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Profile

Hanjoong Jo PhD

  • Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory
    Professor
  • (404) 712-9654
  • hjo@emory.edu
  • Google Scholar publication
Head shot of Hanjoong Jo

Overview

Dr. Hanjoong Jo is John and Jan Portman Professor in the Coulter Department of Biomedical Engineering (BME) at Georgia Tech and Emory University, and Professor of Medicine at Emory University. He is also the Associate Chair of Emory in BME Department. Upon graduation from Korea University, Dr. Jo received PhD under the co-mentorship of Professors John Tarbell (Chemical Engineering) and Ted Hollis (Physiology) at Pennsylvania State University in 1989. Following postdoctoral training in Jay McDonald Lab at Washington University in St. Louis and University of Alabama at Birmingham, he became Assistant Professor in Pathology and BME. Dr. Jo joined the BME Department at Georgia Tech and Emory University in 2000. He directs the Cardiovascular Mechanobiology and Nanomedicine lab. His lab studies how mechanical force associated with blood flow regulates vascular biology and cardiovascular disease, especially atherosclerosis, aortic valve (AV) calcification, and abdominal aortic aneurysms. He has published more than 150 peer-reviewed papers and edited two books. He developed the mouse model of atherosclerosis, known as partial carotid ligation model, induced by disturbed flow. His work led to the discovery of several genes (mechanosensitive genes and microRNAs) and epigenetic controlling mechanisms that are regulated by bad blood flow and play key roles in atherosclerosis and AAA. By targeting some of these mechanosensitive genes, his lab has been able to treat atherosclerosis and AAA in mice. His lab is now working on nanotechnologies to developing targeted gene and drug therapies in an effort to translate mouse studies toward clinical application. He is an elected fellow of American Institute of Medical and Biological Engineering, Biomedical Engineering Society, American Heart Association and American Physiological Society. He serves as associate editors and editorial board members of several cardiovascular and biomedical engineering journals including Scientific Reports, Circulation Research, Atherosclerosis Thrombosis Vascular Biology, Am J Physiology, Cell Molecular Bioengineering and Cardiovascular Engineering and Technology. He also has been serving as reviewers and chairs of study sections of the NIH, NSF, Veterans Administration and Am Heart Association. He also organized several international meetings, and in 2012, he served as the Chair of the Annual BME Society Meeting. He is also the founding President of Korean-American BME Society and Chairs of US-Korea Annual BMES Workshops since 2013. He has been a Distinguished Visiting Professor at Ewha Womans University and Chonbuk National University.

Academic Appointment

  • Adjunct Professor, Department of Life Science, Ewha Womans University
  • Professor, Division of Cardiology, Department of Medicine, Emory University
  • Professor of Biomedical Engineering, Biomedical Engineering, Georgia Tech
  • Professor of Biomedical Engineering, Emory University
  • Member, Molecular and Systems Pharmacology Division, Emory University

Education

Degrees

  • BA from Korea University
  • PhD from Pennsylvania State University

Research

Focus

  • The major focus of my research is on understanding the biological and pathophysiologic responses of vascular endothelial cells to mechanical force caused by blood flow (shear stress). My research activities are directed toward understanding the molecular mechanisms by which disturbed blood flow regulates vascular endothelial biology and how it controls cardiovascular diseases atherosclerosis, aortic aneurysm and aortic valve diseases.

Publications

  • FAK activity exacerbates disturbed flow-mediated atherosclerosis via VEGFR2-CBL-NF-B signaling.
    J Biol Chem Page(s): 110383
    06/14/2025 Authors: Murphy JM; Kieu Tran DT; Jeong K; Nguyen L; Nguyen MT; Tambe D; Jo H; Erin Ahn E-Y; Steve Lim S-T
  • Lysyl-tRNA synthetase 1 promotes atherogenesis via autophagy-related secretion and inflammation.
    Sci Rep Volume: 15 Page(s): 11099
    04/01/2025 Authors: Yun K; Seo Y; Oh Y; Kim S; Maeng HS; Cho JG; Son YB; Son DJ; Kwon K; Kim S
  • Endothelial cell (EC)-specific Ctgf/Ccn2 expression increases EC reprogramming and atherosclerosis.
    Matrix Biol Volume: 136 Page(s): 102 - 110
    04/01/2025 Authors: Li F; Kumar S; Pokutta-Paskaleva A; Kang D-W; Kim C; Raykin J; Omojola V; Hoffmann C; Zhao F; Teichmann M
  • Disturbed Flow Induces Reprogramming of Endothelial Cells to Immune-like and Foam Cells under Hypercholesterolemia during Atherogenesis.

