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Profile

Jon Willie

  • Department of Neurosurgery
    Adjunct Assistant Professor
  • jon.t.willie@emory.edu
Head shot of Jon Willie

Academic Appointment

  • Assistant Professor, Neurosurgery, Emory University, Atlanta
  • Assistant Professor, Neurology, Emory University, Atlanta

Education

Degrees

  • MD from University of Texas Southwestern Medical Center, Dallas
  • PhD from University of Texas Southwestern Medical Center, Dallas
  • BA from University of Texas at Austin, Austin

Research

Focus

  • As a physician-scientist and academic neurosurgeon, I seek to develop novel interventional therapies for neurological disorders. Understanding mechanisms of arousal is a not only a fundamental problem in neuroscience, but also a daily clinical problem in neurology and neurosurgery. The orexin/hypocretin neuropeptide transmitter system critically orchestrates the activity of multiple brain circuits to produce sustained wake and motivation. Loss of orexin neurons of the hypothalamus causes the sleep-wake disorder narcolepsy with cataplexy.

Publications

  • The case for hemispheric lateralization of the human amygdala in fear processing.
    Mol Psychiatry Volume: 30 Page(s): 2252 - 2259
    05/01/2025 Authors: Xie T; van Rooij SJH; Inman CS; Wang S; Brunner P; Willie JT
  • Cost-Effectiveness Analysis of Early Minimally Invasive Removal of Intracerebral Hemorrhage.
    Stroke
    04/25/2025 Authors: Hanmer J; Arnold J; Hall A; Ratcliff JJ; Allen JW; Frankel M; Wright DW; Barrow DL; Pradilla G; Smith KJ
  • A neural computational framework for face processing in the human temporal lobe.
    Curr Biol Volume: 35 Page(s): 1765 - 1778.e6
    04/21/2025 Authors: Cao R; Zhang J; Zheng J; Wang Y; Brunner P; Willie JT; Wang S
  • The human brainstem's red nucleus was upgraded to support goal-directed action.
    Nat Commun Volume: 16 Page(s): 3398
    04/10/2025 Authors: Krimmel SR; Laumann TO; Chauvin RJ; Hershey T; Roland JL; Shimony JS; Willie JT; Norris SA; Marek S; N Van A
  • Long-Term Outcome of Unilateral Magnetic Resonance Imaging-Guided Focused Ultrasound for Fragile X Tremor Ataxia Syndrome.
    Mov Disord Clin Pract
    03/29/2025 Authors: Di Luca DG; Ushe M; Norris SA; Alfradique-Dunham I; Glasser M; Nazeri A; Kotzbauer P; Willie JT
  • Direct MRI-guided stereotactic radiofrequency thermal ablation for mesial temporal lobe epilepsy: illustrative cases.
    J Neurosurg Case Lessons Volume: 9
    03/10/2025 Authors: Bhole S; Maccotta L; Aum DJ; Hinrichs KH; Nascimento FA; Willie JT
  • A neuronal code for object representation and memory in the human amygdala and hippocampus.
    Nat Commun Volume: 16 Page(s): 1510
    02/10/2025 Authors: Cao R; Brunner P; Chakravarthula PN; Wahlstrom KL; Inman C; Smith EH; Li X; Mamelak AN; Brandmeir NJ; Rutishauser U
  • A single-center learning curve for stereotactic laser amygdalohippocampotomy and a surgical framework to manage failures.
    Epilepsia Volume: 66 Page(s): 458 - 470
    02/01/2025 Authors: Raghu ALB; Lau J; Stern MA; Faraj RR; Isbaine F; Grogan D; Bullinger K; Roth RW; Dickey AS; Willie JT
  • Exploring individual differences in amygdala-mediated memory modulation.
    Cogn Affect Behav Neurosci Volume: 25 Page(s): 188 - 209
    02/01/2025 Authors: Hollearn MK; Manns JR; Blanpain LT; Hamann SB; Bijanki K; Gross RE; Drane DL; Campbell JM; Wahlstrom KL; Light GF
  • A human single-neuron dataset for object recognition.
    Sci Data Volume: 12 Page(s): 79
    01/15/2025 Authors: Cao R; Brunner P; Brandmeir NJ; Willie JT; Wang S
  • Neural pathway activation in the subthalamic region depends on stimulation polarity.
    Brain Commun Volume: 7 Page(s): fcaf006
    01/01/2025 Authors: Borgheai SB; Opri E; Isbaine F; Cole ER; Jafari Deligani R; Laxpati NG; Risk BB; Willie JT; Gross RE; AuYong N
  • Characterizing the Prevalence of Psychiatric Conditions and Fear-Potentiated Startle Response in Civilians with a History of Trauma and Seizures.
    Chronic Stress (Thousand Oaks) Volume: 9 Page(s): 24705470251321953
    01/01/2025 Authors: Prochaska T; Zeleke H; Minton ST; Powers A; Michopoulos V; Willie JT; Drane DL; Jovanovic T; van Rooij SJH
  • Optimal hippocampal targeting in responsive neurostimulation for mesial temporal lobe epilepsy.
    J Neurosurg Volume: 141 Page(s): 1105 - 1114
    10/01/2024 Authors: Skelton HM; Bullinger K; Isbaine F; Lau JC; Willie JT; Gross RE
  • Neural populations in the language network differ in the size of their temporal receptive windows.
    Nat Hum Behav Volume: 8 Page(s): 1924 - 1942
    10/01/2024 Authors: Regev TI; Casto C; Hosseini EA; Adamek M; Ritaccio AL; Willie JT; Brunner P; Fedorenko E
  • Novel cyclic homogeneous oscillation detection method for high accuracy and specific characterization of neural dynamics.
    Elife Volume: 12
    09/06/2024 Authors: Cho H; Adamek M; Willie JT; Brunner P
  • An ordinal clinical score predicts seizure freedom after minimally invasive epilepsy surgery.
    Ann Clin Transl Neurol Volume: 11 Page(s): 2327 - 2336
    09/01/2024 Authors: Dickey AS; Bullinger KL; Grogan D; Asmar MM; Alwaki A; Kheder A; Shivamurthy VKN; Faraj RR; Greven A; Willie JT
  • FDG-PET/MRI in the presurgical evaluation of pediatric epilepsy.
    Pediatr Radiol Volume: 54 Page(s): 1589 - 1602
    09/01/2024 Authors: Ponisio MR; Zempel JM; Willie JT; Tomko SR; McEvoy SD; Roland JL; Williams JP
  • Impact of white matter networks on risk for memory decline following resection versus ablation in temporal lobe epilepsy.
    J Neurol Neurosurg Psychiatry Volume: 95 Page(s): 663 - 670
    06/17/2024 Authors: Kaestner E; Stasenko A; Schadler A; Roth R; Hewitt K; Reyes A; Qiu D; Bonilha L; Voets N; Hu R
  • Comparison of minimally invasive to standard temporal lobectomy approaches to epilepsy surgery: Seizure relief and visual confrontation naming outcomes.
    Epilepsy Behav Volume: 155 Page(s): 109669
    06/01/2024 Authors: Hageboutros K; Hewitt KC; Lee GP; Bansal A; Block C; Pedersen NP; Willie JT; Loring DW; Schoenberg MR; Smith KA
  • Graded decisions in the human brain.
