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Profile

James Lah MD/PhD

  • Department of Neurology
    Professor
  • (404) 727-3509
  • jlah@emory.edu
Head shot of James Lah

Academic Appointment

  • Alice and Roy Richards Chair, Neurology, Emory University
  • Vice Chair, Neurology, Emory University
  • Associate Professor, Neurology, Emory University
  • Training Faculty, Graduate Division of Biological and Biomedical Sciences, Emory University
  • Training Faculty, Neuroscience Program, Emory University

Education

Degrees

  • BS from Duke University
  • MD-PhD from Ohio State University

Research

Focus

  • My research is driven by the goal of understanding basic pathogenic mechanisms in neurodegenerative disorders. Specific topics of interest include: regulation of amyloid precursor protein (APP) processing through control of intracellular trafficking, analysis of the role of the apolipoprotein E (ApoE) receptor LR11 in amyloidogenesis, modulation of APP processing by muscarinic receptor activity, and characterization of new genes involved in Alzheimers disease, Parkinsons disease, Frontotemporal Dementia, and other neurodegenerative disorders.

Publications

  • County Health Departments Facilitate Telehealth Dementia Evaluation: The Georgia Memory Net Collaboration.
    Telemed J E Health
    04/21/2025 Authors: Loring DW; Lah JJ; Head EN; Hale CL; McIntosh RL
  • The association between pulse wave velocity and cerebrospinal fluid biomarkers for Alzheimer's disease.
    J Alzheimers Dis Page(s): 13872877251331235
    04/21/2025 Authors: Kim H; Kulshreshtha A; Alonso A; Goldstein FC; Johnson EC; Gold ME; Quyyumi AA; Lah JJ
  • Proteomic Subtyping of Alzheimer's Disease CSF links Blood-Brain Barrier Dysfunction to Reduced levels of Tau and Synaptic Biomarkers.

    03/15/2025 Authors: Bangs MC; Gadhavi J; Carter EK; Ping L; Duong DM; Dammer EB; Wu F; Shantaraman A; Fox EJ; Johnson ECB
  • Probing locus coeruleus functional network in healthy aging and its association with Alzheimer's disease biomarkers using pupillometry.
    Alzheimers Res Ther Volume: 17 Page(s): 53
    02/27/2025 Authors: Wu J; Toporek A; Lin Q; Goldstein FC; Loring DW; Kelberman MA; Weinshenker D; Levey AI; Lah JJ; Qiu D
  • Accelerated model-based T1, T2* and proton density mapping using a Bayesian approach with automatic hyperparameter estimation.
    Magn Reson Med Volume: 93 Page(s): 563 - 583
    02/01/2025 Authors: Huang S; Lah JJ; Allen JW; Qiu D
  • Survival of Patients at a Neurology Clinic: No Improvement Over 12 Years.
    Alzheimer Dis Assoc Disord
    01/30/2025 Authors: Steenland K; Tan Y; Mullins SM; Kidd TE; Gong Q; Lah JJ
  • ABBA Letter Alternation: A telehealth inspired measure of executive functioning/inhibitory control.
    Clin Neuropsychol Page(s): 1 - 12
    01/09/2025 Authors: Loring DW; Hewitt KC; Drane DL; Zhao L; Xu H; Lah JJ; Goldstein FC
  • Stratifying risk of Alzheimer's disease in healthy middle-aged individuals with machine learning.
    Brain Commun Volume: 7 Page(s): fcaf121
    01/01/2025 Authors: Tandon R; Zhao L; Watson CM; Sarkar N; Elmor M; Heilman C; Sanders K; Hales CM; Yang H; Loring DW
  • CSF proteomics reveals changes in myelin and synaptic biology after Spectris treatment.
    Alzheimers Dement (N Y) Volume: 11 Page(s): e70051
    01/01/2025 Authors: Hajs M; Pandey K; Singer AC; Duong D; Bitarafan S; Shpokayte M; Malchano Z; Kern R; Lah JJ; Levey AI
  • Technology literacy and access to digital resources for remote assessment among adults enrolled in Alzheimer's disease research.
    J Alzheimers Dis Volume: 102 Page(s): 1286 - 1296
    12/01/2024 Authors: Okafor M; Yang Z; Vickers KL; Sanders K; Simama N; Hewitt KC; Lah J; Levey AI; Goldstein FC; Hajjar I
  • Receptive vocabulary is superior to education level to account for Black and White neuropsychological performance discrepancies.
    J Int Neuropsychol Soc Volume: 30 Page(s): 998 - 1002
    12/01/2024 Authors: Goldstein FC; Hanfelt JJ; James TA; Lah JJ; Loring DW
  • Simplifying Complex Figure scoring: Data from the Emory Healthy Brain Study and initial clinical validation.
    J Int Neuropsychol Soc Volume: 30 Page(s): 992 - 997
    12/01/2024 Authors: Loring DW; Simama N; Sanders K; Saurman JR; Zhao L; Lah JJ; Goldstein FC
  • Large-scale deep proteomic analysis in Alzheimer's disease brain regions across race and ethnicity.
    Alzheimers Dement Volume: 20 Page(s): 8878 - 8897
    12/01/2024 Authors: Seifar F; Fox EJ; Shantaraman A; Liu Y; Dammer EB; Modeste E; Duong DM; Yin L; Trautwig AN; Guo Q
  • Correction: Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease.
    Mol Neurodegener Volume: 19 Page(s): 71
    10/11/2024 Authors: Shantaraman A; Dammer EB; Ugochukwu O; Duong DM; Yin L; Carter EK; Gearing M; Chen-Plotkin A; Lee EB; Trojanowski JQ
  • Heparin-enriched plasma proteome is significantly altered in Alzheimer's disease.
    Mol Neurodegener Volume: 19 Page(s): 67
    10/08/2024 Authors: Guo Q; Ping L; Dammer EB; Duong DM; Yin L; Xu K; Shantaraman A; Fox EJ; Golde TE; Johnson ECB
  • Bridging the gap: Multi-omics profiling of brain tissue in Alzheimer's disease and older controls in multi-ethnic populations.
    Alzheimers Dement Volume: 20 Page(s): 7174 - 7192
    10/01/2024 Authors: Reddy JS; Heath L; Linden AV; Allen M; Lopes KDP; Seifar F; Wang E; Ma Y; Poehlman WL; Quicksall ZS
  • An interim exploratory proteomics biomarker analysis of a phase 2 clinical trial to assess the impact of CT1812 in Alzheimer's disease.
    Neurobiol Dis Volume: 199 Page(s): 106575
    09/01/2024 Authors: Lizama BN; North HA; Pandey K; Williams C; Duong D; Cho E; Di Caro V; Ping L; Blennow K; Zetterberg H
  • Lower Prevalence of Asymptomatic Alzheimer's Disease Among Healthy African Americans.
    Ann Neurol Volume: 96 Page(s): 463 - 475
    09/01/2024 Authors: Lah JJ; Tian G; Risk BB; Hanfelt JJ; Wang L; Zhao L; Hales CM; Johnson ECB; Elmor MB; Malakauskas SJ
  • Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease.
    Mol Neurodegener Volume: 19 Page(s): 60
    08/06/2024 Authors: Shantaraman A; Dammer EB; Ugochukwu O; Duong DM; Yin L; Carter EK; Gearing M; Chen-Plotkin A; Lee EB; Trojanowski JQ
  • A deep spatio-temporal attention model of dynamic functional network connectivity shows sensitivity to Alzheimer's in asymptomatic individuals.
    Volume: 2024 Page(s): 1 - 4
    07/01/2024 Authors: Wei Y; Abrol A; Lah J; Qiu D; Calhoun VD
  • Proteomic analysis of Alzheimer's disease cerebrospinal fluid reveals alterations associated with APOE 4 and atomoxetine treatment.
    Sci Transl Med Volume: 16 Page(s): eadn3504
    06/26/2024 Authors: Dammer EB; Shantaraman A; Ping L; Duong DM; Gerasimov ES; Ravindran SP; Gudmundsdottir V; Frick EA; Gomez GT; Walker KA
  • s-SuStaIn: Scaling subtype and stage inference via simultaneous clustering of subjects and biomarkers.
    Volume: 248 Page(s): 461 - 476
    06/01/2024 Authors: Tandon R; Lah JJ; Mitchell CS
  • Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid.
    Alzheimers Dement Volume: 20 Page(s): 4043 - 4065
    06/01/2024 Authors: Wojtas AM; Dammer EB; Guo Q; Ping L; Shantaraman A; Duong DM; Yin L; Fox EJ; Seifar F; Lee EB
  • Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial.
    JAMA Neurol Volume: 81 Page(s): 582 - 593
    06/01/2024 Authors: Wagemann O; Liu H; Wang G; Shi X; Bittner T; Scelsi MA; Farlow MR; Clifford DB; Supnet-Bell C; Santacruz AM
  • Contribution of Peripheral Microvascular Dysfunction to Mild Cognitive Impairment.
    Am J Cardiol Volume: 218 Page(s): 4 - 6
    05/01/2024 Authors: Gold ME; Rogers SC; Kulshreshtha A; Chen Y; Ko Y-A; Cheng ML; Gold DA; Vatsa N; Jain V; Desai S
  • Joint effects of air pollution and neighborhood socioeconomic status on cognitive decline - Mediation by depression, high cholesterol levels, and high blood pressure.
    Sci Total Environ Volume: 923 Page(s): 171535
    05/01/2024 Authors: Mei Y; Christensen GM; Li Z; Waller LA; Ebelt S; Marcus M; Lah JJ; Wingo AP; Wingo TS; Hls A
  • The association between neighborhood deprivation and DNA methylation in an autopsy cohort.
    Aging (Albany NY) Volume: 16 Page(s): 6694 - 6716
    04/24/2024 Authors: Pett L; Li Z; Abrishamcar S; Hodge K; Everson T; Christensen G; Gearing M; Kobor MS; Konwar C; MacIsaac JL
  • APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer's disease pathology.
    Neuron Volume: 112 Page(s): 1110 - 1116.e5
    04/03/2024 Authors: Chemparathy A; Le Guen Y; Chen S; Lee E-G; Leong L; Gorzynski JE; Jensen TD; Ferrasse A; Xu G; Xiang H
  • Disentangling Visual Exploration Differences in Cognitive Impairment.
    IEEE Trans Biomed Eng Volume: 71 Page(s): 1197 - 1208
    04/01/2024 Authors: Jiang Z; Seyedi S; Vickers KL; Manzanares CM; Lah JJ; Levey AI; Clifford GD
  • Association between Fine Particulate Matter Exposure and Cerebrospinal Fluid Biomarkers of Alzheimer's Disease among a Cognitively Healthy Population-Based Cohort.
    Environ Health Perspect Volume: 132 Page(s): 47001
    04/01/2024 Authors: Casey E; Li Z; Liang D; Ebelt S; Levey AI; Lah JJ; Wingo TS; Hls A
  • Examining amyloid reduction as a surrogate endpoint through latent class analysis using clinical trial data for dominantly inherited Alzheimer's disease.
    Alzheimers Dement Volume: 20 Page(s): 2698 - 2706
    04/01/2024 Authors: Wang G; Li Y; Xiong C; Benzinger TLS; Gordon BA; Hassenstab J; Aschenbrenner AJ; McDade E; Clifford DB; Libre-Guerra JJ
  • Differential DNA methylation in the brain as potential mediator of the association between traffic-related PM2.5 and neuropathology markers of Alzheimer's disease.
    Alzheimers Dement Volume: 20 Page(s): 2538 - 2551
    04/01/2024 Authors: Li Z; Liang D; Ebelt S; Gearing M; Kobor MS; Konwar C; Maclsaac JL; Dever K; Wingo AP; Levey AI
  • Association of PM2.5 Exposure and Alzheimer Disease Pathology in Brain Bank Donors-Effect Modification by APOE Genotype.
    Neurology Volume: 102 Page(s): e209162
    03/12/2024 Authors: Christensen GM; Li Z; Liang D; Ebelt S; Gearing M; Levey AI; Lah JJ; Wingo A; Wingo T; Hls A
  • Relationships of Cognitive Measures with Cerebrospinal Fluid but Not Imaging Biomarkers of Alzheimer Disease Vary between Black and White Individuals.
    Ann Neurol Volume: 95 Page(s): 495 - 506
    03/01/2024 Authors: Bonomi S; Lu R; Schindler SE; Bui Q; Lah JJ; Wolk D; Gleason CE; Sperling R; Roberson ED; Levey AI
  • Direct to Consumer Biomarker Testing for Alzheimer Disease-Are We Ready for the Insurance Consequences?
    JAMA Neurol Volume: 81 Page(s): 107 - 108
    02/01/2024 Authors: Arias JJ; Manchester M; Lah J
  • Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease.

