James Ritchie PhD
Academic Appointment
- Professor, Department of Pathology & Laboratory Medicine, Emory University School of Medicine
- Professor, Department of Psychiatry and Behavioral Medicine, Emory University School of Medicine
- Assistant Professor, Department of Psychiatry and Behavioral Medicine, Emory University School of Medicine
Education
Degrees
- Doctor of Philosophy from Duke University
- Bachelor of Science from The University of Michigan
- Master of Public Health from The University of Michigan
Research
Focus
- My research is currently focused on the pharmacokinetics/pharmacodynamics of antidepressants and anti-seizure medications during pregnancy. We are actively developing multiplexed LC/MS/MS assays to measure these drugs in small samples. I am also persuing investigations into the use of plasma and urine proteomics as a new tool for the clinical laboratory.
Publications
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Phase 1 Open-Label Dose Escalation Trial for the Development of a Human Bacillus Calmette-Gurin Challenge Model for Assessment of Tuberculosis Immunity In Vivo.
J Infect Dis Volume: 229 Page(s): 1498 - 1508
05/15/2024 Authors: Blazevic A; Edwards RL; Xia M; Eickhoff CS; Hamzabegovic F; Meza KA; Ning H; Tennant J; Mosby KJ; Ritchie JC -
Differential Potency of Venlafaxine, Paroxetine, and Atomoxetine to Inhibit Serotonin and Norepinephrine Reuptake in Patients With Major Depressive Disorder.
Int J Neuropsychopharmacol Volume: 25 Page(s): 283 - 292
04/19/2022 Authors: Aldosary F; Norris S; Tremblay P; James JS; Ritchie JC; Blier P -
Quality Control of Busulfan Plasma Quantitation, Modeling, and Dosing: An Interlaboratory Proficiency Testing Program.
Ther Drug Monit Volume: 43 Page(s): 657 - 663
10/01/2021 Authors: McCune JS; Punt AM; Yeh RF; Dupuis LL; Kweekel DM; Franssen EJF; Ritchie JC; van Maarseveen E; Huitema ADR -
Response to Kawedia et al Letter to Editor in Response to the Article by McCune Et Al "Harmonization of Busulfan Plasma Exposure Unit (BPEU): A Community-Initiated Consensus Statement".
Biol Blood Marrow Transplant Volume: 26 Page(s): e235 - e236
09/01/2020 Authors: Dupuis LL; Quinones CM; Ritchie J; Carpenter PA; Bauters T; Yeh RF; Anasetti C; Boelens JJ; Hamerschlak N; Hassan M -
Serosurvey on healthcare personnel caring for patients with Ebola virus disease and Lassa virus in the United States.
Infect Control Hosp Epidemiol Volume: 41 Page(s): 385 - 390
04/01/2020 Authors: Kraft CS; Mehta AK; Varkey JB; Lyon GM; Vanairsdale S; Bell S; Burd EM; Sexton ME; Cassidy LA; Olinger P -
Does Lidocaine Cause False Positive Results on Cocaine Urine Drug Screen?
J Med Toxicol Volume: 15 Page(s): 255 - 261
10/01/2019 Authors: Kim E; Murray BP; Salehi M; Moran TP; Carpenter JE; Koch DD; Ritchie JC; Schindler JM; Morgan BW -
Harmonization of Busulfan Plasma Exposure Unit (BPEU): A Community-Initiated Consensus Statement.
Biol Blood Marrow Transplant Volume: 25 Page(s): 1890 - 1897
09/01/2019 Authors: McCune JS; Quinones CM; Ritchie J; Carpenter PA; van Maarseveen E; Yeh RF; Anasetti C; Boelens JJ; Hamerschlak N; Hassan M -
Fetal Antidepressant Exposure and Outcomes
Volume: 85 Page(s): S319 - S319
05/15/2019 Authors: Kalin M; Cochran A; Newport DJ; Knight B; Morris N; Ritchie J; Owens M; Stowe Z -
Fast Feedback Inhibition of Adrenocorticotropic Hormone Secretion by Endogenous Cortisol in Humans.
Neuroendocrinology Volume: 109 Page(s): 299 - 309
01/01/2019 Authors: Carroll BJ; Ritchie JC; Rogers H; Kim DK -
Antiepileptic drug clearances during pregnancy and clinical implications for women with epilepsy.
Neurology Volume: 91 Page(s): e1228 - e1236
09/25/2018 Authors: Voinescu PE; Park S; Chen LQ; Stowe ZN; Newport DJ; Ritchie JC; Pennell PB -
Course of ante- and postnatal depressive symptoms related to mothers' HPA axis regulation.
J Abnorm Psychol Volume: 127 Page(s): 404 - 416
05/01/2018 Authors: Laurent H; Goodman SH; Stowe ZN; Halperin M; Khan F; Wright D; Nelson BW; Newport DJ; Ritchie JC; Monk C -
The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice.
Sci Rep Volume: 8 Page(s): 3840
03/01/2018 Authors: Manvich DF; Webster KA; Foster SL; Farrell MS; Ritchie JC; Porter JH; Weinshenker D -
Laboratory Medicine in Pain Management: Evolution to Guidelines - Defining a Standard of Care.
J Appl Lab Med Volume: 2 Page(s): 473 - 474
01/01/2018 Authors: Ritchie J -
Preliminary Study of Testosterone and Empathy in Determining Recidivism and Antisocial Behavior.
J Forensic Sci Volume: 62 Page(s): 1360 - 1365
09/01/2017 Authors: House SJ; Laan JM; Molden RK; Ritchie JC; Stowe ZN -
Response to Letter: "Calcium and Bone Turnover Markers in Acromegaly: A Prospective, Controlled Study".
J Clin Endocrinol Metab Volume: 102 Page(s): 3561 - 3562
09/01/2017 Authors: Constantin T; Tangpricha V; Shah R; Oyesiku NM; Ioachimescu O; Ritchie J; Ioachimescu AG -
Calcium and Bone Turnover Markers in Acromegaly: A Prospective, Controlled Study.
J Clin Endocrinol Metab Volume: 102 Page(s): 2416 - 2424
07/01/2017 Authors: Constantin T; Tangpricha V; Shah R; Oyesiku NM; Ioachimescu OC; Ritchie J; Ioachimescu AG -
Effects of Patient Preferences on Outcomes in the Predictors of Remission in Depression to Individual and Combined Treatments (PReDICT) Study.
Am J Psychiatry Volume: 174 Page(s): 546 - 556
06/01/2017 Authors: Dunlop BW; Kelley ME; Aponte-Rivera V; Mletzko-Crowe T; Kinkead B; Ritchie JC; Nemeroff CB; Craighead WE; Mayberg HS; PReDICT Team -
Placental passage of antiepileptic drugs at delivery and neonatal outcomes.
Epilepsia Volume: 58 Page(s): e82 - e86
05/01/2017 Authors: Bank AM; Stowe ZN; Newport DJ; Ritchie JC; Pennell PB -
A Targeted, Evidence-Based Clinical Decision Support Intervention to Reduce Unnecessary Complete Blood Count Orders
Volume: 147 Page(s): S154 - +
03/01/2017 Authors: Feldhammer M; Menasco D; Zhang W; Ritchie J -
Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for Nicotine and Its Metabolites Reveals a Low Clinical Utility for the Tobacco Alkaloid Anabasine
Volume: 147
03/01/2017 Authors: Feldhammer M; Menasco D; Zhang W; Ritchie J -
A Targeted, Evidence-Based Clinical Decision Support Intervention to Reduce Unnecessary Complete Blood Count Orders.
Am J Clin Pathol Volume: 147 Page(s): S158
03/01/2017 Authors: Feldhammer M; Menasco D; Zhang W; Ritchie J -
Anabasine Is a Poor Marker for Determining Smoking Status of Transplant Patients.
Clin Chem Volume: 63 Page(s): 604 - 606
02/01/2017 Authors: Feldhammer M; Ritchie JC -
Exposure to Paliperidone in Utero and via Breast Milk: Drug Clearance and Implications for an Animal Model of Human Exposure
Volume: 41 Page(s): S172 - S172
12/01/2016 Authors: Owens M; Zejnelovic F; Ritchie J; Zhang F; Jin P; Plott S -
Time-dependent effects of dexamethasone plasma concentrations on glucocorticoid receptor challenge tests.
Psychoneuroendocrinology Volume: 69 Page(s): 161 - 171
07/01/2016 Authors: Menke A; Arloth J; Best J; Namendorf C; Gerlach T; Czamara D; Lucae S; Dunlop BW; Crowe TM; Garlow SJ -
DNA variants in CACNA1C modify Parkinson disease risk only when vitamin D level is deficient.
Neurol Genet Volume: 2 Page(s): e72
06/01/2016 Authors: Wang L; Maldonado L; Beecham GW; Martin ER; Evatt ML; Ritchie JC; Haines JL; Zabetian CP; Payami H; Pericak-Vance MA -
Comprehensive evaluation of thyrotropinomas: single-center 20-year experience.
Pituitary Volume: 19 Page(s): 183 - 193
04/01/2016 Authors: Azzalin A; Appin CL; Schniederjan MJ; Constantin T; Ritchie JC; Veledar E; Oyesiku NM; Ioachimescu AG -
Reprint of: Locus coeruleus neuronal activity determines proclivity to consume alcohol in a selectively-bred line of rats that readily consumes alcohol.
