Jeff Sands MD
- Department of Medicine
Professor Emeritus
- (404) 727-2525
- jeff.sands@emory.edu
-
1815 Crest Oaks Place NE
Overview
RESEARCH
Dr. Sands research focuses on the molecular physiology of urea transporters, aquaporins, and the urine concentrating mechanism, and the translation of these basic research findings into novel therapies for nephrogenic diabetes insipidus.
BIOGRAPHY
Dr. Sands is a graduate of Harvard College and Boston University School of Medicine. He trained in Medicine at the University of Chicago and the NIHs National Heart, Lung, and Blood Institute (NHLBI). Following research fellowship training in the Laboratory of Kidney and Electrolyte Metabolism, NHLBI, NIH, he proceeded to a clinical nephrology fellowship at Emory.
Dr. Sands is a Founder and Chief Medical Officer of NephroDI Therapeutics. NephroDI Therapeutics is developing a small molecule therapeutic for congenital nephrogenic diabetes insipidus, which is a pediatric orphan disease. Dr. Sands is considered a key opinion leader in nephrogenic diabetes insipidus.
Dr. Sands joined the Emory faculty as an Assistant Professor in 1989, was promoted to Associate Professor in 1993, and to Professor 1998. He served as the Juha P. Kokko Professor of Medicine and Renal Division Director at Emory from 2002-2024. He served as Executive Vice-Chair of Medicine from 2009-2015 and as Associate Dean for Clinical and Translational Research from 2006-2010. He is currently the Juha P. Kokko Professor Emeritus of Medicine at Emory.
Dr. Sands served as Editor-in-Chief of the American Journal of Physiology Renal from 2001-2007, chair of the 2004 American Society of Nephrology Program Committee, chair of the American Heart Association Kidney Council from 2008-2010, a member of the NIDDK Board of Scientific Councilors from 2008-2013, and the 91st President of the American Physiological Society from 2018-2019. He is a member of the American Association of Physicians, the American Society for Clinical Investigation, and the American Clinical and Climatological Association. Dr. Sands has served on study sections for the NIH, AHA, and NKF.
Dr. Sands has received several honors, including: the Distinguished Alumnus Award from Boston University School of Medicine in 2006; the Carl Gottschalk Distinguished Lecturer for the APS Renal Section in 2013; the Distinguished Achievement Award from the American Heart Association in 2014; the Barry M. Brenner Endowed Lecturer for the American Society of Nephrology in 2015; the Homer W. Smith Award from the American Society of Nephrology in 2022; and the Robert W. Berliner Award for the APS Renal Section in 2025. He was awarded the Doctor Medicinae Honoris Causa (dr.med.h.c.) from Aarhus University in Denmark in 2018. He has authored over 180 peer-reviewed manuscripts, 105 invited reviews or book chapters, and has co-edited a book. Dr. Sands has given 40 invited talks at national or international scientific meetings and over 110 invited lectures at other U.S. or international universities.
Academic Appointment
- Juha P. Kokko Professor Emeritus of Medicine, Medicine, Emory University School of Medicine
Education
Degrees
- MD from Boston University School of Medicine
- BA from Harvard College
Research
Publications
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Thick Ascending Limb Specific Inactivation of Myh9 and Myh10 Myosin Motors Results in Progressive Kidney Disease and Drives Sex-specific Cellular Adaptation in the Distal Nephron and Collecting Duct.
Function (Oxf) Volume: 6
02/12/2025 Authors: Otterpohl KL; Busselman BW; Zimmerman JL; Mukherjee M; Evans C; Graber K; Thakkar VP; Johnston JG; Ilyas A; Gumz ML -
Longitudinal Renal Function Degradation Among Florida Agricultural Workers.
J Occup Environ Med Volume: 66 Page(s): 694 - 705
09/01/2024 Authors: Chicas RC; Elon L; Xiuhtecutli N; Liang D; Houser MC; Mwarumba T; Berra L; Hertzberg V; Sands JM; McCauley L -
Renoprotective Effects of Daprodustat in Patients with Chronic Kidney Disease and Renal Anemia.
Int J Mol Sci Volume: 25
08/30/2024 Authors: Shimada Y; Izumi Y; Yasuoka Y; Oshima T; Nagaba Y; Nanami M; Sands JM; Takahashi N; Kawahara K; Nonoguchi H -
Tubular Endogenous Erythropoietin Protects Renal Function against Ischemic Reperfusion Injury.
Int J Mol Sci Volume: 25
01/19/2024 Authors: Yasuoka Y; Izumi Y; Fukuyama T; Oshima T; Yamazaki T; Uematsu T; Kobayashi N; Nanami M; Shimada Y; Nagaba Y -
The impact of heat exposures on biomarkers of AKI and plasma metabolome among agricultural and non-agricultural workers.
Environ Int Volume: 180 Page(s): 108206
10/01/2023 Authors: Chicas RC; Wang Y; Jennifer Weil E; Elon L; Xiuhtecutli N; C Houser M; Jones DP; M Sands J; Hertzberg V; McCauley L -
A Pilot Study Examining the Use of Ultrasound to Measure Intravascular Volume Status in Agricultural Workers in a Field-Based Research Setting.
J Occup Environ Med Volume: 65 Page(s): 685 - 688
08/01/2023 Authors: Suarez JJ; Elon L; Rangel-Rodriguez A; Xiuhtecutli N; Houser MC; Hertzberg V; McCauley L; Sands JM; Chicas RC -
Aldosterone Contributes to Vasopressin Escape through Changes in Water and Urea Transport.
Biomedicines Volume: 11
06/27/2023 Authors: Wang Y; LaRocque LM; Ruiz JA; Rodriguez EL; Sands JM; Klein JD -
Progress in the Detection of Erythropoietin in Blood, Urine, and Tissue.
Molecules Volume: 28
05/30/2023 Authors: Yasuoka Y; Izumi Y; Sands JM; Kawahara K; Nonoguchi H -
Phosphatases Decrease Water and Urea Permeability in Rat Inner Medullary Collecting Ducts.
Int J Mol Sci Volume: 24
03/31/2023 Authors: Wang Y; Klein JD; Sands JM -
The Health Status of Hispanic Agricultural Workers in Georgia and Florida.
J Immigr Minor Health Volume: 24 Page(s): 1129 - 1136
10/01/2022 Authors: Chicas RC; Elon L; Houser MC; Mutic A; Gallegos EI; Smith DJ; Modly L; Xiuhtecutli N; Hertzberg VS; Flocks J -
Empagliflozin Accelerates Escape from Vasopressin in Rats.
FASEB J Volume: 36 Suppl 1
05/01/2022 Authors: Eubanks EE; Rodriguez EL; Klein JD; Sands JM -
Aldosterone Regulates Vasopressin Escape through Changes in Water and Urea Transporters.
FASEB J Volume: 36 Suppl 1
05/01/2022 Authors: Wang Y; LaRocque LM; Sands JM; Klein JD -
Hydration Interventions Among Agricultural Workers: A Pilot Study.
J Occup Environ Med Volume: 64 Page(s): e357 - e359
05/01/2022 Authors: Chicas R; Suarez J; Elon L; Xiuhtecutli N; House MC; Berra L; Sands JM; Hertzberg V; McCauley L -
Effects of Roxadustat on Erythropoietin Production in the Rat Body.
Molecules Volume: 27
02/08/2022 Authors: Yasuoka Y; Izumi Y; Fukuyama T; Omiya H; Pham TD; Inoue H; Oshima T; Yamazaki T; Uematsu T; Kobayashi N -
COVID-19 and Agricultural Workers: A Descriptive Study.
J Immigr Minor Health Volume: 24 Page(s): 58 - 64
02/01/2022 Authors: Chicas R; Xiuhtecutli N; Houser M; Glastra S; Elon L; Sands JM; McCauley L; Hertzberg V -
Inflammation-Related Factors Identified as Biomarkers of Dehydration and Subsequent Acute Kidney Injury in Agricultural Workers.
Biol Res Nurs Volume: 23 Page(s): 676 - 688
10/01/2021 Authors: Houser MC; Mac V; Smith DJ; Chicas RC; Xiuhtecutli N; Flocks JD; Elon L; Tansey MG; Sands JM; McCauley L -
Effects of Angiotensin II on Erythropoietin Production in the Kidney and Liver.
Molecules Volume: 26
09/05/2021 Authors: Yasuoka Y; Izumi Y; Fukuyama T; Inoue H; Oshima T; Yamazaki T; Uematsu T; Kobayashi N; Shimada Y; Nagaba Y -
Adaptive physiological water conservation explains hypertension and muscle catabolism in experimental chronic renal failure.
Acta Physiol (Oxf) Volume: 232 Page(s): e13629
05/01/2021 Authors: Kovarik JJ; Morisawa N; Wild J; Marton A; Takase-Minegishi K; Minegishi S; Daub S; Sands JM; Klein JD; Bailey JL -
An AMPK activator as a therapeutic option for congenital nephrogenic diabetes insipidus.
JCI Insight Volume: 6
04/22/2021 Authors: Klein JD; Khanna I; Pillarisetti R; Hagan RA; LaRocque LM; Rodriguez EL; Sands JM -
Adrenomedullin Inhibits Osmotic Water Permeability in Rat Inner Medullary Collecting Ducts.
Cells Volume: 9
11/24/2020 Authors: Ma F; Chen G; Rodriguez EL; Klein JD; Sands JM; Wang Y -
Differentiation of endogenous erythropoietin and exogenous ESAs by Western blotting.
Heliyon Volume: 6 Page(s): e05389
11/01/2020 Authors: Yasuoka Y; Fukuyama T; Izumi Y; Yamashita T; Nakayama Y; Inoue H; Yanagita K; Oshima T; Yamazaki T; Uematsu T -
Ethical challenges in nephrology: a call for action.
Nat Rev Nephrol Volume: 16 Page(s): 603 - 613
10/01/2020 Authors: Martin DE; Harris DCH; Jha V; Segantini L; Demme RA; Le TH; McCann L; Sands JM; Vong G; Wolpe PR -
Using the payback framework to evaluate the outcomes of pilot projects supported by the Georgia Clinical and Translational Science Alliance.
J Clin Transl Sci Volume: 5 Page(s): e48
09/11/2020 Authors: Rollins L; Llewellyn N; Ngaiza M; Nehl E; Carter DR; Sands JM -
Inhibition of urea transporter ameliorates uremic cardiomyopathy in chronic kidney disease.
FASEB J Volume: 34 Page(s): 8296 - 8309
06/01/2020 Authors: Kuma A; Wang XH; Klein JD; Tan L; Naqvi N; Rianto F; Huang Y; Yu M; Sands JM -
Erythropoietin production by the kidney and the liver in response to severe hypoxia evaluated by Western blotting with deglycosylation.
Physiol Rep Volume: 8 Page(s): e14485
06/01/2020 Authors: Yasuoka Y; Fukuyama T; Izumi Y; Nakayama Y; Inoue H; Yanagita K; Oshima T; Yamazaki T; Uematsu T; Kobayashi N -
UT-A1/A3 knockout mice show reduced fibrosis following unilateral ureteral obstruction.
Am J Physiol Renal Physiol Volume: 318 Page(s): F1160 - F1166
05/01/2020 Authors: Rianto F; Kuma A; Ellis CL; Hassounah F; Rodriguez EL; Wang XH; Sands JM; Klein JD -
Aldosterone Decreases Vasopressin-Stimulated Water Reabsorption in Rat Inner Medullary Collecting Ducts.
Cells Volume: 9
04/14/2020 Authors: Wang Y; Ma F; Rodriguez EL; Klein JD; Sands JM -
An Exciting Time to Be an APS Member.
Physiology (Bethesda) Volume: 34 Page(s): 376 - 378
11/01/2019 Authors: Hay M; Sands J; Samuelson L -
E3 ligase MDM2 mediates urea transporter-A1 ubiquitination under either constitutive or stimulatory conditions.
Am J Physiol Renal Physiol Volume: 317 Page(s): F1331 - F1341
11/01/2019 Authors: Su H; Ye C; Sands JM; Zhang C -
High urea induces depression and LTP impairment through mTOR signalling suppression caused by carbamylation.
EBioMedicine Volume: 48 Page(s): 478 - 490
10/01/2019 Authors: Wang H; Huang B; Wang W; Li J; Chen Y; Flynn T; Zhao M; Zhou Z; Lin X; Zhang Y -
Regulation of renal urea and water transport: implications for therapy of nephrogenic diabetes insipidus
Volume: 227 Page(s): 20 - 21
09/01/2019 Authors: Sands JM; Klein JD -
Translating kidney fibrosis: Role of the EP2 receptor.
Acta Physiol (Oxf) Volume: 227 Page(s): e13318
09/01/2019 Authors: Sands JM -
Inner Medullary Urea Transporters Contribute to Development of Renal Fibrosis in Mice With Unilateral Ureteral Obstruction
Volume: 33
04/01/2019 Authors: Rianto F; Ellis CL; Hassounah F; Wang XH; Klein JD; Sands JM -
Age-related decline in urine concentration may not be universal: Comparative study from the U.S. and two small-scale societies.
Am J Phys Anthropol Volume: 168 Page(s): 705 - 716
04/01/2019 Authors: Rosinger AY; Pontzer H; Raichlen DA; Wood BM; Tanner SN; Sands JM -
Lack of urea transporters, UT-A1 and UT-A3, increases nitric oxide accumulation to dampen medullary sodium reabsorption through ENaC.
Volume: 316 Page(s): F539 - F549
03/01/2019 Authors: Rogers RT; Sun MA; Yue Q; Bao H-F; Sands JM; Blount MA; Eaton DC -
GDE5 inhibition accumulates intracellular glycerophosphocholine and suppresses adipogenesis at a mitotic clonal expansion stage.
Am J Physiol Cell Physiol Volume: 316 Page(s): C162 - C174
02/01/2019 Authors: Okazaki Y; Nakamura K; Takeda S; Yoshizawa I; Yoshida F; Ohshima N; Izumi T; Klein JD; Kumrungsee T; Sands JM -
Glucagon infusion alters the hyperpolarized 13 C-urea renal hemodynamic signature.
