPH oxidase expression in the lung.
JOURNAL OF INVESTIGATIVE MEDICINE Volume: 53 Page(s): S287 - S287
01/01/2005 Authors: Polikandriots JA; Rupnow HL; Sutliff RL; Brown LS; Guidot DM; Hart CM -
Fetal alcohol exposure impairs alveolar macrophage function via decreased glutathione availability.
Pediatr Res Volume: 57 Page(s): 76 - 81
01/01/2005 Authors: Gauthier TW; Ping X-D; Harris FL; Wong M; Elbahesh H; Brown LAS -
Ethanol consumption increases systemic oxidative stress in the gravid guinea
JOURNAL OF INVESTIGATIVE MEDICINE Volume: 53 Page(s): S325 - S325
01/01/2005 Authors: Young P; Ping XD; Brown LAS; Gauthier TW -
Influenza virus inhibits ENaC and lung fluid clearance.
Am J Physiol Lung Cell Mol Physiol Volume: 287 Page(s): L366 - L373
08/01/2004 Authors: Chen X-J; Seth S; Yue G; Kamat P; Compans RW; Guidot D; Brown LA; Eaton DC; Jain L -
Transforming growth factor beta1 expression and activation is increased in the alcoholic rat lung.
Am J Respir Crit Care Med Volume: 170 Page(s): 188 - 194
07/15/2004 Authors: Bechara RI; Brown LAS; Roman J; Joshi PC; Guidot DM -
Chronic ethanol ingestion and the risk of acute lung injury: a role for glutathione availability?
Volume: 33 Page(s): 191 - 197
07/01/2004 Authors: Brown LAS; Harris FL; Ping X-D; Gauthier TW -
Is maternal alcohol use a risk factor for early-onset sepsis in premature newborns?
Alcohol Volume: 33 Page(s): 139 - 145
06/01/2004 Authors: Gauthier TW; Manar MH; Brown LAS -
Granulocyte/macrophage colony-stimulating factor (GM-CSF) restores bacterial phagocytosis in alveolar macrophages from ethenol-fed rats.
Volume: 28 Page(s): 37A - 37A
05/01/2004 Authors: Kamat PP; Brown LAS; Garcia R; Joshi P; Guidot DM -
Alveolar macrophage dysfunction in the alcoholic rat lung is associated with impaired granulocyte/macrophage colony-stimulating factor (GM-CSF) signaling.
Volume: 28 Page(s): 129A - 129A
05/01/2004 Authors: Applewhite L; Brown LAS; Garcia R; Joshi PC; Guidot DM -
Fetal ethanol's effect on in vivo term alveolar macroprage phagocytosis - A confocal analysis
Volume: 28 Page(s): 85A - 85A
05/01/2004 Authors: Gauthier TW; Ping XD; Harris FL; Brown LAS -
Ethanol induces alveolar type II cells to deposit a matrix that promotes monocyte activation
Volume: 28 Page(s): 123A - 123A
05/01/2004 Authors: Roman J; Ritzenthaler JD; Guidot DM; Brown LAS -
Ethanol exposure increases pro-inflammatory cytokines in the amniotic fluid and the fetal airway
Volume: 55 Page(s): 489A - 489A
04/01/2004 Authors: Gauthier HW; Du Ping X; Brown LAS -
Elevated plasma and lung endothelial selectin levels in patients with acute respiratory distress syndrome and a history of chronic alcohol abuse.
Crit Care Med Volume: 32 Page(s): 675 - 679
03/01/2004 Authors: Burnham EL; Moss M; Harris F; Brown LAS -
Granulocyte/macrophage colony-stimulating factor treatment improves alveolar epithelial barrier function in alcoholic rat lung.
Am J Physiol Lung Cell Mol Physiol Volume: 286 Page(s): L106 - L111
01/01/2004 Authors: Pelaez A; Bechara RI; Joshi PC; Brown LAS; Guidot DM -
Chronic ethanol ingestion impairs granulocyte-macrhophage colony stimulating factor (GM-CSF) signaling in the rat lung.
Volume: 52 Page(s): S317 - S318
01/01/2004 Authors: Pelaez A; Brown LS; Joshi PC; Applewhite L; Bechara RI; Guidot DM -
Effects of chronic ethanol ingestion on NADPH oxidase expression in the lung in vivo.
