Kenneth Newell MD/PhD
Overview
Dr. Newell came to Emory from the University of Chicago, where he had been serving as director of kidney and pancreas transplantation. Prior to joining the faculty of UChicago, he earned his PhD in immunology and completed an abdominal transplantation fellowship at the institution. He received his medical degree from the University of Michigan and completed his general surgery residency at Loyola Medical Center in Illinois.
Dr. Newell served as director of Emory's living donor kidney transplant program from 2003-2014 and established Emory's unrelated paired donor kidney exchange program in 2007. His various research pursuits have included optimizing belatacept as an immunosuppressant in renal transplantation, identification and mechanistic investigations of tolerant kidney transplant patients, and the development of transplant strategies uniquely responsive to the needs of children
Dr. Newell served as president of the American Society of Transplantation from 2014-2015, was an at large member of the OPTN/UNOS Vascularized Composite Allograft Transplant (VCA) Committee from 2013-2016, and chaired the Mechanistic Studies Subcommittee of the Clinical Trials in Organ Transplantation program of the NIH.
Academic Appointment
- Professor of Surgery with Tenure, Department of Surgery, Emory University School of Medicine
Education
Degrees
- PhD from University of Chicago
- MD from University of Michigan
- BA from Kalamazoo College
Research
Focus
- The aims of ongoing studies in my laboratory are to define the mechanisms responsible for the rejection of transplanted organs. Murine transplant models are utilized to characterize the response of T cells to alloantigens and determine how antigen presentation and T cell trafficking are regulated. Based on an understanding of these mechanisms, therapeutic interventions are proposed and tested.
Publications
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Early Post-Transplant Renal Recovery Trajectory and Trajectory Velocity Functions Are Predictors of Estimated GFR at 1 Year: A Functional Data Analysis Approach.
Clin Transplant Volume: 39 Page(s): e70119
03/01/2025 Authors: Magua W; Cristea O; Eichenberger EM; Karadkhele GM; Morris AA; Newell K; Rickert JB; Larsen CP -
Comparing the prognostic performance of iBOX and biopsy-proven acute rejection for long-term kidney graft survival.
Am J Transplant Volume: 24 Page(s): 1784 - 1793
10/01/2024 Authors: Klein A; Kosinski L; Loupy A; Frey E; Stegall M; Helanter I; Newell K; Meier-Kriesche H-U; Mannon RB; Fitzsimmons WE -
Qualifying a novel clinical trial endpoint (iBOX) predictive of long-term kidney transplant outcomes.
Am J Transplant Volume: 23 Page(s): 1496 - 1506
10/01/2023 Authors: Klein A; Loupy A; Stegall M; Helanter I; Kosinski L; Frey E; Aubert O; Divard G; Newell K; Meier-Kriesche H-U -
Demystifying tolerance.
Am J Transplant Volume: 23 Page(s): 1286 - 1287
09/01/2023 Authors: Newell KA -
Scope and Consistency of Cancer Outcomes Reported in Randomized Trials in Kidney Transplant Recipients.
Kidney Int Rep Volume: 8 Page(s): 274 - 281
02/01/2023 Authors: Au EH; Wong G; Tong A; Teixeira-Pinto A; van Zwieten A; Dobrijevic E; Ahn C; Blosser CD; Davidson B; Francis A -
Qualifying a Novel Clinical Trial Endpoint (iBOX) Predictive of Long-Term Kidney Transplant Outcomes.
Transpl Int Volume: 36 Page(s): 11951
01/01/2023 Authors: Klein A; Loupy A; Stegall M; Helanter I; Kosinski L; Frey E; Aubert O; Divard G; Newell K; Meier-Kriesche H-U -
Infliximab Induction Lacks Efficacy and Increases BK Virus Infection in Deceased Donor Kidney Transplant Recipients: Results of the CTOT-19 Trial.
J Am Soc Nephrol Volume: 34 Page(s): 145 - 159
01/01/2023 Authors: Hricik DE; Armstrong B; Alhamad T; Brennan DC; Bromberg JS; Bunnapradist S; Chandran S; Fairchild RL; Foley DP; Formica R -
Impact of belatacept and tacrolimus on cytomegalovirus viral load control and relapse in moderate and high-risk cytomegalovirus serostatus kidney transplant recipients.
Transpl Infect Dis Volume: 24 Page(s): e13983
12/01/2022 Authors: Magua W; Johnson AC; Karadkhele GM; Badell IR; Vasanth P; Mehta AK; Easley KA; Newell KA; Rickert JB; Larsen CP -
Great expectations.
Am J Transplant Volume: 22 Page(s): 1735 - 1736
07/01/2022 Authors: Newell KA; Larsen CP -
Outcomes of Living Kidney Donor Candidate Evaluations in the Living Donor Collective Pilot Registry.
Transplant Direct Volume: 7 Page(s): e689
05/01/2021 Authors: Kasiske BL; Ahn YS; Conboy M; Dew MA; Folken C; Levan M; Israni AK; Lentine KL; Matas AJ; Newell KA -
The Importance of Bringing Transplantation Tolerance to the Clinic.
Transplantation Volume: 105 Page(s): 935 - 940
05/01/2021 Authors: Cosimi AB; Ascher NL; Emond JC; Kaufman DB; Madsen JC; Miller J; Monaco AP; Montgomery RA; Newell KA; Snchez-Fueyo A -
Association Between APOL1 Genotype and Kidney Diseases and Annual Kidney Function Change: A Systematic Review and Meta-Analysis of the Prospective Studies.
Int J Nephrol Renovasc Dis Volume: 14 Page(s): 97 - 104
01/01/2021 Authors: Jagannathan R; Rajagopalan K; Hogan J; Hart A; Newell KA; Pastan SO; Patzer RE -
Avoidance of CNI and steroids using belatacept-Results of the Clinical Trials in Organ Transplantation 16 trial.
Am J Transplant Volume: 20 Page(s): 3599 - 3608
12/01/2020 Authors: Mannon RB; Armstrong B; Stock PG; Mehta AK; Farris AB; Watson N; Morrison Y; Sarwal M; Sigdel T; Bridges N -
Challenges of calcineurin inhibitor withdrawal following combined pancreas and kidney transplantation: Results of a prospective, randomized clinical trial.
Am J Transplant Volume: 20 Page(s): 1668 - 1678
06/01/2020 Authors: Stock PG; Mannon RB; Armstrong B; Watson N; Ikle D; Robien MA; Morrison Y; Odorico J; Fridell J; Mehta AK -
APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO): DesignandRationale.
Kidney Int Rep Volume: 5 Page(s): 278 - 288
03/01/2020 Authors: Freedman BI; Moxey-Mims MM; Alexander AA; Astor BC; Birdwell KA; Bowden DW; Bowen G; Bromberg J; Craven TE; Dadhania DM -
ESKD Risk in Living Kidney Donors "Like Me".
Clin J Am Soc Nephrol Volume: 14 Page(s): 970 - 971
07/05/2019 Authors: Newell KA; Formica RN -
Unique Gene Expression Signatures in Urine Distinguish T Cell Mediated Acute Rejection from BK Virus Nephropathy in Kidney Transplant Patients.
Volume: 19 Page(s): 503 - 503
04/01/2019 Authors: Keslar KS; Xu W; Zmijewska AA; Newell KA; Friedewald JJ; Abecassis MI; Heeger PS; Bromberg JS; Mannon RB; Fairchild RL -
The importance of drug safety and tolerability in the development of new immunosuppressive therapy for transplant recipients: The Transplant Therapeutics Consortium's position statement.
Am J Transplant Volume: 19 Page(s): 625 - 632
03/01/2019 Authors: Stegall MD; Troy Somerville K; Everly MJ; Mannon RB; Gaber AO; First MR; Agashivala N; Perez V; Newell KA; Morris RE -
Current opinions in organ allocation.
Am J Transplant Volume: 18 Page(s): 2625 - 2634
11/01/2018 Authors: By the Contributors to the C4 Article (Appendix 1) -
Meeting report of the STAR-Sensitization in Transplantation Assessment of Risk: Nave Abdominal Transplant Organ subgroup focus on kidney transplantation.
Am J Transplant Volume: 18 Page(s): 2120 - 2134
09/01/2018 Authors: Mannon RB; Askar M; Jackson AM; Newell K; Mengel M -
Sensitization in Transplantation: Assessment of Risk (STAR) 2017 Working Group Meeting Report.
Am J Transplant Volume: 18 Page(s): 1604 - 1614
07/01/2018 Authors: Tambur AR; Campbell P; Claas FH; Feng S; Gebel HM; Jackson AM; Mannon RB; Reed EF; Tinckam K; Askar M -
Challenges in Calcineurin Inhibitor (CNI) Withdrawal in Conjunction with Co-Stimulation Blockade in Simultaneous Pancreas and Kidney Transplant (SPK)
Volume: 102 Page(s): S237 - S238
07/01/2018 Authors: Stock PG; Mannon RB; Armstrong B; Watson N; Ikle D; Robian M; Morrison Y; Odorico J; Fridell J; Ward C -
Unique Gene Expression Signatures in Urine Distinguish BK Virus Nephropathy from Acute Rejection in Kidney Transplant Patients with Graft Dysfunction.
