Jon Willie
Academic Appointment
- Assistant Professor, Neurosurgery, Emory University, Atlanta
- Assistant Professor, Neurology, Emory University, Atlanta
Education
Degrees
- MD from University of Texas Southwestern Medical Center, Dallas
- PhD from University of Texas Southwestern Medical Center, Dallas
- BA from University of Texas at Austin, Austin
Research
Focus
- As a physician-scientist and academic neurosurgeon, I seek to develop novel interventional therapies for neurological disorders. Understanding mechanisms of arousal is a not only a fundamental problem in neuroscience, but also a daily clinical problem in neurology and neurosurgery. The orexin/hypocretin neuropeptide transmitter system critically orchestrates the activity of multiple brain circuits to produce sustained wake and motivation. Loss of orexin neurons of the hypothalamus causes the sleep-wake disorder narcolepsy with cataplexy.
Publications
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The case for hemispheric lateralization of the human amygdala in fear processing.
Mol Psychiatry Volume: 30 Page(s): 2252 - 2259
05/01/2025 Authors: Xie T; van Rooij SJH; Inman CS; Wang S; Brunner P; Willie JT -
Cost-Effectiveness Analysis of Early Minimally Invasive Removal of Intracerebral Hemorrhage.
Stroke
04/25/2025 Authors: Hanmer J; Arnold J; Hall A; Ratcliff JJ; Allen JW; Frankel M; Wright DW; Barrow DL; Pradilla G; Smith KJ -
A neural computational framework for face processing in the human temporal lobe.
Curr Biol Volume: 35 Page(s): 1765 - 1778.e6
04/21/2025 Authors: Cao R; Zhang J; Zheng J; Wang Y; Brunner P; Willie JT; Wang S -
The human brainstem's red nucleus was upgraded to support goal-directed action.
Nat Commun Volume: 16 Page(s): 3398
04/10/2025 Authors: Krimmel SR; Laumann TO; Chauvin RJ; Hershey T; Roland JL; Shimony JS; Willie JT; Norris SA; Marek S; N Van A -
Long-Term Outcome of Unilateral Magnetic Resonance Imaging-Guided Focused Ultrasound for Fragile X Tremor Ataxia Syndrome.
Mov Disord Clin Pract
03/29/2025 Authors: Di Luca DG; Ushe M; Norris SA; Alfradique-Dunham I; Glasser M; Nazeri A; Kotzbauer P; Willie JT -
Direct MRI-guided stereotactic radiofrequency thermal ablation for mesial temporal lobe epilepsy: illustrative cases.
J Neurosurg Case Lessons Volume: 9
03/10/2025 Authors: Bhole S; Maccotta L; Aum DJ; Hinrichs KH; Nascimento FA; Willie JT -
A neuronal code for object representation and memory in the human amygdala and hippocampus.
Nat Commun Volume: 16 Page(s): 1510
02/10/2025 Authors: Cao R; Brunner P; Chakravarthula PN; Wahlstrom KL; Inman C; Smith EH; Li X; Mamelak AN; Brandmeir NJ; Rutishauser U -
A single-center learning curve for stereotactic laser amygdalohippocampotomy and a surgical framework to manage failures.
Epilepsia Volume: 66 Page(s): 458 - 470
02/01/2025 Authors: Raghu ALB; Lau J; Stern MA; Faraj RR; Isbaine F; Grogan D; Bullinger K; Roth RW; Dickey AS; Willie JT -
Exploring individual differences in amygdala-mediated memory modulation.
Cogn Affect Behav Neurosci Volume: 25 Page(s): 188 - 209
02/01/2025 Authors: Hollearn MK; Manns JR; Blanpain LT; Hamann SB; Bijanki K; Gross RE; Drane DL; Campbell JM; Wahlstrom KL; Light GF -
A human single-neuron dataset for object recognition.
Sci Data Volume: 12 Page(s): 79
01/15/2025 Authors: Cao R; Brunner P; Brandmeir NJ; Willie JT; Wang S