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Profile

Kathryn Oliver PhD

  • Department of Pediatrics
    Assistant Professor
  • (404) 727-8763
  • kolive3@emory.edu
  • Website
  • Website
Head shot of Kathryn Oliver

Education

Degrees

  • PhD, Genetics from University of Alabama at Birmingham
  • MS, Microbiology from Auburn University
  • BS, Zoology from Auburn University

Research

Publications

  • Recent developments in cystic fibrosis drug discovery: where are we today?
    Expert Opin Drug Discov Volume: 20 Page(s): 659 - 682
    05/01/2025 Authors: Lopes-Pacheco M; Winters AG; Jackson JJ; Olson Rd JA; Kim M; Ledwitch KV; Tedman A; Jhangiani AR; Schlebach JP; Meiler J
  • Racial inequities and rare CFTR variants: Impact on cystic fibrosis diagnosis and treatment.
    J Clin Transl Endocrinol Volume: 36 Page(s): 100344
    06/01/2024 Authors: Wu M; Davis JD; Zhao C; Daley T; Oliver KE
  • Cystic Fibrosis Foundation Evidence-Based Guideline for the Management of CRMS/CFSPID.
    Pediatrics Volume: 153
    05/01/2024 Authors: Green DM; Lahiri T; Raraigh KS; Ruiz F; Spano J; Antos N; Bonitz L; Christon L; Gregoire-Bottex M; Hale JE
  • Benchmarking AlphaMissense Pathogenicity Predictions Against Cystic Fibrosis Variants.

