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Profile

Jonathan Sevransky MD,MHS

  • Department of Medicine
    Professor
  • (404) 686-6162
  • jonathan.sevransky@emoryhealthcare.org
Head shot of Jonathan Sevransky

Overview

Dr. Sevransky completed his undergraduate education at Dartmouth College and his medical education and the George Washington University of Medicine. He did his internship and residency at the Presbyterian Hospital of New York (Columbia University) and then a fellowship in Critical Care at the National Institutes of Health and in pulmonary medicine at Johns Hopkins. He joined the faculty at Johns Hopkins in 1999, and served as the director of the MICU at the Johns Hopkins Bayview Medical Center from 1999-2011. While at Johns Hopkins, he completed a masters in clinical investigation at the Johns Hopkins Bloomberg School of Public Health.

Dr. Sevransky was recruited to Emory in 2011, where he currently serves as professor of medicine, the director of the Medical ICU at Emory University Hospital, and as the site director for Emory University Hospital, Emory Critical Care Center. He also serves as the founding director for the Emory Critical Illness Research Center ( E-CIRC), a clinical research collaboration between Emergency Medicine, the Emory Critical Care Center, and the division of Pulmonary, Allergy, Critical Care and Sleep. In 2024 He assumed the Editor in Chief position for the journal, Critical Care Medicine

Jons clinical, educational and research center on the treatment of patients with life-threatening illness. He is a clinical investigator with a primary interest in the treatment of patients with sepsis and complications of sepsis such as acute respiratory distress syndrome (ARDS) and septic shock. An additional focus of investigation is the identification of patient and hospital related factors that may modify treatment effects of novel agents in clinical trials.

Current research projects include studies looking at early markers of sepsis in patients presenting to the emergency room, attempts to improve the treatment patients with sepsis, including potential prehospital markers, a large cohort trial examining the role of ICU organization and structure on in patient mortality, and is working with a team on ways to decrease the cost and efficiency of sepsis clinical trials using novel trial designs while leveraging the electronic medical record.

Dr Sevransky is past chair of the SCCM Discovery Research Network, , and served as an associate editor for the journal Critical Care Medicine. He was also a founding member of the US Critical Illness and Injury Trials Group, He sees patients at Emory University Hospital, and mentors fellows, residents and medical students in clinical investigation in critical care.

Academic Appointment

  • Professor Of Medicine, Medicine, Emory University School of Medicine
  • Eminent Physician, Emory University School of Medicine

Education

Degrees

  • MHS from Johns Hopkins Bloomberg School of Public Health
  • MD from George Washington University
  • BA from Dartmouth College

Research

Focus

  • My first interest relates to complications of sepsis including septic shock and severe sepsis induced acute lung injury. My second interest involves research into patient, treatment, and organizational factors that can modify the effects of interventions in critically ill patients. These factors can range from genetic polymorphisms to intensive care unit staffing and structural components