Volume: 18 Page(s): 422 - 422
06/01/2018 Authors: Keslar K; Gotwald P; Xu W; Zmijewska A; Chen J; Newell K; Heeger P; Bromberg J; Mannon R; Fairchild R -
Biomarkers of operational tolerance following kidney transplantation - The immune tolerance network studies of spontaneously tolerant kidney transplant recipients.
Hum Immunol Volume: 79 Page(s): 380 - 387
05/01/2018 Authors: Newell KA; Adams AB; Turka LA -
Analysis of Biomarkers Within the Initial 2 Years Posttransplant and 5-Year Kidney Transplant Outcomes: Results From Clinical Trials in Organ Transplantation-17.
Transplantation Volume: 102 Page(s): 673 - 680
04/01/2018 Authors: Faddoul G; Nadkarni GN; Bridges ND; Goebel J; Hricik DE; Formica R; Menon MC; Morrison Y; Murphy B; Newell K -
Reply to Christakoudi and Hernandez-Fuentes: We agree-Let's move on.
Am J Transplant Volume: 18 Page(s): 273
01/01/2018 Authors: Asare A; Kanaparthi S; Lim N; Newell KA; Turka LA -
The Living Donor Collective: A Scientific Registry for Living Donors.
Am J Transplant Volume: 17 Page(s): 3040 - 3048
12/01/2017 Authors: Kasiske BL; Asrani SK; Dew MA; Henderson ML; Henrich C; Humar A; Israni AK; Lentine KL; Matas AJ; Newell KA -
Belatacept Combined With Transient Calcineurin Inhibitor Therapy Prevents Rejection and Promotes Improved Long-Term Renal Allograft Function.
Am J Transplant Volume: 17 Page(s): 2922 - 2936
11/01/2017 Authors: Adams AB; Goldstein J; Garrett C; Zhang R; Patzer RE; Newell KA; Turgeon NA; Chami AS; Guasch A; Kirk AD -
Lessons Learned: Early Termination of a Randomized Trial of Calcineurin Inhibitor and Corticosteroid Avoidance Using Belatacept.
Am J Transplant Volume: 17 Page(s): 2712 - 2719
10/01/2017 Authors: Newell KA; Mehta AK; Larsen CP; Stock PG; Farris AB; Mehta SG; Ikle D; Armstrong B; Morrison Y; Bridges N -
B Cell Receptor Genes Associated With Tolerance Identify a Cohort of Immunosuppressed Patients With Improved Renal Allograft Graft Function.
Am J Transplant Volume: 17 Page(s): 2627 - 2639
10/01/2017 Authors: Asare A; Kanaparthi S; Lim N; Phippard D; Vincenti F; Friedewald J; Pavlakis M; Poggio E; Heeger P; Mannon R -
A COMPOSITE SCORE ASSOCIATED WITH SPONTANEOUS OPERATIONAL TOLERANCE IN KIDNEY TRANSPLANT RECIPIENTS
Volume: 30 Page(s): 272 - 272
09/01/2017 Authors: Danger R; Chesneau M; Paul C; Guerif P; Durand M; Newell KA; Kanaparthi S; Turka LA; Soulillou J-P; Houlgatte R -
Alloimmunity But Not Viral Immunity Promotes Allograft Loss in a Mouse Model of Polyomavirus-Associated Allograft Injury.
Transplant Direct Volume: 3 Page(s): e161
06/01/2017 Authors: Kim SC; Wang J; Dong Y; Mathews DV; Albrecht JA; Breeden CP; Farris AB; Lukacher AE; Ford ML; Newell KA -
A composite score associated with spontaneous operational tolerance in kidney transplant recipients.
Kidney Int Volume: 91 Page(s): 1473 - 1481
06/01/2017 Authors: Danger R; Chesneau M; Paul C; Gurif P; Durand M; Newell KA; Kanaparthi S; Turka LA; Soulillou J-P; Houlgatte R -
Detection of Shared and Distinct Gene Expression Signatures in Tissue and Urine During Acute Rejection of Kidney Grafts
Volume: 17 Page(s): 752 - 752
04/01/2017 Authors: Keslar K; Zmijewska A; Chen J; Newell K; Heeger P; Mannon R; Fairchild R -
Integrating APOL1 Gene Variants Into Renal Transplantation: Considerations Arising From the American Society of Transplantation Expert Conference.
Am J Transplant Volume: 17 Page(s): 901 - 911
04/01/2017 Authors: Newell KA; Formica RN; Gill JS; Schold JD; Allan JS; Covington SH; Wiseman AC; Chandraker A -
Pre-Transplant Panel Reactive T Cells (PRT) with IL-15 as a Risk-Stratifier of Acute Rejection in Kidney Transplant Patients on Belatacept Therapy
Volume: 17 Page(s): 753 - 753
04/01/2017 Authors: Cravedi P; Gandolfini I; Donadei C; Fairchild R; Newell K; Mannon R; Heeger P -
A Composite Score Associated with Spontaneous Operational Tolerance in Kidney Transplant Recipients
Volume: 17 Page(s): 705 - 705
04/01/2017 Authors: Danger R; Chesneau M; Paul C; Guerif P; Durand M; Newell K; Kanaparthi S; Turka L; Soulillou J-P; Houlgatte R -
Towards Improving the Transfer of Care of Kidney Transplant Recipients.
Am J Transplant Volume: 17 Page(s): 54 - 59
01/01/2017 Authors: Gill JS; Wright AJ; Delmonico FL; Newell KA -
Transplantation tolerance: Coming of age.
Hepatology Volume: 64 Page(s): 347 - 349
08/01/2016 Authors: Adams AB; Newell KA -
Avoidance of CNI and Steroids Using Belatacept - A Preliminary Report of CTOT-16.
Volume: 16 Page(s): 401 - 402
06/01/2016 Authors: Mannon R; Stock P; Mehta A; Ikle D; Watson N; Bridges N; Robien M; Newell K -
NanoString Detection of Gene Signatures in Urine During Acute Cellular Rejection of Kidney Grafts.
Volume: 16 Page(s): 452 - 452
06/01/2016 Authors: Keslar K; Zmijewska A; Andriga J; Newell K; Mannon R; Heeger P; Fairchild R -
Late Renal Xenograft Failure Is Antibody-Mediated: Description of the Longest-Reported Survival in Pig-to-Primate Renal Xenotransplantation
Volume: 16 Page(s): 406 - 406
06/01/2016 Authors: Higginbotham L; Kim S; Mathews D; Stephenson A; Breeden C; Larsen C; Ford M; Newell K; Tector A; Adams A -
What Is the Price of Altruism?
Am J Transplant Volume: 16 Page(s): 741 - 742
03/01/2016 Authors: Formica RN; Newell KA -
Engaging Living Kidney Donors in a New Paradigm of Postdonation Care.
Am J Transplant Volume: 16 Page(s): 29 - 32
01/01/2016 Authors: Newell KA; Formica RN; Gill JS -
Interferon Gamma ELISPOT Testing as a Risk-Stratifying Biomarker for Kidney Transplant Injury: Results From the CTOT-01 Multicenter Study.
Am J Transplant Volume: 15 Page(s): 3166 - 3173
12/01/2015 Authors: Hricik DE; Augustine J; Nickerson P; Formica RN; Poggio ED; Rush D; Newell KA; Goebel J; Gibson IW; Fairchild RL -
LONG-TERM SURVIVAL OF PIG-TO-PRIMATE RENAL XENOTRANSPLANT USING COSTIMULATION-BLOCKADE IMMUNOSUPPRESSION.
Volume: 99 Page(s): S72 - S73
11/01/2015 Authors: Higginbotham L; Mathews D; Stephenson A; Breeden C; Larsen CP; Ford ML; Newell KA; Tector J; Adams AB -
Long-term survival of pig-to-primate renal xenotransplant using costimulation-blockade immunosuppression
Volume: 22 Page(s): S45 - S45
11/01/2015 Authors: Higginbotham L; Mathews D; Stephenson A; Breeden C; Larsen CP; Ford ML; Newell KA; Tector J; Adams AB -
Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients.
Am J Transplant Volume: 15 Page(s): 2908 - 2920
11/01/2015 Authors: Newell KA; Asare A; Sanz I; Wei C; Rosenberg A; Gao Z; Kanaparthi S; Asare S; Lim N; Stahly M -
Preventing T cell rejection of pig xenografts.
Int J Surg Volume: 23 Page(s): 285 - 290
11/01/2015 Authors: Higginbotham L; Ford ML; Newell KA; Adams AB -
Tolerance signatures in transplant recipients.
Curr Opin Organ Transplant Volume: 20 Page(s): 400 - 405
08/01/2015 Authors: Newell KA; Turka LA -
The Path to Greatness
AMERICAN JOURNAL OF TRANSPLANTATION Volume: 15 Page(s): 1736 - 1737
07/01/2015 Authors: Newell KA -
A common gene signature across multiple studies relate biomarkers and functional regulation in tolerance to renal allograft.
Kidney Int Volume: 87 Page(s): 984 - 995
05/01/2015 Authors: Baron D; Ramstein G; Chesneau M; Echasseriau Y; Pallier A; Paul C; Degauque N; Hernandez-Fuentes MP; Sanchez-Fueyo A; Newell KA -
Immune Phenotyping of Peripheral Blood Samples from the CTOT-10 Belatacept Study
Volume: 15
05/01/2015 Authors: Suessmuth Y; Stempora L; Johnson B; Cheeseman J; Morrison Y; Bridges N; Ikle D; Tomlanovich S; Stock P; Mannon R -
Pre-transplant antibody screening and anti-CD154 costimulation blockade promote long-term xenograft survival in a pig-to-primate kidney transplant model.
