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Profile

Leon Bernal-Mizrachi MD

  • Department of Hematology and Medical Oncology
    Professor
  • (404) 778-1670
  • lbernal@emory.edu
Head shot of Leon Bernal-Mizrachi

Academic Appointment

  • Professor, Department of Hematology and Medical Oncology, Emory University School of Medicine

Education

Degrees

  • Medical Degree from Universidad del Valle School of Medicine
  • BS from Colegio de Santa Librada

Research

Publications

  • Transposon DNA sequences facilitate the tissue-specific gene transfer of circulating tumor DNA between human cells.
    Nucleic Acids Res Volume: 52 Page(s): 7539 - 7555
    07/22/2024 Authors: Cinar M; Martinez-Medina L; Puvvula PK; Arakelyan A; Vardarajan BN; Anthony N; Nagaraju GP; Park D; Feng L; Sheff F
  • The Lymphoma Epidemiology of Outcomes cohort study: Design, baseline characteristics, and early outcomes.
    Am J Hematol Volume: 99 Page(s): 408 - 421
    03/01/2024 Authors: Cerhan JR; Maurer MJ; Link BK; Feldman AL; Habermann TM; Jaye DL; Burack WR; McDonnell TJ; Vega F; Chapman JR
  • Addressing the disparities: the approach to the African American patient with multiple myeloma.
    Blood Cancer J Volume: 13 Page(s): 189
    12/18/2023 Authors: Bhutani M; Blue BJ; Cole C; Badros AZ; Usmani SZ; Nooka AK; Bernal-Mizrachi L; Mikhael J
  • Variability in Cytogenetic Testing for Multiple Myeloma: A Comprehensive Analysis From Across the United States.
    JCO Oncol Pract Volume: 16 Page(s): e1169 - e1180
    10/01/2020 Authors: Yu Y; Brown Wade N; Hwang AE; Nooka AK; Fiala MA; Mohrbacher A; Peters ES; Pawlish K; Bock C; Van Den Berg DJ
  • Health Insurance Coverage Disruptions and Cancer Care and Outcomes: Systematic Review of Published Research.
    J Natl Cancer Inst Volume: 112 Page(s): 671 - 687
    07/01/2020 Authors: Yabroff KR; Reeder-Hayes K; Zhao J; Halpern MT; Lopez AM; Bernal-Mizrachi L; Collier AB; Neuner J; Phillips J; Blackstock W
  • A meta-analysis of genome-wide association study and eQTL analysis of multiple myeloma among African Americans
    Volume: 29
    06/01/2020 Authors: Du Z; Weinhold N; Song GC; Rand KA; Van den Berg DJ; Hwang AE; Sheng X; Hom V; Ailawadhi S; Nooka AK
  • Epstein-Barr virus prevalence in classical Hodgkin lymphoma tumors by race/ethnicity in a multiethnic US population
    Volume: 29
    06/01/2020 Authors: Bolanos R; Hwang A; Aparicio J; Chao C; Qurashi N; Flowers C; Pullarkat S; Conti D; Wang S; Mann K
  • Adherence to Oral Anticancer Medications After Implementation of an Ambulatory Adherence Program at a Large Urban Academic Hospital.
    JCO Oncol Pract Volume: 16 Page(s): e350 - e356
    04/01/2020 Authors: Curry MA; Chineke I; Redelico T; Terrell C; Bell W; Flood D; Mishra P; LaFollette J; Power S; Bernal-Mizrachi L
  • Improving Documentation of Pain and Constipation Management Within the Cancer Center of a Large Urban Academic Hospital.
    JCO Oncol Pract Volume: 16 Page(s): e251 - e256
    03/01/2020 Authors: Chineke I; Adams Curry M; Bell W; Flood D; Mishra P; Power S; Bernal-Mizrachi L
  • A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry.
    Blood Adv Volume: 4 Page(s): 181 - 190
    01/14/2020 Authors: Du Z; Weinhold N; Song GC; Rand KA; Van Den Berg DJ; Hwang AE; Sheng X; Hom V; Ailawadhi S; Nooka AK
  • Gain of Chromosome 1q is associated with early progression in multiple myeloma patients treated with lenalidomide, bortezomib, and dexamethasone.