    03/07/2025 Authors: Park C; Baek KI; Hung R-C; Choi L; Jeong K; Kim P; Jahng AK; Kim JH; Meselhe M; Kannan A
  • Disturbed Flow Induces Reprogramming of Endothelial Cells to Immune-like and Foam Cells under Hypercholesterolemia during Atherogenesis.
    bioRxiv
    03/06/2025 Authors: Park C; Baek KI; Hung R-C; Choi L; Jeong K; Kim P; Jahng AK; Kim JH; Meselhe M; Kannan A
  • Inhibiting MiR-33a-3p Expression Fails to Enhance ApoAI-Mediated Cholesterol Efflux in Pro-Inflammatory Endothelial Cells.
    Medicina (Kaunas) Volume: 61
    02/13/2025 Authors: Huang K; Pokhrel A; Echesabal-Chen J; Scott J; Bruce T; Jo H; Stamatikos A
  • Endothelial IGFBP6 suppresses vascular inflammation and atherosclerosis.
    Nat Cardiovasc Res Volume: 4 Page(s): 145 - 162
    02/01/2025 Authors: Su M; Zhao W; Jiang H; Zhao Y; Liao Z; Liu Z; Xu M; Jiang S; Wu L; Yang Y
  • Side- and Disease-Dependent Changes in Human Aortic Valve Cell Population and Transcriptomic Heterogeneity Determined by Single-Cell RNA Sequencing.
    Genes (Basel) Volume: 15
    12/19/2024 Authors: Villa-Roel N; Park C; Andueza A; Baek KI; Su A; Blaser MC; Leshnower BG; Yoganathan A; Aikawa E; Jo H
  • FAK activity exacerbates disturbed flow-mediated atherosclerosis via VEGFR2-Cbl-NF-B signaling.
    bioRxiv
    12/08/2024 Authors: Murphy JM; Tran DTK; Jeong K; Nguyen L; Nguyen MT; Tambe D; Jo H; Ahn E-YE; Lim S-TS
  • Ultrasound frequency-controlled microbubble dynamics in brain vessels regulate the enrichment of inflammatory pathways in the blood-brain barrier.
    Nat Commun Volume: 15 Page(s): 8021
    09/13/2024 Authors: Guo Y; Lee H; Kim C; Park C; Yamamichi A; Chuntova P; Gallus M; Bernabeu MO; Okada H; Jo H
  • Saving KLF2/4 from -protocadherin to reduce vascular inflammation and atherosclerosis.
    Nat Cardiovasc Res Volume: 3 Page(s): 1021 - 1023
    09/01/2024 Authors: Park C; Baek KI; Jo H
  • A Biomimetic Leaflet Scaffold for Aortic Valve Remodeling.
    Adv Healthc Mater Volume: 13 Page(s): e2303972
    09/01/2024 Authors: De Jesus Morales KJ; Santosa U; Brazhkina O; Rajurkar P; Jo H; Davis ME
  • A renaissance of cerebral cavernous malformation proteins in vascular physiology.
    Nat Cardiovasc Res Volume: 3 Page(s): 771 - 773
    07/01/2024 Authors: Abdelilah-Seyfried S; Jo H
  • Publisher Correction: A renaissance of cerebral cavernous malformation proteins in vascular physiology.
    Nat Cardiovasc Res Volume: 3 Page(s): 884
    07/01/2024 Authors: Abdelilah-Seyfried S; Jo H
  • HEG1 Protects Against Atherosclerosis by Regulating Stable Flow-Induced KLF2/4 Expression in Endothelial Cells.
    Circulation Volume: 149 Page(s): 1183 - 1201
    04/09/2024 Authors: Tamargo IA; Baek KI; Xu C; Kang DW; Kim Y; Andueza A; Williams D; Demos C; Villa-Roel N; Kumar S
  • Atherosclerotic three-layer nanomatrix vascular sheets for high-throughput therapeutic evaluation.
    Biomaterials Volume: 305 Page(s): 122450
    03/01/2024 Authors: Chen J; Zhang X; Cross R; Ahn Y; Huskin G; Evans W; Hwang PT; Kim J-A; Brott BC; Jo H
  • Simulated microgravity improves maturation of cardiomyocytes derived from human induced pluripotent stem cells.
    Sci Rep Volume: 14 Page(s): 2243
    01/26/2024 Authors: Forghani P; Rashid A; Armand LC; Wolfson D; Liu R; Cho HC; Maxwell JT; Jo H; Salaita K; Xu C
  • EMID2 is a novel biotherapeutic for aggressive cancers identified by in vivo screening.
    J Exp Clin Cancer Res Volume: 43 Page(s): 15
    01/10/2024 Authors: Cappelletto A; Alf E; Volf N; Vu TVA; Bortolotti F; Ciucci G; Vodret S; Fantuz M; Perin M; Colliva A
  • Editorial: Single-cell OMICs analyses in cardiovascular diseases.
    Front Cardiovasc Med Volume: 11 Page(s): 1413184
    01/01/2024 Authors: Sonawane AR; Pucat M; Jo H
  • Hyperoxia impairs induced pluripotent stem cell-derived endothelial cells and drives an atherosclerosis-like transcriptional phenotype.
    JVS Vasc Sci Volume: 5 Page(s): 100193
    01/01/2024 Authors: Carr SM; Owsiany K; Scrivner O; McLaughlin D; Jo H; Brewster LP; Hekman KE
  • Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.
    Front Physiol Volume: 15 Page(s): 1327794
    01/01/2024 Authors: Tanaka LY; Kumar S; Gutierre LF; Magnun C; Kajihara D; Kang D-W; Laurindo FRM; Jo H
  • Blood flow patterns switch VEGFR2 activity through differential S-nitrosylation and S-oxidation.
    Cell Rep Volume: 42 Page(s): 113361
    11/28/2023 Authors: Kang DH; Kim Y; Min S; Lee SY; Chung KY; Baek I-J; Kwon K; Jo H; Kang SW
  • Nanodiscoidal Nucleic Acids for Gene Regulation.
    ACS Chem Biol Volume: 18 Page(s): 2349 - 2367
    11/17/2023 Authors: Sharma R; Narum S; Liu S; Dong Y; Baek KI; Jo H; Salaita K
  • Flow-inducedreprogramming of endothelial cells in atherosclerosis.
    Nat Rev Cardiol Volume: 20 Page(s): 738 - 753
    11/01/2023 Authors: Tamargo IA; Baek KI; Kim Y; Park C; Jo H
  • Endothelial CCRL2 induced by disturbed flow promotes atherosclerosis via chemerin-dependent 2 integrin activation in monocytes.
    Cardiovasc Res Volume: 119 Page(s): 1811 - 1824
    08/07/2023 Authors: Tang C; Chen G; Wu F; Cao Y; Yang F; You T; Liu C; Li M; Hu S; Ren L
  • Nuclear FAK in endothelium: An intrinsic inhibitor of NF-B activation in atherosclerosis.
    Atherosclerosis Volume: 379 Page(s): 117189
    08/01/2023 Authors: Murphy JM; Jeong K; Tran DTK; Cioffi DL; Campbell PM; Kim JH; Jo H; Ahn E-YE; Lim S-TS
  • Constructing Lipoparticles Capable of Endothelial Cell-Derived Exosome-Mediated Delivery of Anti-miR-33a-5p to Cultured Macrophages.
    Curr Issues Mol Biol Volume: 45 Page(s): 5631 - 5644
    07/04/2023 Authors: Echesabal-Chen J; Huang K; Vojtech L; Oladosu O; Esobi I; Sachdeva R; Vyavahare N; Jo H; Stamatikos A
  • Label-free atherosclerosis diagnosis through a blood drop of apolipoprotein E knockout mouse model using surface-enhanced Raman spectroscopy validated by machine learning algorithm.
    Bioeng Transl Med Volume: 8 Page(s): e10529
    07/01/2023 Authors: Lee S; Jue M; Cho M; Lee K; Paulson B; Jo H; Song JS; Kang S-J; Kim JK
  • The Impact of MiR-33a-5p Inhibition in Pro-Inflammatory Endothelial Cells.
    Diseases Volume: 11
    06/24/2023 Authors: Huang K; Pitman M; Oladosu O; Echesabal-Chen J; Vojtech L; Esobi I; Larsen J; Jo H; Stamatikos A
  • Arginine Dysregulation and Myocardial Dysfunction in a Mouse Model and Children with Chronic Kidney Disease.
    Nutrients Volume: 15
    04/30/2023 Authors: Reyes LZ; Winterberg PD; George RP; Kelleman M; Harris F; Jo H; Brown LAS; Morris CR
  • Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cells.
    Sci Rep Volume: 13 Page(s): 2404
    02/10/2023 Authors: Kim Y; Yu N; Jang YE; Lee E; Jung Y; Lee DJ; Taylor WR; Jo H; Kim J; Lee S
  • Myeloid CCN3 protects against aortic valve calcification.
    Cell Commun Signal Volume: 21 Page(s): 14
    01/20/2023 Authors: Tu P; Xu Q; Zhou X; Villa-Roel N; Kumar S; Dong N; Jo H; Ou C; Lin Z
  • Single-Cell RNA sequencing investigation of female-male differences under PAD conditions.
    Front Cardiovasc Med Volume: 10 Page(s): 1251141
    01/01/2023 Authors: Snchez Marrero G; Villa-Roel N; Li F; Park C; Kang D-W; Hekman KE; Jo H; Brewster LP
  • Endothelial Poldip2 regulates sepsis-induced lung injury via Rho pathway activation.
    Cardiovasc Res Volume: 118 Page(s): 2506 - 2518
    08/24/2022 Authors: Dolmatova EV; Forrester SJ; Wang K; Ou Z; Williams HC; Joseph G; Kumar S; Valdivia A; Kowalczyk AP; Qu H
  • Endothelial UCP2 Is a Mechanosensitive Suppressor of Atherosclerosis.
    Circ Res Volume: 131 Page(s): 424 - 441
    08/19/2022 Authors: Luo J-Y; Cheng CK; He L; Pu Y; Zhang Y; Lin X; Xu A; Lau CW; Tian XY; Ma RCW
  • Spatial control of robust transgene expression in mouse artery endothelium under ultrasound guidance.
    Signal Transduct Target Ther Volume: 7 Page(s): 225
    07/18/2022 Authors: Liu R; Qu S; Xu Y; Jo H; Dai Z
  • Hypoxia inducible factor 1 inhibitor PX-478 reduces atherosclerosis in mice.
    Atherosclerosis Volume: 344 Page(s): 20 - 30
    03/01/2022 Authors: Villa-Roel N; Ryu K; Gu L; Fernandez Esmerats J; Kang D-W; Kumar S; Jo H
  • Targeting mechanosensitive endothelial TXNDC5 to stabilize eNOS and reduce atherosclerosis in vivo.
    Sci Adv Volume: 8 Page(s): eabl8096
    01/21/2022 Authors: Yeh C-F; Cheng S-H; Lin Y-S; Shentu T-P; Huang R-T; Zhu J; Chen Y-T; Kumar S; Lin M-S; Kao H-L
  • Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis.
    Elife Volume: 11
    01/11/2022 Authors: Williams D; Mahmoud M; Liu R; Andueza A; Kumar S; Kang D-W; Zhang J; Tamargo I; Villa-Roel N; Baek K-I
  • Aging-regulated TUG1 is dispensable for endothelial cell function.
    PLoS One Volume: 17 Page(s): e0265160
    01/01/2022 Authors: Gimbel AT; Koziarek S; Theodorou K; Schulz JF; Stanicek L; Kremer V; Ali T; Gnther S; Kumar S; Jo H
  • Sox13 is a novel flow-sensitive transcription factor that prevents inflammation by repressing chemokine expression in endothelial cells.
    Front Cardiovasc Med Volume: 9 Page(s): 979745
    01/01/2022 Authors: Demos C; Johnson J; Andueza A; Park C; Kim Y; Villa-Roel N; Kang D-W; Kumar S; Jo H
  • HIF1A inhibitor PX-478 reduces pathological stretch-induced calcification and collagen turnover in aortic valve.
    Front Cardiovasc Med Volume: 9 Page(s): 1002067
    01/01/2022 Authors: Salim MT; Villa-Roel N; Vogel B; Jo H; Yoganathan AP
  • Conditional Antisense Oligonucleotides Triggered by miRNA.
    ACS Chem Biol Volume: 16 Page(s): 2255 - 2267
    11/19/2021 Authors: Zhang J; Sharma R; Ryu K; Shen P; Salaita K; Jo H
  • Isolation of Endothelial Cells from the Lumen of Mouse Carotid Arteries for Single-cell Multi-omics Experiments.
    J Vis Exp
    10/04/2021 Authors: Kumar S; Andueza A; Kim J; Kang D-W; Jo H
  • Very late vasomotor responses and gene expression with bioresorbable scaffolds and metallic drug-eluting stents.
    Catheter Cardiovasc Interv Volume: 98 Page(s): 723 - 732
    10/01/2021 Authors: Koh J-S; Gogas BD; Kumar S; Benham JJ; Sur S; Spilias N; Kumar A; Giddens DP; Rapoza R; Kereiakes DJ
  • Combined LXR and RXR Agonist Therapy Increases ABCA1 Protein Expression and Enhances ApoAI-Mediated Cholesterol Efflux in Cultured Endothelial Cells.
    Metabolites Volume: 11
    09/18/2021 Authors: Huang K; Jo H; Echesabal-Chen J; Stamatikos A
  • Delivery of Anti-microRNA-712 to Inflamed Endothelial Cells Using Poly(-amino ester) Nanoparticles Conjugated with VCAM-1 Targeting Peptide.
    Adv Healthc Mater Volume: 10 Page(s): e2001894
    08/01/2021 Authors: Dosta P; Tamargo I; Ramos V; Kumar S; Kang DW; Borrs S; Jo H
  • Mechanical forces regulate endothelial-to-mesenchymal transition and atherosclerosis via an Alk5-Shc mechanotransduction pathway.
    Sci Adv Volume: 7
    07/01/2021 Authors: Mehta V; Pang K-L; Givens CS; Chen Z; Huang J; Sweet DT; Jo H; Reader JS; Tzima E
  • Is Endothelial Dysfunction a Therapeutic Target for Peripheral Artery Disease?: PRDM16 is going out on a limb.
    Circ Res Volume: 129 Page(s): 78 - 80
    06/25/2021 Authors: Kumar S; Andueza A; Jo H
  • Focal Adhesion Kinase Activity and Localization is Critical for TNF--Induced Nuclear Factor-B Activation.
    Inflammation Volume: 44 Page(s): 1130 - 1144
    06/01/2021 Authors: Murphy JM; Jeong K; Cioffi DL; Campbell PM; Jo H; Ahn E-YE; Lim S-TS
  • Recent advances in nanomaterials for therapy and diagnosis for atherosclerosis.
    Adv Drug Deliv Rev Volume: 170 Page(s): 142 - 199
    03/01/2021 Authors: Chen J; Zhang X; Millican R; Sherwood J; Martin S; Jo H; Yoon Y-S; Brott BC; Jun H-W
  • Delivery of siRNA to Endothelial Cells In Vivo Using Lysine/Histidine Oligopeptide-Modified Poly(-amino ester) Nanoparticles.
    Cardiovasc Eng Technol Volume: 12 Page(s): 114 - 125
    02/01/2021 Authors: Dosta P; Demos C; Ramos V; Kang DW; Kumar S; Jo H; Borrs S
  • Special Issue on Professor John M. Tarbell's Contribution to Cardiovascular Engineering.
    Cardiovasc Eng Technol Volume: 12 Page(s): 1 - 8
    02/01/2021 Authors: Jo H; Manning K; Tarbell JM
  • Atorvastatin and blood flow regulate expression of distinctive sets of genes in mouse carotid artery endothelium.