    Nat Commun Volume: 15 Page(s): 4308
    05/21/2024 Authors: Xie T; Adamek M; Cho H; Adamo MA; Ritaccio AL; Willie JT; Brunner P; Kubanek J
  • Multisensory flicker modulates widespread brain networks and reduces interictal epileptiform discharges.
    Nat Commun Volume: 15 Page(s): 3156
    04/11/2024 Authors: Blanpain LT; Cole ER; Chen E; Park JK; Walelign MY; Gross RE; Cabaniss BT; Willie JT; Singer AC
  • Neural mechanisms of face familiarity and learning in the human amygdala and hippocampus.
    Cell Rep Volume: 43 Page(s): 113520
    01/23/2024 Authors: Cao R; Wang J; Brunner P; Willie JT; Li X; Rutishauser U; Brandmeir NJ; Wang S
  • The brainstem's red nucleus was evolutionarily upgraded to support goal-directed action.
    bioRxiv
    01/01/2024 Authors: Krimmel SR; Laumann TO; Chauvin RJ; Hershey T; Roland JL; Shimony JS; Willie JT; Norris SA; Marek S; Van AN
  • Does vibrotactile stimulation of the auricular vagus nerve enhance working memory? A behavioral and physiological investigation.
    Brain Stimul Volume: 17 Page(s): 460 - 468
    01/01/2024 Authors: Tan G; Adams J; Donovan K; Demarest P; Willie JT; Brunner P; Gorlewicz JL; Leuthardt EC
  • The involvement of the piriform cortex in non-lesional temporal lobe epilepsy: an uncommon component of the epileptogenic network.
    Brain Commun Volume: 6 Page(s): fcae179
    01/01/2024 Authors: Pedersen NP; Raghu A; Shivamurthy VKN; Chern JJ; Gross RE; Willie JT; Dingledine RJ; Kheder A
  • Combination of or Transition between Deep Brain Stimulation and Responsive Neurostimulation for the Treatment of Drug-Resistant Epilepsy.
    Stereotact Funct Neurosurg Volume: 102 Page(s): 345 - 355
    01/01/2024 Authors: Yang JC; Skelton H; Isbaine F; Bullinger KL; Alwaki A; Cabaniss BT; Willie JT; Gross RE
  • Single-pulse electrical stimulation artifact removal using the novel matching pursuit-based artifact reconstruction and removal method (MPARRM).
    J Neural Eng Volume: 20
    12/27/2023 Authors: Xie T; Foutz TJ; Adamek M; Swift JR; Inman CS; Manns JR; Leuthardt EC; Willie JT; Brunner P
  • Intracranial stimulation and EEG feature analysis reveal affective salience network specialization.
    Brain Volume: 146 Page(s): 4366 - 4377
    10/03/2023 Authors: Metzger BA; Kalva P; Mocchi MM; Cui B; Adkinson JA; Wang Z; Mathura R; Kanja K; Gavvala J; Krishnan V
  • A pilot study of lymphoscintigraphy with tracer injection into the human brain.
    J Cereb Blood Flow Metab Volume: 43 Page(s): 1382 - 1389
    08/01/2023 Authors: Coxon AT; Desai R; Patel PR; Vellimana AK; Willie JT; Dowling JL; Leuthardt EC; Kim AH; Johanns TM; Siegel BA
  • Stereoelectroencephalography-guided radiofrequency ablation of the epileptogenic zone as a treatment and predictor of future success of further surgical intervention.
    Epilepsia Volume: 64 Page(s): 2081 - 2093
    08/01/2023 Authors: Shields JA; Greven ACM; Shivamurthy VKN; Dickey AS; Matthews RE; Laxpati NG; Alwaki A; Drane DL; Isbaine F; Willie JT
  • Withdrawal of antiseizure medications after MRI-Guided laser interstitial thermal therapy in extra-temporal lobe epilepsy.
    Seizure Volume: 110 Page(s): 86 - 92
    08/01/2023 Authors: Athreya A; Matthews RE; Drane DL; Bonilha L; Willie JT; Gross RE; Karakis I
  • Psychiatric changes after stereotactic laser amygdalohippocampotomy for medial temporal lobe epilepsy.
    Epilepsy Behav Volume: 145 Page(s): 109332
    08/01/2023 Authors: Padda K; Matthews RE; Karakis I; Hewitt KC; Valentin E; Block C; Shade T; Dickey A; Millis S; Willie JT
  • Reply: Deep Brain Stimulation Outcomes in Parkinson's Disease Patients with Cognitive Impairment: Implications and Considerations.
    Mov Disord Clin Pract Volume: 10 Page(s): 1235 - 1236
    08/01/2023 Authors: Block CK; Patel M; Risk BB; Staikova E; Loring D; Esper CD; Scorr L; Higginbotham L; Aia P; De Long MR
  • Slow-wave modulation analysis during states of unconsciousness using the novel tau-modulation method.
    J Neural Eng Volume: 20
    07/21/2023 Authors: Xie T; Wu Z; Foutz TJ; Sheng X; Zhu X; Leuthardt EC; Willie JT; Chen L; Brunner P
  • Unilateral amygdala ablation: a potential treatment option for severe chronic post-traumatic stress disorder (PTSD)?
    Expert Rev Neurother Volume: 23 Page(s): 483 - 486
    06/01/2023 Authors: Teye-Botchway L; Willie JT; van Rooij SJH
  • The effect of responsive neurostimulation (RNS) on neuropsychiatric and psychosocial outcomes in drug-resistant epilepsy.
    Epilepsy Behav Volume: 142 Page(s): 109207
    05/01/2023 Authors: Tager D; Panjeti-Moore D; Yang JC; Rivera-Cruz A; Loring DW; Staikova E; Block C; Bullinger KL; Rodriguez-Ruiz AA; Cabaniss BT
  • A somato-cognitive action network alternates with effector regions in motor cortex.
    Nature Volume: 617 Page(s): 351 - 359
    05/01/2023 Authors: Gordon EM; Chauvin RJ; Van AN; Rajesh A; Nielsen A; Newbold DJ; Lynch CJ; Seider NA; Krimmel SR; Scheidter KM
  • Complication rate of overlapping versus nonoverlapping functional and stereotactic surgery: a retrospective cohort study.
    J Neurosurg Volume: 138 Page(s): 1043 - 1049
    04/01/2023 Authors: Greven ACM; Douglas JM; Nakirikanti AS; Malcolm JG; Campbell M; Easley KA; Laxpati NG; Lamanna JJ; Bray DP; Howard BM
  • Multisensory Flicker Modulates Widespread Brain Networks and Reduces Interictal Epileptiform Discharges in Humans.
    medRxiv
    03/17/2023 Authors: Blanpain LT; Chen E; Park J; Walelign MY; Gross RE; Cabaniss BT; Willie JT; Singer AC
  • Patients with Cognitive Impairment in Parkinson's Disease Benefit from Deep Brain Stimulation: A Case-Control Study.
