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Profile

Idelberto Badell

  • Department of Surgery
    Associate Professor
  • (404) 727-3927
  • ibadell@emory.edu
Head shot of Idelberto Badell

Overview

Dr. Badell received his MD from Baylor College of Medicine in 2006, after which he came to Emory for his general surgery residency and abdominal organ transplantation fellowship, which he completed in June 2015. Within this period of clinical training, he completed a pre-doctoral research fellowship in pathology at the University of Rochester School of Medicine and a post-doctoral research fellowship in transplant immunology at the Emory Transplant Center under the direction of Dr. Christian Larsen. During his clinical fellowship he re-engaged with the Emory Transplant Center's research enterprise and focused on basic immunology and clinical trial investigations. His clinical practice consists primarily of kidney/pancreas transplantation.

In 2017, Dr. Badell received an NIH K08 award to study the mechanisms of DSA formation following kidney transplantation DSA plays a significant role in the development of chronic rejection and fibrosis and can lead to late renal allograft loss. Dr. Badell believes that gaining a better understanding of the cellular interactions responsible for DSA formation after transplantation could guide the optimization of current immunosuppressive strategies and the development of novel therapies to control its production. Dr. Badell received Emory's 1% Award later in the year because the proposal obtained the highest possible score from the NIH study section.

The American Society of Transplant Surgeons (ASTS) awarded Dr. Badell its 2018 Vanguard Prize for authoring the previous year's best clinical and basic research manuscript from a young investigator. The paper was "Selective CD28 Blockade Results in Superior Inhibition of Donor-Specific T Follicular Helper Cell and Antibody Responses Relative to CTLA4-Ig," which was first published electronically in August 2017 by the American Journal of Transplantation. Later in 2018, the ASTS Foundation awarded him the Astellas Faculty Development Grant for his proposal, "Circulating T Follicular Helper Cells as a Biomarker for Donor-Specific Alloantibodies in Transplantation." Dr. Badell was selected as the American Journal of Transplantation Editors Pick in 2020 and 2021. In 2022, he received the American College of Surgeons Jacobson Promising Investigator Award.

Academic Appointment

  • Associate Professor of Surgery, Division of Transplantation, Department of Surgery, Emory University School of Medicine

Education

Degrees

  • MD from Baylor College of Medicine
  • BA in Bioschemistry from University of Texas at Austin