    01/24/2024 Authors: Shantaraman A; Dammer EB; Ugochukwu O; Duong DM; Yin L; Carter EK; Gearing M; Chen-Plotkin A; Lee EB; Trojanowski JQ
  • Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid.

    01/11/2024 Authors: Wojtas AM; Dammer EB; Guo Q; Ping L; Shantaraman A; Duong DM; Yin L; Fox EJ; Seifar F; Lee EB
  • Alzheimer's disease cerebrospinal fluid biomarkers and kidney function in normal and cognitively impaired older adults.
    Alzheimers Dement (Amst) Volume: 16 Page(s): e12581
    01/01/2024 Authors: Hajjar I; Neal R; Yang Z; Lah JJ
  • Mixture of regressions with multivariate responses for discovering subtypes in Alzheimer's biomarkers with detection limits.
    Data Sci Sci Volume: 3
    01/01/2024 Authors: Tian G; Hanfelt J; Lah J; Risk BB
  • Comparison of Quantitative Hippocampal Volumes and Structured Scoring Scales in Predicting Alzheimer Disease Diagnosis.
    AJNR Am J Neuroradiol Volume: 44 Page(s): 1411 - 1417
    12/11/2023 Authors: Essien M; Lah J; Weinberg BD; Allen JW; Hu R
  • Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data.
    EBioMedicine Volume: 97 Page(s): 104820
    11/01/2023 Authors: Jo T; Kim J; Bice P; Huynh K; Wang T; Arnold M; Meikle PJ; Giles C; Kaddurah-Daouk R; Saykin AJ
  • Proteomic Network Analysis of Alzheimer's Disease Cerebrospinal Fluid Reveals Alterations Associated with APOE 4 Genotype and Atomoxetine Treatment.
    medRxiv
    10/30/2023 Authors: Dammer EB; Shantaraman A; Ping L; Duong DM; Gerasimov ES; Ravindran SP; Gudmundsdottir V; Frick EA; Gomez GT; Walker KA
  • Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment.
    Neurobiol Dis Volume: 186 Page(s): 106286
    10/01/2023 Authors: Higginbotham L; Carter EK; Dammer EB; Haque RU; Johnson ECB; Duong DM; Yin L; De Jager PL; Bennett DA; Felsky D
  • Robust quantitative susceptibility mapping via approximate message passing with parameter estimation.
    Magn Reson Med Volume: 90 Page(s): 1414 - 1430
    10/01/2023 Authors: Huang S; Lah JJ; Allen JW; Qiu D
  • A protein panel in cerebrospinal fluid for diagnostic and predictive assessment of Alzheimer's disease.
    Sci Transl Med Volume: 15 Page(s): eadg4122
    09/06/2023 Authors: Haque R; Watson CM; Liu J; Carter EK; Duong DM; Lah JJ; Wingo AP; Roberts BR; Johnson ECB; Saykin AJ
  • Integration of plasma and CSF metabolomics with CSF proteomic reveals novel associations between lipid mediators and central nervous system vascular and energy metabolism.
    Sci Rep Volume: 13 Page(s): 13752
    08/23/2023 Authors: Borkowski K; Seyfried NT; Arnold M; Lah JJ; Levey AI; Hales CM; Dammer EB; Blach C; Louie G; Kaddurah-Daouk R
  • Author Correction: Predicting Alzheimer's disease progression using multi-modal deep learning approach.
    Sci Rep Volume: 13 Page(s): 12466
    08/01/2023 Authors: Lee G; Nho K; Kang B; Sohn K-A; Kim D; Alzheimers Disease Neuroimaging Initiative
  • Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease.
    Nat Med Volume: 29 Page(s): 1979 - 1988
    08/01/2023 Authors: Johnson ECB; Bian S; Haque RU; Carter EK; Watson CM; Gordon BA; Ping L; Duong DM; Epstein MP; McDade E
  • Prognostic relevance of gait-related cognitive functions for dementia conversion in amnestic mild cognitive impairment.
    BMC Geriatr Volume: 23 Page(s): 462
    07/31/2023 Authors: Tuena C; Maestri S; Serino S; Pedroli E; Stramba-Badiale M; Riva G; Alzheimers Disease Neuroimaging Initiative
  • APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer's Disease pathology.
    medRxiv
    07/24/2023 Authors: Chemparathy A; Guen YL; Chen S; Lee E-G; Leong L; Gorzynski J; Xu G; Belloy M; Kasireddy N; Tauber AP
  • Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer's disease.
    Mol Neurodegener Volume: 18 Page(s): 48
    07/19/2023 Authors: Modeste ES; Ping L; Watson CM; Duong DM; Dammer EB; Johnson ECB; Roberts BR; Lah JJ; Levey AI; Seyfried NT
  • Differential DNA Methylation in the Brain as Potential Mediator of the Association between Traffic-related PM2.5 and Neuropathology Markers of Alzheimer's Disease.
    medRxiv
    06/30/2023 Authors: Li Z; Liang D; Ebelt S; Gearing M; Kobor MS; Konwar C; Maclsaac JL; Dever K; Wingo A; Levey A
  • Associations between neuropsychiatric symptoms of affective and vegetative domains and brain morphology in aging people with mild cognitive impairment and Alzheimer's disease.
    Int J Geriatr Psychiatry Volume: 38 Page(s): e5952
    06/01/2023 Authors: Cannizzaro A; Ronat L; El Haffaf LM; Hanganu A; ADNI
  • Telehealth equivalence of the Montreal cognitive assessment (MoCA): Results from the Emory healthy brain study (EHBS).
    J Am Geriatr Soc Volume: 71 Page(s): 1931 - 1936
    06/01/2023 Authors: Loring DW; Lah JJ; Goldstein FC
  • Magnetic resonance evidence of increased iron content in subcortical brain regions in asymptomatic Alzheimer's disease.
    Hum Brain Mapp Volume: 44 Page(s): 3072 - 3083
    06/01/2023 Authors: Lin Q; Shahid S; Hone-Blanchet A; Huang S; Wu J; Bisht A; Loring D; Goldstein F; Levey A; Crosson B
  • Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease.
    Sci Data Volume: 10 Page(s): 261
    05/09/2023 Authors: Watson CM; Dammer EB; Ping L; Duong DM; Modeste E; Carter EK; Johnson ECB; Levey AI; Lah JJ; Roberts BR
  • The Rey Auditory Verbal Learning Test: Cross-validation of Mayo Normative Studies (MNS) demographically corrected norms with confidence interval estimates.
    J Int Neuropsychol Soc Volume: 29 Page(s): 397 - 405
    05/01/2023 Authors: Loring DW; Saurman JL; John SE; Bowden SC; Lah JJ; Goldstein FC
  • Fine particulate air pollution and neuropathology markers of Alzheimer's disease in donors with and without APOE 4 alleles - results from an autopsy cohort.
    medRxiv
    04/07/2023 Authors: Christensen GM; Li Z; Liang D; Ebelt S; Gearing M; Levey AI; Lah JJ; Wingo AP; Wingo TS; Huels A
  • Alzheimer's disease genetic burden is associated with mid-life depression among persons with normal cognition.
    Alzheimers Dement Volume: 19 Page(s): 868 - 874
    03/01/2023 Authors: Wingo TS; Gerasimov ES; Canon SM; Lah JJ; Levey AI; Wingo AP
  • Predictors of Cognitive Decline in Healthy Middle-Aged Individuals with Asymptomatic Alzheimer's Disease.
    Res Sq
    02/28/2023 Authors: Tandon R; Zhao L; Watson CM; Elmor M; Heilman C; Sanders K; Hales CM; Yang H; Loring DW; Goldstein FC
  • Blood-based biomarkers in Alzheimer's disease: Future directions for implementation.
    Alzheimers Dement (Amst) Volume: 15 Page(s): e12508
    01/01/2023 Authors: Suridjan I; van der Flier WM; Monsch AU; Burnie N; Baldor R; Sabbagh M; Vilaseca J; Cai D; Carboni M; Lah JJ
  • Machine Learning Selection of Most Predictive Brain Proteins Suggests Role of Sugar Metabolism in Alzheimer's Disease.
    J Alzheimers Dis Volume: 92 Page(s): 411 - 424
    01/01/2023 Authors: Tandon R; Levey AI; Lah JJ; Seyfried NT; Mitchell CS
  • Multi-platform proteomic analysis of Alzheimer's disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome.
    Alzheimers Res Ther Volume: 14 Page(s): 174
    11/17/2022 Authors: Dammer EB; Ping L; Duong DM; Modeste ES; Seyfried NT; Lah JJ; Levey AI; Johnson ECB
  • CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels.