Xenotransplantation Volume: 22 Page(s): 221 - 230
01/01/2015 Authors: Higginbotham L; Mathews D; Breeden CA; Song M; Farris AB; Larsen CP; Ford ML; Lutz AJ; Tector M; Newell KA -
Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/4GalNT2 genes.
Xenotransplantation Volume: 22 Page(s): 194 - 202
01/01/2015 Authors: Estrada JL; Martens G; Li P; Adams A; Newell KA; Ford ML; Butler JR; Sidner R; Tector M; Tector J -
Rabbit ATG Induction Overcomes the Negative Influence of Pretransplant Memory T Cells On Posttransplant GFR: Results From the CTOT01 Kidney Transplant Trial.
Volume: 98 Page(s): 892 - 893
07/15/2014 Authors: Hricik D; Augustine J; Poggio E; Fairchild R; Nickerson P; Rush D; Gibson I; Formica R; Goebel J; Newell K -
Rabbit ATG Induction Overcomes the Negative Influence of Pretransplant Memory T Cells On Posttransplant GFR: Results From the CTOT01 Kidney Transplant Trial
Volume: 14 Page(s): 892 - 893
06/01/2014 Authors: Hricik D; Augustine J; Poggio E; Fairchild R; Nickerson P; Rush D; Gibson I; Formica R; Goebel J; Newell K -
Banff 2013 meeting report: inclusion of c4d-negative antibody-mediated rejection and antibody-associated arterial lesions.
Am J Transplant Volume: 14 Page(s): 272 - 283
02/01/2014 Authors: Haas M; Sis B; Racusen LC; Solez K; Glotz D; Colvin RB; Castro MCR; David DSR; David-Neto E; Bagnasco SM -
Changing Face of Immunosuppression
Volume: 14 Page(s): 58 - 59
01/01/2014 Authors: Newell KA -
Techniques for Living Donor Kidney Procurement
Page(s): 293 - 308
01/01/2014 Authors: Adams AB; Chami A; Newell KA -
Multicenter validation of urinary CXCL9 as a risk-stratifying biomarker for kidney transplant injury.
Am J Transplant Volume: 13 Page(s): 2634 - 2644
10/01/2013 Authors: Hricik DE; Nickerson P; Formica RN; Poggio ED; Rush D; Newell KA; Goebel J; Gibson IW; Fairchild RL; Riggs M -
Comparison of Baseline and Day 28 Post Transplant Renal Allograft Samples from the CTOT-10 Belatacept Study.
Volume: 13 Page(s): 225 - 225
04/01/2013 Authors: Suessmuth Y; Stempora L; Johnson B; Cheeseman J; Morrison Y; Bridges N; Ikle D; Tomlanovich S; Stock P; Mannon R -
Polyomavirus Infection Augments the CD8 T Cell Response Against Antigens Expressed by Transplanted Kidneys
Volume: 13 Page(s): 51 - 51
04/01/2013 Authors: Wang J; Dong Y; Breeden C; Albrecht J; Lukacher A; Newell K -
Multicenter Valdiation of Urinary Biomarkers in Kidney Transplantation: Urinary CXCL9 Protein Correlates with Acute Rejection and Deterioration of Kidney Function.
Volume: 13 Page(s): 98 - 98
04/01/2013 Authors: Hricik D; Nickerson P; Formica R; Poggio E; Rush D; Newell K; Goebel J; Gibson I; Fairchild R; Riggs M -
Adaptive immunity rather than viral cytopathology mediates polyomavirus-associated nephropathy in mice.
Am J Transplant Volume: 12 Page(s): 1419 - 1428
06/01/2012 Authors: Albrecht JA; Dong Y; Wang J; Breeden C; Farris AB; Lukacher AE; Newell KA -
Refinements of the Transcriptional B Cell "Signature" Associated with Clinically Tolerant Renal Transplant Recipients.
Volume: 12 Page(s): 52 - 52
05/01/2012 Authors: Newell KA; Phippard D; Asare A; Burlingham WJ; Turka LA -
Comparison of Viral Immunity in Stable Renal Allograft Recipients Treated with Belatacept or Tacrolimus
Volume: 12 Page(s): 40 - 40
05/01/2012 Authors: Suessmuth Y; Thompson PW; Breeden C; Xu H; Johnson BE; Jones RL; Stempora LA; Cheeseman J; Joseph J; Begley B -
Augmented Alloimmune Injury in a Mouse Model of Renal Transplantation Is Associated with Infection by Nephrotropic Virus
Volume: 12 Page(s): 214 - 214
05/01/2012 Authors: Dong Y; Wang J; Breeden C; Albrecht JA; Lukacher AE; Newell KA -
B cells in clinical transplantation tolerance.
Semin Immunol Volume: 24 Page(s): 92 - 95
04/01/2012 Authors: Adams AB; Newell KA -
Donor-specific indirect pathway analysis reveals a B-cell-independent signature which reflects outcomes in kidney transplant recipients.
Am J Transplant Volume: 12 Page(s): 640 - 648
03/01/2012 Authors: Haynes LD; Jankowska-Gan E; Sheka A; Keller MR; Hernandez-Fuentes MP; Lechler RI; Seyfert-Margolis V; Turka LA; Newell KA; Burlingham WJ -
Gamma interferon controls mouse polyomavirus infection in vivo.
J Virol Volume: 85 Page(s): 10126 - 10134
10/01/2011 Authors: Wilson JJ; Lin E; Pack CD; Frost EL; Hadley A; Swimm AI; Wang J; Dong Y; Breeden CP; Kalman D -
Regulatory cells and cell signatures in clinical transplantation tolerance.
Curr Opin Immunol Volume: 23 Page(s): 655 - 659
10/01/2011 Authors: Newell KA; Phippard D; Turka LA -
BIOMARKERS OF KIDNEY REJECTION IN ORGAN TRANSPLANTATION
TRANSPLANT INTERNATIONAL Volume: 24 Page(s): 160 - 160
09/01/2011 Authors: Rebollo-Mesa I; Perucha E; Sagoo P; Newell K; Turka LA; Lechler RI; Hernandez-Fuentes MP -
Miles to go.
Am J Transplant Volume: 11 Page(s): 1119 - 1120
06/01/2011 Authors: Kirk AD; Knechtle SJ; Larsen CP; Newell KA; Pearson TC -
Alloimmunity Exacerbates Polyomavirus Associated Nephropathy (PVAN)
Volume: 11 Page(s): 42 - 42
04/01/2011 Authors: Dong Y; Wang J; Breeden C; Albrecht JA; Lukacher AE; Newell KA -
The Role of PD-1 in Spontaneous Kidney Allograft Tolerance
Volume: 11 Page(s): 187 - 187
04/01/2011 Authors: Albrecht JA; Wang J; Dong Y; Breeden C; Hadley A; Mlaver D; Lukacher AE; Newell KA -
Making a B-line for transplantation tolerance.
Am J Transplant Volume: 11 Page(s): 420 - 421
03/01/2011 Authors: Newell KA; Chong AS -
Clinical transplantation tolerance.
Semin Immunopathol Volume: 33 Page(s): 91 - 104
03/01/2011 Authors: Newell KA -
Paired kidney donation: a (virtual) balancing act.
Am J Transplant Volume: 11 Page(s): 194 - 195
02/01/2011 Authors: Bingaman AW; Bray RA; Gebel HM; Newell KA -
Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans.
J Clin Invest Volume: 120 Page(s): 1848 - 1861
06/01/2010 Authors: Sagoo P; Perucha E; Sawitzki B; Tomiuk S; Stephens DA; Miqueu P; Chapman S; Craciun L; Sergeant R; Brouard S -
Identification of a B cell signature associated with renal transplant tolerance in humans.
J Clin Invest Volume: 120 Page(s): 1836 - 1847
06/01/2010 Authors: Newell KA; Asare A; Kirk AD; Gisler TD; Bourcier K; Suthanthiran M; Burlingham WJ; Marks WH; Sanz I; Lechler RI -
Donor Specific Regulation and B Cell Tolerance Signature in Renal Transplant Recipients.
Volume: 10 Page(s): 487 - 487
04/01/2010 Authors: Haynes LD; Jankowska-Gan E; Seyfert-Margolis VL; Newell KA; Turka LA; Asare A; Bourcier KD; Burlingham WJ -
Influence of Timing and Origin of Infection on Polyoma Virus Nephropathy (PVN)
Volume: 10 Page(s): 160 - 160
04/01/2010 Authors: Dong Y; Wang J; Breeden C; Lukacher AE; Newell KA -
Dynamic T cell migration program provides resident memory within intestinal epithelium.
J Exp Med Volume: 207 Page(s): 553 - 564
03/15/2010 Authors: Masopust D; Choo D; Vezys V; Wherry EJ; Duraiswamy J; Akondy R; Wang J; Casey KA; Barber DL; Kawamura KS -
What Is Optimal Induction Therapy for Expanded Criteria Donor Kidneys?