Alcohol Volume: 50 Page(s): 91 - 105
02/01/2016 Authors: West CHK; Boss-Williams KA; Ritchie JC; Weiss JM -
Quantitation of the Oral Anticoagulants Dabigatran, Rivaroxaban, Apixaban, and Warfarin in Plasma Using Ultra-Performance Liquid Chromatography with Tandem Mass Spectrometry (UPLC-MS/MS).
Methods Mol Biol Volume: 1383 Page(s): 21 - 27
01/01/2016 Authors: Noguez JH; Ritchie JC -
Locus coeruleus neuronal activity determines proclivity to consume alcohol in a selectively-bred line of rats that readily consumes alcohol.
Alcohol Volume: 49 Page(s): 691 - 705
11/01/2015 Authors: West CHK; Boss-Williams KA; Ritchie JC; Weiss JM -
Comparison of FilmArray and Quantitative Real-Time Reverse Transcriptase PCR for Detection of Zaire Ebolavirus from Contrived and Clinical Specimens.
J Clin Microbiol Volume: 53 Page(s): 2956 - 2960
09/01/2015 Authors: Southern TR; Racsa LD; Albario CG; Fey PD; Hinrichs SH; Murphy CN; Herrera VL; Sambol AR; Hill CE; Ryan EL -
The Use of TKM-100802 and Convalescent Plasma in 2 Patients With Ebola Virus Disease in the United States.
Clin Infect Dis Volume: 61 Page(s): 496 - 502
08/15/2015 Authors: Kraft CS; Hewlett AL; Koepsell S; Winkler AM; Kratochvil CJ; Larson L; Varkey JB; Mehta AK; Lyon GM; Friedman-Moraco RJ -
Vitamin D from different sources is inversely associated with Parkinson disease.
Mov Disord Volume: 30 Page(s): 560 - 566
04/01/2015 Authors: Wang L; Evatt ML; Maldonado LG; Perry WR; Ritchie JC; Beecham GW; Martin ER; Haines JL; Pericak-Vance MA; Vance JM -
Absolute and relative changes (delta) in troponin I for early diagnosis of myocardial infarction: Results of a prospective multicenter trial.
Clin Biochem Volume: 48 Page(s): 260 - 267
03/01/2015 Authors: Storrow AB; Nowak RM; Diercks DB; Singer AJ; Wu AHB; Kulstad E; LoVecchio F; Fromm C; Headden G; Potis T -
Diagnostic performance of cardiac Troponin I for early rule-in and rule-out of acute myocardial infarction: Results of a prospective multicenter trial.
Clin Biochem Volume: 48 Page(s): 254 - 259
03/01/2015 Authors: Storrow AB; Christenson RH; Nowak RM; Diercks DB; Singer AJ; Wu AHB; Kulstad E; LoVecchio F; Fromm C; Headden G -
A Novel Method for Monitoring Therapy and Guiding Treatment Decisions in a New Era of Anticoagulants
Volume: 142 Page(s): 711 - 711
11/01/2014 Authors: Noguez J; Ritchie J -
Early predictive biomarkers for postpartum depression point to a role for estrogen receptor signaling.
Psychol Med Volume: 44 Page(s): 2309 - 2322
08/01/2014 Authors: Mehta D; Newport DJ; Frishman G; Kraus L; Rex-Haffner M; Ritchie JC; Lori A; Knight BT; Stagnaro E; Ruepp A -
Pleiotropic Manifestations of TSH-Secreting Pituitary Adenomas: Emory University Case Series
ENDOCRINE REVIEWS Volume: 35
06/01/2014 Authors: Azzalin A; Appin C; Puttnam RP; Ritchie J; Brat D; Oyesiku NM; Ioachimescu AG -
Albumin adsorption onto surfaces of urine collection and analysis containers.
Clin Chim Acta Volume: 431 Page(s): 40 - 45
04/20/2014 Authors: Robinson MK; Caudill SP; Koch DD; Ritchie J; Hortin G; Eckfeldt JH; Sandberg S; Williams D; Myers G; Miller WG -
Carbamazepine clearance and seizure stability during pregnancy.
Epilepsy Behav Volume: 33 Page(s): 49 - 53
04/01/2014 Authors: Johnson EL; Stowe ZN; Ritchie JC; Newport DJ; Newman ML; Knight B; Pennell PB -
Development and validation of a liquid chromatography-tandem mass spectrometry assay to quantify plasma busulfan.
Ther Drug Monit Volume: 36 Page(s): 169 - 174
04/01/2014 Authors: French D; Sujishi KK; Long-Boyle JR; Ritchie JC -
Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach.
Mol Cell Proteomics Volume: 13 Page(s): 907 - 917
03/01/2014 Authors: Carr SA; Abbatiello SE; Ackermann BL; Borchers C; Domon B; Deutsch EW; Grant RP; Hoofnagle AN; Httenhain R; Koomen JM -
MODEL-BASED LAMOTRIGINE CLEARANCE CHANGES DURING PREGNANCY: CLINICAL IMPLICATION.
Ann Clin Transl Neurol Volume: 1 Page(s): 99 - 106
02/01/2014 Authors: Polepally AR; Pennell PB; Brundage RC; Stowe ZN; Newport DJ; Viguera AC; Ritchie JC; Birnbaum AK -
Laboratory test support for Ebola patients within a high-containment facility.
Lab Med Volume: 45 Page(s): e109 - e111
01/01/2014 Authors: Hill CE; Burd EM; Kraft CS; Ryan EL; Duncan A; Winkler AM; Cardella JC; Ritchie JC; Parslow TG -
Unintended reporting of misleading Hb A(1c) values when using assays incapable of detecting hemoglobin variants.
Arch Pathol Lab Med Volume: 137 Page(s): 1788 - 1791
12/01/2013 Authors: Rhea JM; Koch D; Ritchie J; Singh HV; Young AN; Burgess T; Molinaro RJ -
Therapeutic Drug Monitoring of Antiepileptic Drugs During Pregnancy
Volume: 35 Page(s): 694 - 694
10/01/2013 Authors: Ritchie JC; Scott-Harrell P; Ramsey CH; Lukacin R -
Evaluation of Deuterium-Labeled Internal Standards for the Multiplex Measurement of Cyclosporin A, Sirolimus, and Tacrolimus by HPLC Electrospray Ionization Tandem Mass Spectrometry (LC-MS/MS)
Volume: 140 Page(s): 432 - 432
09/01/2013 Authors: Bryksin JA; Ritchie JC -
Falsely increased HCG in patients with high leukocyte counts.
Clin Chem Volume: 59 Page(s): 1127 - 1129
07/01/2013 Authors: Snyder ML; Wiley C; Molinaro RJ; Ritchie JC; Fantz CR -
Rate Sensitive Immediate Feedback Inhibition of ACTH Secretionby Endogenous Cortisol in Human CRH Test
Volume: 73 Page(s): 204S - 205S
05/01/2013 Authors: Carroll BJ; Kim DK; Rogers H; Ritchie JC -
Development of a liquid chromatography tandem mass spectrometry method for iothalamate measurement to assess renal function for potential kidney donation.
Clin Chim Acta Volume: 420 Page(s): 104 - 108
05/01/2013 Authors: Rhea JM; Ritchie JC; Molinaro RJ -
Adrenocortical Sensitivity to Endogenous ACTH in the CRH Test
Volume: 73 Page(s): 314S - 314S
05/01/2013 Authors: Carroll BJ; Kim DK; Rogers H; Ritchie JC -
Carbamazepine Clearance and Seizure Control during Pregnancy
Volume: 80
02/12/2013 Authors: Johnson E; Stowe Z; Ritchie J; Newport DJ; Newman M; Secor E; Knight B; Pennell P -
Modulation of vigilance in the primary hypersomnias by endogenous enhancement of GABAA receptors.
Sci Transl Med Volume: 4 Page(s): 161ra151
11/21/2012 Authors: Rye DB; Bliwise DL; Parker K; Trotti LM; Saini P; Fairley J; Freeman A; Garcia PS; Owens MJ; Ritchie JC -
Evaluation of Two Years of a Medical Student Clinical Laboratory Experience
Volume: 138 Page(s): A376 - A376
11/01/2012 Authors: Molinaro RJ; Winkler A; Bunting S; Koch D; Ritchie J; Edgar M; Kinsella M; Rogers B; Fantz C; Guarner J -
Teaching laboratory medicine to medical students: implementation and evaluation.
Arch Pathol Lab Med Volume: 136 Page(s): 1423 - 1429
11/01/2012 Authors: Molinaro RJ; Winkler AM; Kraft CS; Fantz CR; Stowell SR; Ritchie JC; Koch DD; Heron S; Liebzeit J; Santen SA -
Predictors of remission in depression to individual and combined treatments (PReDICT): study protocol for a randomized controlled trial.
Trials Volume: 13 Page(s): 106
07/09/2012 Authors: Dunlop BW; Binder EB; Cubells JF; Goodman MM; Kelley ME; Kinkead B; Kutner M; Nemeroff CB; Newport DJ; Owens MJ -
Levels of cerebrospinal fluid neurofilament light protein in healthy elderly vary as a function of TOMM40 variants.