Publications

  • Peer Review: Present and Future for Critical Care Medicine.
    Crit Care Med Volume: 53 Page(s): e1174 - e1176
    06/01/2025 Authors: Sevransky J; Alexander S; Nazer L; Sarwal A; Szakmany T; Tasker R
  • Higher circulating ACE2 and DPP3 but reduced ACE and angiotensinogen in hyperreninemic sepsis patients.
    Clin Sci (Lond) Volume: 139 Page(s): 43 - 53
    01/15/2025 Authors: Chappell MC; Schaich CL; Busse LW; Clark Files D; Martin GS; Sevransky JE; Hinson JS; Rothman RE; Khanna AK; Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) Investigators
  • Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients.
    Nat Commun Volume: 16 Page(s): 586
    01/10/2025 Authors: Pickering H; Schaenman J; Phan HV; Maguire C; Tsitsiklis A; Rouphael N; Higuita NIA; Atkinson MA; Brakenridge S; Fung M
  • Knowledge Transfer in the 21st Century: The Continuing Evolution of Critical Care Medicine.
    Crit Care Med Volume: 53 Page(s): e1 - e3
    01/01/2025 Authors: Sevransky JE; Barreto EF; Bleck TP; Chen J-T; Dellinger RP; Deutschman CS; Lyons PG; Mariscalo MM; Marshall JC; Maslove DM
  • International multi-cohort analysis identifies novel framework for quantifying immune dysregulation in critical illness: results of the SUBSPACE consortium.
    bioRxiv
    11/15/2024 Authors: Moore AR; Zheng H; Ganesan A; Hasin-Brumshtein Y; Maddali MV; Levitt JE; van der Poll T; Scicluna BP; Giamarellos-Bourboulis EJ; Kotsaki A
  • Stronger association of intact angiotensinogen with mortality than lactate or renin in critical illness: post-hoc analysis from the VICTAS trial.
    Crit Care Volume: 28 Page(s): 333
    10/14/2024 Authors: Chappell MC; Schaich CL; Busse LW; Martin GS; Sevransky JE; Hinson JK; Khanna AK; Vitamin C, Thiamine, Steroids in Sepsis (VICTAS) Investigators
  • COVID-19 Across Pandemic Variant Periods: The Severe Acute Respiratory Infection-Preparedness (SARI-PREP) Study.
    Crit Care Explor Volume: 6 Page(s): e1122
    07/01/2024 Authors: Mukherjee V; Postelnicu R; Parker C; Rivers PS; Anesi GL; Andrews A; Ables E; Morrell ED; Brett-Major DM; Broadhurst MJ
  • Association of Active Renin Content With Mortality in Critically Ill Patients: A Post hoc Analysis of the Vitamin C, Thiamine, and Steroids in Sepsis (VICTAS) Trial.
    Crit Care Med Volume: 52 Page(s): 441 - 451
    03/01/2024 Authors: Busse LW; Schaich CL; Chappell MC; McCurdy MT; Staples EM; Ten Lohuis CC; Hinson JS; Sevransky JE; Rothman RE; Wright DW
  • IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition.
    Nat Commun Volume: 15 Page(s): 404
    01/09/2024 Authors: Haslund-Gourley BS; Woloszczuk K; Hou J; Connors J; Cusimano G; Bell M; Taramangalam B; Fourati S; Mege N; Bernui M
  • Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study.
    Nat Commun Volume: 15 Page(s): 216
    01/03/2024 Authors: Ozonoff A; Jayavelu ND; Liu S; Melamed E; Milliren CE; Qi J; Geng LN; McComsey GA; Cairns CB; Baden LR
  • Is It Time to Reconsider the Concept of "Salvage Therapy" in Refractory Shock?
    Crit Care Med Volume: 51 Page(s): 1821 - 1824
    12/01/2023 Authors: Wieruszewski PM; Sevransky JE; Roberts RJ
  • Relationship of Heterologous Virus Responses and Outcomes in Hospitalized COVID-19 Patients.
    J Immunol Volume: 211 Page(s): 1224 - 1231
    10/15/2023 Authors: Rosenberg-Hasson Y; Holmes TH; Diray-Arce J; Chen J; Kellogg R; Snyder M; Becker PM; Ozonoff A; Rouphael N; Reed EF
  • How Electronic Medical Record Integration Can Support More Efficient Critical Care Clinical Trials.
    Crit Care Clin Volume: 39 Page(s): 733 - 749
    10/01/2023 Authors: Agarwal A; Marion J; Nagy P; Robinson M; Walkey A; Sevransky J
  • Thiamine for Septic Shock: Take Your Vitamins?
    Am J Respir Crit Care Med Volume: 208 Page(s): 513 - 515
    09/01/2023 Authors: Fujii T; Sevransky J
  • Error, Fraud, and Responsibility.
    Crit Care Med Volume: 51 Page(s): 1105 - 1107
    09/01/2023 Authors: Buchman TG; Bleck TP; Busl KM; Dellinger RP; Deutschman CS; Kadri SS; Marshall JC; Maslove DM; Masur H; Osborn TM
  • Xanthine oxidoreductase gene polymorphisms are associated with high risk of sepsis and organ failure.
    Respir Res Volume: 24 Page(s): 177
    07/06/2023 Authors: Gao L; Rafaels N; Dudenkov TM; Damarla M; Damico R; Maloney JP; Moss M; Martin GS; Sevransky J; Shanholtz C
  • Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients.
    Cell Rep Med Volume: 4 Page(s): 101079
    06/20/2023 Authors: Diray-Arce J; Fourati S; Doni Jayavelu N; Patel R; Maguire C; Chang AC; Dandekar R; Qi J; Lee BH; van Zalm P
  • Perceived Hospital Stress, Severe Acute Respiratory Syndrome Coronavirus 2 Activity, and Care Process Temporal Variance During the COVID-19 Pandemic.
    Crit Care Med Volume: 51 Page(s): 445 - 459
    04/01/2023 Authors: Anesi GL; Andrews A; Bai HJ; Bhatraju PK; Brett-Major DM; Broadhurst MJ; Campbell ES; Cobb JP; Gonzalez M; Homami S
  • Association of Vitamin C, Thiamine, and Hydrocortisone Infusion With Long-term Cognitive, Psychological, and Functional Outcomes in Sepsis Survivors: A Secondary Analysis of the Vitamin C, Thiamine, and Steroids in Sepsis Randomized Clinical Trial.
    JAMA Netw Open Volume: 6 Page(s): e230380
    02/01/2023 Authors: Williams Roberson S; Nwosu S; Collar EM; Kiehl AL; Harrison FE; Bastarache J; Wilson JE; Mart MF; Sevransky JE; Ely EW
  • Resuscitation in the First 3 Hours of Sepsis-Induced Hypotension Varies by Patient and Hospital Factors.
    Crit Care Explor Volume: 5 Page(s): e0859
    02/01/2023 Authors: Chen J-T; Roberts RJ; Sevransky JE; Gong MN
  • Under Pressure: Do We "Dare Change Our Way of Caring" for Patients With Shock?
    Crit Care Med Volume: 51 Page(s): 326 - 328
    02/01/2023 Authors: Roberts RJ; Chen J-T; Sevransky JE; Walkey AJ
  • Angiopoietin-Like4 Is a Novel Marker of COVID-19 Severity.
    Crit Care Explor Volume: 5 Page(s): e0827
    01/01/2023 Authors: Bhatraju PK; Morrell ED; Stanaway IB; Sathe NA; Srivastava A; Postelnicu R; Green R; Andrews A; Gonzalez M; Kratochvil CJ
  • Effects of Timing of Invasive Mechanical Ventilation in Patients with Shock. An Analysis of the Multicenter Prospective Observational VOLUME-CHASERS Cohort.
    J Intensive Care Med Volume: 37 Page(s): 1435 - 1441
    11/01/2022 Authors: Goel NN; Chen J-T; Roberts R; Sevransky J; Gong MN; Mathews KS; VOLUME-CHASERS Study Group and Society of Critical Care Medicine Discovery Network
  • Biological Effects of Intravenous Vitamin C on Neutrophil Extracellular Traps and the Endothelial Glycocalyx in Patients with Sepsis-Induced ARDS.
    Nutrients Volume: 14
    10/21/2022 Authors: Qiao X; Kashiouris MG; L'Heureux M; Fisher BJ; Leichtle SW; Truwit JD; Nanchal R; Hite RD; Morris PE; Martin GS
  • Severe Acute Respiratory Infection-Preparedness: Protocol for a Multicenter Prospective Cohort Study of Viral Respiratory Infections.
    Crit Care Explor Volume: 4 Page(s): e0773
    10/01/2022 Authors: Postelnicu R; Srivastava A; Bhatraju PK; Wurfelc MM; Anesi GL; Gonzalez M; Andrews A; Lutrick K; Kumar VK; Uyeki TM
  • SWEAT ICU-An Observational Study of Physician Workload and the Association of Physician Outcomes in Academic ICUs.
    Crit Care Explor Volume: 4 Page(s): e0774
    10/01/2022 Authors: Agarwal A; Chen J-T; Coopersmith CM; Denson JL; Dickert NW; Ferrante LE; Gershengorn HB; Gosine AD; Hayward BJ; Kaur N
  • Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study.
    EBioMedicine Volume: 83 Page(s): 104208
    09/01/2022 Authors: Ozonoff A; Schaenman J; Jayavelu ND; Milliren CE; Calfee CS; Cairns CB; Kraft M; Baden LR; Shaw AC; Krammer F
