Haydn Kissick

Department of Urology
Assistant Professor

Overview

Dr. Haydn Kissick received his PhD degree in Microbiology and Immunology from the University of Western Australia (2011). He worked as a Senior Research Associate in the Departments of Urology as well as Microbiology and Immunology at Emory University School of Medicine (2016). He has significant training as a postdoctoral fellow as he focused on developing vaccines for prostate cancer using high throughput methods to identify novel epitopes. His research interests focus on tumor immunology, with special emphasis in prostate and genitourinary immunology. He will be working as faculty principal investigator, with focus on basic, translational, preclinical, and clinically correlative aspects of tumor immunology, immunotherapy and high-throughput genomic and epigenetic analyses pertaining to (but not limited to) prostate cancer and other genitourinary malignancies.

Academic Appointment

Assistant Professor, Secondary Appointment, Department of Microbiology and Immunology, Emory University School of Medicine
Assistant Professor, Primary Appointment, Department of Urology, Emory University School of Medicine

Education

Degrees

PhD from University of Western Australia, Perth

Research

Publications

Major histocompatibility complex and peptide specificity underpin CD8+ T cell direct alloresponse.
Am J Transplant Volume: 25 Page(s): 916 - 929
05/01/2025 Authors: Zhang W; Roversi FM; Morris AB; Ortiz K; Zhou G; Hadley A; Zhang X; Silva JAF; Breeden CP; Zhanzak Z
Combination radiation and PD-L1 enhance tumor control by stimulating CD8+PD-1+TCF-1+T cells in the tumor-draining lymph node.
Nat Commun Volume: 16 Page(s): 3522
04/14/2025 Authors: Shen Y; Connolly E; Aiello M; Zhou C; Chappa P; Song H; Tippitak P; Clark T; Cardenas M; Prokhnevska N
An early precursor CD8+ T cell that adapts to acute or chronic viral infection.
Nature Volume: 640 Page(s): 772 - 781
04/01/2025 Authors: McManus DT; Valanparambil RM; Medina CB; Scharer CD; McGuire DJ; Sobierajska E; Hu Y; Chang DY; Wieland A; Lee J
Neoadjuvant cabozantinib for locally advanced nonmetastatic clear cell renal cell carcinoma: a phase 2 trial.
Nat Cancer Volume: 6 Page(s): 432 - 444
03/01/2025 Authors: Bilen MA; Vo BT; Liu Y; Greenwald R; Davarpanah AH; McGuire D; Shiradkar R; Li L; Midya A; Nazha B
Identification of indirect CD4+ Tcell epitopes associated with transplant rejection provides a target for donor-specific tolerance induction.
Immunity Volume: 58 Page(s): 448 - 464.e6
02/11/2025 Authors: Zhanzak Z; Johnson AC; Foster P; Cardenas MA; Morris AB; Zhang J; Karadkhele G; Badell IR; Morris AA; Au-Yeung BB
Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis.
Sci Immunol Volume: 10 Page(s): eadl4909
01/10/2025 Authors: Elkins C; Ye C; Sivasami P; Mulpur R; Diaz-Saldana PP; Peng A; Xu M; Chiang Y-P; Moll S; Rivera-Rodriguez DE
Association of baseline inflammatory biomarkers and clinical outcomes in patients with advanced renal cell carcinoma treated with immune checkpoint inhibitors.
Volume: 17 Page(s): 17588359251316243
01/01/2025 Authors: Yildirim A; Wei M; Liu Y; Nazha B; Brown JT; Carthon BC; Choi Y; Suh L; Goswamy RV; McClintock GR
Differentiation fate of a stem-like CD4 T cell controls immunity to cancer.
Nature Volume: 636 Page(s): 224 - 232
12/01/2024 Authors: Cardenas MA; Prokhnevska N; Sobierajska E; Gregorova P; Medina CB; Valanparambil RM; Greenwald R; DelBalzo L; Bilen MA; Joshi SS
Author Correction: Differentiation fate of a stem-like CD4 T cell controls immunity to cancer.
Nature Volume: 635 Page(s): E9
11/01/2024 Authors: Cardenas MA; Prokhnevska N; Sobierajska E; Gregorova P; Medina CB; Valanparambil RM; Greenwald R; DelBalzo L; Bilen MA; Joshi SS
Pre-operative stereotactic radiosurgery and peri-operative dexamethasone for resectable brain metastases: a two-arm pilot study evaluating clinical outcomes and immunological correlates.
Nat Commun Volume: 15 Page(s): 8854
10/14/2024 Authors: Jansen CS; Pagadala MS; Cardenas MA; Prabhu RS; Goyal S; Zhou C; Chappa P; Vo BT; Ye C; Hopkins B
Neoadjuvant cabozantinib restores CD8+ T cells in patients with locally advanced non-metastatic clear cell renal cell carcinoma: a phase 2 trial.
Res Sq
08/08/2024 Authors: Bilen MA; Vo BT; Liu Y; Greenwald R; Davarpanah AH; McGuire D; Shiradkar R; Li L; Nazha B; Brown JT
Distinct SIV-specific CD8+ T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence.
Nat Immunol Volume: 25 Page(s): 1245 - 1256
07/01/2024 Authors: Strongin Z; Raymond Marchand L; Deleage C; Pampena MB; Cardenas MA; Beusch CM; Hoang TN; Urban EA; Gourves M; Nguyen K
Platinum-Based Chemotherapy Attenuates the Effector Response of CD8 T Cells to Concomitant PD-1 Blockade.
Clin Cancer Res Volume: 30 Page(s): 1833 - 1845
05/01/2024 Authors: Mariniello A; Nasti TH; Chang DY; Hashimoto M; Malik S; McManus DT; Lee J; McGuire DJ; Cardenas MA; Umana P
Impact of immunotherapy time-of-day infusion on survival and immunologic correlates in patients with metastatic renal cell carcinoma: a multicenter cohort analysis.
J Immunother Cancer Volume: 12
03/26/2024 Authors: Patel JS; Woo Y; Draper A; Jansen CS; Carlisle JW; Innominato PF; Lvi FA; Dhabaan L; Master VA; Bilen MA
Radiation and anti-PD-L1 synergize by stimulating a stem-like T cell population in the tumor-draining lymph node.
Res Sq
03/06/2024 Authors: Shen Y; Connolly E; Aiello M; Zhou C; Chappa P; Song H; Tippitak P; Clark T; Cardenas M; Prokhnevska N
Early generation of a precursor CD8 T cell that can adapt to acute or chronic viral infection.

