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Profile

George Wilmot MD/PhD

  • Department of Neurology
    Associate Professor
  • (404) 712-7348
  • gwilmot@emory.edu

Academic Appointment

  • Adjunct Assistant Professor, Department of Pediatrics, Emory University School of Medicine
  • Assistant Professor, Department of Neurology, Emory University School of Medicine

Education

Degrees

  • M.D./Ph.D. from University of Michigan Medical School and Rackham School of Graduate Studies
  • BA from Emory University

Research

Focus

  • The clinical assessment and treatment of ataxias. Development of measurement tools for ataxia and their application to long-term natural history studies of ataxic disorders.

Publications

  • Spinocerebellar Ataxia Progression Measured with the Patient-Reported Outcome Measure of Ataxia.
    Mov Disord
    03/04/2025 Authors: Burt AL; L'Italien G; Perlman SL; Rosenthal LS; Kuo S-H; Ashizawa T; Zesiewicz T; Dietiker C; Opal P; Duquette A
  • Sensitivity of Advanced Magnetic Resonance Imaging to Progression over SixMonths in Early Spinocerebellar Ataxia.
    Mov Disord Volume: 39 Page(s): 1856 - 1867
    10/01/2024 Authors: Rezende TJR; Petit E; Park YW; Tezenas du Montcel S; Joers JM; DuBois JM; Moore Arnold H; Povazan M; Banan G; Valabregue R
  • The Cerebellar Cognitive Affective/Schmahmann Syndrome Scale in Spinocerebellar Ataxias.
    Cerebellum Volume: 23 Page(s): 1411 - 1425
    08/01/2024 Authors: Selvadurai LP; Perlman SL; Ashizawa T; Wilmot GR; Onyike CU; Rosenthal LS; Shakkottai VG; Paulson HL; Subramony SH; Bushara KO
  • SARA captures disparate progression and responsiveness in spinocerebellar ataxias.
    J Neurol Volume: 271 Page(s): 3743 - 3753
    07/01/2024 Authors: Petit E; Schmitz-Hbsch T; Coarelli G; Jacobi H; Heinzmann A; Figueroa KP; Perlman SL; Gomez CM; Wilmot GR; Schmahmann JD
  • SCAview: an Intuitive Visual Approach to the Integrative Analysis of Clinical Data in Spinocerebellar Ataxias.
    Cerebellum Volume: 23 Page(s): 887 - 895
    06/01/2024 Authors: Uebachs M; Wegner P; Schaaf S; Kugai S; Jacobi H; Kuo S-H; Ashizawa T; Fluck J; EUROSCA study group; ESMI study group
  • Propensity matched comparison of omaveloxolone treatment to Friedreich ataxia natural history data.
    Ann Clin Transl Neurol Volume: 11 Page(s): 4 - 16
    01/01/2024 Authors: Lynch DR; Goldsberry A; Rummey C; Farmer J; Boesch S; Delatycki MB; Giunti P; Hoyle JC; Mariotti C; Mathews KD
  • The S-Factor, a New Measure of Disease Severity in Spinocerebellar Ataxia: Findings and Implications.
    Cerebellum Volume: 22 Page(s): 790 - 809
    10/01/2023 Authors: Selvadurai LP; Perlman SL; Wilmot GR; Subramony SH; Gomez CM; Ashizawa T; Paulson HL; Onyike CU; Rosenthal LS; Sair HI
  • Clinically Meaningful Magnetic Resonance Endpoints Sensitive to Preataxic Spinocerebellar Ataxia Types 1 and 3.
    Ann Neurol Volume: 93 Page(s): 686 - 701
    04/01/2023 Authors: Chandrasekaran J; Petit E; Park YW; du Montcel ST; Joers JM; Deelchand DK; Povaan M; Banan G; Valabregue R; Ehses P
  • Efficacy of Omaveloxolone in Friedreich's Ataxia: Delayed-Start Analysis of the MOXIe Extension.