    Volume: 87 Page(s): 97 - 130
    01/01/2021 Authors: Kumar S; Sur S; Perez J; Demos C; Kang D-W; Kim CW; Hu S; Xu K; Yang J; Jo H
  • Recent Progress in in vitro Models for Atherosclerosis Studies.
    Front Cardiovasc Med Volume: 8 Page(s): 790529
    01/01/2021 Authors: Chen J; Zhang X; Millican R; Lynd T; Gangasani M; Malhotra S; Sherwood J; Hwang PT; Cho Y; Brott BC
  • Characterization of Poldip2 knockout mice: Avoiding incorrect gene targeting.
    PLoS One Volume: 16 Page(s): e0247261
    01/01/2021 Authors: Lassgue B; Kumar S; Mandavilli R; Wang K; Tsai M; Kang D-W; Demos C; Hernandes MS; San Martn A; Taylor WR
  • Endothelial Reprogramming by Disturbed Flow Revealed by Single-Cell RNA and Chromatin Accessibility Study.
    Cell Rep Volume: 33 Page(s): 108491
    12/15/2020 Authors: Andueza A; Kumar S; Kim J; Kang D-W; Mumme HL; Perez JI; Villa-Roel N; Jo H
  • Stable Flow-Induced Expression of KLK10 Inhibits Endothelial Inflammation and Atherosclerosis
    Volume: 142
    11/17/2020 Authors: Williams D; Mahmoud M; Jo H
  • Deletion of NoxO1 limits atherosclerosis development in female mice.
    Redox Biol Volume: 37 Page(s): 101713
    10/01/2020 Authors: Buchmann GK; Schrmann C; Warwick T; Schulz MH; Spaeth M; Mller OJ; Schrder K; Jo H; Weissmann N; Brandes RP
  • Disturbed Flow Induces Atherosclerosis by Annexin A2-Mediated Integrin Activation.
    Circ Res Volume: 127 Page(s): 1091 - 1093
    09/25/2020 Authors: Demos C; Williams D; Jo H
  • Conditional Deoxyribozyme-Nanoparticle Conjugates for miRNA-Triggered Gene Regulation.
    ACS Appl Mater Interfaces Volume: 12 Page(s): 37851 - 37861
    08/26/2020 Authors: Zhang J; Ma R; Blanchard A; Petree J; Jo H; Salaita K
  • Targeted Intravenous Nanoparticle Delivery: Role of Flow and Endothelial Glycocalyx Integrity.
    Ann Biomed Eng Volume: 48 Page(s): 1941 - 1954
    07/01/2020 Authors: Cheng MJ; Mitra R; Okorafor CC; Nersesyan AA; Harding IC; Bal NN; Kumar R; Jo H; Sridhar S; Ebong EE
  • Affinity-Driven Design of Cargo-Switching Nanoparticles to Leverage a Cholesterol-Rich Microenvironment for Atherosclerosis Therapy.
    ACS Nano Volume: 14 Page(s): 6519 - 6531
    06/23/2020 Authors: Kim H; Kumar S; Kang D-W; Jo H; Park J-H
  • Pre-stiffened Arteries From Fibulin-5 Knockout Mice Have Accelerated Atherosclerosis After Partial Carotid Ligation
    Volume: 40
    05/01/2020 Authors: Li F; Kumar S; Jo H; Brewster LP
  • Correction for Glaser et al., The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition.
    Proc Natl Acad Sci U S A Volume: 117 Page(s): 8657
    04/14/2020
  • The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition.
    Proc Natl Acad Sci U S A Volume: 117 Page(s): 4180 - 4187
    02/25/2020 Authors: Glaser SF; Heumller AW; Tombor L; Hofmann P; Muhly-Reinholz M; Fischer A; Gnther S; Kokot KE; Hassel D; Kumar S
  • Disturbed Flow-induced Acetylation of Copper Chaperone Atox1 via Oxidative Inactivation of Sirt1 Promotes Inflammation and Atherosclerosis
    Volume: 140
    11/19/2019 Authors: Varadarajan S; Das A; Jo H; Abe J-I; Ushio-Fukai M; Fukai T
  • The novel coronary artery disease risk gene JCAD/KIAA1462 promotes endothelial dysfunction and atherosclerosis.
    Eur Heart J Volume: 40 Page(s): 2398 - 2408
    08/01/2019 Authors: Xu S; Xu Y; Liu P; Zhang S; Liu H; Slavin S; Kumar S; Koroleva M; Luo J; Wu X
  • The flagellin-TLR5-Nox4 axis promotes the migration of smooth muscle cells in atherosclerosis.
    Exp Mol Med Volume: 51 Page(s): 1 - 13
    07/10/2019 Authors: Kim J; Yoo J-Y; Suh JM; Park S; Kang D; Jo H; Bae YS
  • miR-214 is Stretch-Sensitive in Aortic Valve and Inhibits Aortic Valve Calcification.
    Ann Biomed Eng Volume: 47 Page(s): 1106 - 1115
    04/01/2019 Authors: Salim MT; Esmerats JF; Arjunon S; Villa-Roel N; Nerem RM; Jo H; Yoganathan AP
  • Disturbed Flow Increases UBE2C (Ubiquitin E2 Ligase C) via Loss of miR-483-3p, Inducing Aortic Valve Calcification by the pVHL (von Hippel-Lindau Protein) and HIF-1 (Hypoxia-Inducible Factor-1) Pathway in Endothelial Cells.
    Arterioscler Thromb Vasc Biol Volume: 39 Page(s): 467 - 481
    03/01/2019 Authors: Fernandez Esmerats J; Villa-Roel N; Kumar S; Gu L; Salim MT; Ohh M; Taylor WR; Nerem RM; Yoganathan AP; Jo H
  • Role of flow-sensitive microRNAs and long noncoding RNAs in vascular dysfunction and atherosclerosis.
    Vascul Pharmacol Volume: 114 Page(s): 76 - 92
    03/01/2019 Authors: Kumar S; Williams D; Sur S; Wang J-Y; Jo H
  • ZBTB46 is a shear-sensitive transcription factor inhibiting endothelial cell proliferation via gene expression regulation of cell cycle proteins.
    Lab Invest Volume: 99 Page(s): 305 - 318
    03/01/2019 Authors: Wang Y; Sun H-Y; Kumar S; Puerta MDM; Jo H; Rezvan A
  • Role of Noncoding RNAs in the Pathogenesis of Abdominal Aortic Aneurysm.
    Circ Res Volume: 124 Page(s): 619 - 630
    02/15/2019 Authors: Kumar S; Boon RA; Maegdefessel L; Dimmeler S; Jo H
  • Antioxidant-1 is a Mechanosensitive Cu-Dependent Transcription Factor Promoting Inflammation and Atherosclerosis.
    Volume: 138
    11/06/2018 Authors: Varadarajan S; Das A; Lizama KS; Abdelsaid K; He L; Leanhart S; Jo H; Abe J-I; Ushio-Fukai M; Fukai T
  • Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells.
    Nat Commun Volume: 9 Page(s): 2292
    06/12/2018 Authors: Hitzel J; Lee E; Zhang Y; Bibli SI; Li X; Zukunft S; Pflger B; Hu J; Schrmann C; Vasconez AE
  • Mechanosensitive microRNA-181b Regulates Aortic Valve Endothelial Matrix Degradation by Targeting TIMP3.
    Cardiovasc Eng Technol Volume: 9 Page(s): 141 - 150
    06/01/2018 Authors: Heath JM; Fernandez Esmerats J; Khambouneheuang L; Kumar S; Simmons R; Jo H
  • Editorial: Special Issue on Heart Valve Mechanobiology : New Insights into Mechanical Regulation of Valve Disease and Regeneration.
    Cardiovasc Eng Technol Volume: 9 Page(s): 121 - 125
    06/01/2018 Authors: Simmons CA; Jo H
  • Correction to: Editorial: Special Issue on Heart Valve Mechanobiology : New Insights into Mechanical Regulation of Valve Disease and Regeneration.
    Cardiovasc Eng Technol Volume: 9 Page(s): 268
    06/01/2018 Authors: Simmons CA; Jo H
  • Vascular Semaphorin 7A Upregulation by Disturbed Flow Promotes Atherosclerosis Through Endothelial 1 Integrin.
    Arterioscler Thromb Vasc Biol Volume: 38 Page(s): 335 - 343
    02/01/2018 Authors: Hu S; Liu Y; You T; Heath J; Xu L; Zheng X; Wang A; Wang Y; Li F; Yang F
  • 3D Imaging and Quantitative Analysis of Vascular Networks: A Comparison of Ultramicroscopy and Micro-Computed Tomography.
    Theranostics Volume: 8 Page(s): 2117 - 2133
    01/01/2018 Authors: Epah J; Plfi K; Dienst FL; Malacarne PF; Bremer R; Salamon M; Kumar S; Jo H; Schrmann C; Brandes RP
  • Altered Amygdala Resting-State Functional Connectivity and Hemispheric Asymmetry in Patients With Social Anxiety Disorder.
    Front Psychiatry Volume: 9 Page(s): 164
    01/01/2018 Authors: Jung Y-H; Shin JE; Lee YI; Jang JH; Jo HJ; Choi S-H
  • Conserved Gene Microsynteny Unveils Functional Interaction Between Protein Disulfide Isomerase and Rho Guanine-Dissociation Inhibitor Families.
    Sci Rep Volume: 7 Page(s): 17262
    12/08/2017 Authors: Moretti AIS; Pavanelli JC; Nolasco P; Leisegang MS; Tanaka LY; Fernandes CG; Wosniak J; Kajihara D; Dias MH; Fernandes DC
  • JMJD2B is Involved in the Epigenetic Regulation During Endothelial to Mesenchymal Transition
    Volume: 136
    11/14/2017 Authors: Glaser S-F; Boeckel J-N; John D; Muhly-Reinholz M; Fischer A; Doering C; Cremer S; Kumar S; Jo H; Boon R
  • Accelerated Atherosclerosis Development in C57BL6 Mice by Overexpressing Adeno-associated Virus-mediated Gain-of-function Mutant of Proprotein Convertase Subtilisin/kexin Type 9 Gene and Partial Carotid Ligation
    Volume: 136
    11/14/2017 Authors: Kumar S; Kang DW; Rezvan A; Jo H
  • Mechanical Activation of Hypoxia-Inducible Factor 1 Drives Endothelial Dysfunction at Atheroprone Sites.
    Arterioscler Thromb Vasc Biol Volume: 37 Page(s): 2087 - 2101
    11/01/2017 Authors: Feng S; Bowden N; Fragiadaki M; Souilhol C; Hsiao S; Mahmoud M; Allen S; Pirri D; Ayllon BT; Akhtar S
  • Reduced Suicidality and Enhanced Neuronal Integrity With High Frequency Repetitive Transcranial Magnetic Stimulation Treatment in Adolescents
    Volume: 42 Page(s): S355 - S356
    11/01/2017 Authors: Croarkin P; Lewis C; Jo HJ; Camsari DD; Voort JV; Schak K; Port J
  • Disturbed Flow Promotes Arterial Stiffening Through Thrombospondin-1.
    Circulation Volume: 136 Page(s): 1217 - 1232
    09/26/2017 Authors: Kim CW; Pokutta-Paskaleva A; Kumar S; Timmins LH; Morris AD; Kang D-W; Dalal S; Chadid T; Kuo KM; Raykin J
  • Accelerated atherosclerosis development in C57Bl6 mice by overexpressing AAV-mediated PCSK9 and partial carotid ligation.
    Lab Invest Volume: 97 Page(s): 935 - 945
    08/01/2017 Authors: Kumar S; Kang D-W; Rezvan A; Jo H
  • Functional screening of mammalian mechanosensitive genes using Drosophila RNAi library-Smarcd3/Bap60 is a mechanosensitive pro-inflammatory gene
    Volume: 31
    04/01/2017 Authors: Kumar S; Jo H
  • KLF2 and KLF4 control endothelial identity and vascular integrity.
    JCI Insight Volume: 2 Page(s): e91700
    02/23/2017 Authors: Sangwung P; Zhou G; Nayak L; Chan ER; Kumar S; Kang D-W; Zhang R; Liao X; Lu Y; Sugi K
  • A Large-Scale, Functional Screening of Mammalian Mechanosensitive Genes Using Drosophila Rnai library-Smarcd3/Bap60 is a Mechanosensitive Pro-Inflammatory Gene
    Volume: 134
    11/11/2016 Authors: Kumar S; Jang IH; Kang DW; Kim C; Lee WJ; Jo H
  • Antioxidant-1, Proinflammatory Cu-Dependent Transcription Factor, Mediates Disturbed Flow-Induced Endothelial Cell Inflammation and Atherosclerosis
    Volume: 134
    11/11/2016 Authors: Varadarajan S; Das A; Kato A; Lizama KS; Waghulkar A; Surenkhuu B; Jo H; Ushio-Fukai M; Fukai T
  • Shear-Dependent Aortic Valve Endothelial Inflammation and Calcification Are Regulated by O-GlcNAc Modification of MEF2C Transcription Factor
    Volume: 134
    11/11/2016 Authors: Heath J; Kim H; Esmerats JF; Simmons R; Kumar S; Cho J; Jo H
  • Functional screening of mammalian mechanosensitive genes using Drosophila RNAi library- Smarcd3/Bap60 is a mechanosensitive pro-inflammatory gene.
    Sci Rep Volume: 6 Page(s): 36461
    11/07/2016 Authors: Kumar S; Jang I-H; Kim CW; Kang D-W; Lee WJ; Jo H
  • Very Late Vasomotor Responses and Gene Expression Profiles of Porcine Coronary Arteries at 4 Years after Deployment of the Everolimus-eluting Bioresorbable Vascular Scaffold and the Everolimus-eluting Metallic Xience V stent
    Volume: 68 Page(s): B334 - B335
    11/01/2016 Authors: Gogas BD; Kumar S; Benham J; Panchal D; Bouchi Y; Hung O; Gandhi R; Spilias N; Singhal E; Giddens DP
  • TCT-828 Very Late Vasomotor Responses and Gene Expression Profiles of Porcine Coronary Arteries at 4 Years after Deployment of the Everolimus-eluting Bioresorbable Vascular Scaffold and the Everolimus-eluting Metallic Xience V stent.
    J Am Coll Cardiol Volume: 68 Page(s): B334 - B335
    11/01/2016 Authors: Gogas BD; Kumar S; Benham J; Panchal D; Bouchi Y; Hung O; Gandhi R; Spilias N; Singhal E; Giddens DP
  • Deep transcriptomic profiling reveals the similarity between endothelial cells cultured under static and oscillatory shear stress conditions.
    Physiol Genomics Volume: 48 Page(s): 660 - 666
    09/01/2016 Authors: Qiao C; Meng F; Jang I; Jo H; Chen YE; Zhang J
  • Omics-based approaches to understand mechanosensitive endothelial biology and atherosclerosis.
    Wiley Interdiscip Rev Syst Biol Med Volume: 8 Page(s): 378 - 401
    09/01/2016 Authors: Simmons RD; Kumar S; Thabet SR; Sur S; Jo H
  • Shear-Sensitive Genes in Aortic Valve Endothelium.
    Antioxid Redox Signal Volume: 25 Page(s): 401 - 414
    09/01/2016 Authors: Fernndez Esmerats J; Heath J; Jo H
  • Simulated Microgravity and 3D Culture Enhance Induction, Viability, Proliferation and Differentiation of Cardiac Progenitors from Human Pluripotent Stem Cells.
    Sci Rep Volume: 6 Page(s): 30956
