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Profile

Kavita Dhodapkar

  • SOM: Peds: Neuro-Oncology
    Professor
  • kavita.dhodapkar@emory.edu
  • Children's Healthcare of Atlanta Provider Profile
  • Aflac Cancer & Blood Disorders Center
    Pediatrics
    1760 Haygood Drive
Head shot of Kavita Dhodapkar

Academic Appointment

  • Faculty, Biomedical Engineering Program, Georgia Tech
  • Member, Cancer Biology Graduate Program, Winship Cancer Institute
  • Associate Professor of Pediatrics, Emory University

Education

Degrees

  • MD from Seth G.S. Medical College

Research

Publications

  • Uncovering the rewired IAP-JAK regulatory axis as an immune-dependent vulnerability of LKB1-mutant lung cancer.
    Nat Commun Volume: 16 Page(s): 2324
    03/08/2025 Authors: Shu C; Li J; Rui J; Fan D; Niu Q; Bai R; Cicka D; Doyle S; Wahafu A; Zheng X
  • Plasma Cytokine and Chemokine Profiles Predict Efficacy and Toxicity of Anti-CD19 CAR-T Cell Therapy in Large B-Cell Lymphoma.
    Clin Lymphoma Myeloma Leuk
    02/20/2025 Authors: Zeng F; Zhang H; Wang S; Passang T; Li Y; Funk CR; Wyman S; O'Leary CB; Abousaud AI; Liu Y
  • Immune-aging is linked to clinical malignancy, racial ancestry and vaccine responses in myeloma.
    Blood Adv
    02/05/2025 Authors: Potdar SV; Kapadia S; Azeem MI; Radzievski R; Lakhani K; Joseph NS; Kaufman JL; Hofmeister CC; Gupta VA; Lonial S
  • Divergence of variant antibodies following SARS-CoV-2 booster vaccines in myeloma and impact of hybrid immunity.
    NPJ Vaccines Volume: 9 Page(s): 201
    10/27/2024 Authors: Moreno A; Manning K; Azeem MI; Nooka AK; Ellis M; Manalo RJ; Switchenko JM; Wali B; Kaufman JL; Hofmeister CC
  • Minority report on cancer immunotherapy: focus on elderly and other understudied populations.
    J Immunother Cancer Volume: 12
    10/26/2024 Authors: Dhodapkar K; Portielje J
  • Clinical response and pathway-specific correlates following TIGIT-LAG3 blockade in myeloma: the MyCheckpoint randomized clinical trial.
    Nat Cancer Volume: 5 Page(s): 1459 - 1464
    10/01/2024 Authors: Richard S; Lesokhin AM; Paul B; Kaufman JL; Pianko M; Biran N; Vij R; Doxie DB; Azeem MI; Martillo M
  • Engineering Improved CAR T Cell Products with A Multi-Cytokine Particle Platform for Hematologic and Solid Tumors.
    Adv Healthc Mater Volume: 13 Page(s): e2302425
    06/01/2024 Authors: Lin HK; Uricoli B; Freeman R; Hossian AN; He Z; Anderson JYL; Neffling M; Legier JM; Blake DA; Doxie DB
  • Tregs protect against combination checkpoint blockade toxicity induced by Tph and B cell interactions.
    J Clin Invest Volume: 134
    05/02/2024 Authors: Duffy A; Azeem MI; Kanangat S; Yushak M; Lawson D; Dhodapkar MV; Dhodapkar KM
  • Divergence of variant binding/neutralizing antibodies following SARS-CoV-2 booster vaccines in myeloma: Impact of hybrid immunity.
    Res Sq
    09/21/2023 Authors: Moreno A; Manning K; Azeem MI; Nooka AK; Ellis M; Manalo RJ; Switchenko JM; Wali B; Kaufman JL; Hofmeister CC
  • Role of B cells in immune-related adverse events following checkpoint blockade.
    Immunol Rev Volume: 318 Page(s): 89 - 95
    09/01/2023 Authors: Dhodapkar KM; Duffy A; Dhodapkar MV
  • Divergence of variant binding/neutralizing antibodies following SARS-CoV-2 booster vaccines in myeloma: Impact of hybrid immunity.
    bioRxiv
    08/22/2023 Authors: Moreno A; Manning K; Azeem MI; Nooka AK; Ellis M; Manalo RJ; Switchenko JM; Wali B; Kaufman JL; Hofmeister CC
  • Regulation of antigen-specific T cell infiltration and spatial architecture in multiple myeloma and premalignancy.
    J Clin Invest Volume: 133
    08/01/2023 Authors: Robinson MH; Villa NY; Jaye DL; Nooka AK; Duffy A; McCachren SS; Manalo J; Switchenko JM; Barnes S; Potdar S
  • Outcomes of a radiation sparing approach in medulloblastoma by subgroup in young children: an institutional review.
    Childs Nerv Syst Volume: 39 Page(s): 2095 - 2104
    08/01/2023 Authors: Ronsley R; Triscott J; Stanek J; Rassekh SR; Lum A; Cheng S; Goddard K; McConnell D; Strahlendorf C; Singhal A
  • Engineering a Multi-Cytokine Backpack Platform for Manufacturing Functionally Improved CAR T Cell Products
    Volume: 31 Page(s): 401 - 402
    05/01/2023 Authors: Lin HK; Uricoli B; Hossian AKMN; Freeman R; He Z; Anderson JYL; Neffling M; Legier J; Doxie DB; Nair R
  • Outcome of Children and Adolescents With Primary Intracranial Germinoma Treated With Chemotherapy and Reduced Dose-Field Irradiation: A Prospective Brazilian Experience.