Volume: 52 Page(s): S317 - S317
01/01/2004 Authors: Rupnow HL; Clempus RE; Greindling KK; Brown LS; Guidot DM; Hart CM -
Chronic ethanol ingestion impairs bacterial phagocytosis by alveolar macrophages during mechanical ventilation in a rat model.
Volume: 52 Page(s): S317 - S317
01/01/2004 Authors: Kamat PP; Bechara RI; Brown LS; Guidot DM -
Association of glutathione-S-transferase-P1 (GST-P1) polymorphisms with bronchopulmonary dysplasia.
J Perinatol Volume: 24 Page(s): 30 - 35
01/01/2004 Authors: Manar MH; Brown MR; Gauthier TW; Brown LAS -
Brain nitric oxide synthase levels increase in response to antenatal ethanol exposure.
Alcohol Alcohol Volume: 39 Page(s): 101 - 105
01/01/2004 Authors: Dizon MLV; Brown LA; Black SM -
An assessment of antecedent events influencing noncompliance in an outpatient clinic.
J Appl Behav Anal Volume: 37 Page(s): 145 - 157
01/01/2004 Authors: Call NA; Wacker DP; Ringdahl JE; Cooper-Brown LJ; Boeiter EW -
Effects of chronic alcohol abuse on alveolar epithelial barrier function and glutathione homeostasis.
Alcohol Clin Exp Res Volume: 27 Page(s): 1167 - 1172
07/01/2003 Authors: Burnham EL; Brown LAS; Halls L; Moss M -
Chronic ethanol ingestion increases expression of the angiotensin II type 2 (AT2) receptor and enhances tumor necrosis factor-alpha- and angiotensin II-induced cytotoxicity via AT2 signaling in rat alveolar epithelial cells.
Alcohol Clin Exp Res Volume: 27 Page(s): 1006 - 1014
06/01/2003 Authors: Bechara RI; Brown LAS; Eaton DC; Roman J; Guidot DM -
In utero alcohol exposure increases fetal type II epithelial cell oxidative stress and cellular apoptosis in the developing lung
Volume: 53 Page(s): 554A - 554A
04/01/2003 Authors: Brown LAS; Ping XD; Harris FL; Gauthier TW -
Increased hospital stay for premature newborns - The hidden effects of maternal alcohol use
Volume: 53 Page(s): 476A - 477A
04/01/2003 Authors: Gauthier TW; Manar MH; Carson DP; Brown LAS; Sola A -
Is fetal alcohol exposure a risk factor for early onset sepsis in the very low birth weight infant?
Volume: 53 Page(s): 425A - 425A
04/01/2003 Authors: Gauthier TW; Manar MH; Carson DP; Sola A; Brown LAS -
Antenatal maternal alcohol use as a risk factor for severe intraventricular hemorrhage and brain malformations in preterm infants
Volume: 53 Page(s): 425A - 425A
04/01/2003 Authors: Manar M; Gauthier T; Carson D; Rogido M; Brown LA; Sola A -
Effects of in vitro ethanol exposure on nitric oxide synthase expression and activity in porcine pulmonary artery endothelial cells
Volume: 17 Page(s): A411 - A411
03/14/2003 Authors: Rupnow HL; Brown LAS; Hart CM -
Effects of in vitro ethanol exposure on nitric oxide synthase expression and activity in porcine pulmonary artery endothellil cells.
Volume: 51 Page(s): S446 - S446
03/01/2003 Authors: Rupnow HL; Brown LAS; Hart CM -
Chronic ethanol ingestion impairs alveolar macrophage immune function in vitro,and cytokine release during mechanical ventilation ex vivo.
Volume: 51 Page(s): S279 - S279
02/01/2003 Authors: Kamat PP; Brown LS; Slutsky A; Guidot DM; Bechara RI -
Effects of in vitro ethanol exposure on nitric oxide synthase expression and activity in porcine pulmonary artery endothelial cells.
Volume: 51 Page(s): S269 - S269
02/01/2003 Authors: Rupnow HL; Brown LAS; Hart CM -
Chronic ethanol ingestion impairs alveolar macrophage immune function in vitro, and cytokine release during mechanical ventilation ex vivo.
Volume: 51 Page(s): S293 - S294
02/01/2003 Authors: Kamat PP; Brown LS; Slutsky A; Guidot DM; Bechara RI -
Chronic ethanol ingestion, via angiotensin II, causes oxidative stress and induces expression of transforming growth factor beta in the rat lung: A proposed mechanism for alcohol-mediated lung injury.