    Nat Aging Volume: 2 Page(s): 1040 - 1053
    11/01/2022 Authors: Del Campo M; Peeters CFW; Johnson ECB; Vermunt L; Hok-A-Hin YS; van Nee M; Chen-Plotkin A; Irwin DJ; Hu WT; Lah JJ
  • Examination of the reliability and feasibility of two smartphone applications to assess executive functioning in racially diverse older adults.
    Neuropsychol Dev Cogn B Aging Neuropsychol Cogn Volume: 29 Page(s): 1068 - 1086
    11/01/2022 Authors: John SE; Evans SA; Kim B; Ozgul P; Loring DW; Parker M; Lah JJ; Levey AI; Goldstein FC
  • Multimodal Machine Learning to Identify Risk of Progression in Asymptomatic Alzheimer's Disease
    Volume: 92 Page(s): S56 - S56
    10/01/2022 Authors: Tandon R; Watson CM; Seyfried NT; Lah JJ; Mitchell CS
  • Network Proteomic Analysis Identifies Diverse Pathophysiological Signatures in the Lewy Body Dementia Brain
    Volume: 92 Page(s): S61 - S61
    10/01/2022 Authors: Higginbotham L; Dammer EB; Shantaraman A; Duong DM; Yin L; Chen-Plotkin A; Lee EB; Lah JJ; Levey AI; Seyfried NT
  • Race-Dependent Differences in Biomarkers Lead to Lower Rates of Alzheimer's Disease Classification in Symptomatic and Asymptomatic African Americans
    Volume: 92 Page(s): S58 - S59
    10/01/2022 Authors: Lah JJ; Parker MW; Tian G; Hales CM; Johnson ECB; Hanfelt JJ; Risk BB; Levey AI; Hajjar IM
  • A probabilistic Bayesian approach to recover R2*$$ {R}_{2\ast } $$ map and phase images for quantitative susceptibility mapping.
    Magn Reson Med Volume: 88 Page(s): 1624 - 1642
    10/01/2022 Authors: Huang S; Lah JJ; Allen JW; Qiu D
  • The trend of disruption in the functional brain network topology of Alzheimer's disease.
    Sci Rep Volume: 12 Page(s): 14998
    09/02/2022 Authors: Fathian A; Jamali Y; Raoufy MR; Alzheimers Disease Neuroimaging Initiative
  • The complex relationship of air pollution and neighborhood socioeconomic status and their association with cognitive decline.
    Environ Int Volume: 167 Page(s): 107416
    09/01/2022 Authors: Christensen GM; Li Z; Pearce J; Marcus M; Lah JJ; Waller LA; Ebelt S; Hls A
  • Neighborhood characteristics as confounders and effect modifiers for the association between air pollution exposure and subjective cognitive functioning.
    Environ Res Volume: 212 Page(s): 113221
    09/01/2022 Authors: Li Z; Christensen GM; Lah JJ; Marcus M; Russell AG; Ebelt S; Waller LA; Hls A
  • Glucose metabolism patterns: A potential index to characterize brain ageing and predict high conversion risk into cognitive impairment.
    Geroscience Volume: 44 Page(s): 2319 - 2336
    08/01/2022 Authors: Jiang J; Sheng C; Chen G; Liu C; Jin S; Li L; Jiang X; Han Y; Alzheimers Disease Neuroimaging Initiative
  • Author Correction: FAM222A encodes a protein which accumulates in plaques in Alzheimer's disease.
    Nat Commun Volume: 13 Page(s): 4006
    07/11/2022 Authors: Yan T; Liang J; Gao J; Wang L; Fujioka H; Alzheimer Disease Neuroimaging Initiative; Zhu X; Wang X
  • Genetic Evidence Supporting a Causal Role of Depression in Alzheimer's Disease.
    Biol Psychiatry Volume: 92 Page(s): 25 - 33
    07/01/2022 Authors: Harerimana NV; Liu Y; Gerasimov ES; Duong D; Beach TG; Reiman EM; Schneider JA; Boyle P; Lori A; Bennett DA
  • A phase II study repurposing atomoxetine for neuroprotection in mild cognitive impairment.
    Brain Volume: 145 Page(s): 1924 - 1938
    06/30/2022 Authors: Levey AI; Qiu D; Zhao L; Hu WT; Duong DM; Higginbotham L; Dammer EB; Seyfried NT; Wingo TS; Hales CM
  • Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.
    Sci Rep Volume: 12 Page(s): 6117
    04/12/2022 Authors: Heath L; Earls JC; Magis AT; Kornilov SA; Lovejoy JC; Funk CC; Rappaport N; Logsdon BA; Mangravite LM; Kunkle BW
  • New insights into the genetic etiology of Alzheimer's disease and related dementias.
    Nat Genet Volume: 54 Page(s): 412 - 436
    04/01/2022 Authors: Bellenguez C; Kkali F; Jansen IE; Kleineidam L; Moreno-Grau S; Amin N; Naj AC; Campos-Martin R; Grenier-Boley B; Andrade V
  • The Georgia Memory Net: Implementation of a statewide program to diagnose and treat Alzheimer's disease and related dementias.
    J Am Geriatr Soc Volume: 70 Page(s): 1257 - 1267
    04/01/2022 Authors: Bender AA; McIntosh RL; Sudduth S; Harris M; Tuckey K; Morgan JC; Jungerman JM; Cox A; Moore MA; Ingram B
  • Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer's disease.
    Nat Commun Volume: 13 Page(s): 1495
    03/21/2022 Authors: Duong MT; Das SR; Lyu X; Xie L; Richardson H; Xie SX; Yushkevich PA; Alzheimers Disease Neuroimaging Initiative (ADNI); Wolk DA; Nasrallah IM
  • Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level.
    Nat Neurosci Volume: 25 Page(s): 213 - 225
    02/01/2022 Authors: Johnson ECB; Carter EK; Dammer EB; Duong DM; Gerasimov ES; Liu Y; Liu J; Betarbet R; Ping L; Yin L
  • Brain microRNAs are associated with variation in cognitive trajectory in advanced age.
    Transl Psychiatry Volume: 12 Page(s): 47
    02/01/2022 Authors: Wingo AP; Wang M; Liu J; Breen MS; Yang H-S; Tang B; Schneider JA; Seyfried NT; Lah JJ; Levey AI
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    Neurosci Lett Volume: 694 Page(s): 41 - 45
    02/16/2019 Authors: Ye X; Zhou W; Zhang J; for Alzheimers Disease Neuroimaging Initiative
  • Predicting Alzheimer's disease progression using multi-modal deep learning approach.
    Sci Rep Volume: 9 Page(s): 1952
    02/13/2019 Authors: Lee G; Nho K; Kang B; Sohn K-A; Kim D; for Alzheimers Disease Neuroimaging Initiative
  • Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs.
    Neurobiol Aging Volume: 74 Page(s): 135 - 146
    02/01/2019 Authors: Katsumata Y; Nelson PT; Estus S; Alzheimer's Disease Neuroimaging Initiative (ADNI); Fardo DW
  • Amyloid beta-positive subjects exhibit longitudinal network-specific reductions in spontaneous brain activity.
    Neurobiol Aging Volume: 74 Page(s): 191 - 201
    02/01/2019 Authors: Avants BB; Hutchison RM; Mikulskis A; Salinas-Valenzuela C; Hargreaves R; Beaver J; Chiao P; Alzheimer's Disease Neuroimaging Initiative
  • Functional signature of conversion of patients with mild cognitive impairment.
    Neurobiol Aging Volume: 74 Page(s): 21 - 37
    02/01/2019 Authors: Delli Pizzi S; Punzi M; Sensi SL; Alzheimer's Disease Neuroimaging Initiative
  • QuickNAT: A fully convolutional network for quick and accurate segmentation of neuroanatomy.
    Neuroimage Volume: 186 Page(s): 713 - 727
    02/01/2019 Authors: Guha Roy A; Conjeti S; Navab N; Wachinger C; Alzheimer's Disease Neuroimaging Initiative
  • Disease progression timeline estimation for Alzheimer's disease using discriminative event based modeling.
    Neuroimage Volume: 186 Page(s): 518 - 532
    02/01/2019 Authors: Venkatraghavan V; Bron EE; Niessen WJ; Klein S; Alzheimer's Disease Neuroimaging Initiative
  • Accuracy and generalization capability of an automatic method for the detection of typical brain hypometabolism in prodromal Alzheimer disease.
    Eur J Nucl Med Mol Imaging Volume: 46 Page(s): 334 - 347
    02/01/2019 Authors: De Carli F; Nobili F; Pagani M; Bauckneht M; Massa F; Grazzini M; Jonsson C; Peira E; Morbelli S; Arnaldi D
