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Profile

John Calvert PhD

  • Department of Surgery
    Associate Professor
  • (404) 251-0663
  • jcalver@emory.edu
Head shot of John Calvert

Overview

Dr. Calvert's primary research focuses on signaling cascades in the setting of acute myocardial ischemia-reperfusion injury and heart failure. His ultimate goal is to identify novel therapeutic targets that will lead to new treatment options to improve the quality of life of patients suffering from a heart attack or that are having heart failure.

Grant awards from the National Institutes of Health and the American Diabetes Association have contributed to supporting Dr. Calvert's research since he established his independent laboratory at Emory in 2008, and his findings have been published in such high impact journals as Circulation, Circulation Research, and Atherosclerosis, Thrombosis, and Vascular Biology.

Academic Appointment

  • Associate Professor, Department of Surgery, Emory University School of Medicine

Education

Degrees

  • Doctor of Philosophy from Loma Linda University School of Medicine
  • BS from University of Mississippi

Research

Focus

  • Studies of the mechanisms of cardioprotection in the setting of acute myocardial ischemia-reperfusion injury and heart failure.

    Investigations in Dr. Calvert's lab have included evaluations of the cardioprotective signaling mechanisms of hydrogen sulfide in heart failure and the diabetic heart, as well as examinations of the cardioprotective signaling mechanisms of exercise.

Publications

  • The Cardioprotective Role of Neutrophil-Specific STING in Myocardial Ischemia/Reperfusion Injury.