    Mov Disord Clin Pract Volume: 10 Page(s): 382 - 391
    03/01/2023 Authors: Block CK; Patel M; Risk BB; Staikova E; Loring D; Esper CD; Scorr L; Higginbotham L; Aia P; DeLong MR
  • BrainWAVE: A Flexible Method for Noninvasive Stimulation of Brain Rhythms across Species.
    eNeuro Volume: 10
    02/01/2023 Authors: Attokaren MK; Jeong N; Blanpain L; Paulson AL; Garza KM; Borron B; Walelign M; Willie J; Singer AC
  • Association Between Anatomical Location of Surgically Induced Lesions and Postoperative Seizure Outcome in Temporal Lobe Epilepsy.
    Neurology Volume: 100 Page(s): 265
    01/31/2023
  • A multicenter retrospective study of patients treated in the thalamus with responsive neurostimulation.
    Front Neurol Volume: 14 Page(s): 1202631
    01/01/2023 Authors: Fields MC; Eka O; Schreckinger C; Dugan P; Asaad WF; Blum AS; Bullinger K; Willie JT; Burdette DE; Anderson C
  • Centromedian thalamic deep brain stimulation for drug-resistant epilepsy: single-center experience.
    J Neurosurg Volume: 137 Page(s): 1591 - 1600
    12/01/2022 Authors: Yang JC; Bullinger KL; Isbaine F; Alwaki A; Opri E; Willie JT; Gross RE
  • A Neurosurgery Case Series on the Role of the Amygdala and Temporal Pole in Development and Maintenance of PTSD
    Volume: 47 Page(s): 102 - 103
    12/01/2022 Authors: van Rooij S; Minton S; Ely T; Hinojosa C; Harnett N; Powers A; Jovanovic T; Drane D; Bijanki K; Willie J
  • Vagus nerve stimulation paired with rehabilitation for stroke: Implantation experience from the VNS-REHAB trial.
    J Clin Neurosci Volume: 105 Page(s): 122 - 128
    11/01/2022 Authors: Liu CY; Russin J; Adelson DP; Jenkins A; Hilmi O; Brown B; Lega B; Whitworth T; Bhattacharyya D; Schwartz TH
  • The Effect of Responsive Neurostimulation (RNS) on Cognitive, Psychiatric and Quality of Life Outcomes in Drug-Resistant Epilepsy
    Volume: 92 Page(s): S92 - S93
    10/01/2022 Authors: Tager D; Panjeti-Moore D; Wang JC; Rivera-Cruz A; Loring DW; Staikova E; Block CK; Bullinger KL; Rodriguez-Ruiz AA; Cabaniss BT
  • Anterior nucleus of the thalamus deep brain stimulation vs temporal lobe responsive neurostimulation for temporal lobe epilepsy.
    Epilepsia Volume: 63 Page(s): 2290 - 2300
    09/01/2022 Authors: Yang JC; Bullinger KL; Dickey AS; Karakis I; Alwaki A; Cabaniss BT; Winkel D; Rodriguez-Ruiz A; Willie JT; Gross RE
  • Meta-optimization to select stimulation settings for Deep Brain Stimulation in Parkinson's disease
    Volume: 37 Page(s): S189 - S189
    09/01/2022 Authors: Connolly M; Isbaine F; Willie J; Gross R; Devergnas A; Miocinovic S
  • The Referential Montage Inadequately Localizes Corticocortical Evoked Potentials in Stereoelectroencephalography.
    J Clin Neurophysiol Volume: 39 Page(s): 412 - 418
    07/01/2022 Authors: Dickey AS; Alwaki A; Kheder A; Willie JT; Drane DL; Pedersen NP
  • Open surgery or laser interstitial thermal therapy for low-grade epilepsy-associated tumors of the temporal lobe: A single-institution consecutive series.
    Epilepsy Behav Volume: 130 Page(s): 108659
    05/01/2022 Authors: Hedaya AA; Hewitt KC; Hu R; Epstein CM; Gross RE; Drane DL; Willie JT
  • Overlapping Functional and Stereotactic Surgery: A Retrospective Cohort Study of 1-Year Complications
    Volume: 68 Page(s): 61 - 62
    04/01/2022 Authors: Greven ACM; Douglas JAM; Malcolm JG; Campbell M; Lamanna JJ; Bray DP; Howard BM; Willie JT; Boulis NM; Gross RE
  • Association Between Anatomical Location of Surgically Induced Lesions and Postoperative Seizure Outcome in Temporal Lobe Epilepsy.
    Neurology Volume: 98 Page(s): e141 - e151
    01/11/2022 Authors: Gleichgerrcht E; Drane DL; Keller SS; Davis KA; Gross R; Willie JT; Pedersen N; de Bezenac C; Jensen J; Weber B
  • Protocol for the Ketamine for Postoperative Avoidance of Depressive Symptoms (K-PASS) feasibility study: A randomized clinical trial.
    F1000Res Volume: 11 Page(s): 510
    01/01/2022 Authors: Fritz BA; Tellor Pennington BR; Palanca BJA; Schweiger JA; Willie JT; Farber NB
  • Withdrawal of antiepileptic drugs after stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy.
    Epilepsy Res Volume: 176 Page(s): 106721
    10/01/2021 Authors: Athreya A; Fasano RE; Drane DL; Millis SR; Willie JT; Gross RE; Karakis I
  • Increased Amplitude of Corticocortical Evoked Potentials Predicts the Site of Epilepsy Surgery
    Volume: 90 Page(s): S109 - S110
    10/01/2021 Authors: Dickey A; Willie JT; Vosoughi A; Gross RE; Pedersen NP
  • Non-Invasive Deep Brain Modulation in Humans via Rhythmic Sensory Stimulation
    Volume: 90 Page(s): S88 - S88
    10/01/2021 Authors: Blanpain LT; Walelign MY; Park JK; Chen E; Willie JT; Singer AC
  • Feasibility and Morbidity of Magnetic Resonance Imaging-Guided Stereotactic Laser Ablation of Deep Cerebral Cavernous Malformations: A Report of 4 Cases.
    Neurosurgery Volume: 89 Page(s): 635 - 644
    09/15/2021 Authors: Malcolm JG; Douglas JM; Greven A; Rich C; Dawoud RA; Hu R; Reisner A; Barrow DL; Gross RE; Willie JT
  • MRI-guided stereotactic laser corpus callosotomy for epilepsy: distinct methods and outcomes.
    J Neurosurg Volume: 135 Page(s): 770 - 782
    09/01/2021 Authors: Rich CW; Fasano RE; Isbaine F; Saindane AM; Qiu D; Curry DJ; Gross RE; Willie JT
  • Reduced gray-white matter contrast localizes the motor cortex on double inversion recovery (DIR) 3T MRI.
    Neuroradiology Volume: 63 Page(s): 1071 - 1078
    07/01/2021 Authors: Joshi H; Hoch MJ; Braileanu M; Gore A; Willie JT; Hu R
  • Multi-objective data-driven optimization for improving deep brain stimulation in Parkinson's disease.
    J Neural Eng Volume: 18
    05/05/2021 Authors: Connolly MJ; Cole ER; Isbaine F; de Hemptinne C; Starr PA; Willie JT; Gross RE; Miocinovic S
  • Continuous Intraoperative Neurophysiological Monitoring of the Motor Pathways Using Depth Electrodes During Surgical Resection of an Epileptogenic Lesion: A Novel Technique.