NMR Biomed Volume: 32 Page(s): e4028
01/01/2019 Authors: Qi H; Mariager C; Nielsen PM; Schroeder M; Lindhardt J; Nrregaard R; Klein JD; Sands JM; Laustsen C -
APS: Moving Forward to Aid Our Membership.
Physiology (Bethesda) Volume: 33 Page(s): 370 - 371
11/01/2018 Authors: Sands JM; Hay M; Brown D -
Ascending Vasa Recta Are Angiopoietin/Tie2-Dependent Lymphatic-Like Vessels.
J Am Soc Nephrol Volume: 29 Page(s): 1097 - 1107
04/01/2018 Authors: Kenig-Kozlovsky Y; Scott RP; Onay T; Carota IA; Thomson BR; Gil HJ; Ramirez V; Yamaguchi S; Tanna CE; Heinen S -
GRHL2 Is Required for Collecting Duct Epithelial Barrier Function and Renal Osmoregulation.
J Am Soc Nephrol Volume: 29 Page(s): 857 - 868
03/01/2018 Authors: Hinze C; Ruffert J; Walentin K; Himmerkus N; Nikpey E; Tenstad O; Wiig H; Mutig K; Yurtdas ZY; Klein JD -
Is age-related decline in urine concentrating ability universal? Hydration biomarkers from the United States and Bolivian Amazon
Volume: 30
03/01/2018 Authors: Rosinger A; Sands JM; Tanner SN -
APS: The Times They Are A-Changin'.
Physiology (Bethesda) Volume: 32 Page(s): 400 - 401
11/01/2017 Authors: Brown D; Sands JM; Reckelhoff JF -
High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation.
J Clin Invest Volume: 127 Page(s): 1944 - 1959
05/01/2017 Authors: Kitada K; Daub S; Zhang Y; Klein JD; Nakano D; Pedchenko T; Lantier L; LaRocque LM; Marton A; Neubert P -
Identification of a Novel UT-B Urea Transporter in Human Urothelial Cancer.
Front Physiol Volume: 8 Page(s): 245
01/01/2017 Authors: Hou R; Alemozaffar M; Yang B; Sands JM; Kong X; Chen G -
Phosphatase inhibition increases AQP2 accumulation in the rat IMCD apical plasma membrane.
Am J Physiol Renal Physiol Volume: 311 Page(s): F1189 - F1197
12/01/2016 Authors: Ren H; Yang B; Ruiz JA; Efe O; Ilori TO; Sands JM; Klein JD -
Physiological insights into novel therapies for nephrogenic diabetes insipidus.
Am J Physiol Renal Physiol Volume: 311 Page(s): F1149 - F1152
12/01/2016 Authors: Sands JM; Klein JD -
Effect of Dapagliflozin Treatment on Fluid and Electrolyte Balance in Diabetic Rats.
Am J Med Sci Volume: 352 Page(s): 517 - 523
11/01/2016 Authors: Chen L; LaRocque LM; Efe O; Wang J; Sands JM; Klein JD -
Urea transport and clinical potential of urearetics.
Curr Opin Nephrol Hypertens Volume: 25 Page(s): 444 - 451
09/01/2016 Authors: Klein JD; Sands JM -
Urea Transporter B and MicroRNA-200c Differ in Kidney Outer Versus Inner Medulla Following Dehydration.
Am J Med Sci Volume: 352 Page(s): 296 - 301
09/01/2016 Authors: Wang J; Wang XH; Wang H; Chen L; Klein JD; Sands JM -
Metformin improves urine concentration in rodents with nephrogenic diabetes insipidus.
JCI Insight Volume: 1
07/21/2016 Authors: Efe O; Klein JD; LaRocque LM; Ren H; Sands JM -
Modulation of kidney urea transporter UT-A3 activity by alpha2,6-sialylation.
Pflugers Arch Volume: 468 Page(s): 1161 - 1170
07/01/2016 Authors: Qian X; Sands JM; Song X; Chen G -
Water, Water Everywhere: A New Cause and a New Treatment for Nephrogenic Diabetes Insipidus.
J Am Soc Nephrol Volume: 27 Page(s): 1872 - 1874
07/01/2016 Authors: Sands JM -
Urea transporters and sweat response to uremia.
Physiol Rep Volume: 4
06/01/2016 Authors: Keller RW; Bailey JL; Wang Y; Klein JD; Sands JM -
Imaging Renal Urea Handling in Rats at Millimeter Resolution using Hyperpolarized Magnetic Resonance Relaxometry.
Tomography Volume: 2 Page(s): 125 - 135
06/01/2016 Authors: Reed GD; von Morze C; Verkman AS; Koelsch BL; Chaumeil MM; Lustig M; Ronen SM; Bok RA; Sands JM; Larson PEZ -
Metformin, an AMPK activator, stimulates the phosphorylation of aquaporin 2 and urea transporter A1 in inner medullary collecting ducts.
Am J Physiol Renal Physiol Volume: 310 Page(s): F1008 - F1012
05/15/2016 Authors: Klein JD; Wang Y; Blount MA; Molina PA; LaRocque LM; Ruiz JA; Sands JM -
Transgenic Restoration of Urea Transporter A1 Confers Maximal Urinary Concentration in the Absence of Urea Transporter A3.
J Am Soc Nephrol Volume: 27 Page(s): 1448 - 1455
05/01/2016 Authors: Klein JD; Wang Y; Mistry A; LaRocque LM; Molina PA; Rogers RT; Blount MA; Sands JM -
AMPK Stimulates Osmotic Water Permeability in Rat IMCDs
Volume: 30
04/01/2016 Authors: Wang Y; Efe O; LaRocque LM; Klein JD; Sands JM -
Activation of protein kinase C increases phosphorylation of the UT-A1 urea transporter at serine 494 in the inner medullary collecting duct.
Am J Physiol Cell Physiol Volume: 309 Page(s): C608 - C615
11/01/2015 Authors: Blount MA; Cipriani P; Redd SK; Ordas RJ; Black LN; Gumina DL; Hoban CA; Klein JD; Sands JM -
Urea and Ammonia Metabolism and the Control of Renal Nitrogen Excretion.
Clin J Am Soc Nephrol Volume: 10 Page(s): 1444 - 1458
08/07/2015 Authors: Weiner ID; Mitch WE; Sands JM -
Downregulation of urea transporter UT-A1 activity by 14-3-3 protein.
Am J Physiol Renal Physiol Volume: 309 Page(s): F71 - F78
07/01/2015 Authors: Feng X; Li Z; Du Y; Fu H; Klein JD; Cai H; Sands JM; Chen G -
Understanding renal physiology leads to therapeutic advances in renal disease.
Physiology (Bethesda) Volume: 30 Page(s): 171 - 172
05/01/2015 Authors: Sands JM -
Activation of protein kinase C- and Src kinase increases urea transporter A1 -2, 6 sialylation.
J Am Soc Nephrol Volume: 26 Page(s): 926 - 934
04/01/2015 Authors: Li X; Yang B; Chen M; Klein JD; Sands JM; Chen G -
AMPK Stimulates Urea Permeability and Urine Osmolality
Volume: 29
04/01/2015 Authors: Wang Y; Klein J; Sands J -
ENaC regulation by [Ca2+] i is determined by mitochondrial Ca2+ uptake
Volume: 29
04/01/2015 Authors: Thai T; Galarza-Paez L; Yu L; Bao HF; Klein J; Sands J; Eaton D -
AMPK Phosphorylates Urea Transporter A1 and Aquaporin 2 in Rat Inner Medullary Collecting Ducts
Volume: 29
04/01/2015 Authors: Ruiz J; Molina P; LaRocque L; Klein J; Sands J -
PKC- contributes to high NaCl-induced activation of NFAT5 (TonEBP/OREBP) through MAPK ERK1/2.
Am J Physiol Renal Physiol Volume: 308 Page(s): F140 - F148
01/15/2015 Authors: Wang H; Ferraris JD; Klein JD; Sands JM; Burg MB; Zhou X -
Vasopressin regulation of multisite phosphorylation of UT-A1 in the inner medullary collecting duct.
Am J Physiol Renal Physiol Volume: 308 Page(s): F49 - F55
01/01/2015 Authors: Hoban CA; Black LN; Ordas RJ; Gumina DL; Pulous FE; Sim JH; Sands JM; Blount MA -
NSAIDs Alter Phosphorylated Forms of AQP2 in the Inner Medullary Tip.
PLoS One Volume: 10 Page(s): e0141714
01/01/2015 Authors: Ren H; Yang B; Molina PA; Sands JM; Klein JD -
Thienoquinolins exert diuresis by strongly inhibiting UT-A urea transporters.
Am J Physiol Renal Physiol Volume: 307 Page(s): F1363 - F1372
12/15/2014 Authors: Ren H; Wang Y; Xing Y; Ran J; Liu M; Lei T; Zhou H; Li R; Sands JM; Yang B -
The kidney research national dialogue: gearing up to move forward.
Clin J Am Soc Nephrol Volume: 9 Page(s): 1806 - 1811
10/07/2014 Authors: Bonventre JV; Boulware LE; Dember LM; Freedman BI; Furth SL; Holzman LB; Ketchum CJ; Little MH; Mehrotra R; Moe SM -
Novel activators of aquaporin 2 membrane expression for the treatment of nephrogenic diabetes insipidus: less is more. Focus on "High-throughput chemical screening identifies AG-490 as a stimulator of aquaporin 2 membrane expression and urine concentration".
Am J Physiol Cell Physiol Volume: 307 Page(s): C595 - C596
10/01/2014 Authors: Sands JM; Blount MA -
Defining kidney biology to understand renal disease.
Clin J Am Soc Nephrol Volume: 9 Page(s): 809 - 811
04/01/2014 Authors: Little MH; Brown D; Humphreys BD; McMahon AP; Miner JH; Sands JM; Weisz OA; Mullins C; Hoshizaki D; Kidney Research National Dialogue (KRND) -
ENaC activity is increased in isolated, split-open cortical collecting ducts from protein kinase C knockout mice.
Am J Physiol Renal Physiol Volume: 306 Page(s): F309 - F320
02/01/2014 Authors: Bao H-F; Thai TL; Yue Q; Ma H-P; Eaton AF; Cai H; Klein JD; Sands JM; Eaton DC -
Genes and proteins of urea transporters.
Subcell Biochem Volume: 73 Page(s): 45 - 63
01/01/2014 Authors: Sands JM; Blount MA -
Advances in understanding the urine-concentrating mechanism.
Volume: 76 Page(s): 387 - 409
01/01/2014 Authors: Sands JM; Layton HE -
Overview and historical perspective.
Subcell Biochem Volume: 73 Page(s): 1 - 5
01/01/2014 Authors: Yang B; Sands JM -
Activation of the cAMP/PKA pathway induces UT-A1 urea transporter monoubiquitination and targets it for lysosomal degradation.
Am J Physiol Renal Physiol Volume: 305 Page(s): F1775 - F1782
12/15/2013 Authors: Su H; Chen M; Sands JM; Chen G -
Urea transporter inhibitors: en route to new diuretics.
Chem Biol Volume: 20 Page(s): 1201 - 1202
10/24/2013 Authors: Sands JM -
Small GTPase Rab14 down-regulates UT-A1 urea transport activity through enhanced clathrin-dependent endocytosis.
FASEB J Volume: 27 Page(s): 4100 - 4107
10/01/2013 Authors: Su H; Liu B; Frhlich O; Ma H; Sands JM; Chen G -
DUPLICATION OF THE UREA TRANSPORTER B GENE (KIDD BLOOD GROUP) IN A KINDRED WITH FAMILIAL AZOTEMIA
VOX SANGUINIS Volume: 105 Page(s): 30 - 31
06/01/2013 Authors: Haer-Wigman L; Linthorst GE; Sands JM; Klein JD; Thai TL; Verhoeven AJ; van Zwieten R; Folman C; Jansweijer MC; Knegt LC -
Increased UT-A1 ubiquitination is partially due to decreased deubiquitination activity in Streptozotocin-induced diabetic rat kidney inner medulla
Volume: 27
04/01/2013 Authors: Su H; Ilori TO; Klein JD; Sands JM; Chen G -
TRANSGENIC MICE EXPRESSING UT-A1, BUT LACKING UT-A3, HAVE INTACT URINE CONCENTRATING ABILITY
Volume: 27
04/01/2013 Authors: Klein JD; Froehlich O; Mistry AC; Kent KJ; Martin CF; Sands JM -
Mice lacking protein kinase C alpha show enhanced membrane localization and activity of the epithelial sodium channel (ENaC) in the renal cortical collecting duct
Volume: 27
04/01/2013 Authors: Bao H-F; Yue Q; Thai TL; Klein JD; Sands JM; Eaton DC -
Role of protein kinase C- in hypertonicity-stimulated urea permeability in mouse inner medullary collecting ducts.
Am J Physiol Renal Physiol Volume: 304 Page(s): F233 - F238
01/15/2013 Authors: Wang Y; Klein JD; Froehlich O; Sands JM -
Erlotinib preserves renal function and prevents salt retention in doxorubicin treated nephrotic rats.
PLoS One Volume: 8 Page(s): e54738
01/01/2013 Authors: Bou Matar RN; Klein JD; Sands JM -
Urine concentration in the diabetic mouse requires both urea and water transporters.
Am J Physiol Renal Physiol Volume: 304 Page(s): F103 - F111
01/01/2013 Authors: Ilori TO; Blount MA; Martin CF; Sands JM; Klein JD -
Molecular mechanisms of urea transport in health and disease.
Pflugers Arch Volume: 464 Page(s): 561 - 572
12/01/2012 Authors: Klein JD; Blount MA; Sands JM -
Urine concentrating and diluting ability during aging.