    08/05/2016 Authors: Jha R; Wu Q; Singh M; Preininger MK; Han P; Ding G; Cho HC; Jo H; Maher KO; Wagner MB
  • Discovery of novel peptides targeting pro-atherogenic endothelium in disturbed flow regions -Targeted siRNA delivery to pro-atherogenic endothelium in vivo.
    Sci Rep Volume: 6 Page(s): 25636
    05/12/2016 Authors: Chung J; Shim H; Kim K; Lee D; Kim WJ; Kang DH; Kang SW; Jo H; Kwon K
  • Identification of side- and shear-dependent microRNAs regulating porcine aortic valve pathogenesis.
    Sci Rep Volume: 6 Page(s): 25397
    05/06/2016 Authors: Rathan S; Ankeny CJ; Arjunon S; Ferdous Z; Kumar S; Fernandez Esmerats J; Heath JM; Nerem RM; Yoganathan AP; Jo H
  • Alternative Macrophages Promote Atherosclerosis Progression by Increasing Intraplaque Angiogenesis and Vascular Permeability via HIF-1 alpha/VEGF-A-dependent Pathway
    Volume: 36
    05/01/2016 Authors: Guo L; Akahori H; Polavarapu R; Harari E; Karmali V; King AL; Choi CU; Cheng Q; Jo H; Thabet S
  • ALTERNATIVE MACROPHAGES PROMOTE INTRAPLAQUE ANGIOGENESIS AND VASCULAR PERMEABILITY IN HUMAN ATHEROSCLEROSIS
    Volume: 67 Page(s): 2241 - 2241
    04/05/2016 Authors: Finn AV; Akahori H; Guo L; Polavarapu R; Karmali V; King A; Choi C; Cheng Q; Jo H; Thabet S
  • High glucose and palmitate increases bone morphogenic protein 4 expression in human endothelial cells.
    Korean J Physiol Pharmacol Volume: 20 Page(s): 169 - 175
    03/01/2016 Authors: Hong O-K; Yoo S-J; Son J-W; Kim M-K; Baek K-H; Song K-H; Cha B-Y; Jo H; Kwon H-S
  • The role of endothelial mechanosensitive genes in atherosclerosis and omics approaches.
    Arch Biochem Biophys Volume: 591 Page(s): 111 - 131
    02/01/2016 Authors: Simmons RD; Kumar S; Jo H
  • Shear-Sensitive miRNA-181b Impairs Anti-Inflammatory Signaling in the Aortic Valve Endothelium
    Volume: 134 Page(s): 167 - 167
    01/01/2016 Authors: Heath J; Esmerats JF; Simmons R; Kumar S; Jo H
  • Role of miRNA-483-3p in Valvular Endothelial Dysfunction
    Volume: 134 Page(s): 178 - 178
    01/01/2016 Authors: Esmerats JF; Heath J; Kumar S; Jo H
  • The NADPH oxidase Nox4 has anti-atherosclerotic functions.
    Eur Heart J Volume: 36 Page(s): 3447 - 3456
    12/21/2015 Authors: Schrmann C; Rezende F; Kruse C; Yasar Y; Lwe O; Fork C; van de Sluis B; Bremer R; Weissmann N; Shah AM
  • The role of epigenetics in the endothelial cell shear stress response and atherosclerosis.
    Int J Biochem Cell Biol Volume: 67 Page(s): 167 - 176
    10/01/2015 Authors: Dunn J; Simmons R; Thabet S; Jo H
  • Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE(-/-) Mice.
    ACS Nano Volume: 9 Page(s): 8885 - 8897
    09/22/2015 Authors: Kheirolomoom A; Kim CW; Seo JW; Kumar S; Son DJ; Gagnon MKJ; Ingham ES; Ferrara KW; Jo H
  • Flow-dependent expression of ectonucleotide tri(di)phosphohydrolase-1 and suppression of atherosclerosis.
    J Clin Invest Volume: 125 Page(s): 3027 - 3036
    08/03/2015 Authors: Kanthi Y; Hyman MC; Liao H; Baek AE; Visovatti SH; Sutton NR; Goonewardena SN; Neral MK; Jo H; Pinsky DJ
  • Non-muscle myosin heavy chain II A is a new target protein of dysfunctional vascular endothelial cells induced by disturbed flow
    Volume: 36 Page(s): 91 - 91
    08/01/2015 Authors: Kwon KH; Chung JH; Kim KC; Shim HB; Kim WJ; Kang DH; Kang SW; Jo HJ
  • Mechanosensitive PPAP2B Regulates Endothelial Responses to Atherorelevant Hemodynamic Forces.
    Circ Res Volume: 117 Page(s): e41 - e53
    07/31/2015 Authors: Wu C; Huang R-T; Kuo C-H; Kumar S; Kim CW; Lin Y-C; Chen Y-J; Birukova A; Birukov KG; Dulin NO
  • Flow-Dependent Epigenetic DNA Methylation in Endothelial Gene Expression and Atherosclerosis.
    Arterioscler Thromb Vasc Biol Volume: 35 Page(s): 1562 - 1569
    07/01/2015 Authors: Dunn J; Thabet S; Jo H
  • The Mechanosensitive microRNA-712, Induced by Disturbed Blood Flow in Endothelium, Plays a Key Role in Atherosclerosis
    Volume: 29
    04/01/2015 Authors: Kumar S; Son DJ; Kim C; Jo H
  • Identification of Candidate MicroRNA as Pathological Markers of Pediatric Heart Transplant Rejection
    Volume: 34 Page(s): S162 - S162
    04/01/2015 Authors: Bhatia AK; Phan JH; Mahle WT; Shehata B; Jo H
  • Disturbed flow induces systemic changes in metabolites in mouse plasma: a metabolomics study using ApoE/ mice with partial carotid ligation.
    Am J Physiol Regul Integr Comp Physiol Volume: 308 Page(s): R62 - R72
    01/01/2015 Authors: Go Y-M; Kim CW; Walker DI; Kang DW; Kumar S; Orr M; Uppal K; Quyyumi AA; Jo H; Jones DP
  • Vascular Proteomics Reveal Novel Proteins Involved in SMC Phenotypic Change: OLR1 as a SMC Receptor Regulating Proliferation and Inflammatory Response.
    PLoS One Volume: 10 Page(s): e0133845
    01/01/2015 Authors: Kang DH; Choi M; Chang S; Lee MY; Lee DJ; Choi K; Park J; Han EC; Hwang D; Kwon K
  • Micro-CT Technique Is Well Suited for Documentation of Remodeling Processes in Murine Carotid Arteries.
    PLoS One Volume: 10 Page(s): e0130374
    01/01/2015 Authors: Schrmann C; Gremse F; Jo H; Kiessling F; Brandes RP
  • Circulating miR-146a Shows Positive Correlation with Arterial Stiffness and Negative Correlation with Aerobic Exercise Capacity Among Healthy Adults
    Volume: 130
    11/25/2014 Authors: Rezvan A; Rooney K; Al Mheid L; Ghasemzadeh N; Jo H; Quyyumi AA; Searles CD
  • Atypical Mechanosensitive MicroRNA-712 Derived From Pre-ribosomal RNA Induces Endothelial Inflammation and Atherosclerosis
    Volume: 130
    11/25/2014 Authors: Kumar S; Son DJ; Takabe W; Kim C; Jang I; Ni CW; Alberts-Grill N; Jo H
  • Biomechanical factors in atherosclerosis: mechanisms and clinical implications.
    Eur Heart J Volume: 35 Page(s): 3013 - 3020d
    11/14/2014 Authors: Kwak BR; Bck M; Bochaton-Piallat M-L; Caligiuri G; Daemen MJAP; Davies PF; Hoefer IE; Holvoet P; Jo H; Krams R
  • Disturbed Flow Induces Systemic Changes in Metabolites in Mouse Plasma: A Metabolomics Study Using ApoE (-/-) mice with Partial Carotid Ligation
    Volume: 76 Page(s): S45 - S45
    11/01/2014 Authors: Go Y-M; Kim CW; Walker D; Kang DW; Kumar S; Orr M; Uppal K; Quyyumi A; Jo H; Jones DP
  • Functional interhemispheric asymmetry of resting state brain controlling anatomical asymmetry in schizophrenia
    Volume: 8 Page(s): 112 - 112
    11/01/2014 Authors: Kim SN; Jo HJ; Lee TY; Jang JH; Kwon JS
  • Role of flow-sensitive microRNAs in endothelial dysfunction and atherosclerosis: mechanosensitive athero-miRs.
    Arterioscler Thromb Vasc Biol Volume: 34 Page(s): 2206 - 2216
    10/01/2014 Authors: Kumar S; Kim CW; Simmons RD; Jo H
  • THE ATYPICAL MECHANOSENSITIVE MICRORNA-712 DERIVED FROM PRE-RIBOSOMAL RNA INDUCES ENDOTHELIAL INFLAMMATION AND ATHEROSCLEROSIS
    Volume: 235 Page(s): E40 - E41
    08/01/2014 Authors: Jo H; Son D; Kumar S
  • Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis.
    J Clin Invest Volume: 124 Page(s): 3187 - 3199
    07/01/2014 Authors: Dunn J; Qiu H; Kim S; Jjingo D; Hoffman R; Kim CW; Jang I; Son DJ; Kim D; Pan C
  • Prevention of abdominal aortic aneurysm by anti-microRNA-712 or anti-microRNA-205 in angiotensin II-infused mice.
    Arterioscler Thromb Vasc Biol Volume: 34 Page(s): 1412 - 1421
    07/01/2014 Authors: Kim CW; Kumar S; Son DJ; Jang I-H; Griendling KK; Jo H
  • Prevention of Abdominal Aortic Aneurysm by Anti-MiRNA-712 or Anti-miR-205 in Angiotensin II-Infused Mice
    Volume: 34
    05/01/2014 Authors: Kim C; Kumar S; Son DJ; Jang I-H; Jo H
  • ZBTB46 is a Shear Stress Sensitive Transcription Factor in Endothelial Cells
    Volume: 34
    05/01/2014 Authors: Rezvan A; Sun HY; Jo H
  • The Role of Mechanical Stimulation in Recovery of Bone Loss-High versus Low Magnitude and Frequency of Force.
    Life (Basel) Volume: 4 Page(s): 117 - 130
    04/02/2014 Authors: Nagaraja MP; Jo H
  • Development of immortalized mouse aortic endothelial cell lines.
    Vasc Cell Volume: 6 Page(s): 7
    04/01/2014 Authors: Ni C-W; Kumar S; Ankeny CJ; Jo H
  • Disturbed flow enhances inflammatory signaling and atherogenesis by increasing thioredoxin-1 level in endothelial cell nuclei.
    PLoS One Volume: 9 Page(s): e108346
    01/01/2014 Authors: Go Y-M; Son DJ; Park H; Orr M; Hao L; Takabe W; Kumar S; Kang DW; Kim CW; Jo H
  • Flow-dependent regulation of genome-wide mRNA and microRNA expression in endothelial cells in vivo.
    Sci Data Volume: 1 Page(s): 140039
    01/01/2014 Authors: Kumar S; Kim CW; Son DJ; Ni CW; Jo H
  • Fluid Mechanics, Arterial Disease, and Gene Expression.
    Annu Rev Fluid Mech Volume: 46 Page(s): 591 - 614
    01/01/2014 Authors: Tarbell JM; Shi Z-D; Dunn J; Jo H
  • MECHANOSENSITIVE MICRORNAS IN ENDOTHELIAL INFLAMMATION AND ATHEROSCLEROSIS: PREVENTION OF ATHEROSCLEROSIS BY ANTI-MIR-712 IN MICE
    CARDIOLOGY Volume: 128 Page(s): 129 - 129
    01/01/2014 Authors: Jo H
  • Inhibition of Mechanosensitive MicroRNA, mir-712 Decreases Endothelial Dysfunction and Atherosclerosis
    Volume: 128
    11/26/2013 Authors: Kumar S; Son DJ; Takabe W; Kim C; Ni CW; Alberts-Grill N; Kim SO; Kim WK; Seo JW; Ferrara K
  • Disturbed Flow Upregulates Dnmt1 Expression in Endothelial Cells, Which Induces Genome-Wide DNA Methylation Pattern Changes and Atherosclerosis in Mice
    Volume: 128
    11/26/2013 Authors: Dunn J; Kim S; Qiu H; Kim C; Hoffman R; Jang I; Jo H
  • MicroRNA-712 Induced by Angiotensin II Plays a Key Role in Development of Abdominal Aortic Aneurysm in Mouse
    Volume: 128
    11/26/2013 Authors: Kim C; Kumar S; Son DJ; Jang I-H; Jo H
  • The bone morphogenic protein inhibitor, noggin, reduces glycemia and vascular inflammation in db/db mice.
    Am J Physiol Heart Circ Physiol Volume: 305 Page(s): H747 - H755
    09/01/2013 Authors: Koga M; Engberding N; Dikalova AE; Chang KH; Seidel-Rogol B; Long JS; Lassgue B; Jo H; Griendling KK
  • Vascular injury involves the overoxidation of peroxiredoxin type II and is recovered by the peroxiredoxin activity mimetic that induces reendothelialization.
    Circulation Volume: 128 Page(s): 834 - 844
    08/20/2013 Authors: Kang DH; Lee DJ; Kim J; Lee JY; Kim H-W; Kwon K; Taylor WR; Jo H; Kang SW
  • Laminar shear stress upregulates endothelial Ca-activated K channels KCa2.3 and KCa3.1 via a Ca/calmodulin-dependent protein kinase kinase/Akt/p300 cascade.
    Am J Physiol Heart Circ Physiol Volume: 305 Page(s): H484 - H493
    08/15/2013 Authors: Takai J; Santu A; Zheng H; Koh SD; Ohta M; Filimban LM; Lematre V; Teraoka R; Jo H; Miura H
  • The role of the vascular dendritic cell network in atherosclerosis.
    Am J Physiol Cell Physiol Volume: 305 Page(s): C1 - 21
    07/01/2013 Authors: Alberts-Grill N; Denning TL; Rezvan A; Jo H
  • Aortic valve: mechanical environment and mechanobiology.
    Ann Biomed Eng Volume: 41 Page(s): 1331 - 1346
    07/01/2013 Authors: Arjunon S; Rathan S; Jo H; Yoganathan AP
  • Anti-inflammatory and antiatherogenic role of BMP receptor II in endothelial cells.
    Arterioscler Thromb Vasc Biol Volume: 33 Page(s): 1350 - 1359
    06/01/2013 Authors: Kim CW; Song H; Kumar S; Nam D; Kwon HS; Chang KH; Son DJ; Kang D-W; Brodie SA; Weiss D
  • The atypical mechanosensitive microRNA-712 derived from pre-ribosomal RNA induces endothelial inflammation and atherosclerosis.
    Nat Commun Volume: 4 Page(s): 3000
    01/01/2013 Authors: Son DJ; Kumar S; Takabe W; Kim CW; Ni C-W; Alberts-Grill N; Jang I-H; Kim S; Kim W; Won Kang S
  • Strain magnitude-dependent calcific marker expression in valvular and vascular cells.
    Cells Tissues Organs Volume: 197 Page(s): 372 - 383
    01/01/2013 Authors: Ferdous Z; Jo H; Nerem RM
  • Angiotensin II induces DNA damage via AT1 receptor and NADPH oxidase isoform Nox4.
    Mutagenesis Volume: 27 Page(s): 673 - 681
    11/01/2012 Authors: Fazeli G; Stopper H; Schinzel R; Ni C-W; Jo H; Schupp N
  • Piperlongumine inhibits atherosclerotic plaque formation and vascular smooth muscle cell proliferation by suppressing PDGF receptor signaling.
    Biochem Biophys Res Commun Volume: 427 Page(s): 349 - 354
    10/19/2012 Authors: Son DJ; Kim SY; Han SS; Kim CW; Kumar S; Park BS; Lee SE; Yun YP; Jo H; Park YH