Volume: 51 Page(s): S294 - S294
02/01/2003 Authors: Bechara RI; Brown LS; Guidot DM -
Effects of chronic hepatic dysfunction on pulmonary glutathione homeostasis.
Alcohol Clin Exp Res Volume: 26 Page(s): 1840 - 1845
12/01/2002 Authors: Foreman MG; Hoor TT; Brown LAS; Moss M -
Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia.
Am J Physiol Lung Cell Mol Physiol Volume: 283 Page(s): L766 - L776
10/01/2002 Authors: Jean JC; Liu Y; Brown LA; Marc RE; Klings E; Joyce-Brady M -
Glutathione replacement preserves the functional surfactant phospholipid pool size and decreases sepsis-mediated lung dysfunction in ethanol-fed rats.
Alcohol Clin Exp Res Volume: 26 Page(s): 1245 - 1251
08/01/2002 Authors: Velasquez A; Bechara RI; Lewis JF; Malloy J; McCaig L; Brown LAS; Guidot DM -
Maternal alcohol use and neonatal infection.
AMERICAN JOURNAL OF EPIDEMIOLOGY Volume: 155 Page(s): s98 - s98
06/01/2002 Authors: Drews CD; Gauthier TW; Brown LAS -
Comparison of mechanisms of anemia in mice with sickle cell disease and beta-thalassemia: peripheral destruction, ineffective erythropoiesis, and phospholipid scramblase-mediated phosphatidylserine exposure.
Exp Hematol Volume: 30 Page(s): 394 - 402
05/01/2002 Authors: Kean LS; Brown LE; Nichols JW; Mohandas N; Archer DR; Hsu LL -
Genetic polymorphisms of antioxidant enzymes in chronic lung disease
PEDIATRIC RESEARCH Volume: 51 Page(s): 350A - 350A
04/01/2002 Authors: Manar MH; Brown M; Gauthier T; Simon N; Lesnick B; Brown L -
Apoptosis contributes to premature alveolar macrophage dysfunction - A need for glutathione?
PEDIATRIC RESEARCH Volume: 51 Page(s): 327A - 327A
04/01/2002 Authors: Gauthier TW; Elbahesh H; Ping XD; Harris FL; Brown LAS -
Chronic maternal ethanol ingestion decreased lung glutathione availability and altered pulmonary function
PEDIATRIC RESEARCH Volume: 51 Page(s): 471A - 471A
04/01/2002 Authors: Brown LAS; Gauthier TW; Harris FL -
Chronic ethanol (ETOH) ingestion decreases mitochondrial function of alveolar type II cells via glutathione (GSH) availability.
FASEB JOURNAL Volume: 16 Page(s): A413 - A413
03/20/2002 Authors: Brown LAS; Harris FL -
Hepatitis C knowledge base of providers caring for HIV positive communities of color
CLINICAL INFECTIOUS DISEASES Volume: 33 Page(s): 1242 - 1242
10/01/2001 Authors: Smith CA; Johnson M; Brown LS -
Chronic ethanol ingestion potentiates TNF-alpha-mediated oxidative stress and apoptosis in rat type II cells.
Am J Physiol Lung Cell Mol Physiol Volume: 281 Page(s): L377 - L386
08/01/2001 Authors: Brown LA; Harris FL; Guidot DM -
Effect of chronic ethanol ingestion on alveolar type II cell: glutathione and inflammatory mediator-induced apoptosis.
Alcohol Clin Exp Res Volume: 25 Page(s): 1078 - 1085
07/01/2001 Authors: Brown LA; Harris FL; Bechara R; Guidot DM -
TGF-beta is a critical mediator of acute lung injury.
J Clin Invest Volume: 107 Page(s): 1537 - 1544
06/01/2001 Authors: Pittet JF; Griffiths MJ; Geiser T; Kaminski N; Dalton SL; Huang X; Brown LA; Gotwals PJ; Koteliansky VE; Matthay MA -
Expression of highly selective sodium channels in alveolar type II cells is determined by culture conditions.
Am J Physiol Lung Cell Mol Physiol Volume: 280 Page(s): L646 - L658
04/01/2001 Authors: Jain L; Chen XJ; Ramosevac S; Brown LA; Eaton DC -
Chronic ethanol ingestion decreases glutathione and increases protein in the epithelial lining fluid of rats.