    Oper Neurosurg (Hagerstown) Volume: 20 Page(s): E379 - E385
    04/15/2021 Authors: Chen DF; Willie JT; Cabrera D; Bullinger KL; Karakis I
  • In Reply: Case Series: Unilateral Amygdala Ablation Ameliorates Post-Traumatic Stress Disorder Symptoms and Biomarkers.
    Neurosurgery Volume: 88 Page(s): E480 - E481
    04/15/2021 Authors: van Rooij SJH; Bijanki KR; Willie JT
  • Antiepileptic Drugs Use after Deep Brain Stimulation Therapy
    Volume: 96
    04/13/2021 Authors: Phillips H; Ladha H; Bullinger K; Alwaki A; Willie J; Gross R; Karakis I
  • Clinical outcomes of globus pallidus deep brain stimulation for Parkinson disease: a comparison of intraoperative MRI- and MER-guided lead placement.
    J Neurosurg Volume: 134 Page(s): 1072 - 1082
    03/01/2021 Authors: Bezchlibnyk YB; Sharma VD; Naik KB; Isbaine F; Gale JT; Cheng J; Triche SD; Miocinovic S; Buetefisch CM; Willie JT
  • Image-based biophysical modeling predicts cortical potentials evoked with subthalamic deep brain stimulation.
    Brain Stimul Volume: 14 Page(s): 549 - 563
    01/01/2021 Authors: Howell B; Isbaine F; Willie JT; Opri E; Gross RE; De Hemptinne C; Starr PA; McIntyre CC; Miocinovic S
  • Identifying the neurophysiological effects of memory-enhancing amygdala stimulation using interpretable machine learning.
    Brain Stimul Volume: 14 Page(s): 1511 - 1519
    01/01/2021 Authors: Sendi MSE; Inman CS; Bijanki KR; Blanpain L; Park JK; Hamann S; Gross RE; Willie JT; Mahmoudi B
  • Superior Verbal Memory Outcome After Stereotactic Laser Amygdalohippocampotomy.
    Front Neurol Volume: 12 Page(s): 779495
    01/01/2021 Authors: Drane DL; Willie JT; Pedersen NP; Qiu D; Voets NL; Millis SR; Soares BP; Saindane AM; Hu R; Kim MS
  • Clinical outcomes of pallidal deep brain stimulation for dystonia implanted using intraoperative MRI.
    J Neurosurg Volume: 133 Page(s): 1582 - 1594
    11/01/2020 Authors: Sharma VD; Bezchlibnyk YB; Isbaine F; Naik KB; Cheng J; Gale JT; Miocinovic S; Buetefisch C; Factor SA; Willie JT
  • An Approach to the Analysis and Successful Treatment of Epilepsy Due to Periventricular Nodular Heterotopia - Corticocortical Evoked Potentials, Signal Processing and Radiofrequency Ablation
    Volume: 88 Page(s): S128 - S128
    10/01/2020 Authors: Shivamurthy VKN; Dickey AS; Ladha HS; Willie JT; Kheder A; Pedersen NP
  • Optimizing Patient-Specific Computational Models of DBS Using Intraoperative Electrocorticography
    Volume: 88 Page(s): S177 - S177
    10/01/2020 Authors: Howell B; Isbaine F; Willie JT; Opri E; Gross RE; De Hemptinne C; Starr PA; McIntyre CC; Miocinovic S
  • The Referential Montage Poorly Localizes Cortico-Cortical Evoked Potentials
    Volume: 88 Page(s): S128 - S128
    10/01/2020 Authors: Dickey A; Alwaki A; Kheder A; Gross R; Willie J; Drane D; Pedersen N
  • Case Series: Unilateral Amygdala Ablation Ameliorates Post-Traumatic Stress Disorder Symptoms and Biomarkers.
    Neurosurgery Volume: 87 Page(s): 796 - 802
    09/15/2020 Authors: Bijanki KR; van Rooij SJH; Ely TD; Stevens JS; Inman CS; Fasano RE; Carter SE; Winters SJ; Baman JR; Drane DL
  • Letter: Magnetic Resonance Imaging-Guided Laser Interstitial Thermal Therapy for Epilepsy: Systematic Review of Technique, Indications, and Outcomes.
    Neurosurgery Volume: 87 Page(s): E438 - E439
    09/01/2020 Authors: Stern MA; Malcolm JG; Willie JT; Gross RE; Drane DL
  • Magnetic resonance-guided laser interstitial thermal therapy for posterior fossa neoplasms.
    J Neurooncol Volume: 149 Page(s): 533 - 542
    09/01/2020 Authors: Ashraf O; Arzumanov G; Luther E; McMahon JT; Malcolm JG; Mansour S; Lee IY; Willie JT; Komotar RJ; Danish SF
  • Human amygdala stimulation effects on emotion physiology and emotional experience.
    Neuropsychologia Volume: 145 Page(s): 106722
    08/01/2020 Authors: Inman CS; Bijanki KR; Bass DI; Gross RE; Hamann S; Willie JT
  • Stereotactic MRI-guided laser interstitial thermal therapy for extratemporal lobe epilepsy.
    Epilepsia Volume: 61 Page(s): 1723 - 1734
    08/01/2020 Authors: Gupta K; Cabaniss B; Kheder A; Gedela S; Koch P; Hewitt KC; Alwaki A; Rich C; Ramesha S; Hu R
  • Amygdala Stimulation Leads to Functional Network Connectivity State Transitions in the Hippocampus.
    Volume: 2020 Page(s): 3625 - 3628
    07/01/2020 Authors: Sendi MSE; Kanta V; Inman CS; Manns JR; Hamann S; Gross RE; Willie JT; Mahmoudi B
  • Functionally distinct high and low theta oscillations in the human hippocampus.
    Nat Commun Volume: 11 Page(s): 2469
    05/18/2020 Authors: Goyal A; Miller J; Qasim SE; Watrous AJ; Zhang H; Stein JM; Inman CS; Gross RE; Willie JT; Lega B
  • Supervised and unsupervised machine learning for automated scoring of sleep-wake and cataplexy in a mouse model of narcolepsy.
    Sleep Volume: 43
    05/12/2020 Authors: Exarchos I; Rogers AA; Aiani LM; Gross RE; Clifford GD; Pedersen NP; Willie JT
  • Withdrawal of Antiepileptic Drugs After Stereotactic Laser Amygdalohippocampotomy
    Volume: 94
    04/14/2020 Authors: Athreya A; Willie J; Gross R; Fasano R; Karakis I
  • Unilateral Laser Amygdalohippocampotomy Ameliorates PTSD Symptoms and Biomarkers
    Volume: 132 Page(s): 119 - 119
    04/01/2020 Authors: Willie JT; Bijanki K; van Rooij S; Fasano R; Drane D; Jovanovic T
  • Single-Neuron Representations of Spatial Targets in Humans.
    Curr Biol Volume: 30 Page(s): 245 - 253.e4
    01/20/2020 Authors: Tsitsiklis M; Miller J; Qasim SE; Inman CS; Gross RE; Willie JT; Smith EH; Sheth SA; Schevon CA; Sperling MR
  • Computer-assisted planning for minimally invasive anterior two-thirds laser corpus callosotomy: A feasibility study with probabilistic tractography validation.