  • Is "Set It and Forget It" Bad Medicine for Sedation and Analgesia for Intubated Emergency Department Patients?
    Crit Care Med Volume: 50 Page(s): 1283 - 1285
    08/01/2022 Authors: Winkle J; Sevransky J
  • Implementation of an EMS protocol to improve prehospital sepsis recognition.
    Am J Emerg Med Volume: 57 Page(s): 34 - 38
    07/01/2022 Authors: Polito CC; Bloom I; Dunn C; Moore R; Chen J; Yancey AH; Sevransky JE
  • Redefining critical illness.
    Nat Med Volume: 28 Page(s): 1141 - 1148
    06/01/2022 Authors: Maslove DM; Tang B; Shankar-Hari M; Lawler PR; Angus DC; Baillie JK; Baron RM; Bauer M; Buchman TG; Calfee CS
  • The authors reply.
    Crit Care Med Volume: 50 Page(s): e604 - e606
    06/01/2022 Authors: Bleck TP; Buchman TG; Chang CWJ; Dellinger RP; Deutschman CS; Kadri SS; Marshall JC; Maslove DM; Masur H; Osborn TM
  • Phase 2 Vitamin C Sepsis Trials: Another Brick in the (Evidence) Wall?
    Crit Care Med Volume: 50 Page(s): 897 - 899
    05/01/2022 Authors: Agarwal A; Oczkowski S; Sevransky J
  • The Future of Critical Care: Optimizing Technologies and a Learning Healthcare System to Potentiate a More Humanistic Approach to Critical Care.
    Crit Care Explor Volume: 4 Page(s): e0659
    03/01/2022 Authors: Meissen H; Gong MN; Wong A-KI; Zimmerman JJ; Nadkarni N; Kane-Gil SL; Amador-Castaneda J; Bailey H; Brown SM; DePriest AD
  • SWEAT-ICU: A STUDY OF WORKLOAD AND THE ASSOCIATION OF OUTCOMES IN THE ICU
    Volume: 50 Page(s): 156 - 156
    01/01/2022 Authors: Agarwal A; Barnes T; Chen T; Denson J; Desai K; Ferrante L; Gershengorn H; Gosine A; Hayward B; Kaur N
  • SEVERE ACUTE RESPIRATORY INFECTION - PREPAREDNESS (SARI-PREP): A MULTICENTER PROSPECTIVE STUDY
    Volume: 50 Page(s): 253 - 253
    01/01/2022 Authors: Bhatraju P; Srivastava A; Anesi G; Postelnicu R; Andrews A; Gonzalez M; Kratochvil C; Kumar V; Wyles D; Lee R
  • HOSPITAL STRESS AND CARE PROCESS TEMPORAL VARIANCE DURING THE COVID-19 PANDEMIC IN THE US
    Volume: 50 Page(s): 42 - 42
    01/01/2022 Authors: Anesi G; Srivastava A; Bai J; Andrews A; Bhatraju P; Gonzalez M; Kratochvil C; Kumar V; Landsittel D; Liebler J
  • 21st Century Evidence: Randomized Controlled Trials Versus Systematic Reviews and Meta-Analyses.
    Crit Care Med Volume: 49 Page(s): 2001 - 2002
    12/01/2021 Authors: Agarwal A; Rochwerg B; Sevransky JE
  • Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.
    Intensive Care Med Volume: 47 Page(s): 1181 - 1247
    11/01/2021 Authors: Evans L; Rhodes A; Alhazzani W; Antonelli M; Coopersmith CM; French C; Machado FR; Mcintyre L; Ostermann M; Prescott HC
  • Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021.
    Crit Care Med Volume: 49 Page(s): e1063 - e1143
    11/01/2021 Authors: Evans L; Rhodes A; Alhazzani W; Antonelli M; Coopersmith CM; French C; Machado FR; Mcintyre L; Ostermann M; Prescott HC
  • Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021.
    Crit Care Med Volume: 49 Page(s): 1974 - 1982
    11/01/2021 Authors: Evans L; Rhodes A; Alhazzani W; Antonelli M; Coopersmith CM; French C; Machado FR; Mcintyre L; Ostermann M; Prescott HC
  • Immune thrombocytopenia in 2 healthy young women after the Pfizer-BioNTech BNT16B2b2 messenger RNA coronavirus disease 2019 vaccination.
    J Am Coll Emerg Physicians Open Volume: 2 Page(s): e12531
    10/01/2021 Authors: Collins EC; Carr MJ; Kim JS; Lewis J; Maleque N; Desai K; Chen L; Sevransky J; Gaddh M; Rouphael N
  • Any Role of High-Dose Vitamin C for Septic Shock in 2021?
    Semin Respir Crit Care Med Volume: 42 Page(s): 672 - 682
    10/01/2021 Authors: Agarwal A; Hager DN; Sevransky JE
  • A Rare Case of Cerebral Malaria with Neurologic Recovery
    Volume: 203
    05/01/2021 Authors: Desai K; Agarwal A; Sevransky JE
  • Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial.
    JAMA Volume: 325 Page(s): 742 - 750
    02/23/2021 Authors: Sevransky JE; Rothman RE; Hager DN; Bernard GR; Brown SM; Buchman TG; Busse LW; Coopersmith CM; DeWilde C; Ely EW
  • Standardized Care Is Better Than Individualized Care for the Majority of Critically Ill Patients.
    Crit Care Med Volume: 49 Page(s): 151 - 155
    01/01/2021 Authors: Sevransky JE; Agarwal A; Jabaley CS; Rochwerg B
  • Evaluation of Vasopressor Exposure and Mortality in Patients With Septic Shock.
    Crit Care Med Volume: 48 Page(s): 1445 - 1453
    10/01/2020 Authors: Roberts RJ; Miano TA; Hammond DA; Patel GP; Chen J-T; Phillips KM; Lopez N; Kashani K; Qadir N; Cairns CB
  • Variation in Fluid and Vasopressor Use in Shock With and Without Physiologic Assessment: A Multicenter Observational Study.
    Crit Care Med Volume: 48 Page(s): 1436 - 1444
    10/01/2020 Authors: Chen J-T; Roberts R; Fazzari MJ; Kashani K; Qadir N; Cairns CB; Mathews K; Park P; Khan A; Gilmore JF
  • Pandemic-Related Submissions: The Challenge of Discerning Signal Amidst Noise.
    Crit Care Med Volume: 48 Page(s): 1099 - 1102
    08/01/2020 Authors: Bleck TP; Buchman TG; Dellinger RP; Deutschman CS; Marshall JC; Maslove DM; Masur H; Parker MM; Prough DS; Sarwal A
  • Pandemic-Related Submissions: The Challenge of Discerning Signal Amidst Noise.
    Crit Care Med
    06/11/2020 Authors: Kaplan LJ; Bleck TP; Buchman TG; Dellinger RP; Deutschman CS; Marshall JC; Maslove DM; Masur H; Parker MM; Prough DS
  • In response: Letter on update to the Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) protocol.
    Trials Volume: 21 Page(s): 351
    04/22/2020 Authors: Lindsell CJ; McGlothlin A; Nwosu S; Rice TW; Hall A; Bernard GR; Busse LW; Ely EW; Fowler AA; Gaieski DF
  • Misinformation During the Coronavirus Disease 2019 Outbreak: How Knowledge Emerges From Noise.
    Crit Care Explor Volume: 2 Page(s): e0098
    04/01/2020 Authors: Rochwerg B; Parke R; Murthy S; Fernando SM; Leigh JP; Marshall J; Adhikari NKJ; Fiest K; Fowler R; Lamontagne F
  • Update to the Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) protocol: statistical analysis plan for a prospective, multicenter, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial.
    Trials Volume: 20 Page(s): 670
    12/04/2019 Authors: Lindsell CJ; McGlothlin A; Nwosu S; Rice TW; Hall A; Bernard GR; Busse LW; Ely EW; Fowler AA; Gaieski DF
  • Structural features shared by ICUs belonging to research networks an international survey. "Critical care research network survey"
    JOURNAL OF CRITICAL CARE Volume: 54 Page(s): 99 - 104
    12/01/2019 Authors: Nguyen Y-L; Hejblum G; Guidet B; Capuzzo M; Rowan K; Flaaten H; Valentin A; Kahn JM; Ferrer R; Rhodes A
  • Toward Increased Understanding of the Steroid Controversy in Septic Shock.
    Crit Care Med Volume: 47 Page(s): 1677 - 1679
    12/01/2019 Authors: Russell JA; Sevransky J
  • Association between hospital mortality and inspiratory airway pressures in mechanically ventilated patients without acute respiratory distress syndrome: a prospective cohort study.
    Crit Care Volume: 23 Page(s): 367
    11/21/2019 Authors: Sahetya SK; Mallow C; Sevransky JE; Martin GS; Girard TD; Brower RG; Checkley W; Society of Critical Care Medicine Discovery Network Critical Illness Outcomes Study Investigators
  • A CASE OF IMMUNE RECONSTITUTION SYNDROME IN DISSEMINATED HISTOPLASMOSIS
    Volume: 156 Page(s): 570A - 570A
    10/01/2019 Authors: Agarwal A; Armstrong W; Sevransky J
  • Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial.
    JAMA Volume: 322 Page(s): 1261 - 1270
    10/01/2019 Authors: Fowler AA; Truwit JD; Hite RD; Morris PE; DeWilde C; Priday A; Fisher B; Thacker LR; Natarajan R; Brophy DF