Exp Gerontol Volume: 47 Page(s): 347 - 352
05/01/2012 Authors: Bruno D; Pomara N; Nierenberg J; Ritchie JC; Lutz MW; Zetterberg H; Blennow K -
Development of a fast and simple liquid chromatography-tandem mass spectrometry method for the quantitation of argatroban in patient plasma samples.
J Chromatogr B Analyt Technol Biomed Life Sci Volume: 893-894 Page(s): 168 - 172
04/15/2012 Authors: Rhea JM; Snyder ML; Winkler AM; Abou-Diwan C; Fantz CR; Ritchie JC; Szlam F; Tanaka KA; Molinaro RJ -
Improved sensitivity for methotrexate analysis using enzyme multiplied immunoassay technique on the Siemens Viva-E instrument.
Ther Drug Monit Volume: 34 Page(s): 193 - 197
04/01/2012 Authors: Borgman MP; Hiemer MF; Molinelli AR; Ritchie JC; Jortani SA -
Influence of chronic administration of antidepressant drugs on mRNA for galanin, galanin receptors, and tyrosine hydroxylase in catecholaminergic and serotonergic cell-body regions in rat brain.
Neuropeptides Volume: 46 Page(s): 81 - 91
04/01/2012 Authors: Rovin ML; Boss-Williams KA; Alisch RS; Ritchie JC; Weinshenker D; West CHK; Weiss JM -
Relationship between dose, drug levels, and D2 receptor occupancy for the atypical antipsychotics risperidone and paliperidone.
J Pharmacol Exp Ther Volume: 341 Page(s): 81 - 89
04/01/2012 Authors: Muly EC; Votaw JR; Ritchie J; Howell LL -
Cerebrospinal fluid cortisol concentrations in healthy elderly are affected by both APOE and TOMM40 variants.
Psychoneuroendocrinology Volume: 37 Page(s): 366 - 371
03/01/2012 Authors: Bruno D; Nierenberg JJ; Ritchie JC; Lutz MW; Pomara N -
Pathogenesis of marked pituitary enlargement and increased serum thyroid-stimulating hormone in primary hypothyroidism.
Thyroid Volume: 22 Page(s): 101 - 102
01/01/2012 Authors: Eiland L; Oyesiku NM; Ritchie JC; Isaacs S; Ioachimescu AG -
Immune activation mediated change in alpha-1-acid glycoprotein: impact on total and free lopinavir plasma exposure.
J Clin Pharmacol Volume: 51 Page(s): 1539 - 1548
11/01/2011 Authors: Ofotokun I; Lennox JL; Eaton ME; Ritchie JC; Easley KA; Masalovich SE; Long MC; Acosta EP -
Serotonin transporter occupancy in rats exposed to serotonin reuptake inhibitors in utero or via breast milk.
J Pharmacol Exp Ther Volume: 339 Page(s): 275 - 285
10/01/2011 Authors: Capello CF; Bourke CH; Ritchie JC; Stowe ZN; Newport DJ; Nemeroff A; Owens MJ -
Endogenous GABA(A) Receptor Enhancement Modulates Vigilance in the Primary Hypersomnias
Volume: 70 Page(s): S23 - S23
10/01/2011 Authors: Rye DB; Parker K; Trotti LM; Garcia PS; Ritchie JC; Owens MJ; Morrow L; Bliwise DL; Jenkins A -
Determination of Cocaine Metabolites and the Adulterant Levamisole in Urine Using UPLC-MS/MS
Volume: 136 Page(s): 463 - 463
09/01/2011 Authors: Abou-Diwan C; Koch DD; Ritchie JC -
Proteomics of gliomas: initial biomarker discovery and evolution of technology.
Neuro Oncol Volume: 13 Page(s): 926 - 942
09/01/2011 Authors: Kalinina J; Peng J; Ritchie JC; Van Meir EG -
Predictors of neonatal hypothalamic-pituitary-adrenal axis activity at delivery.
Clin Endocrinol (Oxf) Volume: 75 Page(s): 90 - 95
07/01/2011 Authors: Smith AK; Newport DJ; Ashe MP; Brennan PA; Laprairie JL; Calamaras M; Nemeroff CB; Ritchie JC; Cubells JF; Stowe ZN -
The journey to regulation of protein-based multiplex quantitative assays.
Clin Chem Volume: 57 Page(s): 560 - 567
04/01/2011 Authors: Boja ES; Jortani SA; Ritchie J; Hoofnagle AN; Teak ; Mansfield E; Keller P; Rivers RC; Rahbar A; Anderson NL -
Plasma and cerebral spinal fluid tranexamic acid quantitation in cardiopulmonary bypass patients.
J Chromatogr B Analyt Technol Biomed Life Sci Volume: 879 Page(s): 553 - 556
03/01/2011 Authors: Abou-Diwan C; Sniecinski RM; Szlam F; Ritchie JC; Rhea JM; Tanaka KA; Molinaro RJ -
SEVERELY ELEVATED TSH LEVEL AND PITUITARY ENLARGEMENT IN A PATIENT WITH PRIMARY AUTOIMMUNE HYPOTHYROIDISM: CASE REPORT AND REVIEW OF LITERATURE
Volume: 59 Page(s): 411 - 411
02/01/2011 Authors: Eiland L; Oyesiku NM; Ritchie JC; Isaacs S; Ioachimescu AG -
Pulmonary embolism in a patient with catatonia: an old disease, changing times.
Psychosomatics Volume: 52 Page(s): 387 - 391
01/01/2011 Authors: Larsen HH; Ritchie JC; McNutt MD; Musselman DL -
A fast and simple assay for busulfan in serum or plasma by liquid chromatography-tandem mass spectrometry using turbulent flow online extraction technology.
J Chromatogr B Analyt Technol Biomed Life Sci Volume: 878 Page(s): 3255 - 3258
12/01/2010 Authors: Bunch DR; Heideloff C; Ritchie JC; Wang S -
Total 25-Hydroxyvitamin D Method Comparison Between Two Commercially Available Automated Immunoassays
Volume: 134 Page(s): 504 - 505
09/01/2010 Authors: Chin AC; Ramsey CH; Roberts WL; Ritchie JC -
Addendum: Paroxetine-induced increase in activity of locus coeruleus neurons in adolescent rats: implication of a countertherapeutic effect of an antidepressant.
Neuropsychopharmacology Volume: 35 Page(s): 1836 - 1837
07/01/2010 Authors: West CHK; Ritchie JC; Weiss JM -
Paroxetine-induced increase in activity of locus coeruleus neurons in adolescent rats: implication of a countertherapeutic effect of an antidepressant.
Neuropsychopharmacology Volume: 35 Page(s): 1653 - 1663
07/01/2010 Authors: West CHK; Ritchie JC; Weiss JM -
Quantification of busulfan in plasma using liquid chromatography electrospray tandem mass spectrometry (HPLC-ESI-MS/MS).
Methods Mol Biol Volume: 603 Page(s): 129 - 136
01/01/2010 Authors: Snyder ML; Ritchie JC -
Monitoring of mycophenolate acid in serum or plasma using LC tandem mass spectrometry.
Methods Mol Biol Volume: 603 Page(s): 379 - 387
01/01/2010 Authors: Hammett-Stabler CA; Geis DC; Ritchie JC; Papadea C -
Quantitation of iothalamate in urine and plasma using liquid chromatography electrospray tandem mass spectrometry (HPLC-ESI-MS/MS).
Methods Mol Biol Volume: 603 Page(s): 307 - 315
01/01/2010 Authors: Molinaro RJ; Ritchie JC -
Zolpidem (Ambien) in pregnancy: placental passage and outcome.
Arch Womens Ment Health Volume: 12 Page(s): 441 - 446
12/01/2009 Authors: Juric S; Newport DJ; Ritchie JC; Galanti M; Stowe ZN -
A Routine UPLC-LC/MS/MS Assay for the Newer Antidepressants
Volume: 31 Page(s): 646 - 646
10/01/2009 Authors: Ritchie JC; Glover B; Ramsey C -
Multi-center evaluation of the CMV IgG assay on the family of Access (R) immunoassay systems from Beckman Coulter
Volume: 46 Page(s): S52 - S52
09/01/2009 Authors: Grangeot-Keros L; Gaidot N; Rawlins M; Flecheux O; Ritchie JC; Darte C; Bouniort F; Olson MD -
D-Dimer Assay Adaptation on an Automated Chemistry Analyzer to Reduce Turnaround Times
Volume: 132 Page(s): 462 - 463
09/01/2009 Authors: Chin AC; Brierre F; Fantz CR; Ritchie JC -
Venlafaxine in human breast milk and nursing infant plasma: determination of exposure.
J Clin Psychiatry Volume: 70 Page(s): 1304 - 1310
09/01/2009 Authors: Newport DJ; Ritchie JC; Knight BT; Glover BA; Zach EB; Stowe ZN -
Validation of a Novel Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry Method for Direct Monitoring of Argatroban Anticoagulation
Volume: 132 Page(s): 469 - 469
09/01/2009 Authors: Snyder ML; Winkler AM; Brierre F; Fantz CR; Ritchie JC; Molinaro RJ -
Effects of a cognitive stress challenge on myocardial perfusion and plasma cortisol in coronary heart disease patients with depression.