    Blood Cancer J Volume: 9 Page(s): 94
    11/25/2019 Authors: Schmidt TM; Barwick BG; Joseph N; Heffner LT; Hofmeister CC; Bernal L; Dhodapkar MV; Gupta VA; Jaye DL; Wu J
  • Phase II Trial of Ixazomib and Dexamethasone Versus Ixazomib, Dexamethasone and Lenalidomide, Randomized with NFKB2 Rearrangement. (Proteasome Inhibitor NFKB2 Rearrangement Driven Trial, PINR)
    Volume: 134
    11/13/2019 Authors: Bernal-Mizrachi L; Nooka AK; Heffner L; Cole CE; Ye JC; Vij R; Hofmeister CC; Rushton J; Chen Z; Chang Z
  • Trasposon Mediated Horizontal Gene Transfer (T-HGT) of Circulating Tumor DNA Reshapes MM Clonal Architecture
    Volume: 134
    11/13/2019 Authors: Cinar M; Flygare S; Mosunjac M; Nagaraju G; Park D; Faith S; Saxe D; Bernal-Mizrachi L
  • Comprehensive Investigation of White Blood Cell and Gene Expression Profiles As Risk Factors for Multiple Myeloma in African Americans
    Volume: 134
    11/13/2019 Authors: Kachuri L; Du Z; Weinhold N; Song G; Rand KA; Van den Berg D; Hwang A; Sheng X; Hom V; Ailawadhi S
  • Phase II Trial of Ixazomib and Dexamethasone Versus Ixazomib, Dexamethasone and Lenalidomide, Randomized with NFKB2 Rearrangement. (Proteasome Inhibitor NFKB2 Rearrangement Driven Trial, PINR)
    Volume: 19 Page(s): E243 - E244
    10/01/2019 Authors: Bernal L; Nooka A; Cole C; Heffner LT; Ye JC; Vij R; Chen Z; Zhang C; Rushton J; Munevver C
  • Improving documentation of pain and constipation management within the cancer center of a large urban academic hospital.
    Volume: 37
    09/20/2019 Authors: Chineke IG; Curry MA; Dutcher G; Power S; Bernal-Mizrachi L
  • Epstein-Barr virus prevalence in classical Hodgkin lymphoma tumors is explained by histologic subtype, not race/ethnicity in a multiethnic US population
    Volume: 79
    07/01/2019 Authors: Bolanos R; Hwang A; Chao C; Flowers C; Pullarkat S; Aparicio J; Wang S; Mann K; Bernal-Mizrachi L; Song J
  • Epstein-Barr Virus prevalence in classic Hodgkin lymphoma is predicted by histologic subtype and not race or ethnicity a multiethnic US cohort
    Volume: 99
    03/01/2019 Authors: Bolanos R; Hwang A; Chao C; Flowers C; Pullarkat S; Aparicio J; Wang S; Mann K; Bernal-Mizrachi L; Song J
  • Epstein-Barr Virus prevalence in classic Hodgkin lymphoma is predicted by histologic subtype and not race or ethnicity a multiethnic US cohort
    Volume: 32
    03/01/2019 Authors: Bolanos R; Hwang A; Chao C; Flowers C; Pullarkat S; Aparicio J; Wang S; Mann K; Bernal-Mizrachi L; Song J
  • Genetic Analysis of Plasmablastic Lymphomas in HIV (+) Patients Reveals Novel Driver Regulators of the Noncanonical NF-kappa B Pathway
    Volume: 132
    11/29/2018 Authors: Cinar M; Rong H-R; Chineke I; Louissaint A; Chapman-Fredricks JR; Vega F; Gunthel CJ; Love C; Mosunjac M; Flowers CR
  • Smoothened stabilizes and protects TRAF6 from degradation: A novel non-canonical role of smoothened with implications in lymphoma biology.
    Cancer Lett Volume: 436 Page(s): 149 - 158
    11/01/2018 Authors: Qu C; Kunkalla K; Vaghefi A; Frederiksen JK; Liu Y; Chapman JR; Blonska M; Bernal-Mizrachi L; Alderuccio JP; Lossos IS
  • Small target detection using Pinpoint FISH
    Volume: 224 Page(s): 68 - 68
    08/01/2018 Authors: Robinson E; Hughes S; Rushton J; Bernal-Mizrachi L; Kaya-Okur H
  • A meta-analysis of genome-wide association studies of multiple myeloma among African Americans
    Volume: 78
    07/01/2018 Authors: Du Z; Song C; Rand K; Weinhold N; Van den Berg D; Hwang A; Sheng X; Hom V; Ailawadhi S; Nooka AK
  • Assessment of Provider Adherence to Recommended Monitoring Parameters for Oral Anticancer Medications.
    J Oncol Pract Volume: 14 Page(s): e446 - e450
    07/01/2018 Authors: Redelico TJ; Walton SM; LaFollette J; Adams Curry M; Bernal-Mizrachi L
  • Adherence to oral anticancer medications after implementation of an ambulatory adherence program at a large urban academic hospital.
    Volume: 36
    05/20/2018 Authors: Curry MA; Redelico T; Terrell C; Chineke IG; LaFollette JA; Bell W; Flood D; Mishra P; Power S; Bernal-Mizrachi L
  • Improving documentation of pain and constipation management within the cancer center of a large public healthcare network.