    Mov Disord Volume: 38 Page(s): 313 - 320
    02/01/2023 Authors: Lynch DR; Chin MP; Boesch S; Delatycki MB; Giunti P; Goldsberry A; Hoyle JC; Mariotti C; Mathews KD; Nachbauer W
  • Clinical management guidelines for Friedreich ataxia: best practice in rare diseases.
    Orphanet J Rare Dis Volume: 17 Page(s): 415
    11/12/2022 Authors: Corben LA; Collins V; Milne S; Farmer J; Musheno A; Lynch D; Subramony S; Pandolfo M; Schulz JB; Lin K
  • Natural History of Friedreich Ataxia: Heterogeneity of Neurologic Progression and Consequences for Clinical Trial Design.
    Neurology Volume: 99 Page(s): e1499 - e1510
    10/03/2022 Authors: Rummey C; Corben LA; Delatycki M; Wilmot G; Subramony SH; Corti M; Bushara K; Duquette A; Gomez C; Hoyle JC
  • Gaze-holding and anti-GAD antibody: prototypic heterogeneous motor dysfunction in immune disease.
    Cerebellum Volume: 21 Page(s): 55 - 63
    02/01/2022 Authors: Theeranaew W; Wang F; Ghasia FF; Wilmot G; Shaikh AG
  • A non-synonymous single nucleotide polymorphism in SIRT6 predicts neurological severity in Friedreich ataxia.
    Front Mol Biosci Volume: 9 Page(s): 933788
    01/01/2022 Authors: Rodden LN; Rummey C; Dong YN; Lagedrost S; Regner S; Brocht A; Bushara K; Delatycki MB; Gomez CM; Mathews K
  • Body Mass Index and Height in the Friedreich Ataxia Clinical Outcome Measures Study.
    Neurol Genet Volume: 7 Page(s): e638
    12/01/2021 Authors: Patel M; McCormick A; Tamaroff J; Dunn J; Mitchell JA; Lin KY; Farmer J; Rummey C; Perlman SL; Delatycki MB
  • Scoliosis in Friedreich's ataxia: longitudinal characterization in a large heterogeneous cohort.
    Ann Clin Transl Neurol Volume: 8 Page(s): 1239 - 1250
    06/01/2021 Authors: Rummey C; Flynn JM; Corben LA; Delatycki MB; Wilmot G; Subramony SH; Bushara K; Duquette A; Gomez CM; Hoyle JC
  • Safety and Efficacy of Omaveloxolone in Friedreich Ataxia (MOXIe Study).
    Ann Neurol Volume: 89 Page(s): 212 - 225
    02/01/2021 Authors: Lynch DR; Chin MP; Delatycki MB; Subramony SH; Corti M; Hoyle JC; Boesch S; Nachbauer W; Mariotti C; Mathews KD
  • Dysphagia in spinocerebellar ataxias type 1, 2, 3 and 6.
    J Neurol Sci Volume: 415 Page(s): 116878
    08/15/2020 Authors: Yang C-Y; Lai R-Y; Amokrane N; Lin C-Y; Figueroa KP; Pulst SM; Perlman S; Wilmot G; Gomez CM; Schmahmann JD
  • Health related quality of life in Friedreich Ataxia in a large heterogeneous cohort.
    J Neurol Sci Volume: 410 Page(s): 116642
    03/15/2020 Authors: Xiong E; Lynch AE; Corben LA; Delatycki MB; Subramony SH; Bushara K; Gomez CM; Hoyle JC; Yoon G; Ravina B
  • The impact of ethnicity on the clinical presentations of spinocerebellar ataxia type 3.
    Parkinsonism Relat Disord Volume: 72 Page(s): 37 - 43
    03/01/2020 Authors: Gan S-R; Figueroa KP; Xu H-L; Perlman S; Wilmot G; Gomez CM; Schmahmann J; Paulson H; Shakkottai VG; Ying SH
  • Spinocerebellar Ataxia Patient Perceptions Regarding Reproductive Options.
    Mov Disord Clin Pract Volume: 7 Page(s): 37 - 44
    01/01/2020 Authors: Cahn S; Rosen A; Wilmot G