J Gerontol A Biol Sci Med Sci Volume: 67 Page(s): 1352 - 1357
12/01/2012 Authors: Sands JM -
Forskolin stimulation promotes urea transporter UT-A1 ubiquitination, endocytosis, and degradation in MDCK cells.
Am J Physiol Renal Physiol Volume: 303 Page(s): F1325 - F1332
11/01/2012 Authors: Su H; Carter CB; Laur O; Sands JM; Chen G -
The thick ascending limb and water channels: half-full or half-empty.
Am J Physiol Renal Physiol Volume: 303 Page(s): F619 - F620
09/01/2012 Authors: Sands JM -
Aquaporin 2: not just for moving water.
J Am Soc Nephrol Volume: 23 Page(s): 1443 - 1444
09/01/2012 Authors: Sands JM -
Dietary sodium intake in heart failure.
Circulation Volume: 126 Page(s): 479 - 485
07/24/2012 Authors: Gupta D; Georgiopoulou VV; Kalogeropoulos AP; Dunbar SB; Reilly CM; Sands JM; Fonarow GC; Jessup M; Gheorghiade M; Yancy C -
Lack of protein kinase C- leads to impaired urine concentrating ability and decreased aquaporin-2 in angiotensin II-induced hypertension.
Am J Physiol Renal Physiol Volume: 303 Page(s): F37 - F44
07/01/2012 Authors: Thai TL; Blount MA; Klein JD; Sands JM -
Monitoring urea transport in rat kidney in vivo using hyperpolarized C magnetic resonance imaging.
Am J Physiol Renal Physiol Volume: 302 Page(s): F1658 - F1662
06/15/2012 Authors: von Morze C; Bok RA; Sands JM; Kurhanewicz J; Vigneron DB -
Protein abundance of urea transporters and aquaporin 2 change differently in nephrotic pair-fed vs. non-pair-fed rats.
Am J Physiol Renal Physiol Volume: 302 Page(s): F1545 - F1553
06/15/2012 Authors: Bou Matar RN; Malik B; Wang XH; Martin CF; Eaton DC; Sands JM; Klein JD -
Protein kinase C- mediates hypertonicity-stimulated increase in urea transporter phosphorylation in the inner medullary collecting duct.
Am J Physiol Renal Physiol Volume: 302 Page(s): F1098 - F1103
05/01/2012 Authors: Klein JD; Martin CF; Kent KJ; Sands JM -
Acute calcineurin inhibition with tacrolimus increases phosphorylated UT-A1.
Am J Physiol Renal Physiol Volume: 302 Page(s): F998 - F1004
04/15/2012 Authors: Ilori TO; Wang Y; Blount MA; Martin CF; Sands JM; Klein JD -
Rab14 GTPase downregulates urea transporter UT-A1 activity through enhanced clathrin-dependent endocytosis and protein degradation
Volume: 26
04/01/2012 Authors: Su H; Xu G; Carter CB; Froehlich O; Sands JM; Chen G -
The urea transporter UT-A1 is phosphorylated at serines 486 and 499 downstream of cyclic AMP production
Volume: 26
04/01/2012 Authors: Thai TL; Gumina DL; Ilori TO; Klein JD; Blount MA; Sands JM -
Role of PKC alpha in Hypertonicity-stimulated Urea Permeability
Volume: 26
04/01/2012 Authors: Wang Y; Klein JD; Froehlich O; Sands JM -
Forskolin stimulation promotes urea transporter UT-A1 ubiquitination, endocytosis and degradation in MDCK cells
FASEB JOURNAL Volume: 26
04/01/2012 Authors: Chen G; Su H; Carter CB; Froehlich O; Sands JM -
LACK OF PROTEIN KINASE C alpha LEADS TO IMPAIRED URINE CONCENTRATING ABILITY AND DECREASED AQUAPORIN-2 IN ANGIOTENSIN II-INDUCED HYPERTENSION
Volume: 60 Page(s): 425 - 425
01/01/2012 Authors: Thai TL; Blount MA; Klein JD; Sands JM -
ACUTE CALCINEURIN INHIBITION WITH TACROLIMUS INCREASES PHOSPHORYLATION OF UT-A1 AT SERINE 486
Volume: 60 Page(s): 385 - 385
01/01/2012 Authors: Ilori TO; Wang Y; Blount MA; Sands J; Klein JD -
PROTEIN ABUNDANCE OF UREA TRANSPORTERS AND AQUAPORIN 2 CHANGE DIFFERENTLY IN NEPHROTIC PAIR-FED VERSUS NON-PAIR-FED RATS
Volume: 60 Page(s): 384 - 384
01/01/2012 Authors: Matar BR; Sands J; Klein J -
Mature N-linked glycans facilitate UT-A1 urea transporter lipid raft compartmentalization.
FASEB J Volume: 25 Page(s): 4531 - 4539
12/01/2011 Authors: Chen G; Howe AG; Xu G; Frhlich O; Klein JD; Sands JM -
N-methyl-D-aspartate receptor subunit NR3a expression and function in principal cells of the collecting duct.
Am J Physiol Renal Physiol Volume: 301 Page(s): F44 - F54
07/01/2011 Authors: Sproul A; Steele SL; Thai TL; Yu S; Klein JD; Sands JM; Bell PD -
N-LINKED GLYCOSYLATION IS REQUIRED FOR UT-A1 UREA TRANSPORTER TRAFFICKING INTO THE MEMBRANE LIPID RAFT SUBDOMAINS
Volume: 25
04/01/2011 Authors: Chen G; Howe AG; Froehlich O; Klein JD; Sands JM -
Phosphorylation of UT-A1 at S486 and S499 is a Rapid and Non-Redundant Response to Increased Intercellular cAMP
Volume: 25
04/01/2011 Authors: Blount MA; Hoban CA; Gumina DL; Klein JD; Sands JM -
Lack of PKC alpha leads to Altered Urea Transporter UT-A1 and Aquaporin-2 in Angiotensin II-induced Hypertension
Volume: 25
04/01/2011 Authors: Thai TL; Klein JD; Sands JM -
QUALITY IMPROVEMENT PROJECT: IMPROVING CARDIOVASCULAR RISK FACTOR MODIFICATION IN CHRONIC KIDNEY DISEASE PATIENTS IN NEPHROLOGY FELLOW CONTINUITY CLINIC
Volume: 57 Page(s): A33 - A33
04/01/2011 Authors: Cobb J; Sarolia S; Ilori T; Sands J; Bailey J -
Increases in Aquaporins-2 cannot compensate for the loss of Urea transporters UT-A1 and UT-A3 in Diabetic animals
Volume: 25
04/01/2011 Authors: Ilori TO; Denson C; Sands J; Klein J -
The Urea Transporter UT-A1 is Directly Phosphorylated by PKC
Volume: 25
04/01/2011 Authors: Redd SK; Cipriani P; Ordas R; Klein JD; Blount MA; Sands JM -
Urea transport in the kidney.
Compr Physiol Volume: 1 Page(s): 699 - 729
04/01/2011 Authors: Klein JD; Blount MA; Sands JM -
Increased susceptibility to acute kidney injury due to endoplasmic reticulum stress in mice lacking tumor necrosis factor- and its receptor 1.
Kidney Int Volume: 79 Page(s): 613 - 623
03/01/2011 Authors: Huang L; Zhang R; Wu J; Chen J; Grosjean F; Satlin LH; Klein JD; Sands JM; Striker GE; Tan J -
MEMBRANE ACCUMULATION OF THE UREA TRANSPORTER IN THE DIABETIC RAT KIDNEY
Volume: 59 Page(s): 461 - 462
02/01/2011 Authors: Ilori TO; Thai T; Martin C; Blount MA; Sands JM; Klein JD -
DECREASED AQUAPORIN 2 AND UREA TRANSPORTER ABUNDANCES IN A RAT MODEL OF NEPHROTIC SYNDROME
Volume: 59 Page(s): 530 - 530
02/01/2011 Authors: Matar BR; Sands J; Klein J -
Regulation of renal urea transport by vasopressin.
Trans Am Clin Climatol Assoc Volume: 122 Page(s): 82 - 92
01/01/2011 Authors: Sands JM; Blount MA; Klein JD -
Internalization of UT-A1 urea transporter is dynamin dependent and mediated by both caveolae- and clathrin-coated pit pathways.
Am J Physiol Renal Physiol Volume: 299 Page(s): F1389 - F1395
12/01/2010 Authors: Huang H; Feng X; Zhuang J; Frhlich O; Klein JD; Cai H; Sands JM; Chen G -
Protein kinase C regulates urea permeability in the rat inner medullary collecting duct.
Am J Physiol Renal Physiol Volume: 299 Page(s): F1401 - F1406
12/01/2010 Authors: Wang Y; Klein JD; Liedtke CM; Sands JM -
Electrolytes in the aging.
Adv Chronic Kidney Dis Volume: 17 Page(s): 308 - 319
07/01/2010 Authors: Schlanger LE; Bailey JL; Sands JM -
Functional characterization of the central hydrophilic linker region of the urea transporter UT-A1: cAMP activation and snapin binding.
Am J Physiol Cell Physiol Volume: 298 Page(s): C1431 - C1437
06/01/2010 Authors: Mistry AC; Mallick R; Klein JD; Sands JM; Frhlich O -
Neuronal expression of sodium/bicarbonate cotransporter NBCn1 (SLC4A7) and its response to chronic metabolic acidosis.
Am J Physiol Cell Physiol Volume: 298 Page(s): C1018 - C1028
05/01/2010 Authors: Park HJ; Rajbhandari I; Yang HS; Lee S; Cucoranu D; Cooper DS; Klein JD; Sands JM; Choi I -
Suppression subtractive hybridization analysis of low-protein diet- and vitamin D-induced gene expression from rat kidney inner medullary base.
Physiol Genomics Volume: 41 Page(s): 203 - 211
05/01/2010 Authors: Chen G; Yang Y; Frhlich O; Klein JD; Sands JM -
Hypertonicity Increases Urea Permeability through PKC in Inner Medullary Collecting Ducts
FASEB JOURNAL Volume: 24
04/01/2010 Authors: Wang Y; Klein JD; Sands JM -
The Role of Nitric Oxide in the Urine Concentration Mechanism in Diabetic Rats
FASEB JOURNAL Volume: 24
04/01/2010 Authors: Cipriani P; Kim SL; Klein JD; Denson CE; Sim JH; Sands JM; Blount MA -
Hyperosmolarity stimulates heat shock protein 40 and 70 interaction with UT-A1 urea transporter
FASEB JOURNAL Volume: 24
04/01/2010 Authors: Chen G; Feng X; Frohlich O; Yang Y; Klein JD; Sands JM -
An SP/TP motif in the N-terminal cytoplasmic domain of UT-A3 as potential activation site of UT-A3-mediated urea transport
FASEB JOURNAL Volume: 24
12/31/2010 Authors: Mistry A; Mallick R; Klein JD; Sands JM; Froehlich O -
Phosphorylation of UT-A1 on serine 486 correlates with membrane accumulation and urea transport activity in both rat IMCDs and cultured cells.
Am J Physiol Renal Physiol Volume: 298 Page(s): F935 - F940
04/01/2010 Authors: Klein JD; Blount MA; Frhlich O; Denson CE; Tan X; Sim JH; Martin CF; Sands JM -
Expression of transporters involved in urine concentration recovers differently after cessation of lithium treatment.
Am J Physiol Renal Physiol Volume: 298 Page(s): F601 - F608
03/01/2010 Authors: Blount MA; Sim JH; Zhou R; Martin CF; Lu W; Sands JM; Klein JD -
THE ROLE OF NITRIC OXIDE IN THE URINE CONCENTRATION MECHANISM IN DIABETIC RATS
Volume: 58 Page(s): 427 - 427
02/01/2010 Authors: Cipriani P; Kim SL; Klein JD; Denson CE; Sim JH; Sands JM; Blount MA -
The N-terminal 81-aa fragment is critical for UT-A1 urea transporter bioactivity.
J Epithel Biol Pharmacol Volume: 3 Page(s): 34 - 39
01/01/2010 Authors: Huang H; Yang Y; Eaton DC; Sands JM; Chen G -
Urinary concentration and dilution in the aging kidney.
Semin Nephrol Volume: 29 Page(s): 579 - 586
11/01/2009 Authors: Sands JM -
Epac regulates UT-A1 to increase urea transport in inner medullary collecting ducts.
J Am Soc Nephrol Volume: 20 Page(s): 2018 - 2024
09/01/2009 Authors: Wang Y; Klein JD; Blount MA; Martin CF; Kent KJ; Pech V; Wall SM; Sands JM -
Syntaxin specificity of aquaporins in the inner medullary collecting duct.
Am J Physiol Renal Physiol Volume: 297 Page(s): F292 - F300
08/01/2009 Authors: Mistry AC; Mallick R; Klein JD; Weimbs T; Sands JM; Frhlich O -
Geriatric nephrology: old or new subspecialty.
Clin Geriatr Med Volume: 25 Page(s): 311 - 324
08/01/2009 Authors: Schlanger LE; Bailey JL; Sands JM -
Caveolin-1 directly interacts with UT-A1 urea transporter: the role of caveolae/lipid rafts in UT-A1 regulation at the cell membrane.
Am J Physiol Renal Physiol Volume: 296 Page(s): F1514 - F1520
06/01/2009 Authors: Feng X; Huang H; Yang Y; Frhlich O; Klein JD; Sands JM; Chen G -
The physiology of urinary concentration: an update.
Semin Nephrol Volume: 29 Page(s): 178 - 195
05/01/2009 Authors: Sands JM; Layton HE -
Epac Regulation of Urea Transport and the UT-A1 Urea Transporter in Rat Inner Medullary Collecting Duct
FASEB JOURNAL Volume: 23
04/01/2009 Authors: Wang Y; Klein JD; Martin C; Kent K; Wall SM; Sands JM -
Cell surface UT-A1 is sequestered in lipid rafts and phosphorylated and ubiquitinated in non-raft membrane domains
FASEB JOURNAL Volume: 23
04/01/2009 Authors: Feng X; Yang Y; Froehlich O; Klein JD; Sands JM; Chen G -
Urea and NaCl regulate UT-A1 urea transporter in opposing directions via TonEBP pathway during osmotic diuresis.
