Jennifer Wong
- Department of Human Genetics
Assistant Professor
-
Emory Children's Center (ECC)
Pediatrics
2015 Uppergate Drive
Overview
Research Interests
The overall focus of my research is to understand the effect of seizures on molecular dynamics and neural function in the brain and how dysfunction in these processes contributes to epileptogenesis and, ultimately, the development of epilepsy. By increasing our understanding of epileptogenesis, we will identify molecular and neural targets for the development of novel treatments for epilepsy and its associated behavioral abnormalities, and potentially other neurological disorders. To approach these issues, I use mouse models (both genetic and acquired epilepsy) to evaluate the long-term effect of early-life seizures on seizures and behavior. These mouse models also provide the opportunity to investigate the therapeutic potential of established anti-epileptic drugs and novel treatments.
Academic Appointment
- Assistant Professor, Pediatrics, Emory University School of Medicine
- Assistant Professor, Human Genetics, Emory University School of Medicine
Education
Degrees
- B.S., Biology from University of Georgia
- Ph.D., Neuroscience from University of Georgia
Research
Publications
-
Microfluidics-Assisted Formulation of Polymeric Oxytocin Nanoparticles for Targeted Brain Delivery.
Pharmaceutics Volume: 17
04/01/2025 Authors: Adediran E; Vijayanand S; Kale A; Gulani M; Wong JC; Escayg A; Murnane KS; D'Souza MJ -
WONOEP appraisal: Targeted therapy development for early onset epilepsies.
Epilepsia Volume: 66 Page(s): 328 - 340
02/01/2025 Authors: Casillas-Espinosa PM; Wong JC; Grabon W; Gonzalez-Ramos A; Mantegazza M; Yilmaz NC; Patel M; Staley K; Sankar R; O'Brien TJ -
Knock, Knock, Who's There? Not SCN1A in Brain Organoids.
Epilepsy Curr Volume: 25 Page(s): 133 - 135
01/01/2025 Authors: Wong JC -
MicroRNA 335-5p: The Sodium Channel Silencer.
Epilepsy Curr Volume: 24 Page(s): 50 - 52
01/01/2024 Authors: Wong JC -
Carvedilol increases seizure resistance in a mouse model of SCN8A-derived epilepsy.
Front Pharmacol Volume: 15 Page(s): 1397225
01/01/2024 Authors: Wong JC; Escayg A -
Drinking from the fountain of youth for mTOR-related epilepsy.
Epilepsy Curr Volume: 24 Page(s): 434 - 436
01/01/2024 Authors: Wong JC -
Dopamine Dilemma Overexcites the Hippocampus in Alzheimer's Disease.
Epilepsy Curr Volume: 24 Page(s): 361 - 363
01/01/2024 Authors: Wong JC -
Generation and initial characterization of mice lacking full-length BAI3 (ADGRB3) expression.
Basic Clin Pharmacol Toxicol Volume: 133 Page(s): 353 - 363
10/01/2023 Authors: Shiu FH; Wong JC; Bhattacharya D; Kuranaga Y; Parag RR; Alsharif HA; Bhatnagar S; Van Meir EG; Escayg A -
Gaining Awareness of Increasingly Persistent SCN1A Mutations.
Epilepsy Curr Volume: 23 Page(s): 179 - 181
01/01/2023 Authors: Wong JC -
Cannabidiol Keeps Hippocampal Hyperactivity in Check.
Epilepsy Curr Volume: 23 Page(s): 318 - 320
01/01/2023 Authors: Wong JC