    01/04/2024 Authors: McDonald EF; Oliver KE; Schlebach JP; Meiler J; Plate L
  • Benchmarking AlphaMissense pathogenicity predictions against cystic fibrosis variants.
    PLoS One Volume: 19 Page(s): e0297560
    01/01/2024 Authors: McDonald EF; Oliver KE; Schlebach JP; Meiler J; Plate L
  • General trends in the effects of VX-661 and VX-445 on the plasma membrane expression of clinical CFTR variants.
    Cell Chem Biol Volume: 30 Page(s): 632 - 642.e5
    06/15/2023 Authors: McKee AG; McDonald EF; Penn WD; Kuntz CP; Noguera K; Chamness LM; Roushar FJ; Meiler J; Oliver KE; Plate L
  • The revolution of personalized pharmacotherapies for cystic fibrosis: what does the future hold?
    Expert Opin Pharmacother Volume: 24 Page(s): 1545 - 1565
    01/01/2023 Authors: Oliver KE; Carlon MS; Pedemonte N; Lopes-Pacheco M
  • Features of CFTR mRNA and implications for therapeutics development.
    Front Genet Volume: 14 Page(s): 1166529
    01/01/2023 Authors: Jackson JJ; Mao Y; White TR; Foye C; Oliver KE
  • Positive epistasis between disease-causing missense mutations and silent polymorphism with effect on mRNA translation velocity.
    Proc Natl Acad Sci U S A Volume: 118
    01/26/2021 Authors: Rauscher R; Bampi GB; Guevara-Ferrer M; Santos LA; Joshi D; Mark D; Strug LJ; Rommens JM; Ballmann M; Sorscher EJ
  • The CFTR P67L variant reveals a key role for N-terminal lasso helices in channel folding, maturation, and pharmacologic rescue.
    J Biol Chem Volume: 296 Page(s): 100598
    01/01/2021 Authors: Sabusap CM; Joshi D; Simhaev L; Oliver KE; Senderowitz H; van Willigen M; Braakman I; Rab A; Sorscher EJ; Hong JS
  • Global assessment of the integrated stress response in CF patient-derived airway and intestinal tissues.
    J Cyst Fibros Volume: 19 Page(s): 1021 - 1026
    11/01/2020 Authors: Bampi GB; Rauscher R; Kirchner S; Oliver KE; Bijvelds MJC; Santos LA; Wagner J; Frizzell RA; de Jonge HR; Sorscher EJ
  • The 34th Annual North American Cystic Fibrosis Conference, October 7-23, 2020.
    Pediatr Pulmonol Volume: 55 Suppl 2 Page(s): S38 - S361
    10/01/2020
  • UTILIZING YEAST PHENOMICS TO DISCOVER GENE INTERACTION NETWORKS THAT INFLUENCE BIOGENESIS OF CFTR NONSENSE ALLELES
    Volume: 55 Page(s): S118 - S119
    10/01/2020 Authors: Oliver KE; Mao Y; Laflin S; Linscott K; Gaines E; Ali H; Hong JS; Rab A; Sorscher EJ; Hartman JL
  • POSITIVE EPISTATIC INTERACTIONS BETWEEN CF-CAUSING VARIANTS AND A SILENT POLYMORPHISM ARE ELICTED THROUGH EFFECTS ON RIBOSOME VELOCITY
    Volume: 55 Page(s): S71 - S71
    10/01/2020 Authors: Rauscher R; Bampi GB; Ferrer MG; Joshi D; Mark D; Strug LJ; Rommens J; Ballman M; Sorscher EJ; Oliver KE
  • Slowing ribosome velocity restores folding and function of mutant CFTR.
    J Clin Invest Volume: 129 Page(s): 5236 - 5253
    12/02/2019 Authors: Oliver KE; Rauscher R; Mijnders M; Wang W; Wolpert MJ; Maya J; Sabusap CM; Kesterson RA; Kirk KL; Rab A
  • Poster Session.
    Volume: 54 Suppl 2 Page(s): S155 - S480
    10/01/2019
  • EPISTATIC EFFECTS OF COMPLEX ALLELES ON CYSTIC FIBROSIS PHENOTYPE - A PROTEIN TRANSLATIONAL PERSPECTIVE
    Volume: 54 Page(s): S198 - S199
    10/01/2019 Authors: Bampi GB; Rauscher R; Oliver KE; Ferrer MG; Joshi D; Mark D; Sutharsan S; Ballman M; Sorscher EJ; Ignatova Z
  • PARTIAL RESCUE OF G542X-AND W1282X-CFTR IS ACHIEVED FOLLOWING SUPPRESSION OF SPECIFIC RIBOSOMAL COMPONENTS
    Volume: 54 Page(s): S199 - S200
    10/01/2019 Authors: Oliver KE; Ali H; Rauscher R; Bampi GB; Santos S; Rab A; Hong JS; Ignatova Z; Sorscher EJ; Hartman JL
  • Assessing cell-specific effects of genetic variations using tRNA microarrays.
    BMC Genomics Volume: 20 Page(s): 549
    07/16/2019 Authors: Polte C; Wedemeyer D; Oliver KE; Wagner J; Bijvelds MJC; Mahoney J; de Jonge HR; Sorscher EJ; Ignatova Z
  • INTEGRATION OF YEAST GENE INTERACTION NETWORK MODELS TO PREDICT MODIFIERS OF CFTR MOLECULAR PHENOTYPE
    Volume: 53 Page(s): 207 - 208
    09/01/2018 Authors: Santos S; Oliver KE; Sorscher EJ; Hartman JL
  • RIBOSOMAL PROTEIN L12 IS A MOLECULAR TARGET SUITABLE FOR RESCUE OF CFTR DEFECTS WITH MULTIPLE DISEASE SUBCATEGORIES
    Volume: 53 Page(s): 148 - 148
    09/01/2018 Authors: Oliver KE; Rauscher R; Ali H; Icyuz M; Rab A; Hong JS; Hartman JL; Ignatova Z; Sorscher EJ