  • Determinants of motor restoration in the syndrome of anti-GAD antibody
    Volume: 405
    10/15/2019 Authors: Wang F; Wilmot G; Shaikh AG
  • Tremor in the Degenerative Cerebellum: Towards the Understanding of Brain Circuitry for Tremor.
    Cerebellum Volume: 18 Page(s): 519 - 526
    06/01/2019 Authors: Lai R-Y; Tomishon D; Figueroa KP; Pulst SM; Perlman S; Wilmot G; Gomez CM; Schmahmann JD; Paulson H; Shakkottai VG
  • Safety, pharmacodynamics, and potential benefit of omaveloxolone in Friedreich ataxia.
    Ann Clin Transl Neurol Volume: 6 Page(s): 15 - 26
    01/01/2019 Authors: Lynch DR; Farmer J; Hauser L; Blair IA; Wang QQ; Mesaros C; Snyder N; Boesch S; Chin M; Delatycki MB
  • Deep Brain Stimulation in Parkinson: Use of Kinematics to Study Impact of DBS on Gait
    Volume: 84 Page(s): S193 - S193
    10/01/2018 Authors: Tripathi R; Alexander G; Wilmot G; Miocinovic S; Buetefisch C; Aia P; Scorr L; Factor S
  • Longitudinal analysis of contrast acuity in Friedreich ataxia.
    Neurol Genet Volume: 4 Page(s): e250
    08/01/2018 Authors: Hamedani AG; Hauser LA; Perlman S; Mathews K; Wilmot GR; Zesiewicz T; Subramony SH; Ashizawa T; Delatycki MB; Brocht A
  • Impact of Mobility Device Use on Quality of Life in Children With Friedreich Ataxia.
    J Child Neurol Volume: 33 Page(s): 397 - 404
    05/01/2018 Authors: Ejaz R; Chen S; Isaacs CJ; Carnevale A; Wilson J; George K; Delatycki MB; Perlman SL; Mathews KD; Wilmot GR
  • Comprehensive systematic review summary: Treatment of cerebellar motor dysfunction and ataxia: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology.
    Neurology Volume: 90 Page(s): 464 - 471
    03/06/2018 Authors: Zesiewicz TA; Wilmot G; Kuo S-H; Perlman S; Greenstein PE; Ying SH; Ashizawa T; Subramony SH; Schmahmann JD; Figueroa KP
  • C9orf72 repeat expansions as genetic modifiers for depression in spinocerebellar ataxias.
    Mov Disord Volume: 33 Page(s): 497 - 498
    03/01/2018 Authors: Figueroa KP; Gan S-R; Perlman S; Wilmot G; Gomez CM; Schmahmann J; Paulson H; Shakkottai VG; Ying SH; Zesiewicz T
  • Dystonia and ataxia progression in spinocerebellar ataxias.
    Parkinsonism Relat Disord Volume: 45 Page(s): 75 - 80
    12/01/2017 Authors: Kuo P-H; Gan S-R; Wang J; Lo RY; Figueroa KP; Tomishon D; Pulst SM; Perlman S; Wilmot G; Gomez CM
  • Impact of diabetes in the Friedreich ataxia clinical outcome measures study.
    Ann Clin Transl Neurol Volume: 4 Page(s): 622 - 631
    09/01/2017 Authors: McCormick A; Farmer J; Perlman S; Delatycki M; Wilmot G; Matthews K; Yoon G; Hoyle C; Subramony SH; Zesiewicz T
  • The Initial Symptom and Motor Progression in Spinocerebellar Ataxias.
    Cerebellum Volume: 16 Page(s): 615 - 622
    06/01/2017 Authors: Luo L; Wang J; Lo RY; Figueroa KP; Pulst SM; Kuo P-H; Perlman S; Wilmot G; Gomez CM; Schmahmann J
  • Postural Tremor and Ataxia Progression in Spinocerebellar Ataxias.
    Tremor Other Hyperkinet Mov (N Y) Volume: 7 Page(s): 492
    01/01/2017 Authors: Gan S-R; Wang J; Figueroa KP; Pulst SM; Tomishon D; Lee D; Perlman S; Wilmot G; Gomez CM; Schmahmann J
  • Progression of Friedreich ataxia: quantitative characterization over 5 years.