Volume: 10 Page(s): 31 - 31
01/01/2010 Authors: Tso PL; Turgeon NA; Newell KA; Pearson TC; Larsen CP; Kirk AD -
Early Results from the Clinical Trials in Organ Transplantation (CTOT-01) Trial Identify Noninvasive Markers as Correlates of 6-Month Renal Allograft Pathology.
Volume: 9 Page(s): 191 - 191
01/01/2009 Authors: Hricik D; Poggio E; Newell K; Rush D; Nickerson P; Formica R; Akalin E; Goebel J; Fairchild R; Gebel H -
Dynamic Hypercoagulability Following Pancreas Transplantation.
Volume: 9 Page(s): 616 - 617
01/01/2009 Authors: Shen L; Agarwal A; Turgeon N; Tso P; Newell K; Pearson T; Larsen C; Winkler A; Duncan A; Kirk A -
Effects of MHC Matching on Polyoma Virus Nephropathy (PVN).
Volume: 9 Page(s): 378 - 378
01/01/2009 Authors: Dong Y; Lin E; Wang J; Breeden C; Larsen CP; Lukacher AE; Newell KA -
A Single Center Comparison between Basiliximab and Rabbit Anti-Thymocyte Globulin Induction Therapy for Simultaneous Pancreas and Kidney Transplantation.
Volume: 9 Page(s): 547 - 547
01/01/2009 Authors: Shen L; Turgeon N; Tso P; Newell K; Pearson T; Larsen C; Kirk A -
Impact of Rabbit Anti-Thymocyte Globulin Induction Therapy on Reactivation of BK Virus in Renal Transplant Recipients.
Volume: 9 Page(s): 422 - 422
01/01/2009 Authors: Agarwal A; Metha A; Kokko K; Turgeon NA; Tso PY; Newell KA; Larsen CP; Kirk AD -
Peripheral B Cell Markers Identify Tolerant Renal Transplant Recipients.
Volume: 9 Page(s): 723 - 723
01/01/2009 Authors: Newell KA; Asare A; Kirk AD; Gisler T; Suthanthiran M; Burlingham WJ; Bourcier K; Marks WH; Turka LA; Seyfert-Margolis V -
The role of positive costimulatory molecules in transplantation and tolerance.
Curr Opin Organ Transplant Volume: 13 Page(s): 366 - 372
08/01/2008 Authors: Agarwal A; Newell KA -
Finding the right job for the tool: alemtuzumab and its role in renal transplantation.
Am J Transplant Volume: 8 Page(s): 1363 - 1364
07/01/2008 Authors: Newell KA; Cendales LC; Kirk AD -
Laparoscopic donor nephrectomy: Multiple arteries are not a predictor of recipient outcomes.
Volume: 8 Page(s): 457 - 457
05/01/2008 Authors: Bearden CM; Tso PL; Turgeon NA; Ogan K; Pearson TC; Kirk AD; Larsen CP; Newell KA -
Impact of rabbit anti-thymocyte globulin induction therapy on reactivation of BK virus in renal transplant recipients.
Volume: 8 Page(s): 460 - 460
05/01/2008 Authors: Agarwal A; Meetha A; Kokko KE; Turgeon NA; Tso PL; Newell KA; Pearson TC; Larsen CP; Kirk AD -
A unique B cell signature associated with operational tolerance
Volume: 8 Page(s): 316 - 316
05/01/2008 Authors: Newell KA; Asare A; Kirk AD; Gisler T; Suthanthiran M; Burlingham W; Marks W; Turka L; Seyfert-Margolis V -
B cells and alloantibody are not sufficient to mediate rejection of intestinal allografts in mice
Volume: 8 Page(s): 487 - 487
05/01/2008 Authors: Dong Y; Wang J; Sun J; Williams IR; Newell KA -
TGF beta and long term acceptance of intestinal allografts by Aly/Aly mice
Volume: 8 Page(s): 403 - 404
05/01/2008 Authors: Wang J; Doug Y; Sun J; Willams IR; Newell KA -
PD-1 negatively regulates CD8 T cell-mediated mucosal autoimmunity
FASEB JOURNAL Volume: 22
04/01/2008 Authors: Vezys V; Masopust D; Sharpe A; Freeman G; Newell K; Ahmed R -
Immune responsiveness and protective immunity after transplantation.
Transpl Int Volume: 21 Page(s): 293 - 303
04/01/2008 Authors: Gangappa S; Kokko KE; Carlson LM; Gourley T; Newell KA; Pearson TC; Ahmed R; Larsen CP -
Transplantation tolerance.
Semin Nephrol Volume: 27 Page(s): 487 - 497
07/01/2007 Authors: Newell KA; Larsen CP -
Indefinite survival of intestinal allografts in NIK mutant mice.
Volume: 7 Page(s): 222 - 223
05/01/2007 Authors: Wang J; Dong Y; Sun J; Taylor R; Williams IR; Newell KA -
Influence of HLA-C locus antigens in BK viremia
Volume: 68 Page(s): S15 - S15
01/01/2007 Authors: Mendel B; Newell K; Kokko K; Bray R; Gebel H -
Donor lymphoid organs are a major site of alloreactive T-cell priming following intestinal transplantation.
Am J Transplant Volume: 6 Page(s): 2563 - 2571
11/01/2006 Authors: Wang J; Dong Y; Sun J-Z; Taylor RT; Guo C; Alegre M-L; Williams IR; Newell KA -
How can we measure immunologic tolerance in humans?
J Am Soc Nephrol Volume: 17 Page(s): 2652 - 2663
10/01/2006 Authors: Najafian N; Albin MJ; Newell KA -
Transplanting the highly sensitized patient: The emory algorithm.
Am J Transplant Volume: 6 Page(s): 2307 - 2315
10/01/2006 Authors: Bray RA; Nolen JDL; Larsen C; Pearson T; Newell KA; Kokko K; Guasch A; Tso P; Mendel JB; Gebel HM -
Toward transplantation tolerance: a large step on a long road.
Am J Transplant Volume: 6 Page(s): 1989 - 1990
09/01/2006 Authors: Newell KA; Larsen CP -
CMV-IVIG for prevention of Epstein Barr virus disease and posttransplant lymphoproliferative disease in pediatric liver transplant recipients.
Volume: 6 Page(s): 1906 - 1912
08/01/2006 Authors: Green M; Michaels MG; Katz BZ; Burroughs M; Gerber D; Shneider BL; Newell K; Rowe D; Reyes J -
Tolerance assays: measuring the unknown.
Transplantation Volume: 81 Page(s): 1503 - 1509
06/15/2006 Authors: Newell KA; Larsen CP -
A mouse model for polyomavirus-associated nephropathy of kidney transplants.
Am J Transplant Volume: 6 Page(s): 913 - 922
05/01/2006 Authors: Han Lee ED; Kemball CC; Wang J; Dong Y; Stapler DC; Hamby KM; Gangappa S; Newell KA; Pearson TC; Lukacher AE -
Therapeutic applications of costimulation blockade in transplantation
Volume: 231
03/26/2006 Authors: Newell KA -
Immunosuppressive and trafficking properties of donor splenic and bone marrow dendritic cells.
Transplantation Volume: 81 Page(s): 455 - 462
02/15/2006 Authors: Emmanouilidis N; Guo Z; Dong Y; Newton-West M; Adams AB; Lee EDH; Wang J; Pearson TC; Larsen CP; Newell KA -
Transplant tolerance: converging on a moving target.
Transplantation Volume: 81 Page(s): 1 - 6
01/15/2006 Authors: Newell KA; Larsen CP; Kirk AD -
Multidetector-row CT angiography for preoperative evaluation of potential laparoscopic renal donors: how accurate are we?
Clin Imaging Volume: 30 Page(s): 120 - 126
01/01/2006 Authors: Namasivayam S; Small WC; Kalra MK; Torres WE; Newell KA; Mittal PK -
Immunogenicity of intestinal allografts: Contributions of the intestinal microenvironment.
Volume: 5 Page(s): 481 - 481
05/01/2005 Authors: Wang J; Dong Y; Taylor R; Williams IR; Newell KA -
Pre-emptive renal transplantation: Does everyone benefit?
Volume: 5 Page(s): 261 - 262
05/01/2005 Authors: Newell KA; Wijkstrom M; Guidinger MK; Sung RS -
Comparable graft survival in sensitized and unsensitized renal transplant recipients: A 5 year single center review.
Volume: 5 Page(s): 456 - 456
05/01/2005 Authors: Nolen JDL; Gebel HM; Larsen C; Pearson T; Newell K; Kokko K; Guasch A; Tso P; Bray RA -
Single center experience with allograft pancreatectomy.
Volume: 5 Page(s): 358 - 358
05/01/2005 Authors: Tso PL; Newell KA; Pearson TC; Larsen CP -
The role of enteric flora-stimulated TLR signaling in the maturation of isolated lymphoid follicles in the small intestine
Volume: 19 Page(s): A779 - A779
03/04/2005 Authors: Taylor RT; Sherman M; Newell KA; Williams IR -
A mouse model for polyomavirus-associated nephropathy of kidney transplants
JOURNAL OF NEUROVIROLOGY Volume: 14 Page(s): 41 - 41
01/01/2005 Authors: Lee EDH; Kemball CC; Wang J; Dong Y; Stapler DC; Hamby KM; Gangappa S; Newell KA; Pearson TC; Lukacher AE -
A 5 year single center review of graft survival in sensitized renal transplant recipients
Volume: 66 Page(s): S56 - S56
01/01/2005 Authors: Nolen JDL; Bray RA; Pearson T; Larsen C; Newell K; Kokko K; Guasch A; Tso P; Gebel HM -
Intestinal cryptopatch formation in mice requires lymphotoxin alpha and the lymphotoxin beta receptor.