Stress Health Volume: 25 Page(s): 267 - 278
08/01/2009 Authors: Bremner JD; Cheema FA; Ashraf A; Afzal N; Fani N; Reed L; Musselman DL; Ritchie JC; Faber T; Votaw JR -
Therapeutic drug monitoring of plasma busulfan concentration by liquid chromatography-electrospray-tandem mass spectrometry (HPLC-ESI-MS/MS) in comparison with an established gas chromatography (GC-ECD) method
Volume: 55 Page(s): A263 - A263
06/01/2009 Authors: Snyder ML; Ritchie JC -
Performance Characteristics of Three Cytomegalovirus (CMV) Immunoglobulin G (IgG) Assays
Volume: 55 Page(s): A137 - A138
06/01/2009 Authors: Rawlins ML; La'ulu SL; Maxweil L; Ritchie JC; Roberts WL -
Adaptation of a D-Dimer Assay on an Automated High-Throughput Chemistry Analyzer to Reduce Turn-Around Times
Volume: 55 Page(s): A82 - A82
06/01/2009 Authors: Chin AC; Fantz CR; Ritchie JC -
Antidepressant drugs with differing pharmacological actions decrease activity of locus coeruleus neurons.
Int J Neuropsychopharmacol Volume: 12 Page(s): 627 - 641
06/01/2009 Authors: West CHK; Ritchie JC; Boss-Williams KA; Weiss JM -
Common genetic contributions to depressive symptoms and inflammatory markers in middle-aged men: the Twins Heart Study.
Psychosom Med Volume: 71 Page(s): 152 - 158
02/01/2009 Authors: Su S; Miller AH; Snieder H; Bremner JD; Ritchie J; Maisano C; Jones L; Murrah NV; Goldberg J; Vaccarino V -
Association of major depressive disorder with serum myeloperoxidase and other markers of inflammation: a twin study.
Biol Psychiatry Volume: 64 Page(s): 476 - 483
09/15/2008 Authors: Vaccarino V; Brennan M-L; Miller AH; Bremner JD; Ritchie JC; Lindau F; Veledar E; Su S; Murrah NV; Jones L -
Genetic and environmental influences on systemic markers of inflammation in middle-aged male twins.
Atherosclerosis Volume: 200 Page(s): 213 - 220
09/01/2008 Authors: Su S; Snieder H; Miller AH; Ritchie J; Bremner JD; Goldberg J; Dai J; Jones L; Murrah NV; Zhao J -
A novel liquid chromatography-tandem mass spectrometry method for assessing renal function
Volume: 130 Page(s): 472 - 472
09/01/2008 Authors: Molinaro RJ; Ritchie JC -
Lamotrigine in breast milk and nursing infants: determination of exposure.
Pediatrics Volume: 122 Page(s): e223 - e231
07/01/2008 Authors: Newport DJ; Pennell PB; Calamaras MR; Ritchie JC; Newman M; Knight B; Viguera AC; Liporace J; Stowe ZN -
Assessing renal function using a novel liquid chromatography-tandem mass spectrometry method for iothalamate identification and quantitation
Volume: 54 Page(s): A209 - A209
06/01/2008 Authors: Molinaro RJ; Ritchie JC -
Lamotrigine in pregnancy: clearance, therapeutic drug monitoring, and seizure frequency.
Neurology Volume: 70 Page(s): 2130 - 2136
05/27/2008 Authors: Pennell PB; Peng L; Newport DJ; Ritchie JC; Koganti A; Holley DK; Newman M; Stowe ZN -
In vitro antidepressant effects on the enhanced platelet activation of patients with major depressive disorder
Volume: 63 Page(s): 202S - 202S
04/01/2008 Authors: Bruce EC; Marzec U; Oliver LD; Schmotzer B; Manatunga AK; Ritchie JC; Nemeroff CB; Musselman DL -
Predictors of neonatal hypothalamic-pituitary-adrenal axis activity at delivery in women with psychiatric illness
Volume: 63 Page(s): 231S - 231S
04/01/2008 Authors: Smith AK; Katz ER; Newport DJ; Brennan PA; Ritchie JC; Ashe MR; Nemeroff CB; Cubells JF; Stowe ZN -
Connective tissue activation: I. The nature, specificity, measurement and distribution of connective tissue activating peptide.
Arthritis Rheum Volume: 58 Page(s): S39 - S52
02/01/2008 Authors: Castor CW -
PLACENTAL PASSAGE OF ANTIEPILEPTIC DRUGS: DETERMINANTS OF FETAL EXPOSURE
Volume: 49 Page(s): 109 - 110
01/01/2008 Authors: Whitfield TL; Stowe ZN; Holley DK; Newport DJ; Newman ML; Ritchie JC; Knight BT; Koganti A; Pennell PB -
SEIZURE CONTROL DURING PREGNANCY: POTENTIAL INFLUENCE OF 17 beta-ESTRADIOL AND PROGESTERONE
Volume: 49 Page(s): 119 - 119
01/01/2008 Authors: Pennell PB; Ritchie JC; Newman ML; Whitfield TL; Montgomery J; Pennell KD; Stowe ZN -
Assessing renal function using a novel liquid chromatography-tandem mass spectrometry method for iothalamate identification and quantitation
Volume: 128 Page(s): 510 - 510
09/01/2007 Authors: Molinaro RJ; Ritchie JC -
Intracellular protein expression patterns of glioblastomas, meningiomas and metastatic brain tumors using surface-enhanced laser desorption ionization mass spectroscopy (SELDI-TOF-MS)
Volume: 53 Page(s): A105 - A105
06/01/2007 Authors: Sanii LS; Hunter S; Schmotzer B; Jolly A; Ritchie J -
Identification and quantitation of lothalamate to assess renal function using liquid chromatography-tandem mass spectrometry
Volume: 53 Page(s): A92 - A92
06/01/2007 Authors: Molinaro RJ; Ritchie JC -
Three-way method comparison and validation study of a newly available intact parathyroid hormone assay
Volume: 53 Page(s): A198 - A198
06/01/2007 Authors: Molinaro RJ; Atha B; Ritchie JC; Koch DD -
Common genetic and environmental contributions to depression and inflammatory markers in middle-aged men: The twins heart study
Volume: 115 Page(s): E216 - E216
02/27/2007 Authors: Su S; Miller AH; Snieder H; Lee F; Bremner JD; Ritchie J; Maisano C; Buckham R; Jones L; Murrah N -
Lithium in breast milk and nursing infants: clinical implications.
Volume: 164 Page(s): 342 - 345
02/01/2007 Authors: Viguera AC; Newport DJ; Ritchie J; Stowe Z; Whitfield T; Mogielnicki J; Baldessarini RJ; Zurick A; Cohen LS -
Proteomic analysis of cerebrospinal fluid discriminates malignant and nonmalignant disease of the central nervous system and identifies specific protein markers.
Proteomics Volume: 6 Page(s): 6277 - 6287
12/01/2006 Authors: Khwaja FW; Nolen JDL; Mendrinos SE; Lewis MM; Olson JJ; Pohl J; Van Meir EG; Ritchie JC; Brat DJ -
Genetic and environmental influences on inflammatory markers: A study of middle-aged male twins
Volume: 114 Page(s): 839 - 839
10/31/2006 Authors: Su S; Snieder H; Miller AH; Ritchie J; Bremner JD; Goldberg J; Maisano C; Jones L; Murrah N; Zhao J -
Therapeutic drug monitoring of psychoactive drugs during pregnancy in the genomic era: challenges and opportunities.
J Psychopharmacol Volume: 20 Page(s): 54 - 59
07/01/2006 Authors: DeVane CL; Stowe ZN; Donovan JL; Newport DJ; Pennell PB; Ritchie JC; Owens MJ; Wang J-S -
Proteomics: a new diagnostic frontier.
Clin Chem Volume: 52 Page(s): 1218 - 1222
07/01/2006 Authors: Hortin GL; Jortani SA; Ritchie JC; Valdes R; Chan DW -
Preanalytical variables in coagulation testing.
Blood Coagul Fibrinolysis Volume: 17 Page(s): 425 - 426
07/01/2006 Authors: Sheppard CA; Channell C; Ritchie JC; Duncan A -
Inter-laboratory comparison of serum Lamotrigine methods
Volume: 52 Page(s): A69 - A69
06/01/2006 Authors: Ritchie JC; Berry D; Dugaw K; McMillin G; Wilson J -
Effect of hemolysis on samples submitted for coagulation studies
Volume: 52 Page(s): A23 - A23
06/01/2006 Authors: Kossover C; Ritchie JC; Fantz CR -
Analytical interference from Lymphazurin (TM) (isosulfan blue) Lymphatic dye on common clinical chemistry analytes
Volume: 52 Page(s): A108 - A109
06/01/2006 Authors: Sanii LS; Ritchie JC; Koch DD -
Pharmacokinetics of lamotrigine excretion into human breast milk
Volume: 66 Page(s): A72 - A73
03/14/2006 Authors: Pennell PB; Ritchie JC; Newport DJ; Liporace J; Montgomery JQ; Newman M; Stowe ZN -
Placental passage of tricyclic antidepressants.