  • Accurate risk estimation of -amyloid positivity to identify prodromal Alzheimer's disease: Cross-validation study of practical algorithms.
    Alzheimers Dement Volume: 15 Page(s): 194 - 204
    02/01/2019 Authors: Palmqvist S; Insel PS; Zetterberg H; Blennow K; Brix B; Stomrud E; Alzheimer's Disease Neuroimaging Initiative; Swedish BioFINDER study; Mattsson N; Hansson O
  • Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers.
    Alzheimers Dement Volume: 15 Page(s): 232 - 244
    02/01/2019 Authors: Nho K; Kueider-Paisley A; MahmoudianDehkordi S; Arnold M; Risacher SL; Louie G; Blach C; Baillie R; Han X; Kastenmller G
  • A Novel Method to Estimate Long-Term Chronological Changes From Fragmented Observations in Disease Progression.
    Clin Pharmacol Ther Volume: 105 Page(s): 436 - 447
    02/01/2019 Authors: Ishida T; Tokuda K; Hisaka A; Honma M; Kijima S; Takatoku H; Iwatsubo T; Moritoyo T; Suzuki H; Alzheimer's Disease Neuroimaging Initiative
  • MAPT rs242557 variant is associated with hippocampus tau uptake on 18F-AV-1451 PET in non-demented elders.
    Aging (Albany NY) Volume: 11 Page(s): 874 - 884
    01/31/2019 Authors: Shen X-N; Miao D; Li J-Q; Tan C-C; Cao X-P; Tan L; Yu J-T
  • Longitudinal Brain Atrophy Rates in Transient Ischemic Attack and Minor Ischemic Stroke Patients and Cognitive Profiles.
    Front Neurol Volume: 10 Page(s): 18
    01/01/2019 Authors: Munir M; Ursenbach J; Reid M; Gupta Sah R; Wang M; Sitaram A; Aftab A; Tariq S; Zamboni G; Griffanti L
  • Diffusion MRI Indices and Their Relation to Cognitive Impairment in Brain Aging: The Updated Multi-protocol Approach in ADNI3.
    Front Neuroinform Volume: 13 Page(s): 2
    01/01/2019 Authors: Zavaliangos-Petropulu A; Nir TM; Thomopoulos SI; Reid RI; Bernstein MA; Borowski B; Jack CR; Weiner MW; Jahanshad N; Thompson PM
  • A Homolog for Dementia Case Finding with Replication in the Alzheimer's Disease Neuroimaging Initiative.
    J Alzheimers Dis Volume: 67 Page(s): 67 - 79
    01/01/2019 Authors: Royall DR; Palmer RF; Alzheimers Disease Neuroimaging Initiative
  • Next Generation Sequencing Analysis in Early Onset Dementia Patients.
    J Alzheimers Dis Volume: 67 Page(s): 243 - 256
    01/01/2019 Authors: Bonvicini C; Scassellati C; Benussi L; Di Maria E; Maj C; Ciani M; Fostinelli S; Mega A; Bocchetta M; Lanzi G
  • Random forest prediction of Alzheimer's disease using pairwise selection from time series data.
    PLoS One Volume: 14 Page(s): e0211558
    01/01/2019 Authors: Moore PJ; Lyons TJ; Gallacher J; Alzheimers Disease Neuroimaging Initiative
  • The Relationship Between Hippocampal Volumes and Delayed Recall Is Modified by APOE 4 in Mild Cognitive Impairment.
    Front Aging Neurosci Volume: 11 Page(s): 36
    01/01/2019 Authors: Wang X; Zhou W; Ye T; Lin X; Zhang J; Alzheimers Disease Neuroimaging Initiative
  • Longitudinal Functional Brain Mapping in Supernormals.
    Cereb Cortex Volume: 29 Page(s): 242 - 252
    01/01/2019 Authors: Wang X; Ren P; Baran TM; Raizada RDS; Mapstone M; Lin F; Alzheimers Disease Neuroimaging Initiative
  • Robust Motion Regression of Resting-State Data Using a Convolutional Neural Network Model.
    Front Neurosci Volume: 13 Page(s): 169
    01/01/2019 Authors: Yang Z; Zhuang X; Sreenivasan K; Mishra V; Cordes D; Alzheimers Disease Neuroimaging Initiative
  • Evaluating trajectories of episodic memory in normal cognition and mild cognitive impairment: Results from ADNI.
    PLoS One Volume: 14 Page(s): e0212435
    01/01/2019 Authors: Ding X; Charnigo RJ; Schmitt FA; Kryscio RJ; Abner EL; Alzheimers Disease Neuroimaging Initiative
  • Prognosis of conversion of mild cognitive impairment to Alzheimer's dementia by voxel-wise Cox regression based on FDG PET data.
    Neuroimage Clin Volume: 21 Page(s): 101637
    01/01/2019 Authors: Srensen A; Blazhenets G; Rcker G; Schiller F; Meyer PT; Frings L; Alzheimer's Disease Neuroimaging Initiative
  • Cortical thickness atrophy in the transentorhinal cortex in mild cognitive impairment.
    Neuroimage Clin Volume: 21 Page(s): 101617
    01/01/2019 Authors: Kulason S; Tward DJ; Brown T; Sicat CS; Liu C-F; Ratnanather JT; Younes L; Bakker A; Gallagher M; Albert M
  • Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative.
    Alzheimers Dement Volume: 15 Page(s): 106 - 152
    01/01/2019 Authors: Veitch DP; Weiner MW; Aisen PS; Beckett LA; Cairns NJ; Green RC; Harvey D; Jack CR; Jagust W; Morris JC
  • Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome.
    Alzheimers Dement Volume: 15 Page(s): 76 - 92
    01/01/2019 Authors: MahmoudianDehkordi S; Arnold M; Nho K; Ahmad S; Jia W; Xie G; Louie G; Kueider-Paisley A; Moseley MA; Thompson JW
  • The Feasibility of Measuring Gait in an Outpatient Cognitive Neurology Clinical Setting.
    J Alzheimers Dis Volume: 71 Page(s): S51 - S55
    01/01/2019 Authors: Nocera JR; Arsik I; Keskinocak P; Lepley-Flood A; Lah JJ; Levey AI; Esper GJ
  • Rationale and Design of the Emory Healthy Aging and Emory Healthy Brain Studies.
    Neuroepidemiology Volume: 53 Page(s): 187 - 200
    01/01/2019 Authors: Goetz ME; Hanfelt JJ; John SE; Bergquist SH; Loring DW; Quyyumi A; Clifford GD; Vaccarino V; Goldstein F; Johnson Nd TM
  • Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.
    Nat Med Volume: 25 Page(s): 152 - 164
    01/01/2019 Authors: Swarup V; Hinz FI; Rexach JE; Noguchi K-I; Toyoshiba H; Oda A; Hirai K; Sarkar A; Seyfried NT; Cheng C
  • Sex-specific genetic predictors of Alzheimer's disease biomarkers.
    Acta Neuropathol Volume: 136 Page(s): 857 - 872
    12/01/2018 Authors: Deming Y; Dumitrescu L; Barnes LL; Thambisetty M; Kunkle B; Gifford KA; Bush WS; Chibnik LB; Mukherjee S; De Jager PL
  • Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference.
    Nat Commun Volume: 9 Page(s): 4273
    10/15/2018 Authors: Young AL; Marinescu RV; Oxtoby NP; Bocchetta M; Yong K; Firth NC; Cash DM; Thomas DL; Dick KM; Cardoso J
  • Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease.
    Mol Neurodegener Volume: 13 Page(s): 52
    10/04/2018 Authors: Johnson ECB; Dammer EB; Duong DM; Yin L; Thambisetty M; Troncoso JC; Lah JJ; Levey AI; Seyfried NT
  • Quantitative Proteomics of CSF and Plasma Reveals Candidate Biomarkers Linked to Immune-Related Pathways in Alzheimer's Disease
    Volume: 84 Page(s): S64 - S65
    10/01/2018 Authors: Duong DM; Lah JJ; Levey AI; Seyfried NT
  • Proteomic Changes in Frontotemporal Lobar Degeneration Due to Microtubule Associated Protein Tau (MAPT) Mutations
    Volume: 84 Page(s): S161 - S161
    10/01/2018 Authors: Hales C; Duc D; Seyfried N; Webster J; Levey A; Lah J; Dammer E
  • Improving Alzheimer's Disease Care for the Citizens of Georgia: The Georgia Memory Network
    Volume: 84 Page(s): S69 - S69
    10/01/2018 Authors: Hales C; Dillard R; Sudduth S; Medders L; Loring D; Hepburn K; Johnson T; Humberstone S; Levey A; Lah J
  • Quantitative Proteomics of the Human Brain Reveals Proteins Associated with Cognitive Resilience
    ANNALS OF NEUROLOGY Volume: 84 Page(s): S62 - S62
    10/01/2018 Authors: Wingo AP; Dammer EB; Duc D; Breen M; Logsdon B; Yang J; Beach TG; Reiman E; Thambisetty M; Troncosco J