J Immunol Volume: 173 Page(s): 7183 - 7189
12/15/2004 Authors: Taylor RT; Lgering A; Newell KA; Williams IR -
Lymphotoxin signaling is necessary for intestinal cryptopatch development
Volume: 18 Page(s): A463 - A463
03/23/2004 Authors: Taylor RT; Luegering A; Newell KA; Williams IR -
Impaired rejection in the absence of light: A comparison of CD8 and CD4 T cells
Volume: 4 Page(s): 413 - 413
01/01/2004 Authors: Guo Z; Dong Y; Wang J; Newton-West M; Fu YX; Newell KA -
Secondary lymphoid organs and the immune response to intestinal allografts.
Volume: 4 Page(s): 247 - 247
01/01/2004 Authors: Wang J; Dong Y; Guo Z; Newton-West M; Alegre M; Newell KA -
Inability to clear polyoma virus in MHC disparate murine kidney transplant model results in accelerated graft rejection.
Volume: 4 Page(s): 599 - 599
01/01/2004 Authors: Lee EDH; Wang J; Dong Y; Lukacher AE; Newell KA; Pearson TC; Larsen CP -
Simultaneous pancreas-kidney transplantation utilizing a common arterial conduit: early experience and potential applications.
Am J Transplant Volume: 3 Page(s): 1440 - 1443
11/01/2003 Authors: Tso PL; Cash MP; Pearson TC; Larsen CP; Newell KA -
Long-term survival of intestinal allografts induced by costimulation blockade, busulfan and donor bone marrow infusion.
Am J Transplant Volume: 3 Page(s): 1091 - 1098
09/01/2003 Authors: Guo Z; Wang J; Dong Y; Adams AB; Shirasugi N; Kim O; Hart J; Newton-West M; Pearson TC; Larsen CP -
Conventional immunosuppression is compatible with costimulation blockade-based, mixed chimerism tolerance induction.
Am J Transplant Volume: 3 Page(s): 895 - 901
07/01/2003 Authors: Adams AB; Shirasugi N; Jones TR; Williams MA; Durham MM; Ha J; Dong Y; Guo Z; Newell KA; Pearson TC -
Role of 4-1BB in allograft rejection mediated by CD8+ T cells.
Am J Transplant Volume: 3 Page(s): 543 - 551
05/01/2003 Authors: Wang J; Guo Z; Dong Y; Kim O; Hart J; Adams A; Larsen CP; Mittler RS; Newell KA -
Secondary lymphoid organs are important but not absolutely required for allograft responses.
Am J Transplant Volume: 3 Page(s): 259 - 266
03/01/2003 Authors: Zhou P; Hwang KW; Palucki D; Kim O; Newell KA; Fu Y-X; Alegre M-L -
Impaired NF-kappaB activation in T cells permits tolerance to primary heart allografts and to secondary donor skin grafts.
Am J Transplant Volume: 3 Page(s): 139 - 147
02/01/2003 Authors: Zhou P; Hwang KW; Palucki DA; Guo Z; Boothby M; Newell KA; Alegre M-L -
A critical role for 4-1BB in allograft rejection mediated by CD8(+) T cells
Volume: 83 Page(s): 124A - 124A
01/01/2003 Authors: Kim OS; Guo Z; Wang J; Hart J; Larsen CP; Newell KA -
Transplantation of the intestine: is it truly different?
Am J Transplant Volume: 3 Page(s): 1 - 2
01/01/2003 Authors: Newell KA -
Critical role for 4-1BB in-allograft rejection mediated by CD8(+) T cells
Volume: 16 Page(s): 124A - 124A
01/01/2003 Authors: Kim OS; Guo Z; Wang J; Hart J; Larsen CP; Newell KA -
Hand-assisted laparoscopic living-donor nephrectomy as an alternative to traditional laparoscopic living-donor nephrectomy.
Am J Transplant Volume: 2 Page(s): 983 - 988
11/01/2002 Authors: Buell JF; Hanaway MJ; Potter SR; Cronin DC; Yoshida A; Munda R; Alexander JW; Newell KA; Bruce DS; Woodle ES -
Signaling via LTbetaR on the lamina propria stromal cells of the gut is required for IgA production.
Nat Immunol Volume: 3 Page(s): 576 - 582
06/01/2002 Authors: Kang H-S; Chin RK; Wang Y; Yu P; Wang J; Newell KA; Fu Y-X -
Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney.
J Immunol Volume: 168 Page(s): 5817 - 5823
06/01/2002 Authors: Cunningham PN; Dyanov HM; Park P; Wang J; Newell KA; Quigg RJ -
Membrane lymphotoxin regulates CD8(+) T cell-mediated intestinal allograft rejection
LABORATORY INVESTIGATION Volume: 82 Page(s): 133A - 133A
01/01/2002 Authors: Kim OS; Guo Z; Wang J; Wu Q; Hart J; Fu YX; Newell KA -
The role of TNF receptor and TNF superfamily molecules in organ transplantation.
Am J Transplant Volume: 2 Page(s): 12 - 18
01/01/2002 Authors: Adams AB; Larsen CP; Pearson TC; Newell KA -
Membrane lymphotoxin regulates CD8(+) T cell-mediated intestinal allograft rejection
MODERN PATHOLOGY Volume: 15 Page(s): 133A - 133A
01/01/2002 Authors: Kim OS; Guo Z; Wang J; Wu Q; Hart J; Fu YX; Newell KA -
Cutting edge: membrane lymphotoxin regulates CD8(+) T cell-mediated intestinal allograft rejection.
J Immunol Volume: 167 Page(s): 4796 - 4800
11/01/2001 Authors: Guo Z; Wang J; Meng L; Wu Q; Kim O; Hart J; He G; Zhou P; Thistlethwaite JR; Alegre ML -
Epidemiology and clinical consequences of vancomycin-resistant enterococci in liver transplant patients.
Transplantation Volume: 72 Page(s): 1032 - 1037
09/27/2001 Authors: Bakir M; Bova JL; Newell KA; Millis JM; Buell JF; Arnow PM -
CD8 T cell-mediated rejection of intestinal allografts is resistant to inhibition of the CD40/CD154 costimulatory pathway.
Transplantation Volume: 71 Page(s): 1351 - 1354
05/15/2001 Authors: Guo Z; Meng L; Kim O; Wang J; Hart J; He G; Alegre ML; Thistlethwaite JR; Pearson TC; Larsen CP -
Are concerns over right laparoscopic donor nephrectomy unwarranted?
Ann Surg Volume: 233 Page(s): 645 - 651
05/01/2001 Authors: Buell JF; Edye M; Johnson M; Li C; Koffron A; Cho E; Kuo P; Johnson L; Hanaway M; Potter SR -
Different mechanisms of cardiac allograft rejection in wildtype and CD28-deficient mice.
Am J Transplant Volume: 1 Page(s): 38 - 46
05/01/2001 Authors: Szot GL; Zhou P; Rulifson I; Wang J; Guo Z; Kim O; Newel KA; Thistlethwaite JR; Bluestone JA; Alegre ML -
T cell subsets and CD28 signals in cardiac allograft rejection
FASEB JOURNAL Volume: 15 Page(s): A350 - A350
03/07/2001 Authors: Alegre ML; Szot G; Zhou P; Rulifson I; Wang J; Guo Z; Kim O; Newell K; Thistlethwaite JR; Bluestone J -
Transplantation and the CD28/CTLA4/B7 pathway.
Transplant Proc Volume: 33 Page(s): 209 - 211
01/01/2001 Authors: Alegre M; Fallarino F; Zhou P; Frauwirth K; Thistlethwaite J; Newell K; Gajewski T; Bluestone J -
Role of STAT6 signaling in the induction and long-term maintenance of tolerance mediated by CTLA4-Ig.
Transplant Proc Volume: 33 Page(s): 214 - 216
01/01/2001 Authors: Zhou P; Szot G; Guo Z; Kim O; He G; Wang J; Grusby M; Newell K; Thistlethwaite J; Bluestone J -
Blockade of the CD40 pathway fails to prevent CD8 T cell-mediated intestinal allograft rejection.
Transplant Proc Volume: 33 Page(s): 418 - 420
01/01/2001 Authors: Meng L; Guo Z; Kim O; He G; Hart J; Szot GL; Wang J; Pearson TC; Larsen CP; Newell KA -
Hand-assisted laparoscopic live-donor nephrectomy.
J Am Coll Surg Volume: 192 Page(s): 132 - 136
01/01/2001 Authors: Buell JF; Alverdy J; Newell KA; Yoshida A; Limsrichamrern S; Woodle ES; Bruce DS -
Unsuspected acquired coagulation factor deficiencies as a result of orthotopic liver transplantation.
Volume: 96 Page(s): 81B - 81B
11/16/2000 Authors: Baron JM; Samuels B; Miller JB; Newell KA; Baron BW -
Role of STAT4 and STAT6 signaling in allograft rejection and CTLA4-Ig-mediated tolerance.