FASEB JOURNAL Volume: 15 Page(s): A859 - A859
03/08/2001 Authors: Brown LAS; Moss M; Guidot DM -
S-nitrosoglutathione inhibits TNF-alpha-induced NFkappaB activation in neutrophils.
Inflamm Res Volume: 50 Page(s): 89 - 95
02/01/2001 Authors: Fortenberry JD; Owens ML; Chen NX; Brown LA -
Neutrophils induce apoptosis of lung epithelial cells via release of soluble Fas ligand.
Am J Physiol Lung Cell Mol Physiol Volume: 280 Page(s): L298 - L305
02/01/2001 Authors: Serrao KL; Fortenberry JD; Owens ML; Harris FL; Brown LA -
Ethanol ingestion, via glutathione depletion, impairs alveolar epithelial function and renders the lung susceptible to acute injury during oxidative stress
Volume: 336 Page(s): 174 - 185
01/01/2001 Authors: Guidot DM; Moss M; Brown LAS -
A reply.
Clin Radiol Volume: 55 Page(s): 986
12/01/2000 Authors: Curtis J; Lewis-Jones H -
Adenovirus-mediated transfer of an Na+/K+-ATPase beta1 subunit gene improves alveolar fluid clearance and survival in hyperoxic rats.
Hum Gene Ther Volume: 11 Page(s): 2231 - 2242
11/01/2000 Authors: Factor P; Dumasius V; Saldias F; Brown LA; Sznajder JI -
Mitochondrial glutathione replacement restores surfactant synthesis and secretion in alveolar epithelial cells of ethanol-fed rats.
Alcohol Clin Exp Res Volume: 24 Page(s): 1070 - 1076
07/01/2000 Authors: Guidot DM; Brown LA -
Ethanol ingestion via glutathione depletion impairs alveolar epithelial barrier function in rats.
Am J Physiol Lung Cell Mol Physiol Volume: 279 Page(s): L127 - L135
07/01/2000 Authors: Guidot DM; Modelska K; Lois M; Jain L; Moss IM; Pittet JF; Brown LA -
Glutathione augments premature alveolar macrophage phagocytosis
PEDIATRIC RESEARCH Volume: 47 Page(s): 359A - 359A
04/01/2000 Authors: Gauthier TW; Harris FL; Brown LAS -
The effects of chronic alcohol abuse on pulmonary glutathione homeostasis.
Am J Respir Crit Care Med Volume: 161 Page(s): 414 - 419
02/01/2000 Authors: Moss M; Guidot DM; Wong-Lambertina M; Ten Hoor T; Perez RL; Brown LA -
Ethanol ingestion, via mitochondrial depletion of glutathione, renders the alveolar epithelium susceptible to apoptosis.
JOURNAL OF INVESTIGATIVE MEDICINE Volume: 48 Page(s): 154A - 154A
01/01/2000 Authors: Bechara R; Velasquez A; Brown LA; Guidot DM -
Chronic ethanol ingestion alters surfactant composition and increases acute lung injury in septic rats.
JOURNAL OF INVESTIGATIVE MEDICINE Volume: 48 Page(s): 173A - 173A
01/01/2000 Authors: Velasquez A; Brown LA; Lewis JF; Malloy J; McCaig LA; Guidot DM -
Ethanol ingestion alters extracellular matrix remodeling in rat lungs.
JOURNAL OF INVESTIGATIVE MEDICINE Volume: 48 Page(s): 128A - 128A
01/01/2000 Authors: Bechara R; Velasquez A; Lois M; Brown LA; Roman J; Guidot DM -
Adjunct glutathione reverses endothelial damage from peroxynitrite, the by-product of nitric oxide degradation, in crystalloid cardioplegia
CIRCULATION Volume: 100 Page(s): 227 - 227
11/02/1999 Authors: Nakamura M; Thourani VH; Ronson RS; Velez D; Ma XL; Brown LAS; Guyton RA; Vinten-Johansen J -
Ethanol ingestion increases activation of matrix metalloproteinases in rat lungs during acute endotoxemia.
Am J Respir Crit Care Med Volume: 160 Page(s): 1354 - 1360
10/01/1999 Authors: Lois M; Brown LA; Moss IM; Roman J; Guidot DM -
Effects of exogenous nitric oxide and hyperoxia on lung fibroblast viability and DNA fragmentation.
Biochem Biophys Res Commun Volume: 262 Page(s): 685 - 691
09/07/1999 Authors: Raghuram N; Fortenberry JD; Owens ML; Brown LA -
Ethanol ingestion impairs alveolar epithelial glutathione homeostasis and function, and predisposes to endotoxin-mediated acute lung injury.