    Volume: 36
    05/20/2018 Authors: Dutcher G; Flood D; Curry MA; Washington A; Mishra P; Streetman C; LaFollette JA; Bell W; Smith S; Senchery MC
  • 14-3-3 binds the proteasome, limits proteolytic function and enhances sensitivity to proteasome inhibitors.
    Leukemia Volume: 32 Page(s): 744 - 751
    03/01/2018 Authors: Gu Y; Xu K; Torre C; Samur M; Barwick BG; Rupji M; Arora J; Neri P; Kaufman J; Nooka A
  • A Meta-Analysis of Genome-Wide Association Studies of Multiple Myeloma in Persons of African Ancestry [African-American Multiple Myeloma Study (AAMMS)] Identifies Suggestive Risk Variants
    Volume: 130
    12/07/2017 Authors: Du Z; Weinhold N; Van den Berg D; Hwang A; Sheng X; Hom V; Ailawadhi S; Nooka AK; Singhal S; Pawlish K
  • Genetic and Functional Drivers of Diffuse Large BCell Lymphoma.
    Cell Volume: 171 Page(s): 481 - 494.e15
    10/05/2017 Authors: Reddy A; Zhang J; Davis NS; Moffitt AB; Love CL; Waldrop A; Leppa S; Pasanen A; Meriranta L; Karjalainen-Lindsberg M-L
  • Molecular impact of selective NFKB1 and NFKB2 signaling on DLBCL phenotype.
    Oncogene Volume: 36 Page(s): 4224 - 4232
    07/20/2017 Authors: Guo X; Koff JL; Moffitt AB; Cinar M; Ramachandiran S; Chen Z; Switchenko JM; Mosunjac M; Neill SG; Mann KP
  • Factors influencing Quality of FDG PET/CT scan in Multiple Myeloma
    Volume: 58
    05/01/2017 Authors: Bhat S; Arora M; Long E; Bernal-Mizrachi L; Halkar R
  • The Genetic Basis of Hepatosplenic T-cell Lymphoma.
    Cancer Discov Volume: 7 Page(s): 369 - 379
    04/01/2017 Authors: McKinney M; Moffitt AB; Gaulard P; Travert M; De Leval L; Nicolae A; Raffeld M; Jaffe ES; Pittaluga S; Xi L
  • HLA Haplotypes Are Associated with Multiple Myeloma Risk in the African American Multiple Myeloma Study (AAMMS)
    Volume: 128
    12/02/2016 Authors: Gragert L; Hwang A; Bernal-Mizrachi L; Ailawadhi S; Singhal S; Vandenberg DJ; Sheng X; Stram A; Conti DV; Rand KA
  • A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci.
    Cancer Epidemiol Biomarkers Prev Volume: 25 Page(s): 1609 - 1618
    12/01/2016 Authors: Rand KA; Song C; Dean E; Serie DJ; Curtin K; Sheng X; Hu D; Huff CA; Bernal-Mizrachi L; Tomasson MH
  • Relations Between Residential Proximity to EPA-Designated Toxic Release Sites and Diffuse Large B-Cell Lymphoma Incidence.
    South Med J Volume: 109 Page(s): 606 - 614
    10/01/2016 Authors: Bulka C; Nastoupil LJ; Koff JL; Bernal-Mizrachi L; Ward KC; Williams JN; Bayakly AR; Switchenko JM; Waller LA; Flowers CR
  • DECREASING EARLY DEATHS IN ACUTE PROMYELOCYTIC LEUKEMIA (APL) IN AN ACADEMIC CENTER IN THE US BY USING A SIMPLIFIED TREATMENT ALGORITHM AND DEDICATED APL EXPERTS
    Volume: 101 Page(s): 675 - 676
    06/01/2016 Authors: Jillella A; Mody M; Harpaul G; Arellano M; Khoury H; Al-Kadhimi Z; McLemore M; Winton E; Gaddh M; Heffner L
  • Gene integrated set profile analysis: a context-based approach for inferring biological endpoints.
    Nucleic Acids Res Volume: 44 Page(s): e69
    04/20/2016 Authors: Kowalski J; Dwivedi B; Newman S; Switchenko JM; Pauly R; Gutman DA; Arora J; Gandhi K; Ainslie K; Doho G
  • Referral Patterns and Clinical Outcomes for Transplant-Eligible Lymphoma and Myeloma Patients Evaluated at an Urban County Hospital.
    J Stem Cell Res Ther Volume: 6
    01/01/2016 Authors: Yun HD; Dossul T; Bernal-Mizrachi L; Switchenko J; Ndibe C; Ibraheem A; Dixon MD; Langston AA; Nooka AK; Flowers CR
  • The potential relevance of the endocannabinoid, 2-arachidonoylglycerol, in diffuse large B-cell lymphoma.