Biol Psychiatry Volume: 59 Page(s): 287 - 290
02/01/2006 Authors: Loughhead AM; Stowe ZN; Newport DJ; Ritchie JC; DeVane CL; Owens MJ -
Neuropsychological impairment in bipolar disorder: the relationship with glucocorticoid receptor function.
Bipolar Disord Volume: 8 Page(s): 85 - 90
02/01/2006 Authors: Watson S; Thompson JM; Ritchie JC; Nicol Ferrier I; Young AH -
Antidepressants in amniotic fluid: another route of fetal exposure.
Am J Psychiatry Volume: 163 Page(s): 145 - 147
01/01/2006 Authors: Loughhead AM; Fisher AD; Newport DJ; Ritchie JC; Owens MJ; DeVane CL; Stowe ZN -
Pregnancy-induced alterations in oxcarbazepine (MHD) clearance and placental passage
Volume: 47 Page(s): 160 - 161
01/01/2006 Authors: Holley DK; Pennell PB; Newport DJ; Ritchie JC; Newman ML; Stowe ZN -
Relation of low socioeconomic status to C-reactive protein in patients with coronary heart disease (from the heart and soul study).
Am J Cardiol Volume: 96 Page(s): 1506 - 1511
12/01/2005 Authors: Lubbock LA; Goh A; Ali S; Ritchie J; Whooley MA -
Lithium placental passage and obstetrical outcome: implications for clinical management during late pregnancy.
Am J Psychiatry Volume: 162 Page(s): 2162 - 2170
11/01/2005 Authors: Newport DJ; Viguera AC; Beach AJ; Ritchie JC; Cohen LS; Stowe ZN -
Sex-related elevation in cortisol during chronic treatment with alprazolam associated with enhanced cognitive performance.
Psychopharmacology (Berl) Volume: 182 Page(s): 414 - 419
11/01/2005 Authors: Pomara N; Willoughby LM; Ritchie JC; Sidtis JJ; Greenblatt DJ; Nemeroff CB -
Cytologic findings and protein expression profiles associated with ductal carcinoma of the breast in ductal lavage specimens using surface-enhanced laser desorption and ionization-time of flight mass spectrometry.
Cancer Volume: 105 Page(s): 178 - 183
06/25/2005 Authors: Mendrinos S; Nolen JDL; Styblo T; Carlson G; Pohl J; Lewis M; Ritchie J -
Steady-state serum concentrations of progesterone following continuous intravenous infusion in patients with acute moderate to severe traumatic brain injury.
J Clin Pharmacol Volume: 45 Page(s): 640 - 648
06/01/2005 Authors: Wright DW; Ritchie JC; Mullins RE; Kellermann AL; Denson DD -
Testing the hypothesis that locus coeruleus hyperactivity produces depression-related changes via galanin.
Neuropeptides Volume: 39 Page(s): 281 - 287
06/01/2005 Authors: Weiss JM; Boss-Williams KA; Moore JP; Demetrikopoulos MK; Ritchie JC; West CHK -
Mechanisms mediating the effects of stress and depression on myocardial dysfunction
Volume: 57 Page(s): 150S - 150S
04/15/2005 Authors: Bremner JD; Cheema FA; Ashraf A; Afzal N; Fani N; Reed L; Musselman DL; Ritchie JC; Faber T; Votaw JR -
Aberrant thyroid testing results in a clinically euthyroid patient who had received a tumor vaccine.
Clin Chem Volume: 51 Page(s): 673 - 675
03/01/2005 Authors: Choi WWL; Srivatsa S; Ritchie JC -
Effects of a cognitive stress challenge on myocardial perfusion and plasma cortisol in coronary heart disease patients with and without a history of depression and psychological trauma
DEPRESSION AND ANXIETY Volume: 22 Page(s): 198 - 199
01/01/2005 Authors: Bremner JD; Cheema FA; Ashraf A; Afzal N; Fani N; Reed L; Musselman DL; Ritchie JC; Faber T; Votaw JR -
Hypothalamic-pituitary-adrenal axis function in patients with bipolar disorder.
Br J Psychiatry Volume: 184 Page(s): 496 - 502
06/01/2004 Authors: Watson S; Gallagher P; Ritchie JC; Ferrier IN; Young AH -
Evaluation of the Microgenics CEDIA (R) Cyclosporine Plus assay on the Beckman Coulter SYNCHRON LX (R) 20 clinical system.
Volume: 50 Page(s): A131 - A131
06/01/2004 Authors: Ritchie JC; Tuten T; Zhang W; Maxwell L -
Interdose elevation in plasma cortisol during chronic treatment with alprazolam but not lorazepam in the elderly.
Neuropsychopharmacology Volume: 29 Page(s): 605 - 611
03/01/2004 Authors: Pomara N; Willoughby LM; Ritchie JC; Sidtis JJ; Greenblatt DJ; Nemeroff CB -
A novel system for the determination of antidepressant concentrations in human breast milk.
Ther Drug Monit Volume: 26 Page(s): 47 - 52
02/01/2004 Authors: Hostetter AL; Stowe ZN; Cox M; Ritchie JC -
Defining fetal exposure to lamotrigine
Volume: 45 Page(s): 233 - 233
01/01/2004 Authors: Pennell PB; Ritchie JC; Newport DJ; Koganti A; Beach AJ; Newman M; Stowe ZN -
Analysis and classification of proteomic profiles in breast cancer via a combined cytology/SELDI-TOF technique.
Volume: 49 Page(s): A14 - A14
06/01/2003 Authors: Nolen JL; Mendrinos S; Skountzou I; Ritchie JC; Lewis MM -
Cerebrospinal fluid corticotropin-releasing factor (CRF) and vasopressin concentrations predict pituitary response in the CRF stimulation test: a multiple regression analysis.
Neuropsychopharmacology Volume: 28 Page(s): 569 - 576
03/01/2003 Authors: Newport DJ; Heim C; Owens MJ; Ritchie JC; Ramsey CH; Bonsall R; Miller AH; Nemeroff CB -
The pharmacokinetics of sertraline excretion into human breast milk: determinants of infant serum concentrations.
J Clin Psychiatry Volume: 64 Page(s): 73 - 80
01/01/2003 Authors: Stowe ZN; Hostetter AL; Owens MJ; Ritchie JC; Sternberg K; Cohen LS; Nemeroff CB -
Action of three ectopeptidases on corticotropin-releasing factor: metabolism and functional aspects.
Neuropsychopharmacology Volume: 28 Page(s): 22 - 33
01/01/2003 Authors: Ritchie JC; Davis TP; Nemeroff CB -
Feasibility of proteomic evaluation of ductal lavage fluid for breast diseases
BREAST CANCER RESEARCH AND TREATMENT Volume: 82 Page(s): S175 - S176
01/01/2003 Authors: Fournier KF; Mendrinos SE; Ritchie J; Lewis M; Vlahoua A; Gregory B; Schiller A; Perry RR; Wright G; Semmes OJ -
Pre-filtration oxygenation abrogates the leukoreduction filtration lesion in hemoglobin AS whole blood units.
Volume: 100 Page(s): 287A - 287A
11/16/2002 Authors: Hillyer KL; Rapaport HJ; Roback JD; Ritchie JC; Hillyer CD -
Platelet monoamine oxidase, smoking cessation, and tobacco withdrawal symptoms.
Nicotine Tob Res Volume: 3 Page(s): 383 - 390
11/01/2001 Authors: Rose JE; Behm FM; Ramsey C; Ritchie JC -
Comparison of five assays for homocysteine.
CLINICAL CHEMISTRY Volume: 47 Page(s): A214 - A214
06/01/2001 Authors: Ritchie JC; Mullins RE; Benson E; Davis T -
Paroxetine in breast milk - Dr. Stowe and colleagues reply
AMERICAN JOURNAL OF PSYCHIATRY Volume: 158 Page(s): 144 - 145
01/01/2001 Authors: Stowe ZN; Cohen LS; Ritchie JC; Owens MJ; Nemeroff CB -
Paroxetine in breast milk.
Am J Psychiatry Volume: 158 Page(s): 144 - 145
01/01/2001 Authors: Wisner KL; Findling RL; Perel JM -
Amniotic fluid and umbilical cord blood concentrations of antidepressants in three women.
Biol Psychiatry Volume: 48 Page(s): 1032 - 1034
11/15/2000 Authors: Hostetter A; Ritchie JC; Stowe ZN -
Regional differences in brain monoamine oxidase subtypes in an animal model of geriatric depression: effects of olfactory bulbectomy in young versus aged rats.
Brain Res Volume: 882 Page(s): 149 - 154
11/03/2000 Authors: Slotkin TA; Seidler FJ; Ritchie JC -
In vivo and in vitro induction of human cytochrome P4503A4 by dexamethasone.
Clin Pharmacol Ther Volume: 68 Page(s): 356 - 366
10/01/2000 Authors: McCune JS; Hawke RL; LeCluyse EL; Gillenwater HH; Hamilton G; Ritchie J; Lindley C -
Dexamethasone metabolism in dexamethasone suppression test suppressors and nonsuppressors.
Biol Psychiatry Volume: 47 Page(s): 677 - 680
04/01/2000 Authors: Cassidy F; Ritchie JC; Verghese K; Carroll BJ -
Paroxetine in human breast milk and nursing infants.