    09/11/2024 Authors: Brockman ML; Scruggs TA; Wang L; Kabboul G; Calvert JW; Levit RD
  • Effects of protein glycation and protective mechanisms against glycative stress.
    Curr Opin Pharmacol Volume: 76 Page(s): 102464
    06/01/2024 Authors: Najjar JA; Calvert JW
  • BAK contributes critically to necrosis and infarct generation during reperfused myocardial infarction.
    J Mol Cell Cardiol Volume: 184 Page(s): 1 - 12
    11/01/2023 Authors: Qin D; Jia XF; Hanna A; Lee J; Pekson R; Elrod JW; Calvert JW; Frangogiannis NG; Kitsis RN
  • Cardiac Lymphatic Insufficiency Leads to Diastolic Dysfunction Via Myocardial Morphologic Change.
    JACC Basic Transl Sci Volume: 8 Page(s): 958 - 972
    08/01/2023 Authors: Pu Z; Shimizu Y; Hayashi T; Che Y; Suzuki J; Tsuzuki K; Narita S; Shibata R; Calvert JW; Murohara T
  • Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis.
    Volume: 147 Page(s): 1823 - 1842
    06/13/2023 Authors: Cho K-W; Andrade M; Bae S; Kim S; Eyun Kim J; Jang EY; Lee S; Husain A; Sutliff RL; Calvert JW
  • Hydrogen Sulfide Attenuates Lymphedema Via the Induction of Lymphangiogenesis Through a PI3K/Akt-Dependent Mechanism.
    J Am Heart Assoc Volume: 11 Page(s): e026889
    11/01/2022 Authors: Suzuki J; Shimizu Y; Hayashi T; Che Y; Pu Z; Tsuzuki K; Narita S; Shibata R; Ishii I; Calvert JW
  • Mitochondrial H2S Regulates BCAA Catabolism in Heart Failure.
    Circ Res Volume: 131 Page(s): 222 - 235
    07/22/2022 Authors: Li Z; Xia H; Sharp TE; LaPenna KB; Elrod JW; Casin KM; Liu K; Calvert JW; Chau VQ; Salloum FN
  • A phospholipid mimetic targeting LRH-1 ameliorates colitis.
    Cell Chem Biol Volume: 29 Page(s): 1174 - 1186.e7
    07/21/2022 Authors: Mays SG; D'Agostino EH; Flynn AR; Huang X; Wang G; Liu X; Millings EJ; Okafor CD; Patel A; Cato ML
  • Remuscularization with triiodothyronine and 1-blocker therapy reverses post-ischemic left ventricular dysfunction and adverse remodeling.
    Sci Rep Volume: 12 Page(s): 8852
    05/25/2022 Authors: Bogush N; Tan L; Naqvi E; Calvert JW; Graham RM; Taylor WR; Naqvi N; Husain A
  • Guidelines for in vivo mouse models of myocardial infarction.
    Am J Physiol Heart Circ Physiol Volume: 321 Page(s): H1056 - H1073
    12/01/2021 Authors: Lindsey ML; Brunt KR; Kirk JA; Kleinbongard P; Calvert JW; de Castro Brs LE; DeLeon-Pennell KY; Del Re DP; Frangogiannis NG; Frantz S
  • DJ-1 attenuates the glycation of mitochondrial complex I and complex III in the post-ischemic heart.
    Sci Rep Volume: 11 Page(s): 19408
    09/30/2021 Authors: Pantner Y; Polavarapu R; Chin L-S; Li L; Shimizu Y; Calvert JW
  • Dynamic Regulation of Cysteine Oxidation and Phosphorylation in Myocardial Ischemia-Reperfusion Injury.
    Cells Volume: 10
    09/11/2021 Authors: Casin KM; Calvert JW
  • Adverse Effect of Circadian Rhythm Disorder on Reparative Angiogenesis in Hind Limb Ischemia.
    J Am Heart Assoc Volume: 10 Page(s): e020896
    08/17/2021 Authors: Tsuzuki K; Shimizu Y; Suzuki J; Pu Z; Yamaguchi S; Fujikawa Y; Kato K; Ohashi K; Takefuji M; Bando YK
  • Important Role of Concomitant Lymphangiogenesis for Reparative Angiogenesis in Hindlimb Ischemia.
    Arterioscler Thromb Vasc Biol Volume: 41 Page(s): 2006 - 2018
    06/01/2021 Authors: Pu Z; Shimizu Y; Tsuzuki K; Suzuki J; Hayashida R; Kondo K; Fujikawa Y; Unno K; Ohashi K; Takefuji M
  • Harnessing the Benefits of Endogenous Hydrogen Sulfide to Reduce Cardiovascular Disease.
    Antioxidants (Basel) Volume: 10
    03/04/2021 Authors: Casin KM; Calvert JW
  • Thyroid hormone plus dual-specificity phosphatase-5 siRNA increases the number of cardiac muscle cells and improves left ventricular contractile function in chronic doxorubicin-injured hearts.
    Theranostics Volume: 11 Page(s): 4790 - 4808
    01/01/2021 Authors: Tan L; Bogush N; Naqvi E; Calvert JW; Graham RM; Taylor WR; Naqvi N; Husain A
  • DUSP5 expression in left ventricular cardiomyocytes of young hearts regulates thyroid hormone (T3)-induced proliferative ERK1/2 signaling.
    Sci Rep Volume: 10 Page(s): 21918
    12/14/2020 Authors: Bogush N; Tan L; Naib H; Faizullabhoy E; Calvert JW; Iismaa SE; Gupta A; Ramchandran R; Martin DIK; Graham RM
  • DJ-1 Deficiency Impairs Post-Ischemic Cardiac Fatty Acid Oxidation
    Volume: 127
    07/31/2020 Authors: Casin KM; Pantner Y; Shimizu Y; Polavarapu R; Chin L-S; Li L; Calvert JW
  • Role of DJ-1 in Modulating Glycative Stress in Heart Failure.
    J Am Heart Assoc Volume: 9 Page(s): e014691
    02/18/2020 Authors: Shimizu Y; Nicholson CK; Polavarapu R; Pantner Y; Husain A; Naqvi N; Chin L-S; Li L; Calvert JW
  • Development of the First Low Nanomolar Liver Receptor Homolog-1 Agonist through Structure-guided Design.
    J Med Chem Volume: 62 Page(s): 11022 - 11034
    12/26/2019 Authors: Mays SG; Flynn AR; Cornelison JL; Okafor CD; Wang H; Wang G; Huang X; Donaldson HN; Millings EJ; Polavarapu R
  • Redox activation of JNK22 mediates thyroid hormone-stimulated proliferation of neonatal murine cardiomyocytes.
    Sci Rep Volume: 9 Page(s): 17731
    11/27/2019 Authors: Tan L; Bogush N; Naib H; Perry J; Calvert JW; Martin DIK; Graham RM; Naqvi N; Husain A
  • Dusp5 Triggers and Maintains Cell Cycle Block in Postnatal Cardiomyocytes
    Volume: 140
    11/19/2019 Authors: Bogush N; Tan L; Naib H; Calvert JW; Martin D; Graham RM; Husain A; Naqvi N
  • DJ-1 Confers Protection Against Ischemic Injury by Preserving the Activity of Thioredoxin
    Volume: 125
    08/02/2019 Authors: Pantner Y; Shimizu Y; Polavarapu R; Li L; Chin L-S; Calvert J
  • DJ-1 Preserves Mitochondrial Function in the Ischemic Heart by Reducing the Glycation of Complex I
    Volume: 125
    08/02/2019 Authors: Pantner Y; Shimizu Y; Polavarapu R; Li L; Chin L-S; Calvert J
  • Inducing Expression of the Cleaved Form of DJ-1 Attenuates Ischemic-Induced Heart Failure
    Volume: 124 Page(s): 116 - 116
    11/01/2018 Authors: Pantner Y; Shimizu Y; Nicholson C; Li L; Chin L-S; Calvert J
  • Impact of Lymphangiogenesis on Cardiac Remodeling After Ischemia and Reperfusion Injury.
    J Am Heart Assoc Volume: 7 Page(s): e009565