    Oncoscience Volume: 3 Page(s): 31 - 41
    01/01/2016 Authors: Zhang J; Medina-Cleghorn D; Bernal-Mizrachi L; Bracci PM; Hubbard A; Conde L; Riby J; Nomura DK; Skibola CF
  • Suvmax in 18-Fluorodeoxyglucose PET/CT Potentially Predict the Estimation of a Positive Biopsy in Cases of Lymphoma
    Volume: 126
    12/03/2015 Authors: Chandra P; Akinbobuyi O; Liao A; Arora J; Chen Z; Lechowicz MJ; Langston AA; Kowalsky J; Cohen JB; Flowers CR
  • Gene expression analysis of plasmablastic lymphoma identifies downregulation of B-cell receptor signaling and additional unique transcriptional programs.
    Leukemia Volume: 29 Page(s): 2270 - 2273
    11/01/2015 Authors: Chapman J; Gentles AJ; Sujoy V; Vega F; Dumur CI; Blevins TL; Bernal-Mizrachi L; Mosunjac M; Pimentel A; Zhu D
  • Multiple myeloma susceptibility loci examined in African and European ancestry populations
    Volume: 75
    08/01/2015 Authors: Rand KA; Song C; Dean E; Serie D; Curtin K; Hazelett D; Hwang AE; Sheng X; Stram A; Van Den Berg DJ
  • Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-B pathway.
    Int J Cancer Volume: 136 Page(s): 2341 - 2351
    05/15/2015 Authors: Ramachandiran S; Adon A; Guo X; Wang Y; Wang H; Chen Z; Kowalski J; Sunay UR; Young AN; Brown T
  • THINK OUTSIDE THE BOX: A 31 YEAR OLD MALE WITH FEVERS AND MYALGIAS
    Volume: 30 Page(s): S469 - S469
    04/01/2015 Authors: Nasri H; Love E; Bernal-Mizrachi L
  • Intensive chemotherapy and consolidation with high dose therapy and autologous stem cell transplant in patients with mantle cell lymphoma.
    Leuk Lymphoma Volume: 56 Page(s): 383 - 389
    02/01/2015 Authors: Nastoupil LJ; Shenoy PJ; Ambinder A; Koff JL; Nooka AK; Waller EK; Langston A; Seward M; Kaufman JL; Bernal-Mizrachi L
  • A time to kill: targeting apoptosis in cancer.
    Int J Mol Sci Volume: 16 Page(s): 2942 - 2955
    01/28/2015 Authors: Koff JL; Ramachandiran S; Bernal-Mizrachi L
  • Genetic Susceptibility Markers of Multiple Myeloma in African-Americans
    BLOOD Volume: 124
    12/06/2014 Authors: Rand KA; Song C; Hwang AE; Huff CA; Bernal-Mizrachi L; Tomasson MH; Ailawadhi S; Van Den Berg DJ; Sheng X; Graff JJ
  • Racial Disparity in Patients with Multiple Myeloma Are Blunted in the Era Novel Therapies
    BLOOD Volume: 124
    12/06/2014 Authors: Bernal-Mizrachi L; Nooka AK; Pooja C; Chatwal MS; Kim S; Chen Z; Kowalski J; Kaufman JL; Lonial S
  • Non-Inferior Clinical Outcomes for Lymphoma and Myeloma Patients Referred from a County Hospital to an Academic Transplant Center for Autologous Stem Cell Transplantation
    Volume: 124
    12/06/2014 Authors: Yun HD; Dossul T; Bernal-Mizrachi L; Switchenko J; Ndibe C; Ibraheem A; Langston A; Pentz R; Waller EK
  • Strand-Specific Total RNA Sequencing Establishes the Complete Transcriptome and Alternative Splicing Repertoire in Diffuse Large B Cell Lymphoma
    Volume: 124
    12/06/2014 Authors: Greenough A; Moffitt A; Jima D; Healy J; Patel A; Richards KL; Fedoriw YD; Dunphy C; Choi WWL; Srivastava G
  • Outcomes for Myeloma in the Era of Lenalidomide Maintenance Are Not Different Among Ethnic Groups Following Autologous Transplant
    Volume: 124
    12/06/2014 Authors: Pooja C; Nooka AK; Chatwal MS; Kim S; Chen Z; Kowalski J; Kaufman JL; Lonial S; Bernal-Mizrachi L
  • Detection of NFKB2 3'end Loos By Quantitative PCR (QPCR) or Detection of NFKB2 Rearrangements Correlate with Bortezomib Response in Multiple Myeloma
    Volume: 124
    12/06/2014 Authors: Ramachandiran S; Koff JL; Garderet L; Saxe D; Ikhlef S; Kelkar N; Kaplan L; El-Cheikh J; Switchenko JM; Sunay S
  • Obesity is associated with clinical characteristics in African American multiple myeloma patients
    Volume: 74
    10/01/2014 Authors: Hwang AE; Ailwadhi S; Huff CA; Bernal-Mizrachi L; Haiman CA; Peters E; Singhal S; Pawlish K; Bock C; Zimmerman T
  • Puffing the 'Activate' in Activated B Cell-like Diffuse Large B Cell Lymphoma: A Role for the Noncanonical NF-kappa B Pathway
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA Volume: 14 Page(s): S143 - S143
    09/01/2014 Authors: Koff JL; Guo X; Ramachandiran S; Switchenko JM; Mosunjac MB; Neill SG; Mann K; Bagirov M; Flowers CR; Lossos IS
  • Over one-third of African-American MGUS and multiple myeloma patients are carriers of hyperphosphorylated paratarg-7, an autosomal dominantly inherited risk factor for MGUS/MM.