Am J Physiol Renal Physiol Volume: 296 Page(s): F67 - F77
01/01/2009 Authors: Kim Y-M; Kim W-Y; Lee H-W; Kim J; Kwon HM; Klein JD; Sands JM; Kim D -
Vasopressin in the Kidney: Historical Aspects
Page(s): 205 - 223
01/01/2009 Authors: Schlanger LE; Sands JM -
Candesartan Differentially Regulates Epithelial Sodium Channel in Cortex Versus Medulla of Streptozotocin-Induced Diabetic Rats.
J Epithel Biol Pharmacol Volume: 2 Page(s): 23
01/01/2009 Authors: Klein JD; Rash A; Sands JM; Ecelbarger CM; Tiwari S -
Potential role of purinergic signaling in urinary concentration in inner medulla: insights from P2Y2 receptor gene knockout mice.
Volume: 295 Page(s): F1715 - F1724
12/01/2008 Authors: Zhang Y; Sands JM; Kohan DE; Nelson RD; Martin CF; Carlson NG; Kamerath CD; Ge Y; Klein JD; Kishore BK -
MDM2 E3 ubiquitin ligase mediates UT-A1 urea transporter ubiquitination and degradation.
Am J Physiol Renal Physiol Volume: 295 Page(s): F1528 - F1534
11/01/2008 Authors: Chen G; Huang H; Frhlich O; Yang Y; Klein JD; Price SR; Sands JM -
Urea transporters UT-A1 and UT-A3 accumulate in the plasma membrane in response to increased hypertonicity.
Am J Physiol Renal Physiol Volume: 295 Page(s): F1336 - F1341
11/01/2008 Authors: Blessing NW; Blount MA; Sands JM; Martin CF; Klein JD -
Phosphorylation of the UT-A1 by PKA at serines 486 and 499 is important to vasopressin regulation of urea transport
Volume: 52 Page(s): E70 - E70
10/01/2008 Authors: Blount MA; Mistry AC; Froehlich O; Chen G; Sands JM; Klein JD -
Phosphorylation of UT-A1 urea transporter at serines 486 and 499 is important for vasopressin-regulated activity and membrane accumulation.
Am J Physiol Renal Physiol Volume: 295 Page(s): F295 - F299
07/01/2008 Authors: Blount MA; Mistry AC; Frhlich O; Price SR; Chen G; Sands JM; Klein JD -
Candesartan augments compensatory changes in medullary transport proteins in the diabetic rat kidney.
Am J Physiol Renal Physiol Volume: 294 Page(s): F1448 - F1452
06/01/2008 Authors: Blount MA; Sands JM; Kent KJ; Smith TD; Price SR; Klein JD -
AVP causes transient formation of cAMP and activation of phosphodiesterase activity in MDCK cells
FASEB JOURNAL Volume: 22
04/01/2008 Authors: Froehlich O; Blount MA; Yang Y; Klein JD; Sands JM -
Dynamin regulates UT-A1 urea transporter membrane expression
FASEB JOURNAL Volume: 22
04/01/2008 Authors: Huang H; Zhuang J; Froehlich O; Yang Y; Klein JD; Cai H; Sands JM; Chen G -
UT-A1 urea transporter activation does not involve furin-dependent cleavage
FASEB JOURNAL Volume: 22
04/01/2008 Authors: Huang H; Yang Y; Sands JM; Chen G -
Transport proteins in the inner medullas of diabetic kidneys are further increased by candesartan
FASEB JOURNAL Volume: 22
04/01/2008 Authors: Blount MA; Sands JM; Kent KJ; Smith TD; Klein JD -
Amiloride restores renal medullary osmolytes in lithium-induced nephrogenic diabetes insipidus.
Am J Physiol Renal Physiol Volume: 294 Page(s): F812 - F820
04/01/2008 Authors: Bedford JJ; Leader JP; Jing R; Walker LJ; Klein JD; Sands JM; Walker RJ -
Stimulation of UT-A1-mediated transepithelial urea flux in MDCK cells by lithium.
Am J Physiol Renal Physiol Volume: 294 Page(s): F518 - F524
03/01/2008 Authors: Frhlich O; Aggarwal D; Klein JD; Kent KJ; Yang Y; Gunn RB; Sands JM -
Candesartan augments the compensatory changes in medullary transport proteins in the diabetic rat kidney
Volume: 56 Page(s): 452 - 452
01/01/2008 Authors: Blount MA; Sands JM; Kent KJ; Smith TD; Klein JD -
The UT-A1 urea transporter interacts with snapin, a SNARE-associated protein.
J Biol Chem Volume: 282 Page(s): 30097 - 30106
10/12/2007 Authors: Mistry AC; Mallick R; Frhlich O; Klein JD; Rehm A; Chen G; Sands JM -
Forskolin stimulates phosphorylation and membrane accumulation of UT-A3.
Am J Physiol Renal Physiol Volume: 293 Page(s): F1308 - F1313
10/01/2007 Authors: Blount MA; Klein JD; Martin CF; Tchapyjnikov D; Sands JM -
Downregulation of renal TonEBP in hypokalemic rats.
Am J Physiol Renal Physiol Volume: 293 Page(s): F408 - F415
07/01/2007 Authors: Jeon US; Han K-H; Park S-H; Lee SD; Sheen MR; Jung J-Y; Kim WY; Sands JM; Kim J; Kwon HM -
The apical membrane is the rate-determining barrier for vasopressin-regulated trans-epithelial urea transport in MDCK-UTA1 cells
Volume: 21 Page(s): A906 - A906
04/01/2007 Authors: Froehlich O; Yang Y; Klein JD; Sands JM -
Increased urinary concentrating ability of P2Y2 receptor null mice is associated with marked increase in protein abundances of AQP2 and UT-A in renal medulla
Volume: 21 Page(s): A905 - A905
04/01/2007 Authors: Kishore BK; Sands JM; Kohan DE; Martin CF; Ge Y; Nelson RD; Klein JD -
Candesartan differentially regulates distal sodium transporters and channel subunits in cortex versus medulla in streptozotocin-induced diabetic rats.
Volume: 21 Page(s): A1331 - A1331
04/01/2007 Authors: Tiwari S; Halagappa VKM; Klein JD; Sands JM; Ecelbarger CA -
cAMP/adenylyl cyclase stimulation promotes 14-3-3 binding to UT-A1 urea transporter
Volume: 21 Page(s): A906 - A906
04/01/2007 Authors: Chen G; Li Z; Klein JD; Yang Y; Frhlich O; Du Y; Fu H; Sands JM -
UT-A3: is it an apical or basolateral membrane urea transporter?
Volume: 21 Page(s): A906 - A907
04/01/2007 Authors: Blount MA; Sands JM; Martin CF; Klein JD -
The role of SNARE proteins in trafficking and function of Urea Transporter UT-A1
Volume: 21 Page(s): A906 - A906
04/01/2007 Authors: Mistry AC; Mallick R; Klein JD; Froehlich O; Weimbs T; Chen G; Sands JM -
Critical role of urea in the urine-concentrating mechanism.
J Am Soc Nephrol Volume: 18 Page(s): 670 - 671
03/01/2007 Authors: Sands JM -
Significance of urea transport: the pioneering studies of Bodil Schmidt-Nielsen.
Am J Physiol Renal Physiol Volume: 291 Page(s): F1109 - F1112
12/01/2006 Authors: Kokko JP; Sands JM -
Urea transporter UT-A1 and aquaporin-2 proteins decrease in response to angiotensin II or norepinephrine-induced acute hypertension.
Am J Physiol Renal Physiol Volume: 291 Page(s): F952 - F959
11/01/2006 Authors: Klein JD; Murrell BP; Tucker S; Kim Y-H; Sands JM -
Vasopressin increases plasma membrane accumulation of urea transporter UT-A1 in rat inner medullary collecting ducts.
J Am Soc Nephrol Volume: 17 Page(s): 2680 - 2686
10/01/2006 Authors: Klein JD; Frhlich O; Blount MA; Martin CF; Smith TD; Sands JM -
Regulation of UT-A1-mediated transepithelial urea flux in MDCK cells.
Am J Physiol Cell Physiol Volume: 291 Page(s): C600 - C606
10/01/2006 Authors: Frhlich O; Klein JD; Smith PM; Sands JM; Gunn RB -
Loss of N-linked glycosylation reduces urea transporter UT-A1 response to vasopressin.
J Biol Chem Volume: 281 Page(s): 27436 - 27442
09/15/2006 Authors: Chen G; Frhlich O; Yang Y; Klein JD; Sands JM -
Effects of water restriction on gene expression in mouse renal medulla: identification of 3betaHSD4 as a collecting duct protein.
Am J Physiol Renal Physiol Volume: 291 Page(s): F218 - F224
07/01/2006 Authors: Cai Q; Keck M; McReynolds MR; Klein JD; Greer K; Sharma K; Hoying JB; Sands JM; Brooks HL -
Genetic restoration of aldose reductase to the collecting tubules restores maturation of the urine concentrating mechanism.
Am J Physiol Renal Physiol Volume: 291 Page(s): F186 - F195
07/01/2006 Authors: Yang JY; Tam WY; Tam S; Guo H; Wu X; Li G; Chau JFL; Klein JD; Chung SK; Sands JM -
Changes in subcellular distribution of the ammonia transporter, Rhcg, in response to chronic metabolic acidosis.
Am J Physiol Renal Physiol Volume: 290 Page(s): F1443 - F1452
06/01/2006 Authors: Seshadri RM; Klein JD; Smith T; Sands JM; Handlogten ME; Verlander JW; Weiner ID -
Tissue distribution of UT-A and UT-B mRNA and protein in rat.
Am J Physiol Regul Integr Comp Physiol Volume: 290 Page(s): R1446 - R1459
05/01/2006 Authors: Doran JJ; Klein JD; Kim YH; Smith TD; Kozlowski SD; Gunn RB; Sands JM -
Ubiquitination regulates urea transporter UT-A1 cell membrane expression
Volume: 20 Page(s): A1218 - A1218
03/07/2006 Authors: Chen GP; Frohlich OO; Mistry AC; Yang Y; Klein JD; Price SR; Sands JM -
Vasopressin increases plasma membrane accumulation of the UT-A1 urea transporter in rat inner medullary collecting ducts
Volume: 20 Page(s): A1218 - A1218
03/07/2006 Authors: Klein JD; Froehlich O; Smith TD; Sands JM -
Nephrogenic diabetes insipidus.
Ann Intern Med Volume: 144 Page(s): 186 - 194
02/07/2006 Authors: Sands JM; Bichet DG; American College of Physicians; American Physiological Society -
Ultrastructural localization of UT-A and UT-B in rat kidneys with different hydration status.
Volume: 290 Page(s): R479 - R492
02/01/2006 Authors: Lim S-W; Han K-H; Jung J-Y; Kim W-Y; Yang C-W; Sands JM; Knepper MA; Madsen KM; Kim J -
Renal expression of the ammonia transporters, Rhbg and Rhcg, in response to chronic metabolic acidosis.
Am J Physiol Renal Physiol Volume: 290 Page(s): F397 - F408
02/01/2006 Authors: Seshadri RM; Klein JD; Kozlowski S; Sands JM; Kim Y-H; Han K-H; Handlogten ME; Verlander JW; Weiner ID -
Down-regulation of the urea transporter UT-A1 by mineralocorticoids in the diabetic kidney.
Volume: 54 Page(s): S311 - S311
01/01/2006 Authors: Antoun TA; Sands JM; Klein JD -
Adrenalectomy blocks the compensatory increases in UT-A1 and AQP2 in diabetic rat kidney.
J Membr Biol Volume: 212 Page(s): 139 - 144
01/01/2006 Authors: Klein JD; Kozlowski S; Antoun TA; Sands JM -
Vasopressin increases urea permeability in the initial IMCD from diabetic rats.
Am J Physiol Renal Physiol Volume: 289 Page(s): F531 - F535
09/01/2005 Authors: Pech V; Klein JD; Kozlowski SD; Wall SM; Sands JM -
Regulated expression of renal and intestinal UT-B urea transporter in response to varying urea load.
Am J Physiol Renal Physiol Volume: 289 Page(s): F451 - F458
08/01/2005 Authors: Inoue H; Kozlowski SD; Klein JD; Bailey JL; Sands JM; Bagnasco SM -
ALDOSE REDUCTASE PROTECTS RENAL COLLECTING TUBULE EPITHELIAL CELLS FROM HYPEROSMOLALITY-INDUCED DNA DAMAGE
NEPHROLOGY Volume: 10 Page(s): A344 - A344
06/01/2005 Authors: Tam WY; Yang JY; Li GH; Guo H; Wu XC; Chau FL; Tam S; Chung SK; Klein JD; Sands JM -
Vasopressin increases urea permeability in initial IMCDs from diabetic rats
Volume: 19 Page(s): A587 - A587
03/04/2005 Authors: Pech V; Kozlowski SD; Klein JD; Wall SM; Sands JM -
Rab14 GTPase interacts with UT-A1 C-terminus: possible role as a regulatory factor of urea transporter activity
Volume: 19 Page(s): A589 - A589
03/04/2005 Authors: Chen GP; Gunn RB; Frohlich O; Yang Y; Klein JD; Smith PM; Sands JM -
Vasopressin activates urea transport by non-PKA mediated pathways
Volume: 19 Page(s): A589 - A590
03/04/2005 Authors: Frohlich O; Klein JD; Sands JM; Gunn RB -
Lithium activates urea transport in UT-A1-expressing MDCK cells
Volume: 19 Page(s): A589 - A589
03/04/2005 Authors: Aggarwal D; Gunn RB; Klein JD; Sands JM; Frohlich O -
A novel type of urea transporter, UT-C, is highly expressed in proximal tubule of seawater eel kidney.