    10/02/2018 Authors: Shimizu Y; Polavarapu R; Eskla K-L; Pantner Y; Nicholson CK; Ishii M; Brunnhoelzl D; Mauria R; Husain A; Naqvi N
  • Cardiac hypertrophy limits infarct expansion after myocardial infarction in mice.
    Sci Rep Volume: 8 Page(s): 6114
    04/17/2018 Authors: Iismaa SE; Li M; Kesteven S; Wu J; Chan AY; Holman SR; Calvert JW; Haq AU; Nicks AM; Naqvi N
  • Hydrogen sulfide regulates cardiac mitochondrial biogenesis via the activation of AMPK.
    J Mol Cell Cardiol Volume: 116 Page(s): 29 - 40
    03/01/2018 Authors: Shimizu Y; Polavarapu R; Eskla K-L; Nicholson CK; Koczor CA; Wang R; Lewis W; Shiva S; Lefer DJ; Calvert JW
  • Diallyl Trisulfide Augments Ischemia-Induced Angiogenesis via an Endothelial Nitric Oxide Synthase-Dependent Mechanism.
    Circ J Volume: 81 Page(s): 870 - 878
    05/25/2017 Authors: Hayashida R; Kondo K; Morita S; Unno K; Shintani S; Shimizu Y; Calvert JW; Shibata R; Murohara T
  • PPAR attenuates hypoxia-induced hypertrophic transcriptional pathways in the heart.
    Pulm Circ Volume: 7 Page(s): 98 - 107
    03/01/2017 Authors: Chaudhry A; Carthan KA; Kang B-Y; Calvert J; Sutliff RL; Michael Hart C
  • Exercise training provides cardioprotection by activating and coupling endothelial nitric oxide synthase via a 3-adrenergic receptor-AMP-activated protein kinase signaling pathway.
    Med Gas Res Volume: 7 Page(s): 1 - 8
    01/01/2017 Authors: Barr LA; Lambert JP; Shimizu Y; Barouch LA; Naqvi N; Calvert JW
  • Therapeutic Lymphangiogenesis Ameliorates Cardiac Dysfunction in the Setting of Ischemic-induced Heart Failure
    Volume: 134
    11/18/2016 Authors: Shimizu Y; Polavarapu R; Murohara T; Calvert J
  • DJ-1 protects the heart against ischemia-reperfusion injury by regulating mitochondrial fission.
    J Mol Cell Cardiol Volume: 97 Page(s): 56 - 66
    08/01/2016 Authors: Shimizu Y; Lambert JP; Nicholson CK; Kim JJ; Wolfson DW; Cho HC; Husain A; Naqvi N; Chin L-S; Li L
  • Hydrogen Sulfide Promotes Mitochondrial Biogenesis Through the Regulation of AMP-activated Protein Kinase
    Volume: 119
    07/22/2016 Authors: Shimizu Y; Polavarapu R; Calvert J
  • DJ-1 Gene Therapy Opposes the Development of Ischemic Heart Failure
    Volume: 119
    07/22/2016 Authors: Shimizu Y; Sha D; Chin L-S; Li L; Calvert J
  • Leukocyte-Expressed 2-Adrenergic Receptors Are Essential for Survival After Acute Myocardial Injury.
    Circulation Volume: 134 Page(s): 153 - 167
    07/12/2016 Authors: Grisanti LA; Gumpert AM; Traynham CJ; Gorsky JE; Repas AA; Gao E; Carter RL; Yu D; Calvert JW; Garca AP
  • IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction.
    Proc Natl Acad Sci U S A Volume: 113 Page(s): 6949 - 6954
    06/21/2016 Authors: Tejada T; Tan L; Torres RA; Calvert JW; Lambert JP; Zaidi M; Husain M; Berce MD; Naib H; Pejler G
  • Recycling KATP channels for cardioprotection.
    Am J Physiol Heart Circ Physiol Volume: 310 Page(s): H1381 - H1382
    06/01/2016 Authors: Shimizu Y; Calvert JW
  • Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency.
    J Bone Miner Res Volume: 31 Page(s): 949 - 963
    05/01/2016 Authors: Grassi F; Tyagi AM; Calvert JW; Gambari L; Walker LD; Yu M; Robinson J; Li J-Y; Lisignoli G; Vaccaro C
  • Sodium Sulfide Attenuates Ischemic-Induced Heart Failure by Enhancing Proteasomal Function in an Nrf2-Dependent Manner.
    Circ Heart Fail Volume: 9 Page(s): e002368
    04/01/2016 Authors: Shimizu Y; Nicholson CK; Lambert JP; Barr LA; Kuek N; Herszenhaut D; Tan L; Murohara T; Hansen JM; Husain A
  • Adipose-Derived Stem Cells Induce Angiogenesis via Microvesicle Transport of miRNA-31.
    Stem Cells Transl Med Volume: 5 Page(s): 440 - 450
    04/01/2016 Authors: Kang T; Jones TM; Naddell C; Bacanamwo M; Calvert JW; Thompson WE; Bond VC; Chen YE; Liu D
  • Angiotensin type 2-receptor (AT2R) activation induces hypotension in apolipoprotein E-deficient mice by activating peroxisome proliferator-activated receptor-.
    Am J Cardiovasc Dis Volume: 6 Page(s): 118 - 128
    01/01/2016 Authors: Li M; Tejada T; Lambert JP; Nicholson CK; Yahiro E; Ambai VT; Ali SF; Bradley EW; Graham RM; Dell'Italia LJ
  • DJ-1/Park7 Protects the Heart Against Ischemia-reperfusion Injury Through the Modulation of SUMOylation (Best of Basic Science Abstract)
    Volume: 132
    11/10/2015 Authors: Shimizu Y; Barr L; Fields T; Calvert JW
  • Cardiomyocytes Replicate and their Numbers Increase in Young Hearts.
    Cell Volume: 163 Page(s): 783 - 784
    11/05/2015 Authors: Naqvi N; Singh R; Iismaa SE; Li M; Calvert JW; Martin DIK; Harvey RP; Graham RM; Husain A
  • Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome.
    Am J Physiol Heart Circ Physiol Volume: 309 Page(s): H82 - H92
    07/01/2015 Authors: Polhemus DJ; Bradley JM; Islam KN; Brewster LP; Calvert JW; Tao Y-X; Chang CC; Pipinos II; Goodchild TT; Lefer DJ
  • Hydrogen sulfide attenuates high fat diet-induced cardiac dysfunction via the suppression of endoplasmic reticulum stress.
    Nitric Oxide Volume: 46 Page(s): 145 - 156
    04/30/2015 Authors: Barr LA; Shimizu Y; Lambert JP; Nicholson CK; Calvert JW
  • Adipose-Derived Regenerative Cells for Cardiovascular Regeneration--A Novel Therapy for the Cardiac Conduction System.
    Circ J Volume: 79 Page(s): 2555 - 2556
    01/01/2015 Authors: Shimizu Y; Calvert JW; Murohara T
  • Nox2 targets SERCA in response to a high fat high sugar diet.
    J Mol Cell Cardiol Volume: 72 Page(s): 228 - 230
    07/01/2014 Authors: Calvert JW
  • Nrf2 signaling is essential for hydrogen sulfide mediated cardioprotection in the setting of ischemic-induced heart failure
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY Volume: 39 Page(s): S3 - S3
    05/30/2014 Authors: Calvert JW
  • A proliferative burst during preadolescence establishes the final cardiomyocyte number.
    Cell Volume: 157 Page(s): 795 - 807
    05/08/2014 Authors: Naqvi N; Li M; Calvert JW; Tejada T; Lambert JP; Wu J; Kesteven SH; Holman SR; Matsuda T; Lovelock JD
  • Nitrite therapy improves left ventricular function during heart failure via restoration of nitric oxide-mediated cytoprotective signaling.
    Circ Res Volume: 114 Page(s): 1281 - 1291