Research

Publications

  • Real-world registry evidence beware: Old-world risk analysis may not be applicable to new-world belatacept utilization.
    Am J Transplant
    04/19/2025 Authors: Badell IR
  • Identification of indirect CD4+ Tcell epitopes associated with transplant rejection provides a target for donor-specific tolerance induction.
    Immunity Volume: 58 Page(s): 448 - 464.e6
    02/11/2025 Authors: Zhanzak Z; Johnson AC; Foster P; Cardenas MA; Morris AB; Zhang J; Karadkhele G; Badell IR; Morris AA; Au-Yeung BB
  • Costimulatory Blockade and Solid Organ Transplantation: The Past, Present, and Future.
    Kidney Int Rep Volume: 8 Page(s): 2529 - 2545
    12/01/2023 Authors: Kitchens WH; Larsen CP; Badell IR
  • Implementation of an Online Intraoperative Assessment of Technical Performance for Surgical Trainees.
    J Surg Res Volume: 291 Page(s): 574 - 585
    11/01/2023 Authors: Faber DA; Hinman JM; Knauer EM; Hechenbleikner EM; Badell IR; Lin E; Srinivasan JK; Chahine AA; Papandria DJ
  • Memory T follicular helper cells drive donor-specific antibodies independent of memory B cells and primary germinal center and alloantibody formation.
    Am J Transplant Volume: 23 Page(s): 1511 - 1525
    10/01/2023 Authors: Zeng S; Crichton ES; Ford ML; Badell IR
  • Three-year Outcomes After Conversion From Monthly to Every 2-month Belatacept Maintenance Therapy in Kidney Transplant Recipients: Results From a Randomized Controlled Trial.
    Transplant Direct Volume: 9 Page(s): e1449
    03/01/2023 Authors: Johnson AC; Karadkhele GM; Shenvi N; Easley KA; Larsen CP; Badell IR
  • Impact of belatacept and tacrolimus on cytomegalovirus viral load control and relapse in moderate and high-risk cytomegalovirus serostatus kidney transplant recipients.
    Transpl Infect Dis Volume: 24 Page(s): e13983
    12/01/2022 Authors: Magua W; Johnson AC; Karadkhele GM; Badell IR; Vasanth P; Mehta AK; Easley KA; Newell KA; Rickert JB; Larsen CP
  • Indeterminate group A subtyping for prospective renal transplant donor.
    Transfusion Volume: 62 Page(s): 1927 - 1928
    09/01/2022 Authors: Achram R; Zerra PE; Delvadia B; Thompson L; Badell IR; Roback JD; Sullivan HC
  • Temporal trends and current use of de novo belatacept in kidney transplant recipients in the United States.
    Clin Transplant Volume: 36 Page(s): e14531
    03/01/2022 Authors: Karadkhele G; Duneton C; Garro R; Badell IR; Pearson TC; Larsen CP; Hogan J
  • CXCL13 Is an Indicator of Germinal Center Activity and Alloantibody Formation Following Transplantation.
    Transplant Direct Volume: 7 Page(s): e785
    12/01/2021 Authors: Crichton ES; Zeng S; La Muraglia GM; Badell IR
  • Belatacept in Kidney Transplant Recipients With Failed Allografts for the Prevention of Humoral Sensitization: A Pilot Randomized Controlled Trial.
    Transplantation Volume: 105 Page(s): e395 - e396
    12/01/2021 Authors: Badell IR; Bray RA; Elbein R; Chami AS; Easley KA; Pastan SO; Guasch A; Gebel HM; Adams AB; Larsen CP
  • Belatacept Conversion in Kidney After Liver Transplantation.
    Transplant Direct Volume: 7 Page(s): e780
    11/01/2021 Authors: Cristea O; Karadkhele G; Kitchens WH; Vasanth P; Larsen CP; Badell IR
  • Every 2-month belatacept maintenance therapy in kidney transplant recipients greater than 1-year posttransplant: A randomized, noninferiority trial.
    Am J Transplant Volume: 21 Page(s): 3066 - 3076
    09/01/2021 Authors: Badell IR; Parsons RF; Karadkhele G; Cristea O; Mead S; Thomas S; Robertson JM; Kim GS; Hanfelt JJ; Pastan SO
  • Alloreactive Memory T Follicular Helper Cells Rapidly Differentiate Into Effectors Independent of B Cell Memory Following Retransplantation
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 21 Page(s): 543 - 543
    06/01/2021 Authors: Zeng S; Crichton ES; Badell IR
  • The Absence of T Follicular Regulatory Cells Prolongs Germinal Center Reactivity in Transplantation
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 21 Page(s): 538 - 539
    06/01/2021 Authors: Crichton ES; Zeng S; Badell I
  • Superior inhibition of alloantibody responses with selective CD28 blockade is CTLA-4 dependent and T follicular helper cell specific.
    Am J Transplant Volume: 21 Page(s): 73 - 86
