Publications

• A Checkpoint Reversal Receptor Mediates Bipartite Activation and Enhances CAR T-cell Function.
  Cancer Res Commun Volume: 5 Page(s): 527 - 548
  03/01/2025 Authors: Landi D; Navai SA; Brock RM; Fousek K; Nawas Z; Sanber K; Chauvin-Fleurence C; Bhat RR; Xu S; Krishnamurthy P
• The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma.
  Nat Commun Volume: 16 Page(s): 1267
  02/02/2025 Authors: Banday S; Mishra AK; Rashid R; Ye T; Ali A; Li J; Yustein JT; Kelliher MA; Zhu LJ; Deibler SK
• miR-449a/miR-340 reprogram cell identity and metabolism in fusion-negative rhabdomyosarcoma.
  Cell Rep Volume: 44 Page(s): 115171
  01/28/2025 Authors: Pozzo E; Yedigaryan L; Giarratana N; Wang C-C; Garrido GM; Degreef E; Marini V; Rinaldi G; van der Veer BK; Sassi G
• Intrinsic Epigenetic State of Primary Osteosarcoma Drives Metastasis.
  Mol Cancer Res Volume: 22 Page(s): 864 - 878
  09/04/2024 Authors: Singh I; Rainusso N; Kurenbekova L; Nirala BK; Dou J; Muruganandham A; Yustein JT
• Identification of an early survival prognostic gene signature for localized osteosarcoma patients.
  Sci Rep Volume: 14 Page(s): 7327
  03/27/2024 Authors: Patel TD; Grimm SL; Kanchi RS; Gandhi T; Koirala A; Yustein JT; Coarfa C
• Systemic Cisplatin Does Not Affect the Bone Regeneration Process in a Critical Size Defect Murine Model.
  ACS Biomater Sci Eng Volume: 10 Page(s): 1646 - 1660
  03/11/2024 Authors: Brozovich AA; Lenna S; Brenner C; Serpelloni S; Paradiso F; McCulloch P; Yustein JT; Weiner B; Taraballi F
• Preclinical models for the study of pediatric solid tumors: focus on bone sarcomas.
  Front Oncol Volume: 14 Page(s): 1388484
  01/01/2024 Authors: Petrescu DI; Yustein JT; Dasgupta A
• Intrinsic epigenetic state of primary osteosarcoma drives metastasis.
  bioRxiv
  11/13/2023 Authors: Singh I; Rainusso N; Kurenbekova L; Nirala BK; Dou J; Muruganandham A; Yustein JT
• Decoding the Impact of Tumor Microenvironment in Osteosarcoma Progression and Metastasis.
  Cancers (Basel) Volume: 15
  10/23/2023 Authors: Nirala BK; Yamamichi T; Petrescu DI; Shafin TN; Yustein JT
• Deciphering the Signaling Mechanisms of Osteosarcoma Tumorigenesis.
  Int J Mol Sci Volume: 24
  07/12/2023 Authors: Nirala BK; Yamamichi T; Yustein JT
• MYC regulates CSF1 expression via microRNA 17/20a to modulate tumor-associated macrophages in osteosarcoma.
  JCI Insight Volume: 8
  07/10/2023 Authors: Nirala BK; Patel TD; Kurenbekova L; Shuck R; Dasgupta A; Rainusso N; Coarfa C; Yustein JT
• Toward quantification of hypoxia using fluorinated EuII/III-containing ratiometric probes.
  Proc Natl Acad Sci U S A Volume: 120 Page(s): e2220891120
  04/11/2023 Authors: Subasinghe SAAS; Ortiz CJ; Romero J; Ward CL; Sertage AG; Kurenbekova L; Yustein JT; Pautler RG; Allen MJ
• B7-H3-CAR T-cell therapy in immune-competent osteosarcoma models: Regnase-1 KO overcomes limited CAR T-cell expansion
  Volume: 83
  04/01/2023 Authors: Adeshakin AO; Zhou P; Metais J-Y; Nguyen P; Perry S; Sheppard H; Sun X; Cunningham T; Shi H; Wagner J
• Modeling Ewing Sarcoma Lung Metastasis.