  • Brain microRNAs Associated with Cognitive Resilience
    Volume: 84 Page(s): S161 - S162
    10/01/2018 Authors: Wingo AP; Perumal T; Yang H-S; Schneider JA; Jin P; Lah JJ; Levey A; Bennett DA; De Jager PL; Wingo TS
  • A Search for Predictive AD Biomarkers: The Emory Healthy Brain Study
    Volume: 84 Page(s): S170 - S170
    10/01/2018 Authors: Lah JJ; Goetz ME; John S; Lewis LM; Lomba C; Bergquist SH; Clifford GD; Goldstein FC; Loring DW; Kuerston R
  • Comprehensive Mapping of Alzheimer's Disease Brain Ubiquitin Pattern Revealed Novel Tau Ubiquitylation Sites
    Volume: 84 Page(s): S65 - S65
    10/01/2018 Authors: Abreha M; Dammer E; Ping L; Duc D; Gearing M; Lah J; Levey A; Seyfried N
  • Effects of APOE Genotype on Protein Co-Expression in Alzheimer's Disease
    Volume: 84 Page(s): S164 - S164
    10/01/2018 Authors: Dammer EB; Dai J; Johnson ECB; Duong DM; Gearing M; Lah JJ; Levey AI; Wingo TS; Seyfried NT
  • Establishing a Roadmap for Brain-Based Protein Biomarkers in Alzheimer's Disease
    Volume: 84 Page(s): S165 - S166
    10/01/2018 Authors: Zhou M; Duong DM; Ping L; Dammer EB; Gearing M; Lah JJ; Levey AI; Seyfried NT
  • Deep Proteomic Network Analysis of AD Brain Reveals Alterations in RNA Binding Proteins and RNA Splicing Associated with Disease
    Volume: 84 Page(s): S68 - S68
    10/01/2018 Authors: Johnson E; Dammer E; Duc D; Thambisetty M; Troncoso J; Lah J; Levey A; Seyfried N
  • The Role of the Inflammation Module Hub Protein Moesin in AD
    Volume: 84 Page(s): S160 - S160
    10/01/2018 Authors: Betarbet R; Raza SA; Webster J; Eric DB; Duong D; Seyfried NT; Levey AI; Rangaraju S; Lah JJ
  • Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease.
    Proteomics Volume: 18 Page(s): e1800108
    10/01/2018 Authors: Abreha MH; Dammer EB; Ping L; Zhang T; Duong DM; Gearing M; Lah JJ; Levey AI; Seyfried NT
  • Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer's disease.
    Sci Rep Volume: 8 Page(s): 13807
    09/14/2018 Authors: Huang S-Y; Hsu J-L; Lin K-J; Liu H-L; Wey S-P; Hsiao I-T; Alzheimers Disease Neuroimaging Initiative
  • The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.
    Sci Data Volume: 5 Page(s): 180185
    09/11/2018 Authors: Wang M; Beckmann ND; Roussos P; Wang E; Zhou X; Wang Q; Ming C; Neff R; Ma W; Fullard JF
  • Latent classes of mild cognitive impairment are associated with clinical outcomes and neuropathology: Analysis of data from the National Alzheimer's Coordinating Center.
    Neurobiol Dis Volume: 117 Page(s): 62 - 71
    09/01/2018 Authors: Hanfelt JJ; Peng L; Goldstein FC; Lah JJ
  • Medical Image Imputation from Image Collections.
    IEEE Trans Med Imaging
    08/22/2018 Authors: Dalca AV; Bouman KL; Freeman WT; Rost NS; Sabuncu MR; Golland P
  • Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.
    JAMA Neurol Volume: 75 Page(s): 989 - 998
    08/01/2018 Authors: Hohman TJ; Dumitrescu L; Barnes LL; Thambisetty M; Beecham G; Kunkle B; Gifford KA; Bush WS; Chibnik LB; Mukherjee S
  • RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.
    J Biol Chem Volume: 293 Page(s): 11047 - 11066
    07/13/2018 Authors: Bishof I; Dammer EB; Duong DM; Kundinger SR; Gearing M; Lah JJ; Levey AI; Seyfried NT
  • Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins.
    Mol Neurodegener Volume: 13 Page(s): 34
    06/28/2018 Authors: Rangaraju S; Dammer EB; Raza SA; Gao T; Xiao H; Betarbet R; Duong DM; Webster JA; Hales CM; Lah JJ
  • Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease.
    Mol Neurodegener Volume: 13 Page(s): 24
    05/21/2018 Authors: Rangaraju S; Dammer EB; Raza SA; Rathakrishnan P; Xiao H; Gao T; Duong DM; Pennington MW; Lah JJ; Seyfried NT
  • Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer's Disease using structural MR and FDG-PET images.
    Sci Rep Volume: 8 Page(s): 5697
    04/09/2018 Authors: Lu D; Popuri K; Ding GW; Balachandar R; Beg MF; Alzheimers Disease Neuroimaging Initiative
  • 18F-florbetapir Positron Emission Tomography-determined Cerebral -Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery.
    Anesthesiology Volume: 128 Page(s): 728 - 744
    04/01/2018 Authors: Klinger RY; James OG; Borges-Neto S; Bisanar T; Li Y-J; Qi W; Berger M; Terrando N; Newman MF; Doraiswamy PM
  • Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease.
    Sci Data Volume: 5 Page(s): 180036
    03/13/2018 Authors: Ping L; Duong DM; Yin L; Gearing M; Lah JJ; Levey AI; Seyfried NT
  • Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states.
    Sci Rep Volume: 8 Page(s): 4103
    03/07/2018 Authors: Mahjoub I; Mahjoub MA; Rekik I; Alzheimers Disease Neuroimaging Initiative
  • Evidence for brain glucose dysregulation in Alzheimer's disease.
    Alzheimers Dement Volume: 14 Page(s): 318 - 329
    03/01/2018 Authors: An Y; Varma VR; Varma S; Casanova R; Dammer E; Pletnikova O; Chia CW; Egan JM; Ferrucci L; Troncoso J
  • Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases.
    Alzheimers Dement Volume: 14 Page(s): 352 - 366
    03/01/2018 Authors: Allen M; Wang X; Burgess JD; Watzlawik J; Serie DJ; Younkin CS; Nguyen T; Malphrus KG; Lincoln S; Carrasquillo MM
  • The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): study protocol for a randomized controlled trial.
    Trials Volume: 19 Page(s): 46
    01/18/2018 Authors: Scherer RW; Drye L; Mintzer J; Lanctt K; Rosenberg P; Herrmann N; Padala P; Brawman-Mintzer O; Burke W; Craft S
  • Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice.
    J Neurosci Volume: 38 Page(s): 74 - 92
    01/03/2018 Authors: Chalermpalanupap T; Schroeder JP; Rorabaugh JM; Liles LC; Lah JJ; Levey AI; Weinshenker D
  • Differential Phagocytic Properties of CD45low Microglia and CD45high Brain Mononuclear Phagocytes-Activation and Age-Related Effects.
    Front Immunol Volume: 9 Page(s): 405
    01/01/2018 Authors: Rangaraju S; Raza SA; Li NX; Betarbet R; Dammer EB; Duong D; Lah JJ; Seyfried NT; Levey AI
  • Dual-Model Radiomic Biomarkers Predict Development of Mild Cognitive Impairment Progression to Alzheimer's Disease.
    Front Neurosci Volume: 12 Page(s): 1045
    01/01/2018 Authors: Zhou H; Jiang J; Lu J; Wang M; Zhang H; Zuo C; Alzheimers Disease Neuroimaging Initiative
  • Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease.
    Front Mol Neurosci Volume: 11 Page(s): 454
    01/01/2018 Authors: Dai J; Johnson ECB; Dammer EB; Duong DM; Gearing M; Lah JJ; Levey AI; Wingo TS; Seyfried NT
  • A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain.
    EMBO Mol Med Volume: 10 Page(s): 48 - 62
    01/01/2018 Authors: Umoh ME; Dammer EB; Dai J; Duong DM; Lah JJ; Levey AI; Gearing M; Glass JD; Seyfried NT
  • Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy.
    J Neuropathol Exp Neurol Volume: 77 Page(s): 40 - 49
    01/01/2018 Authors: Cherry JD; Zeineddin A; Dammer EB; Webster JA; Duong D; Seyfried NT; Levey AI; Alvarez VE; Huber BR; Stein TD
  • Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease.
    Alzheimers Dement (Amst) Volume: 10 Page(s): 595 - 598
    01/01/2018 Authors: Peloso GM; van der Lee SJ; International Genomics of Alzheimer's Project (IGAP); Destefano AL; Seshardi S
  • Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease.