    Ann Clin Transl Neurol Volume: 3 Page(s): 684 - 694
    09/01/2016 Authors: Patel M; Isaacs CJ; Seyer L; Brigatti K; Gelbard S; Strawser C; Foerster D; Shinnick J; Schadt K; Yiu EM
  • Comorbid Medical Conditions in Friedreich Ataxia: Association With Inflammatory Bowel Disease and Growth Hormone Deficiency.
    J Child Neurol Volume: 31 Page(s): 1161 - 1165
    08/01/2016 Authors: Shinnick JE; Schadt K; Strawser C; Wilcox N; Perlman SL; Wilmot GR; Gomez CM; Mathews KD; Yoon G; Zesiewicz T
  • Strabismus and Micro-Opsoclonus in Machado-Joseph Disease.
    Cerebellum Volume: 15 Page(s): 491 - 497
    08/01/2016 Authors: Ghasia FF; Wilmot G; Ahmed A; Shaikh AG
  • Opsoclonus in a patient with increased titers of anti-GAD antibody provides proof for the conductance-based model of saccadic oscillations.
    J Neurol Sci Volume: 362 Page(s): 169 - 173
    03/15/2016 Authors: Shaikh AG; Wilmot G
  • Depression and clinical progression in spinocerebellar ataxias.
    Parkinsonism Relat Disord Volume: 22 Page(s): 87 - 92
    01/01/2016 Authors: Lo RY; Figueroa KP; Pulst SM; Perlman S; Wilmot G; Gomez C; Schmahmann J; Paulson H; Shakkottai VG; Ying S
  • Emerging therapies in Friedreich's ataxia.
    Neurodegener Dis Manag Volume: 6 Page(s): 49 - 65
    01/01/2016 Authors: Aranca TV; Jones TM; Shaw JD; Staffetti JS; Ashizawa T; Kuo S-H; Fogel BL; Wilmot GR; Perlman SL; Onyike CU
  • Frataxin levels in peripheral tissue in Friedreich ataxia.
    Ann Clin Transl Neurol Volume: 2 Page(s): 831 - 842
    08/01/2015 Authors: Lazaropoulos M; Dong Y; Clark E; Greeley NR; Seyer LA; Brigatti KW; Christie C; Perlman SL; Wilmot GR; Gomez CM
  • Eye Movement Abnormalities in patients with Spinocerebellar ataxia 3/Machado-Joseph disease
    Volume: 56
    06/01/2015 Authors: Ghasia FF; Wilmot G; Ahmed A; Shaikh A
  • Clinical evaluation of eye movements in spinocerebellar ataxias: a prospective multicenter study.
    J Neuroophthalmol Volume: 35 Page(s): 16 - 21
    03/01/2015 Authors: Moscovich M; Okun MS; Favilla C; Figueroa KP; Pulst SM; Perlman S; Wilmot G; Gomez C; Schmahmann J; Paulson H
  • Coenzyme Q10 and spinocerebellar ataxias.
    Mov Disord Volume: 30 Page(s): 214 - 220
    02/01/2015 Authors: Lo RY; Figueroa KP; Pulst SM; Lin C-Y; Perlman S; Wilmot G; Gomez C; Schmahmann J; Paulson H; Shakkottai VG
  • Clinical characteristics of patients with spinocerebellar ataxias 1, 2, 3 and 6 in the US; a prospective observational study.
    Orphanet J Rare Dis Volume: 8 Page(s): 177
    11/13/2013 Authors: Ashizawa T; Figueroa KP; Perlman SL; Gomez CM; Wilmot GR; Schmahmann JD; Ying SH; Zesiewicz TA; Paulson HL; Shakkottai VG
  • Analysis of the visual system in Friedreich ataxia.
    J Neurol Volume: 260 Page(s): 2362 - 2369
    09/01/2013 Authors: Seyer LA; Galetta K; Wilson J; Sakai R; Perlman S; Mathews K; Wilmot GR; Gomez CM; Ravina B; Zesiewicz T
  • Movement Disorders in Autosomal Dominant Spinocerebellar Ataxias: A Prospective Multicenter NIH Cohort Study
    Volume: 80
    02/12/2013 Authors: Moscovich M; Okun M; Favilla C; Figueroa K; Pulst S; Perlman S; Wilmot G; Gomez C; Schmahmann J; Ying S