  • Maturing EPCs into endothelial cells: may the force be with the EPCs: focus on "Fluid shear stress induces differentiation of circulating phenotype endothelial progenitor cells".
    Am J Physiol Cell Physiol Volume: 303 Page(s): C589 - C591
    09/15/2012 Authors: Ankeny RF; Ankeny CJ; Nerem RM; Jo H
  • 8-Hydroxy-2-deoxyguanosine prevents plaque formation and inhibits vascular smooth muscle cell activation through Rac1 inactivation.
    Free Radic Biol Med Volume: 53 Page(s): 109 - 121
    07/01/2012 Authors: Huh JY; Son DJ; Lee Y; Lee J; Kim B; Lee HM; Jo H; Choi S; Ha H; Chung M-H
  • Identification of target proteins of shear stress-related miRNAs in endothelial cells
    Volume: 26
    04/01/2012 Authors: Park Y; Kang D-H; Son D; Jo H; Kang SW
  • Dynamic immune cell accumulation during flow-induced atherogenesis in mouse carotid artery: an expanded flow cytometry method.
    Arterioscler Thromb Vasc Biol Volume: 32 Page(s): 623 - 632
    03/01/2012 Authors: Alberts-Grill N; Rezvan A; Son DJ; Qiu H; Kim CW; Kemp ML; Weyand CM; Jo H
  • Serum BMP-4 levels in relation to arterial stiffness and carotid atherosclerosis in patients with Type 2 diabetes.
    Biomark Med Volume: 5 Page(s): 827 - 835
    12/01/2011 Authors: Son J-W; Jang E-H; Kim M-K; Baek K-H; Song K-H; Yoon K-H; Cha B-Y; Son H-Y; Lee K-W; Jo H
  • Cathepsin S Deficiency Attenuates AngiotensinII-induced Abdominal Aortic Aneurysm Without Altering Hypertension in ApoE Knockout Mice
    Volume: 124
    11/22/2011 Authors: Kim C; Son D; Albert-Grill N; Kumar S; Jo H
  • Bmp Receptor II Reduction Causes Endothelial Inflammation in vitro and Increases Atherosclerosis in Apoe Knockout Mice
    Volume: 124
    11/22/2011 Authors: Kim C; Song H; Son D; Kumar S; Jo H
  • Thioredoxin Overexpression in Cell Nuclei Potentiates Atherosclerosis Via Activation of NF-kappa B Transcription Factor
    Volume: 51 Page(s): S104 - S104
    11/01/2011 Authors: Go Y-M; Son DJ; Park H; Kang DW; Kim CW; Orr M; Jo H; Jones DP
  • Peroxiredoxin 2 deficiency exacerbates atherosclerosis in apolipoprotein E-deficient mice.
    Circ Res Volume: 109 Page(s): 739 - 749
    09/16/2011 Authors: Park J-G; Yoo J-Y; Jeong S-J; Choi J-H; Lee M-R; Lee M-N; Hwa Lee J; Kim HC; Jo H; Yu D-Y
  • Discovery of shear- and side-specific mRNAs and miRNAs in human aortic valvular endothelial cells.
    Am J Physiol Heart Circ Physiol Volume: 301 Page(s): H856 - H867
    09/01/2011 Authors: Holliday CJ; Ankeny RF; Jo H; Nerem RM
  • Animal, in vitro, and ex vivo models of flow-dependent atherosclerosis: role of oxidative stress.
    Antioxid Redox Signal Volume: 15 Page(s): 1433 - 1448
    09/01/2011 Authors: Rezvan A; Ni C-W; Alberts-Grill N; Jo H
  • Redox going with vascular shear stress.
    Antioxid Redox Signal Volume: 15 Page(s): 1367 - 1368
    09/01/2011 Authors: Noguchi N; Jo H
  • 8-Hydroxy-2-Deoxyguanosine Prevents Plaque Formation in a Partial Ligated ApoE Knockout Mouse, an Acute Model of Atherosclerosis
    Volume: 60 Page(s): A146 - A146
    07/01/2011 Authors: Huh JY; Jo H; Chung M-H; Ha H
  • Tetrahydrobiopterin deficiency and nitric oxide synthase uncoupling contribute to atherosclerosis induced by disturbed flow.
    Volume: 31 Page(s): 1547 - 1554
    07/01/2011 Authors: Li L; Chen W; Rezvan A; Jo H; Harrison DG
  • The effects of combined cyclic stretch and pressure on the aortic valve interstitial cell phenotype.
    Ann Biomed Eng Volume: 39 Page(s): 1654 - 1667
    06/01/2011 Authors: Thayer P; Balachandran K; Rathan S; Yap CH; Arjunon S; Jo H; Yoganathan AP
  • Disturbed flow: p53 SUMOylation in the turnover of endothelial cells.
    J Cell Biol Volume: 193 Page(s): 805 - 807
    05/30/2011 Authors: Takabe W; Alberts-Grill N; Jo H
  • MicroRNA-663 upregulated by oscillatory shear stress plays a role in inflammatory response of endothelial cells.
    Am J Physiol Heart Circ Physiol Volume: 300 Page(s): H1762 - H1769
    05/01/2011 Authors: Ni C-W; Qiu H; Jo H
  • Angiotensin type I receptor blockade in conjunction with enhanced Akt activation restores coronary collateral growth in the metabolic syndrome.
    Am J Physiol Heart Circ Physiol Volume: 300 Page(s): H1938 - H1949
    05/01/2011 Authors: Jadhav R; Dodd T; Smith E; Bailey E; Delucia AL; Russell JC; Madison R; Potter B; Walsh K; Jo H
  • Differences in valvular and vascular cell responses to strain in osteogenic media.
    Biomaterials Volume: 32 Page(s): 2885 - 2893
    04/01/2011 Authors: Ferdous Z; Jo H; Nerem RM
  • Inorganic phosphate induces mammalian growth plate chondrocyte apoptosis in a mitochondrial pathway involving nitric oxide and JNK MAP kinase.
    Calcif Tissue Int Volume: 88 Page(s): 96 - 108
    02/01/2011 Authors: Zhong M; Carney DH; Jo H; Boyan BD; Schwartz Z
  • Preferential activation of SMAD1/5/8 on the fibrosa endothelium in calcified human aortic valves--association with low BMP antagonists and SMAD6.
    PLoS One Volume: 6 Page(s): e20969
    01/01/2011 Authors: Ankeny RF; Thourani VH; Weiss D; Vega JD; Taylor WR; Nerem RM; Jo H
  • Detection of low levels of nitric oxide using an electrochemical sensor.
    Volume: 704 Page(s): 81 - 89
    01/01/2011 Authors: Boo YC; Mun GI; Tressel SL; Jo H
  • Endothelial metallothionein expression and intracellular free zinc levels are regulated by shear stress.
    Am J Physiol Cell Physiol Volume: 299 Page(s): C1461 - C1467
    12/01/2010 Authors: Conway DE; Lee S; Eskin SG; Shah AK; Jo H; McIntire LV
  • Three-Dimensional Network of Lipid Crystals and Vaso Vasorum Based on Coherent Anti-Stokes Raman Spectroscopy Imaging
    CIRCULATION Volume: 122
    11/23/2010 Authors: Kim SR; Lee E-S; Nam D; Jo H; Moon DW; Kim S-H
  • Discovery of Novel Mechanosensitive mRNA and miRNA in Vivo Using Mouse Carotid Artery Endothelium Exposed to Disturbed Flow
    Volume: 122
    11/23/2010 Authors: Ni C-W; Qiu H; Rezvan A; Kwon K; Nam D; Son DJ; Jo H
  • Discovery of Mechanosensitive Genes by Genomewide Microarray Analysis Using Endothelial RNA from Mouse Carotid Exposed to Disturbed Flow in Vivo
    Volume: 30 Page(s): E291 - E291
    11/01/2010 Authors: Ni C-W; Qiu H; Rezvan A; Kwon K; Nam D; Jo H
  • Side-Dependent Activation of Bone Morphogenic Protein Pathway in Human Aortic Valves
    Volume: 30 Page(s): E307 - E308
    11/01/2010 Authors: Ankeny RF; Nerem R; Jo H
  • Identification of Shear-Sensitive miRNAs in Endothelial Cells: Role of mir-663 in Monocyte Adhesion Response
    Volume: 30 Page(s): E224 - E224
    11/01/2010 Authors: Ni C-W; Jo H
  • Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow.
    Blood Volume: 116 Page(s): e66 - e73
    10/14/2010 Authors: Ni C-W; Qiu H; Rezvan A; Kwon K; Nam D; Son DJ; Visvader JE; Jo H
  • X-linked inhibitor of apoptosis protein controls alpha5-integrin-mediated cell adhesion and migration.
    Am J Physiol Heart Circ Physiol Volume: 299 Page(s): H300 - H309
    08/01/2010 Authors: Kim J; Ahn S; Ko Y-G; Boo YC; Chi S-G; Ni C-W; Go Y-M; Jo H; Park H
  • Elevated cyclic stretch induces aortic valve calcification in a bone morphogenic protein-dependent manner.
    Am J Pathol Volume: 177 Page(s): 49 - 57
    07/01/2010 Authors: Balachandran K; Sucosky P; Jo H; Yoganathan AP
  • A model of disturbed flow-induced atherosclerosis in mouse carotid artery by partial ligation and a simple method of RNA isolation from carotid endothelium.
    J Vis Exp
    06/22/2010 Authors: Nam D; Ni C-W; Rezvan A; Suo J; Budzyn K; Llanos A; Harrison DG; Giddens DP; Jo H
  • HuR regulates the expression of stress-sensitive genes and mediates inflammatory response in human umbilical vein endothelial cells.
    Proc Natl Acad Sci U S A Volume: 107 Page(s): 6858 - 6863
    04/13/2010 Authors: Rhee WJ; Ni C-W; Zheng Z; Chang K; Jo H; Bao G
  • Oral Tetrahydrobiopterin Treatment Prevents Accelerated Atherosclerosis Caused by Oscillatory Shear Stress
    Volume: 24
    04/01/2010 Authors: Li L; Rezvan A; Chen W; Jo H; Harrison DG
  • Laminar Shear Stress Up-regulates Endothelial CD73 Expression by Activating Calmodulin-dependent Kinase Kinase
    FASEB JOURNAL Volume: 24
    04/01/2010 Authors: Li W; Ohta M; Nandedkar S; Fan F; Jo H; Miura H
  • NO negatively regulates cell surface expression of CD73 in sheared endothelial cells
    FASEB JOURNAL Volume: 24
    04/01/2010 Authors: Fan F; Ohta M; Nandedkar S; Li W; Jo H; Miura H
  • Shear stress and plaque development.
    Expert Rev Cardiovasc Ther Volume: 8 Page(s): 545 - 556
    04/01/2010 Authors: Dhawan SS; Avati Nanjundappa RP; Branch JR; Taylor WR; Quyyumi AA; Jo H; McDaniel MC; Suo J; Giddens D; Samady H
  • GTP cyclohydrolase I phosphorylation and interaction with GTP cyclohydrolase feedback regulatory protein provide novel regulation of endothelial tetrahydrobiopterin and nitric oxide.
    Circ Res Volume: 106 Page(s): 328 - 336
    02/05/2010 Authors: Li L; Rezvan A; Salerno JC; Husain A; Kwon K; Jo H; Harrison DG; Chen W
  • Systems analysis of the role of bone morphogenic protein 4 in endothelial inflammation.
    Ann Biomed Eng Volume: 38 Page(s): 291 - 307
    02/01/2010 Authors: Yin W; Jo H; Voit EO
  • Intimal cushions and endothelial nuclear elongation around mouse aortic branches and their spatial correspondence with patterns of lipid deposition.
    Am J Physiol Heart Circ Physiol Volume: 298 Page(s): H536 - H544
    02/01/2010 Authors: Bond AR; Ni C-W; Jo H; Weinberg PD
  • Proposal of the standard-based method for communication safety enhancement in railway signalling systems
    Volume: 114 Page(s): 863 - 873
    01/01/2010 Authors: Jo H-J; Hwang J-G; Kim B-H; Lee K-M; Kim Y-K
  • Laminar Shear Stress Upregulates Endothelial KCa2.3 and KCa3.1 Calcium-activated Potassium Channels via Activating Calmodulin-dependent Protein Kinase Kinase and AMP-activated Protein Kinase
    Volume: 120 Page(s): S1106 - S1107
    11/03/2009 Authors: Ohta M; Nandedkar S; Jo H; Miura H
  • Blockade of KCa3.1 Calcium-activated Potassium Channels Prevents Endothelial Inflammation
    Volume: 120 Page(s): S1114 - S1114
    11/03/2009 Authors: Ohta M; Nandedkar S; Wulff H; Jo H; Miura H
  • Partial carotid ligation is a model of acutely induced disturbed flow, leading to rapid endothelial dysfunction and atherosclerosis.
    Am J Physiol Heart Circ Physiol Volume: 297 Page(s): H1535 - H1543
    10/01/2009 Authors: Nam D; Ni C-W; Rezvan A; Suo J; Budzyn K; Llanos A; Harrison D; Giddens D; Jo H
  • Angiopoietin-2 Stimulates Blood Flow Recovery After Femoral Artery Occlusion by Inducing Inflammation and Arteriogenesis
    Volume: 29 Page(s): E93 - E93
    07/01/2009 Authors: Tressel S; Ni C-W; Jo H
  • Activation of Bone Morphogenic Pathway in Human Aortic Valve Endothelial Cells
    Volume: 29 Page(s): E49 - E49
    07/01/2009 Authors: Ankeny RF; Gerbig SE; Nerem RM; Jo H
  • Partial Ligation of Carotid Artery Induces Flow Reduction and Reversal, Causing Rapid Atherosclerosis Development in a NADPH Oxidase-Dependent Manner
    Volume: 29 Page(s): E39 - E40
    07/01/2009 Authors: Nam D; Ni C-W; Rezvan A; Jo H
  • Redox-sensitive Akt and Src regulate coronary collateral growth in metabolic syndrome.
    Am J Physiol Heart Circ Physiol Volume: 296 Page(s): H1811 - H1821
    06/01/2009 Authors: Reed R; Potter B; Smith E; Jadhav R; Villalta P; Jo H; Rocic P
  • Expression of CYP1A1 and CYP1B1 in human endothelial cells: regulation by fluid shear stress.
    Cardiovasc Res Volume: 81 Page(s): 669 - 677
    03/01/2009 Authors: Conway DE; Sakurai Y; Weiss D; Vega JD; Taylor WR; Jo H; Eskin SG; Marcus CB; McIntire LV
  • Elevated cyclic stretch alters matrix remodeling in aortic valve cusps: implications for degenerative aortic valve disease.
    Am J Physiol Heart Circ Physiol Volume: 296 Page(s): H756 - H764
    03/01/2009 Authors: Balachandran K; Sucosky P; Jo H; Yoganathan AP
  • Low magnitude and high frequency mechanical loading prevents decreased bone formation responses of 2T3 preosteoblasts.
    J Cell Biochem Volume: 106 Page(s): 306 - 316
    02/01/2009 Authors: Patel MJ; Chang KH; Sykes MC; Talish R; Rubin C; Jo H
  • Altered shear stress stimulates upregulation of endothelial VCAM-1 and ICAM-1 in a BMP-4- and TGF-beta1-dependent pathway.