Am J Physiol Renal Physiol Volume: 288 Page(s): F455 - F465
03/01/2005 Authors: Mistry AC; Chen G; Kato A; Nag K; Sands JM; Hirose S -
Urea may regulate urea transporter protein abundance during osmotic diuresis.
Am J Physiol Renal Physiol Volume: 288 Page(s): F188 - F197
01/01/2005 Authors: Kim D; Klein JD; Racine S; Murrell BP; Sands JM -
Micropuncture: unlocking the secrets of renal function.
Am J Physiol Renal Physiol Volume: 287 Page(s): F866 - F867
11/01/2004 Authors: Sands JM -
Renal urea transporters.
Curr Opin Nephrol Hypertens Volume: 13 Page(s): 525 - 532
09/01/2004 Authors: Sands JM -
Long-term treatment with cyclosporine decreases aquaporins and urea transporters in the rat kidney.
Volume: 287 Page(s): F139 - F151
07/01/2004 Authors: Lim S-W; Li C; Sun B-K; Han K-H; Kim W-Y; Oh Y-W; Lee J-U; Kador PF; Knepper MA; Sands JM -
Altered expression of urea transporters in response to ureteral obstruction.
Am J Physiol Renal Physiol Volume: 286 Page(s): F1154 - F1162
06/01/2004 Authors: Li C; Klein JD; Wang W; Knepper MA; Nielsen S; Sands JM; Frkiaer J -
Urea transport in MDCK cells that are stably transfected with UT-A1.
Am J Physiol Cell Physiol Volume: 286 Page(s): C1264 - C1270
06/01/2004 Authors: Frhlich O; Klein JD; Smith PM; Sands JM; Gunn RB -
Upregulation of urea transporter UT-A2 and water channels AQP2 and AQP3 in mice lacking urea transporter UT-B.
J Am Soc Nephrol Volume: 15 Page(s): 1161 - 1167
05/01/2004 Authors: Klein JD; Sands JM; Qian L; Wang X; Yang B -
Effect of nitrogen intake on nitrogen recycling and urea transporter abundance in lambs.
J Anim Sci Volume: 82 Page(s): 1157 - 1164
04/01/2004 Authors: Marini JC; Klein JD; Sands JM; Van Amburgh ME -
Role of vasopressin in diabetes mellitus-induced changes in medullary transport proteins involved in urine concentration in Brattleboro rats.
Am J Physiol Renal Physiol Volume: 286 Page(s): F760 - F766
04/01/2004 Authors: Kim D; Sands JM; Klein JD -
UT-A1 is expressed in the apical membrane of stably transfected MDCK cells
Volume: 18 Page(s): A1019 - A1019
03/24/2004 Authors: Klein JD; Froehlich O; Smith PM; Gunn RB; Sands JM -
Quantitative measurements of the electroneutral Na/bicarbonate cotransporter (NBCn1) expression in chronic metabolic acidosis
Volume: 18 Page(s): A1018 - A1018
03/24/2004 Authors: Cucoranu D; Cooper DS; Shyntum DY; Chen GP; Klein JD; Sands JM; Choi I -
Upregulation of urea transporter UT-A2 and water channels AQP2 and AQP3 in transgenic mice lacking urea transporter UT-B
Volume: 18 Page(s): A1018 - A1018
03/24/2004 Authors: Yang BX; Sands JM; Qian LM; Wang XD; Klein JD -
Aldosterone decreases UT-A1 urea transporter expression via the mineralocorticoid receptor.
J Am Soc Nephrol Volume: 15 Page(s): 558 - 565
03/01/2004 Authors: Gertner RA; Klein JD; Bailey JL; Kim D-U; Luo XH; Bagnasco SM; Sands JM -
Expression of urea transporters in potassium-depleted mouse kidney.
Am J Physiol Renal Physiol Volume: 285 Page(s): F1210 - F1224
12/01/2003 Authors: Jung J-Y; Madsen KM; Han K-H; Yang C-W; Knepper MA; Sands JM; Kim J -
Urea inhibits UT-A mRNA expression.
Volume: 14 Page(s): 75A - 75A
11/01/2003 Authors: Inoue H; Vikulina T; Peng T; Klein J; Sands JM; Bagnasco SM -
The N-glycosylation site in the second large extracellular loop of UT-A1 is critical for its urea transport properties.
Volume: 14 Page(s): 74A - 74A
11/01/2003 Authors: Chen GP; Gunn RB; Froehlich O; Choi IY; Sands JM -
Long-term treatment of cyclosporine decreases aquaporins and urea transporters: The possible mechanism of urine concentration.
Volume: 14 Page(s): 76A - 76A
11/01/2003 Authors: Lim SW; Li C; Sun BK; Yang CW; Kim YS; Knepper MA; Sands JM; Kim J; Bang BK -
Urine urea may regulate the abundance of the UT-A1 urea transporter during osmotic diuresis.
Volume: 14 Page(s): 74A - 75A
11/01/2003 Authors: Kim D; Klein JD; Sands JM -
Glucocorticoids and mineralocorticoids decrease UT-A1 abundance by different pathways.
Volume: 14 Page(s): 74A - 74A
11/01/2003 Authors: Gertner RA; Klein JD; Kim D; Bailey JL; Sands JM -
Urea transport may be regulated by phosphorylation of UT-A1 in stably transfected MDCK cells.
Volume: 14 Page(s): 74A - 74A
11/01/2003 Authors: Klein JD; Frohlich O; Smith PM; Bagnasco SM; Gunn RB; Sands JM -
Immunohistochemical localization of urea transporters A and B in the rat cochlea.
Hear Res Volume: 183 Page(s): 84 - 96
09/01/2003 Authors: Kwun Y-S; Yeo SW; Ahn Y-H; Lim S-W; Jung J-Y; Kim W-Y; Sands JM; Kim J -
Changes in renal medullary transport proteins during uncontrolled diabetes mellitus in rats.
Am J Physiol Renal Physiol Volume: 285 Page(s): F303 - F309
08/01/2003 Authors: Kim D; Sands JM; Klein JD -
Transport of urea across epithelial membranes of MDCK cells expressing UT-A1
Volume: 122 Page(s): 43A - 43A
07/01/2003 Authors: Gunn RB; Froehlich OA; Smith PM; Klein JD; Bagnasco SM; Sands JM -
Urine-concentrating ability in the aging kidney.
Sci Aging Knowledge Environ Volume: 2003 Page(s): PE15
06/18/2003 Authors: Sands JM -
UT-A1 is up-regulated by both Diabetes metlitus and vasopressin in the Brattleboro rat
Volume: 17 Page(s): A484 - A484
03/14/2003 Authors: Kim D; Sands JM; Gertner RA; Klein JD -
UT-A abundance is increased in rat kidney cortex by a low protein diet
Volume: 17 Page(s): A484 - A484
03/14/2003 Authors: Klein JD; Doran JJ; Sands JM -
Molecular mechanisms of urea transport.
J Membr Biol Volume: 191 Page(s): 149 - 163
02/01/2003 Authors: Sands JM -
Aldosterone decreases urea transporter protein in the inner medulla of adrenalectomized rats.
Volume: 51 Page(s): S295 - S295
02/01/2003 Authors: Gertner RA; Klein JD; Bailey JL; Sands JM -
Aldosterone decreases urea transporter protein in the inner medulla of adrenalectomized rats.
Volume: 51 Page(s): S273 - S274
02/01/2003 Authors: Gertner RA; Klein JD; Bailey JL; Sands JM -
AJP-Renal is doing great, but we can still do better with your help!
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY Volume: 284 Page(s): F1 - F1
01/01/2003 Authors: Sands JM -
Mammalian urea transporters.
Annu Rev Physiol Volume: 65 Page(s): 543 - 566
01/01/2003 Authors: Sands JM -
Molecular approaches to urea transporters.
J Am Soc Nephrol Volume: 13 Page(s): 2795 - 2806
11/01/2002 Authors: Sands JM -
Hydration status affects subcellular localization of UT-A and UT-B in rat kidney.
Volume: 13 Page(s): 68A - 68A
09/01/2002 Authors: Lim SW; Kim YH; Lee BS; Cha JH; Sands JM; Knepper MA; Madsen KM; Kim J -
Urea transporters are distributed in endothelial cells and mediate inhibition of L-arginine transport.
Am J Physiol Renal Physiol Volume: 283 Page(s): F578 - F582
09/01/2002 Authors: Wagner L; Klein JD; Sands JM; Baylis C -
Regulation of renal transporter abundances in diabetic rats.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 13 Page(s): 67A - 67A
09/01/2002 Authors: Kim DU; Klein JD; Meireles CL; Sands JM -
Expression of urea transporters in hypokalemic mouse kidney.
Volume: 13 Page(s): 68A - 68A
09/01/2002 Authors: Jung JY; Lim SW; Kim WY; Han KH; Cha JH; Knepper MA; Sands JM; Madsen KM; Kim J -
Aldosterone decreases UT-A1 urea transporter in the rat inner medulla.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 13 Page(s): 69A - 69A
09/01/2002 Authors: Klein JD; Luo XH; Wang XD; Reyes MI; Sands JM -
Impaired urine concentration and absence of tissue ACE: involvement of medullary transport proteins.
Am J Physiol Renal Physiol Volume: 283 Page(s): F517 - F524
09/01/2002 Authors: Klein JD; Le Quach D; Cole JM; Disher K; Mongiu AK; Wang X; Bernstein KE; Sands JM -
Glucocorticoids inhibit transcription and expression of the UT-A urea transporter gene.
Am J Physiol Renal Physiol Volume: 282 Page(s): F853 - F858
05/01/2002 Authors: Peng T; Sands JM; Bagnasco SM -
Aldosterone decreases the abundance of the UT-A1 urea transporter in the rat inner medulla.
FASEB JOURNAL Volume: 16 Page(s): A890 - A890
03/22/2002 Authors: Luo XH; Klein JD; Reyes MI; Sands JM -
Altered expression of urea transporters in rat kidneys in response to urinary tract obstruction.
FASEB JOURNAL Volume: 16 Page(s): A843 - A843
03/22/2002 Authors: Li CL; Klein JD; Wang WD; Knepper MA; Nielsen S; Sands JM; Frokiaer J -
Renal UT-A mRNA expression in metabolic acidosis.
FASEB JOURNAL Volume: 16 Page(s): A52 - A52
03/20/2002 Authors: Bagnasco SM; Klaavuniemi T; Vikulina T; Deel MJ; Sands JM; Klein JD -
The urine concentrating defect in ACE.2 mice results from alterations in solute transport.
FASEB JOURNAL Volume: 16 Page(s): A51 - A51
03/20/2002 Authors: Klein JD; Le Quach D; Cole JM; Disher K; Mongiu A; Bernstein KE; Sands JM -
Down-regulation of urea transporters in the renal inner medulla of lithium-fed rats.
Kidney Int Volume: 61 Page(s): 995 - 1002
03/01/2002 Authors: Klein JD; Gunn RB; Roberts BR; Sands JM -
Expression of urea transporters in the developing rat kidney.
Volume: 282 Page(s): F530 - F540
03/01/2002 Authors: Kim Y-H; Kim D-U; Han K-H; Jung J-Y; Sands JM; Knepper MA; Madsen KM; Kim J -
Acidosis mediates the upregulation of UT-A protein in livers from uremic rats.
J Am Soc Nephrol Volume: 13 Page(s): 581 - 587
03/01/2002 Authors: Klein JD; Rouillard P; Roberts BR; Sands JM -
Vasopressin rapidly increases phosphorylation of UT-A1 urea transporter in rat IMCDs through PKA.
Am J Physiol Renal Physiol Volume: 282 Page(s): F85 - F90
01/01/2002 Authors: Zhang C; Sands JM; Klein JD -
A prospective evaluation of the glomerular filtration rate in older adults with frequent nighttime urination.
J Urol Volume: 167 Page(s): 146 - 150
01/01/2002 Authors: Johnson TM; Sands JM; Ouslander JG -
Urine concentrating mechanism: Measured permeability values in medullary nephron segments and urea transport processes
Volume: 129 Page(s): 193 - 210
01/01/2002 Authors: Sands JM -
Expression of salt and urea transporters in rat kidney during cisplatin-induced polyuria.
Volume: 60 Page(s): 2274 - 2282
12/01/2001 Authors: Ecelbarger CA; Sands JM; Doran JJ; Cacini W; Kishore BK -
Localization of the urea transporter UT-B protein in human and rat erythrocytes and tissues.
Am J Physiol Cell Physiol Volume: 281 Page(s): C1318 - C1325
10/01/2001 Authors: Timmer RT; Klein JD; Bagnasco SM; Doran JJ; Verlander JW; Gunn RB; Sands JM -
Cloning and characterization of the human urea transporter UT-A1 and mapping of the human Slc14a2 gene.
Am J Physiol Renal Physiol Volume: 281 Page(s): F400 - F406
09/01/2001 Authors: Bagnasco SM; Peng T; Janech MG; Karakashian A; Sands JM -
UT-A urea transporter protein in heart: increased abundance during uremia, hypertension, and heart failure.
Circ Res Volume: 89 Page(s): 139 - 145
07/20/2001 Authors: Duchesne R; Klein JD; Velotta JB; Doran JJ; Rouillard P; Roberts BR; McDonough AA; Sands JM -
97- and 117-kDa forms of collecting duct urea transporter UT-A1 are due to different states of glycosylation.
Am J Physiol Renal Physiol Volume: 281 Page(s): F133 - F143
07/01/2001 Authors: Bradford AD; Terris JM; Ecelbarger CA; Klein JD; Sands JM; Chou CL; Knepper MA -
Urea excretion in white rats and kangaroo rats as influenced by excitement and by diet - Commentary
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 12 Page(s): 859 - 862
04/01/2001 Authors: Sands JM -
Urea excretion in white rats and kangaroo rats as influenced by excitement and by diet.
J Am Soc Nephrol Volume: 12 Page(s): 856 - 864
04/01/2001 -
Cloning of the rat Slc14a2 gene and genomic organization of the UT-A urea transporter.