02/12/2024 Authors: McManus DT; Valanparambil RM; Medina CB; Hu Y; Scharer CD; Sobierajska E; Chang DY; Wieland A; Lee J; Nasti TH
Localized high-risk prostate cancer harbors an androgen receptor low subpopulation susceptible to HER2 inhibition.
medRxiv
02/11/2024 Authors: Wilkinson S; Ku AT; Lis RT; King IM; Low D; Trostel SY; Bright JR; Terrigino NT; Baj A; Fenimore JM
CD28-CD57+ T cells from head and neck cancer patients produce high levels of cytotoxic granules and type II interferon but are not senescent.
Oncoimmunology Volume: 13 Page(s): 2367777
01/01/2024 Authors: Kinney BLC; Brammer B; Kansal V; Parrish CJ; Kissick HT; Liu Y; Saba NF; Buchwald ZS; El-Deiry MW; Patel MR
Characterisation of clinical response and transcriptional profiling of proliferating CD8 T cells in the blood of cancer patients after PD-1 monotherapy or combination therapy.
BMJ Oncol Volume: 3 Page(s): e000328
01/01/2024 Authors: Obeng RC; Nasti TH; Martens K; Li P; Mariniello A; Chang DY; Eberhardt CS; McGuire D; Kissick H; Daugherty C
Immune-Related Adverse Events and Clinical Outcomes in Advanced Urothelial Cancer Patients Treated With Immune Checkpoint Inhibitors.
Oncologist Volume: 28 Page(s): 1072 - 1078
12/11/2023 Authors: Sanda GE; Shabto JM; Goyal S; Liu Y; Martini DJ; Nazha B; Brown JT; Yantorni LB; Anne Russler G; Caulfield S
Characteristics and anatomic location of PD-1+TCF1+ stem-like CD8 T cells in chronic viral infection and cancer.
Proc Natl Acad Sci U S A Volume: 120 Page(s): e2221985120
10/10/2023 Authors: Im SJ; Obeng RC; Nasti TH; McManus D; Kamphorst AO; Gunisetty S; Prokhnevska N; Carlisle JW; Yu K; Sica GL
Precursor effector TCF1+CD39+Tox+CD8 T cells emerge in lymph node after SIV infection and are associated with better viral control
Volume: 52 Page(s): 306 - 306
10/01/2023 Authors: Strongin Z; Kissick HT; Hoang TN; Tharp GK; Nguyen K; Rahmberg AR; Brenchley JM; Deleage C; Bosinger SE; Paiardini M
Immune niches in brain metastases contain TCF1+ stem-like T cells, are associated with disease control and are modulated by preoperative SRS.
Res Sq
03/23/2023 Authors: Jansen CS; Prabhu RS; Pagadala MS; Chappa P; Goyal S; Zhou C; Neill SG; Prokhnevska N; Cardenas M; Hoang KB
Longitudinal Analysis of the Phenotype, Transcriptional Profile, and Anatomic Location of Memory CD8 T Cell Subsets after Acute Viral Infection.
J Virol Volume: 97 Page(s): e0155622
01/31/2023 Authors: Gill AL; Hudson WH; Valanparambil RM; Ahn E; McGuire DJ; Wieland A; McManus DT; Kissick HT; Akondy RS; Ahmed R
CD8+ Tcell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor.
Immunity Volume: 56 Page(s): 107 - 124.e5
01/10/2023 Authors: Prokhnevska N; Cardenas MA; Valanparambil RM; Sobierajska E; Barwick BG; Jansen C; Reyes Moon A; Gregorova P; delBalzo L; Greenwald R
Case Report: Exceptional response to nivolumab plus cabozantinib in a patient with extrarenal clear cell renal cell carcinoma.
Front Oncol Volume: 13 Page(s): 1271255
01/01/2023 Authors: Jansen CS; Choi Y; Evans ST; Greenwald R; Behnke JA; Hartman C; Kissick H; Harik LR; Bilen MA
Invariant NKT cell-augmented GM-CSF-secreting tumor vaccine is effective in advanced prostate cancer model.
Cancer Immunol Immunother Volume: 71 Page(s): 2943 - 2955
12/01/2022 Authors: Varghese B; Lynch L; Vriend LE; Draganov D; Clark JM; Kissick HT; Varghese S; Sanda MG; Dranoff G; Arredouani MS
Targeting vasoactive intestinal peptide-mediated signaling enhances response to immune checkpoint therapy in pancreatic ductal adenocarcinoma.
Nat Commun Volume: 13 Page(s): 6418
10/27/2022 Authors: Ravindranathan S; Passang T; Li J-M; Wang S; Dhamsania R; Ware MB; Zaidi MY; Zhu J; Cardenas M; Liu Y
TGF- regulates the stem-like state of PD-1+ TCF-1+ virus-specific CD8 T cells during chronic infection.
J Exp Med Volume: 219
10/03/2022 Authors: Hu Y; Hudson WH; Kissick HT; Medina CB; Baptista AP; Ma C; Liao W; Germain RN; Turley SJ; Zhang N
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells.
Nature Volume: 610 Page(s): 161 - 172
10/01/2022 Authors: Codarri Deak L; Nicolini V; Hashimoto M; Karagianni M; Schwalie PC; Lauener L; Varypataki EM; Richard M; Bommer E; Sam J
PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program.
Nature Volume: 610 Page(s): 173 - 181
10/01/2022 Authors: Hashimoto M; Araki K; Cardenas MA; Li P; Jadhav RR; Kissick HT; Hudson WH; McGuire DJ; Obeng RC; Wieland A
New epigenetic regulators of Tcell exhaustion.
Cancer Cell Volume: 40 Page(s): 708 - 710
07/11/2022 Authors: Kissick H; Ahmed R
Clinical outcome following checkpoint therapy in renal cell carcinoma is associated with a burst of activated CD8 T cells in blood.
J Immunother Cancer Volume: 10
07/01/2022 Authors: Carlisle JW; Jansen CS; Cardenas MA; Sobierajska E; Reyes AM; Greenwald R; Del Balzo L; Prokhnevska N; Kucuk O; Carthon BC
Sarcopenia and systemic inflammation are associated with decreased survival after cytoreductive nephrectomy for metastatic renal cell carcinoma.
Cancer Volume: 128 Page(s): 2073 - 2084
06/01/2022 Authors: Khan AI; Psutka SP; Patil DH; Hong G; Williams MA; Bilen MA; Sekhar A; Kissick HT; Narayan VM; Joshi SS
Defining the Molecular Hallmarks of T-Cell Memory.