    04/11/2014 Authors: Bhushan S; Kondo K; Polhemus DJ; Otsuka H; Nicholson CK; Tao Y-X; Huang H; Georgiopoulou VV; Murohara T; Calvert JW
  • Effects of a novel sustained release sodium nitrite formulation on critical limb ischemia in the setting of metabolic syndrome
    FASEB JOURNAL Volume: 28
    04/01/2014 Authors: Bradley J; Goodchild T; Chang C; Polhemus D; Otsuka H; Sweet M; Brown K; Robinson S; Brewster L; Calvert J
  • Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent.
    Proc Natl Acad Sci U S A Volume: 111 Page(s): 3182 - 3187
    02/25/2014 Authors: King AL; Polhemus DJ; Bhushan S; Otsuka H; Kondo K; Nicholson CK; Bradley JM; Islam KN; Calvert JW; Tao Y-X
  • Treating percutaneous coronary intervention-related myocardial injury with metformin.
    Cardiology Volume: 127 Page(s): 130 - 132
    01/01/2014 Authors: Calvert JW
  • Hydrogen sulfide provides cardioprotection against myocardial/ischemia reperfusion injury in the diabetic state through the activation of the RISK pathway.
    Med Gas Res Volume: 4 Page(s): 20
    01/01/2014 Authors: Lambert JP; Nicholson CK; Amin H; Amin S; Calvert JW
  • Discoveries of hydrogen sulfide as a novel cardiovascular therapeutic.
    Circ J Volume: 78 Page(s): 2111 - 2118
    01/01/2014 Authors: Barr LA; Calvert JW
  • The cardioprotective actions of hydrogen sulfide in acute myocardial infarction and heart failure.
    Scientifica (Cairo) Volume: 2014 Page(s): 768607
    01/01/2014 Authors: Polhemus DJ; Calvert JW; Butler J; Lefer DJ
  • Beta-3 Adrenergic Receptor Deficiency Reverses the Cardioprotective Effects of Exercise by Attenuating AMPK Phosphorylation and eNOS Coupling
    CIRCULATION Volume: 128
    11/26/2013 Authors: Lambert JP; Nicholson CK; Calvert JW
  • Genetic Deficiency of the Hydrogen Sulfide H2S Enzyme, Cystathionine Gamma-lyase (CSE) Results in eNOS Uncoupling and Exacerbated Myocardial Injury: Evidence for Cross Talk Between NO and H2S Signaling
    CIRCULATION Volume: 128
    11/26/2013 Authors: King AI; Bushan S; Kondo K; Nicholson C; Polhemus D; Calvert JW; Dugas T; Hebert V; Wang R; Lefer DJ
  • Sodium Nitrite Improves Left Ventricular Function During Heart Failure via Cytoprotective Signaling and Angiogenesis
    CIRCULATION Volume: 128
    11/26/2013 Authors: Bhushan S; Kondo K; Polhemus D; Nicholson C; Tao Y-X; Huang H; Murohara T; Georgiopoulou VV; Calvert JW; Butler J
  • Chronic exercise downregulates myocardial myoglobin and attenuates nitrite reductase capacity during ischemia-reperfusion.
    J Mol Cell Cardiol Volume: 64 Page(s): 1 - 10
    11/01/2013 Authors: Nicholson CK; Lambert JP; Chow C-W; Lefer DJ; Calvert JW
  • Hydrogen sulfide attenuates cardiac dysfunction after heart failure via induction of angiogenesis.
    Circ Heart Fail Volume: 6 Page(s): 1077 - 1086
    09/01/2013 Authors: Polhemus D; Kondo K; Bhushan S; Bir SC; Kevil CG; Murohara T; Lefer DJ; Calvert JW
  • Deficiency of DJ-1 Leads to Increased Injury following Myocardial Ischemia by Enhancing Apoptosis and Oxidative Stress
    CIRCULATION RESEARCH Volume: 113
    08/01/2013 Authors: Lambert JP; Nicholson CK; Calvert JW
  • Role of -adrenergic receptors and nitric oxide signaling in exercise-mediated cardioprotection.
    Physiology (Bethesda) Volume: 28 Page(s): 216 - 224
    07/01/2013 Authors: Calvert JW; Lefer DJ
  • Hydrogen sulfide preconditions the db/db diabetic mouse heart against ischemia-reperfusion injury by activating Nrf2 signaling in an Erk-dependent manner.
    Am J Physiol Heart Circ Physiol Volume: 304 Page(s): H1215 - H1224
    05/01/2013 Authors: Peake BF; Nicholson CK; Lambert JP; Hood RL; Amin H; Amin S; Calvert JW
  • Chronic sodium nitrite (NaNO2) therapy attenuates the severity of pressure overload induced heart failure in mice
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY Volume: 31 Page(s): S30 - S30
    04/15/2013 Authors: Bhushan S; Kondo K; Polhemus D; Ostuka H; King AL; Calvert JW; Lefer DJ
  • Genetic deficiency of the H2S producing enzyme, cystathionine gamma-iyase (CSE) results in exacerbated myocardial ischemia/reperfusion (MI/R) injury: Role of eNOS dysfunction and decreased nitrite levels
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY Volume: 31 Page(s): S31 - S31
    04/15/2013 Authors: King AL; Bushan S; Kondo K; Nicholson C; Polhemus D; Wang R; Calvert J; Lefer D
  • Thioredoxin 1 is essential for sodium sulfide-mediated cardioprotection in the setting of heart failure.
    Arterioscler Thromb Vasc Biol Volume: 33 Page(s): 744 - 751
    04/01/2013 Authors: Nicholson CK; Lambert JP; Molkentin JD; Sadoshima J; Calvert JW
  • HS protects against pressure overload-induced heart failure via upregulation of endothelial nitric oxide synthase.
    Circulation Volume: 127 Page(s): 1116 - 1127
    03/12/2013 Authors: Kondo K; Bhushan S; King AL; Prabhu SD; Hamid T; Koenig S; Murohara T; Predmore BL; Gojon G; Gojon G
  • The summer of hydrogen sulfide: highlights from two international conferences.
    Med Gas Res Volume: 3 Page(s): 5
    02/25/2013 Authors: Calvert JW
  • Ablation of calcineurin A reveals hyperlipidemia and signaling cross-talks with phosphodiesterases.
    J Biol Chem Volume: 288 Page(s): 3477 - 3488
    02/01/2013 Authors: Suk HY; Zhou C; Yang TTC; Zhu H; Yu RYL; Olabisi O; Yang X; Brancho D; Kim J-Y; Scherer PE
  • Sodium Sulfide Therapy Attenuates Cardiac Dysfunction in the Setting of Heart Failure in a Nrf2-Dependent Manner
    CIRCULATION Volume: 126
    11/20/2012 Authors: Nicholson CK; Lambert JP; Alfonzo EML; Hansen JM; Calvert JW
  • Hydrogen Sulfide Therapy Induces Mitochondrial Biogenesis in the Setting of lschenmic-Induced Heart Failure
    CIRCULATION Volume: 126
    11/20/2012 Authors: Nicholson CK; Mo L; Corey C; Lefer DJ; Shiva S; Calvert JW
  • Sodium Sulfide Therapy Confers Cardioprotection in the Diabetic Heart by Activating AMP-Activated Protein Kinase
    CIRCULATION Volume: 126
    11/20/2012 Authors: Lambert JP; Nicholson CK; Amin H; Amin S; Calvert JW
  • Cardioprotective Role of NO Derived from Sodium Nitrite in Attenuating Severity of Chronic Ischemia-Induced Heart Failure