    Mol Neurodegener Volume: 12 Page(s): 82
    11/06/2017 Authors: McKenzie AT; Moyon S; Wang M; Katsyv I; Song W-M; Zhou X; Dammer EB; Duong DM; Aaker J; Zhao Y
  • Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty.
    Sci Rep Volume: 7 Page(s): 14052
    10/25/2017 Authors: Du L; Liu K; Yao X; Yan J; Risacher SL; Han J; Guo L; Saykin AJ; Shen L; Alzheimers Disease Neuroimaging Initiative
  • Systems Pharmacology Approach to Identify Novel Kv1.3 Channel Dependent Mechanisms in Microglial Activation
    Volume: 82 Page(s): S30 - S30
    10/01/2017 Authors: Raza SA; Deng Q; Dammer EB; Duong D; Tansey MG; Lah JJ; Betarbet R; Seyfried NT; Levey AI; Rangaraju S
  • Early-Onset Alzheimer's Disease Is Associated with APOB and Higher Plasma Cholesterol Independent of APOE
    Volume: 82 Page(s): S53 - S53
    10/01/2017 Authors: Wingo TS; Cutler DJ; Wingo AP; Le N-A; Rabinovici GD; Miller BL; Lah JJ; Levey AI
  • Targeting Microglial and Macrophage Kv1.3 Potassium Channels as a Therapeutic Strategy in Alzheimer's Disease
    Volume: 82 Page(s): S50 - S51
    10/01/2017 Authors: Rangaraju S; Raza SA; Lah JJ; Tansey M; Levey AI
  • Targeting Microglial and Macrophage Kv1.3 Potassium Channels as a Therapeutic Strategy in Alzheimer's Disease
    Volume: 82 Page(s): S212 - S213
    10/01/2017 Authors: Rangaraju S; Raza SA; Tansey MG; Lah JJ; Levey AI
  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
    Nat Genet Volume: 49 Page(s): 1373 - 1384
    09/01/2017 Authors: Sims R; van der Lee SJ; Naj AC; Bellenguez C; Badarinarayan N; Jakobsdottir J; Kunkle BW; Boland A; Raybould R; Bis JC
  • Integrating Next-Generation Genomic Sequencing and Mass Spectrometry To Estimate Allele-Specific Protein Abundance in Human Brain.
    J Proteome Res Volume: 16 Page(s): 3336 - 3347
    09/01/2017 Authors: Wingo TS; Duong DM; Zhou M; Dammer EB; Wu H; Cutler DJ; Lah JJ; Levey AI; Seyfried NT
  • Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features.
    Sci Rep Volume: 7 Page(s): 8137
    08/15/2017 Authors: Singanamalli A; Wang H; Madabhushi A; Alzheimers Disease Neuroimaging Initiative
  • Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
    Alzheimers Dement Volume: 13 Page(s): 727 - 738
    07/01/2017 Authors: Jun GR; Chung J; Mez J; Barber R; Beecham GW; Bennett DA; Buxbaum JD; Byrd GS; Carrasquillo MM; Crane PK
  • A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation.
    J Neuroinflammation Volume: 14 Page(s): 128
    06/26/2017 Authors: Rangaraju S; Raza SA; Pennati A; Deng Q; Dammer EB; Duong D; Pennington MW; Tansey MG; Lah JJ; Betarbet R
  • Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease.
    JAMA Neurol Volume: 74 Page(s): 557 - 566
    05/01/2017 Authors: Mattsson N; Andreasson U; Zetterberg H; Blennow K; Alzheimers Disease Neuroimaging Initiative
  • Comparison of detergent-insoluble proteome changes in autosomal dominant Alzheimer's disease brain to late onset AD and transgenic rodents
    Volume: 88
    04/18/2017 Authors: Hales C; Dammer E; Duong D; Gearing M; Cohen R; Wingo T; Lah J; Levey A; Seyfried N
  • Association of AHA Cardiovascular Health Metrics With Cognitive Function, Depression, and Anxiety: The Emory Healthy Aging Study
    Volume: 135
    03/07/2017 Authors: Alonso A; Goldstein FC; Vaccarino V; Levey AI; Lah JJ; Marcus M
  • Family History of Cardiovascular Disease is Associated With Cognitive Function: The Emory Healthy Aging Study
    Volume: 135
    03/07/2017 Authors: Goetz ME; Marcus M; Vaccarino V; Goldstein F; Levey A; Lah J
  • A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease.
    Cell Syst Volume: 4 Page(s): 60 - 72.e4
    01/25/2017 Authors: Seyfried NT; Dammer EB; Swarup V; Nandakumar D; Duong DM; Yin L; Deng Q; Nguyen T; Hales CM; Wingo T
  • Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease.
    Sci Rep Volume: 7 Page(s): 39880
    01/12/2017 Authors: Huang M; Yang W; Feng Q; Chen W; Alzheimers Disease Neuroimaging Initiative
  • Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway.
    Mol Psychiatry Volume: 22 Page(s): 13 - 23
    01/01/2017 Authors: Varma VR; Varma S; An Y; Hohman TJ; Seddighi S; Casanova R; Beri A; Dammer EB; Seyfried NT; Pletnikova O
  • Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression.
    Proteomics Volume: 16 Page(s): 3042 - 3053
    12/01/2016 Authors: Hales CM; Dammer EB; Deng Q; Duong DM; Gearing M; Troncoso JC; Thambisetty M; Lah JJ; Shulman JM; Levey AI
  • A Genetic Study of a Large Pedigree with Late-Onset Alzheimer's Disease
    Volume: 80 Page(s): S159 - S159
    10/01/2016 Authors: Wingo TS; Cutler DJ; Lah JJ; Levey AI
  • NADPH Dehydrogenase Quinone 1 (NQO1) Demonstrates Increased Expression and Pathologic Aggregation in Glial Cells in Chronic Traumatic Encephalopathy
    Volume: 80 Page(s): S195 - S195
    10/01/2016 Authors: Hales C; Zeineddin A; Webster J; Giuliano J; Duong D; Seyfried N; Dammer E; Mckee A; Levey A; Lah J
  • Presenilin 1 transgene addition to amyloid precursor protein overexpressing transgenic rats increases amyloid beta 42 levels and results in loss of memory retention.
    BMC Neurosci Volume: 17 Page(s): 46
    07/07/2016 Authors: Agca C; Klakotskaia D; Schachtman TR; Chan AW; Lah JJ; Agca Y
  • Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis.
    Nat Commun Volume: 7 Page(s): 11934
    06/21/2016 Authors: Iturria-Medina Y; Sotero RC; Toussaint PJ; Mateos-Prez JM; Evans AC; Alzheimers Disease Neuroimaging Initiative
  • 5-Hydroxymethylation-associated epigenetic modifiers of Alzheimer's disease modulate Tau-induced neurotoxicity.
    Hum Mol Genet Volume: 25 Page(s): 2437 - 2450
    06/15/2016 Authors: Bernstein AI; Lin Y; Street RC; Lin L; Dai Q; Yu L; Bao H; Gearing M; Lah JJ; Nelson PT
  • Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults.
    JAMA Neurol Volume: 73 Page(s): 721 - 732
    06/01/2016 Authors: Risacher SL; McDonald BC; Tallman EF; West JD; Farlow MR; Unverzagt FW; Gao S; Boustani M; Crane PK; Petersen RC
  • False-Positive Error Rates for Reliable Digit Span and Auditory Verbal Learning Test Performance Validity Measures in Amnestic Mild Cognitive Impairment and Early Alzheimer Disease.
    Arch Clin Neuropsychol Volume: 31 Page(s): 313 - 331
    06/01/2016 Authors: Loring DW; Goldstein FC; Chen C; Drane DL; Lah JJ; Zhao L; Larrabee GJ; Alzheimer's Disease Neuroimaging Initiative
  • Assessment of the genetic variance of late-onset Alzheimer's disease.
    Neurobiol Aging Volume: 41 Page(s): 200.e13 - 200.e20
    05/01/2016 Authors: Ridge PG; Hoyt KB; Boehme K; Mukherjee S; Crane PK; Haines JL; Mayeux R; Farrer LA; Pericak-Vance MA; Schellenberg GD
  • A Comparative Analysis of the Insoluble Brain Proteome in Alzheimer's Disease, Chronic Traumatic Encephalopathy and Frontotemporal Dementia
    Volume: 86
    04/05/2016 Authors: Hales C; Dammer E; Duong D; Webster J; Zeineddin A; Seyfried N; Lah J
  • A Comparative Analysis of the Insoluble Brain Proteome in Alzheimer's Disease, Chronic Traumatic Encephalopathy and Frontotemporal Dementia
    Volume: 86
    04/05/2016 Authors: Hales C; Dammer E; Duc D; Webster J; Zeineddin A; Seyfried N; Lah J