Cold Spring Harb Perspect Biol Volume: 14
03/01/2022 Authors: Zebley CC; Akondy RS; Youngblood BA; Kissick HT
Body Composition as an Independent Predictive and Prognostic Biomarker in Advanced Urothelial Carcinoma Patients Treated with Immune Checkpoint Inhibitors.
Oncologist Volume: 26 Page(s): 1017 - 1025
12/01/2021 Authors: Martini DJ; Shabto JM; Goyal S; Liu Y; Olsen TA; Evans ST; Magod BL; Ravindranathan D; Brown JT; Yantorni L
Immunophenotyping and Transcriptional Profiling of Human Plasmablasts in Dengue.
J Virol Volume: 95 Page(s): e0061021
11/09/2021 Authors: Aggarwal C; Saini K; Reddy ES; Singla M; Nayak K; Chawla YM; Maheshwari D; Singh P; Sharma P; Bhatnagar P
TARGETING VASOACTIVE INTESTINAL PEPTIDE RECEPTOR SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA FOR ENHANCED ANTI-TUMOR RESPONSE TO CHECKPOINT BLOCKADE
Volume: 9 Page(s): A779 - A781
11/01/2021 Authors: Ravindranathan S; Fnu TP; Li JM; Dhamsania R; Ware M; Zaidi M; Wang S; Zhu J; Cardenas M; Liu Y
DISSECTING INTRATUMORAL IMMUNE ORGANIZATION: DEFINING THE COMPARATIVE CELLULAR COMPOSITION OF TERTIARY LYMPHOID STRUCTURES T-CELL SUPPORTIVE ANTIGEN PRESENTING NICHES IN RENAL TUMORS
Volume: 9 Page(s): A975 - A975
11/01/2021 Authors: Jansen C; Sobierajska E; Greenwald R; Carlisle J; Mullane P; Prokhnevska N; Cardenas M; Bilen M; Osunkoya A; Master V
CD8 T CELL ACTIVATION IN CANCER IS COMPRISED OF TWO DISTINCT PHASES
Volume: 9 Page(s): A686 - A686
11/01/2021 Authors: Prokhnevska N; Cardenas M; Valanparambil R; Sobierajska E; Jansen C; Master V; Sanda M; Kissick H
STEM-LIKE CD4 T CELLS IN CANCER
Volume: 9 Page(s): A669 - A669
11/01/2021 Authors: Cardenas M; Prokhnevska N; Jansen C; Master V; Kissick H
Immune-Related Adverse Events as Clinical Biomarkers in Patients with Metastatic Renal Cell Carcinoma Treated with Immune Checkpoint Inhibitors.
Oncologist Volume: 26 Page(s): e1742 - e1750
10/01/2021 Authors: Martini DJ; Goyal S; Liu Y; Evans ST; Olsen TA; Case K; Magod BL; Brown JT; Yantorni L; Russler GA
Functional HPV-specific PD-1+ stem-like CD8 T cells in head and neck cancer.
Nature Volume: 597 Page(s): 279 - 284
09/01/2021 Authors: Eberhardt CS; Kissick HT; Patel MR; Cardenas MA; Prokhnevska N; Obeng RC; Nasti TH; Griffith CC; Im SJ; Wang X
A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes.
Clin Cancer Res Volume: 27 Page(s): 4836 - 4847
09/01/2021 Authors: Calagua C; Ficial M; Jansen CS; Hirz T; Del Balzo L; Wilkinson S; Lake R; Ku AT; Voznesensky O; Sykes DB
Defining HPV-specific B cell responses in patients with head and neck cancer.
Nature Volume: 597 Page(s): 274 - 278
09/01/2021 Authors: Wieland A; Patel MR; Cardenas MA; Eberhardt CS; Hudson WH; Obeng RC; Griffith CC; Wang X; Chen ZG; Kissick HT
Vasoactive Intestinal Peptide Receptor Signaling: A Novel and Targetable Immune Checkpoint Pathway in Pancreatic Cancer
Volume: 50 Page(s): 1091 - 1092
08/01/2021 Authors: Ravindranathan S; Tenzin P; Ware M; Zaidi M; Wang S; Dhamsania R; Zhu J; Liu Y; Liu Y; Gumber S
Modified Glasgow Prognostic Score associated with survival in metastatic renal cell carcinoma treated with immune checkpoint inhibitors.
J Immunother Cancer Volume: 9
07/01/2021 Authors: Brown JT; Liu Y; Shabto JM; Martini D; Ravindranathan D; Hitron EE; Russler GA; Caulfield S; Yantorni L; Joshi SS
CD8 T cell differentiation in cancer is comprised of two distinct phases
Volume: 206
05/01/2021 Authors: Prokhnevska N; Cardenas M; Valanparambil R; Jansen C; Master V; Sanda M; Kissick H
Diminished monocyte response in severe COVID-19 patients
Volume: 206
05/01/2021 Authors: Davis-Gardner ME; Edara V; Lai L; Jin F; Floyd K; Nyhoff L; Mantus G; Adelman M; Pellegrini K; Chirkova T
Baseline Modified Glasgow Prognostic Score Associated with Survival in Metastatic Urothelial Carcinoma Treated with Immune Checkpoint Inhibitors.
Oncologist Volume: 26 Page(s): 397 - 405
05/01/2021 Authors: Brown JT; Liu Y; Shabto JM; Martini DJ; Ravindranathan D; Hitron EE; Russler GA; Caulfield S; Yantorni LB; Joshi SS
Transcriptional firing represses bactericidal activity in cystic fibrosis airway neutrophils.
Cell Rep Med Volume: 2 Page(s): 100239
04/20/2021 Authors: Margaroli C; Moncada-Giraldo D; Gulick DA; Dobosh B; Giacalone VD; Forrest OA; Sun F; Gu C; Gaggar A; Kissick H
An immunologic niche of antigen presenting cells and stem-like CD8+T-cells is present in non-small cell lung cancer brain metastases.
Volume: 27
04/01/2021 Authors: Jansen CS; del Balzo L; Prabhu R; Logan S; Chappa P; Patel K; Wilkinson S; Lake R; Shu H-KG; Zhong J
Case Report: Exceptional Response to Nivolumab Plus Ipilimumab in a Young Woman With TFE3-SFPQ Fusion Translocation-Associated Renal Cell Carcinoma.
Front Oncol Volume: 11 Page(s): 793808
01/01/2021 Authors: Martini DJ; Jansen CS; Harik LR; Evans ST; Olsen TA; Master VA; Kissick HT; Bilen MA
Body Composition Variables as Radiographic Biomarkers of Clinical Outcomes in Metastatic Renal Cell Carcinoma Patients Receiving Immune Checkpoint Inhibitors.