Am J Psychiatry Volume: 157 Page(s): 185 - 189
02/01/2000 Authors: Stowe ZN; Cohen LS; Hostetter A; Ritchie JC; Owens MJ; Nemeroff CB -
Retrospective analysis of sequential changes in serum intact parathyroid hormone levels during conventional parathyroid exploration.
Surgery Volume: 126 Page(s): 1139 - 1143
12/01/1999 Authors: Weber CJ; Ritchie JC -
Integrating pharmacy & laboratory practice
Volume: 45 Page(s): S36 - S36
06/01/1999 Authors: Ritchie JC -
Effects of aging and glucocorticoid treatment on monoamine oxidase subtypes in rat cerebral cortex: therapeutic implications.
Brain Res Bull Volume: 47 Page(s): 345 - 348
11/01/1998 Authors: Slotkin TA; Seidler FJ; Ritchie JC -
Atypical antipsychotic drugs selectively increase neurotensin efflux in dopamine terminal regions.
Proc Natl Acad Sci U S A Volume: 95 Page(s): 11462 - 11464
09/15/1998 Authors: Radke JM; Owens MJ; Ritchie JC; Nemeroff CB -
Evaluation of the COBAS (R) INTEGRA for routine lipid testing.
CLINICAL CHEMISTRY Volume: 44 Page(s): A78 - A79
06/01/1998 Authors: Ritchie JC; Tuten T; Jerkunica I; Zhang H; Sgoutas DS; Mullins RE -
Evaluation of the DAU lysergic acid diethylamide (LSD) assay on the COBAS (R) INTEGRA.
CLINICAL CHEMISTRY Volume: 44 Page(s): A86 - A86
06/01/1998 Authors: Ritchie JC; Mullins RE; Tuten T; Zhang H; Jerkunica I -
Plasma dexamethasone concentration and cortisol response during manic episodes.
Biol Psychiatry Volume: 43 Page(s): 747 - 754
05/15/1998 Authors: Cassidy F; Ritchie JC; Carroll BJ -
HbA1c measurements by immunoassay on the COBAS(R) INTEGRA.
CLINICAL CHEMISTRY Volume: 43 Page(s): 219 - 219
06/01/1997 Authors: Mullins RE; Jerkunica I; Ritchie JC; Tuten T -
Evaluation of the COBAS(R) INTEGRA for drugs of abuse testing.
CLINICAL CHEMISTRY Volume: 43 Page(s): 516 - 516
06/01/1997 Authors: Ritchie JC; Tuten T; Jerkunica I; Zhang H; Mullins RE -
Serotonin transporter expression in rat brain regions and blood platelets: aging and glucocorticoid effects.
Biol Psychiatry Volume: 41 Page(s): 172 - 183
01/15/1997 Authors: Slotkin TA; McCook EC; Ritchie JC; Carroll BJ; Seidler FJ -
Do glucocorticoids contribute to the abnormalities in serotonin transporter expression and function seen in depression? An animal model.
Biol Psychiatry Volume: 40 Page(s): 576 - 584
10/01/1996 Authors: Slotkin TA; McCook EC; Ritchie JC; Seidler FJ -
Use of site-specified tritium labelling to confirm the formation of 17-oxosparteine as a minor urinary metabolite of sparteine in man.
Xenobiotica Volume: 26 Page(s): 977 - 982
09/01/1996 Authors: Ritchie JC; Mitchell SC; Smith RL; Zhang AQ -
Apolipoprotein E-epsilon 4 frequency in geriatric depression.
Biol Psychiatry Volume: 40 Page(s): 69 - 71
07/01/1996 Authors: Krishnan KR; Tupler LA; Ritchie JC; McDonald WM; Knight DL; Nemeroff CB; Carroll BJ -
Modification of the Bio Rad tricyclic antidepressant methodology to measure the serotonin reuptake inhibitors.
CLINICAL CHEMISTRY Volume: 42 Page(s): 527 - 527
06/01/1996 Authors: Ritchie JC; Zhang W -
Serum prolactin, electrode placement, and the convulsive threshold during ECT.
Convuls Ther Volume: 12 Page(s): 81 - 85
06/01/1996 Authors: McCall WV; Weiner RD; Carroll BJ; Shelp FE; Ritchie JC; Austin S; Norris J -
Cognitive impairment in elderly depressed individuals with APOE epsilon 4
BIOLOGICAL PSYCHIATRY Volume: 39 Page(s): 539 - 539
04/01/1996 Authors: Tupler LA; Krishnan KRR; Ritchie JC; McDonald WM; Knight DL; Nemeroff CB; Carroll BJ -
Differential effects of alprazolam and lorazepam on plasma cortisol in normal elderly
BIOLOGICAL PSYCHIATRY Volume: 39 Page(s): 428 - 428
04/01/1996 Authors: Pomara N; Deptula D; Nolan K; Tun H; Singh R; Leviste F; Ritchie J; Greenblatt DJ; Nemeroff CB -
Sparteine metabolism in a Nigerian population.
Drug Metabol Drug Interact Volume: 13 Page(s): 129 - 135
01/01/1996 Authors: Ritchie JC; Mitchell SC; Smith RL -
Benzodiazepine sensitivity in panic disorder: effects of chronic alprazolam treatment.
Neuropsychopharmacology Volume: 12 Page(s): 147 - 157
04/01/1995 Authors: Cowley DS; Roy-Byrne PP; Radant A; Ritchie JC; Greenblatt DJ; Nemeroff CB; Hommer DW -
Cortisol responses following placebo and alcohol in Asians with different ALDH2 genotypes.
J Stud Alcohol Volume: 55 Page(s): 207 - 213
03/01/1994 Authors: Wall TL; Nemeroff CB; Ritchie JC; Ehlers CL -
A pilot study of a structured interview addressing sexual function in men with schizophrenia.
Biol Psychiatry Volume: 35 Page(s): 32 - 35
01/01/1994 Authors: Burke MA; McEvoy JP; Ritchie JC -
PREMORBID SUSCEPTIBILITY TO ANXIETY AND EXCESS DOPAMINERGIC ACTIVITY ARE ASSOCIATED WITH THE DEVELOPMENT OF DELIRIUM IN THE INTENSIVE-CARE UNIT
Volume: 147 Page(s): A109 - A109
04/01/1993 Authors: BROWN TM; RITCHIE JC; HOLMES VF; OXLEY SL; WILLIAMS R; KUSSIN P -
The dexamethasone suppression test and quantitative cerebral anatomy in depression.
Biol Psychiatry Volume: 33 Page(s): 442 - 449
03/15/1993 Authors: Coffey CE; Wilkinson WE; Weiner RD; Ritchie JC; Aque M -
PHARMACOKINETIC AND PHARMACODYNAMIC MODELING OF DEXAMETHASONE IN NORMAL CONTROLS AND NONDEPRESSED AND DEPRESSED-PATIENTS
CLINICAL PHARMACOLOGY & THERAPEUTICS Volume: 53 Page(s): 186 - 186
02/01/1993 Authors: GUPTA SK; RITCHIE JC; OSULLIVAN B; JOHNSON GF -
Dose response relationship between plasma ACTH and cortisol after the infusion of ACTH1-24.
Eur Arch Psychiatry Clin Neurosci Volume: 242 Page(s): 240 - 243
01/01/1993 Authors: Krishnan KR; Miller MN; Helms MJ; Reed D; Ritchie JC; Nemeroff CB; Carroll BJ -
Rhythmicity and response to A.M. and P.M. CRH challenge in elderly subjects.
Neurobiol Aging Volume: 14 Page(s): 101 - 106
01/01/1993 Authors: Blazer DG; Malmrose LC; Wallsten SM; Nemeroff CB; Reed DA; Ritchie JC; Tyrey ME -
Preliminary studies of 6 beta-hydroxydexamethasone and its importance in the DST.
Biol Psychiatry Volume: 32 Page(s): 825 - 833
11/01/1992 Authors: Ritchie JC; Owens MJ; Mayer H; Watson JT; Kilts C; Carroll BJ -
In vivo assessment of pituitary volume with magnetic resonance imaging and systematic stereology: relationship to dexamethasone suppression test results in patients.
Psychiatry Res Volume: 44 Page(s): 63 - 70
10/01/1992 Authors: Axelson DA; Doraiswamy PM; Boyko OB; Rodrigo Escalona P; McDonald WM; Ritchie JC; Patterson LJ; Ellinwood EH; Nemeroff CB; Krishnan KR -
5 alpha-pregnane-3 alpha, 21-diol-20-one (THDOC) attenuates mild stress-induced increases in plasma corticosterone via a non-glucocorticoid mechanism: comparison with alprazolam.
Brain Res Volume: 573 Page(s): 353 - 355
02/28/1992 Authors: Owens MJ; Ritchie JC; Nemeroff CB -
RU486 in depression.
Prog Neuropsychopharmacol Biol Psychiatry Volume: 16 Page(s): 913 - 920
01/01/1992 Authors: Krishnan KR; Reed D; Wilson WH; Saunders WB; Ritchie JC; Nemeroff CB; Carroll BJ -
Modeling the pharmacokinetics and pharmacodynamics of dexamethasone in depressed patients.