  • Typologies of Decision-Makers in the ICU: A Qualitative Study of Patients With Acute Respiratory Distress Syndrome and Sepsis and Their Surrogates.
    Crit Care Explor Volume: 1 Page(s): e0011
    05/01/2019 Authors: Lava MS; Dickert NW; Frew PM; Martin GS; Sevransky JE
  • The authors reply.
    Crit Care Med Volume: 47 Page(s): e429
    05/01/2019 Authors: Tisherman SA; Spevetz A; Blosser SA; Brown D; Chang C; Efron PA; O'Connor M; Sevransky JE; Wessman BT
  • The Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) Protocol: a prospective, multi-center, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial.
    Trials Volume: 20 Page(s): 197
    04/05/2019 Authors: Hager DN; Hooper MH; Bernard GR; Busse LW; Ely EW; Fowler AA; Gaieski DF; Hall A; Hinson JS; Jackson JC
  • Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome-More Research Is Needed.
    Crit Care Med Volume: 47 Page(s): 118 - 120
    01/01/2019 Authors: Rochwerg B; Alhazzani W; Sevransky JE
  • Front Line of Sepsis Care: Training Emergency Medical Services Providers to Identify Sepsis Using a Validated Sepsis Screening Tool
    Volume: 199
    01/01/2019 Authors: Sayad K; Rajasekar S; Mohsin A; Nabavi N; Yancey A; Sevransky JE; Polito C
  • VOLUME-CHASER: A Multicenter Observational Study Evaluating the Association Between Vasopressor Exposure and Mortality in Patients with Septic Shock
    Volume: 199
    01/01/2019 Authors: Roberts R; Chen J; Miano TA; Patel GP; Hammond DA; Phillips KM; Lopez ND; Gong MN; Sevransky JE; Lat I
  • VOLUME-CHASER: Compliance with Surviving Sepsis Campaign and Mortality Varies with Hospital in Patients with Septic Shock
    Volume: 199
    01/01/2019 Authors: Chen J; Roberts RJ; Sevransky J; Gong MN
  • Volume-Chaser: Use of Critical Care Ultrasound and Physiologic Parameter Assessments for Fluid Resuscitation Is Not Associated with Survival in Patients with Shock
    Volume: 199
    01/01/2019 Authors: Chen J; Roberts RJ; Sevransky J; Gong MN
  • Volume-Chaser: A Multicenter Observational Study of Fluid Resuscitation in Septic and Non-Septic Shock
    Volume: 199
    01/01/2019 Authors: Chen J; Roberts RJ; Sevransky J; Gong MN
  • Association Between Driving Pressure and Mortality in Non-ARDS Patients
    Volume: 199
    01/01/2019 Authors: Sahetya S; Mallow C; Sevransky JE; Martin GS; Girard K; Girard TD; Checkley W
  • A Case for Change in Adult Critical Care Training for Physicians in the United States: A White Paper Developed by the Critical Care as a Specialty Task Force of the Society of Critical Care Medicine.
    Crit Care Med Volume: 46 Page(s): 1577 - 1584
    10/01/2018 Authors: Tisherman SA; Spevetz A; Blosser SA; Brown D; Chang C; Efron PA; O'Connor M; Sevransky JE; Wessman BT
  • Editor's Choice-The cardiovascular implications of sedatives in the cardiac intensive care unit.
    Eur Heart J Acute Cardiovasc Care Volume: 7 Page(s): 671 - 683
    10/01/2018 Authors: Zakaria S; Kwong HJ; Sevransky JE; Williams MS; Chandra-Strobos N
  • Corticosteroids in Sepsis: An Updated Systematic Review and Meta-Analysis.
    Crit Care Med Volume: 46 Page(s): 1411 - 1420
    09/01/2018 Authors: Rochwerg B; Oczkowski SJ; Siemieniuk RAC; Agoritsas T; Belley-Cote E; D'Aragon F; Duan E; English S; Gossack-Keenan K; Alghuroba M
  • Glucometry When Using Vitamin C in Sepsis: A Note of Caution.
    Chest Volume: 154 Page(s): 228 - 229
    07/01/2018 Authors: Hager DN; Martin GS; Sevransky JE; Hooper MH
  • Pharmacogenomic biomarkers do not predict response to drotrecogin alfa in patients with severe sepsis.
    Ann Intensive Care Volume: 8 Page(s): 16
    01/31/2018 Authors: Annane D; Mira J-P; Ware LB; Gordon AC; Hinds CJ; Christiani DC; Sevransky J; Barnes K; Buchman TG; Heagerty PJ
  • A Quality Improvement Study to Increase Sepsis Recognition by EMS Providers Using the Prehospital Sepsis (PRESS) Screening Tool
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 197
    01/01/2018 Authors: Polito C; Rajasekar S; Nabavi N; Mohsin A; Martin GS; Yancey A; Sevransky JE
  • Classification and Regression Tree Analysis to Predict Mortality in EMS Patients at Risk for Sepsis
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 197
    01/01/2018 Authors: Law S; Rajasekar S; Dunn C; Bloom I; Patel A; Warnock M; Cotsonis G; Martin G; Sevransky J; Polito C
  • Do SOFA, qSOFA, and SIRS Predict In-Hospital Mortality in Septic Patients Admitted from the Emergency Department to the Intensive Care Unit in an Urban, Safety Net Hospital?
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 197
    01/01/2018 Authors: Graziani C; Mohsin A; Wu H; Feng H; Sevransky JE; Esper AM; Martin GS; Polito CC
  • Early risk factors and the role of fluid administration in developing acute respiratory distress syndrome in septic patients.
    Ann Intensive Care Volume: 7 Page(s): 11
    12/01/2017 Authors: Seethala RR; Hou PC; Aisiku IP; Frendl G; Park PK; Mikkelsen ME; Chang SY; Gajic O; Sevransky J
  • A Survey of Corticosteroid Dosing for Exacerbations of Chronic Obstructive Pulmonary Disease Requiring Assisted Ventilation.
    Chronic Obstr Pulm Dis Volume: 4 Page(s): 186 - 193
    07/15/2017 Authors: Kiser TH; Sevransky JE; Krishnan JA; Tonascia J; Wise RA; Checkley W; Walsh J; Sullivan JB; Wilson KC; Barker A
  • Corticosteroids in sepsis: an updated systematic review and meta-analysis (protocol).
    BMJ Open Volume: 7 Page(s): e016847
    06/30/2017 Authors: Rochwerg B; Oczkowski S; Siemieniuk RA; Menon K; Szczeklik W; English S; Agoritsas T; Belley-Cote E; D'Aragon F; Alhazzani W
  • Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study.
    Lancet Respir Med Volume: 5 Page(s): 500 - 511
    06/01/2017 Authors: Beigel JH; Tebas P; Elie-Turenne M-C; Bajwa E; Bell TE; Cairns CB; Shoham S; Deville JG; Feucht E; Feinberg J
  • Stick to What You Know: Do Visiting Intensivists Worsen Outcomes?
    Crit Care Med Volume: 45 Page(s): 1095 - 1096
    06/01/2017 Authors: Checkley W; Sevransky J
  • Patient- and Family-Centered Care: First Steps on a Long Journey.
    Crit Care Med Volume: 45 Page(s): 757 - 758
    05/01/2017 Authors: Sevransky JE; Nicholl B; Nicholl J-B; Buchman TG
  • Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.
    Crit Care Med Volume: 45 Page(s): 486 - 552
    03/01/2017 Authors: Rhodes A; Evans LE; Alhazzani W; Levy MM; Antonelli M; Ferrer R; Kumar A; Sevransky JE; Sprung CL; Nunnally ME
  • Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.
    Intensive Care Med Volume: 43 Page(s): 304 - 377
    03/01/2017 Authors: Rhodes A; Evans LE; Alhazzani W; Levy MM; Antonelli M; Ferrer R; Kumar A; Sevransky JE; Sprung CL; Nunnally ME
  • Prehospital sepsis care: Understanding provider knowledge, behaviors, and attitudes.
    Am J Emerg Med Volume: 35 Page(s): 362 - 365
    02/01/2017 Authors: Polito CC; Bloom I; Yancey AH; Lairet JR; Isakov AP; Martin GS; Rajasekar S; Patel A; Murphy DJ; Sevransky JE
  • Evaluation of RBC Transfusion Practice in Adult ICUs and the Effect of Restrictive Transfusion Protocols on Routine Care.
    Crit Care Med Volume: 45 Page(s): 271 - 281
    02/01/2017 Authors: Seitz KP; Sevransky JE; Martin GS; Roback JD; Murphy DJ
  • PREVALENCE AND OUTCOMES OF HYPEROXIA IN THE INTENSIVE CARE UNIT
    Volume: 44
    12/01/2016 Authors: Shaefi S; Mueller A; -Goodspeed VB; Shahul S; Sarge T; Sevransky J; Talmor D
  • 937: PREVALENCE AND OUTCOMES OF HYPEROXIA IN THE INTENSIVE CARE UNIT.
    Crit Care Med Volume: 44 Page(s): 310
    12/01/2016 Authors: Shaefi S; Mueller A; Banner-Goodspeed V; Shahul S; Sarge T; Sevransky J; Talmor D
  • Dynamic Measures to Determine Volume Responsiveness: Logical, Biologically Plausible, and Unproven.