J Immunol Volume: 165 Page(s): 5580 - 5587
11/15/2000 Authors: Zhou P; Szot GL; Guo Z; Kim O; He G; Wang J; Grusby MJ; Newell KA; Thistlethwaite JR; Bluestone JA -
Risk factors and surveillance for surgical wound infections
SURGERY Volume: 128 Page(s): S2 - S13
10/01/2000 Authors: Martone WJ; Nichols WJ; Christou NV; Barie PS; Wilson SE; Condon RE; Lee JT; Linden PK; Malangoni MA; Newell K -
Diagnosis and treatment of uncomplicated and complicated surgical infections
SURGERY Volume: 128 Page(s): S19 - S30
10/01/2000 Authors: Nichols RL; Martone WJ; Wilson SE; Chambers HF; Fry DE; Dunn DL; Gorbach SL; Condon RE; Newell K; Dellinger EP -
Combined liver and kidney transplantation in children.
Transplantation Volume: 70 Page(s): 100 - 105
07/15/2000 Authors: Grewal HP; Brady L; Cronin DC; Loss GE; Siegel CT; Oswald K; Fisher JS; Bruce DS; Aronson AJ; Woodle ES -
Primary living-donor liver transplantation at the University of Chicago: technical aspects of the first 104 recipients.
Ann Surg Volume: 232 Page(s): 104 - 111
07/01/2000 Authors: Millis JM; Cronin DC; Brady LM; Newell KA; Woodle ES; Bruce DS; Thistlethwaite JR; Broelsch CE -
Different effects of various strategies for blocking CD28/B7 interactions on intestinal allograft rejection.
TRANSPLANTATION Volume: 69 Page(s): S416 - S417
04/27/2000 Authors: Guo Z; Meng LZ; Kim O; He G; Szot GL; Hart J; Wang J; Collins M; Thistlethwaite JR; Sharpe AH -
Blockade of the CD40 costimulatory pathway fails to prevent CD8 T cell-mediated rejection of intestinal allografts.
TRANSPLANTATION Volume: 69 Page(s): S416 - S416
04/27/2000 Authors: Meng LZ; Guo Z; Kim O; He G; Hart J; Szot GL; Wang J; Larsen CP; Newell KA -
Early corticosteroid cessation at one week following kidney transplant under tacrolimus and Mycophenolate Mofetil (MMF) immunosuppresion, three-year follow-up.
TRANSPLANTATION Volume: 69 Page(s): S134 - S134
04/27/2000 Authors: Buell JF; Kulkarni S; Grewal HP; Kopelan A; Yoshida A; Swanson A; Cronin DC; Bruce DS; Newell KA; Thistlethwaite JR -
Signaling through STAT4 or STAT6 is not required for acute allograft rejection or for the induction of tolerance by CTLA4-Ig treatment in a murine cardiac transplant model.
TRANSPLANTATION Volume: 69 Page(s): S379 - S379
04/27/2000 Authors: Zhou P; Szot GL; Guo Z; He G; Wang J; Newell KA; Thistlethwaite JR; Bluestone JA; Alegre ML -
Role of CD8+T cells in cardiac allograft rejection in wild-type and CD28-deficient mice.
TRANSPLANTATION Volume: 69 Page(s): S413 - S413
04/27/2000 Authors: Szot GL; Zhou P; Wang J; Guo Z; Newell KA; Thistlethwaite JR; Bluestone JA; Alegre ML -
Comparison of blocking CD28 and CD40 pathways on intestinal allograft rejection
FASEB JOURNAL Volume: 14 Page(s): A1070 - A1070
04/20/2000 Authors: Guo Z; Meng L; Kim O; He G; Szot GL; Wang J; Hart J; Thistlethwaite JR; Newell KA -
Absence of host B7 expression is sufficient for long-term murine vascularized heart allograft survival.
Transplantation Volume: 69 Page(s): 904 - 909
03/15/2000 Authors: Szot GL; Zhou P; Sharpe AH; He G; Kim O; Newell KA; Bluestone JA; Thistlethwaite JR -
Cutting edge: blockade of the CD28/B7 costimulatory pathway inhibits intestinal allograft rejection mediated by CD4+ but not CD8+ T cells.
J Immunol Volume: 163 Page(s): 2358 - 2362
09/01/1999 Authors: Newell KA; He G; Guo Z; Kim O; Szot GL; Rulifson I; Zhou P; Hart J; Thistlethwaite JR; Bluestone JA -
Murine allogenic heart graft rejection is dependant on indirect B7 mediated costimulation
TRANSPLANTATION Volume: 67 Page(s): S590 - S590
05/15/1999 Authors: Zhou P; Szot GL; Sharpe MSA; He G; Kim OS; Newell KA; Bluestone JA; Thistlethwaite JR -
Early corticosteroid withdrawal with tacrolimus and mycophenolate mofetil (MMF) immuno-suppression in renal transplantation: Eighteen-month follow-up
TRANSPLANTATION Volume: 67 Page(s): S545 - S545
05/15/1999 Authors: Buell JF; Grewal HP; Kristo B; Kopelan A; Kulkarni S; Yoshida A; Kim E; Siegel C; Cronin DC; Bruce DS -
Anti-CD8 monoclonal antibody-mediated inhibition of intestinal allograft rejection is associated with downregulation of TH1-type cytokines
TRANSPLANTATION Volume: 67 Page(s): S603 - S603
05/15/1999 Authors: Guo Z; He G; Kim OS; Hart J; Thistlethwaite JR; Newell KA -
African-American patients with renal failure secondary to diabetes should be referred for combined kidney-pancreas transplant
TRANSPLANTATION Volume: 67 Page(s): S567 - S567
05/15/1999 Authors: Buell J; Thistlethwaite JR; Kristo B; Yoshida A; Siegel C; Kim E; Newell K; Cronin D; Millis JM; Woodle ES -
Incidence and outcome of vancomycin-resistant enterococcus infection in pediatric liver transplant patients.
TRANSPLANTATION Volume: 67 Page(s): S232 - S232
04/15/1999 Authors: Cronin DC; Brady L; Mead JM; Siegel C; Yoshida A; Oswald K; Newell KA; Millis JM -
Comparison of daclizumab vs. ATGAM induction in kidney pancreas transplantation
TRANSPLANTATION Volume: 67 Page(s): S223 - S223
04/15/1999 Authors: Siegal C; Mead J; Buell J; Yoshida A; Newell K; Woodle ES; Thistlethwaite JR; Bruce D -
CTLA4Ig fails to prevent intestinal allograft rejection due to an inability to inhibit CD8 T cell responses
TRANSPLANTATION Volume: 67 Page(s): S45 - S45
04/15/1999 Authors: Newell KA; He G; Guo Z; Kim O; Hart J; Collins M; Thistlewaite JR; Bluestone JA -
The role of CD8 and CD4 T cells in intestinal allograft rejection: a comparison of monoclonal antibody-treated and knockout mice.
Transplantation Volume: 67 Page(s): 131 - 137
01/15/1999 Authors: He G; Hart J; Kim OS; Szot GL; Siegel CT; Thistlethwaite JR; Newell KA -
Differential effect of an anti-CD8 monoclonal antibody on rejection of murine intestine and cardiac allografts.
Transplant Proc Volume: 31 Page(s): 1239 - 1241
01/01/1999 Authors: He G; Kim OS; Thistlethwaite JR; Hart J; Siegel CT; Szot GL; Newell KA -
Modified surgical model of paratopic small bowel transplantation in mice.
J Surg Res Volume: 80 Page(s): 188 - 193
12/01/1998 Authors: He G; Hart J; Thistlethwaite JR; Newell KA -
Elimination of hepatic artery thrombosis in living donor liver. Transplantation with microvascular reconstruction
HEPATOLOGY Volume: 28 Page(s): 264A - 264A
10/01/1998 Authors: Millis JM; Cronin DC; Newell KA; Bruce DS; Woodle ES; Siegel C; Brady L; Thistlethwaite JR -
Role of CD8+ and CD4+ T cells in the rejection of murine intestinal allografts.
Transplant Proc Volume: 30 Page(s): 2592 - 2593
09/01/1998 Authors: He G; Hart J; Thistlethwaite JR; Newell KA -
Complications in 100 living-liver donors.
Ann Surg Volume: 228 Page(s): 214 - 219
08/01/1998 Authors: Grewal HP; Thistlewaite JR; Loss GE; Fisher JS; Cronin DC; Siegel CT; Newell KA; Bruce DS; Woodle ES; Brady L -
Imaging of pancreatic transplantation using portal venous and enteric exocrine drainage.
AJR Am J Roentgenol Volume: 171 Page(s): 157 - 163
07/01/1998 Authors: Dachman AH; Newmark GM; Thistlethwaite JR; Oto A; Bruce DS; Newell KA -
Pathogenesis of early operative site infections after orthotopic liver transplantation.
Transplantation Volume: 65 Page(s): 1500 - 1503
06/15/1998 Authors: Arnow PM; Zachary KC; Thistlethwaite JR; Thompson KD; Bova JL; Newell KA -
Tacrolimus/mycophenolate provides superior immunosuppression relative to neoral/mycophenolate in synchronous pancreas-kidney transplantation.
Transplant Proc Volume: 30 Page(s): 1538 - 1540
06/01/1998 Authors: Bruce DS; Woodle ES; Newell KA; Millis JM; Cronin DC; Loss GE; Grewal HP; Siegel CT; Pellar S; Josephson MA -
Cyclosporine versus cyclosporine microemulsion in pediatric liver transplant recipients.