Chest Volume: 116 Page(s): 82S
07/01/1999 Authors: Guidot D; Moss M; Holguin F; Lois M; Brown L -
Transgenic HbS mouse neutrophils in increased susceptibility to acute lung injury: implications for sickle acute chest syndrome.
Chest Volume: 116 Page(s): 92S
07/01/1999 Authors: Hsu L; McDermott T; Brown L; Aguayo SM -
Solubility of various forms of strontium titanate in lungs: in vitro and in vivo studies.
Health Phys Volume: 76 Page(s): 628 - 634
06/01/1999 Authors: Anderson J; Kahn B; LaBone T; Brown L; Harris F -
Inhibition of beta-adrenergic-dependent alveolar epithelial clearance by oxidant mechanisms after hemorrhagic shock.
Am J Physiol Volume: 276 Page(s): L844 - L857
05/01/1999 Authors: Modelska K; Matthay MA; Brown LA; Deutch E; Lu LN; Pittet JF -
Ethanol ingestion impairs alveolar epithelial barrier function in rats.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 159 Page(s): A594 - A594
03/01/1999 Authors: Lois M; Moss IM; Modelska K; Brown LS; Jain L; Pittet JF; Guidot DM -
S-nitrosoglutathione enhances neutrophil DNA fragmentation and cell death.
Am J Physiol Volume: 276 Page(s): L435 - L442
03/01/1999 Authors: Fortenberry JD; Owens ML; Brown LA -
The ontogeny of lung injury: An in vitro fetal pulmonary bilayer.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 159 Page(s): A177 - A177
03/01/1999 Authors: Gauthier TW; Harris FL; Brown LAS -
Maternal ethanol ingestion decreases fetal lung glutathione and surfactant homeostasis.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 159 Page(s): A153 - A153
03/01/1999 Authors: Brown LAS; Harris FL; Guidot DM; Gauthier TW -
Glutathione levels are decreased in the alveolar lining fluid of the lung from patients with cirrhosis.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 159 Page(s): A376 - A376
03/01/1999 Authors: TenHoor TL; Brown LAS; Guidot DM; Moss M -
Beta-adrenergic agonists stimulate lung epithelial sodium transport via a camp-mediated activation of amiloride-sensitive cation channels.
PEDIATRICS Volume: 102 Page(s): 755 - 755
09/01/1998 Authors: Jain L; Chen XJ; Brown LA; Eaton DC -
Neutrophils induce apoptosis of alveolar epithelial cells via Fas/Fas ligand interaction.
PEDIATRICS Volume: 102 Page(s): 702 - 702
09/01/1998 Authors: Serrao K; Fortenberry JD; Brown LS -
Glutathione measurement in human plasma. Evaluation of sample collection, storage and derivatization conditions for analysis of dansyl derivatives by HPLC.
Clin Chim Acta Volume: 275 Page(s): 175 - 184
07/28/1998 Authors: Jones DP; Carlson JL; Samiec PS; Sternberg P; Mody VC; Reed RL; Brown LA -
Nitric oxide (NO) and inducible nitric oxide synthase (iNOS) are produced after Helicobacter pylori infection of cultured epithelial cells in vitro.
Volume: 114 Page(s): A986 - A986
04/15/1998 Authors: Gold BD; Khanna B; Newman G; Owens M; Harris FL; Smoot D; Brown L -
Nitric oxide inhibits lung sodium transport through a cGMP-mediated inhibition of epithelial cation channels.
Am J Physiol Volume: 274 Page(s): L475 - L484
04/01/1998 Authors: Jain L; Chen XJ; Brown LA; Eaton DC -
Exogenous nitric oxide enhances neutrophil cell death and DNA fragmentation.
Am J Respir Cell Mol Biol Volume: 18 Page(s): 421 - 428
03/01/1998 Authors: Fortenberry JD; Owens ML; Brown MR; Atkinson D; Brown LA -
Chronic ethanol ingestion impairs alveolar type II cell glutathione homeostasis and function and predisposes to endotoxin-mediated acute edematous lung injury in rats.
J Clin Invest Volume: 101 Page(s): 761 - 768
02/15/1998 Authors: Holguin F; Moss I; Brown LA; Guidot DM -
Ethanol ingestion decreases alveolar type II cell mitochondrial glutathione levels and impairs surfactant secretion and viability in vitro: A proposed mechanism by which chronic alcoholism predisposes to acute lung injury.