  • Friedreich ataxia clinical outcome measures: natural history evaluation in 410 participants.
    J Child Neurol Volume: 27 Page(s): 1152 - 1158
    09/01/2012 Authors: Regner SR; Wilcox NS; Friedman LS; Seyer LA; Schadt KA; Brigatti KW; Perlman S; Delatycki M; Wilmot GR; Gomez CM
  • Clinical Characteristics of Spinocerebellar Ataxias 1, 2, 3 and 6
    Volume: 78
    04/01/2012 Authors: Ashizawa T; Perlman S; Gomez C; Wilmot G; Schmahmann J; Ying S; Zesiewicz T; Paulson H; Shakkottai V; Bushara K
  • Prior Molecular Diagnostic Accuracy and Age of Disease Onset Variation in the CRC-SCA, a Multicenter Study of Spinocerebellar Ataxias
    Volume: 78
    04/01/2012 Authors: Figueroa K; Gomez C; Paulson H; Perlman S; Schmahmann J; Subramony S; Wilmot G; Zesiewicz T; Ashizawa T; Pulst S
  • FXN methylation predicts expression and clinical outcome in Friedreich ataxia.
    Ann Neurol Volume: 71 Page(s): 487 - 497
    04/01/2012 Authors: Evans-Galea MV; Carrodus N; Rowley SM; Corben LA; Tai G; Saffery R; Galati JC; Wong NC; Craig JM; Lynch DR
  • Analysis of echocardiograms in a large heterogeneous cohort of patients with friedreich ataxia.
    Am J Cardiol Volume: 109 Page(s): 401 - 405
    02/01/2012 Authors: Regner SR; Lagedrost SJ; Plappert T; Paulsen EK; Friedman LS; Snyder ML; Perlman SL; Mathews KD; Wilmot GR; Schadt KA
  • Other spinocerebellar ataxias.
    Handb Clin Neurol Volume: 103 Page(s): 581 - 586
    01/01/2012 Authors: Cloud LJ; Wilmot G
  • Mortality in Friedreich ataxia.
    J Neurol Sci Volume: 307 Page(s): 46 - 49
    08/15/2011 Authors: Tsou AY; Paulsen EK; Lagedrost SJ; Perlman SL; Mathews KD; Wilmot GR; Ravina B; Koeppen AH; Lynch DR
  • Therapeutic interventions in the primary hereditary ataxias.
    Curr Treat Options Neurol Volume: 12 Page(s): 257 - 273
    07/01/2010 Authors: Revuelta GJ; Wilmot GR
  • Measuring the rate of progression in Friedreich ataxia: implications for clinical trial design.
    Mov Disord Volume: 25 Page(s): 426 - 432
    03/15/2010 Authors: Friedman LS; Farmer JM; Perlman S; Wilmot G; Gomez CM; Bushara KO; Mathews KD; Subramony SH; Ashizawa T; Balcer LJ
  • A negative electroretinogram (ERG) in a case of probable multiple system atrophy (MSA).
    Doc Ophthalmol Volume: 118 Page(s): 247 - 256
    06/01/2009 Authors: Barnes CS; Yan J; Wilmot GR
  • Treatment of Spinocerebellar Ataxia and Fragile X-Associated Tremor Ataxia Syndrome (FXTAS) with Varenicline (Chantix (R)): Results of a Retrospective, Blinded Video Analysis
    Volume: 72 Page(s): A43 - A43
    03/17/2009 Authors: Zesiewicz T; Perlman S; Lynch D; Bushara K; Sullivan K; Wilmot G; Ashizatva T; Subramony S; Gomez C
  • Health related quality of life measures in Friedreich Ataxia.
    J Neurol Sci Volume: 272 Page(s): 123 - 128
    09/15/2008 Authors: Epstein E; Farmer JM; Tsou A; Perlman S; Subramony SH; Gomez CM; Ashizawa T; Wilmot GR; Mathews K; Wilson RB
  • Antioxidant use in Friedreich ataxia.
    J Neurol Sci Volume: 267 Page(s): 174 - 176