    01/01/2021 Authors: La Muraglia GM; Zeng S; Crichton ES; Wagener ME; Ford ML; Badell IR
  • CMV high-risk status and posttransplant outcomes in kidney transplant recipients treated with belatacept.
    Am J Transplant Volume: 21 Page(s): 208 - 221
    01/01/2021 Authors: Karadkhele G; Hogan J; Magua W; Zhang W; Badell IR; Mehta A; Lyon M; Pastan S; Pearson TC; Larsen CP
  • Belatacept Every Two Month Maintenance Dosing in Kidney Transplantation: A Randomized, Non-Inferiority Trial
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 20 Page(s): 445 - 445
    04/01/2020 Authors: Badell IR; Parsons R; Mead S; Thomas S; Karadkhele G; Pastan S; Larsen C
  • Belatacept Provides Superior Inhibition of Donor Specific Antibody Formation in Kidney Transplant Recipients with Acute Rejection
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 20 Page(s): 468 - 468
    04/01/2020 Authors: Cristea O; Larsen C; Badell I
  • Belatacept in Kidney Transplant Recipients with Previous Non-Renal Solid Organ Transplants
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 20 Page(s): 935 - 936
    04/01/2020 Authors: Cristea O; Larsen C; Badell I
  • T Follicular Regulatory Cell Deficiency Enhances Secondary T Follicular Helper Cell Responses after Transplantation
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 20 Page(s): 301 - 301
    04/01/2020 Authors: Crichton ES; Zeng S; Badell I
  • Serum CXCL13 Levels Indicate Humoral Alloreactivity and Donor Specific Antibody Formation
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 20 Page(s): 652 - 652
    04/01/2020 Authors: Crichton ES; Zeng S; Badell I
  • Opioid Utilization Post-Operatively in Kidney Transplantation
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 20 Page(s): 267 - 268
    04/01/2020 Authors: Gattis S; Badell R
  • The impact of belatacept on third-party HLA alloantibodies in highly sensitized kidney transplant recipients.
    Am J Transplant Volume: 20 Page(s): 573 - 581
    02/01/2020 Authors: Parsons RF; Zahid A; Bumb S; Decker H; Sullivan HC; Eun-Hyung Lee F; Badell IR; Ford ML; Larsen CP; Pearson TC
  • Circulating T follicular helper cells are a biomarker of humoral alloreactivity and predict donor-specific antibody formation after transplantation.
    Am J Transplant Volume: 20 Page(s): 75 - 87
    01/01/2020 Authors: La Muraglia GM; Wagener ME; Ford ML; Badell IR
  • De Novo Belatacept in a Kidney-After-Heart Transplant Recipient.
    Transplant Direct Volume: 6 Page(s): e515
    01/01/2020 Authors: Schenk AD; Anderson DJ; Cole RT; Badell IR; Larsen CP
  • Belatacept and CD28 Costimulation Blockade: Preventing and Reducing Alloantibodies over the Long Term.
    Curr Transplant Rep Volume: 6 Page(s): 277 - 284
    12/01/2019 Authors: Parsons RF; Larsen CP; Pearson TC; Badell IR
  • Abatacept as rescue immunosuppression after calcineurin inhibitor treatment failure in renal transplantation.
    Am J Transplant Volume: 19 Page(s): 2342 - 2349
    08/01/2019 Authors: Badell IR; Karadkhele GM; Vasanth P; Farris AB; Robertson JM; Larsen CP
  • Belatacept Monotherapy in Kidney Transplant Recipients with Failed Allografts Reduces Humoral Sensitization in a Single Center Randomized Controlled Trial.
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 19 Page(s): 450 - 450
    04/01/2019 Authors: Badell IR; Elbein R; Bray RA; Gebel HM; Adams AB; Larsen CP
  • Selective CD28 Blockade-Mediated Inhibition of T Follicular Helper Cell and DSA Responses is CTLA-4 Dependent.
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 19 Page(s): 565 - 565
    04/01/2019 Authors: La Muraglia GM; Ford ML; Badell IR
  • lCOS+PD-1+Circulating T Follicular Helper Cells Are a Biomarker of Humoral Alloreactisity and Predict Donor-Specific Antibody Generation Following Transplantation.
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 19 Page(s): 758 - 758
    04/01/2019 Authors: La Muraglia GM; Wagener ME; Ford ML; Badell IR
  • Memory T Follicular Helper Cell Alloresponse is Memory B Cell Independent and Inhibited by CD28 Costimulation Blockade.
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 19 Page(s): 566 - 567
    04/01/2019 Authors: Zeng S; La Muraglia GM; Ford ML; Badell IR