JOURNAL OF INVESTIGATIVE MEDICINE Volume: 46 Page(s): 17A - 17A
01/01/1998 Authors: Holguin F; Moss IM; Brown LS; Guidot DM -
Transgenic HbS mouse neutrophils in increased susceptibility to acute lung injury - Implications for sickle acute chest syndrome.
BLOOD Volume: 90 Page(s): 543 - 543
11/15/1997 Authors: Hsu LL; McDermott T; Brown LAS; Aguayo SM -
Ascorbate deficiency and oxidative stress in the alveolar type II cell.
Am J Physiol Volume: 273 Page(s): L782 - L788
10/01/1997 Authors: Brown LA; Harris FL; Jones DP -
Ascorbate deficiency impairs sodium transport by distal lung epithelia
Volume: 100 Page(s): 496 - 496
09/01/1997 Authors: Jain L; Chen XJ; Brown LA; Eaton D -
Effects of exogenous nitric oxide on neutrophil oxidative function and viability.
Am J Respir Cell Mol Biol Volume: 16 Page(s): 407 - 412
04/01/1997 Authors: Daher AH; Fortenberry JD; Owens ML; Brown LA -
Effect of oleic acid on transgenic mice expressing human HbS - Toward an animal model for sickle acute chest syndrome
BLOOD Volume: 88 Page(s): 1973 - 1973
11/15/1996 Authors: Hsu LL; Dillehay D; Brown LAS; Cargile RD; Asakura T; Aguayo SM -
Exogenous nitric oxide (NO) enhances apoptotic neutrophil cell death.
PEDIATRIC RESEARCH Volume: 39 Page(s): 266 - 266
04/01/1996 Authors: Fortenberry JD; Owens M; Atkinson D; Brown LA -
Albuterol treatment blocks exercise-induced retention of respirable H2O2 and bronchospasm in children with asthma.
PEDIATRIC RESEARCH Volume: 39 Page(s): 2330 - 2330
04/01/1996 Authors: Teague WG; Oakman J; Owens M; Brown LAS -
Glutathione supplements protect preterm rabbits from oxidative lung injury.
Am J Physiol Volume: 270 Page(s): L446 - L451
03/01/1996 Authors: Brown LA; Perez JA; Harris FL; Clark RH -
Variability in glutathione-dependent detoxication in vivo and its relevance to detoxication of chemical mixtures.
Toxicology Volume: 105 Page(s): 267 - 274
12/28/1995 Authors: Jones DP; Brown LA; Sternberg P -
Pulmonary alveolar proteinosis in SCID mice.
Am J Respir Cell Mol Biol Volume: 13 Page(s): 297 - 306
09/01/1995 Authors: Jennings VM; Dillehay DL; Webb SK; Brown LA -
GLUTATHIONE MEASUREMENTS IN TRACHEAL ASPIRATES OF PREMATURE NEONATES
PEDIATRIC RESEARCH Volume: 37 Page(s): A326 - A326
04/01/1995 Authors: BARRIOS F; BROWN LA; CLARK RH -
EFFECTS OF NITRIC-OXIDE (NO) AND OXYGEN (O2) ON GLUTATHIONE (GSH) LEVELS IN NEWBORN RABBITS
PEDIATRIC RESEARCH Volume: 37 Page(s): A345 - A345
04/01/1995 Authors: PEREZ JA; CLARK RH; BROWN LA -
EFFECTS OF NITRIC-OXIDE (NO) EXPOSURE ON POLYMORPHONUCLEAR LEUKOCYTE (PMN) OXIDATIVE FUNCTION AND APOPTOTIC CELL-DEATH
PEDIATRIC RESEARCH Volume: 37 Page(s): A43 - A43
04/01/1995 Authors: DAHER AH; FORTENBERRY JD; OWENS ML; BROWN LA -
LUNG LINING FLUID GLUTATHIONE (GSH) REDOX BALANCE SHIFTS FROM THE REDUCED TO THE OXIDIZED STATE IN CHILDREN WITH UNSTABLE ASTHMA
PEDIATRIC RESEARCH Volume: 37 Page(s): A396 - A396
04/01/1995 Authors: TEAGUE WG; STOVROFF MA; HARSCH AD; LESNICK BL; BROWN LAS -
PROTECTION AGAINST LUNG TYPE-II HYPEROXIC CELL-DAMAGE BY DIETARY INDUCTION OF DETOXIFICATION ENZYMES
FASEB JOURNAL Volume: 9 Page(s): A971 - A971
03/10/1995 Authors: GRODZICKA DA; BROWN LAS; JONES DP; DELONG MJ -
REDUCED ASCORBATE (ASC) AVAILABILITY RETARDS PROGRESSION OF TYPE-II TO TYPE-I CELLS
FASEB JOURNAL Volume: 9 Page(s): A860 - A860
03/10/1995 Authors: PATTON SE; BROWN LAS; JONES DP -
PULMONARY ALVEOLAR PROTEINOSIS (PAP) IN SCID MICE
FASEB JOURNAL Volume: 9 Page(s): A968 - A968
03/10/1995 Authors: JENNINGS VM; DILLEHAY DL; WEBB SK; BROWN LAS -
Glutathione transport by type II cells in perfused rat lung.