Front Oncol Volume: 11 Page(s): 707050
01/01/2021 Authors: Martini DJ; Olsen TA; Goyal S; Liu Y; Evans ST; Magod B; Brown JT; Yantorni L; Russler GA; Caulfield S
Organized immune cell interactions within tumors sustain a productive T-cell response.
Int Immunol Volume: 33 Page(s): 27 - 37
01/01/2021 Authors: Cardenas MA; Prokhnevska N; Kissick HT
CMV Status Drives Distinct Trajectories of CD4+ T Cell Differentiation.
Front Immunol Volume: 12 Page(s): 620386
01/01/2021 Authors: Zhang W; Morris AB; Peek EV; Karadkhele G; Robertson JM; Kissick HT; Larsen CP
Quality of CD8+ T cell immunity evoked in lymph nodes is compartmentalized by route of antigen transport and functional in tumor context.
Sci Adv Volume: 6
12/01/2020 Authors: O'Melia MJ; Rohner NA; Manspeaker MP; Francis DM; Kissick HT; Thomas SN
Sarcopenia and Neutrophil-Lymphocyte Ratio Are Associated with Overall Survival after Surgery for Localized Renal Cell Carcinoma
Volume: 231 Page(s): S339 - S339
10/01/2020 Authors: Higgins M; Nabavizadeh R; Patil DH; Ogan K; Kissick H; Bilen MA; Master V
Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy.
Sci Transl Med Volume: 12
09/30/2020 Authors: Francis DM; Manspeaker MP; Schudel A; Sestito LF; O'Melia MJ; Kissick HT; Pollack BP; Waller EK; Thomas SN
T Cell Receptor Diversity and Lineage Relationship between Virus-Specific CD8 T Cell Subsets during Chronic Lymphocytic Choriomeningitis Virus Infection.
J Virol Volume: 94
09/29/2020 Authors: Chang YM; Wieland A; Li Z-R; Im SJ; McGuire DJ; Kissick HT; Antia R; Ahmed R
Considerations for cancer immunotherapy biomarker research during COVID-19.
Endocr Relat Cancer Volume: 27 Page(s): C1 - C8
09/01/2020 Authors: Carlisle JW; Jansen CS; Bilen MA; Kissick H
Tumor-specific CD8 T cell activation in draining lymph nodes supports the anti-tumor CD8 T cell response
Volume: 204
05/01/2020 Authors: Prokhnevska N; Cardenas M; Jansen C; Valanparambil R; Master V; Sanda M; Kissick H
CD4 T cell phenotypes differentially modulate the CD8 T cell response in kidney cancer
Volume: 204
05/01/2020 Authors: Cardenas MA; Prokhnevska N; Jansen CS; Master VA; Kissick H
Transcriptional reprogramming drives neutrophil phenotype and function in chronic lung disease
Volume: 204
05/01/2020 Authors: Margaroli C; Giraldo DM; Arafat-Gulick D; Dobosh B; Giacalone V; Kissick H; Forrest OA; Gu C; Gibson G; Tirouvanziam RM
Novel risk group stratification for metastatic urothelial cancer patients treated with immune checkpoint inhibitors.
Cancer Med Volume: 9 Page(s): 2752 - 2760
04/01/2020 Authors: Shabto JM; Martini DJ; Liu Y; Ravindranathan D; Brown J; Hitron EE; Russler GA; Caulfield S; Kissick H; Alemozaffar M
Combined Effect of Sarcopenia and Systemic Inflammation on Survival in Patients with Advanced Stage Cancer Treated with Immunotherapy.
Oncologist Volume: 25 Page(s): e528 - e535
03/01/2020 Authors: Bilen MA; Martini DJ; Liu Y; Shabto JM; Brown JT; Williams M; Khan AI; Speak A; Lewis C; Collins H
Novel Risk Scoring System for Patients with Metastatic Renal Cell Carcinoma Treated with Immune Checkpoint Inhibitors.
Oncologist Volume: 25 Page(s): e484 - e491
03/01/2020 Authors: Martini DJ; Liu Y; Shabto JM; Carthon BC; Hitron EE; Russler GA; Caulfield S; Kissick HT; Harris WB; Kucuk O
Association of modified Glasgow Prognostic Score (mGPS) with survival outcomes in patients with metastatic renal cell carcinoma (mRCC) treated with immune checkpoint inhibitors (CPI)
Volume: 38
02/20/2020 Authors: Brown JT; Liu Y; Martini DJ; Shabto JM; Hitron E; Russler G; Caulfield S; Yantorni LB; Joshi SS; Kissick H
Association of baseline modified Glasgow Prognostic Score (mGPS) with survival outcomes in patients with metastatic urothelial cell carcinoma (mUCC) treated with immune checkpoint inhibitors (CPI)
Volume: 38
02/20/2020 Authors: Brown JT; Liu Y; Shabto JM; Martini DJ; Ravindranathan D; Hitron E; Russler G; Caulfield S; Yantorni LB; Joshi SS
CD45RB Status of CD8+ T Cell Memory Defines T Cell Receptor Affinity and Persistence.
Cell Rep Volume: 30 Page(s): 1282 - 1291.e5
02/04/2020 Authors: Krummey SM; Morris AB; Jacobs JR; McGuire DJ; Ando S; Tong KP; Zhang W; Robertson J; Guasch SA; Araki K
Adiposity may predict survival in patients with advanced stage cancer treated with immunotherapy in phase 1 clinical trials.
Cancer Volume: 126 Page(s): 575 - 582
02/01/2020 Authors: Martini DJ; Kline MR; Liu Y; Shabto JM; Williams MA; Khan AI; Lewis C; Collins H; Akce M; Kissick HT
The immunosuppressive phenotype of tumor-infiltrating neutrophils is associated with obesity in kidney cancer patients.
Oncoimmunology Volume: 9 Page(s): 1747731
01/01/2020 Authors: Margaroli C; Cardenas MA; Jansen CS; Moon Reyes A; Hosseinzadeh F; Hong G; Zhang Y; Kissick H; Tirouvanziam R; Master VA
Neoadjuvant Cabozantinib in an Unresectable Locally Advanced Renal Cell Carcinoma Patient Leads to Downsizing of Tumor Enabling Surgical Resection: A Case Report.
Front Oncol Volume: 10 Page(s): 622134
01/01/2020 Authors: Bilen MA; Jiang JF; Jansen CS; Brown JT; Harik LR; Sekhar A; Kissick H; Maithel SK; Kucuk O; Carthon B
Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection.