  • Abatacept as Rescue Immunosuppression after Calcineurin Inhibitor Treatment Failure in Renal Transplantation.
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 19 Page(s): 690 - 690
    04/01/2019 Authors: Badell IR; Vasanth P; Farris AB; Robertson JM; Karadkhele GM; Larsen CP
  • Microencapsulated adult porcine islets transplanted intraperitoneally in streptozotocin-diabetic non-human primates.
    Xenotransplantation Volume: 25 Page(s): e12450
    11/01/2018 Authors: Safley SA; Kenyon NS; Berman DM; Barber GF; Willman M; Duncanson S; Iwakoshi N; Holdcraft R; Gazda L; Thompson P
  • Circulating T Follicular Helper Cells Expand Following Transplantation and Exhibit a CD44(hi) Phenotype That Correlates with Peak Germinal Center Alloreactivity.
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 18 Page(s): 891 - 891
    06/01/2018 Authors: La Muraglia G; Wagener M; Ford M; Badell R
  • Selective CD28 blockade attenuates CTLA-4-dependent CD8+ memory T cell effector function and prolongs graft survival.
    JCI Insight Volume: 3
    01/11/2018 Authors: Liu D; Badell IR; Ford ML
  • Selective CD28 Blockade Results in Superior Inhibition of Donor-Specific T Follicular Helper Cell and Antibody Responses Relative to CTLA4-Ig.
    Am J Transplant Volume: 18 Page(s): 89 - 101
    01/01/2018 Authors: Badell IR; La Muraglia GM; Liu D; Wagener ME; Ding G; Ford ML
  • Single Donor-Derived Pseudomonas aeruginosa Pseudoaneurysms in Two Kidney Transplant Recipients: A Case Report of Dichotomous Allograft Outcomes.
    Transplant Proc Volume: 49 Page(s): 2357 - 2361
    12/01/2017 Authors: Berger MF; Badell IR
  • Mechanisms of destruction of microencapsulated adult porcine islets transplanted intraperitoneally in streptozotocin-diabetic non-human primates
    XENOTRANSPLANTATION Volume: 24
    09/01/2017 Authors: Safley S; Kenyon NM; Berman DM; Barber GF; Duncanson S; Iwakoshi N; Gordon KB; Holdcraft RW; Gazda LS; Badell IR
  • T-FR:T-FH Cell Ratio Correlates with Anti-Donor Germinal Center Reactivity and Donor-Specific Antibody Formation Following Transplantation
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 17 Page(s): 275 - 275
    04/01/2017 Authors: La Muraglia G; Ford M; Badell I
  • Inhibitory FcgRIIB Functionally Inhibits Donor-Reactive CD8(+) Memory T Cell Responses Following Transplantation
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 16 Page(s): 325 - 326
    06/01/2016 Authors: Pinelli D; Wagener M; Liu D; Badell I; Ford M
  • CTLA4 Negatively Regulates Donor-Reactive CXCR5+PD1+T Follicular Helper Cell Responses Following Transplantation
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 16 Page(s): 368 - 368
    06/01/2016 Authors: Badell I; Liu D; Suchard S; Nadler S; Ford M
  • T follicular helper cells in the generation of alloantibody and graft rejection.
    Curr Opin Organ Transplant Volume: 21 Page(s): 1 - 6
    02/01/2016 Authors: Badell IR; Ford ML
  • Pathogen Stimulation History Impacts Donor-Specific CD8(+) T Cell Susceptibility to Costimulation/Integrin Blockade-Based Therapy.
    Am J Transplant Volume: 15 Page(s): 3081 - 3094
    12/01/2015 Authors: Badell IR; Kitchens WH; Wagener ME; Lukacher AE; Larsen CP; Ford ML
  • Selective CD28 Blockade Exhibits Superior Suppression of Donor-Specific Antibody Relative to CTLA4Ig
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 14 Page(s): 36 - 36
    06/01/2014 Authors: Badell I; Liu D; Suchard S; Nadler S; Ford M
  • 2B4 (CD244) Induced By Selective CD28 Blockade Functionally Regulates Allograft-Specific CD8(+) T Cell Responses
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 14 Page(s): 322 - 322
    06/01/2014 Authors: Liu D; Krummey S; Badell I; Wagener M; Schneeweis L; Stetsko D; Suchard S; Nadler S; Ford M
  • 2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+ T cell responses.
    J Exp Med Volume: 211 Page(s): 297 - 311
    02/10/2014 Authors: Liu D; Krummey SM; Badell IR; Wagener M; Schneeweis LA; Stetsko DK; Suchard SJ; Nadler SG; Ford ML
  • Mechanisms of Allograft Tolerance
    Page(s): 119 - 133
    01/01/2014 Authors: Badell R; Kirk AD
  • Domino liver transplantation in maple syrup urine disease: a case report and review of the literature.