    Int J Cancer Volume: 135 Page(s): 934 - 938
    08/15/2014 Authors: Zwick C; Held G; Auth M; Bernal-Mizrachi L; Roback JD; Sunay S; Iida S; Kuroda Y; Sakai A; Ziepert M
  • Sensitivity and specificity of cerebrospinal fluid flow cytometry for the diagnosis of leukemic meningitis in acute lymphoblastic leukemia/lymphoma.
    Leuk Lymphoma Volume: 55 Page(s): 1498 - 1500
    07/01/2014 Authors: Mitri Z; Siddiqui MT; El Rassi F; Holden JT; Heffner LT; Langston A; Waller EK; Winton E; McLemore M; Bernal-Mizrachi L
  • MLN4924, an NAE inhibitor, suppresses AKT and mTOR signaling via upregulation of REDD1 in human myeloma cells.
    Blood Volume: 123 Page(s): 3269 - 3276
    05/22/2014 Authors: Gu Y; Kaufman JL; Bernal L; Torre C; Matulis SM; Harvey RD; Chen J; Sun S-Y; Boise LH; Lonial S
  • Using RNA-Seq, SNP-CN and Targeted Deep Sequencing To Improve The Diagnostic Paradigm In Multiple Myeloma
    Volume: 122
    11/15/2013 Authors: Rossi MR; Newman S; Nooka AK; Kaufman JL; Bahlis NJ; Neri P; Matulis SM; Bernal-Mizrachi L; Gupta VA; Varma A
  • Whole Genome and Exome Sequencing Defines The Genetic Landscape Of Hepatosplenic T-Cell Lymphoma
    Volume: 122
    11/15/2013 Authors: Scotland P; Gaulard P; Love CL; Fataccioli V; Travert M; De Leval L; Weisenburger DD; Czader M; Parihar M; Nair R
  • Relationship Between Residential Proximity To Environmental Protection Agency (EPA) Designated Toxic Release Sites and The Risk Of Diffuse Large B-Cell Lymphoma (DLBCL)
    Volume: 122
    11/15/2013 Authors: Bulka C; Nastoupil LJ; Koff J; Bernal L; Ward K; Bayakly R; Switchenko J; Waller L; Flowers CR
  • Obesity In Young Adulthood Is Associated With Early Onset Multiple Myeloma In African Americans
    Volume: 122
    11/15/2013 Authors: Hwang AE; Ailawadhi S; Bernal-Mizrachi L; Zimmerman TM; Haiman C; Van den Berg DJ; Pawlish K; Mohrbacher AM; Terebelo H; Birmann BM
  • Epsilon aminocaproic acid prevents bleeding in severely thrombocytopenic patients with hematological malignancies.
    Cancer Volume: 119 Page(s): 3784 - 3787
    11/01/2013 Authors: Antun AG; Gleason S; Arellano M; Langston AA; McLemore ML; Gaddh M; el Rassi F; Bernal-Mizrachi L; Galipeau J; Heffner LT
  • Examining racial differences in diffuse large B-cell lymphoma presentation and survival.
    Leuk Lymphoma Volume: 54 Page(s): 268 - 276
    02/01/2013 Authors: Flowers CR; Shenoy PJ; Borate U; Bumpers K; Douglas-Holland T; King N; Brawley OW; Lipscomb J; Lechowicz MJ; Sinha R
  • Genetic heterogeneity of diffuse large B-cell lymphoma.
    Proc Natl Acad Sci U S A Volume: 110 Page(s): 1398 - 1403
    01/22/2013 Authors: Zhang J; Grubor V; Love CL; Banerjee A; Richards KL; Mieczkowski PA; Dunphy C; Choi W; Au WY; Srivastava G
  • The genetic landscape of mutations in Burkitt lymphoma.
    Nat Genet Volume: 44 Page(s): 1321 - 1325
    12/01/2012 Authors: Love C; Sun Z; Jima D; Li G; Zhang J; Miles R; Richards KL; Dunphy CH; Choi WWL; Srivastava G
  • Vitamin D suppression of endoplasmic reticulum stress promotes an antiatherogenic monocyte/macrophage phenotype in type 2 diabetic patients.