  Curr Protoc Volume: 3 Page(s): e670
  02/01/2023 Authors: Dasgupta A; Kurenbekova L; Patel TD; Rajapakshe K; Ghosal G; Nirala B; Coarfa C; Yustein J
• Integrative metabolomics and transcriptomics analysis reveals novel therapeutic vulnerabilities in lung cancer.
  Cancer Med Volume: 12 Page(s): 584 - 596
  01/01/2023 Authors: Thaiparambil J; Dong J; Grimm SL; Perera D; Ambati CSR; Putluri V; Robertson MJ; Patel TD; Mistretta B; Gunaratne PH
• LncRNA PVT-1 promotes osteosarcoma cancer stem-like properties through direct interaction with TRIM28 and TSC2 ubiquitination.
  Oncogene Volume: 41 Page(s): 5373 - 5384
  12/01/2022 Authors: Tsang SV; Rainusso N; Liu M; Nomura M; Patel TD; Nakahata K; Kim HR; Huang S; Rajapakshe K; Coarfa C
• An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.
  NPJ Precis Oncol Volume: 6 Page(s): 65
  09/17/2022 Authors: Shulman DS; Whittle SB; Surdez D; Bailey KM; de lava E; Yustein JT; Shlien A; Hayashi M; Bishop AJR; Crompton BD
• A Mouse Holder for Awake Functional Imaging in Unanesthetized Mice: Applications in 31P Spectroscopy, Manganese-Enhanced Magnetic Resonance Imaging Studies, and Resting-State Functional Magnetic Resonance Imaging.
  Biosensors (Basel) Volume: 12
  08/08/2022 Authors: Fadel LC; Patel IV; Romero J; Tan I-C; Kesler SR; Rao V; Subasinghe SAAS; Ray RS; Yustein JT; Allen MJ
• cBAF complex components and MYC cooperate early in CD8+ T cell fate.
  Nature Volume: 607 Page(s): 135 - 141
  07/01/2022 Authors: Guo A; Huang H; Zhu Z; Chen MJ; Shi H; Yuan S; Sharma P; Connelly JP; Liedmann S; Dhungana Y
• Dual-Mode Tumor Imaging Using Probes That Are Responsive to Hypoxia-Induced Pathological Conditions.
  Biosensors (Basel) Volume: 12
  06/30/2022 Authors: Subasinghe SAAS; Pautler RG; Samee MAH; Yustein JT; Allen MJ
• Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies.
  Proc Natl Acad Sci U S A Volume: 119 Page(s): e2117857119
  04/01/2022 Authors: Tu J; Huo Z; Yu Y; Zhu D; Xu A; Huang M-F; Hu R; Wang R; Gingold JA; Chen Y-H
• CAR T-Cell Therapy Targeting ECM Proteins for Pediatric Solid Tumors
  Volume: 30 Page(s): 161 - 162
  04/01/2022 Authors: Wagner J; Wickman E; Shaw T; Tian L; Yustein J; Zhang J; Gottschalk S
• Targeting beta-catenin enhances immune checkpoint inhibition efficacy in osteosarcoma
  Volume: 113 Page(s): 1622 - 1622
  02/01/2022 Authors: Nakahata K; Nirala BK; Shuck RL; Kurenbekova L; Yustein JT
• K-Ras and p53 mouse model with molecular characteristics of human rhabdomyosarcoma and translational applications.
  Dis Model Mech Volume: 15
  02/01/2022 Authors: Nakahata K; Simons BW; Pozzo E; Shuck R; Kurenbekova L; Prudowsky Z; Dholakia K; Coarfa C; Patel TD; Donehower LA
• Osteogenesis in the presence of chemotherapy: A biomimetic approach.