    JCO Glob Oncol Volume: 9 Page(s): e2200257
    04/01/2023 Authors: Cappellano AM; Dassi N; Manano B; Epelman S; Almeida DB; Cavalheiro S; Dastoli PA; Seixas MT; Nicacio JM; Costa MD
  • Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation-Sparing Approaches: An International Cohort Study.
    J Clin Oncol Volume: 41 Page(s): 1921 - 1932
    04/01/2023 Authors: Erker C; Mynarek M; Bailey S; Mazewski CM; Baroni L; Massimino M; Hukin J; Aguilera D; Cappellano AM; Ramaswamy V
  • Impaired SARS-CoV-2 Variant Neutralization and CD8+ T-cell Responses Following 3 Doses of mRNA Vaccines in Myeloma: Correlation with Breakthrough Infections.
    Blood Cancer Discov Volume: 4 Page(s): 106 - 117
    03/01/2023 Authors: Azeem MI; Nooka AK; Shanmugasundaram U; Cheedarla N; Potdar S; Manalo RJ; Moreno A; Switchenko JM; Cheedarla S; Doxie DB
  • Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis.
    Nat Commun Volume: 14 Page(s): 77
    01/05/2023 Authors: Light N; Layeghifard M; Attery A; Subasri V; Zatzman M; Anderson ND; Hatkar R; Blay S; Chen D; Novokmet A
  • Infantile metastatic ependymoma with a novel molecular profile and favorable outcome to intensive chemotherapy without irradiation: Case-based review.
    Genes Chromosomes Cancer Volume: 62 Page(s): 39 - 46
    01/01/2023 Authors: De Faria FW; Schieffer KM; Pierson CR; Boue DR; LaHaye S; Miller KE; Amayiri N; Koboldt DC; Lichtenberg T; Leraas K
  • Changes in Bone Marrow Tumor and Immune Cells Correlate with Durability of Remissions Following BCMA CAR T Therapy in Myeloma.
    Blood Cancer Discov Volume: 3 Page(s): 490 - 501
    11/02/2022 Authors: Dhodapkar KM; Cohen AD; Kaushal A; Garfall AL; Manalo RJ; Carr AR; McCachren SS; Stadtmauer EA; Lacey SF; Melenhorst JJ
  • Comprehensive Characterization of the Multiple Myeloma Immune Microenvironment Using Integrated scRNA-seq, CyTOF, and CITE-seq Analysis.
    Cancer Res Commun Volume: 2 Page(s): 1255 - 1265
    10/01/2022 Authors: Yao L; Jayasinghe RG; Lee BH; Bhasin SS; Pilcher W; Doxie DB; Gonzalez-Kozlova E; Dasari S; Fiala MA; Pita-Juarez Y
  • Factors influencing outcomes of older children with medulloblastoma over 15years in Peru, a resource-limited setting.
    Pediatr Blood Cancer Volume: 69 Page(s): e29770
    10/01/2022 Authors: Diaz-Coronado RY; Reinecke JB; Stanek JR; Finlay JL; Hernndez Broncano E; Chvez Paredes S; Tunque YM; Heredia Zelaya A; Casavilca Zambrano S; Garca-Corrochano Medina P
  • Determinants of Neutralizing Antibody Response After SARS CoV-2 Vaccination in Patients With Myeloma.
    J Clin Oncol Volume: 40 Page(s): 3057 - 3064
    09/10/2022 Authors: Nooka AK; Shanmugasundaram U; Cheedarla N; Verkerke H; Edara VV; Valanparambil R; Kaufman JL; Hofmeister CC; Joseph NS; Lonial S
  • Association of race/ethnicity with innate immune tumor microenvironment of children with B-acute lymphoblastic leukemia.
    J Immunother Cancer Volume: 10
    06/01/2022 Authors: Gilbert JR; Sabnis HS; Radzievski R; Doxie DB; DeRyckere D; Castellino SM; Dhodapkar K
  • ENRICHMENT OF HIGH-RISK INNATE IMMUNE CELLS IN HISPANIC AND BLACK CHILDREN WITH B-ALL
    Volume: 69
    06/01/2022 Authors: Gilbert J; Sabnis H; Radzievski R; Doxie D; DeRyckere D; Castellino S; Dhodapkar K
  • EANO, SNO and Euracan consensus review on the current management and future development of intracranial germ cell tumors in adolescents and young adults.
    Neuro Oncol Volume: 24 Page(s): 516 - 527
    04/01/2022 Authors: Frappaz D; Dhall G; Murray MJ; Goldman S; Faure Conter C; Allen J; Kortmann RD; Haas-Kogen D; Morana G; Finlay J
  • T cell characteristics associated with toxicity to immune checkpoint blockade in patients with melanoma.
    Nat Med Volume: 28 Page(s): 353 - 362
    02/01/2022 Authors: Lozano AX; Chaudhuri AA; Nene A; Bacchiocchi A; Earland N; Vesely MD; Usmani A; Turner BE; Steen CB; Luca BA
  • Recurrent Wnt medulloblastoma treated with marrow-ablative chemotherapy and autologous hematopoietic progenitor cell rescue: a dual case report and review of the literature.