    CIRCULATION Volume: 126
    11/20/2012 Authors: Bhushan S; Kondo K; Zlatopolsky MA; Greer JJ; Calvert JW; Lefer DJ
  • Sodium sulfide therapy attenuates heart failure-induced ASK1 signaling in a thioredoxin-dependent manner
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY Volume: 27 Page(s): S42 - S42
    09/15/2012 Authors: Nicholson CK; Sadoshima J; Calvert JW
  • Sodium sulfide therapy attenuates myocardial ischemia-reperfusion injury in the type-2 diabetic heart via the activation of Nrf2 signaling
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY Volume: 27 Page(s): S28 - S28
    09/15/2012 Authors: Lambert J; Nicholson C; Calvert J
  • Thioredoxin-1 Is Essential for Hydrogen Sulfide-Mediated Cardioprotection in the Setting of Ischemic-Induced Heart Failure
    CIRCULATION RESEARCH Volume: 111
    08/03/2012 Authors: Nicholson CK; Moody BF; Hood RL; Sadoshima J; Calvert JW
  • Bax regulates primary necrosis through mitochondrial dynamics.
    Proc Natl Acad Sci U S A Volume: 109 Page(s): 6566 - 6571
    04/24/2012 Authors: Whelan RS; Konstantinidis K; Wei A-C; Chen Y; Reyna DE; Jha S; Yang Y; Calvert JW; Lindsten T; Thompson CB
  • Regulation and maintenance of vascular tone and patency in cardiovascular health and disease.
    Int J Vasc Med Volume: 2012 Page(s): 396369
    01/01/2012 Authors: Calvert JW; Kevil CG; Spite MR
  • Exercise to the rescue.
    J Physiol Volume: 589 Page(s): 5919 - 5920
    12/15/2011 Authors: Huffman DM; Calvert JW
  • Beta3-adrenoreceptor stimulation ameliorates myocardial ischemia-reperfusion injury via endothelial nitric oxide synthase and neuronal nitric oxide synthase activation.
    J Am Coll Cardiol Volume: 58 Page(s): 2683 - 2691
    12/13/2011 Authors: Aragn JP; Condit ME; Bhushan S; Predmore BL; Patel SS; Grinsfelder DB; Gundewar S; Jha S; Calvert JW; Barouch LA
  • Genetic Deletion of DJ-1/Park7 Increases Myocardial Ischemia/Reperfusion Injury
    CIRCULATION Volume: 124
    11/22/2011 Authors: Hood RL; Moody BF; Nicholson CK; Calvert JW
  • The Novel Hydrogen Sulfide Donor Diallyl Trisulfide Protects Against Ischemia-Reperfusion Injury by Inhibition of Mitochondrial Respiration
    CIRCULATION Volume: 124
    11/22/2011 Authors: Predmore B; Bhushan S; Aragon JP; Grinsfelder B; King A; Calvert J; Condit M; Lefer D
  • Inhibition of Calcineurin/NFAT Signaling During Exercise Training Protects the Heart Against Myocardial-Ischemia Reperfusion Injury
    CIRCULATION Volume: 124
    11/22/2011 Authors: Moody B; Hood RL; Nicholson CK; Lefer DJ; Calvert JW
  • Hydrogen Sulfide Preconditions the Diabetic Heart by Inactivating the Transcription Repressor Bach1 and Activating Nrf2 Signaling
    CIRCULATION Volume: 124
    11/22/2011 Authors: Moody BF; Nicholson CK; Hood RL; Calvert JW
  • Exercise protects against myocardial ischemia-reperfusion injury via stimulation of (3)-adrenergic receptors and increased nitric oxide signaling: role of nitrite and nitrosothiols.
    Circ Res Volume: 108 Page(s): 1448 - 1458
    06/10/2011 Authors: Calvert JW; Condit ME; Aragn JP; Nicholson CK; Moody BF; Hood RL; Sindler AL; Gundewar S; Seals DR; Barouch LA
  • Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging.
    Aging Cell Volume: 10 Page(s): 429 - 437
    06/01/2011 Authors: Sindler AL; Fleenor BS; Calvert JW; Marshall KD; Zigler ML; Lefer DJ; Seals DR
  • Nitrite supplementation reverses large elastic artery stiffening with aging: Potential role of arterial advanced glycation end-products
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY Volume: 24 Page(s): S27 - S27
    05/01/2011 Authors: Sindler AL; Marvi NK; Classen N; Calvert JW; Lefer DJ; Seals DR; Fleenor BS
  • Disruption of NEAT signaling impairs the cardioprotective effects of exercise training by reducing the nitrite reductase capacity of the heart
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY Volume: 24 Page(s): S24 - S25
    05/01/2011 Authors: Hood RL; Nicholson CK; Moody BF; Aragon JP; Lefer DJ; Calvert JW
  • Acute erythropoietin cardioprotection is mediated by endothelial response.
    Basic Res Cardiol Volume: 106 Page(s): 343 - 354
    05/01/2011 Authors: Teng R; Calvert JW; Sibmooh N; Piknova B; Suzuki N; Sun J; Martinez K; Yamamoto M; Schechter AN; Lefer DJ
  • Sodium nitrite therapy fails to attenuate the severity of ischemia-induced heart failure
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY Volume: 24 Page(s): S38 - S38
    05/01/2011 Authors: Bhushan S; Elston M; Aragon JP; Lavu M; Calvert JW; Predmore B; Kondo K; Lefer D
  • Stimulation of the beta 3-adrenergic receptor protects against myocardial ischemia-reperfusion injury by increasing cardiac nitrite levels
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY Volume: 24 Page(s): S23 - S23
    05/01/2011 Authors: Predmore B; Aragon JP; Patel S; Grinsfelder B; Gundewar S; Jha S; Elston M; Calvert J; Barouch L; Lavu M
  • Stimulation of beta(3)-adrenergic receptors during exercise protects the heart against ischemia-reperfusion injury by increasing the cardiac storage of nitrite and nitrosothiols
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY Volume: 24 Page(s): S23 - S23
    05/01/2011 Authors: Elston M; Aragon JP; Barouch L; Calvert J; Lefer D
  • Nitrite Supplementation improves age-associated vascular endothelial function and arterial markers of mitochondrial function
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY Volume: 24 Page(s): S40 - S40
    05/01/2011 Authors: Sindler AL; Howell KL; Zigler ML; LaRocca TJ; Fleenor BS; Calvert JW; Lefer DJ; Seals DR
  • Emergent role of gasotransmitters in ischemia-reperfusion injury.
    Med Gas Res Volume: 1 Page(s): 3
    04/27/2011 Authors: Moody BF; Calvert JW
  • Sodium nitrite treatment de-stiffens large elastic arteries in old mice: modulation of advanced glycation end-products
    FASEB JOURNAL Volume: 25
    04/01/2011 Authors: Fleenor BS; Sindler AL; Marvi NK; Claassen N; Calvert JW; Lefer DJ; Seals DR
  • Cardioprotective effects of nitrite during exercise.
    Cardiovasc Res Volume: 89 Page(s): 499 - 506
    02/15/2011 Authors: Calvert JW