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    Acta Neuropathol Commun Volume: 4 Page(s): 14
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    Neurology Volume: 81 Page(s): 1945 - 1952
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    Neurobiol Dis Volume: 54 Page(s): 264 - 279
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  • Effects of hypertension and hypercholesterolemia on cognitive functioning in patients with alzheimer disease.
    Alzheimer Dis Assoc Disord Volume: 22 Page(s): 336 - 342
    01/01/2008 Authors: Goldstein FC; Ashley AV; Endeshaw YW; Hanfelt J; Lah JJ; Levey AI
  • Cognitive performance and plasma levels of homocysteine, vitamin B12, folate and lipids in patients with Alzheimer disease.
    Dement Geriatr Cogn Disord Volume: 26 Page(s): 384 - 390
    01/01/2008 Authors: Li L; Cao D; Desmond R; Rahman A; Lah JJ; Levey AI; Zamrini E
  • Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network.
    Mol Biol Cell Volume: 19 Page(s): 51 - 64
    01/01/2008 Authors: Shrivastava-Ranjan P; Faundez V; Fang G; Rees H; Lah JJ; Levey AI; Kahn RA
  • Neuronal LR11/sorLA expression is reduced in mild cognitive impairment.
    Ann Neurol Volume: 62 Page(s): 640 - 647
    12/01/2007 Authors: Sager KL; Wuu J; Leurgans SE; Rees HD; Gearing M; Mufson EJ; Levey AI; Lah JJ
  • Evidence of shared risk for Alzheimer's disease and Parkinson's disease using family history.
    Neurogenetics Volume: 8 Page(s): 263 - 270
    11/01/2007 Authors: Rosen AR; Steenland NK; Hanfelt J; Factor SA; Lah JJ; Levey AI
  • PARK10 candidate RNF11 is expressed by vulnerable neurons and localizes to Lewy bodies in Parkinson disease brain.
    J Neuropathol Exp Neurol Volume: 66 Page(s): 955 - 964
    10/01/2007 Authors: Anderson LR; Betarbet R; Gearing M; Gulcher J; Hicks AA; Stefnsson K; Lah JJ; Levey AI
  • Influence of sleep disordered breathing on cognitive functioning among elderly with cognitive compromise
    ARCHIVES OF CLINICAL NEUROPSYCHOLOGY Volume: 22 Page(s): 817 - 817
    09/01/2007 Authors: Yamout KZ; Bliwise DL; Goldstein FC; Wood-Siverio C; Lah JJ; Levey A
  • Daytime sleepiness and functional impairment in Alzheimer disease.
    Am J Geriatr Psychiatry Volume: 15 Page(s): 620 - 626
    07/01/2007 Authors: Lee JH; Bliwise DL; Ansari FP; Goldstein FC; Cellar JS; Lah JJ; Levey AI
  • Clinical and neuropathologic findings in a case of posterior cortical atrophy (PCA)
    Volume: 66 Page(s): 422 - 422
    05/01/2007 Authors: Gearing M; Brat DJ; Hunter SB; Cooper DS; Tehrani M; Lah JJ
  • Clinical and neuropathologic findings in a case of posterior cortical atrophy (PCA)
    Volume: 21 Page(s): A22 - A22
    04/01/2007 Authors: Gearing M; Brat DJ; Hunter SB; Cooper DS; Tehrani M; Lah JJ
  • Plaque amyloid per se plays no detectable role in timing of onset or initial severity of cognitive dysfunction in a mouse model of Alzheimer's
    Volume: 68 Page(s): A188 - A189
    03/20/2007 Authors: Gandy S; Lah J; Walker L; Kufahamu T; Pedrini S; Gieringer T; Levy E; Levey A; Abel T; Ehrlich M
  • The role of LR11/SORL1 in Alzheimer's disease pathogenesis
    Volume: 62 Page(s): S7 - S7
    01/01/2007 Authors: Lah JJ; Offe K; Dodson SE; Sager KL; Khoogar L; Levey AI
  • Changes in expression and distribution of LR11/Sorla distinguish between sporadic and genetic forms of Alzheimer's disease
    Volume: 60 Page(s): 642 - 642
    11/01/2006 Authors: Lah JJ; Dodson SE; Khoogar L; Mufson EJ; Levey AI
  • LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease.
    J Neuropathol Exp Neurol Volume: 65 Page(s): 866 - 872
    09/01/2006 Authors: Dodson SE; Gearing M; Lippa CF; Montine TJ; Levey AI; Lah JJ
  • Mild cognitive impairment: an opportunity to identify patients at high risk for progression to Alzheimer's disease.
    Clin Ther Volume: 28 Page(s): 991 - 1001
    07/01/2006 Authors: Levey A; Lah J; Goldstein F; Steenland K; Bliwise D
  • Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel gamma-secretase substrates.
    Mol Neurodegener Volume: 1 Page(s): 3
    06/12/2006 Authors: Nyborg AC; Ladd TB; Zwizinski CW; Lah JJ; Golde TE
  • The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments.
    J Neurosci Volume: 26 Page(s): 1596 - 1603
    02/01/2006 Authors: Offe K; Dodson SE; Shoemaker JT; Fritz JJ; Gearing M; Levey AI; Lah JJ
  • Merger of laser capture microdissection and mass spectrometry: a window into the amyloid plaque proteome.
    Methods Enzymol Volume: 412 Page(s): 77 - 93
    01/01/2006 Authors: Gozal YM; Cheng D; Duong DM; Lah JJ; Levey AI; Peng J
  • LR11 regulates intracellular amyloid precursor protein traffic and amyloid accumulation in Alzheimer's disease
    Volume: 58
    12/01/2005 Authors: Lah JJ; Dodson SE; Offe K; Shoemaker JT; Levey AI
  • Severe frontotemporal glial pathology and mild hippocampal degeneration associated with the P301L MAPT mutation: Study of a previously unreported family.
    Volume: 64 Page(s): 434 - 434
    05/01/2005 Authors: Spina S; Murrell JR; Gearing M; Levey A; Mirra S; Yamaguchi K; Ghetti B; Lah J
  • Concomitant Alzheimer's disease and frontotemporal dementia-motor neuron disease subtype: A common neuropathologic phenomenon.
    Volume: 64 Page(s): 433 - 433
    05/01/2005 Authors: Gearing M; Lah JJ; Levey AI
  • Hypertension and cognitive performance in African Americans with Alzheimer disease.
    Neurology Volume: 64 Page(s): 899 - 901
    03/08/2005 Authors: Goldstein FC; Ashley AV; Freedman LJ; Penix L; Lah JJ; Hanfelt J; Levey AI
  • Feasibility of ambulatory overnight oximetry in consecutive patients in a dementia clinic.
    J Am Geriatr Soc Volume: 53 Page(s): 545 - 546
    03/01/2005 Authors: Bliwise DL; Lee J-H; Wood-Siverio C; Cellar JS; Lah JJ; Levey AI
  • Common pattern of deficit in a multinational MCI cohort identified by objective computerized cognitive assessment
    INTERNATIONAL PSYCHOGERIATRICS Volume: 17 Page(s): 252 - 253
    01/01/2005 Authors: Dwolatzky T; Doniger G; Simon E; Goldstein F; Levey A; Lah J
  • Daytime sleepiness associated with cognitive and functional impairments in Alzheimer's disease (AD)
    Volume: 28 Page(s): A347 - A347
    01/01/2005 Authors: Lee JH; Bliwise DL; Ansari FP; Goldstein FG; Cellar JS; Lah JJ; Levey AI
  • Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection.
    J Biol Chem Volume: 279 Page(s): 37061 - 37068
    08/27/2004 Authors: Liao L; Cheng D; Wang J; Duong DM; Losik TG; Gearing M; Rees HD; Lah JJ; Levey AI; Peng J
  • Loss of apolipoprotein E receptor LR11 in Alzheimer disease.
    Arch Neurol Volume: 61 Page(s): 1200 - 1205
    08/01/2004 Authors: Scherzer CR; Offe K; Gearing M; Rees HD; Fang G; Heilman CJ; Schaller C; Bujo H; Levey AI; Lah JJ
  • Examining the role of the APOE receptor LR11 in the etiopathology of Alzheimer's disease
    Volume: 25 Page(s): S441 - S441
    07/01/2004 Authors: Dodson SE; Offe K; Carter SC; Shoemaker JT; Fan GF; Lah JJ; Levey AI
  • Activity-dependent calcium entry in synaptosomes regulates app metabolism and A-beta production
    Volume: 25 Page(s): S78 - S78
    07/01/2004 Authors: Cook DG; Lab JJ; Wang J; Zhu P; Yang YX; Duerson KC