    Transplant Proc Volume: 45 Page(s): 806 - 809
    03/01/2013 Authors: Badell IR; Hanish SI; Hughes CB; Hewitt WR; Chung RT; Spivey JR; Knechtle SJ
  • Belatacept and sirolimus prolong nonhuman primate islet allograft survival: adverse consequences of concomitant alefacept therapy.
    Am J Transplant Volume: 13 Page(s): 312 - 319
    02/01/2013 Authors: Lowe MC; Badell IR; Turner AP; Thompson PW; Leopardi FV; Strobert EA; Larsen CP; Kirk AD
  • A novel monoclonal antibody to CD40 prolongs islet allograft survival.
    Am J Transplant Volume: 12 Page(s): 2079 - 2087
    08/01/2012 Authors: Lowe M; Badell IR; Thompson P; Martin B; Leopardi F; Strobert E; Price AA; Abdulkerim HS; Wang R; Iwakoshi NN
  • Alternative immunomodulatory strategies for xenotransplantation: CD40/154 pathway-sparing regimens promote xenograft survival.
    Am J Transplant Volume: 12 Page(s): 1765 - 1775
    07/01/2012 Authors: Thompson P; Badell IR; Lowe M; Turner A; Cano J; Avila J; Azimzadeh A; Cheng X; Pierson RN; Johnson B
  • CTLA4Ig prevents alloantibody formation following nonhuman primate islet transplantation using the CD40-specific antibody 3A8.
    Am J Transplant Volume: 12 Page(s): 1918 - 1923
    07/01/2012 Authors: Badell IR; Russell MC; Cardona K; Shaffer VO; Turner AP; Avila JG; Cano JA; Leopardi FV; Song M; Strobert EA
  • Belatacept and Sirolimus Prolong Islet Allograft Survival in Nonhuman Primates
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 12 Page(s): 479 - 479
    05/01/2012 Authors: Lowe MC; Badell IR; Turner A; Thompson P; Martin B; Leopardi F; Strobert E; Larsen CP; Kirk AD
  • A Novel Non-Depleting Monoclonal Antibody to CD40 Prolongs Islet Allograft Survival
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 12 Page(s): 35 - 35
    05/01/2012 Authors: Lowe MC; Badell IR; Thompson P; Martin B; Strobert E; Price AA; Abdulkerim HS; Wang R; Iwakoshi NN; Adams AB
  • Nondepleting anti-CD40-based therapy prolongs allograft survival in nonhuman primates.
    Am J Transplant Volume: 12 Page(s): 126 - 135
    01/01/2012 Authors: Badell IR; Thompson PW; Turner AP; Russell MC; Avila JG; Cano JA; Robertson JM; Leopardi FV; Strobert EA; Iwakoshi NN
  • Islet xenotransplantation using gal-deficient neonatal donors improves engraftment and function.
    Am J Transplant Volume: 11 Page(s): 2593 - 2602
    12/01/2011 Authors: Thompson P; Badell IR; Lowe M; Cano J; Song M; Leopardi F; Avila J; Ruhil R; Strobert E; Korbutt G
  • Function of microencapsulated adult porcine islet xenografts in streptozotocin-diabetic non-human primates
    XENOTRANSPLANTATION Volume: 18 Page(s): 277 - 277
    09/01/2011 Authors: Safley SA; Kenyon NS; Berman DM; Pileggi A; Kenyon N; Cui H; Badell I; Kirk AD; Holdcraft RW; Gazda L
  • CD40-specific costimulation blockade enhances neonatal porcine islet survival in nonhuman primates.
    Am J Transplant Volume: 11 Page(s): 947 - 957
    05/01/2011 Authors: Thompson P; Cardona K; Russell M; Badell IR; Shaffer V; Korbutt G; Rayat GR; Cano J; Song M; Jiang W
  • Clinically Applicable Immunosuppression with LFA3-Ig and Anti-LFA-1 Prolongs Xenoislet Survival
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 11 Page(s): 107 - 107
    04/01/2011 Authors: Thompson P; Badell I; Lowe M; Azimzadeh A; Cano J; Strobert E; Song M; Rajotte R; Larsen C; Kirk A
  • Islet Xenotransplantation Using Gal-Deficient Neonatal Porcine Donors Improves Engraftment and Function
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 11 Page(s): 80 - 80
    04/01/2011 Authors: Thompson P; Badell I; Lowe M; Cano J; Song M; Ruhil R; Strobert E; Iwakoshi N; Larsen C; Kirk A
  • LFA-1-specific therapy prolongs allograft survival in rhesus macaques.
    J Clin Invest Volume: 120 Page(s): 4520 - 4531
    12/01/2010 Authors: Badell IR; Russell MC; Thompson PW; Turner AP; Weaver TA; Robertson JM; Avila JG; Cano JA; Johnson BE; Song M
  • Experience with a novel efalizumab-based immunosuppressive regimen to facilitate single donor islet cell transplantation.
    Am J Transplant Volume: 10 Page(s): 2082 - 2091
    09/01/2010 Authors: Turgeon NA; Avila JG; Cano JA; Hutchinson JJ; Badell IR; Page AJ; Adams AB; Sears MH; Bowen PH; Kirk AD