    Neuroimage Clin Volume: 25 Page(s): 102174
    01/01/2020 Authors: Vakharia VN; Sparks RE; Vos SB; Bezchlibnyk Y; Mehta AD; Willie JT; Wu C; Sharan A; Ourselin S; Duncan JS
  • Deep brain stimulation of hypothalamus for narcolepsy-cataplexy in mice.
    Brain Stimul Volume: 13 Page(s): 1305 - 1316
    01/01/2020 Authors: Rogers AA; Aiani LM; Blanpain LT; Yuxian S; Moore R; Willie JT
  • Robot Assisted MRI-Guided LITT of the Anterior, Lateral, and Medial Temporal Lobe for Temporal Lobe Epilepsy.
    Front Neurol Volume: 11 Page(s): 572334
    01/01/2020 Authors: Gupta K; Dickey AS; Hu R; Faught E; Willie JT
  • Memory retrieval modulates spatial tuning of single neurons in the human entorhinal cortex.
    Nat Neurosci Volume: 22 Page(s): 2078 - 2086
    12/01/2019 Authors: Qasim SE; Miller J; Inman CS; Gross RE; Willie JT; Lega B; Lin J-J; Sharan A; Wu C; Sperling MR
  • Stereoelectroencephalography-Guided Laser Interstitial Thermal Therapy (SEEGgLITT) for Temporal Lobe Epilepsy Associated with Encephaloceles
    Volume: 86 Page(s): S160 - S161
    10/01/2019 Authors: Rich CW; Hu R; Gross RE; Cabaniss BT; Willie JT
  • EFFECTS OF HUMAN AMYGDALA STIMULATION AND ABLATION ON EMOTIONAL PHYSIOLOGY, MEMORY, AND PTSD
    Volume: 56 Page(s): S7 - S7
    09/01/2019 Authors: Willie J; Inman C
  • Mapping the Neural Basis of Declarative Verbal Memory: Evidence from Mesial Temporal Lobe Lesions
    Volume: 92
    04/09/2019 Authors: Gleichgerrcht EL; Bonilha L; Qiu D; Leatherday C; Voets N; Pedersen N; Loring D; Willie JT; Gross R; Drane D
  • Cingulum stimulation enhances positive affect and anxiolysis to facilitate awake craniotomy.
    J Clin Invest Volume: 129 Page(s): 1152 - 1166
    03/01/2019 Authors: Bijanki KR; Manns JR; Inman CS; Choi KS; Harati S; Pedersen NP; Drane DL; Waters AC; Fasano RE; Mayberg HS
  • Safety and effectiveness of stereotactic laser ablation for epileptogenic cerebral cavernous malformations.
    Epilepsia Volume: 60 Page(s): 220 - 232
    02/01/2019 Authors: Willie JT; Malcolm JG; Stern MA; Lowder LO; Neill SG; Cabaniss BT; Drane DL; Gross RE
  • Mechanisms and Risk Factors Contributing to Visual Field Deficits following Stereotactic Laser Amygdalohippocampotomy.
    Stereotact Funct Neurosurg Volume: 97 Page(s): 255 - 265
    01/01/2019 Authors: Voets NL; Alvarez I; Qiu D; Leatherday C; Willie JT; Sotiropoulos S; Gleichgerrcht E; Bonilha L; Pedersen NP; Kadom N
  • Amygdala Ablation: A Neurosurgical Approach to PTSD Treatment?
    Volume: 43 Page(s): S466 - S467
    12/01/2018 Authors: van Rooij S; Bijanki K; Inman C; Carter S; Ely T; Jovanovic T; Willie J
  • Cortical Potentials Evoked by Subthalamic Stimulation Demonstrate a Short Latency Hyperdirect Pathway in Humans.
    J Neurosci Volume: 38 Page(s): 9129 - 9141
    10/24/2018 Authors: Miocinovic S; de Hemptinne C; Chen W; Isbaine F; Willie JT; Ostrem JL; Starr PA
  • Dorsal Anterior Cingulum Bundle Stimulation: Impact on Positive Affect, Anxiolysis, and Analgesia across Twenty Patients
    Volume: 84 Page(s): S145 - S146
    10/01/2018 Authors: Bijanki KR; Manns JR; Gale JT; Choi KS; Inman CS; Mayberg HS; Drane DL; Willie JT
  • Focal Ablations of the Amygdala and Hippocampus Infrequently Results in Verbal Memory Impairment
    ANNALS OF NEUROLOGY Volume: 84 Page(s): S173 - S173
    10/01/2018 Authors: Drane DL; Willie J; Pedersen NP; Soares BP; Qiu D; Millis S; Saindane AM; Loring DW; Voets NL; Grabowski T
  • Correlation between Corticocortical Evoked Potential Amplitude and Ictal Propagation Pattern Predicts the Ablation Zone during Surgery for Refractory Epilepsy
    Volume: 84 Page(s): S75 - S75
    10/01/2018 Authors: Dickey A; Willie J; Isbane F; Fasano R; Cabaniss B; Gross R; Gale J; Pedersen N
  • Direct Electrical Stimulation of the Lateral Hypothalamic Area Consolidates Wake and Ameliorates Cataplexy in a Mouse Model of Narcolepsy Type 1
    Volume: 84 Page(s): S231 - S231
    10/01/2018 Authors: Willie JT; Rogers AA; Aiani LM; Pedersen NP
  • Charting the road forward in psychiatric neurosurgery: proceedings of the 2016 American Society for Stereotactic and Functional Neurosurgery workshop on neuromodulation for psychiatric disorders.
    J Neurol Neurosurg Psychiatry Volume: 89 Page(s): 886 - 896
    08/01/2018 Authors: Bari AA; Mikell CB; Abosch A; Ben-Haim S; Buchanan RJ; Burton AW; Carcieri S; Cosgrove GR; D'Haese P-F; Daskalakis ZJ
  • A neurosurgeon`s view: Laser interstitial thermal therapy of mesial temporal lobe structures.
    Epilepsy Res Volume: 142 Page(s): 135 - 139
    05/01/2018 Authors: Bezchlibnyk YB; Willie JT; Gross RE
  • DIRECT ELECTRICAL STIMULATION OF THE LATERAL HYPOTHALAMUS CONSOLIDATES WAKE AND AMELIORATES CATAPLEXY IN A MOUSE MODEL OF NARCOLEPSY TYPE 1
    Volume: 41 Page(s): A60 - A60
    04/01/2018 Authors: Rogers A; Aiani L; Pedersen N; Willie J
  • BRIEF HYPERSYNCHRONOUS PAROXYSMAL THETA BURSTS DURING WAKE PRECEDE SUBSEQUENT SLEEP AND CATAPLEXY IN MOUSE NARCOLEPSY TYPE 1
    Volume: 41 Page(s): A61 - A61
    04/01/2018 Authors: Rogers A; Aiani L; Pedersen N; Willie J
  • Stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy.
    Ann Neurol Volume: 83 Page(s): 575 - 587
    03/01/2018 Authors: Gross RE; Stern MA; Willie JT; Fasano RE; Saindane AM; Soares BP; Pedersen NP; Drane DL
  • Direct electrical stimulation of the amygdala enhances declarative memory in humans.