    Crit Care Med Volume: 44 Page(s): 1923 - 1926
    10/01/2016 Authors: Sevransky JE
  • The authors reply.
    Crit Care Med Volume: 44 Page(s): e447 - e448
    06/01/2016 Authors: Sueblinvong V; Johnson DW; Weinstein GL; Connor MJ; Crozier I; Liddell AM; Franch HA; Wall BR; Kalil AC; Feldman M
  • Survey of Annual Staffing Workloads for Adult Critical Care Physicians Working in the United States.
    Ann Am Thorac Soc Volume: 13 Page(s): 751 - 753
    05/01/2016 Authors: Sevransky JE; Chai ZJ; Cotsonis GA; Cobb JP; Pastores SM
  • Ethical and regulatory challenges in advancing prehospital research: focus on sepsis.
    Am J Emerg Med Volume: 34 Page(s): 623 - 625
    03/01/2016 Authors: Polito CC; Sevransky JE; Dickert NW
  • High-Dose Versus Low-Dose Systemic Steroids in the Treatment of Acute Exacerbations of Chronic Obstructive Pulmonary Disease: Systematic Review.
    Chronic Obstr Pulm Dis Volume: 3 Page(s): 580 - 588
    02/17/2016 Authors: Bonilla Arcos D; Krishnan JA; Vandivier RW; Sevransky JE; Checkley W; Kiser TH; Sullivan JL; Walsh JW; Wise RA; Wilson KC
  • Excellence in Critical Care Units.
    Crit Care Med Volume: 44 Page(s): 1 - 2
    01/01/2016 Authors: Sevransky JE; Fessler HE
  • Using Incentives to Improve Resource Utilization: A Quasi-Experimental Evaluation of an ICU Quality Improvement Program.
    Crit Care Med Volume: 44 Page(s): 162 - 170
    01/01/2016 Authors: Murphy DJ; Lyu PF; Gregg SR; Martin GS; Hockenberry JM; Coopersmith CM; Sterling M; Buchman TG; Sevransky J
  • Utility Of Pre-Hospital Glasgow Coma Scale In Predicting In-Hospital Mortality In Patients With Sepsis
    Volume: 193
    01/01/2016 Authors: Dolan R; Polito C; Isakov A; Yancey A; Bloom I; Martin GS; Sevransky JE
  • End-Inspiratory Airway Pressures And Patient-Centered Outcomes In The Critical Illness Outcomes Study
    Volume: 193
    01/01/2016 Authors: Mallow CM; Sevransky JE; Martin GS; Girard TD; Brower RG; Checkley W
  • Deciding Factors For Admission: Intensive Care Versus Intermediate Care
    Volume: 193
    01/01/2016 Authors: Talbot JT; Isakov A; Yancey A; Bloom I; Martin GS; Sevransky JE; Polito C
  • Improving Prehospital Recognition Of Severe Sepsis (press): Knowledge And Attitudes Of first Responders
    Volume: 193
    01/01/2016 Authors: Polito C; Bloom I; Yancey A; Lairet J; Isakov A; Murphy D; Martin GS; Sevransky JE
  • 1318: WHAT IS AN INTENSIVIST FTE? A DESCRIPTIVE ANALYSIS OF ICU ATTENDING PHYSICIAN STAFFING AND SERVICE.
    Crit Care Med Volume: 43 Page(s): 331
    12/01/2015 Authors: Chai ZJ; Pastores S; Cobb JP; Cotsonis G; Sevransky J
  • 768: EFFECT OF AN AUDIT AND FEEDBACK PROCESS ON PAIN, AGITATION, AND DELIRIUM DOCUMENTATION IN 15 ICUS.
    Crit Care Med Volume: 43 Page(s): 193
    12/01/2015 Authors: Murphy D; Overton E; Folse S; Holder C; McMurtry J; Zellinger M; Sevransky J
  • 303: OUTCOMES OF CRITICALLY ILL PATIENTS WITH ALCOHOL ABUSE: RESULTS FROM THE USCIITG-CIOS.
    Crit Care Med Volume: 43 Page(s): 77
    12/01/2015 Authors: Hirsch N; Sevransky J; Checkley W; Martin G
  • RESTRICTIVE TRANSFUSION PROTOCOLS IN CRITICAL CARE: DO THEY AFFECT TRANSFUSION PRACTICE?
    Volume: 43
    12/01/2015 Authors: Seitz K; Sevransky J; Martin G; Roback J; Murphy D
  • OUTCOMES OF CRITICALLY ILL PATIENTS WITH ALCOHOL ABUSE: RESULTS FROM THE USCIITG-CIOS
    Volume: 43
    12/01/2015 Authors: Hirsch N; Sevransky J; Checkley W; Martin G
  • WHAT IS AN INTENSIVIST FTE? A DESCRIPTIVE ANALYSIS OF ICU ATTENDING PHYSICIAN STAFFING AND SERVICE
    Volume: 43
    12/01/2015 Authors: Chai ZJ; Pastores S; Cobb JP; Cotsonis G; Sevransky J
  • EFFECT OF AN AUDIT AND FEEDBACK PROCESS ON PAIN, AGITATION, AND DELIRIUM DOCUMENTATION IN 15 ICUS
    Volume: 43
    12/01/2015 Authors: Murphy D; Overton E; Folse S; Holder C; McMurtry J; Zellinger M; Sevransky J
  • 772: RESTRICTIVE TRANSFUSION PROTOCOLS IN CRITICAL CARE: DO THEY AFFECT TRANSFUSION PRACTICE?
    Crit Care Med Volume: 43 Page(s): 194
    12/01/2015 Authors: Seitz K; Sevransky J; Martin G; Roback J; Murphy D
  • Development of a Core Clinical Dataset to Characterize Serious Illness, Injuries, and Resource Requirements for Acute Medical Responses to Public Health Emergencies.
    Crit Care Med Volume: 43 Page(s): 2403 - 2408
    11/01/2015 Authors: Murphy DJ; Rubinson L; Blum J; Isakov A; Bhagwanjee S; Cairns CB; Cobb JP; Sevransky JE; United States Critical Illness and Injury Trials GroupProgram for Emergency Preparedness
  • Protocols and Hospital Mortality in Critically Ill Patients: The United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study.
    Crit Care Med Volume: 43 Page(s): 2076 - 2084
    10/01/2015 Authors: Sevransky JE; Checkley W; Herrera P; Pickering BW; Barr J; Brown SM; Chang SY; Chong D; Kaufman D; Fremont RD
  • Critical Care for Multiple Organ Failure Secondary to Ebola Virus Disease in the United States.
    Crit Care Med Volume: 43 Page(s): 2066 - 2075
    10/01/2015 Authors: Sueblinvong V; Johnson DW; Weinstein GL; Connor MJ; Crozier I; Liddell AM; Franch HA; Wall BR; Kalil AC; Feldman M
  • Restrictive Transfusion Protocols in Critical Care: Structural ICU Factors and Inappropriate Transfusions
    Volume: 55 Page(s): 176A - 177A
    09/01/2015 Authors: Seitz K; Sevransky J; Roback JD; Murphy DJ
  • Prehospital recognition of severe sepsis: development and validation of a novel EMS screening tool.
    Am J Emerg Med Volume: 33 Page(s): 1119 - 1125
    09/01/2015 Authors: Polito CC; Isakov A; Yancey AH; Wilson DK; Anderson BA; Bloom I; Martin GS; Sevransky JE
  • The Use of TKM-100802 and Convalescent Plasma in 2 Patients With Ebola Virus Disease in the United States.
    Clin Infect Dis Volume: 61 Page(s): 496 - 502
    08/15/2015 Authors: Kraft CS; Hewlett AL; Koepsell S; Winkler AM; Kratochvil CJ; Larson L; Varkey JB; Mehta AK; Lyon GM; Friedman-Moraco RJ
  • Known Unknowns.
    Crit Care Med Volume: 43 Page(s): 1557 - 1558
    08/01/2015 Authors: Sevransky JE
  • Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome*.
    Crit Care Med Volume: 43 Page(s): 288 - 295
    02/01/2015 Authors: Grissom CK; Hirshberg EL; Dickerson JB; Brown SM; Lanspa MJ; Liu KD; Schoenfeld D; Tidswell M; Hite RD; Rock P
  • Timing of low tidal volume ventilation and intensive care unit mortality in acute respiratory distress syndrome. A prospective cohort study.
    Am J Respir Crit Care Med Volume: 191 Page(s): 177 - 185
    01/15/2015 Authors: Needham DM; Yang T; Dinglas VD; Mendez-Tellez PA; Shanholtz C; Sevransky JE; Brower RG; Pronovost PJ; Colantuoni E
  • Factors associated with medication warning acceptance for hospitalized adults.
    J Hosp Med Volume: 10 Page(s): 19 - 25
    01/01/2015 Authors: Knight AM; Falade O; Maygers J; Sevransky JE
  • Corticosteroid Dosing For Acute Exacerbations Of Chronic Obstructive Pulmonary Disease Requiring Ventilatory Support
    Volume: 191
    01/01/2015 Authors: Kiser TH; Sevransky JE; Krishnan JA; Tonascia J; Wise RA; Checkley W; Walsh JW; Sullivan J; Wilson KC; Moss M
  • Predictors Of Early Antibiotic Administration In Patients Suspected Of Sepsis
    Volume: 191
    01/01/2015 Authors: Husain AA; Ahmed AO; Amin OI; Berger M; Tomazic-Allen S; Brown M; Sevransky JE; Martin GS
  • Body temperature and mortality in patients with acute respiratory distress syndrome.
    Am J Crit Care Volume: 24 Page(s): 15 - 23
    01/01/2015 Authors: Schell-Chaple HM; Puntillo KA; Matthay MA; Liu KD; National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network
  • Preparing for critical care services to patients with Ebola.