    Childs Nerv Syst Volume: 38 Page(s): 465 - 472
    02/01/2022 Authors: Harris MK; Shatara M; Funk Z; Stanek J; Bou DR; Jones J; Finlay JL; Abdelbaki MS
  • Epidemiological characteristics and survival outcomes of children with medulloblastoma treated at the National Cancer Institute (INCA) in Rio de Janeiro, Brazil.
    Pediatr Blood Cancer Volume: 69 Page(s): e29274
    01/01/2022 Authors: Oigman G; Osorio DS; Ferman S; Stanek JR; Aversa do Souto A; Christiani MMC; Magalhaes DMA; Finlay JL; Vianna DA
  • Prognostic factors for patients with relapsed central nervous system nongerminomatous germ cell tumors.
    Pediatr Blood Cancer Volume: 69 Page(s): e29365
    01/01/2022 Authors: Abu-Arja MH; Osorio DS; Lassaletta A; Graham RT; Coven SL; Stanek JR; Bouffet E; Finlay JL; Abdelbaki MS
  • Clinically aggressive pediatric spinal ependymoma with novel MYC amplification demonstrates molecular and histopathologic similarity to newly described MYCN-amplified spinal ependymomas.
    Acta Neuropathol Commun Volume: 9 Page(s): 192
    12/11/2021 Authors: Shatara M; Schieffer KM; Klawinski D; Thomas DL; Pierson CR; Sribnick EA; Jones J; Rodriguez DP; Deeg C; Hamelberg E
  • Discovery of clinically relevant fusions in pediatric cancer.
    BMC Genomics Volume: 22 Page(s): 872
    12/04/2021 Authors: LaHaye S; Fitch JR; Voytovich KJ; Herman AC; Kelly BJ; Lammi GE; Arbesfeld JA; Wijeratne S; Franklin SJ; Schieffer KM
  • CORRELATIVE ANALYSIS OF BLOOD AND BIOPSY SAMPLES FROM A CLINICAL TRIAL OF HSP90 INHIBITION IN COMBINATION WITH PEMBROLIZUMAB REVEALS INCREASED INTRATUMORAL MYELOID CELL ACCUMULATION AFTER TREATMENT
    Volume: 9 Page(s): A434 - A434
    11/01/2021 Authors: Herting C; Zhang Y; Doxie D; Ware M; Alese O; Wu C; Akce M; Zaidi M; Ruggieri A; Dhodapkar M
  • Aberrant Extrafollicular B Cells, Immune Dysfunction, Myeloid Inflammation, and MyD88-Mutant Progenitors Precede Waldenstrom Macroglobulinemia.
    Blood Cancer Discov Volume: 2 Page(s): 600 - 615
    11/01/2021 Authors: Kaushal A; Nooka AK; Carr AR; Pendleton KE; Barwick BG; Manalo J; McCachren SS; Gupta VA; Joseph NS; Hofmeister CC
  • Role of MBD3-SOX2 axis in residual myeloma following pomalidomide.
    Leukemia Volume: 35 Page(s): 3319 - 3323
    11/01/2021 Authors: Verma R; Branagan AR; Xu ML; Flavell RA; Dhodapkar KM; Dhodapkar MV
  • Pediatric Gliosarcoma With and Without Neurofibromatosis Type 1: A Whole-exome Comparison of 2 Patients.
    J Pediatr Hematol Oncol Volume: 43 Page(s): e1201 - e1204
    11/01/2021 Authors: Graham RT; Bell EH; Webb A; Zhao Y; Timmers C; Fleming JL; Sells BE; Robison NJ; Palmer JD; Finlay JL
  • Multi-institutional analysis of treatment modalities in basal ganglia and thalamic germinoma.
    Volume: 68 Page(s): e29172
    10/01/2021 Authors: Graham RT; Abu-Arja MH; Stanek JR; Cappellano A; Coleman C; Chi S; Cooney T; Dhall G; Ellen JG; Finlay JL
  • STAT3 inhibitor in combination with irradiation significantly inhibits cell viability, cell migration, invasion and tumorsphere growth of human medulloblastoma cells.
    Cancer Biol Ther Volume: 22 Page(s): 430 - 439
    09/02/2021 Authors: Pan L; Zhang R; Ma L; Pierson CR; Finlay JL; Li C; Lin J
  • Follow-up evaluation of a web-based pediatric brain tumor board in Latin America.
    Pediatr Blood Cancer Volume: 68 Page(s): e29073
    09/01/2021 Authors: Rosabal-Obando M; Osorio DS; Lassaletta A; La Madrid AM; Bartels U; Finlay JL; Qaddoumi I; Rutkowski S; Mynarek M
  • Validated quantitative needs assessment differences in the management of children with central nervous system cancer between Brazil, an upper middle-income country, and the United States of America, a high income country.
    Pediatr Blood Cancer Volume: 68 Page(s): e28958
    06/01/2021 Authors: Fischer AN; Roecker R; Saba da Silva N; Cavalheiro S; Finlay JL; Cappellano A; Osorio DS
  • Molecular classification of a complex structural rearrangement of the RB1 locus in an infant with sporadic, isolated, intracranial, sellar region retinoblastoma.
    Acta Neuropathol Commun Volume: 9 Page(s): 61
    04/07/2021 Authors: Schieffer KM; Feldman AZ; Kautto EA; McGrath S; Miller AR; Hernandez-Gonzalez ME; LaHaye S; Miller KE; Koboldt DC; Brennan P
  • Clinical response to dabrafenib plus trametinib in a pediatric ganglioglioma with BRAF p.T599dup mutation.