  J Tissue Eng Volume: 13 Page(s): 20417314221138945
  01/01/2022 Authors: Brozovich AA; Lenna S; Paradiso F; Serpelloni S; McCulloch P; Weiner B; Yustein JT; Taraballi F
• Targeting beta-Catenin Enhances Immune Checkpoint Inhibition Efficacy in Osteosarcoma
  Volume: 68 Page(s): S250 - S250
  11/01/2021 Authors: Nakahata K; Nirala B; Kurenbekova L; Shuck R; Yustein J
• THE ROLE OF GALNT14 IN CHEMORESISTANT AND METASTATIC OSTEOSARCOMA
  Volume: 68 Page(s): S65 - S66
  06/01/2021 Authors: Prudowsky Z; Patel T; Rajakapshe K; Coarfa C; Shuck R; Rainusso N; Yustein J
• Overcoming PD-1 Inhibitor Resistance with a Monoclonal Antibody to Secreted Frizzled-Related Protein 2 in Metastatic Osteosarcoma.
  Cancers (Basel) Volume: 13
  05/30/2021 Authors: Nasarre P; Garcia DI; Siegel JB; Bonilla IV; Mukherjee R; Hilliard E; Chakraborty P; Nasarre C; Yustein JT; Lang M
• Research models and mesenchymal/epithelial plasticity of osteosarcoma.
  Cell Biosci Volume: 11 Page(s): 94
  05/22/2021 Authors: Yu X; Yustein JT; Xu J
• Immune Competent Pediatric Sarcoma Models for the Preclinical Evaluation of B7-H3-CAR T-Cell Therapy
  Volume: 29 Page(s): 326 - 326
  04/01/2021 Authors: Caldwell KJ; Phuong N; Beckett A; Haydar D; Yi Z; Krenciute G; Yustein J; Gottschalk S; DeRenzo C
• Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells.
  J Clin Invest Volume: 131
  04/01/2021 Authors: Liikanen I; Lauhan C; Quon S; Omilusik K; Phan AT; Bartrol LB; Ferry A; Goulding J; Chen J; Scott-Browne JP
• Engineering Oncolytic Vaccinia Virus to redirect Macrophages to Tumor Cells.
  Adv Cell Gene Ther Volume: 4
  04/01/2021 Authors: Cao F; Nguyen P; Hong B; DeRenzo C; Rainusso NC; Rodriguez Cruz T; Wu M-F; Liu H; Song X-T; Suzuki M
• Magnetic resonance thermometry using a GdIII-based contrast agent.
  Chem Commun (Camb) Volume: 57 Page(s): 1770 - 1773
  02/18/2021 Authors: Subasinghe SAAS; Romero J; Ward CL; Bailey MD; Zehner DR; Mehta PJ; Carniato F; Botta M; Yustein JT; Pautler RG
• p21-activated kinases as viable therapeutic targets for the treatment of high-risk Ewing sarcoma.
  Oncogene Volume: 40 Page(s): 1176 - 1190
  02/01/2021 Authors: Qasim SL; Sierra L; Shuck R; Kurenbekova L; Patel TD; Rajapakshe K; Wulff J; Nakahata K; Kim HR; Landesman Y
• Targeting PAK4 Inhibits Ras-Mediated Signaling and Multiple Oncogenic Pathways in High-Risk Rhabdomyosarcoma.
  Cancer Res Volume: 81 Page(s): 199 - 212
  01/01/2021 Authors: Dasgupta A; Sierra L; Tsang SV; Kurenbekova L; Patel T; Rajapakse K; Shuck RL; Rainusso N; Landesman Y; Unger T
• Upregulation of miR181a/miR212 Improves Myogenic Commitment in Murine Fusion-Negative Rhabdomyosarcoma.
  Front Physiol Volume: 12 Page(s): 701354
  01/01/2021 Authors: Pozzo E; Giarratana N; Sassi G; Elmastas M; Killian T; Wang C-C; Marini V; Ronzoni F; Yustein J; Uyttebroeck A
• PAK1 and PAK4 as therapeutic targets for Ewing sarcoma: a commentary.
  J Cancer Biol Volume: 2 Page(s): 94 - 97
  01/01/2021 Authors: Parks SE; Yustein JT
• Recent Insights into Therapy Resistance in Osteosarcoma.