    Ann Intern Med Volume: 161 Page(s): 831 - 832
    12/02/2014 Authors: Decker BK; Sevransky JE; Barrett K; Davey RT; Chertow DS
  • DETECTION OF SEVERE SEPSIS IN THE PRE-HOSPITAL SETTING: HOW ARE WE DOING?
    CRITICAL CARE MEDICINE Volume: 42
    12/01/2014 Authors: Polito C; Isakov A; Yancey A; Martin G; Wilson D; Anderson B; Bloom I; Sevransky J
  • PRE-HOSPITAL IDENTIFICATION OF PATIENTS WITH SEVERE SEPSIS: DEVELOPMENT OF A NOVEL PREDICTION SCORE
    CRITICAL CARE MEDICINE Volume: 42
    12/01/2014 Authors: Polito C; Isakov A; Yancey A; Martin G; Wilson D; Anderson B; Bloom I; Sevransky J
  • APRN-LED PRIMARY PALLIATIVE CARE IN THE MEDICAL ICU
    CRITICAL CARE MEDICINE Volume: 42
    12/01/2014 Authors: Holder C; Clevenger C; Sevransky J
  • Patient factors associated with identification of sepsis in the ED.
    Am J Emerg Med Volume: 32 Page(s): 1280 - 1281
    10/01/2014 Authors: Wilson DK; Polito CC; Haber MJ; Yancey A; Martin GS; Isakov A; Anderson BJ; Kundel V; Sevransky JE
  • Global burden of influenza as a cause of cardiopulmonary morbidity and mortality.
    Glob Heart Volume: 9 Page(s): 325 - 336
    09/01/2014 Authors: Fischer WA; Gong M; Bhagwanjee S; Sevransky J
  • Navigating the institutional review board approval process in a multicenter observational critical care study.
    Crit Care Med Volume: 42 Page(s): 1105 - 1109
    05/01/2014 Authors: Polito CC; Cribbs SK; Martin GS; O'Keeffe T; Herr D; Rice TW; Sevransky JE
  • Physical complications in acute lung injury survivors: a two-year longitudinal prospective study.
    Crit Care Med Volume: 42 Page(s): 849 - 859
    04/01/2014 Authors: Fan E; Dowdy DW; Colantuoni E; Mendez-Tellez PA; Sevransky JE; Shanholtz C; Himmelfarb CRD; Desai SV; Ciesla N; Herridge MS
  • Structure, process, and annual ICU mortality across 69 centers: United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study.
    Crit Care Med Volume: 42 Page(s): 344 - 356
    02/01/2014 Authors: Checkley W; Martin GS; Brown SM; Chang SY; Dabbagh O; Fremont RD; Girard TD; Rice TW; Howell MD; Johnson SB
  • Assessing Sepsis Survivor And Family Knowledge And Attitudes Regarding Sepsis Outcomes
    Volume: 189
    01/01/2014 Authors: Kundel V; Martin G; O'Brien J; Dickert N; Sevransky J
  • Patient Factors Associated With Emergency Department Sepsis Diagnosis By Clinicians
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 189
    01/01/2014 Authors: Wilson DK; Polito C; Anderson B; Haber MJ; Kundel V; Martin GS; Isakov A; Yancey A; Sevransky JE
  • Association Between Clinical Protocols And Hospital Mortality In Critically Ill Patients: United States Critical Illness And Injury Trials Group-Critical Illness Outcomes Study (usciitg-Cios)
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 189
    01/01/2014 Authors: Sevransky JE; Checkley W; Morris PE; Pickering BW; Hoag JB; Shahul S; Kerlin MP; Putman M; Patil N; Guzman J
  • Use of Antipsychotics for the Prevention of Icu Delirium
    Volume: 41
    12/01/2013 Authors: Hawkins A; Sevransky J; Folse S
  • Hot or Not: Does EMS Tactile Temperature Correlate with Core Temperature and Risk of Sepsis?
    CRITICAL CARE MEDICINE Volume: 41
    12/01/2013 Authors: Anderson B; Polito C; Wilson D; Kundel V; Donnelly C; Yancey A; Isakov A; Sevransky J
  • More, please.
    Crit Care Med Volume: 41 Page(s): 2828 - 2829
    12/01/2013 Authors: Sevransky JE; Shorr A
  • Factors associated with timing of initiation of physical therapy in patients with acute lung injury.
    J Crit Care Volume: 28 Page(s): 980 - 984
    12/01/2013 Authors: Mendez-Tellez PA; Dinglas VD; Colantuoni E; Ciesla N; Sevransky JE; Shanholtz C; Pronovost PJ; Needham DM
  • Process of Care Elements Associated With the Failure to Provide Lung Protective Ventilation for Patients With ARDS
    CHEST Volume: 144
    10/01/2013 Authors: Ahmed H; Husain A; Martin G; Sevransky J; Murphy D
  • Contemporary ventilator management in patients with and at risk of ALI/ARDS.
    Respir Care Volume: 58 Page(s): 578 - 588
    04/01/2013 Authors: Chang SY; Dabbagh O; Gajic O; Patrawalla A; Elie M-C; Talmor DS; Malhotra A; Adesanya A; Anderson HL; Blum JM
  • Neuromuscular blocking agents in acute respiratory distress syndrome: a systematic review and meta-analysis of randomized controlled trials.
    Crit Care Volume: 17 Page(s): R43
    03/11/2013 Authors: Alhazzani W; Alshahrani M; Jaeschke R; Forel JM; Papazian L; Sevransky J; Meade MO
  • Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012.
    Intensive Care Med Volume: 39 Page(s): 165 - 228
    02/01/2013 Authors: Dellinger RP; Levy MM; Rhodes A; Annane D; Gerlach H; Opal SM; Sevransky JE; Sprung CL; Douglas IS; Jaeschke R
  • Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012.
    Crit Care Med Volume: 41 Page(s): 580 - 637
    02/01/2013 Authors: Dellinger RP; Levy MM; Rhodes A; Annane D; Gerlach H; Opal SM; Sevransky JE; Sprung CL; Douglas IS; Jaeschke R
  • ROAD BLOCKS TO INSTITUTIONAL REVIEW BOARD APPROVAL OF A MULTICENTER OBSERVATIONAL CRITICAL CARE STUDY
    CRITICAL CARE MEDICINE Volume: 40 Page(s): U18 - U18
    12/01/2012 Authors: Polito C; Cribbs S; Martin G; O'Keeffe T; Herr D; Rice T; Sevransky J
  • Does sepsis treatment differ between primary and overflow intensive care units?
    J Hosp Med Volume: 7 Page(s): 600 - 605
    10/01/2012 Authors: Vishnupriya K; Falade O; Workneh A; Chandolu S; Landis R; Elizabeth K; Iyengar R; Wright S; Sevransky J
  • Prehospital amiodarone may increase the incidence of acute respiratory distress syndrome among patients at risk.
    J Crit Care Volume: 27 Page(s): 447 - 453
    10/01/2012 Authors: Karnatovskaia LV; Festic E; Gajic O; Carter RE; Lee AS; US Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG-LIPS)
  • Design, conduct, and analysis of a multicenter, pharmacogenomic, biomarker study in matched patients with severe sepsis treated with or without drotrecogin Alfa (activated).
    Ann Intensive Care Volume: 2 Page(s): 15
    06/13/2012 Authors: Annane D; Mira JP; Ware LB; Gordon AC; Sevransky J; Stber F; Heagerty PJ; Wellman HF; Neira M; Mancini AD
  • A rose is a rose is a rose?
    Crit Care Med Volume: 40 Page(s): 1998 - 1999
    06/01/2012 Authors: Sevransky JE; Ward NS; Dellinger RP
  • Lung protective mechanical ventilation and two year survival in patients with acute lung injury: prospective cohort study.
    BMJ Volume: 344 Page(s): e2124
    04/05/2012 Authors: Needham DM; Colantuoni E; Mendez-Tellez PA; Dinglas VD; Sevransky JE; Dennison Himmelfarb CR; Desai SV; Shanholtz C; Brower RG; Pronovost PJ
  • Protocols in the management of critical illness.
    Crit Care Volume: 16 Page(s): 306
    01/01/2012 Authors: Chang SY; Sevransky J; Martin GS
  • Another "negative" acute lung injury trial.
    Crit Care Med Volume: 40 Page(s): 315 - 316
    01/01/2012 Authors: Han S-H; Sevransky J
  • Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma.
    PLoS One Volume: 7 Page(s): e28268
    01/01/2012 Authors: Christie JD; Wurfel MM; Feng R; O'Keefe GE; Bradfield J; Ware LB; Christiani DC; Calfee CS; Cohen MJ; Matthay M
  • Social work in adult critical care: a national survey.
    Chest Volume: 140 Page(s): 1670 - 1672
    12/01/2011 Authors: Hartman-Shea K; Hahn AP; Kraus JF; Maygers J; Sevransky J; Cordts GA
  • Critical Illness Outcome Study: An Observational Study on Protocols and Mortality in Intensive Care Units.
    Open Access J Clin Trials Volume: 2011 Page(s): 55 - 65
    09/23/2011 Authors: Ali NA; Gutteridge D; Shahul S; Checkley W; Sevransky J; Martin GS