Eur J Clin Pharmacol Volume: 43 Page(s): 51 - 55
01/01/1992 Authors: Gupta SK; Ritchie JC; Ellinwood EH; Wiedemann K; Holsboer F -
Human immunodeficiency virus glycoprotein (gp120) infused into rat brain induces interleukin 1 to elevate pituitary-adrenal activity and decrease peripheral cellular immune responses.
Proc Natl Acad Sci U S A Volume: 88 Page(s): 11246 - 11250
12/15/1991 Authors: Sundar SK; Cierpial MA; Kamaraju LS; Long S; Hsieh S; Lorenz C; Aaron M; Ritchie JC; Weiss JM -
Levels of urinary free cortisol in social phobia.
J Clin Psychiatry Volume: 52 Suppl Page(s): 41 - 42
11/01/1991 Authors: Potts NL; Davidson JR; Krishnan KR; Doraiswamy PM; Ritchie JC -
Neuroendocrine effects of diazepam in panic and generalized anxiety disorders.
Biol Psychiatry Volume: 30 Page(s): 73 - 80
07/01/1991 Authors: Roy-Byrne PP; Cowley DS; Hommer D; Ritchie J; Greenblatt D; Nemeroff C -
Muscimol injections into the median raphe nucleus increase serum ACTH and corticosterone concentrations via a nonserotonergic mechanism.
Pharmacol Biochem Behav Volume: 39 Page(s): 765 - 768
07/01/1991 Authors: Paris JM; Lorens SA; Lee JM; Mitsushio H; Ritchie JC; Nemeroff CB -
Alterations in the hypothalamic-pituitary-adrenal axis in a proposed animal model of depression with genetic muscarinic supersensitivity.
Neuropsychopharmacology Volume: 4 Page(s): 87 - 93
02/01/1991 Authors: Owens MJ; Overstreet DH; Knight DL; Rezvani AH; Ritchie JC; Bissette G; Janowsky DS; Nemeroff CB -
The 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane stimulates the hypothalamic-pituitary-adrenal (HPA) axis. II. Biochemical and physiological evidence for the development of tolerance after chronic administration.
J Pharmacol Exp Ther Volume: 256 Page(s): 795 - 800
02/01/1991 Authors: Owens MJ; Knight DL; Ritchie JC; Nemeroff CB -
The 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane stimulates the hypothalamic-pituitary-adrenal (HPA) axis. I. Acute effects on HPA axis activity and corticotropin-releasing factor-containing neurons in the rat brain.
J Pharmacol Exp Ther Volume: 256 Page(s): 787 - 794
02/01/1991 Authors: Owens MJ; Knight DL; Ritchie JC; Nemeroff CB -
Effects of interleukin-1 infused into brain are antagonized by alpha-MSH in a dose-dependent manner.
Eur J Pharmacol Volume: 192 Page(s): 177 - 179
01/03/1991 Authors: Weiss JM; Sundar SK; Cierpial MA; Ritchie JC -
Fast feedback regulation of ACTH by cortisol.
Prog Neuropsychopharmacol Biol Psychiatry Volume: 15 Page(s): 523 - 529
01/01/1991 Authors: Krishnan KR; Ritchie JC; Manepalli AN; Saunders W; Li SW; Venkataraman S; Nemeroff CB; Carroll BJ -
Role of serotonin in hypothalamo pituitary adrenal axis escape from dexamethasone suppression.
Prog Neuropsychopharmacol Biol Psychiatry Volume: 15 Page(s): 637 - 642
01/01/1991 Authors: Krishnan KR; Ritchie JC; Manepalli AN; Wilson WH; Saunders WB; Venkataraman SS; Carroll BJ -
Brain IL-1-induced immunosuppression occurs through activation of both pituitary-adrenal axis and sympathetic nervous system by corticotropin-releasing factor.
J Neurosci Volume: 10 Page(s): 3701 - 3706
11/01/1990 Authors: Sundar SK; Cierpial MA; Kilts C; Ritchie JC; Weiss JM -
Nocturnal and early morning secretion of ACTH and cortisol in humans.
Biol Psychiatry Volume: 28 Page(s): 47 - 57
07/01/1990 Authors: Krishnan KR; Ritchie JC; Saunders W; Wilson W; Nemeroff CB; Carroll BJ -
Determination of plasma dexamethasone by chemical oxidation and electron capture negative ionization mass spectrometry.
Biomed Environ Mass Spectrom Volume: 19 Page(s): 341 - 347
06/01/1990 Authors: Kayganich K; Watson JT; Kilts C; Ritchie J -
Adrenocortical sensitivity to low-dose ACTH administration in depressed patients.
Biol Psychiatry Volume: 27 Page(s): 930 - 933
04/15/1990 Authors: Krishnan KR; Ritchie JC; Saunders WB; Nemeroff CB; Carroll BJ -
Plasma dexamethasone concentrations and the dexamethasone suppression test.
Biol Psychiatry Volume: 27 Page(s): 159 - 173
01/15/1990 Authors: Ritchie JC; Belkin BM; Krishnan KR; Nemeroff CB; Carroll BJ -
Differential diagnosis and pathophysiology of Cushing's syndrome and primary affective disorder.
J Neuropsychiatry Clin Neurosci Volume: 2 Page(s): 34 - 43
01/01/1990 Authors: Krystal A; Krishnan KR; Raitiere M; Poland R; Ritchie JC; Dunnick NR; Hanada K; Nemeroff CB -
Pharmacokinetics of growth hormone secretion in humans induced by growth hormone releasing hormone.
Life Sci Volume: 47 Page(s): 1887 - 1893
01/01/1990 Authors: Gupta SK; Krishnan RR; Ellinwood EH; Ritchie JC; Nemeroff CB -
Growth hormone response to growth hormone releasing factor in Alzheimer's disease.
Neuroendocrinology Volume: 50 Page(s): 663 - 666
12/01/1989 Authors: Nemeroff CB; Krishnan KR; Belkin BM; Ritchie JC; Clark C; Vale WW; Rivier JE; Thorner MO -
The corticotropin-releasing hormone test in patients with posttraumatic stress disorder.
Biol Psychiatry Volume: 26 Page(s): 349 - 355
08/01/1989 Authors: Smith MA; Davidson J; Ritchie JC; Kudler H; Lipper S; Chappell P; Nemeroff CB -
Intracerebroventricular infusion of interleukin 1 rapidly decreases peripheral cellular immune responses.
Proc Natl Acad Sci U S A Volume: 86 Page(s): 6398 - 6402
08/01/1989 Authors: Sundar SK; Becker KJ; Cierpial MA; Carpenter MD; Rankin LA; Fleener SL; Ritchie JC; Simson PE; Weiss JM -
Plasma corticosterone in dexamethasone suppression test on depressed patients.
Proc Chin Acad Med Sci Peking Union Med Coll Volume: 4 Page(s): 72 - 79
01/01/1989 Authors: Li SW; Ritchie JC; Carroll BJ -
Depression in early-onset Alzheimer's disease: clinical and neuroendocrine correlates.
Biol Psychiatry Volume: 24 Page(s): 937 - 940
12/01/1988 Authors: Krishnan KR; Heyman A; Ritchie JC; Utley CM; Dawson DV; Rogers H -
Circadian rhythm of adrenergic regulation of adrenocorticotropin and cortisol secretion in man.
J Clin Endocrinol Metab Volume: 67 Page(s): 404 - 406
08/01/1988 Authors: Naylor MR; Krishnan KR; Manepalli AN; Ritchie JC; Wilson WH; Carroll BJ -
Adrenocortical sensitivity to ACTH in humans.
Biol Psychiatry Volume: 24 Page(s): 105 - 108
05/01/1988 Authors: Krishnan KR; Ritchie JC; Manepalli AN; Nemeroff CB; Carroll BJ -
One stressful event blocks multiple actions of diazepam for up to at least a month.
Brain Res Volume: 445 Page(s): 380 - 385
04/05/1988 Authors: Antelman SM; Knopf S; Kocan D; Edwards DJ; Ritchie JC; Nemeroff CB -
Growth hormone response to growth hormone-releasing factor in depression.
Peptides Volume: 9 Suppl 1 Page(s): 113 - 116
01/01/1988 Authors: Krishnan KR; Manepalli AN; Ritchie JC; Rayasam K; Melville ML; Thorner MO; Rivier JE; Vale WW; Nemeroff CB -
Growth hormone-releasing factor stimulation test in depression.
Am J Psychiatry Volume: 145 Page(s): 90 - 92
01/01/1988 Authors: Krishnan KR; Manepalli AN; Ritchie JC; Rayasam K; Melville ML; Daughtry G; Thorner MO; Rivier JE; Vale WW; Nemeroff CB -
Effects of gamma-interferon on the endocrine system: results from a phase I study.
Cancer Res Volume: 47 Page(s): 6397 - 6401
12/01/1987 Authors: Goldstein D; Gockerman J; Krishnan R; Ritchie J; Tso CY; Hood LE; Ellinwood E; Laszlo J -
Effect of gamma interferon on the hypothalamic-pituitary-adrenal system.