    Cold Spring Harb Mol Case Stud Volume: 7
    04/01/2021 Authors: Miller KE; Schieffer KM; Grischow O; Rodriguez DP; Cottrell CE; Leonard JR; Finlay JL; Mardis ER
  • LLL12B, a small molecule STAT3 inhibitor, induces growth arrest, apoptosis, and enhances cisplatin-mediated cytotoxicity in medulloblastoma cells.
    Sci Rep Volume: 11 Page(s): 6517
    03/22/2021 Authors: Chen X; Pan L; Wei J; Zhang R; Yang X; Song J; Bai R-Y; Fu S; Pierson CR; Finlay JL
  • Tandem high-dose influenza vaccination is associated with more durable serologic immunity in patients with plasma cell dyscrasias.
    Blood Adv Volume: 5 Page(s): 1535 - 1539
    03/09/2021 Authors: Branagan AR; Duffy E; Gan G; Li F; Foster C; Verma R; Zhang L; Parker TL; Seropian S; Cooper DL
  • Evaluation of the Pediatric Neuro-Oncology Resources Available in Chile.
    JCO Glob Oncol Volume: 7 Page(s): 425 - 434
    03/01/2021 Authors: Abu-Arja MH; Rojas Del Ro N; Morales La Madrid A; Lassaletta A; Coven SL; Moreno R; Valero M; Perez V; Espinoza F; Fernandez E
  • YAP1-FAM118B Fusion Defines a Rare Subset of Childhood and Young Adulthood Meningiomas.
    Am J Surg Pathol Volume: 45 Page(s): 329 - 340
    03/01/2021 Authors: Schieffer KM; Agarwal V; LaHaye S; Miller KE; Koboldt DC; Lichtenberg T; Leraas K; Brennan P; Kelly BJ; Crist E
  • Venous thromboembolism in children with central nervous system tumors: Comparison of an institutional cohort to a national administrative database.
    Pediatr Blood Cancer Volume: 68 Page(s): e28846
    03/01/2021 Authors: Graham RT; Coven SL; Stanek JR; Folta A; Hollingsworth EW; Finlay JL; Kumar R
  • Molecular insights into malignant progression of atypical choroid plexus papilloma.
    Cold Spring Harb Mol Case Stud Volume: 7
    02/01/2021 Authors: Yankelevich M; Finlay JL; Gorsi H; Kupsky W; Boue DR; Koschmann CJ; Kumar-Sinha C; Mody R
  • Brain biomarkers and neuropsychological outcomes of pediatric posterior fossa brain tumor survivors treated with surgical resection with or without adjuvant chemotherapy.
    Pediatr Blood Cancer Volume: 68 Page(s): e28817
    02/01/2021 Authors: Baron Nelson MC; O'Neil SH; Tanedo J; Dhanani S; Malvar J; Nuez C; Nelson MD; Tamrazi B; Finlay JL; Rajagopalan V
  • Viral Immunity and Vaccines in Hematologic Malignancies: Implications for COVID-19.
    Blood Cancer Discov Volume: 2 Page(s): 9 - 12
    01/01/2021 Authors: Dhodapkar MV; Dhodapkar KM; Ahmed R
  • Co-evolution of Immune Response in Multiple Myeloma: Implications for Immune Prevention.
    Front Immunol Volume: 12 Page(s): 632564
    01/01/2021 Authors: McCachren SS; Dhodapkar KM; Dhodapkar MV
  • Excellent outcome of young children with nodular desmoplastic medulloblastoma treated on "Head Start" III: a multi-institutional, prospective clinical trial.
    Neuro Oncol Volume: 22 Page(s): 1862 - 1872
    12/18/2020 Authors: Dhall G; O'Neil SH; Ji L; Haley K; Whitaker AM; Nelson MD; Gilles F; Gardner SL; Allen JC; Cornelius AS
  • SITC cancer immunotherapy resource document: a compass in the land of biomarker discovery.
    J Immunother Cancer Volume: 8
    12/01/2020 Authors: Hu-Lieskovan S; Bhaumik S; Dhodapkar K; Grivel J-CJB; Gupta S; Hanks BA; Janetzki S; Kleen TO; Koguchi Y; Lund AW
  • Characterizing temporal genomic heterogeneity in pediatric low-grade gliomas.
    Acta Neuropathol Commun Volume: 8 Page(s): 182
    11/05/2020 Authors: Lazow MA; Hoffman L; Schafer A; Osorio DS; Bou DR; Rush S; Wright E; Lane A; DeWire-Schottmiller MD; Smolarek T
  • INVESTIGATING THE CLINICAL SAFETY, EFFICACY, AND IMMUNE MODULATION OF COMBINED XL888 AND PEMBROLIZUMAB IN METASTATIC GASTROINTESTINAL MALIGNANCIES
    Volume: 8 Page(s): A202 - A203
    11/01/2020 Authors: Herting C; Zhang Y; Doxie D; Farren M; Ware M; Alese O; Wu C; Shaib W; Akce M; Zaidi M
  • Risk-associated alterations in marrow T cells in pediatric leukemia.
    JCI Insight Volume: 5
    08/20/2020 Authors: Bailur JK; McCachren SS; Pendleton K; Vasquez JC; Lim HS; Duffy A; Doxie DB; Kaushal A; Foster C; DeRyckere D
  • Subtype and grade-dependent spatial heterogeneity of T-cell infiltration in pediatric glioma.