    Proc Natl Acad Sci U S A Volume: 115 Page(s): 98 - 103
    01/02/2018 Authors: Inman CS; Manns JR; Bijanki KR; Bass DI; Hamann S; Drane DL; Fasano RE; Kovach CK; Gross RE; Willie JT
  • MRI-guided stereotactic neurosurgical procedures in a diagnostic MRI suite: Background and safe practice recommendations.
    J Healthc Risk Manag Volume: 37 Page(s): 31 - 39
    07/01/2017 Authors: Larson PS; Willie JT; Vadivelu S; Azmi-Ghadimi H; Nichols A; Fauerbach LL; Johnson HB; Graham D
  • Deep brain stimulation of the centromedian thalamic nucleus for essential tremor: a case report.
    Acta Neurochir (Wien) Volume: 159 Page(s): 789 - 793
    05/01/2017 Authors: Sharma VD; Mewes K; Wichmann T; Buetefisch C; Willie JT; DeLong M
  • Stereotactic Laser Amygdalohippocampotomy for Pharmaco-resistant Mesial Temporal Lobe Epilepsy: One-Year Outcomes in a Large Series
    JOURNAL OF NEUROSURGERY Volume: 126 Page(s): A1438 - A1438
    04/01/2017 Authors: Stern MA; Willie J; Drane D; Fasano R; Saindane A; Soares B; Gross R; Pedersen N
  • Role of hippocampus in human memory redefined: Evidence from stereotactic laser amygdalohippocampotomy
    JOURNAL OF NEUROSURGERY Volume: 126 Page(s): A1440 - A1440
    04/01/2017 Authors: Drane DL; Willie J; Soares B; Qiu D; Saindane A; Loring D; Voets N; Ojemann J; Kim M; Meador K
  • DIRECT ELECTRICAL STIMULATION TO THE HUMAN AMYGDALA ENHANCES RECOGNITION MEMORY FOLLOWING SLEEP
    Volume: 40 Page(s): A87 - A87
    04/01/2017 Authors: Willie JT; Inman CS; Bijanki KR; Gross RE; Hamann S; Manns JR
  • Restoring Conscious Arousal During Focal Limbic Seizures with Deep Brain Stimulation.
    Cereb Cortex Volume: 27 Page(s): 1964 - 1975
    03/01/2017 Authors: Kundishora AJ; Gummadavelli A; Ma C; Liu M; McCafferty C; Schiff ND; Willie JT; Gross RE; Gerrard J; Blumenfeld H
  • Laser Interstitial Thermal Therapy for Mesial Temporal Lobe Epilepsy.
    Neurosurgery Volume: 79 Suppl 1 Page(s): S83 - S91
    12/01/2016 Authors: Wicks RT; Jermakowicz WJ; Jagid JR; Couture DE; Willie JT; Laxton AW; Gross RE
  • Laser Interstitial Thermal Therapy Technology, Physics of Magnetic Resonance Imaging Thermometry, and Technical Considerations for Proper Catheter Placement During Magnetic Resonance Imaging-Guided Laser Interstitial Thermal Therapy.
    Neurosurgery Volume: 79 Suppl 1 Page(s): S8 - S16
    12/01/2016 Authors: Patel NV; Mian M; Stafford RJ; Nahed BV; Willie JT; Gross RE; Danish SF
  • Clinical Outcomes Of Deep Brain Stimulation Placement Using Intraoperative MRI for Parkinson Disease
    Volume: 86
    04/05/2016 Authors: Sharma V; Naik K; Buetefisch C; Triche S; Willie J; Boulis N; Factor S; Gross R; DeLong M
  • Deep Brain Stimulation Placement Using Intraoperative MRI for Dystonia: One Year Clinical Outcomes
    Volume: 86
    04/05/2016 Authors: Sharma V; Naik K; Triche S; Buetefisch C; Willie J; Boulis N; Factor S; Gross R; DeLong M
  • Deep Brain Stimulation Placement Using Intraoperative MRI for Dystonia: One Year Clinical Outcomes
    Volume: 86
    04/05/2016 Authors: Sharma V; Naik K; Triche S; Buetefisch C; Willie J; Boulis N; Factor S; Gross R; DeLong M
  • Deep Brain Stimulation Placement Using Intraoperative MRI for Dystonia: One Year Clinical Outcomes
    Volume: 86
    04/05/2016 Authors: Sharma V; Naik K; Triche S; Buetefisch C; Willie J; Boulis N; Factor S; Gross R; DeLong M
  • Deep Brain Stimulation Placement Using Intraoperative MRI for Dystonia: One Year Clinical Outcomes
    Volume: 86
    04/05/2016 Authors: Sharma V; Naik K; Triche S; Buetefisch C; Willie J; Boulis N; Factor S; Gross R; DeLong M
  • Deep Brain Stimulation Placement Using Intraoperative MRI for Dystonia: One Year Clinical Outcomes
    Volume: 86
    04/05/2016 Authors: Sharma V; Naik K; Triche S; Buetefisch C; Willie J; Boulis N; Factor S; Gross R; DeLong M
  • Clinical Outcomes Of Deep Brain Stimulation Placement Using Intraoperative MRI for Parkinson Disease
    Volume: 86
    04/05/2016 Authors: Sharma V; Naik K; Buetefisch C; Triche S; Willie J; Boulis N; Factor S; Gross R; DeLong M
  • Deep Brain Stimulation Placement Using Intraoperative MRI for Dystonia: One Year Clinical Outcomes
    Volume: 86
    04/05/2016 Authors: Sharma V; Naik K; Triche S; Buetefisch C; Willie J; Boulis N; Factor S; Gross R; DeLong M
  • Deep Brain Stimulation Placement Using Intraoperative MRI for Dystonia: One Year Clinical Outcomes
    Volume: 86
    04/05/2016 Authors: Sharma V; Naik K; Triche S; Buetefisch C; Willie J; Boulis N; Factor S; Gross R; DeLong M
  • Magnetic Resonance Thermometry-Guided Stereotactic Laser Ablation of Cavernous Malformations in Drug-Resistant Epilepsy: Imaging and Clinical Results.
    Oper Neurosurg (Hagerstown) Volume: 12 Page(s): 39 - 48
    03/01/2016 Authors: McCracken DJ; Willie JT; Fernald BA; Saindane AM; Drane DL; Barrow DL; Gross RE
  • The Role of Stereotactic Laser Amygdalohippocampotomy in Mesial Temporal Lobe Epilepsy.
    Neurosurg Clin N Am Volume: 27 Page(s): 37 - 50
    01/01/2016 Authors: Gross RE; Willie JT; Drane DL
  • Magnetic Resonance Thermometry-Guided Stereotactic Laser Ablation of Cavernous Malformations in Drug-Resistant Epilepsy: Imaging and Clinical Results.
    Neurosurgery
    09/25/2015 Authors: McCracken DJ; Willie JT; Fernald BA; Saindane AM; Drane DL; Barrow DL; Gross RE
  • Response to Journal Club: Real-time Magnetic Resonance-Guided Stereotactic Laser Amygdalohippocampotomy for Mesial Temporal Lobe Epilepsy.
    Neurosurgery Volume: 77 Page(s): E502 - E504
    09/01/2015 Authors: Gross RE; Willie JT
  • 202Role of Repeat Ablation to Treat Seizure Recurrence Following Stereotactic Laser Amygdalohippocampotomy.