Biochim Biophys Acta Volume: 1518 Page(s): 19 - 26
03/19/2001 Authors: Nakayama Y; Naruse M; Karakashian A; Peng T; Sands JM; Bagnasco SM -
Up-regulation of UT-A urea transporters in human heart failure.
FASEB JOURNAL Volume: 15 Page(s): A852 - A852
03/08/2001 Authors: Velotta JB; Sands JM; McDonough AA -
UT-A1 urea transporter regulation in lithium-treated rats.
FASEB JOURNAL Volume: 15 Page(s): A852 - A852
03/08/2001 Authors: Roberts BR; Klein JD; Gunn RB; Sands JM -
Phosphorylation acutely regulates UT-A1 urea transporter activity in both rat tubules and cultured cells.
FASEB JOURNAL Volume: 15 Page(s): A853 - A853
03/08/2001 Authors: Klein JD; Froehlich O; Zhang C; Timmer RT; Gunn RB; Sands JM -
The TonE/TonEBP pathway mediates tonicity-responsive regulation of UT-A urea transporter expression.
J Biol Chem Volume: 275 Page(s): 38275 - 38280
12/08/2000 Authors: Nakayama Y; Peng T; Sands JM; Bagnasco SM -
Differential expression of individual UT-A urea transporter isoforms in rat kidney.
J Am Soc Nephrol Volume: 11 Page(s): 1980 - 1986
11/01/2000 Authors: Bagnasco SM; Peng T; Nakayama Y; Sands JM -
Angiotensin II increases vasopressin-stimulated facilitated urea permeability in rat terminal IMCDs.
Am J Physiol Renal Physiol Volume: 279 Page(s): F835 - F840
11/01/2000 Authors: Kato A; Klein JD; Zhang C; Sands JM -
Renal function in geriatric patients with nocturia and nocturnal polyuria
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY Volume: 48 Page(s): S52 - S52
08/01/2000 Authors: Johnson T; Sands J; Cooper E; Godley D; Ouslander J -
Glucocorticoids alter UT-A urea transporter protein abundances in the kidney.
FASEB JOURNAL Volume: 14 Page(s): A347 - A347
03/15/2000 Authors: Klein JD; Rouillard P; Bailey JL; Sands JM -
TonE sequences mediate increased transcription of UT-A1, UT-A3, and UT-A4 in response to hypertonicity.
FASEB JOURNAL Volume: 14 Page(s): A348 - A348
03/15/2000 Authors: Nakayama Y; Peng T; Sands JM; Bagnasco SM -
Differential response of UT-A glycoproteins to acidosis.
FASEB JOURNAL Volume: 14 Page(s): A347 - A347
03/15/2000 Authors: Klein JD; Rouillard P; Duchesne R; Sands JM -
Regulation of urea transporter proteins in kidney and liver.
Mt Sinai J Med Volume: 67 Page(s): 112 - 119
03/01/2000 Authors: Sands JM -
Differential response of UT-A glycoproteins to acidosis.
JOURNAL OF INVESTIGATIVE MEDICINE Volume: 48 Page(s): 192A - 192A
03/01/2000 Authors: Klein JD; Rouillard P; Duchesne R; Sands JM -
Glucocorticoids alter UT-A urea transporter protein abundances in the kidney.
JOURNAL OF INVESTIGATIVE MEDICINE Volume: 48 Page(s): 192A - 192A
03/01/2000 Authors: Klein JD; Rouillard P; Bailey JL; Sands JM -
Effect of age and testosterone on the vasopressin and aquaporin responses to dehydration in Fischer 344/Brown-Norway F1 rats.
J Gerontol A Biol Sci Med Sci Volume: 55 Page(s): B26 - B34
01/01/2000 Authors: Catudioc-Vallero J; Sands JM; Klein JD; Sidorowicz HE; Sladek CD -
UT-A urea transporter protein expressed in liver: upregulation by uremia.
J Am Soc Nephrol Volume: 10 Page(s): 2076 - 2083
10/01/1999 Authors: Klein JD; Timmer RT; Rouillard P; Bailey JL; Sands JM -
Accurate mRNA size determination in northern analysis using individual lane size markers.
Biotechniques Volume: 27 Page(s): 280 - 282
08/01/1999 Authors: Doran JJ; Sands JM; Timmer RT -
The medullary collecting duct urea transporters.
Curr Opin Nephrol Hypertens Volume: 8 Page(s): 499 - 504
07/01/1999 Authors: Sands JM -
The erythrocyte urea transporter UT-B protein is expressed in rat kidney, liver, and heart.
JOURNAL OF INVESTIGATIVE MEDICINE Volume: 47 Page(s): 211A - 211A
04/01/1999 Authors: Timmer RT; Verlander JW; Bagnasco SM; Rouillard P; Klein JD; Stockman B; Sands JM; Gunn RB -
UT-A urea transporter proteins in rat heart: Regulation by uremia and angiotensin II.
JOURNAL OF INVESTIGATIVE MEDICINE Volume: 47 Page(s): 187A - 187A
04/01/1999 Authors: Duchesne R; Klein JD; Rouillard P; Bailey JL; Lea JP; Sands JM -
Urea transporter mRNA isoforms are expressed in rat tissues and mammalian cell lines.
JOURNAL OF INVESTIGATIVE MEDICINE Volume: 47 Page(s): 187A - 187A
04/01/1999 Authors: Doran JJ; Sands JM; Gunn RB; Bagnasco SM; Timmer RT -
Long-term regulation of UT-A isoforms expression in mIMCD3 cells.
JOURNAL OF INVESTIGATIVE MEDICINE Volume: 47 Page(s): 204A - 204A
04/01/1999 Authors: Nakayama Y; Karakashian A; Peng T; Rouillard P; Sands JM; Bagnasco SM -
UT-A urea transporter proteins in rat heart: Regulation by uremia and angiotensin II.
FASEB JOURNAL Volume: 13 Page(s): A392 - A392
03/12/1999 Authors: Duchesne R; Klein JD; Rouillard P; Bailey JL; Lea JP; Sands JM -
Long-term regulation of UT-A isoforms expression in mIMCD3 cells.
FASEB JOURNAL Volume: 13 Page(s): A391 - A391
03/12/1999 Authors: Nakayama Y; Karakashian A; Peng T; Rouillard P; Sands JM; Bagnasco SM -
The erythrocyte urea transporter UT-B protein is expressed in rat kidney, liver, and heart
FASEB JOURNAL Volume: 13 Page(s): A391 - A391
03/12/1999 Authors: Timmer RT; Verlander JW; Bagnasco SM; Rouillard P; Klein JD; Stockman B; Sands JM; Gunn RB -
Urea transporter mRNA isoforms are expressed in rat tissues and mammalian cell lines.
FASEB JOURNAL Volume: 13 Page(s): A392 - A392
03/12/1999 Authors: Doran JJ; Sands JM; Gunn RB; Bagnasco SM; Timmer RT -
Regulation of renal urea transporters.
J Am Soc Nephrol Volume: 10 Page(s): 635 - 646
03/01/1999 Authors: Sands JM -
Lithium intoxication.
J Am Soc Nephrol Volume: 10 Page(s): 666 - 674
03/01/1999 Authors: Timmer RT; Sands JM -
Cloning and characterization of two new isoforms of the rat kidney urea transporter: UT-A3 and UT-A4.
J Am Soc Nephrol Volume: 10 Page(s): 230 - 237
02/01/1999 Authors: Karakashian A; Timmer RT; Klein JD; Gunn RB; Sands JM; Bagnasco SM -
Urea Transport: It's Not Just "Freely Diffusible" Anymore.
News Physiol Sci Volume: 14 Page(s): 46 - 47
02/01/1999 Authors: Sands JM -
Urea transport processes are induced in rat IMCD subsegments when urine concentrating ability is reduced.
Am J Physiol Volume: 276 Page(s): F62 - F71
01/01/1999 Authors: Kato A; Sands JM -
Immunolocalization of phospholipase C isoforms in rat kidney.
Kidney Int Volume: 54 Page(s): 1484 - 1490
11/01/1998 Authors: Lea JP; Ertoy D; Hollis JL; Marrero MB; Sands JM -
Active sodium-urea counter-transport is inducible in the basolateral membrane of rat renal initial inner medullary collecting ducts.
J Clin Invest Volume: 102 Page(s): 1008 - 1015
09/01/1998 Authors: Kato A; Sands JM -
Long-term regulation of inner medullary collecting duct urea transport in rat.
J Am Soc Nephrol Volume: 9 Page(s): 737 - 745
05/01/1998 Authors: Kato A; Naruse M; Knepper MA; Sands JM -
Vasopressin-elicited water and urea permeabilities are altered in IMCD in hypercalcemic rats.
Am J Physiol Volume: 274 Page(s): F978 - F985
05/01/1998 Authors: Sands JM; Flores FX; Kato A; Baum MA; Brown EM; Ward DT; Hebert SC; Harris HW -
Long-term regulation of renal urea transporter protein expression in rat.
J Am Soc Nephrol Volume: 9 Page(s): 729 - 736
05/01/1998 Authors: Terris J; Ecelbarger CA; Sands JM; Knepper MA -
Abundance of UT-A urea transporter protein isoforms is altered in uremic rats.
FASEB JOURNAL Volume: 12 Page(s): A331 - A331
03/17/1998 Authors: Sands JM; Rouillard P; Bailey JL; Klein JD -
Two isoforms of the UT-A urea transporter are expressed in liver.
FASEB JOURNAL Volume: 12 Page(s): A423 - A423
03/17/1998 Authors: Klein JD; Rouillard P; Sands JM -
Furosemide induces active urea reabsorption in the IMCD1 and decreases active urea secretion in the IMCD3 in rat kidney.
FASEB JOURNAL Volume: 12 Page(s): A423 - A423
03/17/1998 Authors: Kato A; Sands JM -
Evidence for sodium-dependent active urea secretion in the deepest subsegment of the rat inner medullary collecting duct.
J Clin Invest Volume: 101 Page(s): 423 - 428
01/15/1998 Authors: Kato A; Sands JM -
Effect of age and testosterone on the vasopressin response to dehydration in F344BNF1 male rats.
Adv Exp Med Biol Volume: 449 Page(s): 183 - 185
01/01/1998 Authors: Catudioc-Vallero J; Sands JM; Sidorowicz HE; Klein JD; Sladek CD -
Glucocorticoids mediate a decrease in AVP-regulated urea transporter in diabetic rat inner medulla.
Am J Physiol Renal Physiol Volume: 273 Page(s): F949 - F953
12/01/1997 Authors: Klein JD; Price SR; Bailey JL; Jacobs JD; Sands JM -
Glucocorticoids mediate a decrease in AVP-regulated urea transporter in diabetic rat inner medulla.
Am J Physiol Volume: 273 Page(s): F949 - F953
12/01/1997 Authors: Klein JD; Price SR; Bailey JL; Jacobs JD; Sands JM -
Heterologous expression of the 2.9 and 4.0 kb isoforms of the rat renal urea transporter.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 8 Page(s): A0123 - A0123
09/01/1997 Authors: Timmer RT; Bagnasco SM; Karakashian A; Klein JD; Sands JM; Gunn RB -
Furosemide alters active urea reabsorption in rat initial IMCD.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 8 Page(s): A0090 - A0090
09/01/1997 Authors: Kato A; Sands JM -
Urea is actively secreted in the deepest portion of the rat IMCD.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 8 Page(s): A0091 - A0091
09/01/1997 Authors: Kato A; Sands JM -
The gene encoding the rat renal urea transporter (UT-A) has an internal promoter, which may control expression of UT-A2 (UT-2).
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 8 Page(s): A0107 - A0107
09/01/1997 Authors: Naruse M; Karakashian A; Nakayama Y; Sands JM; Bagnasco SM -
Identification of two new mRNA isoforms of the rat renal urea transporter (UT-A) gene.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 8 Page(s): A0070 - A0070
09/01/1997 Authors: Bagnasco SM; Karakashian A; Timmer RT; Klein JD; Sands JM -
Differential expression of the PLC-delta(1) isoform occurs in both human and rat models of hypertension.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 8 Page(s): A1392 - A1392
09/01/1997 Authors: Lea JP; Ertoy D; Marerro MB; Sands JM -
The vasopressin-regulated urea transporter is phosphorylated in rat inner medulla.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 8 Page(s): A0094 - A0094
09/01/1997 Authors: Klein JD; Rouillard P; Kato A; Sands JM -
Water diuresis increases active urea secretion in rat terminal IMCD subsegments.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 8 Page(s): A0092 - A0092
09/01/1997 Authors: Kato A; Sands JM -
Urea transporters in kidney and erythrocytes.
Am J Physiol Volume: 273 Page(s): F321 - F339
09/01/1997 Authors: Sands JM; Timmer RT; Gunn RB -
Effect of aging on vasopressin and aquaporin responses to dehydration in Fischer 344 Brown-Norway F1 rats
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY Volume: 273 Page(s): R35 - R40
07/01/1997 Authors: Swenson KL; Sands JM; Jacobs JD; Sladek CD -
Effect of aging on vasopressin and aquaporin responses to dehydration in Fischer 344-brown-Norway F1 rats.
Am J Physiol Volume: 273 Page(s): R35 - R40
07/01/1997 Authors: Swenson KL; Sands JM; Jacobs JD; Sladek CD -
Glucocorticoids downregulate the vasopressin-regulated urea transporter in rat terminal inner medullary collecting ducts.
J Am Soc Nephrol Volume: 8 Page(s): 517 - 523
04/01/1997 Authors: Naruse M; Klein JD; Ashkar ZM; Jacobs JD; Sands JM -
Apical extracellular calcium/polyvalent cation-sensing receptor regulates vasopressin-elicited water permeability in rat kidney inner medullary collecting duct.