    J Biol Chem Volume: 287 Page(s): 38482 - 38494
    11/09/2012 Authors: Riek AE; Oh J; Sprague JE; Timpson A; de las Fuentes L; Bernal-Mizrachi L; Schechtman KB; Bernal-Mizrachi C
  • One third of Afroamerican patients with MGUS/MM are carriers of hyperphosphorylated paratarg-7, the first autosomal-dominantly inherited risk factor for hematological neoplasms, to develop monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM)
    ONKOLOGIE Volume: 35 Page(s): 141 - 141
    10/01/2012 Authors: Preuss K-D; Bernal-Mizrachi L; Fadle N; Inagaki A; Shimizu K; Ziepert M; Iida S; Ueda R; Pfreundschuh M
  • Characteristics and outcomes of diffuse large B-cell lymphoma presenting in leukaemic phase.
    Br J Haematol Volume: 158 Page(s): 608 - 614
    09/01/2012 Authors: Muringampurath-John D; Jaye DL; Flowers CR; Saxe D; Chen Z; Lechowicz MJ; Weisenburger DD; Bast M; Arellano ML; Bernal-Mizrachi L
  • The Smac mimetic RMT5265.2HCL induces apoptosis in EBV and HTLV-I associated lymphoma cells by inhibiting XIAP and promoting the mitochondrial release of cytochrome C and Smac.
    Leuk Res Volume: 36 Page(s): 784 - 790
    06/01/2012 Authors: Ramachandiran S; Cain J; Liao A; He Y; Guo X; Boise LH; Fu H; Ratner L; Khoury HJ; Bernal-Mizrachi L
  • Rituximab-hyperfractionated cyclophosphamide, vincristine, adriamycin and dexamethasone alternating with high-dose cytarabine and methotrexate for aggressive non-Hodgkin lymphoma.
    Leuk Lymphoma Volume: 53 Page(s): 725 - 727
    04/01/2012 Authors: Muringampurath-John D; Flowers CR; Toscano M; Zhengjia C; Kaufman JL; Arellano M; Bernal-Mizrachi L; Heffner LT; Lechowicz M-J; McLemore M
  • New Challenges in the Management of Diffuse Large B-Cell Lymphoma.
    Treat Strategies Hematol Volume: 2 Page(s): 68 - 73
    01/01/2012 Authors: Flowers CR; Nastoupil LJ; Bernal-Mizrachi L; Rose AC; Sinha R
  • Truncation of NF-KB2 Is Associated with Poor Response to Bortezomib Treatment in Multiple Myeloma
    Volume: 118 Page(s): 1248 - 1248
    11/18/2011 Authors: Ramachandiran S; Guo X; Garderet L; Ikhlef S; El-cheikh J; Weil MR; Young AN; Bagirov M; Lonial S; Chen Z
  • New Insights in the Pathogenesis of MGUS, Multiple Myeloma (MM) and Waldenstrom's Macroglobulinemia (WM): Chronic Antigenic Stimulation by Autoantigenic Targets of Paraproteins Is Mediated by CD4(+) t-Cells
    Volume: 118 Page(s): 218 - 219
    11/18/2011 Authors: Grass S; Preuss K-D; Wikowicz A; Fadle N; Regitz E; Held G; Bernal-Mizrachi L; Raudies S; Thiele H; Pfreundschuh M
  • Whole Genome and Exome Sequencing Reveals the Genetic Landscape of Burkitt Lymphoma
    Volume: 118 Page(s): 199 - 200
    11/18/2011 Authors: Love CL; Jima D; Zhang J; Grubor V; Miles RR; Dunphy CH; Richards KL; Choi WWL; Au WY; Srivastava G
  • Prognostic significance of leukopenia at the time of diagnosis in acute myeloid leukemia.
    Clin Lymphoma Myeloma Leuk Volume: 11 Page(s): 427 - 432
    10/01/2011 Authors: Arellano M; Bernal-Mizrachi L; Pan L; Tighiouart M; Souza L; Guo X; McLemore M; Lima L; Sunay S; Heffner LT
  • Does pretreatment fluorescence in situ hybridization for BCR-ABL predict imatinib-associated hematologic toxicity in chronic myeloid leukemia?
    Leuk Lymphoma Volume: 52 Page(s): 1010 - 1016
    06/01/2011 Authors: Lima LM; Sampat K; Assouline S; Saxe D; Nault S; Tighiouart M; McLemore M; Arellano M; Winton E; Bernal-Mizrachi L
  • Peripheral blood monitoring of chronic myeloid leukemia during treatment with imatinib, second-line agents, and beyond.
    Cancer Volume: 117 Page(s): 1245 - 1252
    03/15/2011 Authors: Lima L; Bernal-Mizrachi L; Saxe D; Mann KP; Tighiouart M; Arellano M; Heffner L; McLemore M; Langston A; Winton E
  • Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs.