  • Role of eNOS and nNOS in Beta3-Adrenergic Receptor Mediated Cardioprotection
    CIRCULATION Volume: 122
    11/23/2010 Authors: Aragon JP; Elston M; Grinsfelder DB; Lavu M; Calvert JW; Wright HM; Barouch LA; Lefer DJ
  • Inhibition of Calcineurin/NFAT Signaling Limits the Cardioprotective Effects of Exercise by Reducing the Nitrite Reductase Capacity of the Heart
    CIRCULATION Volume: 122
    11/23/2010 Authors: Nicholson CK; Aragon JP; Moody BF; Hood RL; Lefer DJ; Calvert JW
  • Hydrogen sulfide and ischemia-reperfusion injury.
    Pharmacol Res Volume: 62 Page(s): 289 - 297
    10/01/2010 Authors: Nicholson CK; Calvert JW
  • Acute humanin therapy attenuates myocardial ischemia and reperfusion injury in mice.
    Arterioscler Thromb Vasc Biol Volume: 30 Page(s): 1940 - 1948
    10/01/2010 Authors: Muzumdar RH; Huffman DM; Calvert JW; Jha S; Weinberg Y; Cui L; Nemkal A; Atzmon G; Klein L; Gundewar S
  • Evolutionarily conserved role of calcineurin in phosphodegron-dependent degradation of phosphodiesterase 4D.
    Mol Cell Biol Volume: 30 Page(s): 4379 - 4390
    09/01/2010 Authors: Zhu H; Suk HY; Yu RYL; Brancho D; Olabisi O; Yang TTC; Yang X; Zhang J; Moussaif M; Durand JL
  • Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice.
    Circulation Volume: 122 Page(s): 11 - 19
    07/27/2010 Authors: Calvert JW; Elston M; Nicholson CK; Gundewar S; Jha S; Elrod JW; Ramachandran A; Lefer DJ
  • Novel insights into hydrogen sulfide--mediated cytoprotection.
    Antioxid Redox Signal Volume: 12 Page(s): 1203 - 1217
    05/15/2010 Authors: Calvert JW; Coetzee WA; Lefer DJ
  • Nitrite supplementation reverses vascular endothelial dysfunction in old mice via improved nitric oxide bioavailability
    FASEB JOURNAL Volume: 24
    04/01/2010 Authors: Sindler AL; Calvert JW; Fleenor BS; Zigler ML; Lefer DJ; Seals DR
  • HYDROGEN SULFIDE THERAPY ATTENUATES ISCHEMIA-INDUCED HEART FAILURE VIA NRF2 AND NRF1 SIGNALING
    Volume: 55
    03/09/2010 Authors: Calvert JW; Elston M; Jha S; Gundewar S; Aragon JP; Grinsfelder DB; Ramachandran A; Elrod JW; Lefer DJ
  • HYDROGEN SULFIDE CONFERS CARDIOPROTECTION IN THE SETTING OF DIABETES
    Volume: 55
    03/09/2010 Authors: Calvert JW; Gundewar S; Elrod J; Lefer DJ
  • THE GENERATION AND STORAGE OF NITRIC OXIDE METABOLITES DURING EXERCISE TRAINING CONTRIBUTES TO EXERCISE-MEDIATED CARDIOPROTECTION
    Volume: 55
    03/09/2010 Authors: Calvert JW; Elston M; Sindler A; Gundewar S; Grinsfelder DB; Aragon JP; Seals DR; Lefer DJ
  • DOWNREGULATION OF CARDIAC MYOGLOBIN MAY LIMIT THE CARDIOPROTECTIVE EFFECTS OF NITRITE THERAPY FOLLOWING EXERCISE
    Volume: 55
    03/09/2010 Authors: Nicholson CK; Aragon JP; Grinsfelder DB; Elston M; Lefer DJ; Calvert JW
  • THE STABLE HYDROGEN SULFIDE DONOR, DIALLYL TRISULFIDE, PROTECTS AGAINST ACUTE MYOCARDIAL INFARCTION IN MICE
    Volume: 55
    03/09/2010 Authors: Predmore BL; Grinsfelder DB; Aragon JP; Elston M; Calvert JW; Lefer DJ
  • Clinical translation of nitrite therapy for cardiovascular diseases.
    Nitric Oxide Volume: 22 Page(s): 91 - 97
    02/15/2010 Authors: Calvert JW; Lefer DJ
  • The Transcription Factor Nrf2 is a Novel Target for the Treatment of Myocardial Ischemia-Reperfusion Injury
    CIRCULATION Volume: 120 Page(s): S1059 - S1059
    11/03/2009 Authors: Calvert JW; Grinsfelder DB; Elston M; Pattillo CB; Kevil CG; Lefer DJ
  • Humanin Analog Improves Myocardial Survival and Cardiac Function via Activation of AMPK and Regulation of Apoptosis
    CIRCULATION Volume: 120 Page(s): S836 - S837
    11/03/2009 Authors: Calvert J; Huffman D; Jha S; Weinberg Y; Gundewar S; Cui L; Li S; Nemkal A; Lefer D; Muzumdar R
  • Exogenous Erythropoietin Cardioprotection in a Mouse Ischemia/Reperfusion Injury Model Requires Nitric Oxide Synthase and Endothelial Cell Response
    CIRCULATION RESEARCH Volume: 105 Page(s): E52 - E52
    09/25/2009 Authors: Teng R; Calvert JW; Piknova B; Schechter AN; Lefer DJ; Noguchi CT
  • Hydrogen sulfide mediates cardioprotection through Nrf2 signaling.
    Circ Res Volume: 105 Page(s): 365 - 374
    08/14/2009 Authors: Calvert JW; Jha S; Gundewar S; Elrod JW; Ramachandran A; Pattillo CB; Kevil CG; Lefer DJ
  • Myocardial protection by nitrite.
    Cardiovasc Res Volume: 83 Page(s): 195 - 203
    07/15/2009 Authors: Calvert JW; Lefer DJ
  • Developmental programming resulting from maternal obesity in mice: effects on myocardial ischaemia-reperfusion injury.
    Exp Physiol Volume: 94 Page(s): 805 - 814
    07/01/2009 Authors: Calvert JW; Lefer DJ; Gundewar S; Poston L; Coetzee WA
  • Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure.
    Circ Res Volume: 104 Page(s): 403 - 411
    02/13/2009 Authors: Gundewar S; Calvert JW; Jha S; Toedt-Pingel I; Ji SY; Nunez D; Ramachandran A; Anaya-Cisneros M; Tian R; Lefer DJ
  • Metformin Improves Left Ventricular Function and Survival in Heart Failure Through AMPK-eNOS Activation
    CIRCULATION Volume: 118 Page(s): S356 - S356
    10/28/2008 Authors: Gundewar S; Calvert JW; Jha S; Tian R; Lefer DJ
  • Hydrogen Sulfide Therapy Attenuates Left Ventricular Dysfunction and Reduces Mortality In a Murine Model of Heart Failure
    CIRCULATION Volume: 118 Page(s): S441 - S441
    10/28/2008 Authors: Calvert JW; Gundewar S; Jha S; Elrod JW; Lefer DJ
  • Hydrogen Sulfide Mediates Myocardial Preconditioning via Upregulation of Antioxidant and Anti-Apoptotic Signaling Pathways
    CIRCULATION Volume: 118 Page(s): S354 - S354
    10/28/2008 Authors: Calvert JW; Jha S; Gundewar S; Duranski MR; Lefer DJ
  • Dietary nitrite restores NO homeostasis and is cardioprotective in endothelial nitric oxide synthase-deficient mice.
    Free Radic Biol Med Volume: 45 Page(s): 468 - 474
    08/15/2008 Authors: Bryan NS; Calvert JW; Gundewar S; Lefer DJ
  • Nitric oxide promotes distant organ protection: evidence for an endocrine role of nitric oxide.
    Proc Natl Acad Sci U S A Volume: 105 Page(s): 11430 - 11435
    08/12/2008 Authors: Elrod JW; Calvert JW; Gundewar S; Bryan NS; Lefer DJ
  • Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signaling.
    Am J Physiol Heart Circ Physiol Volume: 295 Page(s): H801 - H806