    Arterioscler Thromb Vasc Biol Volume: 29 Page(s): 254 - 260
    02/01/2009 Authors: Sucosky P; Balachandran K; Elhammali A; Jo H; Yoganathan AP
  • Angiopoietin-2 stimulates blood flow recovery after femoral artery occlusion by inducing inflammation and arteriogenesis.
    Arterioscler Thromb Vasc Biol Volume: 28 Page(s): 1989 - 1995
    11/01/2008 Authors: Tressel SL; Kim H; Ni C-W; Chang K; Velasquez-Castano JC; Taylor WR; Yoon Y-S; Jo H
  • Laminar shear stress inhibits lipid peroxidation induced by high glucose plus arachidonic acid in endothelial cells.
    Am J Physiol Heart Circ Physiol Volume: 295 Page(s): H1966 - H1973
    11/01/2008 Authors: Mun GI; An SM; Park H; Jo H; Boo YC
  • Regulation OF Entpdase1 (CD39) Expression by Fluid-phase Shear Forces
    Volume: 118 Page(s): S409 - S409
    10/28/2008 Authors: Hyman MC; Ni C-W; Visovatti SH; Nam D; Neral MK; Jo H; Pinsky DJ
  • Cyclic Stretch and TGF-beta 1 Induce Aortic Valve Calcification via a Bone Morphogenic Protein Moderated Pathway
    Volume: 118 Page(s): S1014 - S1014
    10/28/2008 Authors: Balachandran K; Sucosky P; Jo H; Yoganathan A
  • Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells.
    Am J Physiol Heart Circ Physiol Volume: 295 Page(s): H569 - H577
    08/01/2008 Authors: Csiszar A; Labinskyy N; Jo H; Ballabh P; Ungvari Z
  • Design of an ex vivo culture system to investigate the effects of shear stress on cardiovascular tissue.
    J Biomech Eng Volume: 130 Page(s): 035001
    06/01/2008 Authors: Sucosky P; Padala M; Elhammali A; Balachandran K; Jo H; Yoganathan AP
  • Inhibition of angiopoietin-2 impairs blood flow recovery during hindlimb ischemia through the inhibition of arteriogenesis
    Volume: 28 Page(s): E112 - E113
    06/01/2008 Authors: Tressel S; Jo H
  • X-linked inhibitor of apoptosis protein is an important regulator of vascular endothelial growth factor-dependent bovine aortic endothelial cell survival.
    Circ Res Volume: 102 Page(s): 896 - 904
    04/25/2008 Authors: Kim J; Park J; Choi S; Chi S-G; Mowbray AL; Jo H; Park H
  • Down-regulation of BMP-4 Expression in Coronary Arterial Endothelial Cells: Role of Shear Stress and the cAMP/PKA Pathway
    FASEB JOURNAL Volume: 22
    04/01/2008 Authors: Csiszar A; Labinskyy N; Smith KE; Rivera A; Bakker ENTP; Jo H; Gardner J; Ungvari Z
  • Peroxiredoxin 1 is Upregulated by Laminar Shear Stress via Nrf2 Transcription Factor
    Volume: 22
    04/01/2008 Authors: Mowbray AL; Chen X-L; Kang SW; Rhee SG; Jo H
  • Mechanical loading prevents decreased bone formation responses of osteoblasts by a bone morphogenic protein-dependent mechanism
    FASEB JOURNAL Volume: 22
    04/01/2008 Authors: Patel M; Talish R; Rubin C; Jo H
  • Angiopoietin-2 inhibition impairs blood flow recovery during hindlimb ischemia
    FASEB JOURNAL Volume: 22
    04/01/2008 Authors: Tressel SL; Jo H
  • Target accessibility and signal specificity in live-cell detection of BMP-4 mRNA using molecular beacons.
    Nucleic Acids Res Volume: 36 Page(s): e30
    03/01/2008 Authors: Rhee WJ; Santangelo PJ; Jo H; Bao G
  • Laminar shear stress up-regulates peroxiredoxins (PRX) in endothelial cells: PRX 1 as a mechanosensitive antioxidant.
    J Biol Chem Volume: 283 Page(s): 1622 - 1627
    01/18/2008 Authors: Mowbray AL; Kang D-H; Rhee SG; Kang SW; Jo H
  • Valvular chondromodulin-1 expression is down-regulated in a rabbit model of infective endocarditis - Meeting discussion
    JOURNAL OF HEART VALVE DISEASE Volume: 16 Page(s): 630 - 630
    11/01/2007 Authors: Jo H; Grammer JB; Chester A; Yoganathan AP; Zilla P; Krenz M
  • The role of peroxiredoxins as mechanosensitive antioxidants in endothelial cells
    Volume: 116 Page(s): 182 - 182
    10/16/2007 Authors: Mowbray A; Kang SW; Rhee SG; Jo H
  • Protein disulfide isomerase is involved in redox regulation of nitric oxide output during laminar shear stress in endothelial cells
    Volume: 116 Page(s): 149 - 149
    10/16/2007 Authors: Fernandes DC; Santos CX; Jo H; Laurindo FR
  • Laminar shear inhibits tubule formation and migration of endothelial cells by an angiopoietin-2 dependent mechanism.
    Arterioscler Thromb Vasc Biol Volume: 27 Page(s): 2150 - 2156
    10/01/2007 Authors: Tressel SL; Huang R-P; Tomsen N; Jo H
  • NFKB1 promoter variation implicates shear-induced NOS3 gene expression and endothelial function in prehypertensives and stage I hypertensives.
    Am J Physiol Heart Circ Physiol Volume: 293 Page(s): H2320 - H2327
    10/01/2007 Authors: Park J-Y; Farrance IKG; Fenty NM; Hagberg JM; Roth SM; Mosser DM; Wang MQ; Jo H; Okazaki T; Brant SR
  • Bone morphogenic protein antagonists are coexpressed with bone morphogenic protein 4 in endothelial cells exposed to unstable flow in vitro in mouse aortas and in human coronary arteries: role of bone morphogenic protein antagonists in inflammation and atherosclerosis.
    Circulation Volume: 116 Page(s): 1258 - 1266
    09/11/2007 Authors: Chang K; Weiss D; Suo J; Vega JD; Giddens D; Taylor WR; Jo H
  • Caveolin-1 knockout mice have increased bone size and stiffness.
    J Bone Miner Res Volume: 22 Page(s): 1408 - 1418
    09/01/2007 Authors: Rubin J; Schwartz Z; Boyan BD; Fan X; Case N; Sen B; Drab M; Smith D; Aleman M; Wong KL
  • Fluid shear stress and mechanical strain induce a similar osteogenic gene response via divergent signaling pathways
    Volume: 22 Page(s): S228 - S228
    09/01/2007 Authors: Case N; Xie Z; Sen B; Ma M; Jo H; Rubin J
  • Mechanical activation of beta-catenin is enhanced after Caveolin-1 knock-down
    Volume: 22 Page(s): S358 - S358
    09/01/2007 Authors: Ma M; Sen B; Case N; Xie Z; Jo H; Gross T; Rubin J
  • Emerging role of IGF-1R in stretch-induced neointimal hyperplasia in venous grafts.
    Arterioscler Thromb Vasc Biol Volume: 27 Page(s): 1679 - 1681
    08/01/2007 Authors: Song H; Mowbray AL; Sykes MC; Jo H
  • Loss of BMPRII in endothelium induces inflammation in vitro and correlates with atherosclerosis progression in human coronary arteries
    Volume: 27 Page(s): E67 - E67
    06/01/2007 Authors: Song H; Weiss D; Vega JD; Taylor WR; Jo H
  • Identification of mechanosensitive genes in osteoblasts by comparative microarray studies using the rotating wall vessel and the random positioning machine.
    J Cell Biochem Volume: 101 Page(s): 587 - 599
    06/01/2007 Authors: Patel MJ; Liu W; Sykes MC; Ward NE; Risin SA; Risin D; Jo H
  • Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes.
    Am J Physiol Heart Circ Physiol Volume: 292 Page(s): H2073 - H2082
    05/01/2007 Authors: San Martn A; Du P; Dikalova A; Lassgue B; Aleman M; Gngora MC; Brown K; Joseph G; Harrison DG; Taylor WR
  • Downregulation of bone morphogenetic protein 4 expression in coronary arterial endothelial cells: role of shear stress and the cAMP/protein kinase A pathway.
    Arterioscler Thromb Vasc Biol Volume: 27 Page(s): 776 - 782
    04/01/2007 Authors: Csiszar A; Labinskyy N; Smith KE; Rivera A; Bakker ENTP; Jo H; Gardner J; Orosz Z; Ungvari Z
  • An improved method to measure nitrate/nitrite with an NO-selective electrochemical sensor.
    Nitric Oxide Volume: 16 Page(s): 306 - 312
    03/01/2007 Authors: Boo YC; Tressel SL; Jo H
  • Expression of cathepsin K is regulated by shear stress in cultured endothelial cells and is increased in endothelium in human atherosclerosis.
    Am J Physiol Heart Circ Physiol Volume: 292 Page(s): H1479 - H1486
    03/01/2007 Authors: Platt MO; Ankeny RF; Shi G-P; Weiss D; Vega JD; Taylor WR; Jo H
  • Reversible glutathiolation of caspase-3 by glutaredoxin as a novel redox signaling mechanism in tumor necrosis factor-alpha-induced cell death.
    Circ Res Volume: 100 Page(s): 152 - 154
    02/02/2007 Authors: Sykes MC; Mowbray AL; Jo H
  • Protein disulfide isomerase is involved in the redox regulation of nitric oxide output during laminar shear stress in endothelial cells
    Volume: 43 Page(s): S165 - S166
    01/01/2007 Authors: Fernandes DC; Santos CX; Jo H; Laurindo FR
  • Safety characteristics analysis of Korean standard communication protocol for railway signalling
    Volume: 96 Page(s): 603 - 613
    01/01/2007 Authors: Hwang J-G; Jo H-J
  • An ex vivo study of the biological properties of porcine aortic valves in response to circumferential cyclic stretch.
    Ann Biomed Eng Volume: 34 Page(s): 1655 - 1665
    11/01/2006 Authors: Balachandran K; Konduri S; Sucosky P; Jo H; Yoganathan AP
  • The BMP receptor II is localized in the endothelial cell junction and plays a paradoxical role as both a pro- and an anti-inflammatory regulator
    Volume: 114 Page(s): 320 - 320
    10/31/2006 Authors: Song H; Jo H
  • Oscillatory and laminar shear stress inversely regulate cathepsins K and S and cystatin C in mouse aortic enclothelial cells (MAEC)
    Volume: 114 Page(s): 280 - 280
    10/31/2006 Authors: Platt M; Ankeny RF; Jo H
  • Regulation of growth plate chondrocytes by 1,25-dihydroxyvitamin D3 requires caveolae and caveolin-1.
    J Bone Miner Res Volume: 21 Page(s): 1637 - 1647
    10/01/2006 Authors: Boyan BD; Wong KL; Wang L; Yao H; Guldberg RE; Drab M; Jo H; Schwartz Z
  • Cyclic pressure and shear stress regulate matrix metalloproteinases and cathepsin activity in porcine aortic valves.
    J Heart Valve Dis Volume: 15 Page(s): 622 - 629
    09/01/2006 Authors: Platt MO; Xing Y; Jo H; Yoganathan AP
  • Caveolin-1 scaffolds are not necessary for lipid raft microdomains involved in the mechanical strain response.
    Volume: 21 Page(s): S370 - S370
    09/01/2006 Authors: Case N; Jo H; Rahnert J; Fan X; Gross T; Rubin J
  • Early determinants of H2O2-induced endothelial dysfunction.
    Free Radic Biol Med Volume: 41 Page(s): 810 - 817
    09/01/2006 Authors: Boulden BM; Widder JD; Allen JC; Smith DA; Al-Baldawi RN; Harrison DG; Dikalov SI; Jo H; Dudley SC
  • Laminar shear stress inhibits cathepsin L activity in endothelial cells.
    Arterioscler Thromb Vasc Biol Volume: 26 Page(s): 1784 - 1790
    08/01/2006 Authors: Platt MO; Ankeny RF; Jo H
  • Ascorbic acid synthesis due to L-gulono-1,4-lactone oxidase expression enhances NO production in endothelial cells.
    Biochem Biophys Res Commun Volume: 345 Page(s): 1657 - 1662
    07/14/2006 Authors: Kim HJ; Lee SI; Lee D-H; Smith D; Jo H; Schellhorn HE; Boo YC
  • Coordinated regulation of endothelial nitric oxide synthase activity by phosphorylation and subcellular localization.
    Free Radic Biol Med Volume: 41 Page(s): 144 - 153
    07/01/2006 Authors: Boo YC; Kim HJ; Song H; Fulton D; Sessa W; Jo H
  • Bone morphogenic protein-4 induces hypertension in mice: role of noggin, vascular NADPH oxidases, and impaired vasorelaxation.
    Circulation Volume: 113 Page(s): 2818 - 2825
    06/20/2006 Authors: Miriyala S; Gongora Nieto MC; Mingone C; Smith D; Dikalov S; Harrison DG; Jo H
  • A Promoter Polymorphism Regulates NFKB1 Gene Transactivity in Human Endothelial Cells under Laminar Shear Stress
    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE Volume: 38 Page(s): S4 - S4
    05/01/2006 Authors: Park JY; Farrance IK; Jo H; Brant SR; Roth SM; Brown MD
  • Laminar shear stress inhibits cathepsin L activity in endothelial cells
    Volume: 26 Page(s): E89 - E89
    05/01/2006 Authors: Platt MO; Ankeny R; Jo HJ
  • Selective regulation of bone morphogenetic protein-4 by reactive oxygen species in type 2 diabetic mice: Relationship to NADPH oxidases
    Volume: 26 Page(s): E84 - E84
    05/01/2006 Authors: Martin AS; Du PF; Dikalova A; Aleman M; Jo H; Griendling KK
  • Plasma membrane requirements for 1alpha,25(OH)2D3 dependent PKC signaling in chondrocytes and osteoblasts.
    Steroids Volume: 71 Page(s): 286 - 290
    04/01/2006 Authors: Boyan BD; Wang L; Wong KL; Jo H; Schwartz Z
  • Gene expression profiles of 2T3 preosteoblasts in microgravity analog systems: Comparison of the random positioning machine and the rotating wall vessel bioreactor
    Volume: 20 Page(s): A1250 - A1250
    03/07/2006 Authors: Patel MJ; Risin D; Jo H
  • Laminar shear stress inhibits cathepsin L activity in endothelial cells (EC)