    J Immunother Cancer Volume: 8
    08/01/2020 Authors: Robinson MH; Vasquez J; Kaushal A; MacDonald TJ; Velzquez Vega JE; Schniederjan M; Dhodapkar K
  • Exploring DNA Methylation for Prognosis and Analyzing the Tumor Microenvironment in Pleomorphic Xanthoastrocytoma.
    J Neuropathol Exp Neurol Volume: 79 Page(s): 880 - 890
    08/01/2020 Authors: Tang K; Kurland D; Vasudevaraja V; Serrano J; Delorenzo M; Radmanesh A; Thomas C; Spino M; Gardner S; Allen JC
  • Meta-Analysis of Treatment Modalities in Metastatic Atypical Teratoid/Rhabdoid Tumors in Children.
    Pediatr Neurol Volume: 108 Page(s): 106 - 112
    07/01/2020 Authors: Underiner RM; Eltobgy M; Stanek JR; Finlay JL; AbdelBaki MS
  • Differential effects of PD-L1 versus PD-1 blockade on myeloid inflammation in human cancer.
    JCI Insight Volume: 5
    06/18/2020 Authors: Bar N; Costa F; Das R; Duffy A; Samur M; McCachren S; Gettinger SN; Neparidze N; Parker TL; Bailur JK
  • Tissue-resident memory-like T cells in tumor immunity: Clinical implications.
    Semin Immunol Volume: 49 Page(s): 101415
    06/01/2020 Authors: Dhodapkar MV; Dhodapkar KM
  • Pineoblastoma in children less than six years of age: The Head Start I, II, and III experience.
    Pediatr Blood Cancer Volume: 67 Page(s): e28252
    06/01/2020 Authors: Abdelbaki MS; Abu-Arja MH; Davidson TB; Fangusaro JR; Stanek JR; Dunkel IJ; Dhall G; Gardner SL; Finlay JL
  • Np73/ETS2 complex drives glioblastoma pathogenesis- targeting downstream mediators by rebastinib prolongs survival in preclinical models of glioblastoma.
    Neuro Oncol Volume: 22 Page(s): 345 - 356
    03/05/2020 Authors: Cam M; Charan M; Welker AM; Dravid P; Studebaker AW; Leonard JR; Pierson CR; Nakano I; Beattie CE; Hwang EI
  • Outcomes of BRAF V600E Pediatric Gliomas Treated With Targeted BRAF Inhibition.
    Volume: 4
    01/01/2020 Authors: Nobre L; Zapotocky M; Ramaswamy V; Ryall S; Bennett J; Alderete D; Balaguer Guill J; Baroni L; Bartels U; Bavle A
  • Editorial: HIV and Cancer Immunotherapy: Similar Challenges and Converging Approaches.
    Front Immunol Volume: 11 Page(s): 519
    01/01/2020 Authors: Paiardini M; Dhodapkar K; Harper J; Deeks SG; Ahmed R
  • Autoimmune complications of cancer immunotherapy.
    Curr Opin Immunol Volume: 61 Page(s): 54 - 59
    12/01/2019 Authors: Dhodapkar KM
  • Early alterations in stem-like/resident T cells, innate and myeloid cells in the bone marrow in preneoplastic gammopathy.
    JCI Insight Volume: 5
    04/23/2019 Authors: Bailur JK; McCachren SS; Doxie DB; Shrestha M; Pendleton K; Nooka AK; Neparidze N; Parker TL; Bar N; Kaufman JL
  • Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma.
    JCI Insight Volume: 4
    02/21/2019 Authors: Garfall AL; Stadtmauer EA; Hwang W-T; Lacey SF; Melenhorst JJ; Krevvata M; Carroll MP; Matsui WH; Wang Q; Dhodapkar MV
  • Moving Immunoprevention Beyond Virally Mediated Malignancies: Do We Need to Link It to Early Detection?
    Front Immunol Volume: 10 Page(s): 2385
    01/01/2019 Authors: Dhodapkar MV; Dhodapkar KM
  • Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma.
    JCI Insight Volume: 3
    04/19/2018 Authors: Garfall AL; Stadtmauer EA; Hwang W-T; Lacey SF; Melenhorst JJ; Krevvata M; Carroll MP; Matsui WH; Wang Q; Dhodapkar MV
  • Blocking interleukin-6 signaling inhibits cell viability/proliferation, glycolysis, and colony forming activity of human medulloblastoma cells.
    Int J Oncol Volume: 52 Page(s): 571 - 578
    02/01/2018 Authors: Chen X; Wei J; Li C; Pierson CR; Finlay JL; Lin J
  • Early B cell changes predict autoimmunity following combination immune checkpoint blockade.
    J Clin Invest Volume: 128 Page(s): 715 - 720
    02/01/2018 Authors: Das R; Bar N; Ferreira M; Newman AM; Zhang L; Bailur JK; Bacchiocchi A; Kluger H; Wei W; Halaban R
  • Checkpoint Inhibition in Myeloma: Opportunities and Challenges.
    Front Immunol Volume: 9 Page(s): 2204
    01/01/2018 Authors: Costa F; Das R; Kini Bailur J; Dhodapkar K; Dhodapkar MV
  • Role of Tissue-Resident Memory in Intra-Tumor Heterogeneity and Response to Immune Checkpoint Blockade.