    08/01/2008 Authors: Jha S; Calvert JW; Duranski MR; Ramachandran A; Lefer DJ
  • Hydrogen sulfide (H2S) preconditions the myocardium against myocardial ischemia-reperfusion injury via up-regulation of anti-apoptotic signaling
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Volume: 51 Page(s): A189 - A189
    03/11/2008 Authors: Gundewar S; Jha S; Ji SY; Ramachandran A; Nunez DJ; Toedt-Pingel I; Patel S; Calvert JW; Elrod JW; Lefer DJ
  • Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling.
    Diabetes Volume: 57 Page(s): 696 - 705
    03/01/2008 Authors: Calvert JW; Gundewar S; Jha S; Greer JJM; Bestermann WH; Tian R; Lefer DJ
  • Thrombopoietin emerges as a new haematopoietic cytokine that confers cardioprotection against acute myocardial infarction.
    Cardiovasc Res Volume: 77 Page(s): 2 - 3
    01/01/2008 Authors: Calvert JW; Lefer DJ
  • Inhibition of c-Jun N-terminal kinase pathway attenuates cerebral vasospasm after experimental subarachnoid hemorrhage through the suppression of apoptosis.
    Acta Neurochir Suppl Volume: 104 Page(s): 27 - 31
    01/01/2008 Authors: Yatsushige H; Yamaguchi-Okada M; Zhou C; Calvert JW; Cahill J; Colohan ART; Zhang JH
  • Inhibition of N-ethylmaleimide-sensitive factor protects against myocardial ischemia/reperfusion injury.
    Circ Res Volume: 101 Page(s): 1247 - 1254
    12/07/2007 Authors: Calvert JW; Gundewar S; Yamakuchi M; Park PC; Baldwin WM; Lefer DJ; Lowenstein CJ
  • Dietary nitrite supplementation protects against myocardial ischemia-reperfusion injury.
    Proc Natl Acad Sci U S A Volume: 104 Page(s): 19144 - 19149
    11/27/2007 Authors: Bryan NS; Calvert JW; Elrod JW; Gundewar S; Ji SY; Lefer DJ
  • Dietary nitrite supplementation protects against myocardial ischemia-reperfusion injury by increasing myocardial nitric oxide stores
    CIRCULATION Volume: 116 Page(s): 165 - 165
    10/16/2007 Authors: Calvert JW; Bryan NS; Elrod JW; Elrod JW; Gundewar S; Lefer DJ
  • Acute metformin therapy confers cardioprotection via an AMPK-eNOS-dependent pathway
    CIRCULATION Volume: 116 Page(s): 257 - 257
    02/24/2011 Authors: Calvert JW; Gundewar S; Lefer DJ
  • Endogenous endocrine function of cardiac-derived nitric oxide yields distant organ protection against ischemic injury
    CIRCULATION Volume: 116 Page(s): 30 - 30
    10/16/2007 Authors: Elrod JW; Bryan NS; Calvert JW; Gundewar S; Lefer DJ
  • Cardionnyocyte overexpression of the hydrogen sulfide producing enzyme cystathioine gamma-lyase attenuates myocardial ischemia-reperfusion injury
    CIRCULATION Volume: 116 Page(s): 164 - 164
    10/16/2007 Authors: Elrod JW; Calvert JW; Chow C-W; Morrison J; Doeller JE; Kraus DW; Kimura H; Lefer DJ
  • Cytoprotective effects of N,N,N-trimethylsphingosine during ischemia- reperfusion injury are lost in the setting of obesity and diabetes.
    Am J Physiol Heart Circ Physiol Volume: 293 Page(s): H2462 - H2471
    10/01/2007 Authors: Gundewar S; Calvert JW; Elrod JW; Lefer DJ
  • Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function.
    Proc Natl Acad Sci U S A Volume: 104 Page(s): 15560 - 15565
    09/25/2007 Authors: Elrod JW; Calvert JW; Morrison J; Doeller JE; Kraus DW; Tao L; Jiao X; Scalia R; Kiss L; Szabo C
  • Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer.
    J Exp Med Volume: 204 Page(s): 2089 - 2102
    09/03/2007 Authors: Shiva S; Sack MN; Greer JJ; Duranski M; Ringwood LA; Burwell L; Wang X; MacArthur PH; Shoja A; Raghavachari N
  • Acute mettormin therapy protects against myocardial ischemia-reperfusion injury
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Volume: 49 Page(s): 222A - 222A
    03/06/2007 Authors: Calvert JW; Gundewar S; Koulogiannis KP; Holtzman D; Bartov DN; Jha S; Patel S; Lefer DJ
  • Hydrogen sulfide donor confers protection against acute myocardial ischemia-reperfusion injury
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Volume: 49 Page(s): 222A - 223A
    03/06/2007 Authors: Gundewar S; Calvert JW; Holtzman D; Koulogiannis KP; Bartov D; Jha S; Patel S; Elrod JW; Lefer DJ
  • Oxygen treatment restores energy status following experimental neonatal hypoxia-ischemia.
    Pediatr Crit Care Med Volume: 8 Page(s): 165 - 173
    03/01/2007 Authors: Calvert JW; Zhang JH
  • p53 may play an orchestrating role in apoptotic cell death after experimental subarachnoid hemorrhage.
    Neurosurgery Volume: 60 Page(s): 531 - 545
    03/01/2007 Authors: Cahill J; Calvert JW; Marcantonio S; Zhang JH
  • Hyperbaric oxygen and cerebral physiology.
    Neurol Res Volume: 29 Page(s): 132 - 141
    03/01/2007 Authors: Calvert JW; Cahill J; Zhang JH
  • The apoptosis inhibitor ARC undergoes ubiquitin-proteasomal-mediated degradation in response to death stimuli: identification of a degradation-resistant mutant.
    J Biol Chem Volume: 282 Page(s): 5522 - 5528
    02/23/2007 Authors: Nam Y-J; Mani K; Wu L; Peng C-F; Calvert JW; Foo RS-Y; Krishnamurthy B; Miao W; Ashton AW; Lefer DJ
  • Genetic overexpression of eNOS attenuates hepatic ischemia-reperfusion injury.
    Am J Physiol Heart Circ Physiol Volume: 291 Page(s): H2980 - H2986
    12/01/2006 Authors: Duranski MR; Elrod JW; Calvert JW; Bryan NS; Feelisch M; Lefer DJ
  • Limited role of inducible nitric oxide synthase in blood-brain barrier function after experimental subarachnoid hemorrhage.
    J Neurotrauma Volume: 23 Page(s): 1874 - 1882
    12/01/2006 Authors: Yatsushige H; Calvert JW; Cahill J; Zhang JH
  • Novel inhibitor of N-ethylmaleimide-sensitive factor protects against myocardial ischemia-reperfusion injury
    CIRCULATION RESEARCH Volume: 99 Page(s): 1282 - 1282
    11/24/2006 Authors: Calvert JW; Baldwin WM; Lefer DJ; Lowenstein CJ
  • Mechanisms of early brain injury after subarachnoid hemorrhage.
    J Cereb Blood Flow Metab Volume: 26 Page(s): 1341 - 1353
    11/01/2006 Authors: Cahill J; Calvert JW; Zhang JH
  • Statin therapy and myocardial no-reflow.
    Br J Pharmacol Volume: 149 Page(s): 229 - 231
    10/01/2006 Authors: Calvert JW; Lefer DJ
  • Neurovascular and neuronal protection by E64d after focal cerebral ischemia in rats.