Immunity Volume: 51 Page(s): 1043 - 1058.e4
12/17/2019 Authors: Hudson WH; Gensheimer J; Hashimoto M; Wieland A; Valanparambil RM; Li P; Lin J-X; Konieczny BT; Im SJ; Freeman GJ
Novel Risk Scoring System for Patients with Metastatic Renal Cell Carcinoma Treated with Immune Checkpoint Inhibitors.
Oncologist
12/05/2019 Authors: Martini DJ; Liu Y; Shabto JM; Carthon BC; Hitron EE; Russler GA; Caulfield S; Kissick HT; Harris WB; Kucuk O
Combined Effect of Sarcopenia and Systemic Inflammation on Survival in Patients with Advanced Stage Cancer Treated with Immunotherapy.
Oncologist
12/05/2019 Authors: Bilen MA; Martini DJ; Liu Y; Shabto JM; Brown JT; Williams M; Khan AI; Speak A; Lewis C; Collins H
An intra-tumoral niche maintains and differentiates stem-like CD8 T cells.
Nature Volume: 576 Page(s): 465 - 470
12/01/2019 Authors: Jansen CS; Prokhnevska N; Master VA; Sanda MG; Carlisle JW; Bilen MA; Cardenas M; Wilkinson S; Lake R; Sowalsky AG
Phosphoinositide 3-Kinase Signaling Can Modulate MHC Class I and II Expression.
Mol Cancer Res Volume: 17 Page(s): 2395 - 2409
12/01/2019 Authors: Chandrasekaran S; Sasaki M; Scharer CD; Kissick HT; Patterson DG; Magliocca KR; Seykora JT; Sapkota B; Gutman DA; Cooper LA
Clinical outcomes of advanced stage cancer patients treated with sequential immunotherapy in phase 1 clinical trials.
Invest New Drugs Volume: 37 Page(s): 1198 - 1206
12/01/2019 Authors: Martini DJ; Liu Y; Shabto JM; Lewis C; Kline MR; Collins H; Akce M; Kissick HT; Carthon BC; Shaib WL
How tumor-specific CD8 T cell activation in draining lymph nodes supports the anti-tumor CD8 T cell response
Volume: 7
11/06/2019 Authors: Prokhnevska N; Valanparambil R; Jansen C; Master V; Sanda M; Kissick H
ACTIVE TRANSCRIPTIONAL MODULATION OF PATHOLOGICAL EXTRACELLULAR VESICLES BY HUMAN CF AIRWAY NEUTROPHILS
Volume: 54 Page(s): S156 - S156
10/01/2019 Authors: Margaroli C; Dobosh B; Giraldo MD; Arafat-Gulick D; Kissick H; Forrest OA; Sun F; Wu R; Gibson G; Tirouvanziam R
Sites of metastasis and association with clinical outcome in advanced stage cancer patients treated with immunotherapy.
BMC Cancer Volume: 19 Page(s): 857
08/29/2019 Authors: Bilen MA; Shabto JM; Martini DJ; Liu Y; Lewis C; Collins H; Akce M; Kissick H; Carthon BC; Shaib WL
Discovery of tetrahydroisoquinoline-containing CXCR4 antagonists with enhanced ADMET properties and evaluation as anti-cancer agents
Volume: 258
08/25/2019 Authors: Miller E; Jecs E; Sun C; Tahirovic Y; Sharma S; Wilson L; Kissick H; Huy N; Wilson R; Kim M
The requirement for immune infiltration and organization in the tumor microenvironment for successful immunotherapy in prostate cancer.
Urol Oncol Volume: 37 Page(s): 543 - 555
08/01/2019 Authors: Jansen CS; Prokhnevska N; Kissick HT
CD8 T-cell infiltration into renal tumors requires a supportive antigen-presenting niche
Volume: 79
07/01/2019 Authors: Jansen CS; Prokhnevska N; Master VA; Carlisle JW; Bilen MA; Reyes AM; Kissick HT
Reply to Tumor-associated macrophages: "Good cop-bad cop".
Cancer Volume: 125 Page(s): 1942 - 1943
06/01/2019 Authors: Bilen MA; Kissick HT; Harvey RD
Novel risk stratification criteria of metastatic renal cell carcinoma (mRCC) patients (pts) treated with immune checkpoint inhibitors (ICI).
Volume: 37
05/20/2019 Authors: Martini DJ; Liu Y; Shabto JM; Carthon BC; Russler G; Hitron E; Caulfield S; Kissick H; Harris W; Kucuk O
Inflammatory markers at baseline (C1) and cycle 3 (C3) and their association with clinical outcomes in urothelial cancer patients (pts) treated with immunotherapy (IO).
Volume: 37
03/01/2019 Authors: Shabto JM; Martini DJ; Liu Y; Ravindranathan D; Kline MR; Hitron E; Russler G; Caulfield S; Kissick H; Alemozaffar M
Association between immune-related adverse events (irAEs) and clinical outcomes (CO) in advanced urothelial cancer patients (pts) treated with immunotherapy (IO).
Volume: 37
03/01/2019 Authors: Shabto JM; Martini DJ; Liu Y; Ravindranathan D; Kline MR; Hitron E; Russler G; Caulfield S; Kissick H; Alemozaffar M
Sites of metastases (mets) and their association with clinical outcomes (CO) in urothelial cancer patients (pts) treated with immunotherapy (IO).
Volume: 37
03/01/2019 Authors: Shabto JM; Martini DJ; Liu Y; Ravindranathan D; Kline MR; Hitron E; Russler G; Caulfield S; Kissick H; Alemozaffar M
Programmed Death-Ligand 1 (PD-L1) Expression in Pheochromocytoma: Clinicopathologic Correlation
Volume: 99
03/01/2019 Authors: Xiong M-J; Kissick H; Master V; Osunkoya AO
Programmed Death-Ligand 1 (PD-L1) Expression in Pheochromocytoma: Clinicopathologic Correlation
Volume: 32
03/01/2019 Authors: Xiong M-J; Kissick H; Master V; Osunkoya AO
Systematic identification of markers and drug targets on exhausted CD8+T-cells
Volume: 7
02/01/2019 Authors: Hudson WH; Gensheimer JL; Kissick HT; Ahmed R
Sequential immunotherapy and association with clinical outcomes in advanced-stage cancer patients
Volume: 7
02/01/2019 Authors: Bilen M; Martini D; Liu Y; Lewis C; Collins H; Shabto J; Akce M; Kissick H; Carthon B; Shaib W
Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells.