  • Short-term mortality prediction for acute lung injury patients: external validation of the Acute Respiratory Distress Syndrome Network prediction model.
    Crit Care Med Volume: 39 Page(s): 1023 - 1028
    05/01/2011 Authors: Damluji A; Colantuoni E; Mendez-Tellez PA; Sevransky JE; Fan E; Shanholtz C; Wojnar M; Pronovost PJ; Needham DM
  • Early identification of patients at risk of acute lung injury: evaluation of lung injury prediction score in a multicenter cohort study.
    Am J Respir Crit Care Med Volume: 183 Page(s): 462 - 470
    02/15/2011 Authors: Gajic O; Dabbagh O; Park PK; Adesanya A; Chang SY; Hou P; Anderson H; Hoth JJ; Mikkelsen ME; Gentile NT
  • 48 hours of cisatracurium reduced 90-day mortality in patients with early, severe ARDS
    ANNALS OF INTERNAL MEDICINE Volume: 154
    01/18/2011 Authors: Sevransky J
  • ACP Journal Club. 48 hours of cisatracurium reduced 90-day mortality in patients with early, severe ARDS.
    Ann Intern Med Volume: 154 Page(s): JC1 - JC3
    01/18/2011 Authors: Sevransky J
  • Organizational Structure Of 27 Intensive Care Units In The United States: Critical Illness Outcomes Study (CIOS)
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 183
    01/01/2011 Authors: Checkley W; Martin GS; Brown S; Chang SY; Dabbagh O; Fremont R; Girard TD; Howell M; Johnson S; O'Brien J
  • Short women with severe sepsis-related acute lung injury receive lung protective ventilation less frequently: an observational cohort study.
    Crit Care Volume: 15 Page(s): R262
    01/01/2011 Authors: Han S; Martin GS; Maloney JP; Shanholtz C; Barnes KC; Murray S; Sevransky JE
  • ORMDL3 And GSDML Gene Variants Associated With Risk And Severity Of Acute Lung Injury
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 183
    01/01/2011 Authors: Gao L; Murray T; Campbell M; Rafaels N; Maloney JP; Moss M; Martin GS; Shanholtz C; Herr D; Sevransky J
  • The role of the social worker in the adult critical care unit: a systematic review of the literature.
    Soc Work Health Care Volume: 50 Page(s): 143 - 157
    01/01/2011 Authors: Hartman-Shea K; Hahn AP; Fritz Kraus J; Cordts G; Sevransky J
  • EXTERNAL VALIDATION OF THE ARDS NETWORK SHORT-TERM MORTALITY PREDICTION MODEL FOR ACUTE LUNG INJURY (ALI)
    Volume: 38 Page(s): U173 - U173
    12/01/2010 Authors: Damluji A; Colancuoni E; Mendez-Tellez P; Sevransky J; Fan E; Shanholtz C; Wojnar M; Pronovost P; Needham D
  • SOCIAL WORK IN ADULT CRITICAL CARE: A NATIONAL SURVEY
    Volume: 38 Page(s): U226 - U226
    12/01/2010 Authors: Shea K; Hahn A; Kraus J; Maygers J; Sevransky J; Cordts G
  • Critical care trial design and interpretation: a primer.
    Crit Care Med Volume: 38 Page(s): 1882 - 1889
    09/01/2010 Authors: Sevransky JE; Checkley W; Martin GS
  • Human immunodeficiency virus infection and hospital mortality in acute lung injury patients.
    Crit Care Med Volume: 38 Page(s): 1530 - 1535
    07/01/2010 Authors: Mendez-Tellez PA; Damluji A; Ammerman D; Colantuoni E; Fan E; Sevransky JE; Shanholtz C; Gallant JE; Pronovost PJ; Needham DM
  • Long-term mortality and quality of life in sepsis: a systematic review.
    Crit Care Med Volume: 38 Page(s): 1276 - 1283
    05/01/2010 Authors: Winters BD; Eberlein M; Leung J; Needham DM; Pronovost PJ; Sevransky JE
  • Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury.
    Chest Volume: 137 Page(s): 288 - 296
    02/01/2010 Authors: Ware LB; Koyama T; Billheimer DD; Wu W; Bernard GR; Thompson BT; Brower RG; Standiford TJ; Martin TR; Matthay MA
  • Genome Wide Association (GWA) Identifies Functional Susceptibility Loci For Trauma-Associated Acute Lung Injury
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 181
    01/01/2010 Authors: Christie JD; Wurfel MM; O'Keefe G; Christiani DC; Ware LB; Calfee CS; Meyer N; Bradfield J; Kim C; Li M
  • PREDICTORS OF MORTALITY FOR ACUTE LUNG INJURY (ALI) PATIENTS WITH HIV INFECTION
    Volume: 37 Page(s): A351 - A351
    12/01/2009 Authors: Damluji A; Mendez-Tellez P; Ammerman D; Fan E; Gallant J; Sevransky J; Shanholtz C; Pronovost P; Johnson E; Needham D
  • GENDER AND USE OF LUNG PROTECTIVE VENTILATION(LPV) IN ACUTE LUNG INJURY(ALI)
    Volume: 37 Page(s): A359 - A359
    12/01/2009 Authors: Han S; Martin G; Maloney J; Barnes K; Shanholtz C; Murray S; Sevransky J
  • Is it time for intensivists to learn genomics?
    Crit Care Med Volume: 37 Page(s): 2852 - 2853
    10/01/2009 Authors: Sevransky J
  • Red blood cell transfusion practices in acute lung injury: what do patient factors contribute?
    Crit Care Med Volume: 37 Page(s): 1935 - 1940
    06/01/2009 Authors: Murphy DJ; Howard D; Muriithi A; Mendez-Tellez P; Sevransky J; Shanholtz C; Netzer G; Pronovost PJ; Needham DM
  • Clinical assessment of hemodynamically unstable patients.
    Curr Opin Crit Care Volume: 15 Page(s): 234 - 238
    06/01/2009 Authors: Sevransky J
  • Are intensive care factors associated with depressive symptoms 6 months after acute lung injury?
    Crit Care Med Volume: 37 Page(s): 1702 - 1707
    05/01/2009 Authors: Dowdy DW; Bienvenu OJ; Dinglas VD; Mendez-Tellez PA; Sevransky J; Shanholtz C; Needham DM
  • Is target population more important than patient location when evaluating tight glycemic control?
    Crit Care Med Volume: 37 Page(s): 741 - 742
    02/01/2009 Authors: Gibson BR; Sevransky JE
  • Mortality in sepsis versus non-sepsis induced acute lung injury.
    Crit Care Volume: 13 Page(s): R150
    01/01/2009 Authors: Sevransky JE; Martin GS; Shanholtz C; Mendez-Tellez PA; Pronovost P; Brower R; Needham DM
  • Variants in the Reactive Oxygen Species-Producing Enzyme Xanthine Oxidoreductase Gene Are Associated with Acute Lung Injury.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 179
    01/01/2009 Authors: Gao L; Murray T; Rafaels N; Grigoryev DN; Maloney JP; Moss M; Martin G; Shanholtz C; Garcia JGN; Sevransky J
  • SEPSIS IS NOT INDEPENDENTLY ASSOCIATED WITH MORTALITY IN ACUTE LUNG INJURY
    Volume: 36 Page(s): A78 - A78
    12/01/2008 Authors: Sevransky J; Mendez-Tellez P; Brower R; Pronovost P; Needham D; Martin G; Shanholtz C
  • A SYSTEMATIC REVIEW OF LONGTERM OUTCOMES IN PATIENTS WITH SEPSIS.
    Volume: 36 Page(s): A94 - A94
    12/01/2008 Authors: Eberlein M; Winters B; Needham D; Sevransky J
  • Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.
    Am J Respir Crit Care Med Volume: 178 Page(s): 710 - 720
    10/01/2008 Authors: Wurfel MM; Gordon AC; Holden TD; Radella F; Strout J; Kajikawa O; Ruzinski JT; Rona G; Black RA; Stratton S
  • More evidence that timing matters in the treatment of patients with sepsis.
    Crit Care Med Volume: 36 Page(s): 2932 - 2933
    10/01/2008 Authors: Sevransky J
  • Intensive care unit hypoglycemia predicts depression during early recovery from acute lung injury.
    Crit Care Med Volume: 36 Page(s): 2726 - 2733
    10/01/2008 Authors: Dowdy DW; Dinglas V; Mendez-Tellez PA; Bienvenu OJ; Sevransky J; Dennison CR; Shanholtz C; Needham DM
  • Reasons for nonenrollment in a clinical trial of acute lung injury.
    Chest Volume: 134 Page(s): 719 - 723
    10/01/2008 Authors: Glassberg AE; Luce JM; Matthay MA; National Heart, Lung, and Blood Institute Clinical Trials Network
  • Pulmonary vs nonpulmonary sepsis and mortality in acute lung injury.
    Chest Volume: 134 Page(s): 534 - 538
    09/01/2008 Authors: Sevransky JE; Martin GS; Mendez-Tellez P; Shanholtz C; Brower R; Pronovost PJ; Needham DM
  • Patient and intensive care unit organizational factors associated with low tidal volume ventilation in acute lung injury.
    Crit Care Med Volume: 36 Page(s): 1463 - 1468