Am J Physiol Volume: 267 Page(s): L447 - L455
10/01/1994 Authors: Bai C; Brown LA; Jones DP -
EFFECT OF NITRIC-OXIDE (NO) AND OXYGEN (O2) ON LUNG-MECHANICS IN NEWBORN RABBITS
PEDIATRIC RESEARCH Volume: 35 Page(s): A348 - A348
04/01/1994 Authors: PEREZ JA; BROWN LA; CLARK RH -
Glutathione protects signal transduction in type II cells under oxidant stress.
Am J Physiol Volume: 266 Page(s): L172 - L177
02/01/1994 Authors: Brown LA -
ASCORBATE DEPENDENT PROTECTION OF TYPE-II CELLS AGAINST OXIDATIVE INJURY
FASEB JOURNAL Volume: 7 Page(s): A218 - A218
02/19/1993 Authors: BROWN LAS; KIM Y; JONES DP; EDMUNDSON DE -
Stimulation of phosphatidylcholine hydrolysis in type II alveolar epithelial cells.
Am J Physiol Volume: 263 Page(s): L42 - L50
07/01/1992 Authors: Dubrovin LC; Brown LA -
Glutathione protection in alveolar type II cells from fetal and neonatal rabbits.
Am J Physiol Volume: 262 Page(s): L305 - L312
03/01/1992 Authors: Brown LA; Bai C; Jones DP -
PREFERENTIAL UPTAKE OF A FLUORESCENT GLUTATHIONE S-CONJUGATE BY ALVEOLAR TYPE-II CELLS IN THE ISOLATED PERFUSED RAT LUNG
FASEB JOURNAL Volume: 5 Page(s): A1489 - A1489
03/19/1991 Authors: BAI C; BROWN LA; JONES DP -
Influence of streptozotocin-induced diabetes on adenylate cyclase activity in cultured type II pneumocytes.
Am J Respir Cell Mol Biol Volume: 4 Page(s): 108 - 114
02/01/1991 Authors: Brown LA -
Vasopressin signal transduction in rat type II pneumocytes.
Am J Physiol Volume: 258 Page(s): L301 - L307
06/01/1990 Authors: Brown LA; Chen M -
Histamine stimulation of surfactant secretion from rat type II pneumocytes.
Am J Physiol Volume: 258 Page(s): L195 - L200
04/01/1990 Authors: Chen M; Brown LA -
Stimulation of surfactant secretion by vasopressin in primary cultures of adult rat type II pneumocytes.
Biochim Biophys Acta Volume: 1001 Page(s): 76 - 81
01/23/1989 Authors: Brown LA; Wood LH -
Sex education and AIDS education in the schools: what states and large school districts are doing.
Fam Plann Perspect Volume: 21 Page(s): 56 - 64
01/01/1989 Authors: Kenney AM; Guardado S; Brown L -
PHENOBARBITAL (PB) AUGMENTS BRAIN MITOCHONDRIAL BILIRUBIN OXIDASE (BO) ACTIVITY DURING HYPOXIA IN SPRAGUE-DAWLEY RATS
PEDIATRIC RESEARCH Volume: 21 Page(s): A355 - A355
04/01/1987 Authors: BURGESS GH; BROWN LAS -
PHENOBARBITAL AND HYPOXIA AUGMENT HEPATIC-MICROSOMAL BILIRUBIN (B) UDP-GLUCURONYLTRANSFERASE (UDPGT) ACTIVITY IN SPRAGUE-DAWLEY RATS
PEDIATRIC RESEARCH Volume: 21 Page(s): A355 - A355
04/01/1987 Authors: BURGESS GH; BROWN LAS -
GLUTATHIONE PROTECTION AGAINST PULMONARY OXIDATIVE INJURY
FEDERATION PROCEEDINGS Volume: 46 Page(s): 666 - 666
03/01/1987 Authors: BROWN LAS; CORP CC; WOOD LH; BARNWELL K; JONES DP -
Protection against paraquat-induced injury by exogenous GSH in pulmonary alveolar type II cells.