  • Intermittent hypoxic insults occurring during a period of critical brain development reduce the expression of insoluble beta amyloid within the hippocampus
    Volume: 25 Page(s): S166 - S166
    07/01/2004 Authors: Jones KA; Carter S; Shoemaker JT; Solomon IG; Lah J; Levey A; Decker MJ
  • Quantification of LR11 expression in mild cognitive impairment, a human model for early Alzheimer's disease
    Volume: 25 Page(s): S439 - S439
    07/01/2004 Authors: Sager KL; Lah JJ; Levey AI; Rees HD; Mufson EJ; Bennett DA; Wuu J; Leurgans S
  • The "Mini-Cog" as a screen for dementia: Validation in an African American population
    Volume: 25 Page(s): S131 - S132
    07/01/2004 Authors: Ashley AV; Flacker J; Goldstein FC; Freedman LJ; Lah JJ; Levey AI
  • Effect of targeted domain deletions on LR11-mediated regulation of extracellular A beta levels
    Volume: 25 Page(s): S440 - S440
    07/01/2004 Authors: Offe K; Williams TJ; Fang GF; Lah JJ; Levey AI
  • Functional abilities in patients with mild cognitive impairment versus Alzheimer's disease and normal controls
    Volume: 25 Page(s): S100 - S100
    07/01/2004 Authors: Goldstein FC; Ashley AV; Freedman LJ; Cellar J; Harrison J; Lah JJ; Levey AI
  • Reduced expression of the multifunctional apolipoprotein E receptor LR11 plays an important role in Alzheimer's disease pathogenesis.
    Volume: 63 Page(s): 553 - 553
    05/01/2004 Authors: Gearing M; Lah JJ; Sager KL; Offer K; Dodson SE; Carter SC; Bennett DA; Mufson EJ; Levey AI
  • Munc18 interacting proteins: ADP-ribosylation factor-dependent coat proteins that regulate the traffic of beta-Alzheimer's precursor protein.
    J Biol Chem Volume: 278 Page(s): 36032 - 36040
    09/19/2003 Authors: Hill K; Li Y; Bennett M; McKay M; Zhu X; Shern J; Torre E; Lah JJ; Levey AI; Kahn RA
  • Endoproteolysis of beta-secretase (beta-site amyloid precursor protein-cleaving enzyme) within its catalytic domain. A potential mechanism for regulation.
    J Biol Chem Volume: 278 Page(s): 17141 - 17149
    05/09/2003 Authors: Huse JT; Byant D; Yang Y; Pijak DS; D'Souza I; Lah JJ; Lee VM-Y; Doms RW; Cook DG
  • Rab11a and myosin Vb regulate recycling of the M4 muscarinic acetylcholine receptor.
    J Neurosci Volume: 22 Page(s): 9776 - 9784
    11/15/2002 Authors: Volpicelli LA; Lah JJ; Fang G; Goldenring JR; Levey AI
  • BACE activity is regulated by an internal loop region whose sequence resembles the beta-secretase cleavage site of the amyloid precursor protein
    NEUROBIOLOGY OF AGING Volume: 23 Page(s): S182 - S183
    07/01/2002 Authors: McGraw W; Lah J; Levey A
  • Effects of manipulating endosomal traffic on amyloid precursor protein metabolism and amyloid beta peptide secretion
    NEUROLOGY Volume: 58 Page(s): A362 - A362
    04/09/2002 Authors: Lah JJ; Levey AI
  • Notch signaling inhibits PC12 cell neurite outgrowth via RBP-J-dependent and -independent mechanisms.
    Dev Neurosci Volume: 24 Page(s): 79 - 88
    01/01/2002 Authors: Levy OA; Lah JJ; Levey AI
  • Rab5-dependent trafficking of the m4 muscarinic acetylcholine receptor to the plasma membrane, early endosomes, and multivesicular bodies.
    J Biol Chem Volume: 276 Page(s): 47590 - 47598
    12/14/2001 Authors: Volpicelli LA; Lah JJ; Levey AI
  • Multiple effects of aspartate mutant presenilin 1 on the processing and trafficking of amyloid precursor protein.
    J Biol Chem Volume: 276 Page(s): 43343 - 43350
    11/16/2001 Authors: Kim SH; Leem JY; Lah JJ; Slunt HH; Levey AI; Thinakaran G; Sisodia SS
  • M1 and M4 subtypes of muscarinic receptors traffic through distinct endosomal compartments in PC12 cells
    LIFE SCIENCES Volume: 68 Page(s): 2623 - 2623
    04/27/2001 Authors: Volpicelli LA; Lah JJ; Levey AI
  • The regulation of presenilin-1 by nerve growth factor.
    J Neurochem Volume: 76 Page(s): 679 - 689
    02/01/2001 Authors: Counts SE; Lah JJ; Levey AI
  • Large-scale gene expression in Alzheimer's disease lymphoblasts
    ANNALS OF NEUROLOGY Volume: 48 Page(s): 429 - 429
    09/01/2000 Authors: Scherzer CR; Lah J; Bennett-Desmelik JA; Fang G; Counts S; Greenamyre JT; Levey AI
  • Endogenous presenilin-1 targets to endocytic rather than biosynthetic compartments.
    Mol Cell Neurosci Volume: 16 Page(s): 111 - 126
    08/01/2000 Authors: Lah JJ; Levey AI
  • Subcellular localization of presenilins: association with a unique membrane pool in cultured cells.
    Neurobiol Dis Volume: 7 Page(s): 99 - 117
    04/01/2000 Authors: Kim SH; Lah JJ; Thinakaran G; Levey A; Sisodia SS
  • Localization and characterization of speech arrest during transcranial magnetic stimulation.
    Clin Neurophysiol Volume: 110 Page(s): 1073 - 1079
    06/01/1999 Authors: Epstein CM; Meador KJ; Loring DW; Wright RJ; Weissman JD; Sheppard S; Lah JJ; Puhalovich F; Gaitan L; Davey KR
  • Muscarinic activation of MAPK in PC12 cells
    LIFE SCIENCES Volume: 64 Page(s): 566 - 566
    01/08/1999 Authors: Berkeley JL; Lah JJ; Levey AI
  • Differential effects of transforming growth factor-beta(s) and glial cell line-derived neurotrophic factor on gene expression of presenilin-1 in human post-mitotic neurons and astrocytes.
    Neuroscience Volume: 93 Page(s): 1041 - 1049
    01/01/1999 Authors: Ren RF; Lah JJ; Diehlmann A; Kim ES; Hawver DB; Levey AI; Beyreuther K; Flanders KC
  • Regulation of presenilin-1 during neuronotypic differentiation of PC12 cells
    BRAIN PATHOLOGY Volume: 8 Page(s): 579 - 579
    07/01/1998 Authors: Counts SE; Lah JJ; Levey AI
  • Presenilin-1 protein expression in familial and sporadic Alzheimer's disease.
    Ann Neurol Volume: 41 Page(s): 742 - 753
    06/01/1997 Authors: Levey AI; Heilman CJ; Lah JJ; Nash NR; Rees HD; Wakai M; Mirra SS; Rye DB; Nochlin D; Bird TD
  • Light and electron microscopic localization of presenilin-1 in primate brain.
    J Neurosci Volume: 17 Page(s): 1971 - 1980
    03/15/1997 Authors: Lah JJ; Heilman CJ; Nash NR; Rees HD; Yi H; Counts SE; Levey AI
  • Optimum stimulus parameters for lateralized suppression of speech with magnetic brain stimulation.
    Neurology Volume: 47 Page(s): 1590 - 1593
    12/01/1996 Authors: Epstein CM; Lah JJ; Meador K; Weissman JD; Gaitan LE; Dihenia B
  • Synaptophysin has a selective distribution in early endosomes of PC12 cells.
    J Neurocytol Volume: 22 Page(s): 92 - 101
    02/01/1993 Authors: Lah JJ; Burry RW
  • Neuronotypic differentiation results in reduced levels and altered distribution of synaptophysin in PC12 cells.
    J Neurochem Volume: 60 Page(s): 503 - 512
    02/01/1993 Authors: Lah JJ; Burry RW
  • GAP-43 distribution is correlated with development of growth cones and presynaptic terminals.
    J Neurocytol Volume: 21 Page(s): 413 - 425
    06/01/1992 Authors: Burry RW; Lah JJ; Hayes DM
  • Redistribution of GAP-43 during growth cone development in vitro; immunocytochemical studies.
    J Neurocytol Volume: 20 Page(s): 133 - 144
    02/01/1991 Authors: Burry RW; Lah JJ; Hayes DM
  • A neutral pH silver development method for the visualization of 1-nanometer gold particles in pre-embedding electron microscopic immunocytochemistry.
    J Histochem Cytochem Volume: 38 Page(s): 503 - 508
    04/01/1990 Authors: Lah JJ; Hayes DM; Burry RW
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