    Blood Volume: 116 Page(s): e118 - e127
    12/02/2010 Authors: Jima DD; Zhang J; Jacobs C; Richards KL; Dunphy CH; Choi WWL; Au WY; Srivastava G; Czader MB; Rizzieri DA
  • Alternative Splicing Is a Major Mechanism of Gene Regulation In Diffuse Large B Cell Lymphoma
    Volume: 116 Page(s): 351 - 352
    11/19/2010 Authors: Jacobs CL; Patel A; Jima D; Liu Q; Greenough A; Zhang J; Dunphy C; Richards K; Choi W; Srivastava G
  • Prognostic Significance of Circulating Lymphoma Cells in Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)
    Volume: 114 Page(s): 1151 - 1152
    11/20/2009 Authors: Muringampurath-John D; Flowers CR; Jabbar AA; Sinha R; Arellano M; Bernal-Mizrachi L; Kaufman JL; Jaye DL; Chen Z; Lechowicz MJ
  • Genomic Stability: A Novel Function of NF-Kb in Lymphomas
    Volume: 114 Page(s): 1255 - 1256
    11/20/2009 Authors: Ramachandiran S; Adone A; Guo X; Liao A; Sunay UR; Ratner L; Fu H; Lossos IS; Saavedra H; Bernal-Mizrachi L
  • 1,25(OH)2 vitamin d inhibits foam cell formation and suppresses macrophage cholesterol uptake in patients with type 2 diabetes mellitus.
    Circulation Volume: 120 Page(s): 687 - 698
    08/25/2009 Authors: Oh J; Weng S; Felton SK; Bhandare S; Riek A; Butler B; Proctor BM; Petty M; Chen Z; Schechtman KB
  • Does pre-imatinib (IM) fluorescence in situ hybridization (FISH) predict myelosuppression and outcomes in chronic myeloid leukemia (CML)?
    Volume: 27
    05/20/2009 Authors: Lima L; Assouline SE; Saxe D; Mann K; McLemore M; Souza L; Arellano M; Winton EF; Bernal-Mizrachi L; Khoury HJ
  • Does pre-imatinib (IM) fluorescence in situ hybridization (FISH) predict myelosuppression and outcomes in chronic myeloid leukemia (CML)?
    J Clin Oncol Volume: 27 Page(s): 7071
    05/20/2009 Authors: Lima L; Assouline SE; Saxe D; Mann K; McLemore M; Souza L; Arellano M; Winton EF; Bernal-Mizrachi L; Khoury HJ
  • Monitoring chronic myeloid leukemia (CML) response to tyrosine kinase inhibitors (TKI) and homoharringtonine (HHT) using peripheral blood (PB) fluorescence in situ hybridization (FISH) and quantitative RT-PCR (Q-PCR): Are bone marrow biopsies still needed?
    J Clin Oncol Volume: 27 Page(s): 7064
    05/20/2009 Authors: Khoury HJ; Lima L; Saxe D; Mann KP; Arellano M; Heffner L; Bernal-Mizrachi L; McLemore M; Langston A; Winton E
  • Monitoring chronic myeloid leukemia (CML) response to tyrosine kinase inhibitors (TKI) and homoharringtonine (HHT) using peripheral blood (PB) fluorescence in situ hybridization (FISH) and quantitative RT-PCR (Q-PCR): Are bone marrow biopsies still needed?
    Volume: 27
    05/20/2009 Authors: Khoury HJ; Lima L; Saxe D; Mann KP; Arellano M; Heffner L; Bernal-Mizrachi L; McLemore M; Langston A; Winton E
  • Down-regulation of 14-3-3zeta suppresses anchorage-independent growth of lung cancer cells through anoikis activation.
    Proc Natl Acad Sci U S A Volume: 105 Page(s): 162 - 167
    01/08/2008 Authors: Li Z; Zhao J; Du Y; Park HR; Sun S-Y; Bernal-Mizrachi L; Aitken A; Khuri FR; Fu H
  • Bioluminescence imaging of spontaneous lymphomas and contribution of distinct NFKB pathways.
    Volume: 108 Page(s): 673A - 673A
    11/16/2006 Authors: Ratner L; Bernal-Mizrachi L; Rauch D; Harding J; Gross S; Piwnica-Worms D
  • Targeting xIAP is more important than Bcl-xl in lymphomas with constitutive activation of NF-kB.
    Volume: 108 Page(s): 676A - 677A
    11/16/2006 Authors: He Y; Cain J; Ratner L; Bernal-Mizrachi L
  • Novel siRNA expressing lymphoma model identify distinct molecular mechanisms regulating NFkB1 and NFkB2 induced cell proliferation.