Transplant Proc Volume: 30 Page(s): 1435 - 1436
06/01/1998 Authors: Loss GE; Brady L; Grewal HP; Siegel CT; Mead J; Bruce DS; Cronin DC; Woodle ES; Newell KA; Thistlethwaite JR -
Tacrolimus therapy for refractory acute renal allograft rejection: a 4-year experience with an aggressive approach.
Transplant Proc Volume: 30 Page(s): 1234 - 1235
06/01/1998 Authors: Turner CD; Bruce DS; Cronin DC; Loss GE; Grewal H; Siegel C; Millis JM; Newell KA; Davis B; Todo T -
Successful use of tacrolimus for initial rejection episodes after liver transplantation.
Transplant Proc Volume: 30 Page(s): 1407 - 1408
06/01/1998 Authors: Millis JM; Cronin DC; Newell KA; Bruce DS; Woodle ES; Grewal HP; Loss GE; Lissoos T; Conjeevaram H; Schiano T -
Inhibition of intestinal allograft rejection by an anti-CD8 monoclonal antibody is not mediated by depletion alone.
Transplant Proc Volume: 30 Page(s): 1069 - 1070
06/01/1998 Authors: He G; Hart J; Thistlethwaite JR; Newell KA -
Reversal of delayed hyperacute renal allograft rejection with a tacrolimus-based therapeutic regimen.
Transplant Proc Volume: 30 Page(s): 1249 - 1250
06/01/1998 Authors: Loss GE; Grewal HP; Siegel CT; Peace D; Mead J; Bruce DS; Cronin DC; Millis JM; Newell KA; Woodle ES -
Corticosteroid cessation 1 week following renal transplantation using tacrolimus/mycophenolate mofetil based immunosuppression.
Transplant Proc Volume: 30 Page(s): 1378 - 1379
06/01/1998 Authors: Grewal HP; Thistlethwaite JR; Loss GE; Bruce DS; Siegel CT; Cronin DC; Newell KA; Millis JM; Woodle ES -
An analysis of hepatic retransplantation in children.
Transplantation Volume: 65 Page(s): 1172 - 1178
05/15/1998 Authors: Newell KA; Millis JM; Bruce DS; Woodle ES; Cronin DC; Loss G; Grewal H; Alonso EM; Dillon JJ; Whitington PF -
Effects of tacrolimus, mycophenolate mofetil, and cyclosporine microemulsion on rejection incidence in synchronous pancreas-kidney transplantation.
Transplant Proc Volume: 30 Page(s): 507 - 508
03/01/1998 Authors: Bruce DS; Woodle ES; Newell KA; Millis JM; Cronin DC; Loss GE; Pellar S; Josephson MA; Thistlethwaite JR -
Synchronous pancreas-kidney transplantation with portal venous and enteric exocrine drainage: outcome in 70 consecutive cases.
Transplant Proc Volume: 30 Page(s): 270 - 271
03/01/1998 Authors: Bruce DS; Newell KA; Woodle ES; Cronin DC; Grewal HP; Millis JM; Ruebe M; Josephson MA; Thistlethwaite JR -
Incidence and outcome of infection by vancomycin-resistant Enterococcus following orthotopic liver transplantation.
Transplantation Volume: 65 Page(s): 439 - 442
02/15/1998 Authors: Newell KA; Millis JM; Arnow PM; Bruce DS; Woodle ES; Cronin DC; Loss GE; Grewal H; Lissoos T; Schiano T -
Clinical course and management of inflammatory bowel disease after liver transplantation.
Transplantation Volume: 65 Page(s): 393 - 396
02/15/1998 Authors: Befeler AS; Lissoos TW; Schiano TD; Conjeevaram H; Dasgupta KA; Millis JM; Newell KA; Thistlethwaite JR; Baker AL -
Morphologic bone marrow changes in patients with posttransplantation lymphoproliferative disorders.
Am J Surg Pathol Volume: 22 Page(s): 208 - 214
02/01/1998 Authors: Koeppen H; Newell K; Baunoch DA; Vardiman JW -
Treatment with either anti-CD4 or anti-CD8 monoclonal antibodies blocks alphabeta T cell-mediated rejection of intestinal allografts in mice.
Transplantation Volume: 64 Page(s): 959 - 965
10/15/1997 Authors: Newell KA; He G; Hart J; Thistlethwaite JR -
Successful combined heart-liver transplantation in adults
HEPATOLOGY Volume: 26 Page(s): 1406 - 1406
10/01/1997 Authors: Befeler AS; Schiano TD; Lissoos TW; Conjeevaram H; Millis JM; Newell KA; Thistlethwaite JR; Albertucci M; Baker AL -
Reversal of accelerated renal allograft rejection with FK 506.
Clin Transplant Volume: 11 Page(s): 251 - 254
08/01/1997 Authors: Woodle ES; Newell KA; Haas M; Bartosh S; Josephson MA; Millis JM; Bruce DS; Piper JB; Aronson AJ; Thistlethwaite JR -
Association between liver transplantation for Langerhans cell histiocytosis, rejection, and development of posttransplant lymphoproliferative disease in children.
J Pediatr Volume: 131 Page(s): 98 - 104
07/01/1997 Authors: Newell KA; Alonso EM; Kelly SM; Rubin CM; Thistlethwaite JR; Whitington PF -
Studies of intestinal allograft rejection using a murine paratopic model.
GASTROENTEROLOGY Volume: 112 Page(s): A1462 - A1462
04/01/1997 Authors: Newell KA; He G; Hart J; Thistlewaite JR -
Tacrolimus treatment of steroid-resistant rejection provides economic advantages compared with OKT3 therapy.
Transplant Proc Volume: 29 Page(s): 1549
01/01/1997 Authors: Millis JM; Cronin DC; Newell KA; Piper JB; Woodle ES; Bruce DS; Conjeevaram H; Baker AL; Thistlethwaite JR -
Impact of a liberalized donor acceptance policy on liver transplantation.
Transplant Proc Volume: 29 Page(s): 484
01/01/1997 Authors: Millis JM; Cronin DC; Piper JB; Newell KA; Bruce DS; Woodle ES; Davis B; Seaman E; Thistlethwaite JR -
Retransplantation for failed hepatic allografts in children.
Transplant Proc Volume: 29 Page(s): 442 - 443
01/01/1997 Authors: Newell KA; Alonso EM; Millis JM; Piper JB; Bruce DS; Woodle ES; Cronin DC; Whitington PF; Thistlethwaite JR -
Biliary complications in living donor liver transplantation.
Transplant Proc Volume: 29 Page(s): 419 - 420
01/01/1997 Authors: Cronin DC; Alonso EM; Piper JB; Newell KA; Bruce DS; Woodle ES; Whitington PF; Thistlethwaite JR; Millis JM -
Tacrolimus therapy for refractory renal allograft rejection: experience with steroid withdrawal.
Transplant Proc Volume: 29 Page(s): 307
01/01/1997 Authors: Cronin DC; Bruce DS; Newell KA; Josephson MA; Millis JM; Piper JB; Ruebe M; Kirby M; Thistlethwaite JR; Woodle ES -
Comparison of pancreas transplantation with portal venous and enteric exocrine drainage to the standard technique utilizing bladder drainage of exocrine secretions.
Transplantation Volume: 62 Page(s): 1353 - 1356
11/15/1996 Authors: Newell KA; Bruce DS; Cronin DC; Woodle ES; Millis JM; Piper JB; Huss E; Thistlethwaite JR -
Use of polytetrafluoroethylene patch for temporary wound closure after pediatric liver transplantation.
Transplantation Volume: 62 Page(s): 1034 - 1036
10/15/1996 Authors: Seaman DS; Newell KA; Piper JB; Bruce DS; Woodle ES; Cronin DC; Alonso EM; Whitington PF; Thistlethwaite JR; Millis JM -
Tacrolimus therapy for refractory acute renal allograft rejection: definition of the histologic response by protocol biopsies.
Transplantation Volume: 62 Page(s): 906 - 910
10/15/1996 Authors: Woodle ES; Cronin D; Newell KA; Millis JM; Bruce DS; Piper JB; Haas M; Josephson MA; Thistlethwaite JR -
100 living donor liver transplants: Influence of recipient size on outcome.
HEPATOLOGY Volume: 24 Page(s): 216 - 216
10/01/1996 Authors: Millis JM; Piper JB; Alonso EM; Cronin DC; Newell KA; Bruce DS; Woodle ES; McNaughton M; Thistlewaite JR; Whitington PF -
Portal vein thrombosis and stenosis in pediatric liver transplantation.
Transplantation Volume: 62 Page(s): 748 - 754
09/27/1996 Authors: Millis JM; Seaman DS; Piper JB; Alonso EM; Kelly S; Hackworth CA; Newell KA; Bruce DS; Woodle ES; Thistlethwaite JR -
Long-term outcome of kidney-pancreas transplant recipients with good graft function at one year.
Transplantation Volume: 62 Page(s): 451 - 456
08/27/1996 Authors: Bruce DS; Newell KA; Josephson MA; Woodle ES; Piper JB; Millis JM; Seaman DS; Carnrike CL; Huss E; Thistlethwaite JR -
Posttransplant lymphoproliferative disease in pediatric liver transplantation. Interplay between primary Epstein-Barr virus infection and immunosuppression.