J Clin Invest Volume: 99 Page(s): 1399 - 1405
03/15/1997 Authors: Sands JM; Naruse M; Baum M; Jo I; Hebert SC; Brown EM; Harris HW -
Bartter's syndrome, supraventricular tachycardia, mitral valve prolapse, and asthma: a therapeutic challenge.
Am J Med Sci Volume: 313 Page(s): 114 - 116
02/01/1997 Authors: Rodriguez DF; Kokko JP; Sands JM -
Heterologous expression and characterization of the 2.9 KB isoform of the rat renal urea transporter.
BIOPHYSICAL JOURNAL Volume: 72 Page(s): TH384 - TH384
02/01/1997 Authors: Timmer RT; Gunn RB; Froehlich O; Bagnasco SM; Klein JD; Sands JM -
Safety and efficacy of low-dose subcutaneous erythropoietin in hemodialysis patients.
J Am Soc Nephrol Volume: 8 Page(s): 288 - 293
02/01/1997 Authors: Parker KP; Mitch WE; Stivelman JC; Macon EJ; Bailey JL; Sands JM -
Transport of hydroxyurea in erythrocytes; Implications for hydroxyurea handling in the kidney.
BIOPHYSICAL JOURNAL Volume: 72 Page(s): TU338 - TU338
02/01/1997 Authors: Frohlich O; Timmer RT; Gunn RB; Sands J -
Current concepts of the countercurrent multiplication system.
Kidney Int Suppl Volume: 57 Page(s): S93 - S99
12/01/1996 Authors: Sands JM; Kokko JP -
Heterogeneity of facilitated urea transport in rat terminal IMCD following chronic changes in hydration state in vivo
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 7 Page(s): A0099 - A0099
09/01/1996 Authors: Kato A; Naruse M; Sands JM -
Rat facilitated urea transporter protein is decreased in the inner medullary tip of diabetic rats.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 7 Page(s): A0102 - A0102
09/01/1996 Authors: Klein JD; Price SR; Jacobs JD; Sands JM -
Regulation of vasopressin (AVP)-elicited water permeability (Pf) in rat kidney terminal inner medullary collecting duct (tIMCD) by an apical extracellular calcium-sensing receptor (CaR)
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 7 Page(s): A0096 - A0096
09/01/1996 Authors: Harris HW; Baum MA; Naruse M; Jo I; Hebert SC; Brown EM; Sands JM -
Glucocorticoids regulate the facilitated urea transporter protein and urea transport in rat terminal IMCDs.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 7 Page(s): A0112 - A0112
09/01/1996 Authors: Naruse M; Klein JD; Jacobs JD; Sands JM -
Angiotensin II receptor (AT(1)) signalling in LLC-PK1 renal epithelial cells occurs via tyrosine phosphorylation of phospholipase C gamma 1.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 7 Page(s): A2166 - A2166
09/01/1996 Authors: Lea JP; Sands JM; Bernstein KE; Marrero MB -
Aged rats do not increase aquaporin-2 protein in response to dehydration.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 7 Page(s): A0125 - A0125
09/01/1996 Authors: Sands JM; Swenson KL; Jacobs JD; Sladek CD -
Changes in aquaporin-2 protein contribute to the urine concentrating defect in rats fed a low-protein diet.
J Clin Invest Volume: 97 Page(s): 2807 - 2814
06/15/1996 Authors: Sands JM; Naruse M; Jacobs JD; Wilcox JN; Klein JD -
Active urea transport in the rat inner medullary collecting duct: functional characterization and initial expression cloning.
Kidney Int Volume: 49 Page(s): 1611 - 1614
06/01/1996 Authors: Sands JM; Martial S; Isozaki T -
Extracellular Ca2+ receptor
JOURNAL OF PHYSIOLOGY-LONDON Volume: 493P Page(s): S5 - S6
05/01/1996 Authors: Hebert SC; Brown E; Riccardi D; Harris W; Sands J; Wang WH -
EVIDENCE THAT CHANGES IN AQUAPORIN-2 PROTEIN MAY CONTRIBUTE TO THE URINE CONCENTRATING DEFECT IN RATS FED A LOW-PROTEIN DIET
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 6 Page(s): 329 - 329
09/01/1995 Authors: SANDS JM; JACOBS JD; WILCOX JN; KLEIN JD -
Cloning and regulation of expression of the rat kidney urea transporter (rUT2).
J Clin Invest Volume: 96 Page(s): 1556 - 1563
09/01/1995 Authors: Smith CP; Lee WS; Martial S; Knepper MA; You G; Sands JM; Hediger MA -
REGULATION OF THE RAT FACILITATED UREA TRANSPORTER - THE INFLUENCE OF GLUCOCORTICOIDS AND DIETARY-PROTEIN
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 6 Page(s): 319 - 319
09/01/1995 Authors: ASHKAR ZM; SANDS JM -
CAN THE ERYTHROPOIETIN DOSE BE LOWERED SAFELY - A CASE-CONTROL STUDY OF SUBCUTANEOUS ADMINISTRATION
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 6 Page(s): 556 - 556
09/01/1995 Authors: PARKER KP; LACOURSIERE T; MACON EJ; STIVELMAN JC; BAILEY JL; MITCH WE; SANDS JM -
MOLECULAR CHARACTERIZATION AND REGULATION OF EXPRESSION OF THE VASOPRESSIN-REGULATED UREA TRANSPORTER
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 6 Page(s): 329 - 329
09/01/1995 Authors: SMITH CP; SHAYAKUL C; YOU GF; MARTIAL S; LEE WS; MACKENZIE HS; SANDS JM; KNEPPER MA; HEDIGER MA -
Urea transport in initial IMCD of rats fed a low-protein diet: functional properties and mRNA abundance.
Am J Physiol Volume: 268 Page(s): F1218 - F1223
06/01/1995 Authors: Ashkar ZM; Martial S; Isozaki T; Price SR; Sands JM -
Regulation of aldose reductase, sorbitol dehydrogenase, and taurine cotransporter mRNA in rat medulla.
J Am Soc Nephrol Volume: 5 Page(s): 1971 - 1978
05/01/1995 Authors: Martial S; Price SR; Sands JM -
EFFECT OF A LOW-PROTEIN DIET ON UREA TRANSPORTER MESSENGER-RNA ABUNDANCE IN RAT INNER MEDULLARY REGIONS
FASEB JOURNAL Volume: 9 Page(s): A563 - A563
03/09/1995 Authors: MARTIAL S; ASHKAR ZM; SANDS JM -
ALDOSTERONE REGULATES CALCINEURIN PROTEIN EXPRESSION IN RAT CORTICAL COLLECTING DUCT
FASEB JOURNAL Volume: 9 Page(s): A564 - A564
03/09/1995 Authors: LEA JP; SOMEREN JT; SANDS JM; TUMLIN JA -
Regulation of kidney urea transporters by vasopressin and dietary protein
Volume: 1098 Page(s): 525 - 534
01/01/1995 Authors: Sands JM; Isozaki T; Ashkar ZM; Martial S; Price SR -
Sodium-dependent net urea transport in rat initial inner medullary collecting ducts.
J Clin Invest Volume: 94 Page(s): 1513 - 1517
10/01/1994 Authors: Isozaki T; Lea JP; Tumlin JA; Sands JM -
ALDOSTERONE STIMULATES CALCINEURIN ACTIVITY IN RAT DISTAL NEPHRON SEGMENTS
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 5 Page(s): 734 - 734
09/01/1994 Authors: TUMLIN JA; SANDS JM; LEA JP -
LOW-PROTEIN DIETS INDUCE SODIUM-DEPENDENT NET UREA TRANSPORT AND BLOCK AVP-STIMULATED WATER TRANSPORT IN RAT INITIAL IMCDA
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 5 Page(s): 273 - 273
09/01/1994 Authors: ISOZAKI T; SANDS JM -
WEEKLY SUBCUTANEOUS ERYTHROPOIETIN MAINTAINS HEMATOCRIT IN CHRONIC-HEMODIALYSIS PATIENTS
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 5 Page(s): 470 - 470
09/01/1994 Authors: PARKER KP; LACOURSIERE T; MACON EJ; STIVELMAN JC; BAILEY JL; KIKERI D; MITCH WE; SANDS JM -
REGULATION OF ALDOSE REDUCTASE, SORBITOL DEHYDROGENASE AND TAURINE COTRANSPORTER MESSENGER-RNAS BY URINE OSMOLALITY IN RAT INNER MEDULLA
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 5 Page(s): 314 - 314
09/01/1994 Authors: MARTIAL S; PRICE SR; SANDS JM -
CALCINEURIN ACTIVITY AND EXPRESSION OF ITS ALPHA-ISOFORM AND BETA-ISOFORM PROTEINS ARE HETEROGENEOUS ALONG THE RAT NEPHRON
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Volume: 5 Page(s): 721 - 721
09/01/1994 Authors: LEA JP; SANDS JM; TUMLIN JA -
Evidence that the inhibition of Na+/K(+)-ATPase activity by FK506 involves calcineurin.
Kidney Int Volume: 46 Page(s): 647 - 652
09/01/1994 Authors: Lea JP; Sands JM; McMahon SJ; Tumlin JA -
Protein restriction sequentially induces new urea transport processes in rat initial IMCD.
Am J Physiol Volume: 266 Page(s): F756 - F761
05/01/1994 Authors: Isozaki T; Gillin AG; Swanson CE; Sands JM -
SPECIFIC CELL BIOLOGIC RESPONSES CORRESPONDING TO THE CHANGES IN URINE CONCENTRATION ASSOCIATED WITH A LOW-PROTEIN DIET
CLINICAL RESEARCH Volume: 42 Page(s): A264 - A264
04/01/1994 Authors: SANDS JM; ISOZAKI T; GILLIN AG; LEA JP; SWANSON CE; TUMLIN JA -
INTRACELLULAR CALCIUM MEDIATES HYPERTONICITY STIMULATED UREA TRANSPORT IN RAT TERMINAL INNER MEDULLARY COLLECTING DUCTS
KIDNEY INTERNATIONAL Volume: 45 Page(s): 1254 - 1255
04/01/1994 Authors: GILLIN AG; STAR RA; SANDS JM -
CALCINEURIN ACTIVITY IN THE RAT NEPHRON - ROLE IN SEGMENT-SPECIFIC INHIBITION OF NA/K-ATPASE BY FK-506
CLINICAL RESEARCH Volume: 42 Page(s): A261 - A261
04/01/1994 Authors: TUMLIN JA; LEA JP; SANDS JM -
Expression of Na-K-ATPase alpha- and beta-subunit mRNA and protein isoforms in the rat nephron.
Am J Physiol Volume: 266 Page(s): F240 - F245
02/01/1994 Authors: Tumlin JA; Hoban CA; Medford RM; Sands JM -
Low protein diet alters urea transport and cell structure in rat initial inner medullary collecting duct.
J Clin Invest Volume: 92 Page(s): 2448 - 2457
11/01/1993 Authors: Isozaki T; Verlander JW; Sands JM -
The urease inhibitor acetohydroxamic acid is transported by the urea pathway in rat terminal IMCD.
Am J Physiol Volume: 265 Page(s): F385 - F390
09/01/1993 Authors: Star RA; Gillin AD; Parikh VJ; Sands JM -
THE UREASE INHIBITOR ACETOHYDROXAMIC ACID IS TRANSPORTED BY THE UREA PATHWAY IN RAT TERMINAL IMCD
AMERICAN JOURNAL OF PHYSIOLOGY Volume: 265 Page(s): F385 - F390
09/01/1993 Authors: STAR RA; GILLIN AG; PARIKH VJ; SANDS JM -
Osmolarity-stimulated urea transport in rat terminal IMCD: role of intracellular calcium.
Am J Physiol Volume: 265 Page(s): F272 - F277
08/01/1993 Authors: Gillin AG; Star RA; Sands JM -
Weekly subcutaneous erythropoietin maintains hematocrit in chronic hemodialysis patients.
J Am Soc Nephrol Volume: 3 Page(s): 1717 - 1718
04/01/1993 Authors: Parker KP; Sands JM -
SEGMENT-SPECIFIC EXPRESSION OF NA+/K+-ATPASE ALPHA-ISOFORMS AND BETA-ISOFORMS DOES NOT EXPLAIN CYCLOSPORINE-A-INDUCED NA PUMP INHIBITION
CLINICAL RESEARCH Volume: 41 Page(s): A141 - A141
04/01/1993 Authors: TUMLIN JA; SANDS JM -
A POTENTIAL MECHANISM FOR HYPERKALEMIA WITH IMMUNOSUPPRESSIVE THERAPY - COMPARISON OF CHANGES IN NA+/K+-ATPASE ACTIVITY WITH CYCLOSPORINE-A AND FK506
CLINICAL RESEARCH Volume: 41 Page(s): A326 - A326
04/01/1993 Authors: LEA JP; SANDS JM; TUMLIN JA -
Urea transport in the kidney.
Semin Nephrol Volume: 13 Page(s): 146 - 154
03/01/1993 Authors: Gillin AG; Sands JM -
UPDATE IN PHYSIOLOGY .3. INTRODUCTION
SEMINARS IN NEPHROLOGY Volume: 13 Page(s): 145 - 145
03/01/1993 Authors: KNEPPER MA; SANDS JM -
EFFECT OF HYDRATION STATUS AND LOW PROTEIN-DIET ON RENAL ALDOSE REDUCTASE AND SORBITOL DEHYDROGENASE
FASEB JOURNAL Volume: 7 Page(s): A811 - A811
02/23/1993 Authors: SANDS JM; ISOZAKI T; HOBAN CA; SWANSON CE; PRICE SR -
Nephron segment-specific inhibition of Na+/K(+)-ATPase activity by cyclosporin A.
Kidney Int Volume: 43 Page(s): 246 - 251
01/01/1993 Authors: Tumlin JA; Sands JM -
Maturation of aldose reductase expression in the neonatal rat inner medulla.