    Volume: 108 Page(s): 672A - 672A
    11/16/2006 Authors: Bernal-Mizrachi L; Harding J; Lee R
  • The role of NF-{kappa}B-1 and NF-{kappa}B-2-mediated resistance to apoptosis in lymphomas.
    Proc Natl Acad Sci U S A Volume: 103 Page(s): 9220 - 9225
    06/13/2006 Authors: Bernal-Mizrachi L; Lovly CM; Ratner L
  • Accumulation of NFkB1 (p105) and NFkB2 (p100) is essential for apoptosis induced by proteasome inhibition in a lymphoma model.
    Volume: 106 Page(s): 733A - 733A
    11/16/2005 Authors: Bernal-Mizrachi L; Edwards SK; Ratner L
  • Role of the NF-B pathways in Tax-induced resistance to apoptosis
    Volume: 21 Page(s): 505 - 505
    05/01/2005 Authors: Bernal-Mizrachi L; Ratner L
  • Endothelial microparticles correlate with high-risk angiographic lesions in acute coronary syndromes.
    Int J Cardiol Volume: 97 Page(s): 439 - 446
    12/01/2004 Authors: Bernal-Mizrachi L; Jy W; Fierro C; Macdonough R; Velazques HA; Purow J; Jimenez JJ; Horstman LL; Ferreira A; de Marchena E
  • Levels of GP-IIb/IIIa positive platelet microparticles (PMP) but not CD31+/CD42+PMP predict adverse outcomes in troponin-negative patients with chest pain.
    Volume: 104 Page(s): 707A - 708A
    11/16/2004 Authors: Chirinos JA; Velazquez H; Canoniero M; Soriano AO; Bernal-Mizrachi L; Jy W; Horstman LL; Jimenez JJ; De Marchena E; Ferreira A
  • High levels of circulating endothelial microparticles in patients with acute coronary syndromes.
    Am Heart J Volume: 145 Page(s): 962 - 970
    06/01/2003 Authors: Bernal-Mizrachi L; Jy W; Jimenez JJ; Pastor J; Mauro LM; Horstman LL; de Marchena E; Ahn YS
  • Repeated ischemia reduces the capacity of endothelium to release endothelial microparticles (EMP): In vivo experiment and clinical observations.
    Volume: 100 Page(s): 71B - 71B
    11/16/2002 Authors: Bernal-Mizrachi L; Valle AO; Soriano AO; Jimenez JJ; Horstman LL; Ahn YS
  • Normal levels of endothelial microparticles (EMP) predict negative cardiac stress test in patients with chest pain.
    Volume: 100 Page(s): 76B - 76B
    11/16/2002 Authors: Bernal-Mizrachi L; Velasquez HS; Valle M; Soriano AO; Zambrano JP; Mcdonough R; Jy WC; Ahn YS; Mallon SM
  • Distinct species of endothelial microparticies (EMP) reflect distinct kinds of endothelial injury: EMP as a promising new marker of vascular disorders.
    Volume: 100 Page(s): 73B - 73B
    11/16/2002 Authors: Jimenez JJ; Jy WC; Mauro LM; Horstman LL; Bernal-Mizrachi L; Preston RA; Minagar A; Gonzalez-Quintero VH; Ahn YS
  • Endothelial microparticles correlate with high-risk angiographic lesions in acute coronary syndromes
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Volume: 39 Page(s): 273A - 273A
    03/06/2002 Authors: Bernal-Mizrachi L; Fierro C; McDonough E; Purow J; Jy W; Velasquez HS; Jimenez JJ; Horstman LL; Ahn YS; Marchena E
  • Long-term remission in myeloproliferative disorder (MPD) by combination therapy with danazol and busulfan.
    BLOOD Volume: 98 Page(s): 277B - 277B
    11/16/2001 Authors: Ahn YS; Bernal-Mizrachi L; Jimenez JJ; Horstman LL; Saltzman MA; Dacas SB; Jy W
  • The role of interleukin-6 in cases of cardiac myxoma. Clinical features, immunologic abnormalities, and a possible role in recurrence.
    Tex Heart Inst J Volume: 28 Page(s): 3 - 7
    01/01/2001 Authors: Mendoza CE; Rosado MF; Bernal L
  • TTP plasma induces release of procoagulant EMP (endothelial microparticles) from endothelial cells in culture; And EMP is markedly elevated in TTP patients.
    BLOOD Volume: 96 Page(s): 531A - 531A
    11/16/2000 Authors: Jimenez JJ; Jy W; Horstman LL; Mauro LM; Bernal-Mizrachi L; Ahn YS
  • 13th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI) Bethesda, MD, USA. 7-8 November 2011. Abstracts.

    Authors: Zhang J; Grubor V; Love CL; Banerjee A; Richards KL; Miezcowski P; Dunphy CH; Choi WWL; Auv W-Y; Srivastava G
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