    Volume: 20 Page(s): A1098 - A1099
    03/07/2006 Authors: Platt MO; Ankeny R; Delgado-Reyes C; Song H; Smith D; Jo H
  • Peroxiredoxins as mechanosensitive antioxidants in a subcellular-specific manner
    Volume: 20 Page(s): A1453 - A1453
    03/07/2006 Authors: Mowbray AL; Kang SW; Jo H
  • Oscillatory shear stress promotes endothelial cell migration and angiogenesis
    Volume: 20 Page(s): A289 - A289
    03/06/2006 Authors: Tressel SL; Huan RP; Jo H
  • Mechanical inhibition of RANKL expression is regulated by H-Ras-GTPase.
    J Biol Chem Volume: 281 Page(s): 1412 - 1418
    01/20/2006 Authors: Rubin J; Murphy TC; Rahnert J; Song H; Nanes MS; Greenfield EM; Jo H; Fan X
  • Caveolin-1 is transiently dephosphorylated by shear stress-activated protein tyrosine phosphatase mu.
    Biochem Biophys Res Commun Volume: 339 Page(s): 737 - 741
    01/20/2006 Authors: Shin J; Jo H; Park H
  • Peroxiredoxins as mechanosensitive antioxidants in a subcellular-speciflc manner
    Volume: 41 Page(s): S41 - S41
    01/01/2006 Authors: Mowbray AL; Kang S-W; Rhee SG; Jo H
  • Embryonic stem cell-derived endothelial cells may lack complete functional maturation in vitro.
    J Vasc Res Volume: 43 Page(s): 411 - 421
    01/01/2006 Authors: McCloskey KE; Smith DA; Jo H; Nerem RM
  • Effect of p47phox-based NADPH oxidases on shear stress-dependent gene expression profiles in endothelial cells
    Volume: 41 Page(s): S43 - S43
    01/01/2006 Authors: Sykes M; Jo H
  • The X-linked inhibitor of apoptosis modulates vascular functions through its association with caveolin-1
    Volume: 41 Page(s): S50 - S50
    01/01/2006 Authors: Park H; Kim J; Park J; Jo H
  • Role of NADPH oxidases in disturbed flow- and BMP4- induced inflammation and atherosclerosis.
    Antioxid Redox Signal Volume: 8 Page(s): 1609 - 1619
    01/01/2006 Authors: Jo H; Song H; Mowbray A
  • Transcriptional profiles of valvular and vascular endothelial cells reveal phenotypic differences: influence of shear stress.
    Arterioscler Thromb Vasc Biol Volume: 26 Page(s): 69 - 77
    01/01/2006 Authors: Butcher JT; Tressel S; Johnson T; Turner D; Sorescu G; Jo H; Nerem RM
  • Caveolin-1 deficient mice have bigger bones.
    Volume: 20 Page(s): S46 - S46
    09/01/2005 Authors: Rubin J; Schwartz Z; Wong K; Wang L; Drab M; Smith D; Jo H; Boyan BD; Gross T
  • Intact caveolae and caveolin-1 are required for 1 alpha,25(OH)(2)D-3 regulation of the growth plate.
    Volume: 20 Page(s): S199 - S199
    09/01/2005 Authors: Boyan BD; Wang L; Wong K; Yao L; Guldberg RE; Jo H; Schwartz Z
  • Mechanical inhibition of RANKL expression is regulated by H-Ras-GTPase in a lipid raft dependent manner.
    Volume: 20 Page(s): S73 - S73
    09/01/2005 Authors: Rubin J; Murphy TC; Rahnert J; Nanes MS; Greenfield EM; Jo H; Fan X
  • Caveolin-1 deficient mice exhibit sexually dimorphic changes in bone phenotype: Micro-CT and biomechanical and biomechanical analysis.
    Volume: 20 Page(s): S99 - S99
    09/01/2005 Authors: Yao H; Schwartz Z; Jo H; Rubin J; Guldberg RE; Wong K; Wang L; Boyan BD
  • Simulated microgravity using the Random Positioning Machine inhibits differentiation and alters gene expression profiles of 2T3 preosteoblasts.
    Am J Physiol Cell Physiol Volume: 288 Page(s): C1211 - C1221
    06/01/2005 Authors: Pardo SJ; Patel MJ; Sykes MC; Platt MO; Boyd NL; Sorescu GP; Xu M; van Loon JJWA; Wang MD; Jo H
  • Laminar shear stress decreases elastase activity of endothelial cells by inhibiting cathepsin K activity
    Volume: 19 Page(s): A1064 - A1064
    03/07/2005 Authors: Platt MO; Delgado-Reyes C; Ankeny R; Shin W; Song H; Jo H
  • PKA-Gene transfection in coronary microvessels increases endothelial NO production and eNOS phosphorylation
    Volume: 19 Page(s): A1242 - A1242
    03/07/2005 Authors: Wang H; Edwards J; Liu H; Jo H; Kaley G; Hintze T; Zhang XP
  • Peroxiredoxins (PRX) are upregulated by laminar shear stress in endothelial gells - Implications of PRX as mechanosensitive antioxidants in a subcellular-specific manner
    Volume: 39 Page(s): S75 - S76
    01/01/2005 Authors: Mowbray AL; Kang SW; Jo H
  • Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a Nox1-based NADPH oxidase
    CIRCULATION Volume: 110 Page(s): 90 - 90
    10/26/2004 Authors: Sorescu GP; Tressel SL; Song H; Hwang J; Dikalov S; Smith DA; Boyd NL; Platt MO; Lassegue B; Griendling KK
  • Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase.
    Circ Res Volume: 95 Page(s): 773 - 779
    10/15/2004 Authors: Sorescu GP; Song H; Tressel SL; Hwang J; Dikalov S; Smith DA; Boyd NL; Platt MO; Lassgue B; Griendling KK
  • Oscillatory shear stress (OS) upregulates cathepsin expression while inhibiting cystatin C expression in endothelial cells (EC) - Implication in atherosclerosis
    Volume: 18 Page(s): A1114 - A1114
    03/24/2004 Authors: Platt MO; Ankeny R; Shin WK; Sykes M; Jo H
  • Bone morphogenic protein 4 (BMP4) produced in endothelial cells (EC) by oscillatory shear (OS) induces monocyte adhesion by a redox sensitive manner
    Volume: 18 Page(s): A388 - A388
    03/23/2004 Authors: Sorescu GP; Hwang JN; Dikalov SI; Smith DA; Tressel SL; Jo HJ
  • Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a NOX1-based NADPH oxidase
    Volume: 37 Page(s): S65 - S65
    01/01/2004 Authors: Sorescu G; Song H; Tressel S; Platt M; Smith D; Jo HJ
  • Bovine caveolin-2 cloning and effects of shear stress on its localization in bovine aortic endothelial cells.
    Endothelium Volume: 11 Page(s): 189 - 198
    01/01/2004 Authors: Boyd N; Park H; Sun W-P; Coleman S; Cherukuri R; Jo H
  • A role for PYK2 in ANG II-dependent regulation of the PHAS-1-eIF4E complex by multiple signaling cascades in vascular smooth muscle.
    Am J Physiol Cell Physiol Volume: 285 Page(s): C1437 - C1444
    12/01/2003 Authors: Rocic P; Jo H; Lucchesi PA
  • Role of xanthine oxidoreductase and NAD(P)H oxidase in endothelial superoxide production in response to oscillatory shear stress.
    Am J Physiol Heart Circ Physiol Volume: 285 Page(s): H2290 - H2297
    12/01/2003 Authors: McNally JS; Davis ME; Giddens DP; Saha A; Hwang J; Dikalov S; Jo H; Harrison DG
  • High glucose induced NF-kappaB DNA-binding activity in HAEC is maintained under low shear stress but inhibited under high shear stress: role of nitric oxide.
    Atherosclerosis Volume: 171 Page(s): 225 - 234
    12/01/2003 Authors: Mohan S; Hamuro M; Koyoma K; Sorescu GP; Jo H; Natarajan M
  • Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion.
    J Biol Chem Volume: 278 Page(s): 47291 - 47298
    11/21/2003 Authors: Hwang J; Saha A; Boo YC; Sorescu GP; McNally JS; Holland SM; Dikalov S; Giddens DP; Griendling KK; Harrison DG
  • Oscillatory shear stress stimulates endothelial cell production of superoxide from p47phox dependent NAD(P)H oxidases leading to monocyte adhesion
    CIRCULATION Volume: 108 Page(s): 201 - 201
    10/28/2003 Authors: Saha A; Hwang J; Boo YC; McNally JS; Harrison DG; Griendling KK; Dikalov S; Jo H
  • Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase.
    Free Radic Biol Med Volume: 35 Page(s): 729 - 741
    10/01/2003 Authors: Boo YC; Sorescu GP; Bauer PM; Fulton D; Kemp BE; Harrison DG; Sessa WC; Jo H
  • Chronic shear induces caveolae formation and alters ERK and Akt responses in endothelial cells.
    Am J Physiol Heart Circ Physiol Volume: 285 Page(s): H1113 - H1122
    09/01/2003 Authors: Boyd NL; Park H; Yi H; Boo YC; Sorescu GP; Sykes M; Jo H
  • Flow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases.
    Am J Physiol Cell Physiol Volume: 285 Page(s): C499 - C508
    09/01/2003 Authors: Boo YC; Jo H
  • Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response.
    J Biol Chem Volume: 278 Page(s): 31128 - 31135
    08/15/2003 Authors: Sorescu GP; Sykes M; Weiss D; Platt MO; Saha A; Hwang J; Boyd N; Boo YC; Vega JD; Taylor WR
  • Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress stimulates an inflammatory response: Implication in atherosclerosis
    Volume: 23 Page(s): A6 - A6
    05/01/2003 Authors: Sorescu GP; Sykes M; Weiss D; Platt MO; Hwang JN; Boyd NL; Boo YC; Vega JD; Taylor WR; Jo H
  • Isolation and in vitro functional characterization of primary murine aortic endothelial cell cultures
    Volume: 23 Page(s): A65 - A65
    05/01/2003 Authors: Magid R; Martinson D; Hwang J; Jo H; Galis ZS
  • Monocyte adhesion to aortic endothelial cells leads to contact-dependent increased matrix metalloproteinase-9 secretion
    Volume: 23 Page(s): A1 - A1
    05/01/2003 Authors: Lessner SM; Hwang J; Jo H; Galis ZS
  • Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric-oxide synthase.
    J Biol Chem Volume: 278 Page(s): 14841 - 14849
    04/25/2003 Authors: Bauer PM; Fulton D; Boo YC; Sorescu GP; Kemp BE; Jo H; Sessa WC
  • IkappaBalpha-dependent regulation of low-shear flow-induced NF-kappa B activity: role of nitric oxide.
    Am J Physiol Cell Physiol Volume: 284 Page(s): C1039 - C1047
    04/01/2003 Authors: Mohan S; Hamuro M; Sorescu GP; Koyoma K; Sprague EA; Jo H; Valente AJ; Prihoda TJ; Natarajan M
  • Bone morphogenic protein-4 (BMP4) induced by oscillatory shear (OS) mediates monocyte adhesion to endothelial cells (EC) - A novel role of BMP4 in inflammatory response and atherosclerosis
    Volume: 17 Page(s): A1353 - A1353
    03/17/2003 Authors: Sorescu GP; Sykes M; Weiss D; Platt MO; Boyd NL; Boo YC; Vega JD; Taylor WR; Jo H
  • Laminar shear (LSS) and oscillatory shear stress (OSS) differentially stimulate O2-production and monocyte adhesion by NADPH dependent mechanisms in mouse aortic endothelial cells (MAEC)
    Volume: 17 Page(s): A1356 - A1356
    03/17/2003 Authors: Saha A; Hwang JA; Boo Y; Jo H
  • Modulation of strain-mediated PAI-1 gene expression in vascular smooth muscle cells by cGMP-elevating agents: Role of protein kinase A
    Volume: 17 Page(s): A1354 - A1354
    03/17/2003 Authors: Agahterhani A; Whalin M; Boo YC; Jo H; Taylor WR
  • Phosphorylation of eNOS at Ser635 stimulates NO production in a Ca2+-independent manner
    Volume: 17 Page(s): A804 - A804
    03/17/2003 Authors: Boo YC; Sorescu GP; Bauer PM; Kemp BE; Harrison DG; Sessa WC; Jo H
  • Chronic shear exposure changes localization of caveolin-1, and caveolae in endothelial cells
    Volume: 17 Page(s): A48 - A48
    03/14/2003 Authors: Boyd NL; Coleman SE; Jo H
  • Optimization of isolation and functional characterization of primary murine aortic endothelial cells.
    Endothelium Volume: 10 Page(s): 103 - 109
    01/01/2003 Authors: Magid R; Martinson D; Hwang J; Jo H; Galis ZS
  • Oscillatory shear stress stimulates endothelial production of O2f{ from p47phox-dependent NAD(P)H oxidases leading to monocyte adhesion.
    Volume: 35 Page(s): S26 - S26
    01/01/2003 Authors: Hwang JN; Saha A; Boo YC; Sorescu G; Jo H
  • Role of NAD(P)H oxidase and xanthine oxidoreductase in ROS production under oscillatory shear
    Volume: 35 Page(s): S27 - S27
    01/01/2003 Authors: McNally J; Davis M; Saha A; Hwang JN; Jo H; Dikalov S; Harrison D
  • Bybone morphogenic protein 4 (BMP4) produced in endothelial cells (EC) by oscillatory shear (OS) induces monocyte adhesion by a redox sensitive manner.
    Volume: 35 Page(s): S57 - S57
    01/01/2003 Authors: Sorescu G; Hwang JN; Dikalov S; Jo H
  • NAD(P)H oxidase-derived hydrogen peroxide mediates endothelial nitric oxide production in response to angiotensin II.
    J Biol Chem Volume: 277 Page(s): 48311 - 48317
    12/13/2002 Authors: Cai H; Li Z; Dikalov S; Holland SM; Hwang J; Jo H; Dudley SC; Harrison DG
  • Shear stress stimulates phosphorylation of eNOS at Ser(635) by a protein kinase A-dependent mechanism.
    Am J Physiol Heart Circ Physiol Volume: 283 Page(s): H1819 - H1828
    11/01/2002 Authors: Boo YC; Hwang J; Sykes M; Michell BJ; Kemp BE; Lum H; Jo H
  • Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.
    Hypertension Volume: 40 Page(s): 511 - 515
    10/01/2002 Authors: Landmesser U; Cai H; Dikalov S; McCann L; Hwang J; Jo H; Holland SM; Harrison DG