    Front Immunol Volume: 9 Page(s): 1655
    01/01/2018 Authors: Dhodapkar KM
  • Early Enrichment and Subsequent Dysfunction of Marrow ILC Subsets in Monoclonal Gammopathy: Target for IMiD Therapy
    Volume: 130
    12/07/2017 Authors: Bailur JK; Mehta S; Zhang L; Neparidze N; Parker TL; Bar N; Anderson T; Xu M; Dhodapkar K; Dhodapkar MV
  • Changes in bone marrow innate lymphoid cell subsets in monoclonal gammopathy: target for IMiD therapy.
    Blood Adv Volume: 1 Page(s): 2343 - 2347
    11/28/2017 Authors: Kini Bailur J; Mehta S; Zhang L; Neparidze N; Parker T; Bar N; Anderson T; Xu ML; Dhodapkar KM; Dhodapkar MV
  • SOX2 immunity and tissue resident memory in children and young adults with glioma.
    J Neurooncol Volume: 134 Page(s): 41 - 53
    08/01/2017 Authors: Vasquez JC; Huttner A; Zhang L; Marks A; Chan A; Baehring JM; Kahle KT; Dhodapkar KM
  • SOX2 as a target for immunotherapy of pediatric gliomas
    Volume: 35
    05/20/2017 Authors: Vasquez J; Huttner A; Zhang L; Marks A; Chan A; Baehring JM; Kahle K; Dhodapkar KM
  • Long-term neuropsychological follow-up of young children with medulloblastoma treated with sequential high-dose chemotherapy and irradiation sparing approach.
    J Neurooncol Volume: 133 Page(s): 119 - 128
    05/01/2017 Authors: Fay-McClymont TB; Ploetz DM; Mabbott D; Walsh K; Smith A; Chi SN; Wells E; Madden J; Margol A; Finlay J
  • Distinct dominant T-cell receptors with a tissue resident memory phenotype in individual melanoma metastases.
    Volume: 35
    03/01/2017 Authors: Dhodapkar KM; Boddupalli CS; Bar N; Kadaveru K; Krauthammer M; Pornputtapong N; Mai Z; Ariyan S; Narayan D; Kluger HM
  • Interlesional diversity of T cell receptors in melanoma with immune checkpoints enriched in tissue-resident memory T cells.
    JCI Insight Volume: 1 Page(s): e88955
    12/22/2016 Authors: Boddupalli CS; Bar N; Kadaveru K; Krauthammer M; Pornputtapong N; Mai Z; Ariyan S; Narayan D; Kluger H; Deng Y
  • ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells.
    J Clin Invest Volume: 126 Page(s): 3905 - 3916
    10/03/2016 Authors: Boddupalli CS; Nair S; Gray SM; Nowyhed HN; Verma R; Gibson JA; Abraham C; Narayan D; Vasquez J; Hedrick CC
  • Harnessing shared antigens and T-cell receptors in cancer: Opportunities and challenges.
    Proc Natl Acad Sci U S A Volume: 113 Page(s): 7944 - 7945
    07/19/2016 Authors: Dhodapkar K; Dhodapkar M
  • Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC.
    Oncoimmunology Volume: 5 Page(s): e1071008
    04/01/2016 Authors: Besse B; Charrier M; Lapierre V; Dansin E; Lantz O; Planchard D; Le Chevalier T; Livartoski A; Barlesi F; Laplanche A
  • Identification of a Cereblon-Independent Protein Degradation Pathway in Residual Myeloma Cells Treated with Immunomodulatory Drugs
    Volume: 126
    12/03/2015 Authors: Verma R; Mai Z; Xu M; Zhang L; Dhodapkar K; Dhodapkar MV
  • Prospective analysis of antigen-specific immunity, stem-cell antigens, and immune checkpoints in monoclonal gammopathy.
    Blood Volume: 126 Page(s): 2475 - 2478
    11/26/2015 Authors: Dhodapkar MV; Sexton R; Das R; Dhodapkar KM; Zhang L; Sundaram R; Soni S; Crowley JJ; Orlowski RZ; Barlogie B
  • Immune Modulation in Hematologic Malignancies.
    Semin Oncol Volume: 42 Page(s): 617 - 625
    08/01/2015 Authors: Dhodapkar MV; Dhodapkar KM
  • Comparison of pomalidomide dosing strategies in lenalidomide-refractory myeloma: Impact on clinical outcome, immune activation and cereblon targets
    Volume: 75
    08/01/2015 Authors: Das R; Sehgai K; Zhang L; Verma R; Deng Y; Kocoglu M; Vasquez J; Koduru S; Ren Y; Wang M
  • Combination therapy with anti-CTLA4 and anti-PD1 leads to distinct immunologic changes in-vivo
    Volume: 75
    07/15/2015 Authors: Das R; Verma R; Sznol M; Boddupalli CS; Gettinger S; Kluger H; Dhodapkar M; Dhodapkar K
  • Clinical and pharmacodynamic analysis of pomalidomide dosing strategies in myeloma: impact of immune activation and cereblon targets.
    Blood Volume: 125 Page(s): 4042 - 4051
    06/25/2015 Authors: Sehgal K; Das R; Zhang L; Verma R; Deng Y; Kocoglu M; Vasquez J; Koduru S; Ren Y; Wang M
  • SOX2 EXPRESSION IN PEDIATRIC BRAIN TUMORS: A POTENTIAL NEW TARGET FOR IMMUNOTHERAPY
    Volume: 62 Page(s): 106 - 106
    06/01/2015 Authors: Vasquez J; Huttner A; Dhodapkar K
  • Combination therapy with anti-CTLA-4 and anti-PD-1 leads to distinct immunologic changes in vivo.