    05/01/2008 Authors: Umoh NJ; Fan E; Mendez-Tellez PA; Sevransky JE; Dennison CR; Shanholtz C; Pronovost PJ; Needham DM
  • The Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008.
    Crit Care Resusc Volume: 10 Page(s): 8
    03/01/2008 Authors: Hicks P; Cooper DJ; Australian and New Zealand Intensive Care Society (ANZICS) Board and Clinical Trials Group Executive Committee
  • Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008.
    Crit Care Med Volume: 36 Page(s): 296 - 327
    01/01/2008 Authors: Dellinger RP; Levy MM; Carlet JM; Bion J; Parker MM; Jaeschke R; Reinhart K; Angus DC; Brun-Buisson C; Beale R
  • Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008.
    Intensive Care Med Volume: 34 Page(s): 17 - 60
    01/01/2008 Authors: Dellinger RP; Levy MM; Carlet JM; Bion J; Parker MM; Jaeschke R; Reinhart K; Angus DC; Brun-Buisson C; Beale R
  • Pulmonary vs. non pulmonary source of sepsis is not associated with mortality in sepsis-induced acute lung injury
    Volume: 35 Page(s): A157 - A157
    12/01/2007 Authors: Sevransky J; Mendez-Tellez P; Pronovost P; Brower R; Needham D; Shanholtz C; Martin G
  • Intensive care unit exposures for long-term outcomes research: development and description of exposures for 150 patients with acute lung injury.
    J Crit Care Volume: 22 Page(s): 275 - 284
    12/01/2007 Authors: Needham DM; Wang W; Desai SV; Mendez-Tellez PA; Dennison CR; Sevransky J; Shanholtz C; Ciesla N; Spillman K; Pronovost PJ
  • Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome.
    Crit Care Med Volume: 35 Page(s): 1821 - 1828
    08/01/2007 Authors: Ware LB; Matthay MA; Parsons PE; Thompson BT; Januzzi JL; Eisner MD; National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Clinical Trials Network
  • Macrophage migration inhibitory factor in acute lung injury: expression, biomarker, and associations.
    Transl Res Volume: 150 Page(s): 18 - 29
    07/01/2007 Authors: Gao L; Flores C; Fan-Ma S; Miller EJ; Moitra J; Moreno L; Wadgaonkar R; Simon B; Brower R; Sevransky J
  • Polymorphisms in the myosin light chain kinase gene that confer risk of severe sepsis are associated with a lower risk of asthma.
    J Allergy Clin Immunol Volume: 119 Page(s): 1111 - 1118
    05/01/2007 Authors: Gao L; Grant AV; Rafaels N; Stockton-Porter M; Watkins T; Gao P; Chi P; Muoz M; Watson H; Dunston G
  • Higher urine nitric oxide is associated with improved outcomes in patients with acute lung injury.
    Am J Respir Crit Care Med Volume: 175 Page(s): 256 - 262
    02/01/2007 Authors: McClintock DE; Ware LB; Eisner MD; Wickersham N; Thompson BT; Matthay MA; National Heart, Lung, and Blood Institute ARDS Network
  • The relative intensity of physical activity and the risk of stroke: A meta-analysis
    Volume: 62 Page(s): S19 - S19
    01/01/2007 Authors: Diep LB; Kim A; Jordon L; Sevransky J; Duggal M; Bhardwaj S; Konstantinos T; Xurantsin-Mills J
  • Myosin light chain kinase (MYLK) variants that confer increased risk of sepsis and acute lung injury are associated with asthma and associated phenotypes
    Volume: 119 Page(s): S146 - S147
    01/01/2007 Authors: Gao L; Grant A; Chi P; Gao P; Stockton M; Watson H; Hansel NN; Diette G; Dunston G; Mathias RA
  • Hemodynamic goals in randomized clinical trials in patients with sepsis: a systematic review of the literature.
    Crit Care Volume: 11 Page(s): R67
    01/01/2007 Authors: Sevransky JE; Nour S; Susla GM; Needham DM; Hollenberg S; Pronovost P
  • Preclinical trial of L-arginine monotherapy alone or with N-acetylcysteine in septic shock.
    Crit Care Med Volume: 34 Page(s): 2719 - 2728
    11/01/2006 Authors: Kalil AC; Sevransky JE; Myers DE; Esposito C; Vandivier RW; Eichacker P; Susla GM; Solomon SB; Csako G; Costello R
  • Higher urine desmosine levels are associated with mortality in patients with acute lung injury.
    Am J Physiol Lung Cell Mol Physiol Volume: 291 Page(s): L566 - L571
    10/01/2006 Authors: McClintock DE; Starcher B; Eisner MD; Thompson BT; Hayden DL; Church GD; Matthay MA; National Heart, Lung, Blood Institute Acute Respiratory Distress Syndrome Clinical Trials Network
  • Novel polymorphisms in the myosin light chain kinase gene confer risk for acute lung injury.
    Am J Respir Cell Mol Biol Volume: 34 Page(s): 487 - 495
    04/01/2006 Authors: Gao L; Grant A; Halder I; Brower R; Sevransky J; Maloney JP; Moss M; Shanholtz C; Yates CR; Meduri GU
  • Study protocol: The Improving Care of Acute Lung Injury Patients (ICAP) study.
    Crit Care Volume: 10 Page(s): R9
    02/01/2006 Authors: Needham DM; Dennison CR; Dowdy DW; Mendez-Tellez PA; Ciesla N; Desai SV; Sevransky J; Shanholtz C; Scharfstein D; Herridge MS
  • Prophylactic high-dose N(omega)-monomethyl-L-arginine prevents the late cardiac dysfunction associated with lethal tumor necrosis factor-alpha challenge in dogs.
    Shock Volume: 23 Page(s): 281 - 288
    03/01/2005 Authors: Sevransky J; Vandivier RW; Gerstenberger E; Correa R; Ferantz V; Banks SM; Danner RL; Eichacker PQ; Natanson C
  • Mechanical ventilation in sepsis-induced acute lung injury/acute respiratory distress syndrome: an evidence-based review.
    Crit Care Med Volume: 32 Page(s): S548 - S553
    11/01/2004 Authors: Sevransky JE; Levy MM; Marini JJ
  • Granulocyte colony-stimulating factor has differing effects comparing intravascular versus extravascular models of sepsis.
    J Trauma Volume: 57 Page(s): 618 - 625
    09/01/2004 Authors: Sevransky JE; Parent C; Cui X; Karzai W; Fitz Y; Banks SM; Gerstenberger E; Danner RL; Natanson C; Eichacker PQ
  • Respiratory failure in elderly patients.
    Clin Geriatr Med Volume: 19 Page(s): 205 - 224
    02/01/2003 Authors: Sevransky JE; Haponik EF
  • Low adherence by internists to use of maximal barrier precautions during insertion of central venous catheters.
    Volume: 30 Page(s): A99 - A99
    12/01/2002 Authors: Rubinson L; Scott TY; Sevransky JE; Diette GB
  • A 39-year-old man with hip pain and respiratory failure.
    Chest Volume: 121 Page(s): 1345 - 1349
    04/01/2002 Authors: Dooley KE; Sinha SR; Haponik E; Conwit R; Sevransky JE
  • Clinical trials in sepsis: an update.
    Curr Opin Anaesthesiol Volume: 13 Page(s): 125 - 129
    04/01/2000 Authors: Sevransky J; Natanson C
  • Anti-inflammatory agents increase or decrease survival dependent on the severity of infectious challenge in sepsis models.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 159 Page(s): A614 - A614
    03/01/1999 Authors: Parent C; Esposito C; Kalil A; Natanson C; Sevransky J; Danner R; Banks S; Roettinger A; Obeid J; Fitz Y
  • The effect of L-NMMA on TNF induced cardiac dysfunction
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 159 Page(s): A245 - A245
    03/01/1999 Authors: Sevransky JE; Vandivier RW; Quezado ZMN; Eichacker PQ; Danner RL; Banks SM; Bacher J; Thomas ML; Natanson C
  • Effects of L-NMMA and fluid loading on TNF-induced cardiovascular dysfunction in dogs.
    Am J Respir Crit Care Med Volume: 157 Page(s): 1397 - 1405
    05/01/1998 Authors: Quezado ZM; Karzai W; Danner RL; Freeman BD; Yan L; Eichacker PQ; Banks SM; Cobb JP; Cunnion RE; Quezado MJ
  • Tyrphostin AG 556 improves survival and reduces multiorgan failure in canine Escherichia coli peritonitis.
    J Clin Invest Volume: 99 Page(s): 1966 - 1973
    04/15/1997 Authors: Sevransky JE; Shaked G; Novogrodsky A; Levitzki A; Gazit A; Hoffman A; Elin RJ; Quezado ZM; Freeman BD; Eichacker PQ
  • Critical care medicine.
    Volume: 275 Page(s): 1799 - 1800
    06/19/1996 Authors: Hollenberg SM; Parrillo JE
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