Biol Psychiatry Volume: 22 Page(s): 1163 - 1166
09/01/1987 Authors: Krishnan R; Ellinwood EH; Laszlo J; Hood L; Ritchie J -
THE ROLE OF EPINEPHRINE CONTAINING NEURONS IN THE HYPOTHALAMIC PARAVENTIRCULAR NUCLEUS IN THE REGULATION OF THE HPA AXIS
NEUROENDOCRINOLOGY LETTERS Volume: 9 Page(s): 177 - 177
06/01/1987 Authors: JOHNSON KL; ANDERSON CM; RITCHIE JC; KILTS CD -
COMPARISON OF PLASMA-CORTISOL DETERMINATIONS BY THE ABBOTT TDX AND CPB METHODOLOGY, FOR USE IN THE DEXAMETHASONE SUPPRESSION TEST (DST)
CLINICAL CHEMISTRY Volume: 33 Page(s): 959 - 959
06/01/1987 Authors: RITCHIE JC; KEGELMEYER AE; WALKER JT; CARROLL BJ; LONGHURST S -
OPTIMIZATION OF THE SOLID-PHASE EXTRACTION OF PLASMA CRH FOR SUBSEQUENT RIA ANALYSIS
NEUROENDOCRINOLOGY LETTERS Volume: 9 Page(s): 177 - 177
06/01/1987 Authors: LIU PK; BISSETTE G; RITCHIE JC -
PATTERNS OF HORMONE-SECRETION IN NORMAL VOLUNTEERS AND PSYCHIATRIC-PATIENTS
NEUROENDOCRINOLOGY LETTERS Volume: 9 Page(s): 155 - 155
06/01/1987 Authors: KRISHNAN KRR; NEMEROFF CB; MANEPALLI AH; VENKATARAMAN SS; RITCHIE JC; CARROLL BJ -
PHYSIOLOGY OF HUMAN HPA REGULATION IN DEPRESSION
INTERNATIONAL JOURNAL OF NEUROSCIENCE Volume: 32 Page(s): 458 - 459
01/01/1987 Authors: KRISHNAN KRR; CARROLL BJ; MANEPALLI AN; RITCHIE JC; NEMEROFF CB -
Alterations in corticotropin-releasing factor-like immunoreactivity in discrete rat brain regions after acute and chronic stress.
J Neurosci Volume: 6 Page(s): 2908 - 2914
10/01/1986 Authors: Chappell PB; Smith MA; Kilts CD; Bissette G; Ritchie J; Anderson C; Nemeroff CB -
The metabolism of debrisoquine in man: (1) regioselectivity of hydroxylation and (2) aberrant oxidative metabolism in two sibling patients with carbimazole-induced agranulocytosis.
Xenobiotica Volume: 16 Page(s): 503 - 509
05/01/1986 Authors: Ritchie JC; Crothers MJ; Shah RR; Idle JR; Smith RL -
Sulphoxidation of S-carboxymethyl-L-cysteine in the rhesus monkey (Macaca mulatta), cynomologus monkey (Macaca fascicularis), African green monkey (Cercopithecus aethiops) and the marmoset (Callithrix jacchus).
Comp Biochem Physiol B Volume: 84 Page(s): 143 - 144
01/01/1986 Authors: Mitchell SC; Waring RH; Wilson VL; Idle JR; Autrup H; Harris CC; Ritchie JC; Crothers MJ; Sieber SM -
Plasma cortisol determination for the dexamethasone suppression test. Comparison of competitive protein-binding and commercial radioimmunoassay methods.
Arch Gen Psychiatry Volume: 42 Page(s): 493 - 497
05/01/1985 Authors: Ritchie JC; Carroll BJ; Olton PR; Shively V; Feinberg M -
Metabolic oxidation phenotypes as markers for susceptibility to lung cancer.
Nature Volume: 312 Page(s): 169 - 170
11/08/1984 Authors: Ayesh R; Idle JR; Ritchie JC; Crothers MJ; Hetzel MR -
Comparison of plasma cortisol and corticosterone in the dexamethasone suppression test for melancholia.
Psychoneuroendocrinology Volume: 9 Page(s): 45 - 55
01/01/1984 Authors: Wilens TE; Ritchie JC; Carroll BJ -
The genetic control of sparteine and debrisoquine metabolism in man with new methods of analysing bimodal distributions.
J Med Genet Volume: 20 Page(s): 321 - 329
10/01/1983 Authors: Evans DA; Harmer D; Downham DY; Whibley EJ; Idle JR; Ritchie J; Smith RL -
Spectral binding studies of the polymorphically metabolized drugs debrisoquine, sparteine and phenformin by cytochrome P-450 of normal and hydroxylation deficient rat strains.
Biochem Pharmacol Volume: 31 Page(s): 3193 - 3199
10/15/1982 Authors: Kpfer A; Al-Dabbagh SG; Ritchie JC; Idle JR; Smith RL -
Interference by carbamazepine with the dexamethasone suppression test.
Biol Psychiatry Volume: 17 Page(s): 611 - 620
05/01/1982 Authors: Privitera MR; Greden JF; Gardner RW; Ritchie JC; Carroll BJ -
Population studies of polymorphism in drug oxidation and its relevance to carcinogenesis.
IARC Sci Publ Page(s): 381 - 394
01/01/1982 Authors: Ritchie JC; Idle JR -
Polymorphic 4-hydroxylation of debrisoquine in chronic discoid psoriasis.
Eur J Clin Pharmacol Volume: 21 Page(s): 257 - 258
01/01/1981 Authors: Chapman PH; Rawlins MD; Shuster S; Idle JR; Ritchie JC; Smith RL -
Plasma dexamethasone concentrations and cortisol suppression response in patients with endogenous depression.
J Clin Endocrinol Metab Volume: 51 Page(s): 433 - 437
09/01/1980 Authors: Carroll BJ; Schroeder K; Mukhopadhyay S; Greden JF; Feinberg M; Ritchie J; Tarika J -
Connective tissue activation. XVI. Detection of a human platelet-derived connective tissue activating peptide (CTAP-III) in human sera and plasma and in synovial fluids and tissues.
Proc Soc Exp Biol Med Volume: 164 Page(s): 267 - 274
07/01/1980 Authors: Sloan TB; Weiss JJ; Anderson B; Ritchie JC; Whitney SL; Castor CW -
Toxicological implications of polymorphic drug metabolism.
Ciba Found Symp Volume: 76 Page(s): 219 - 244
01/01/1980 Authors: Ritchie JC; Sloan TP; Idle JR; Smith RL -
Oxidation phenotype and metiamide metabolism [proceedings].
Br J Pharmacol Volume: 66 Page(s): 432P
07/01/1979 Authors: Idle JR; Ritchie JC; Smith RL -
Connective tissue activation. XIV. Composition and actions of a human platelet autacoid mediator.
Arthritis Rheum Volume: 22 Page(s): 260 - 272
03/01/1979 Authors: Castor CW; Ritchie JC; Williams CH; Scott ME; Whitney SL; Myers SL; Sloan TB; Anderson BE -
IDENTITY OF LOW AFFINITY PLATELET FACTOR-4 AND CONNECTIVE-TISSUE ACTIVATING PEPTIDE-III
FEDERATION PROCEEDINGS Volume: 37 Page(s): 260 - 260
01/01/1978 Authors: NIEWIAROWSKI S; CASTOR CW; RUCINSKI B; RITCHIE JC; SCOTT ME -
Measurement of urinary and serous-fluid glycosaminoglycans and urinary hydroxyproline.
Am J Clin Pathol Volume: 67 Page(s): 585 - 590
06/01/1977 Authors: Ritchie JC; Smith SF; Castor CW -
Connective tissue activation. XI. Stimulation of glycosaminoglycan and DNA formation by a platelet factor.
Arthritis Rheum Volume: 20 Page(s): 859 - 868
04/01/1977 Authors: Castor CW; Ritchie JC; Scott ME; Whitney SL -
CHARACTERISTICS OF A HUMAN PLATELET FACTOR WHICH STIMULATES DNA AND GLYCOSAMINOGLYCAN SYNTHESIS
CLINICAL RESEARCH Volume: 24 Page(s): A575 - A575
01/01/1976 Authors: CASTOR CW; SCOTT ME; RITCHIE JC; WHITNEY SL -
Connective tissue activation. VII. Evidence supporting a role for prostaglandins and cyclic nucleotides.
J Lab Clin Med Volume: 85 Page(s): 392 - 404
03/01/1975 Authors: Castor CW -
CONNECTIVE-TISSUE ACTIVATION - EVIDENCE FOR MULTIPLE CONNECTIVE-TISSUE ACTIVATING PEPTIDES
CLINICAL RESEARCH Volume: 23 Page(s): A527 - A527
01/01/1975 Authors: CASTOR CW; RITCHIE JC; WILLIAMS CH; OEGEMA TR -
Connective tissue activation. IX. Modification by pharmacologic agents.
Arthritis Rheum Volume: 18 Page(s): 451 - 460
01/01/1975 Authors: Castor CW -
Connective tissue activation. II. Abnormalities of cultured rheumatoid synovial cells.
Arthritis Rheum Volume: 14 Page(s): 55 - 66
01/01/1971 Authors: Castor CW -
Connective tissue activation. I. The nature, specificity, measurement and distribution of connective tissue activating peptide.
Arthritis Rheum Volume: 14 Page(s): 41 - 54
01/01/1971 Authors: Castor CW