    J Immunol Volume: 194 Page(s): 950 - 959
    02/01/2015 Authors: Das R; Verma R; Sznol M; Boddupalli CS; Gettinger SN; Kluger H; Callahan M; Wolchok JD; Halaban R; Dhodapkar MV
  • Targeting human dendritic cells in situ to improve vaccines.
    Immunol Lett Volume: 162 Page(s): 59 - 67
    11/01/2014 Authors: Sehgal K; Dhodapkar KM; Dhodapkar MV
  • Nanoparticle-mediated combinatorial targeting of multiple human dendritic cell (DC) subsets leads to enhanced T cell activation via IL-15-dependent DC crosstalk.
    J Immunol Volume: 193 Page(s): 2297 - 2305
    09/01/2014 Authors: Sehgal K; Ragheb R; Fahmy TM; Dhodapkar MV; Dhodapkar KM
  • Recent advances and new opportunities for targeting human dendritic cells in situ.
    Oncoimmunology Volume: 3 Page(s): e954832
    01/01/2014 Authors: Dhodapkar MV; Dhodapkar KM
  • Both Intermittent and Continuous Dosing Regimens Of Pomalidomide Mediate Broad Activation Of Innate and Adaptive Immunity In Relapsed/Refractory Myeloma: Results Of A Phase II Randomized Trial
    Volume: 122
    11/15/2013 Authors: Dhodapkar K; Zhang L; Verma R; Sehgal K; Kocoglu MH; Dhodapkar MV
  • Plasmacytoid dendritic cells, interferon signaling, and FcR contribute to pathogenesis and therapeutic response in childhood immune thrombocytopenia.
    Sci Transl Med Volume: 5 Page(s): 193ra89
    07/10/2013 Authors: Sehgal K; Guo X; Koduru S; Shah A; Lin A; Yan X; Dhodapkar KM
  • SOX2-specific adaptive immunity and response to immunotherapy in non-small cell lung cancer.
    Oncoimmunology Volume: 2 Page(s): e25205
    07/01/2013 Authors: Dhodapkar KM; Gettinger SN; Das R; Zebroski H; Dhodapkar MV
  • Clinical regressions and broad immune activation following combination therapy targeting human NKT cells in myeloma.
    Blood Volume: 121 Page(s): 423 - 430
    01/17/2013 Authors: Richter J; Neparidze N; Zhang L; Nair S; Monesmith T; Sundaram R; Miesowicz F; Dhodapkar KM; Dhodapkar MV
  • High SOX2 levels predict better outcome in non-small cell lung carcinomas.
    PLoS One Volume: 8 Page(s): e61427
    01/01/2013 Authors: Velcheti V; Schalper K; Yao X; Cheng H; Kocoglu M; Dhodapkar K; Deng Y; Gettinger S; Rimm DL
  • Central and overlapping role of Cathepsin B and inflammasome adaptor ASC in antigen presenting function of human dendritic cells.
    Hum Immunol Volume: 73 Page(s): 871 - 878
    09/01/2012 Authors: Guo X; Dhodapkar KM
  • Induction of activation-induced cytidine deaminase (AID) by dendritic cells leads to genomic instability in human myeloma
    Volume: 72
    04/15/2012 Authors: Koduru S; Wong E; Strowig T; Sundaram R; Zhang L; Strout MP; Flavell RA; Schatz DG; Dhodapkar KM; Dhodapkar MV
  • Dendritic cell-mediated activation-induced cytidine deaminase (AID)-dependent induction of genomic instability in human myeloma.
    Blood Volume: 119 Page(s): 2302 - 2309
    03/08/2012 Authors: Koduru S; Wong E; Strowig T; Sundaram R; Zhang L; Strout MP; Flavell RA; Schatz DG; Dhodapkar KM; Dhodapkar MV
  • Pluripotency genes as targets for cancer prevention
    Volume: 71
    04/15/2011 Authors: Dhodapkar K
  • Spontaneous and therapy-induced immunity to pluripotency genes in humans: clinical implications, opportunities and challenges.
    Cancer Immunol Immunother Volume: 60 Page(s): 413 - 418
    03/01/2011 Authors: Dhodapkar MV; Dhodapkar KM
  • Vaccines targeting cancer stem cells: are they within reach?
    Cancer J Volume: 17 Page(s): 397 - 402
    01/01/2011 Authors: Dhodapkar MV; Dhodapkar KM
  • Natural immunity to pluripotency antigen OCT4 in humans.
    Proc Natl Acad Sci U S A Volume: 107 Page(s): 8718 - 8723
    05/11/2010 Authors: Dhodapkar KM; Feldman D; Matthews P; Radfar S; Pickering R; Turkula S; Zebroski H; Dhodapkar MV
  • FC gamma R Mediated Regulation of Adaptive Immunity: Implications for Antibody Therapies
    Volume: 32 Page(s): 993 - 993
    11/01/2009 Authors: Dhodapkar M; Dhodapkar K
  • Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myeloma.
    Blood Volume: 112 Page(s): 2878 - 2885
    10/01/2008 Authors: Dhodapkar KM; Barbuto S; Matthews P; Kukreja A; Mazumder A; Vesole D; Jagannath S; Dhodapkar MV
  • Role of chaperones and FcgammaR in immunogenic death.