J Clin Invest Volume: 90 Page(s): 1275 - 1283
10/01/1992 Authors: Schwartz GJ; Zavilowitz BJ; Radice AD; Garcia-Perez A; Sands JM -
CHARACTERISTICS OF OSMOLARITY-STIMULATED UREA TRANSPORT IN RAT IMCD
AMERICAN JOURNAL OF PHYSIOLOGY Volume: 262 Page(s): F1061 - F1067
06/01/1992 Authors: GILLIN AG; SANDS JM -
Urinary concentrating ability in patients with Jk(a-b-) blood type who lack carrier-mediated urea transport.
J Am Soc Nephrol Volume: 2 Page(s): 1689 - 1696
06/01/1992 Authors: Sands JM; Gargus JJ; Frhlich O; Gunn RB; Kokko JP -
Characteristics of osmolarity-stimulated urea transport in rat IMCD.
Am J Physiol Volume: 262 Page(s): F1061 - F1067
06/01/1992 Authors: Gillin AG; Sands JM -
POTENTIAL MECHANISM FOR CYCLOSPORINE-INDUCED HYPERKALEMIA - CYCLOSPORINE-A INHIBITS NA/K ATPASE ACTIVITY IN NEPHRON SEGMENTS IMPORTANT TO POTASSIUM SECRETION
CLINICAL RESEARCH Volume: 40 Page(s): A178 - A178
04/01/1992 Authors: TUMLIN JA; SANDS JM -
DEMONSTRATION OF ACTIVE UREA TRANSPORT IN RAT INITIAL INNER MEDULLARY COLLECTING DUCT (IMCD) - RESPONSE TO DIETARY-PROTEIN RESTRICTION
FASEB JOURNAL Volume: 6 Page(s): A957 - A957
02/26/1992 Authors: ISOZAKI T; SANDS JM -
Acute changes in intracellular ions or pH and regulation of aldose reductase activity.
J Am Soc Nephrol Volume: 2 Page(s): 212 - 218
08/01/1991 Authors: Sands JM; Schrader DC -
An independent effect of osmolality on urea transport in rat terminal inner medullary collecting ducts.
J Clin Invest Volume: 88 Page(s): 137 - 142
07/01/1991 Authors: Sands JM; Schrader DC -
AN INDEPENDENT EFFECT OF OSMOLALITY ON UREA PERMEABILITY IN RAT TERMINAL INNER MEDULLARY COLLECTING DUCT
FASEB JOURNAL Volume: 5 Page(s): A1110 - A1110
03/15/1991 Authors: SCHRADER DC; SANDS JM -
Atrial natriuretic factor does not improve the outcome of cadaveric renal transplantation.
J Am Soc Nephrol Volume: 1 Page(s): 1081 - 1086
03/01/1991 Authors: Sands JM; Neylan JF; Olson RA; O'Brien DP; Whelchel JD; Mitch WE -
Coordinated response of aldose reductase and sorbitol dehydrogenase regulates net sorbitol production in the rat renal inner medulla.
Contrib Nephrol Volume: 95 Page(s): 272 - 278
01/01/1991 Authors: Sands JM; Schrader DC -
Countercurrent system.
Kidney Int Volume: 38 Page(s): 695 - 699
10/01/1990 Authors: Sands JM; Kokko JP -
Coordinated response of renal medullary enzymes regulating net sorbitol production in diuresis and antidiuresis.
J Am Soc Nephrol Volume: 1 Page(s): 58 - 65
07/01/1990 Authors: Sands JM; Schrader DC -
Hemolytic-uremic syndrome following "crack" cocaine inhalation.
Am J Med Sci Volume: 299 Page(s): 366 - 371
06/01/1990 Authors: Tumlin JA; Sands JM; Someren A -
UREA GRADIENT-ASSOCIATED FLUID ABSORPTION WITH SIGMA-UREA = 1 IN RAT TERMINAL COLLECTING DUCT
AMERICAN JOURNAL OF PHYSIOLOGY Volume: 258 Page(s): F1173 - F1180
05/01/1990 Authors: CHOU CL; SANDS JM; NONOGUCHI H; KNEPPER MA -
Urea gradient-associated fluid absorption with sigma urea = 1 in rat terminal collecting duct.
Am J Physiol Volume: 258 Page(s): F1173 - F1180
05/01/1990 Authors: Chou CL; Sands JM; Nonoguchi H; Knepper MA -
ALDOSE REDUCTASE AND SORBITOL DEHYDROGENASE ARE INVOLVED IN CHRONIC, BUT NOT ACUTE, OSMOREGULATION IN THE INNER MEDULLA
CLINICAL RESEARCH Volume: 38 Page(s): A358 - A358
04/01/1990 Authors: SANDS JM; SCHRADER DC -
Concentration dependence of urea and thiourea transport in rat inner medullary collecting duct.
Am J Physiol Volume: 258 Page(s): F486 - F494
03/01/1990 Authors: Chou CL; Sands JM; Nonoguchi H; Knepper MA -
REGULATION OF INTRACELLULAR SORBITOL IN MICRODISSECTED RAT INNER MEDULLARY COLLECTING DUCT SEGMENTS BY STATE OF HYDRATION
CLINICAL RESEARCH Volume: 38 Page(s): A22 - A22
01/01/1990 Authors: SANDS JM; SCHRADER DC -
MECHANISM OF UREA-LINKED WATER FLUX IN RAT INNER MEDULLARY COLLECTING DUCT (IMCD)
KIDNEY INTERNATIONAL Volume: 37 Page(s): 578 - 578
01/01/1990 Authors: CHOU CL; SANDS JM; KNEPPER MA -
ALDOSE REDUCTASE AND SORBITOL DEHYDROGENASE-ACTIVITIES VARY WITH HYDRATION IN MICRODISSECTED RAT INNER MEDULLARY COLLECTING DUCT SEGMENTS
KIDNEY INTERNATIONAL Volume: 37 Page(s): 588 - 588
01/01/1990 Authors: SANDS JM; SCHRADER DC -
Net acid transport by isolated perfused inner medullary collecting ducts.
Am J Physiol Volume: 258 Page(s): F75 - F84
01/01/1990 Authors: Wall SM; Sands JM; Flessner MF; Nonoguchi H; Spring KR; Knepper MA -
Renal actions of atrial natriuretic factor: a mathematical modeling study.
Am J Physiol Volume: 257 Page(s): F1146 - F1157
12/01/1989 Authors: Mejia R; Sands JM; Stephenson JL; Knepper MA -
Chloride and osmotic water permeabilities of isolated rabbit renal papillary surface epithelium.
Am J Physiol Volume: 257 Page(s): F218 - F224
08/01/1989 Authors: Packer RK; Sands JM; Knepper MA -
MODULATION OF VASOPRESSIN-DEPENDENT UREA TRANSPORT IN RAT INNER MEDULLARY COLLECTING DUCT BY PERITUBULAR NACL AND UREA
CLINICAL RESEARCH Volume: 37 Page(s): A580 - A580
04/01/1989 Authors: CHOU CL; NONOGUCHI H; SANDS JM; KNEPPER MA -
Independence of urea and water transport in rat inner medullary collecting duct.
Am J Physiol Volume: 256 Page(s): F610 - F621
04/01/1989 Authors: Knepper MA; Sands JM; Chou CL -
Aldose reductase activities in microdissected rat renal tubule segments.
Am J Physiol Volume: 256 Page(s): F563 - F569
04/01/1989 Authors: Sands JM; Terada Y; Bernard LM; Knepper MA -
ANF inhibits NaCl and fluid absorption in cortical collecting duct of rat kidney.
Am J Physiol Volume: 256 Page(s): F179 - F186
01/01/1989 Authors: Nonoguchi H; Sands JM; Knepper MA -
ALDOSE REDUCTASE ACTIVITIES IN MICRODISSECTED RAT NEPHRON SEGMENTS
KIDNEY INTERNATIONAL Volume: 35 Page(s): 501 - 501
01/01/1989 Authors: SANDS JM; TERADA Y; BERNARD LM; BURG MB; KNEPPER MA -
NET ACID-SECRETION IN ISOLATED PERFUSED RAT INNER MEDULLARY COLLECTING DUCTS
KIDNEY INTERNATIONAL Volume: 35 Page(s): 465 - 465
01/01/1989 Authors: WALL SM; SANDS JM; KNEPPER MA -
Atrial natriuretic factor inhibits vasopressin-stimulated osmotic water permeability in rat inner medullary collecting duct.
J Clin Invest Volume: 82 Page(s): 1383 - 1390
10/01/1988 Authors: Nonoguchi H; Sands JM; Knepper MA -
Hormone effects on NaCl permeability of rat inner medullary collecting duct.
Am J Physiol Volume: 255 Page(s): F421 - F428
09/01/1988 Authors: Sands JM; Nonoguchi H; Knepper MA -
ATRIAL NATRIURETIC FACTOR INHIBITS REABSORPTION OF SODIUM AND FLUID IN ISOLATED PERFUSED CORTICAL COLLECTING DUCTS FROM RATS
CLINICAL RESEARCH Volume: 36 Page(s): A524 - A524
04/01/1988 Authors: NONOGUCHI H; SANDS JM; KNEPPER MA -
LACK OF SOLVENT DRAG OF UREA IN THE RAT INNER MEDULLARY COLLECTING DUCT
CLINICAL RESEARCH Volume: 36 Page(s): A526 - A526
04/01/1988 Authors: SANDS JM; NONOGUCHI H; KNEPPER MA -
SODIUM-CHLORIDE AND OSMOTIC WATER PERMEABILITIES OF ISOLATED RABBIT PAPILLARY SURFACE EPITHELIUM - EFFECTS OF VASOPRESSIN
KIDNEY INTERNATIONAL Volume: 33 Page(s): 280 - 280
01/01/1988 Authors: PACKER RK; SANDS JM; KNEPPER MA -
ATRIAL NATRIURETIC FACTOR INHIBITS VASOPRESSIN-STIMULATED OSMOTIC WATER PERMEABILITY IN RAT INNER MEDULLARY COLLECTING DUCT
KIDNEY INTERNATIONAL Volume: 33 Page(s): 278 - 278
01/01/1988 Authors: NONOGUCHI H; SANDS JM; KNEPPER MA -
Vasopressin effects on urea and H2O transport in inner medullary collecting duct subsegments.
Am J Physiol Volume: 253 Page(s): F823 - F832
11/01/1987 Authors: Sands JM; Nonoguchi H; Knepper MA -
AXIAL HETEROGENEITY OF RAT INNER MEDULLARY COLLECTING DUCT - VASOPRESSIN EFFECTS ON UREA AND WATER TRANSPORT
FEDERATION PROCEEDINGS Volume: 46 Page(s): 1285 - 1285
03/05/1987 Authors: SANDS JM; NONOGUCHI H; KNEPPER MA -
Urea permeability of mammalian inner medullary collecting duct system and papillary surface epithelium.
J Clin Invest Volume: 79 Page(s): 138 - 147
01/01/1987 Authors: Sands JM; Knepper MA -
EFFECTS OF VASOPRESSIN AND ATRIAL-NATRIURETIC-FACTOR ON OSMOTIC WATER PERMEABILITY AND UREA PERMEABILITY OF RAT INNER MEDULLARY COLLECTING DUCT SEGMENTS
KIDNEY INTERNATIONAL Volume: 31 Page(s): 450 - 450
01/01/1987 Authors: SANDS JM; NONOGUCHI H; KNEPPER MA -
Na-K-Cl cotransport in apical membrane of rabbit renal papillary surface epithelium.
Am J Physiol Volume: 251 Page(s): F475 - F484
09/01/1986 Authors: Sands JM; Knepper MA; Spring KR -
CELL-VOLUME RESPONSE TO APICAL OSMOLALITY CHANGES IN ISOLATED RABBIT RENAL PAPILLARY SURFACE EPITHELIUM
CLINICAL RESEARCH Volume: 34 Page(s): A607 - A607
04/01/1986 Authors: SANDS JM; SPRING KR; KNEPPER MA -
NA-K-CL COTRANSPORT IN APICAL MEMBRANE OF RABBIT RENAL PAPILLARY SURFACE EPITHELIUM
KIDNEY INTERNATIONAL Volume: 29 Page(s): 406 - 406
01/01/1986 Authors: SANDS JM; KNEPPER MA; SPRING KR -
UREA PERMEABILITY OF INNER MEDULLARY COLLECTING DUCT AND PAPILLARY SURFACE EPITHELIUM
KIDNEY INTERNATIONAL Volume: 29 Page(s): 418 - 418
01/01/1986 Authors: KNEPPER MA; SANDS JM -
Transmembrane potential of renal papillary epithelial cells: effect of urea and DDAVP.
Am J Physiol Volume: 248 Page(s): F762 - F766
06/01/1985 Authors: Sands JM; Ivy EJ; Beeuwkes R -
Disseminated infection caused by Cunninghamella bertholletiae in a patient with beta-thalassemia. Case report and review of the literature.
Ann Intern Med Volume: 102 Page(s): 59 - 63
01/01/1985 Authors: Sands JM; Macher AM; Ley TJ; Nienhuis AW -
RENAL PAPILLARY EPITHELIAL-CELLS - EFFECT OF DDAVP, PHLORETIN, AND AMILORIDE ON UREA-DEPENDENT TRANS-MEMBRANE POTENTIAL DIFFERENCE (PD)
KIDNEY INTERNATIONAL Volume: 16 Page(s): 840 - 840
01/01/1979 Authors: TERESI LM; SANDS JM; BEEUWKES R -
UREA EFFECT ON PAPILLARY EPITHELIAL TRANSMEMBRANE POTENTIAL DIFFERENCE (PD) IS TRIPHASIC
KIDNEY INTERNATIONAL Volume: 14 Page(s): 783 - 783
01/01/1978 Authors: TERESI LM; SANDS JM; BEEUWKES R -
UREA CHANGES TRANSMEMBRANE POTENTIAL DIFFERENCE OF PAPILLARY EPITHELIAL-CELLS
KIDNEY INTERNATIONAL Volume: 12 Page(s): 572 - 572
01/01/1977 Authors: SANDS JM; BEEUWKES R