    Neurosurgery Volume: 62 Suppl 1 Page(s): 233 - 234
    08/01/2015 Authors: Willie JT; Gross RE
  • In response: Naming and recognition after laser amygdalohippocampotomy: Is the hippocampus involved?
    Epilepsia Volume: 56 Page(s): 1318 - 1319
    08/01/2015 Authors: Drane DL; Loring DW; Voets NL; Price M; Ojemann JG; Willie JT; Saindane AM; Phatak V; Ivanisevic M; Millis S
  • Neurostimulation to improve level of consciousness in patients with epilepsy.
    Neurosurg Focus Volume: 38 Page(s): E10
    06/01/2015 Authors: Gummadavelli A; Kundishora AJ; Willie JT; Andrews JP; Gerrard JL; Spencer DD; Blumenfeld H
  • Temporal profile of improvement of tardive dystonia after globus pallidus deep brain stimulation.
    Parkinsonism Relat Disord Volume: 21 Page(s): 116 - 119
    02/01/2015 Authors: Shaikh AG; Mewes K; DeLong MR; Gross RE; Triche SD; Jinnah HA; Boulis N; Willie JT; Freeman A; Alexander GE
  • Better object recognition and naming outcome with MRI-guided stereotactic laser amygdalohippocampotomy for temporal lobe epilepsy.
    Epilepsia Volume: 56 Page(s): 101 - 113
    01/01/2015 Authors: Drane DL; Loring DW; Voets NL; Price M; Ojemann JG; Willie JT; Saindane AM; Phatak V; Ivanisevic M; Millis S
  • Application of high-frequency Granger causality to analysis of epileptic seizures and surgical decision making.
    Epilepsia Volume: 55 Page(s): 2038 - 2047
    12/01/2014 Authors: Epstein CM; Adhikari BM; Gross R; Willie J; Dhamala M
  • Frameless Stereotactic Drilling for Placement of Depth Electrodes in Refractory Epilepsy: Operative Technique and Initial Experience COMMENT
    OPERATIVE NEUROSURGERY Volume: 10 Page(s): 590 - 591
    12/01/2014 Authors: Willie JT
  • Frameless stereotactic drilling for placement of depth electrodes in refractory epilepsy: operative technique and initial experience.
    Neurosurgery Volume: 10 Suppl 4 Page(s): 582 - 590
    12/01/2014 Authors: Dorfer C; Stefanits H; Pataraia E; Wolfsberger S; Feucht M; Baumgartner C; Czech T
  • 103Stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy: collective experience from 7 single-center, prospective, investigator-initiated studies.
    Neurosurgery Volume: 61 Suppl 1 Page(s): 192
    08/01/2014 Authors: Gross RE; Willie JT; Sharan AD; Sperling M; Shih JJ; Wharen RE; Tatum W; Popli G; Couture DE; Laxton AW
  • Real-time magnetic resonance-guided stereotactic laser amygdalohippocampotomy for mesial temporal lobe epilepsy.
    Neurosurgery Volume: 74 Page(s): 569 - 584
    06/01/2014 Authors: Willie JT; Laxpati NG; Drane DL; Gowda A; Appin C; Hao C; Brat DJ; Helmers SL; Saindane A; Nour SG
  • Interventaional MRI and anatomical 3D-model-guided DBS placement in globus pallidus internus for Parkinson's disease and dystonia
    Volume: 29 Page(s): S451 - S452
    05/01/2014 Authors: Shaikh AG; Mewes K; Gross RE; Willie JT; Boulis N; DeLong MR
  • Beyond therapeutic nihilism? The neurosurgical treatment of intracerebral hemorrhage.
    World Neurosurg Volume: 80 Page(s): e135 - e137
    11/01/2013 Authors: Willie JT; Gross RE
  • MULTICENTER EXPERIENCE WITH MINIMALLY INVASIVE STEREOTACTIC LASER THERMAL AMYGDALOHIPPOCAMPOTOMY FOR MESIAL TEMPORAL LOBE EPILEPSY
    Volume: 54 Page(s): 290 - 290
    06/01/2013 Authors: Willie JT; Gross RE; Mehta A; Sharan A; Sperling MR; Curry DJ; Wilfong A; Marsh WR; Danish SF; Wong S
  • SHORT-TERM HEALTHCARE UTILIZATION IN STEREOTACTIC MRI-GUIDED LASER ABLATION FOR TREATMENT OF MESIAL TEMPORAL LOBE EPILEPSY
    Volume: 54 Page(s): 190 - 190
    06/01/2013 Authors: Helmers SL; Gross RE; Willie JT
  • Real-Time MRI-Guided Stereotactic Laser Thermal Amygdalohippocampotomy (SLTAH) for Refractory Mesial Temporal Lobe Epilepsy
    NEUROLOGY Volume: 80
    02/12/2013 Authors: Korb P; Willie J; Laxpati N; Saindane A; Nour S; Gowda A; Gross R
  • Stereotactic Laser Ablation of Epileptic Foci: A Novel, Minimally Invasive Technique for Intractable Epilepsy
    STEREOTACTIC AND FUNCTIONAL NEUROSURGERY Volume: 91 Page(s): 7 - 7
    01/01/2013 Authors: Willie JT; Gowda A; Saindane A; Nour S; Gross RE
  • The baric probe: a novel long-term implantable intracranial pressure monitor with ultrasound-based interrogation.
    J Neurosurg Pediatr Volume: 10 Page(s): 518 - 524
    12/01/2012 Authors: Limbrick DD; Lake S; Talcott M; Alexander B; Wight S; Willie JT; Richard WD; Genin GM; Leuthardt EC
  • Controlled cortical impact traumatic brain injury acutely disrupts wakefulness and extracellular orexin dynamics as determined by intracerebral microdialysis in mice.
    J Neurotrauma Volume: 29 Page(s): 1908 - 1921
    07/01/2012 Authors: Willie JT; Lim MM; Bennett RE; Azarion AA; Schwetye KE; Brody DL
  • Reversible obstructive hydrocephalus from hypertensive encephalopathy.
    Neurocrit Care Volume: 16 Page(s): 433 - 439
    06/01/2012 Authors: Kumar A; Keyrouz SG; Willie JT; Dhar R
  • Cholinergic modulation of narcoleptic attacks in double orexin receptor knockout mice.
    PLoS One Volume: 6 Page(s): e18697
    04/13/2011 Authors: Kalogiannis M; Hsu E; Willie JT; Chemelli RM; Kisanuki YY; Yanagisawa M; Leonard CS
  • Sexual intercourse and cerebral aneurysmal rupture: potential mechanisms and precipitants.
    J Neurosurg Volume: 114 Page(s): 969 - 977
    04/01/2011 Authors: Reynolds MR; Willie JT; Zipfel GJ; Dacey RG
  • Ectopic overexpression of orexin alters sleep/wakefulness states and muscle tone regulation during REM sleep in mice.