  Cancers (Basel) Volume: 13
  12/30/2020 Authors: Prudowsky ZD; Yustein JT
• Reproducible and Characterized Method for Ponatinib Encapsulation into Biomimetic Lipid Nanoparticles as a Platform for Multi-Tyrosine Kinase-Targeted Therapy.
  ACS Appl Bio Mater Volume: 3 Page(s): 6737 - 6745
  10/19/2020 Authors: Zinger A; Baudo G; Naoi T; Giordano F; Lenna S; Massaro M; Ewing A; Kim HR; Tasciotti E; Yustein JT
• OSTEOSARCOMA EXHIBITS PATTERN OF PROTEOMIC ALTERATIONS IN RESPONSE TO HER2-SPECIFIC CAR T CELLS
  Volume: 67 Page(s): S124 - S125
  06/01/2020 Authors: Campbell M; Sanber K; Nawas Z; Joseph S; Rajapakshe K; Coarfa C; Huang S; Rainusso N; Yustein J; Ahmed N
• Imatinib revives the therapeutic potential of metformin on ewing sarcoma by attenuating tumor hypoxic response and inhibiting convergent signaling pathways.
  Cancer Lett Volume: 469 Page(s): 195 - 206
  01/28/2020 Authors: Nan X; Wang J; Cheng H; Yin Z; Sheng J; Qiu B; Lau CC; Yustein JT; Zhao H; Wong STC
• MicroRNA-509-3p inhibits cellular migration, invasion, and proliferation, and sensitizes osteosarcoma to cisplatin.
  Sci Rep Volume: 9 Page(s): 19089
  12/13/2019 Authors: Patil SL; Palat A; Pan Y; Rajapakshe K; Mirchandani R; Bondesson M; Yustein JT; Coarfa C; Gunaratne PH
• Development of a Novel Humanized Monoclonal Antibody to Secreted Frizzled-Related Protein-2 That Inhibits Triple-Negative Breast Cancer and Angiosarcoma Growth In Vivo.
  Ann Surg Oncol Volume: 26 Page(s): 4782 - 4790
  12/01/2019 Authors: Garcia D; Nasarre P; Bonilla IV; Hilliard E; Peterson YK; Spruill L; Broome A-M; Hill EG; Yustein JT; Mehrotra S
• Novel ex vivo Pulmonary Metastasis Model Using High Metastatic Pediatric Sarcoma
  Volume: 66 Page(s): S99 - S99
  12/01/2019 Authors: Nomura M; Yustein J
• Divalent Europium-Based Contrast Agents for Magnetic Resonance Imaging
  Volume: 54 Page(s): 795 - 795
  12/01/2019 Authors: Amali SA; Subasinghe S; Jiang J; Romero J; Yustein J; Pautler RG; Allen MJ
• Imatinib revives the therapeutics potential of metformin in Ewing sarcoma by attenuating tumor hypoxic response and inhibiting convergent signaling pathways
  Volume: 18
  12/01/2019 Authors: Nan X; Wang J; Sheng J; Lau CC; Yustein JT; Zhao H; Wong S
• Tegavivint and the -Catenin/ALDH Axis in Chemotherapy-Resistant and Metastatic Osteosarcoma.
  J Natl Cancer Inst Volume: 111 Page(s): 1216 - 1227
  11/01/2019 Authors: Nomura M; Rainusso N; Lee Y-C; Dawson B; Coarfa C; Han R; Larson JL; Shuck R; Kurenbekova L; Yustein JT
• INTEGRIN-MEDIATED SIGNALING AS A NOVEL THERAPEUTIC TARGET IN METASTATIC EWING SARCOMA
  Volume: 66
  06/01/2019 Authors: Wulff J; Shuck R; Kim HR; Yustein J
• INNOVATIVE 3D EX VIVO PULMONARY METASTASIS MODEL USING HIGH METASTATIC OSTEOSARCOMA PDX TUMORS
  Volume: 66
  06/01/2019 Authors: Nomura M; Rainusso N; Yustein J
• Generation of patient-derived tumor xenografts from percutaneous tumor biopsies in children with bone sarcomas.