Nat Commun Volume: 10 Page(s): 196
01/14/2019 Authors: Hudson WH; Prokhnevska N; Gensheimer J; Akondy R; McGuire DJ; Ahmed R; Kissick HT
Immunological Complexity of the Prostate Cancer Microenvironment Influences the Response to Immunotherapy.
Adv Exp Med Biol Volume: 1210 Page(s): 121 - 147
01/01/2019 Authors: Prokhnevska N; Emerson DA; Kissick HT; Redmond WL
The prognostic and predictive impact of inflammatory biomarkers in patients who have advanced-stage cancer treated with immunotherapy.
Cancer Volume: 125 Page(s): 127 - 134
01/01/2019 Authors: Bilen MA; Martini DJ; Liu Y; Lewis C; Collins HH; Shabto JM; Akce M; Kissick HT; Carthon BC; Shaib WL
Is It Possible to Develop Cancer Vaccines to Neoantigens, What Are the Major Challenges, and How Can These Be Overcome? Neoantigens as Vaccine Targets for Cancer.
Cold Spring Harb Perspect Biol Volume: 10
11/01/2018 Authors: Kissick HT
Sites of metastasis and association with clinical outcome (CO) in advanced stage cancer patients (pts) treated with immunotherapy (IO).
Ann Oncol Volume: 29 Suppl 8 Page(s): viii433
10/01/2018 Authors: Bilen MA; Shabto JM; Martini DJ; Liu Y; Lewis C; Collins HH; Akce M; Kissick H; Carthon BC; Shaib WL
Sarcopenia and inflammation predicts survival in advanced stage cancer patients (pts) treated with immunotherapy (IO).
Volume: 29 Suppl 8 Page(s): viii42
10/01/2018 Authors: Bilen MA; Martini DJ; Shabto JM; Liu Y; Khan AI; Williams MA; Lewis C; Collins HH; Kissick H; Carthon BC
TRANSCRIPTIONAL ADAPTATION IN NEUTROPHILS RECRUITED TO CYSTIC FIBROSIS AIRWAYS UNDERLIES CHANGES IN CANONICAL IMMUNE FUNCTIONS
Volume: 53 Page(s): 186 - 186
09/01/2018 Authors: Margaroli C; Arafat-Gulick D; Kissick H; Forrest OA; Sun F; Garimalla S; Wu R; Gibson G; Tirouvanziam R
Blood based biomarkers and association with clinical outcome (CO) in advanced stage patients (pts) treated with immunotherapy (IO)
Volume: 78
07/01/2018 Authors: Martini DJ; Liu Y; Lewis C; Collins H; Akce M; Kissick H; Carthon BC; Shaib WL; Alese OB; Pillai R
Association Between Pretreatment Neutrophil-to-Lymphocyte Ratio and Outcome of Patients With Metastatic Renal-Cell Carcinoma Treated With Nivolumab.
Clin Genitourin Cancer Volume: 16 Page(s): e563 - e575
06/01/2018 Authors: Bilen MA; Dutcher GMA; Liu Y; Ravindranathan D; Kissick HT; Carthon BC; Kucuk O; Harris WB; Master VA
Anti-PD1 (muDX 400) therapy given after radiation has greatest impact on (CD8+Tim3-CD73+) stem cell like cells: Implications for improved clinical trial design incorporating radiation and anti-PD1
Volume: 36
05/20/2018 Authors: Nasti T; Im S; Kissick H; Daugherty C; Lawson DH; Ahmed R; Khan MK
Early change in blood-based biomarkers and association with clinical outcome (CO) in advanced stage cancer patients (pts) treated with immunotherapy (IO)
Volume: 36
05/20/2018 Authors: Martini DJ; Liu Y; Lewis CM; Shabto JM; Akce M; Kissick H; Carthon BC; Shaib WL; Alese OB; Pillai RN
Immunologic profile and prognostic significance of tumor-infiltrating lymphocytes in renal cell carcinoma.
Volume: 36
02/20/2018 Authors: Khan AI; Jansen CS; Carlisle JW; Melnick KR; Kim KS; Hosseinzadeh F; Prokhnevska N; Bilen MA; Master VA; Kissick HT
Single center validation of neutrophil-to-lymphocyte ratio in localized and metastatic clear cell renal cell carcinoma.
Volume: 36
02/20/2018 Authors: Melnick KR; Patil DH; Khan AI; Kim FY; Torlak M; Bilen MA; Kucuk O; Carthon BC; Filson CP; Ogan K
Validation of a novel preoperative inflammatory score in localized, clear cell RCC.
Volume: 36
02/20/2018 Authors: Melnick KR; Patil DH; Khan AI; Kim FY; Bilen MA; Carthon BC; Kucuk O; Filson CP; Ogan K; Kissick HT
CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for Interventions.
Annu Rev Med Volume: 69 Page(s): 301 - 318
01/29/2018 Authors: Hashimoto M; Kamphorst AO; Im SJ; Kissick HT; Pillai RN; Ramalingam SS; Araki K; Ahmed R
Extracellular vesicles from bone marrow-derived mesenchymal stromal cells support ex vivo survival of human antibody secreting cells.
J Extracell Vesicles Volume: 7 Page(s): 1463778
01/01/2018 Authors: Nguyen DC; Lewis HC; Joyner C; Warren V; Xiao H; Kissick HT; Wu R; Galipeau J; Lee FE-H
Evaluation of programmed cell death protein 1 (PD-1) expression as a prognostic biomarker in patients with clear cell renal cell carcinoma.
Oncoimmunology Volume: 7 Page(s): e1413519
01/01/2018 Authors: Kim KS; Sekar RR; Patil D; Dimarco MA; Kissick HT; Bilen MA; Osunkoya AO; Master VA
Targeted Therapies: Immunologic Effects and Potential Applications Outside of Cancer.
J Clin Pharmacol Volume: 58 Page(s): 7 - 24
01/01/2018 Authors: Kersh AE; Ng S; Chang YM; Sasaki M; Thomas SN; Kissick HT; Lesinski GB; Kudchadkar RR; Waller EK; Pollack BP
Origin and differentiation of human memory CD8 T cells after vaccination.
Nature Volume: 552 Page(s): 362 - 367
12/21/2017 Authors: Akondy RS; Fitch M; Edupuganti S; Yang S; Kissick HT; Li KW; Youngblood BA; Abdelsamed HA; McGuire DJ; Cohen KW
Effector CD8 T cells dedifferentiate into long-lived memory cells.