    J Mol Neurosci Volume: 43 Page(s): 155 - 161
    02/01/2011 Authors: Willie JT; Takahira H; Shibahara M; Hara J; Nomiyama M; Yanagisawa M; Sakurai T
  • BRAIN OREXIN LEVELS CORRELATE WITH WAKEFULNESS IN A MOUSE MODEL OF TRAUMATIC BRAIN INJURY
    Volume: 34 Page(s): A38 - A38
    01/01/2011 Authors: Lim MM; Willie JT; Azarion AA; Smith R; Schwetye KE; Brody DL
  • Determination of Orexin Neuropeptide Dynamics by Brain Microdialysis Following Traumatic Brain Injury in Mice
    Volume: 113 Page(s): A421 - A422
    08/01/2010 Authors: Willie JT; Schwetye KE; Brody DL
  • Histamine-1 receptor is not required as a downstream effector of orexin-2 receptor in maintenance of basal sleep/wake states.
    Acta Physiol (Oxf) Volume: 198 Page(s): 287 - 294
    03/01/2010 Authors: Hondo M; Nagai K; Ohno K; Kisanuki Y; Willie JT; Watanabe T; Yanagisawa M; Sakurai T
  • Enhanced Orexin Neuropeptide Signaling Prevents Features of Metabolic Syndrome in Mice: 967.
    Volume: 65 Page(s): 422 - 423
    08/01/2009 Authors: Willie JT; Funato H; Sakurai T; Yanagisawa M
  • Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity.
    Cell Metab Volume: 9 Page(s): 64 - 76
    01/07/2009 Authors: Funato H; Tsai AL; Willie JT; Kisanuki Y; Williams SC; Sakurai T; Yanagisawa M
  • A consensus definition of cataplexy in mouse models of narcolepsy.
    Sleep Volume: 32 Page(s): 111 - 116
    01/01/2009 Authors: Scammell TE; Willie JT; Guilleminault C; Siegel JM; International Working Group on Rodent Models of Narcolepsy
  • Abnormal response of melanin-concentrating hormone deficient mice to fasting: hyperactivity and rapid eye movement sleep suppression.
    Neuroscience Volume: 156 Page(s): 819 - 829
    10/28/2008 Authors: Willie JT; Sinton CM; Maratos-Flier E; Yanagisawa M
  • Dependence of subarachnoid hemorrhage on climate conditions: A systematic meteorological analysis from the Dusseldorf metropolitan area - Comments
    NEUROSURGERY Volume: 62 Page(s): 1038 - 1039
    05/01/2008 Authors: Willie JT; Dacey RG; Hodge CJ; Findlay JM; Meyer B; Harnof S; Fernandez-Miranda JC; Kassell NF; Kitchen N
  • Modafinil more effectively induces wakefulness in orexin-null mice than in wild-type littermates.
    Neuroscience Volume: 130 Page(s): 983 - 995
    01/01/2005 Authors: Willie JT; Renthal W; Chemelli RM; Miller MS; Scammell TE; Yanagisawa M; Sinton CM
  • Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice.
    Proc Natl Acad Sci U S A Volume: 101 Page(s): 4649 - 4654
    03/30/2004 Authors: Mieda M; Willie JT; Hara J; Sinton CM; Sakurai T; Yanagisawa M
  • Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes.
    Neuron Volume: 38 Page(s): 715 - 730
    06/05/2003 Authors: Willie JT; Chemelli RM; Sinton CM; Tokita S; Williams SC; Kisanuki YY; Marcus JN; Lee C; Elmquist JK; Kohlmeier KA
  • Hypothalamic orexin neurons regulate arousal according to energy balance in mice.
    Neuron Volume: 38 Page(s): 701 - 713
    06/05/2003 Authors: Yamanaka A; Beuckmann CT; Willie JT; Hara J; Tsujino N; Mieda M; Tominaga M; Yagami KI; Sugiyama F; Goto K
  • Orexin and melanin-concentrating hormone (MCH) double knockout mice: Compensatory role for MCH in narcolepsy-cataplexy
    Volume: 26 Page(s): A50 - A50
    05/15/2003 Authors: Willie JT; Sinton CM; Mieda M; Maratos-Flier E; Yanagisawa M
  • Pharmacological rescue of narcoleptic orexin-neuron ablated mice
    Volume: 26 Page(s): A288 - A288
    05/15/2003 Authors: Mieda M; Willie JT; Sinton CM; Sakurai T; Yanagisawa M
  • Hypocretin/orexin (H/O) elevates [Ca2+]si s in locus ceruleus (LC) neurons via activation of OXs1s and OXs2s receptors
    Volume: 26 Page(s): A21 - A22
    05/15/2003 Authors: Kohlmeier KA; Chemelli RM; Willie JT; Kisanuki YY; Yanagisawa M; Leonard CS
  • Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal.
    J Neurosci Volume: 23 Page(s): 3106 - 3111
    04/15/2003 Authors: Georgescu D; Zachariou V; Barrot M; Mieda M; Willie JT; Eisch AJ; Yanagisawa M; Nestler EJ; DiLeone RJ
  • Orexin neuron-ablated mice fail to increase vigilance and locomotor activity in response to fasting
    SLEEP Volume: 25 Page(s): A353 - A354
    04/15/2002 Authors: Beuckmann CT; Willie JT; Hara J; Yamanaka A; Sakurai T; Yanagisawa M
  • Orexin (hypocretin) neurons contain dynorphin.
    J Neurosci Volume: 21 Page(s): RC168
    10/01/2001 Authors: Chou TC; Lee CE; Lu J; Elmquist JK; Hara J; Willie JT; Beuckmann CT; Chemelli RM; Sakurai T; Yanagisawa M
  • Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.
    Neuron Volume: 30 Page(s): 345 - 354
    05/01/2001 Authors: Hara J; Beuckmann CT; Nambu T; Willie JT; Chemelli RM; Sinton CM; Sugiyama F; Yagami K; Goto K; Yanagisawa M
  • Genetic ablation of orexin neurons causes narcolepsy in mice
    SLEEP Volume: 24 Page(s): A26 - A27
    04/15/2001 Authors: Beuckmann CT; Hara J; Willie JT; Chemelli RM; Sinton CM; Sakurai T; Yanagisawa M
  • Narcoleptic behavioral arrests in orexin ligand and orexin-2 receptor knockout mice are neurophysiologically distinct
    SLEEP Volume: 24 Page(s): A24 - A24
    04/15/2001 Authors: Willie JT; Sinton CM; Yanagisawa M; Chemelli RM
  • Behavioral characterization of orexin-2 receptor (OX2R) knockout mice
    SLEEP Volume: 24 Page(s): A20 - A21
    04/15/2001 Authors: Tokita S; Chemelli RM; Willie JT; Yanagisawa M
  • To eat or to sleep? Orexin in the regulation of feeding and wakefulness.
    Annu Rev Neurosci Volume: 24 Page(s): 429 - 458
    01/01/2001 Authors: Willie JT; Chemelli RM; Sinton CM; Yanagisawa M
  • Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation.
    Cell Volume: 98 Page(s): 437 - 451
    08/20/1999 Authors: Chemelli RM; Willie JT; Sinton CM; Elmquist JK; Scammell T; Lee C; Richardson JA; Williams SC; Xiong Y; Kisanuki Y
  • Synergistic activation of transcription by physiologically unrelated transcription factors through cooperative DNA-binding.
    Biochem Biophys Res Commun Volume: 247 Page(s): 530 - 535
    06/18/1998 Authors: Vashee S; Willie J; Kodadek T
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