Transplantation Volume: 62 Page(s): 370 - 375
08/15/1996 Authors: Newell KA; Alonso EM; Whitington PF; Bruce DS; Millis JM; Piper JB; Woodle ES; Kelly SM; Koeppen H; Hart J -
Outcome of monoclonal antibody induction and anti-rejection therapy in pancreas transplantation.
Transplant Proc Volume: 28 Page(s): 2136 - 2137
08/01/1996 Authors: Bruce DS; Newell KA; Woodle ES; Millis JM; Piper JB; Huss E; Thistlethwaite JR -
FK 506 therapy for refractory renal allograft rejection: lessons from liver transplantation.
Clin Transplant Volume: 10 Page(s): 323 - 332
08/01/1996 Authors: Woodle ES; Bruce DS; Josephson M; Newell KA; Piper JB; Millis JM; Cronin D; Whitman G; Ruebe M; Thistlethwaite JR -
OKT3 escalating dose regimens provide effective therapy for renal allograft rejection.
Clin Transplant Volume: 10 Page(s): 389 - 395
08/01/1996 Authors: Woodle ES; Bruce DS; Josephson M; Cronin D; Newell KA; Millis JM; Piper JB; O'Laughlin R; Thistlethwaite JR -
Tacrolimus for primary treatment of steroid-resistant hepatic allograft rejection.
Transplantation Volume: 61 Page(s): 1365 - 1369
05/15/1996 Authors: Millis JM; Woodle ES; Piper JB; Bruce DS; Newell KA; Seaman DS; Baker AL; Hart J; Dasgupta K; Thistlethwaite JR -
Role of protocol biopsies in the treatment of refractory renal allograft rejection with FK 506.
Transplant Proc Volume: 28 Page(s): 998 - 999
04/01/1996 Authors: Woodle ES; Thistlethwaite JR; Haas M; Josephson MA; Newell KA; Bruce DS; Millis JM; Piper JB; Charette JI -
Treatment of steroid-resistant rejection with tacrolimus prior to OKT3 in liver transplant recipients.
Transplant Proc Volume: 28 Page(s): 1014
04/01/1996 Authors: Millis JM; Bruce DS; Newell KA; Piper JB; Woodle ES; Seaman DS; Baker AL; Hart J; Dasgupta K; Thistlethwaite JR -
Bone marrow changes in posttransplantation lymphoproliferative disorders (PTLPD)
LABORATORY INVESTIGATION Volume: 74 Page(s): 665 - 665
01/01/1996 Authors: Koeppen H; Baunoch D; Newell K; Vardiman J -
Late complications in kidney-pancreas transplant recipients.
Transplant Proc Volume: 27 Page(s): 3118
12/01/1995 Authors: Bruce DS; Newell KA; Woodle ES; Millis JM; Piper JB; Seaman DS; Huss E; Thistlethwaite JR -
Pancreas transplantation with portal venous drainage and enteric exocrine drainage offers early advantages without compromising safety or allograft function.
Transplant Proc Volume: 27 Page(s): 3002 - 3003
12/01/1995 Authors: Newell KA; Woodle ES; Millis JM; Piper JB; Huss E; Seaman DS; Bruce DS; Thistlethwaite JR -
IMAGING OF PANCREAS TRANSPLANT - COMPARISONS OF ROUTINE AND NEW SURGICAL METHODS
Volume: 197 Page(s): 377 - 378
11/01/1995 Authors: DACHMAN AH; NEWMARK GM; NEWELL KA; THISTLETHWAITE JR; MCGILL J -
FK-506 IS AS EFFECTIVE AS OKT3 FOR INITIAL TREATMENT FOR STEROID-RESISTANT REJECTION IN LIVER-TRANSPLANT PATIENTS
HEPATOLOGY Volume: 22 Page(s): 148 - 148
10/01/1995 Authors: MILLIS JM; BRUCE DS; NEWELL KA; PIPER JB; WOODLE ES; SEAMAN DS; RAJASEKAR M; DASGUPTA K; BAKER AL; THISTLETHWAITE JR -
Changes in urinary cytokine mRNA profile after successful therapy for acute cellular renal allograft rejection.
Transplant Proc Volume: 27 Page(s): 887 - 889
02/01/1995 Authors: Jeyarajah DR; Kadakia RA; O'Toole K; Newell KA; Josephson MA; Spargo BH; Woodle ES; Thistlethwaite JR -
Liver transplantation at the University of Chicago.
Clin Transpl Page(s): 187 - 197
01/01/1995 Authors: Millis JM; Alonso EM; Piper JB; Bruce DS; Newell KA; Woodle ES; Baker AL; Whitington PF; Thistlethwaite JR -
Cooperation between staphylococcal enterotoxin B and low dose melphalan in the cure of mice bearing a large MOPC-315 tumor and extensive metastases.
J Immunol Volume: 152 Page(s): 3522 - 3529
04/01/1994 Authors: Rubin M; Bluestone JA; Newell KA; Prokhorova A; Mokyr MB -
Living related liver transplantation in children: a report of the first 58 recipients at the University of Chicago.
Transpl Int Volume: 7 Suppl 1 Page(s): S111 - S113
01/01/1994 Authors: Piper JB; Whitington PF; Woodle ES; Newell KA; Alonso EM; Thistlethwaite JR -
Involvement of TCR-V beta 8.3+ cells in the cure of mice bearing a large MOPC-315 tumor by low dose melphalan.
J Immunol Volume: 151 Page(s): 4838 - 4846
11/01/1993 Authors: Mokyr MB; Rubin M; Newell KA; Prokhorova A; Bluestone JA -
Activation of T cells in vivo using anti-CD3 and staphylococcal enterotoxins.
Int J Cancer Suppl Volume: 7 Page(s): 39 - 41
01/01/1992 Authors: Bluestone JA; Bruce DS; Newell KA -
Pediatric liver transplantation at the University of Chicago Hospitals.
Clin Transpl Page(s): 179 - 189
01/01/1992 Authors: Piper JB; Whitington PF; Woodle ES; Newell KA; Alonso EM; Emond JC; Heffron TG; Broelsch CE; Thistlethwaite JR -
IMMUNOPOTENTIATION OF ANTIVIRAL AND ANTITUMOR IMMUNE-RESPONSES USING ANTI-T-CELL RECEPTOR ANTIBODIES AND MITOGENS
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES-SERIES Volume: 636 Page(s): 279 - 287
12/30/1991 Authors: NEWELL KA; ELLENHORN JDI; HIRSCH R; BLUESTONE JA -
Immunopotentiation of anti-viral and anti-tumor immune responses using anti-T cell receptor antibodies and mitogens.
Ann N Y Acad Sci Volume: 636 Page(s): 279 - 287
12/30/1991 Authors: Newell KA; Ellenhorn JD; Hirsch R; Bluestone JA -
In vivo T-cell activation by staphylococcal enterotoxin B prevents outgrowth of a malignant tumor.
Proc Natl Acad Sci U S A Volume: 88 Page(s): 1074 - 1078
02/01/1991 Authors: Newell KA; Ellenhorn JD; Bruce DS; Bluestone JA -
Are cystgastrostomy and cystjejunostomy equivalent operations for pancreatic pseudocysts?
Surgery Volume: 108 Page(s): 635 - 639
10/01/1990 Authors: Newell KA; Liu T; Aranha GV; Prinz RA -
Adult nesidioblastosis. An unusual cause of fasting hypoglycemia.
Am Surg Volume: 55 Page(s): 366 - 369
06/01/1989 Authors: McHenry C; Newell K; Chejfec G; Barbato A; Lawrence AM; Brooks M; Emanuele MA; Paloyan E -
Plasma catecholamine changes during excision of pheochromocytoma.
Surgery Volume: 104 Page(s): 1064 - 1073
12/01/1988 Authors: Newell KA; Prinz RA; Brooks MH; Glisson SN; Barbato AL; Freeark RJ -
Pheochromocytoma multisystem crisis. A surgical emergency.
Arch Surg Volume: 123 Page(s): 956 - 959
08/01/1988 Authors: Newell KA; Prinz RA; Pickleman J; Braithwaite S; Brooks M; Karson TH; Glisson S -
Circulating concentrations of porcine ileal peptide but not hexosaminidase are elevated following 1 hr of mesenteric ischemia.
J Surg Res Volume: 45 Page(s): 134 - 139
07/01/1988 Authors: Marks WH; Salvino C; Newell K; Wider M; Marks C -
Pheochromocytoma crisis.
Am J Hypertens Volume: 1 Page(s): 189S - 191S
07/01/1988 Authors: Newell K; Prinz RA; Braithwaite S; Brooks M -
PHEOCHROMOCYTOMA CRISIS
AMERICAN JOURNAL OF HYPERTENSION Volume: 1 Page(s): S189 - S191
07/01/1988 Authors: NEWELL K; PRINZ RA; BRAITHWAITE S; BROOKS M -
CC-1065 (NSC 298223), a most potent antitumor agent: kinetics of inhibition of growth, DNA synthesis, and cell survival.
Cancer Res Volume: 42 Page(s): 3532 - 3537
09/01/1982 Authors: Bhuyan BK; Newell KA; Crampton SL; Von Hoff DD