  Pediatr Blood Cancer Volume: 66 Page(s): e27579
  04/01/2019 Authors: Rainusso N; Cleveland H; Hernandez JA; Quintanilla NM; Hicks J; Vasudevan S; Marco RAW; Allen-Rhoades W; Wang LL; Yustein JT
• Targeting SFRP2 as Novel Immunotherapy for Sarcoma
  Volume: 26 Page(s): S56 - S56
  02/01/2019 Authors: DeMore N; Nasarre P; Bonilla I; Peterson Y; Chakraborty P; Spruill L; Broome A; Hill E; Hilliard E; Yustein J
• Long non-coding RNAs regulation of therapeutic resistance.
  Cancer Drug Resist Volume: 2 Page(s): 550 - 567
  01/01/2019 Authors: Tsang S; Patel T; Yustein JT
• Emerging novel agents for patients with advanced Ewing sarcoma: a report from the Children's Oncology Group (COG) New Agents for Ewing Sarcoma Task Force.
  F1000Res Volume: 8
  01/01/2019 Authors: Bailey K; Cost C; Davis I; Glade-Bender J; Grohar P; Houghton P; Isakoff M; Stewart E; Laack N; Yustein J
• Blockade of Beta-Catenin/ALDH1 Axis Suppresses Progression and Metastasis of Osteosarcoma: Preclinical Study of a Novel WNT/Beta-Catenin Pathway Inhibitor Tegavivint
  Volume: 65 Page(s): S421 - S422
  11/01/2018 Authors: Nomura M; Rainusso N; Yustein J
• TARGETING INTEGRIN-MEDIATED SIGNALING IN METASTATIC EWING SARCOMA
  Volume: 65
  06/01/2018 Authors: Wulff J; Ghosal G; Shuck R; Kurenbekova L; Yustein J
• InVitro and InVivo Characterization of a Preclinical Irradiation-Adapted Model for Ewing Sarcoma.
  Int J Radiat Oncol Biol Phys Volume: 101 Page(s): 118 - 127
  05/01/2018 Authors: Shapiro MC; Tang T; Dasgupta A; Kurenbekova L; Shuck R; Gaber MW; Yustein JT
• Enhancer reprogramming mediates metastatic competence in osteosarcoma.
  Volume: 24 Page(s): 28 - 28
  01/01/2018 Authors: Morrow JJ; Bayles I; Funnell A; Miller TE; Saiakhova A; Lizardo MM; Bartels CF; Hung S; Hung S; Mendoza A
• Transglutaminase-2 promotes metastatic and stem-like phenotypes in osteosarcoma.
  Am J Cancer Res Volume: 8 Page(s): 1752 - 1763
  01/01/2018 Authors: Fuja DG; Rainusso NC; Shuck RL; Kurenbekova L; Donehower LA; Yustein JT
• Detection of Plasma MicroRNA Signature in Osteosarcoma Patients.
  Volume: 1699 Page(s): 113 - 118
  01/01/2018 Authors: Allen-Rhoades W; Yustein JT
• Fluorinated EuII-based multimodal contrast agent for temperature- and redox-responsive magnetic resonance imaging.
  Chem Sci Volume: 8 Page(s): 8345 - 8350
  12/01/2017 Authors: Basal LA; Bailey MD; Romero J; Ali MM; Kurenbekova L; Yustein J; Pautler RG; Allen MJ
• miR-130b directly targets ARHGAP1 to drive activation of a metastatic CDC42-PAK1-AP1 positive feedback loop in Ewing sarcoma.
  Int J Cancer Volume: 141 Page(s): 2062 - 2075
  11/15/2017 Authors: Satterfield L; Shuck R; Kurenbekova L; Allen-Rhoades W; Edwards D; Huang S; Rajapakshe K; Coarfa C; Donehower LA; Yustein JT
• Biomarker significance of plasma and tumor miR-21, miR-221, and miR-106a in osteosarcoma.
  Oncotarget Volume: 8 Page(s): 96738 - 96752
  11/14/2017 Authors: Nakka M; Allen-Rhoades W; Li Y; Kelly AJ; Shen J; Taylor AM; Barkauskas DA; Yustein JT; Andrulis IL; Wunder JS
• Metabolic modulation of Ewing sarcoma cells inhibits tumor growth and stem cell properties.