    J Neurosci Res Volume: 84 Page(s): 832 - 840
    09/01/2006 Authors: Tsubokawa T; Yamaguchi-Okada M; Calvert JW; Solaroglu I; Shimamura N; Yata K; Zhang JH
  • Oxygen treatment after experimental hypoxia-ischemia in neonatal rats alters the expression of HIF-1alpha and its downstream target genes.
    J Appl Physiol (1985) Volume: 101 Page(s): 853 - 865
    09/01/2006 Authors: Calvert JW; Cahill J; Yamaguchi-Okada M; Zhang JH
  • Inhibition of integrin alphavbeta3 ameliorates focal cerebral ischemic damage in the rat middle cerebral artery occlusion model.
    Stroke Volume: 37 Page(s): 1902 - 1909
    07/01/2006 Authors: Shimamura N; Matchett G; Yatsushige H; Calvert JW; Ohkuma H; Zhang J
  • Vasospasm and p53-induced apoptosis in an experimental model of subarachnoid hemorrhage.
    Stroke Volume: 37 Page(s): 1868 - 1874
    07/01/2006 Authors: Cahill J; Calvert JW; Solaroglu I; Zhang JH
  • P53 plays a central role in apoptotic cell signaling in experimental subarachnoid hemorrhage and provides a potential therapeutic target
    STROKE Volume: 37 Page(s): 686 - 686
    02/01/2006 Authors: Cahill J; Calvert JW; Marcantonio S; Zhang JH
  • One-stage anterior approach for four-vessel occlusion in rat.
    Stroke Volume: 36 Page(s): 2212 - 2214
    10/01/2005 Authors: Yamaguchi M; Calvert JW; Kusaka G; Zhang JH
  • Technical note: preliminary results in development of a novel intracisternal penicillin seizure model in the rat.
    Front Biosci Volume: 10 Page(s): 3009 - 3012
    09/01/2005 Authors: Patwardhan RV; Calvert JW; Besio W; Kusaka G; Kusaka I; Zhang J; Nanda A
  • Electroconvulsive therapy for seizure control: preliminary data in a new seizure generation and control model.
    Front Biosci Volume: 10 Page(s): 3013 - 3019
    09/01/2005 Authors: Patwardhan RV; Besio W; Calvert JW; Kusaka G; Kusaka I; Zhang J; Nanda A
  • Neonatal hypoxia/ischemia is associated with decreased inflammatory mediators after erythropoietin administration.
    Stroke Volume: 36 Page(s): 1672 - 1678
    09/01/2010 Authors: Sun Y; Calvert JW; Zhang JH
  • Role of c-Jun N-terminal kinase in cerebral vasospasm after experimental subarachnoid hemorrhage.
    Stroke Volume: 36 Page(s): 1538 - 1543
    07/01/2005 Authors: Yatsushige H; Yamaguchi M; Zhou C; Calvert JW; Zhang JH
  • Pathophysiology of an hypoxic-ischemic insult during the perinatal period.
    Neurol Res Volume: 27 Page(s): 246 - 260
    04/01/2005 Authors: Calvert JW; Zhang JH
  • Hyperbaric oxygenation restores energy status following hypoxia-ischemia in a neonatal rat model
    FASEB JOURNAL Volume: 19 Page(s): A481 - A481
    03/04/2005 Authors: Calvert JW; Zhang JH
  • Multiple effects of hyperbaric oxygen on the expression of HIF-1 alpha and apoptotic genes in a global ischemia-hypotension rat model.
    Exp Neurol Volume: 191 Page(s): 198 - 210
    01/01/2005 Authors: Li Y; Zhou C; Calvert JW; Colohan ART; Zhang JH
  • Exposure of newborn rat pups to a single treatment of hyperoxia at normobaric and hyperbaric pressures attenuates brain damage and does not cause retinopathy of prematurity
    DEVELOPMENTAL NEUROSCIENCE Volume: 27 Page(s): 264 - 264
    01/01/2005 Authors: Calvert JW; Zhou C; Zhang JH
  • Neurovascular protection reduces early brain injury after subarachnoid hemorrhage.
    Stroke Volume: 35 Page(s): 2412 - 2417
    10/01/2004 Authors: Park S; Yamaguchi M; Zhou C; Calvert JW; Tang J; Zhang JH
  • Transient exposure of rat pups to hyperoxia at normobaric and hyperbaric pressures does not cause retinopathy of prematurity.
    Exp Neurol Volume: 189 Page(s): 150 - 161
    09/01/2004 Authors: Calvert JW; Zhou C; Zhang JH
  • New lumbar method for monitoring cerebrospinal fluid pressure in rats.
    J Neurosci Methods Volume: 135 Page(s): 121 - 127
    05/30/2004 Authors: Kusaka G; Calvert JW; Smelley C; Nanda A; Zhang JH
  • Effect of hyperbaric oxygen on apoptosis in neonatal hypoxia-ischemia rat model (vol 95, pg 2072, 2003)
    JOURNAL OF APPLIED PHYSIOLOGY Volume: 96 Page(s): 405 - 405
    01/01/2004 Authors: Calvert JW; Zhou CM; Nanda A; Zhang JH
  • Effect of hyperbaric oxygen on apoptosis in neonatal hypoxia-ischemia rat model.
    J Appl Physiol (1985) Volume: 95 Page(s): 2072 - 2080
    11/01/2003 Authors: Calvert JW; Zhou C; Nanda A; Zhang JH
  • Inhibition of apoptosis by hyperbaric oxygen in a rat focal cerebral ischemic model.
    J Cereb Blood Flow Metab Volume: 23 Page(s): 855 - 864
    07/01/2003 Authors: Yin D; Zhou C; Kusaka I; Calvert JW; Parent AD; Nanda A; Zhang JH
  • Inhibition of H-ras as a treatment for experimental brain C6 glioma.
    Brain Res Mol Brain Res Volume: 111 Page(s): 42 - 51
    03/17/2003 Authors: Perkins E; Calvert J; Lancon JA; Parent AD; Zhang J
  • A possible role of RhoA/Rho-kinase in experimental spinal cord injury in rat.
    Brain Res Volume: 959 Page(s): 29 - 38
    01/03/2003 Authors: Sung JK; Miao L; Calvert JW; Huang L; Louis Harkey H; Zhang JH
  • Hyperbaric oxygenation prevented brain injury induced by hypoxia-ischemia in a neonatal rat model.
    Brain Res Volume: 951 Page(s): 1 - 8
    09/27/2002 Authors: Calvert JW; Yin W; Patel M; Badr A; Mychaskiw G; Parent AD; Zhang JH
  • Hyperbaric oxygen as a treatment for neonatal hypoxia-ischemia
    DEVELOPMENTAL NEUROSCIENCE Volume: 24 Page(s): 463 - 464
    09/01/2002 Authors: Calvert JW; Nanda A; Zhang JH
  • Upregulation of small GTPase RhoA in the basilar artery from diabetic (mellitus) rats.
    Life Sci Volume: 71 Page(s): 1175 - 1185
    07/26/2002 Authors: Miao L; Calvert JW; Tang J; Zhang JH
  • Protective effect of hyperbaric oxygen on hypoxia-ischemia in neonatal rats
    STROKE Volume: 33 Page(s): 398 - 398
    01/01/2002 Authors: Zhang JH; Yin W; Badr A; Parent AD; Calvert JW
  • Age-related RhoA expression in blood vessels of rats.
    Mech Ageing Dev Volume: 122 Page(s): 1757 - 1770
    10/01/2001 Authors: Miao L; Calvert JW; Tang J; Parent AD; Zhang JH
  • Age-related RhoA expression in blood vessels of rats
    FASEB JOURNAL Volume: 15 Page(s): A124 - A124
    03/07/2001 Authors: Miao L; Calvert JW; Tang JP; Zhang JH
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