Biochem Pharmacol Volume: 35 Page(s): 4537 - 4542
12/15/1986 Authors: Hagen TM; Brown LA; Jones DP -
Altered phospholipid secretion in type II pneumocytes isolated from streptozotocin-diabetic rats.
Biochim Biophys Acta Volume: 878 Page(s): 258 - 265
09/12/1986 Authors: Brown LA; Longmore WJ -
ADENYLATE-CYCLASE ACTIVITY FROM CULTURED TYPE-II CELLS OF STREPTOZOTOCIN DIABETIC RAT LUNGS
AMERICAN REVIEW OF RESPIRATORY DISEASE Volume: 133 Page(s): A293 - A293
04/01/1986 Authors: BROWN LS -
GLUTATHIONE UPTAKE BY RAT ALVEOLAR TYPE-II CELLS PROTECTS AGAINST INJURY DUE TO PARAQUAT
FEDERATION PROCEEDINGS Volume: 45 Page(s): 216 - 216
03/01/1986 Authors: JONES DP; HAGEN TM; BROWN LS -
Role of microtubules in surfactant secretion.
J Appl Physiol (1985) Volume: 58 Page(s): 1866 - 1873
06/01/1985 Authors: Brown LA; Pasquale SM; Longmore WJ -
HYPOXIA, LUNG GROWTH AND THE SURFACTANT SYSTEM DURING ALVEOLARIZATION
PEDIATRIC RESEARCH Volume: 19 Page(s): A151 - A151
01/01/1985 Authors: BUCHTER D; FRANKE K; BROWN L; BRUMLEY G -
LUNG SURFACTANT PHOSPHATIDYLCHOLINE RELEASE FROM ADULT ALVEOLAR TYPE-II CELLS UNDER HYPOXIC CONDITIONS
Volume: 44 Page(s): 1022 - 1022
01/01/1985 Authors: BROWN LS; FRANKE K -
Effect of nutritional status on the lung surfactant system: food deprivation and caloric restriction.
Exp Lung Res Volume: 6 Page(s): 133 - 147
01/01/1984 Authors: Brown LA; Bliss AS; Longmore WJ -
ALTERATION OF RAT LUNG SURFACTANT SYSTEM BY ESSENTIAL FATTY-ACID DEFICIENCY
FEDERATION PROCEEDINGS Volume: 42 Page(s): 2228 - 2228
01/01/1983 Authors: BROWN LS; BLISS AS; LONGMORE WJ -
EFFECTS OF BETA-ADRENERGIC AGENTS ON TUBULIN POOLS IN THE ISOLATED PERFUSED RAT LUNG
Volume: 41 Page(s): 1423 - 1423
01/01/1982 Authors: BROWN LS; LONGMORE WJ -
Adrenergic and cholinergic regulation of lung surfactant secretion in the isolated perfused rat lung and in the alveolar type II cell in culture.
J Biol Chem Volume: 256 Page(s): 66 - 72
01/10/1981 Authors: Brown LA; Longmore WJ -
EFFECTS OF ANTI-MICROTUBULAR AND ANTI-MICROFILAMENT AGENTS IN ALVEOLAR TYPE-II CELLS
FEDERATION PROCEEDINGS Volume: 40 Page(s): 407 - 407
01/01/1981 Authors: BROWN LS; LONGMORE WJ -
LUNG SURFACTANT PHOSPHATIDYLCHOLINE RELEASE AND CYCLIC-NUCLEOTIDE LEVELS IN ALVEOLAR TYPE-II CELLS
Volume: 39 Page(s): 2188 - 2188
01/01/1980 Authors: BROWN LS; LONGMORE WJ -
PILOCARPINE STIMULATION OF LUNG SURFACTANT PHOSPHATIDYLCHOLINE PRODUCTION
Volume: 38 Page(s): 235 - 235
01/01/1979 Authors: BROWN LS; LONGMORE WJ