Nature Volume: 552 Page(s): 404 - 409
12/21/2017 Authors: Youngblood B; Hale JS; Kissick HT; Ahn E; Xu X; Wieland A; Araki K; West EE; Ghoneim HE; Fan Y
MIGRATION INTO CF AIRWAY FLUID PROMOTES ADAPTIVE TRANSCRIPTIONAL REPROGRAMMING OF HUMAN NEUTROPHILS IN VIVO AND IN VITRO
Volume: 52 Page(s): S243 - S243
09/01/2017 Authors: Margaroli C; Arafat-Gulick D; Kissick H; Forrest OA; Garimalla S; Gibson G; Tirouvanziam R
Translation is actively regulated during the differentiation of CD8+ effector T cells.
Nat Immunol Volume: 18 Page(s): 1046 - 1057
09/01/2017 Authors: Araki K; Morita M; Bederman AG; Konieczny BT; Kissick HT; Sonenberg N; Ahmed R
Gleason Score 7 Prostate Cancers Emerge through Branched Evolution of Clonal Gleason Pattern 3 and 4.
Clin Cancer Res Volume: 23 Page(s): 3823 - 3833
07/15/2017 Authors: Sowalsky AG; Kissick HT; Gerrin SJ; Schaefer RJ; Xia Z; Russo JW; Arredouani MS; Bubley GJ; Sanda MG; Li W
An imprinted non-coding genomic cluster at 14q32 defines clinically relevant molecular subtypes in osteosarcoma across multiple independent datasets.
J Hematol Oncol Volume: 10 Page(s): 107
05/15/2017 Authors: Hill KE; Kelly AD; Kuijjer ML; Barry W; Rattani A; Garbutt CC; Kissick H; Janeway K; Perez-Atayde A; Goldsmith J
Correlation between inflammatory markers in blood and expression of costimulatory molecules on tumor-infiltrating CD8+lymphocytes in renal cell carcinoma.
Volume: 35
02/20/2017 Authors: Kissick HT; Kim KS; Chang YM; Master VA
Characterization of Human CD8 T Cell Responses in Dengue Virus-Infected Patients from India.
J Virol Volume: 90 Page(s): 11259 - 11278
12/15/2016 Authors: Chandele A; Sewatanon J; Gunisetty S; Singla M; Onlamoon N; Akondy RS; Kissick HT; Nayak K; Reddy ES; Kalam H
Application of small RNA sequencing to identify microRNAs in acute kidney injury and fibrosis.
Toxicol Appl Pharmacol Volume: 312 Page(s): 42 - 52
12/01/2016 Authors: Pellegrini KL; Gerlach CV; Craciun FL; Ramachandran K; Bijol V; Kissick HT; Vaidya VS
Long non-coding RNA expression during CD8(+) T cell differentiation and exhaustion
Volume: 4
11/01/2016 Authors: Hudson W; Kissick H; Hashimoto M; Ahmed R
Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination.
Nat Immunol Volume: 17 Page(s): 1226 - 1234
10/01/2016 Authors: Ellebedy AH; Jackson KJL; Kissick HT; Nakaya HI; Davis CW; Roskin KM; McElroy AK; Oshansky CM; Elbein R; Thomas S
Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy.
Nature Volume: 537 Page(s): 417 - 421
09/15/2016 Authors: Im SJ; Hashimoto M; Gerner MY; Lee J; Kissick HT; Burger MC; Shan Q; Hale JS; Lee J; Nasti TH
Major histocompatibility complex I upregulation in clear cell renal cell carcinoma is associated with increased survival.
Asian J Urol Volume: 3 Page(s): 75 - 81
04/01/2016 Authors: Sekar RR; De La Calle CM; Patil D; Holzman SA; Baum Y; Sheikh U; Huang JH; Osunkoya AO; Pollack BP; Kissick HT
EVALUATION OF TUMOR PD-1 EXPRESSION AS A PROGNOSTIC BIOMARKER IN PATIENTS WITH LOCALIZED CLEAR CELL RENAL CELL CARCINOMA
Volume: 195 Page(s): E1161 - E1162
04/01/2016 Authors: Kim K; Sekar R; DiMarco M; Petit D; Osunkoya A; Sica G; Kissick H; Pollack B; Master V
Understanding the Impact of ErbB Activating Events and Signal Transduction on Antigen Processing and Presentation: MHC Expression as a Model.
Front Pharmacol Volume: 7 Page(s): 327
01/01/2016 Authors: Kersh AE; Sasaki M; Cooper LA; Kissick HT; Pollack BP
Bone metastasis in prostate cancer: Recurring mitochondrial DNA mutation reveals selective pressure exerted by the bone microenvironment.
Bone Volume: 78 Page(s): 81 - 86
09/01/2015 Authors: Arnold RS; Fedewa SA; Goodman M; Osunkoya AO; Kissick HT; Morrissey C; True LD; Petros JA
The transcription factor ERG increases expression of neurotransmitter receptors on prostate cancer cells.
BMC Cancer Volume: 15 Page(s): 604
08/27/2015 Authors: Kissick HT; On ST; Dunn LK; Sanda MG; Asara JM; Pellegrini KL; Noel JK; Arredouani MS
The role of active vaccination in cancer immunotherapy: lessons from clinical trials.
Curr Opin Immunol Volume: 35 Page(s): 15 - 22
08/01/2015 Authors: Kissick HT; Sanda MG
Evaluation of major histocompatibility complex class I expression in clear cell renal cell carcinoma as a prognostic tool
Volume: 33
03/01/2015 Authors: de la Calle CM; Holzman SA; Sheikh U; Huang JH; Kissick HT; Osunkoya AO; Pollack BP; Patil D; Ogan K; Master VA
Beyond immune checkpoint blockade: new approaches to targeting host-tumor interactions in prostate cancer: report from the 2014 Coffey-Holden prostate cancer academy meeting.
Prostate Volume: 75 Page(s): 337 - 347
03/01/2015 Authors: Miyahira AK; Kissick HT; Bishop JL; Takeda DY; Barbieri CE; Simons JW; Pienta KJ; Soule HR
Successful combined intratumoral immunotherapy of established murine mesotheliomas requires B-cell involvement.
J Interferon Cytokine Res Volume: 35 Page(s): 100 - 107
02/01/2015 Authors: Krishnan S; Bakker E; Lee C; Kissick HT; Ireland DJ; Beilharz MW
Reinvigorating Exhausted T Cells by Blockade of the PD-1 Pathway.
For Immunopathol Dis Therap Volume: 6 Page(s): 7 - 17
01/01/2015 Authors: Lee J; Ahn E; Kissick HT; Ahmed R
High Expression of Major Histocompatibility Complex Class I in Clear Cell Renal Cell Carcinoma Is Associated with Improved Prognosis.