    Curr Opin Immunol Volume: 20 Page(s): 512 - 517
    10/01/2008 Authors: Dhodapkar MV; Dhodapkar KM; Li Z
  • Interactions of tumor cells with dendritic cells: balancing immunity and tolerance.
    Cell Death Differ Volume: 15 Page(s): 39 - 50
    01/01/2008 Authors: Dhodapkar MV; Dhodapkar KM; Palucka AK
  • Enhanced T-cell responses to glioma cells coated with the anti-EGF receptor antibody and targeted to activating FcgammaRs on human dendritic cells.
    J Immunother Volume: 31 Page(s): 113 - 120
    01/01/2008 Authors: Banerjee D; Matthews P; Matayeva E; Kaufman JL; Steinman RM; Dhodapkar KM
  • Selective blockade of the inhibitory Fcgamma receptor (FcgammaRIIB) in human dendritic cells and monocytes induces a type I interferon response program.
    J Exp Med Volume: 204 Page(s): 1359 - 1369
    06/11/2007 Authors: Dhodapkar KM; Banerjee D; Connolly J; Kukreja A; Matayeva E; Veri MC; Ravetch JV; Steinman RM; Dhodapkar MV
  • Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients.
    Blood Volume: 108 Page(s): 2655 - 2661
    10/15/2006 Authors: Banerjee DK; Dhodapkar MV; Matayeva E; Steinman RM; Dhodapkar KM
  • Enhancement of clonogenicity of human multiple myeloma by dendritic cells.
    J Exp Med Volume: 203 Page(s): 1859 - 1865
    08/07/2006 Authors: Kukreja A; Hutchinson A; Dhodapkar K; Mazumder A; Vesole D; Angitapalli R; Jagannath S; Dhodapkar MV
  • Harnessing the immune system against human glioma.
    Ann N Y Acad Sci Volume: 1062 Page(s): 13 - 21
    12/01/2005 Authors: Dhodapkar KM; Banerjee D; Steinman RM
  • Recruiting dendritic cells to improve antibody therapy of cancer.
    Proc Natl Acad Sci U S A Volume: 102 Page(s): 6243 - 6244
    05/03/2005 Authors: Dhodapkar KM; Dhodapkar MV
  • Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells.
    Proc Natl Acad Sci U S A Volume: 102 Page(s): 2910 - 2915
    02/22/2005 Authors: Dhodapkar KM; Kaufman JL; Ehlers M; Banerjee DK; Bonvini E; Koenig S; Steinman RM; Ravetch JV; Dhodapkar MV
  • Invariant natural killer T cells are preserved in patients with glioma and exhibit antitumor lytic activity following dendritic cell-mediated expansion.
    Int J Cancer Volume: 109 Page(s): 893 - 899
    05/10/2004 Authors: Dhodapkar KM; Cirignano B; Chamian F; Zagzag D; Miller DC; Finlay JL; Steinman RM
  • A reversible defect in natural killer T cell function characterizes the progression of premalignant to malignant multiple myeloma.
    J Exp Med Volume: 197 Page(s): 1667 - 1676
    06/16/2003 Authors: Dhodapkar MV; Geller MD; Chang DH; Shimizu K; Fujii S-I; Dhodapkar KM; Krasovsky J
  • Antitumor monoclonal antibodies enhance cross-presentation ofcCellular antigens and the generation of myeloma-specific killer T cells by dendritic cells.
    J Exp Med Volume: 195 Page(s): 125 - 133
    01/07/2002 Authors: Dhodapkar KM; Krasovsky J; Williamson B; Dhodapkar MV
  • Preliminary results of dose intensive pre-irradiation chemotherapy in patients older than 10 years of age with high risk medulloblastoma and supratentorial primitive neuroectodermal tumors.
    Med Pediatr Oncol Volume: 38 Page(s): 47 - 48
    01/01/2002 Authors: Dhodapkar K; Dunkel IJ; Gardner S; Sapp M; Thoron L; Finlay J
  • Anti-tumor monoclonal antibodies enhance cross presentation of cellular antigens and generation of tumor specific killer cells by dendritic cells.
    Volume: 98 Page(s): 33B - 33B
    11/16/2001 Authors: Dhodapkar KM; Krasovsky J; Williamson B; Dhodapkar MV
  • Differential expression of the cell-adhesion molecule Nr-CAM in hyperplastic and neoplastic human pancreatic tissue.
    Hum Pathol Volume: 32 Page(s): 396 - 400
    04/01/2001 Authors: Dhodapkar KM; Friedlander D; Scholes J; Grumet M
  • Treatment of hemolytic disease of the newborn caused by anti-Kell antibody with recombinant erythropoietin.
    J Pediatr Hematol Oncol Volume: 23 Page(s): 69 - 70
    01/01/2001 Authors: Dhodapkar KM; Blei F
  • Purpura fulminans caused by group A beta-hemolytic Streptococcus sepsis.
    J Pediatr Volume: 137 Page(s): 562 - 567
    10/01/2000 Authors: Dhodapkar K; Corbacioglu S; Chang MW; Karpatkin M; DiMichele D
  • Leuconostoc bacteremia in an infant with short-gut syndrome: case report and literature review.
    Mayo Clin Proc Volume: 71 Page(s): 1171 - 1174
    12/01/1996 Authors: Dhodapkar KM; Henry NK
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