  Oncotarget Volume: 8 Page(s): 77292 - 77308
  09/29/2017 Authors: Dasgupta A; Trucco M; Rainusso N; Bernardi RJ; Shuck R; Kurenbekova L; Loeb DM; Yustein JT
• Biomarker significance of plasma and tumor miR-21, miR-221, and miR-106a in pediatric osteosarcoma
  Volume: 77
  07/01/2017 Authors: Nakka M; Allen-Rhoades W; Li Y; Kelly A; Shen J; Taylor A; Barkauskas DA; Yustein J; Andrulis I; Wunder J
• Radiation-Adapted Ewing Sarcoma Xenograft Mouse Model Demonstrates Decreased Sensitivity to Ionizing Radiation Therapy
  Volume: 64 Page(s): S45 - S45
  06/01/2017 Authors: Shapiro M; Tang T; Coarfa C; Rajapakshe K; Shuck R; Kurenbekova L; Gaber MW; Yustein J
• Targeting Integrin-Mediated Signaling in Metastatic Ewing Sarcoma
  Volume: 64 Page(s): S3 - S4
  06/01/2017 Authors: Wulff J; Ghosal G; Shuck R; Kurenbekova L; Thuy P; Yustein J
• Cancer's Achilles' Heel: Apoptosis and Necroptosis to the Rescue.
  Int J Mol Sci Volume: 18
  12/23/2016 Authors: Dasgupta A; Nomura M; Shuck R; Yustein J
• Secreted Frizzled-Related Protein 2 (sFRP2) promotes osteosarcoma invasion and metastatic potential.
  BMC Cancer Volume: 16 Page(s): 869
  11/08/2016 Authors: Techavichit P; Gao Y; Kurenbekova L; Shuck R; Donehower LA; Yustein JT
• Glycolysis determines dichotomous regulation of T cell subsets in hypoxia.
  J Clin Invest Volume: 126 Page(s): 2678 - 2688
  07/01/2016 Authors: Xu Y; Chaudhury A; Zhang M; Savoldo B; Metelitsa LS; Rodgers J; Yustein JT; Neilson JR; Dotti G
• THE ROLE OF INTEGRIN BETA-3 AND INTEGRIN SIGNALING IN DRIVING METASTATIC EWING SARCOMA
  Volume: 63 Page(s): S65 - S66
  06/01/2016 Authors: Wulff J; Yustein J; Ghosal G; Shuck R; Kurenbekova L
• IDENTIFICATION OF MOLECULAR ABERRATIONS CONTRIBUTING TO BONE SARCOMA RADIOTHERAPEUTIC RESISTANCE
  Volume: 63 Page(s): S66 - S66
  06/01/2016 Authors: Carroll M; Gaber MW; Coarfa C; Rajapakshe K; Shuck R; Kurenbekova L; Tang T; Yustein J
• Targeting pediatric bone sarcoma stem cell with metabolic inhibitors
  Volume: 14
  01/01/2016 Authors: Trucco M; Rainsusso N; Techavichit P; Bernardi R; Shuck R; Satterfield L; Allen-Rhoades W; Donehower L; Loeb D; Yustein J
• Coamplification of Myc/Pvt1 and homozygous deletion of Nlrp1 locus are frequent genetics changes in mouse osteosarcoma.
  Genes Chromosomes Cancer Volume: 54 Page(s): 796 - 808
  12/01/2015 Authors: Rao PH; Zhao S; Zhao Y-J; Yu A; Rainusso N; Trucco M; Allen-Rhoades W; Satterfield L; Fuja D; Borra VJ
• Loss of Runx2 sensitises osteosarcoma to chemotherapy-induced apoptosis.