  • Shear stress stimulates phosphorylation of eNOS at Ser(1179) by Akt-independent mechanisms in endothelial cells - Role of Protein Kinase A
    Volume: 16 Page(s): A852 - A852
    03/22/2002 Authors: Boo YC; Sorescu G; Boyd N; Shiojima I; Walsh K; Du J; Jo HJ; Coulter WH
  • Differential phosphorylation of eNOS at Ser(116), Thr(497), Ser(635) and Ser(1179) in response to mechanical and humoral stimuli in endothelial cells
    FASEB JOURNAL Volume: 16 Page(s): A853 - A853
    03/22/2002 Authors: Boo YC; Hwang J; Skyes M; Griendling K; Jo HJ; Coulter WH
  • Laminar shear stress stimulates O-2(-) production by the p47(phox)-NAD(P)H oxidase dependent mechanisms in mouse aortic endothelial cells (MAEC)
    Volume: 16 Page(s): A430 - A430
    03/20/2002 Authors: Hwang J; DuPont K; Moon SD; Jo HJ
  • Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A.
    J Biol Chem Volume: 277 Page(s): 3388 - 3396
    02/01/2002 Authors: Boo YC; Sorescu G; Boyd N; Shiojima I; Walsh K; Du J; Jo H
  • Activation of c-Jun N-terminal kinase and apoptosis in endothelial cells mediated by endogenous generation of hydrogen peroxide.
    Biol Chem Volume: 383 Page(s): 693 - 701
    01/01/2002 Authors: Ramachandran A; Moellering D; Go Y-M; Shiva S; Levonen A-L; Jo H; Patel RP; Parthasarathy S; Darley-Usmar VM
  • NAD(P)H oxidiase-derived hydrogen peroxide mediates endothelial nitric oxide production in response to angiotensin II
    Volume: 33 Page(s): S363 - S364
    01/01/2002 Authors: Cal H; Li ZM; Dikalov S; Hwang J; Jo H; Dudley S; Harrison D
  • Endothelial NOS-dependent activation of c-Jun NH(2)- terminal kinase by oxidized low-density lipoprotein.
    Am J Physiol Heart Circ Physiol Volume: 281 Page(s): H2705 - H2713
    12/01/2001 Authors: Go YM; Levonen AL; Moellering D; Ramachandran A; Patel RP; Jo H; Darley-Usmar VM
  • Protein kinase B/Akt activates c-Jun NH(2)-terminal kinase by increasing NO production in response to shear stress.
    J Appl Physiol (1985) Volume: 91 Page(s): 1574 - 1581
    10/01/2001 Authors: Go YM; Boo YC; Park H; Maland MC; Patel R; Pritchard KA; Fujio Y; Walsh K; Darley-Usmar V; Jo H
  • Fas-induced expression of chemokines in human glioma cells: involvement of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase.
    Cancer Res Volume: 61 Page(s): 3084 - 3091
    04/01/2001 Authors: Choi C; Xu X; Oh JW; Lee SJ; Gillespie GY; Park H; Jo H; Benveniste EN
  • Mechanisms of cell signaling by nitric oxide and peroxynitrite: from mitochondria to MAP kinases.
    Antioxid Redox Signal Volume: 3 Page(s): 215 - 229
    04/01/2001 Authors: Levonen AL; Patel RP; Brookes P; Go YM; Jo H; Parthasarathy S; Anderson PG; Darley-Usmar VM
  • Protein kinase A regulates phosphorylation of eNOS-Ser(1179) in response to fluid laminar shear stress
    FREE RADICAL BIOLOGY AND MEDICINE Volume: 31 Page(s): S52 - S52
    01/01/2001 Authors: Boo YC; Jo H; Coulter WH
  • Cell signaling by reactive nitrogen and oxygen species in atherosclerosis.
    Free Radic Biol Med Volume: 28 Page(s): 1780 - 1794
    06/15/2000 Authors: Patel RP; Moellering D; Murphy-Ullrich J; Jo H; Beckman JS; Darley-Usmar VM
  • Caveolin-1 regulates shear stress-dependent activation of extracellular signal-regulated kinase.
    Am J Physiol Heart Circ Physiol Volume: 278 Page(s): H1285 - H1293
    04/01/2000 Authors: Park H; Go YM; Darji R; Choi JW; Lisanti MP; Maland MC; Jo H
  • Akt/protein kinase B regulates flow-dependent activation of cJun N-terminal kinase by producing nitric oxide from endothelial nitric oxide synthase
    FASEB JOURNAL Volume: 14 Page(s): A403 - A403
    03/15/2000 Authors: Go YM; Boo Y; Park H; Maland MC; Patel R; Darley-Usmar V; Pritchard KA; Fujio Y; Walsh K; Jo H
  • Ceramide regulates shear stress-dependent JNK activation in endothelial cells
    FASEB JOURNAL Volume: 14 Page(s): A449 - A449
    03/15/2000 Authors: Maland MC; Park H; Go YM; Jo H
  • Fibronectin-dependent integrins regulate shear-dependent activation of ERK.
    FASEB JOURNAL Volume: 14 Page(s): A449 - A449
    03/15/2000 Authors: Park H; Go YM; Mitchell L; Maland MC; Jo H
  • Activation of mitogen-activated protein kinase pathways by cyclic GMP and cyclic GMP-dependent protein kinase in contractile vascular smooth muscle cells.
    J Biol Chem Volume: 274 Page(s): 34301 - 34309
    11/26/1999 Authors: Komalavilas P; Shah PK; Jo H; Lincoln TM
  • Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH(2)-terminal kinase.
    Am J Physiol Volume: 277 Page(s): H1647 - H1653
    10/01/1999 Authors: Go YM; Patel RP; Maland MC; Park H; Beckman JS; Darley-Usmar VM; Jo H
  • Biological aspects of reactive nitrogen species.
    Biochim Biophys Acta Volume: 1411 Page(s): 385 - 400
    05/05/1999 Authors: Patel RP; McAndrew J; Sellak H; White CR; Jo H; Freeman BA; Darley-Usmar VM
  • Effects of pyrrolidine dithiocarbamate on endothelial cells: protection against oxidative stress.
    Free Radic Biol Med Volume: 26 Page(s): 1138 - 1145
    05/01/1999 Authors: Moellering D; McAndrew J; Jo H; Darley-Usmar VM
  • The induction of GSH synthesis by nanomolar concentrations of NO in endothelial cells: a role for gamma-glutamylcysteine synthetase and gamma-glutamyl transpeptidase.
    FEBS Lett Volume: 448 Page(s): 292 - 296
    04/09/1999 Authors: Moellering D; Mc Andrew J; Patel RP; Forman HJ; Mulcahy RT; Jo H; Darley-Usmar VM
  • Caveolin (CAV)-1 selectively mediates activation of ERK, but not JNK, by shear stress.
    FASEB JOURNAL Volume: 13 Page(s): A1019 - A1019
    03/15/1999 Authors: Park H; Go Y; Darji R; Choi J; Maland MC; Jo H
  • Shear stress induces expression of 1-glutamylcysteine synthetase (GCS) genes.
    FASEB JOURNAL Volume: 13 Page(s): A129 - A129
    03/12/1999 Authors: McAndrew J; Moellering D; Maland MC; Patel R; Darley-Usmar V; Jo H
  • A critical appraisal of hydrogen peroxide and superoxide as signaling molecules using the JNK/SAPK map kinase pathway
    FREE RADICAL BIOLOGY AND MEDICINE Volume: 27 Page(s): S64 - S64
    01/01/1999 Authors: Moellering DR; Go YM; Maland MC; Patel RP; Jo H; Darley-Usmar VM
  • In vitro system to study role of blood flow on nitric oxide production and cell signaling in endothelial cells.
    Methods Enzymol Volume: 301 Page(s): 513 - 522
    01/01/1999 Authors: Go YM; Park H; Maland MC; Jo H
  • Plasma membrane cholesterol is a key molecule in shear stress-dependent activation of extracellular signal-regulated kinase.
    J Biol Chem Volume: 273 Page(s): 32304 - 32311
    11/27/1998 Authors: Park H; Go YM; St John PL; Maland MC; Lisanti MP; Abrahamson DR; Jo H
  • Phosphatidylinositol 3-kinase gamma mediates shear stress-dependent activation of JNK in endothelial cells.
    Am J Physiol Volume: 275 Page(s): H1898 - H1904
    11/01/1998 Authors: Go YM; Park H; Maland MC; Darley-Usmar VM; Stoyanov B; Wetzker R; Jo H
  • Nitric oxide-dependent induction of glutathione synthesis through increased expression of gamma-glutamylcysteine synthetase.
    Arch Biochem Biophys Volume: 358 Page(s): 74 - 82
    10/01/1998 Authors: Moellering D; McAndrew J; Patel RP; Cornwell T; Lincoln T; Cao X; Messina JL; Forman HJ; Jo H; Darley-Usmar VM
  • Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain.
    FEBS Lett Volume: 428 Page(s): 205 - 211
    05/29/1998 Authors: Engelman JA; Chu C; Lin A; Jo H; Ikezu T; Okamoto T; Kohtz DS; Lisanti MP
  • Evidence for peroxynitrite a signaling molecule: Activation of JNK by flow in endothelial cells.
    FREE RADICAL BIOLOGY AND MEDICINE Volume: 25 Page(s): S51 - S51
    01/01/1998 Authors: Jo H; Go YM; Maland M; Patel R; Park H; Darley-Usmar VM
  • A novel cellular mechanism for the antioxidant effects of the NF kappa B inhibitor pyrrolidine dithiocarbamate.
    FREE RADICAL BIOLOGY AND MEDICINE Volume: 25 Page(s): S15 - S15
    01/01/1998 Authors: Darley-Usmar VM; McAndrew J; Patel R; Moellering D; Jo H
  • Filipin inhibits shear stress-induced activation of extracellular signal-regulated kinase (ERK), but not N-terminal Jun kinase (JNK) in bovine aortic endothelial cells.
    MOLECULAR BIOLOGY OF THE CELL Volume: 8 Page(s): 1211 - 1211
    11/01/1997 Authors: Park H; Go Y; Maland M; Jo H
  • The interplay of nitric oxide and peroxynitrite with signal transduction pathways: implications for disease.
    Semin Perinatol Volume: 21 Page(s): 351 - 366
    10/01/1997 Authors: McAndrew J; Patel RP; Jo H; Cornwell T; Lincoln T; Moellering D; White CR; Matalon S; Darley-Usmar V
  • Nitric oxide, free radicals and cell signalling in cardiovascular disease.
    Volume: 25 Page(s): 925 - 929
    08/01/1997 Authors: Darley-Usmar VM; McAndrew J; Patel R; Moellering D; Lincoln TM; Jo H; Cornwell T; Digerness S; White CR
  • Differential effect of shear stress on extracellular signal-regulated kinase and N-terminal Jun kinase in endothelial cells. Gi2- and Gbeta/gamma-dependent signaling pathways.
    J Biol Chem Volume: 272 Page(s): 1395 - 1401
    01/10/1997 Authors: Jo H; Sipos K; Go YM; Law R; Rong J; McDonald JM
  • Stearate inhibition of breast cancer cell proliferation. A mechanism involving epidermal growth factor receptor and G-proteins.
    Am J Pathol Volume: 148 Page(s): 987 - 995
    03/01/1996 Authors: Wickramasinghe NS; Jo H; McDonald JM; Hardy RW
  • MULTIPLE GI-PROTEINS ARE COUPLED TO THE INSULIN-RECEPTOR IN RAT ADIPOCYTES
    Volume: 44 Page(s): A207 - A207
    05/01/1995 Authors: JO HJ; HARDY RW; WILLIAMS JP; MOORE MA; BYER SJ; MCDONALD JM
  • Tyrosine phosphorylation of phosphatase inhibitor 2.
    J Cell Biochem Volume: 57 Page(s): 415 - 422
    03/01/1995 Authors: Williams JP; Jo H; Hunnicutt RE; Brautigan DL; McDonald JM
  • Tyrosine-phosphorylated calmodulin has reduced biological activity.
    Arch Biochem Biophys Volume: 315 Page(s): 119 - 126
    11/15/1994 Authors: Williams JP; Jo H; Sacks DB; Crimmins DL; Thoma RS; Hunnicutt RE; Radding W; Sharma RK; McDonald JM
  • Role of G proteins in shear stress-mediated nitric oxide production by endothelial cells.
    Am J Physiol Volume: 267 Page(s): C753 - C758
    09/01/1994 Authors: Kuchan MJ; Jo H; Frangos JA
  • EPIDERMAL GROWTH-FACTOR RECEPTOR IS ASSOCIATED WITH A 41-KDA G-PROTEIN IN 2 BREAST-CANCER CELL-LINES
    FASEB JOURNAL Volume: 8 Page(s): A1433 - A1433
    04/19/1994 Authors: WICKRAMASINGHE NSMD; MCDONALD JM; JO H; WILLIFORD J; HARDY RW
  • Insulin stimulates association of a 41kDa G-protein (GIR41) with the insulin receptor.
    Biochem Biophys Res Commun Volume: 196 Page(s): 99 - 106
    10/15/1993 Authors: Jo H; Byer S; McDonald JM
  • An insulin receptor peptide (1135-1156) stimulates guanosine 5'-[gamma-thio]triphosphate binding to the 67 kDa G-protein associated with the insulin receptor.
    Biochem J Volume: 294 ( Pt 1) Page(s): 19 - 24
    08/15/1993 Authors: Jo H; Radding W; Anantharamaiah GM; McDonald JM
  • A PUTATIVE G-PROTEIN BINDING PEPTIDE DERIVED FROM THE AMINO-ACID-SEQUENCE OF THE INSULIN-RECEPTOR INCREASES GTP-GAMMA-S BINDING TO INSULIN-RECEPTOR ASSOCIATED G-PROTEINS AND INHIBITS INSULIN-RECEPTOR KINASE-ACTIVITY
    Volume: 42 Page(s): A2 - A2
    05/01/1993 Authors: JO HJ; MCDONALD JM
  • EFFECT OF INSULIN ON THE SUBCELLULAR-DISTRIBUTION OF GTP-BINDING PROTEINS IN RAT ADIPOCYTES
    Volume: 1035 Page(s): 243 - 247
    01/01/1993 Authors: CHA BY; JO HJ; LEE KW; SON HY; KANG SK; MCDONALD JM
  • Identification, partial purification, and characterization of two guanosine triphosphate-binding proteins associated with insulin receptors.
    Endocrinology Volume: 131 Page(s): 2855 - 2862
    12/01/1992 Authors: Jo H; Cha BY; Davis HW; McDonald JM
  • The effect of varying albumin concentration and hydrostatic pressure on hydraulic conductivity and albumin permeability of cultured endothelial monolayers.
    Microvasc Res Volume: 41 Page(s): 390 - 407
    05/01/1991 Authors: Dull RO; Jo H; Sill H; Hollis TM; Tarbell JM
  • PHOSPHOTYROSYL CALMODULIN (CAM-P) HAS INCREASED AFFINITY FOR CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE (PDE)
    FASEB JOURNAL Volume: 5 Page(s): A448 - A448
    03/11/1991 Authors: WILLIAMS J; JO H; MCDONALD JM
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