Urol Int Volume: 95 Page(s): 72 - 78
01/01/2015 Authors: Holzman SA; de la Calle CM; Kissick HT; Osunkoya AO; Pollack BP; Patil D; Ogan K; Master VA
Successful combined intra-tumoural immunotherapy of established murine mesotheliomas requires B cell involvement
Volume: 70 Page(s): 52 - 52
11/01/2014 Authors: Krishnan S; Bakker E; Lee C; Kissick HT; Ireland DJ; Beilharz MW
NAD+ protects against EAE by regulating CD4+ T-cell differentiation.
Nat Commun Volume: 5 Page(s): 5101
10/07/2014 Authors: Tullius SG; Biefer HRC; Li S; Trachtenberg AJ; Edtinger K; Quante M; Krenzien F; Uehara H; Yang X; Kissick HT
Androgens alter T-cell immunity by inhibiting T-helper 1 differentiation.
Proc Natl Acad Sci U S A Volume: 111 Page(s): 9887 - 9892
07/08/2014 Authors: Kissick HT; Sanda MG; Dunn LK; Pellegrini KL; On ST; Noel JK; Arredouani MS
The scavenger receptor MARCO modulates TLR-induced responses in dendritic cells.
PLoS One Volume: 9 Page(s): e104148
01/01/2014 Authors: Kissick HT; Dunn LK; Ghosh S; Nechama M; Kobzik L; Arredouani MS
Immunization with a peptide containing MHC class I and II epitopes derived from the tumor antigen SIM2 induces an effective CD4 and CD8 T-cell response.
PLoS One Volume: 9 Page(s): e93231
01/01/2014 Authors: Kissick HT; Sanda MG; Dunn LK; Arredouani MS
Development of a peptide-based vaccine targeting TMPRSS2:ERG fusion-positive prostate cancer.
Cancer Immunol Immunother Volume: 62 Page(s): 1831 - 1840
12/01/2013 Authors: Kissick HT; Sanda MG; Dunn LK; Arredouani MS
Androgens modulate anti-tumor immunity through interference with the T lymphocyte differentiation program
Volume: 190
05/01/2013 Authors: Arredouani MS; Kissick H; Dunn L; Sanda M
Tumour eradication and induction of memory against murine mesothelioma by combined immunotherapy.
Immunol Cell Biol Volume: 90 Page(s): 822 - 826
09/01/2012 Authors: Kissick HT; Ireland DJ; Krishnan S; Madondo M; Beilharz MW
The Role of Regulatory T Cells in Mesothelioma.
Cancer Microenviron Volume: 5 Page(s): 165 - 172
08/01/2012 Authors: Ireland DJ; Kissick HT; Beilharz MW
Topically applied Melaleuca alternifolia (tea tree) oil causes direct anti-cancer cytotoxicity in subcutaneous tumour bearing mice.
J Dermatol Sci Volume: 67 Page(s): 120 - 129
08/01/2012 Authors: Ireland DJ; Greay SJ; Hooper CM; Kissick HT; Filion P; Riley TV; Beilharz MW
Tumour eradication and induction of memory against murine mesothelioma by combined immunotherapy
Volume: 188
05/01/2012 Authors: Ireland D; Kissick H; Krishnan S; Madondo M; Beilharz M
Breaking immune tolerance to prostate-associated tumor antigens through Tim-1 receptor
Volume: 188
05/01/2012 Authors: Arredouani MS; Kissick H; Dunn L; Strom T; Sanda M
Immunogenic Peptides Derived from the Transcription Factor ERG as a Vaccine for Prostate Cancer
Volume: 188
05/01/2012 Authors: Kissick H; Dunn L; Lu B; Sanda M; Arredouani MS
Metabolic profiling of T-cell differentiation and tolerance
Volume: 188
05/01/2012 Authors: Kissick H; Finke J; Dunn L; Asara J; Sanda M; Arredouani MS
Distinct transcriptome of regulatory T cells in prostate cancer
Volume: 188
05/01/2012 Authors: Arredouani MS; Kissick H; Dunn L; Sanda M
A novel iNKT cell-mediated vaccine maneuver induces potent long-lasting anti-tumor immunity for advanced prostate cancer by boosting CD8+T cell memory and function
Volume: 188
05/01/2012 Authors: Varghese B; Lynch L; Vriend L; Kissick H; Dunn L; Varghese S; Dranoff G; Arredouani MS; Balk S; Exley M
A novel iNKT-mediated vaccine maneuver overcomes PD-1-mediated T cell exhaustion in cancer
Volume: 188
05/01/2012 Authors: Varghese B; Lynch L; Vriend L; Kissick H; Dunn L; Varghese S; Arredouani MS; Balk S; Exley M
Inhibition of established subcutaneous murine tumour growth with topical Melaleuca alternifolia (tea tree) oil.
Cancer Chemother Pharmacol Volume: 66 Page(s): 1095 - 1102
11/01/2010 Authors: Greay SJ; Ireland DJ; Kissick HT; Heenan PJ; Carson CF; Riley TV; Beilharz MW
Mechanisms of immune suppression exerted by regulatory T-cells in subcutaneous AE17 murine mesothelioma.
J Interferon Cytokine Res Volume: 30 Page(s): 829 - 834
11/01/2010 Authors: Kissick HT; Ireland DJ; Greay SJ; Beilharz MW
Induction of necrosis and cell cycle arrest in murine cancer cell lines by Melaleuca alternifolia (tea tree) oil and terpinen-4-ol.
Cancer Chemother Pharmacol Volume: 65 Page(s): 877 - 888
04/01/2010 Authors: Greay SJ; Ireland DJ; Kissick HT; Levy A; Beilharz MW; Riley TV; Carson CF
Combined intratumoral regulatory T-cell depletion and transforming growth factor- neutralization induces regression of established AE17 murine mesothelioma tumors.
J Interferon Cytokine Res Volume: 29 Page(s): 209 - 215
04/01/2009 Authors: Kissick HT; Ireland DJ; Beilharz MW
Pattern of regulatory T-cell migration in AE17 tumour bearing mice following tumour challenge
Volume: 43 Page(s): 322 - 323
09/01/2008 Authors: Kissick HT; Ireland DJ; Beilharz MW
Alpha-Tocopheryl succinate: toxicity and lack of anti-tumour activity in immuno-competent mice.
Food Chem Toxicol Volume: 46 Page(s): 508 - 512
02/01/2008 Authors: Ireland DJ; Kissick HT; Beilharz MW