  Br J Cancer Volume: 113 Page(s): 1289 - 1297
  11/03/2015 Authors: Roos A; Satterfield L; Zhao S; Fuja D; Shuck R; Hicks MJ; Donehower LA; Yustein JT
• CO-AMPLIFICATION OF MYC/PVT1 AND HOMOZYGOUS DELETION OF NLRP1 LOCUS ARE THE FREQUENT GENETICS CHANGES IN MOUSE OSTEOSARCOMA
  Volume: 62 Page(s): S214 - S214
  11/01/2015 Authors: Rao P; Kurenbekova L; Zhao YJ; Yu A; Rainusso N; Trucco M; Allen-Rhoades W; Borra V; Man TK; Donehower L
• NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma.
  Oncogene Volume: 34 Page(s): 5069 - 5079
  09/24/2015 Authors: Zhao S; Kurenbekova L; Gao Y; Roos A; Creighton CJ; Rao P; Hicks J; Man T-K; Lau C; Brown AMC
• miR-130b targets Arhgap1 increasing Cdc42 activity and metastic potential in Ewing sarcoma cells
  Volume: 75
  08/01/2015 Authors: Satterfield L; Kurenbekova L; Shuck R; Donehower L; Yustein J
• Cross-species identification of a plasma microRNA signature for detection, therapeutic monitoring, and prognosis in osteosarcoma.
  Cancer Med Volume: 4 Page(s): 977 - 988
  07/01/2015 Authors: Allen-Rhoades W; Kurenbekova L; Satterfield L; Parikh N; Fuja D; Shuck RL; Rainusso N; Trucco M; Barkauskas DA; Jo E
• Mouse models to study cancer stem cells in osteosarcoma.
  Volume: 32
  05/20/2014 Authors: Rainusso NC; Kurenbekova L; Donehower L; Rosen J; Yustein JT
• The adolescent and young adult with cancer: state of the art -- bone tumors.
  Curr Oncol Rep Volume: 15 Page(s): 296 - 307
  08/01/2013 Authors: Rainusso N; Wang LL; Yustein JT
• ChIP-PED enhances the analysis of ChIP-seq and ChIP-chip data.
  Bioinformatics Volume: 29 Page(s): 1182 - 1189
  05/01/2013 Authors: Wu G; Yustein JT; McCall MN; Zilliox M; Irizarry RA; Zeller K; Dang CV; Ji H
• Oncogenic role of Runx2 in the development of osteosarcoma.
  Volume: 73
  04/15/2013 Authors: Roos A; Yustein JT; Donehower L
• Novel mouse models to investigate the molecular pathogenesis of metastatic osteosarcoma
  Volume: 73
  04/15/2013 Authors: Zhao S; Kurenbekova L; Donehower LA; Yustein JT
• PROTEOGLYCAN 4 EXPRESSION PROTECTS AGAINST THE DEVELOPMENT OF OSTEOARTHRITIS
  Volume: 21 Page(s): S18 - S18
  04/01/2013 Authors: Ruan MZ; Erez A; Guse K; Dawson B; Bertin T; Chen Y; Jiang M-M; Yustein J; Gannon F; Lee B
• Proteoglycan 4 expression protects against the development of osteoarthritis.
  Sci Transl Med Volume: 5 Page(s): 176ra34
  03/13/2013 Authors: Ruan MZC; Erez A; Guse K; Dawson B; Bertin T; Chen Y; Jiang M-M; Yustein J; Gannon F; Lee BHL
• Multiple target-specific molecular agents for detection and image analysis of breast cancer characteristics in mice.
  Curr Mol Med Volume: 13 Page(s): 446 - 458
  03/01/2013 Authors: Ke S; Wang W; Qiu X; Zhang F; Yustein JT; Cameron AG; Zhang S; Yu D; Zou C; Gao X
• Tumor Suppressive Function of MicroRNA34c in Osteosarcoma
  Volume: 28
  02/01/2013 Authors: Bae Y; Zeng H-C; Tao J; Wang L; Yustein J; Lee B
• Characterization of metastatic cancer stem cells in osteosarcoma
  Volume: 73
  02/01/2013 Authors: Rainusso N; Kurenbekova L; Donehower L; Rosen J; Yustein J
• Novel mouse models to investigate the molecular pathogenesis of metastatic osteosarcoma
  Volume: 73
  02/01/2013 Authors: Zhao S; Kurenbekova L; Donehower LA; Yustein JT
• NOVEL MOUSE MODELS TO INVESTIGATE THE MOLECULAR PATHOGENESIS OF METASTATIC OSTEOSARCOMA
  Volume: 58 Page(s): 1019 - 1019
  07/01/2012 Authors: Yustein J; Zhao S; Satterfield L; Gao Y; Kurenbekova L; Donehower L
• High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition.