  • In Vivo Characterization of a Novel Recombinant Anti-CD40 Monoclonal Antibody in Nonhuman Primates
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 10 Page(s): 214 - 214
    04/01/2010 Authors: Badell IR; Mendel JB; Robertson JM; Johnson BE; Wang X; Wang R; Iwakoshi NN; Reimann KA; Kirk AD; Larsen CP
  • Combination CD28/LFA-1 Blockade Promotes Islet Allograft Survival in Nonhuman Primates.
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 10 Page(s): 91 - 91
    04/01/2010 Authors: Badell IR; Thompson PW; Turner AP; Avila JG; Cano JA; Robertson JM; Leopardi FV; Johnson BE; Strobert EA; Kirk AD
  • Experience with a Novel Immunosuppressive Regimen To Facilitate Single Donor Islet Cell Transplantation Using Efalizumab
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 10 Page(s): 122 - 122
    04/01/2010 Authors: Turgeon NA; Cano JA; Hutchinson JJ; Badell IR; Page AJ; Kirk AD; Pearson TC; Larsen CP
  • A Novel Non-Depleting Anti-CD40 Antibody Prolongs Allogeneic Islet Survival in Nonhuman Primates.
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 10 Page(s): 146 - 146
    04/01/2010 Authors: Badell IR; Thompson PW; Turner AP; Avila JG; Cano JA; Robertson JM; Leopardi FV; Johnson BE; Strobert EA; Kirk AD
  • Towards a Translatable Regimen for Islet Xenotransplantation in Nonhuman Primates
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 10 Page(s): 187 - 187
    04/01/2010 Authors: Thompson PW; Badell IR; Turner AP; Avila J; Cano J; Strobert EA; Leopardi FV; Song M; Korbutt GS; Rayat GR
  • A novel calcineurin inhibitor- and sirolimus-free anti-LFA-1-based therapy enhances allogeneic islet survival and function in nonhuman primates
    JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS Volume: 209 Page(s): S56 - S56
    09/01/2009 Authors: Badell IR; Turner AP; Cano JA; Avila JG; Johnson BE; Leopardi FV; Swygert SG; Strobert EA; Kirk AD; Larsen CP
  • A novel calcineurin inhibitor- and sirolimus-free anti-LFA-1-based therapy enhances allogeneic islet survival and function in nonhuman primates
    XENOTRANSPLANTATION Volume: 16 Page(s): 314 - 314
    09/01/2009 Authors: Badell I; Turner A; Avila J; Cano J; Johnson B; Leopardi F; Swygert S; Strobert E; Kirk A; Larsen C
  • A Novel Anti-LFA-1-Based Therapy Enhances Allogeneic Islet Survival and Function in Nonhuman Primates.
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 9 Page(s): 367 - 367
    01/01/2009 Authors: Badell I; Russell M; Turner A; Avila J; Cano J; Johnson B; Strobert E; Kirk A; Larsen C
  • Time Profiles of Specific Physiologic and Genetic Parameters of Neonatal Porcine Pancreatic Islets.
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 9 Page(s): 469 - 469
    01/01/2009 Authors: Avila JG; Cano JA; Agarwal A; Iwakoshi N; Matar A; Russell MC; Turner A; Badell IR; Korbutt G; Rayat G
  • LFA-3-Ig (Alefacept) Prolongs Allograft Survival by Targeting Costimulation Blockade Resistant T Effector Memory Cells in Non-Human Primate Islet Transplantation.
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 9 Page(s): 237 - 237
    01/01/2009 Authors: Turner AP; Weaver T; Badell R; Cano J; Avila J; Turner P; Leopardi F; Strobert E; Larsen CP; Kirk AD
  • Selective Targeting of Antigen Experienced Memory T Cells with LFA3-IG: The Role of CD2 Cell Surface Density.
    AMERICAN JOURNAL OF TRANSPLANTATION Volume: 9 Page(s): 537 - 537
    01/01/2009 Authors: Weaver T; Charafeddine A; Turner A; Agarwal A; Russell M; Badell I; Stempora L; Larsen C; Kirk A
  • NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1.
    J Biol Chem Volume: 282 Page(s): 18245 - 18253
    06/22/2007 Authors: Yamashita T; Yao Z; Li F; Zhang Q; Badell IR; Schwarz EM; Takeshita S; Wagner EF; Noda M; Matsuo K
  • Tumor necrosis factor prevents alendronate-induced osteoclast apoptosis in vivo by stimulating Bcl-xL expression through Ets-2.
    Arthritis Rheum Volume: 52 Page(s): 2708 - 2718
    09/01/2005 Authors: Zhang Q; Badell IR; Schwarz EM; Boulukos KE; Yao Z; Boyce BF; Xing L
  • TNF-alpha and pathologic bone resorption.
    Keio J Med Volume: 54 Page(s): 127 - 131
    09/01/2005 Authors: Boyce BF; Li P; Yao Z; Zhang Q; Badell IR; Schwarz EM; O'Keefe RJ; Xing L
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