  • EXAMPLES OF CFTR "SUPER-RESPONDERS," AS WELL AS VARIANTS WITH NEGLIGIBLE ACTIVITY AND MINIMAL PHARMACOLOGIC CORRECTION
    Volume: 53 Page(s): 168 - 168
    09/01/2018 Authors: Rab A; Joshi D; Oliver KE; Sorseher EJ; Hong JS
  • Poster Session Abstracts.
    Pediatr Pulmonol Volume: 53 Page(s): S148 - S456
    09/01/2018
  • SUPPRESSION OF PEROXISOME AND RIBOSOMAL CONSTITUENTS PARTIALLY RESTORES PLASMA MEMBRANE LOCALIZATION AND FUNCTION OF W1282X-CFTR
    Volume: 53 Page(s): 209 - 210
    09/01/2018 Authors: Ali H; Icyuz M; Kelly S; Rab A; Hong JS; Bedwell D; Hartman JL; Sorscher EJ; Oliver KE
  • High-Throughput Yeast Phenomics Identifies Genetic Modifiers that Partially Rescue Human W1282X-CFTR
    Volume: 197
    01/01/2018 Authors: Ali H; Oliver KE; Icyuz M; Kelly S; Rab A; Hong JS; Bedwell DM; Hartman JL; Sorscher EJ
  • YEAST PHENOMIC MODELS OF CF-RELEVANT NONSENSE MUTATIONS REVEAL GENE MODIFIER NETWORKS PROMOTING PREMATURE TERMINATION CODON SUPPRESSION
    Volume: 52 Page(s): S270 - S270
    09/01/2017 Authors: Icyuz M; Kelly S; Oliver KE; Mutyam V; Rowe SM; Sorscher EJ; Bedwell DM; Hartman JL
  • THE P67L CFTR BIOGENESIS DEFECT AND ROLE OF N-TERMINAL LASSO HELICES THAT IMPACT CFTR FOLDING AND MATURATION
    Volume: 52 Page(s): S232 - S232
    09/01/2017 Authors: Sabusap CP; Rab A; Oliver KE; Hong J; Sorscher EJ
  • SLOWING TRANSLATION STABILIZES CFTR TRANSMEMBRANE DOMAINS, INCREASES OPEN CHANNEL PROBABILITY AND ENHANCES FOLDING IN VIVO
    Volume: 52 Page(s): S220 - S220
    09/01/2017 Authors: Oliver KE; Rauscher R; Mijnders M; Wang W; Maya J; Kirk KL; Kesterson RA; Hong JS; Braakman I; Hartman JL
  • Transformative therapies for rare CFTR missense alleles.
    Curr Opin Pharmacol Volume: 34 Page(s): 76 - 82
    06/01/2017 Authors: Oliver KE; Han ST; Sorscher EJ; Cutting GR
  • Poster Session Abstracts.
    Pediatr Pulmonol Volume: 51 Page(s): S194 - S485
    10/01/2016
  • RIBOSOMAL TARGETING CORRECTS CFTR CLASS I AND II DEFECTS
    PEDIATRIC PULMONOLOGY Volume: 51 Page(s): 209 - 209
    10/01/2016 Authors: Oliver KE; Wang W; Wolpert MJ; Maya J; Icyuz M; Hong JS; Hartman JL; Sorscher EJ
  • Ribosomal Stalk Protein Silencing Partially Corrects the F508-CFTR Functional Expression Defect.
    PLoS Biol Volume: 14 Page(s): e1002462
    05/01/2016 Authors: Veit G; Oliver K; Apaja PM; Perdomo D; Bidaud-Meynard A; Lin S-T; Guo J; Icyuz M; Sorscher EJ; Hartman JL
  • The 29(th) Annual North American Cystic Fibrosis Conference.
    Pediatr Pulmonol Volume: 50 Suppl 41 Page(s): S1 - S76
    10/01/2015
  • TARGETING THE RIBOSOME AS A NOVEL APPROACH TO CORRECTING CFTR CLASS II TRAFFICKING DEFECTS
    PEDIATRIC PULMONOLOGY Volume: 50 Page(s): 197 - 197
    10/01/2015 Authors: Oliver KE; Veit G; Wolpert M; Guo J; Icyuz M; Hong JS; Wen H; Sorscher EJ; Lukacs GL; Schneider DA
  • YEAST PHENOMIC ANALYSIS OF THE RPL12 MECHANISM THAT MODULATES ABCC-Delta F PROTEIN BIOGENESIS
    PEDIATRIC PULMONOLOGY Volume: 50 Page(s): 254 - 254
    10/01/2015 Authors: Icyuz M; Oliver KE; Schneider DA; Sorscher EJ; Hartman JL
  • Abstracts of the The 28th Annual North American Cystic Fibrosis Conference Georgia World Congress Center, October 9-11, 2014, Atlanta, Georgia.
    Pediatr Pulmonol Volume: 49 Suppl 38 Page(s): S1 - 475
    09/01/2014
  • MODULATING THE DYNAMICS OF RIBOSOME FUNCTION RESCUES F508DEL CFTR MATURATIONAL ARREST
    PEDIATRIC PULMONOLOGY Volume: 49 Page(s): 217 - 217
    09/01/2014 Authors: Oliver KE; Veit G; Icyuz M; Guo J; McClure ML; Hong JS; Wen H; Sorscher EJ; Lukacs GL; Hartman JL
  • Abstracts of the 27th Annual North American Cystic Fibrosis Conference. October 17-19, 2013. Salt Lake City, Utah, USA.
    Pediatr Pulmonol Volume: 48 Suppl 36 Page(s): 103 - 472
    10/01/2013
  • Impact of D-amino acid dehydrogenase on virulence factor production by a Pseudomonas aeruginosa.
    Can J Microbiol Volume: 59 Page(s): 598 - 603
    09/01/2013 Authors: Oliver KE; Silo-Suh L
  • Describing genetic variation and panel detection rates for a diverse cystic fibrosis center in Georgia
    Journal of Cystic Fibrosis
    Authors: Sanchez Russo R; Barr E; Linnemann R; Oliver K; truitt B
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