  PLoS One Volume: 5 Page(s): e13943
  11/11/2010 Authors: Awad O; Yustein JT; Shah P; Gul N; Katuri V; O'Neill A; Kong Y; Brown ML; Toretsky JA; Loeb DM
• Abdominal undifferentiated small round cell tumor with unique translocation (X;19)(q13;q13.3).
  Pediatr Blood Cancer Volume: 54 Page(s): 1041 - 1044
  07/01/2010 Authors: Yustein JT; Rednam S; Bertuch AA; Goss JA; Brandt ML; Eldin K; Lu X; Hicks J
• High aldehyde dehydrogenase activity identifies a chemotherapy-resistant population of ewing's sarcoma cells with a stem cell phenotype that retains sensitivity to EWS-FLI1 inhibition
  Volume: 70
  04/01/2010 Authors: Awad O; Yustein JT; Shah P; Gul N; Rotenberg JB; Toretsky J; Loeb D
• Induction of ectopic Myc target gene JAG2 augments hypoxic growth and tumorigenesis in a human B-cell model.
  Proc Natl Acad Sci U S A Volume: 107 Page(s): 3534 - 3539
  02/23/2010 Authors: Yustein JT; Liu Y-C; Gao P; Jie C; Le A; Vuica-Ross M; Chng WJ; Eberhart CG; Bergsagel PL; Dang CV
• The interplay between MYC and HIF in cancer.
  Nat Rev Cancer Volume: 8 Page(s): 51 - 56
  01/01/2008 Authors: Dang CV; Kim J-W; Gao P; Yustein J
• Biology and treatment of Burkitt's lymphoma.
  Curr Opin Hematol Volume: 14 Page(s): 375 - 381
  07/01/2007 Authors: Yustein JT; Dang CV
• Global mapping of c-Myc binding sites and target gene networks in human B cells.
  Proc Natl Acad Sci U S A Volume: 103 Page(s): 17834 - 17839
  11/21/2006 Authors: Zeller KI; Zhao X; Lee CWH; Chiu KP; Yao F; Yustein JT; Ooi HS; Orlov YL; Shahab A; Yong HC
• Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis.
  Mol Cell Biol Volume: 25 Page(s): 6225 - 6234
  07/01/2005 Authors: Li F; Wang Y; Zeller KI; Potter JJ; Wonsey DR; O'Donnell KA; Kim J-W; Yustein JT; Lee LA; Dang CV
• Poly(ADP-ribose) polymerase 1 and Ste20-like kinase hKFC act as transcriptional repressors for gamma-2 herpesvirus lytic replication.
  Mol Cell Biol Volume: 23 Page(s): 8282 - 8294
  11/01/2003 Authors: Gwack Y; Nakamura H; Lee SH; Souvlis J; Yustein JT; Gygi S; Kung H-J; Jung JU
• Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38.
  Oncogene Volume: 22 Page(s): 6129 - 6141
  09/18/2003 Authors: Yustein JT; Xia L; Kahlenburg JM; Robinson D; Templeton D; Kung H-J
• KFC, a Ste20-like kinase with mitogenic potential and capability to activate the SAPK/JNK pathway.
  Oncogene Volume: 19 Page(s): 710 - 718
  02/03/2000 Authors: Yustein JT; Li D; Robinson D; Kung HJ
• Tyrosine kinase expression profiles of chicken erythro-progenitor cells and oncogene-transformed erythroblasts.
  J Biomed Sci Volume: 5 Page(s): 93 - 100
  01/01/1998 Authors: Robinson D; Chen HC; Li D; Yustein JT; He F; Lin WC; Hayman MJ; Kung HJ