    04/15/2008 Authors: Myers L; Farmer JM; Wilson RB; Friedman L; Tsou A; Perlman SL; Subramony SH; Gomez CM; Ashizawa T; Wilmot GR
  • Measuring Friedreich ataxia: complementary features of examination and performance measures.
    Neurology Volume: 66 Page(s): 1711 - 1716
    06/13/2006 Authors: Lynch DR; Farmer JM; Tsou AY; Perlman S; Subramony SH; Gomez CM; Ashizawa T; Wilmot GR; Wilson RB; Balcer LJ
  • Spinocerebellar ataxia type 2 with isolated levodopa-responsive leg tremor in the setting of typical ataxic syndrome
    Volume: 21 Page(s): S334 - S334
    01/01/2006 Authors: Esper CD; Wilmot GR; Delong MR
  • Validation of clinical outcome measures in Friedreich ataxia
    Volume: 64 Page(s): A58 - A59
    03/22/2005 Authors: Lynch DR; Farmer JM; Tsou AY; Perlman SL; Subramony SH; Gomez C; Ashizawa T; Wilmot GR; Balcer LJ
  • Health related quality of life in Friedreich ataxia
    Volume: 64 Page(s): A59 - A59
    03/22/2005 Authors: Tsou AY; Farmer JM; Perlman SL; Subramony SH; Gomez C; Ashizawa T; Wilmot GR; Balcer LJ; Lynch DR
  • Very late onset Friedreich's ataxia with a 25-year clinical course and hemizygous trinucleotide expansion.
    Volume: 62 Page(s): 557 - 557
    05/01/2003 Authors: Castellano-Sanchez AA; Hunter SB; Gearing M; Brat DJ; Wilmot G; Koeppen AH
  • Protein-protein interactions of Ube4b/NMNAT, a gene responsible for slow Wallerian degeneration
    Volume: 54 Page(s): S51 - S51
    01/01/2003 Authors: Torre ER; Li B; Wilmot GR
  • Immunofluorescent staining for emerin in hair roots distinguishes Emery-Dreifuss muscular dystrophy patients and carriers from normal individuals.
    AMERICAN JOURNAL OF HUMAN GENETICS Volume: 65 Page(s): A413 - A413
    10/01/1999 Authors: Wilmot GR; Warren ST
  • gRICH68 and gRICH70 are 2',3'-cyclic-nucleotide 3'-phosphodiesterases induced during goldfish optic nerve regeneration.
    J Biol Chem Volume: 272 Page(s): 11479 - 11486
    04/25/1997 Authors: Ballestero RP; Wilmot GR; Agranoff BW; Uhler MD
  • Motor neuron disease with parkinsonism.
    Arch Neurol Volume: 53 Page(s): 987 - 991
    10/01/1996 Authors: Qureshi AI; Wilmot G; Dihenia B; Schneider JA; Krendel DA
  • Isolation of cDNA clones encoding RICH: a protein induced during goldfish optic nerve regeneration with homology to mammalian 2',3'-cyclic-nucleotide 3'-phosphodiesterases.
    Proc Natl Acad Sci U S A Volume: 92 Page(s): 8621 - 8625
    09/12/1995 Authors: Ballestero RP; Wilmot GR; Leski ML; Uhler MD; Agranoff BW
  • The expression of the protein p68/70 within the goldfish visual system suggests a role in both regeneration and neurogenesis.
    J Neurosci Volume: 13 Page(s): 387 - 401
    01/01/1993 Authors: Wilmot GR; Raymond PA; Agranoff BW
  • Glutamic acid-insensitive [3H]kainic acid binding in goldfish brain.
    Brain Res Volume: 571 Page(s): 73 - 78
    01/31/1992 Authors: Davis RE; Wilmot GR; Cha JH
  • COINCIDENCES AMONG THE MARYLAND AND ROME GRAVITATIONAL-WAVE DETECTOR DATA AND THE MONT BLANC AND KAMIOKA NEUTRINO DETECTOR DATA IN THE PERIOD OF SN1987A
    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES Volume: 571 Page(s): 561 - 576
    12/05/1989 Authors: AMALDI E; BASSAN M; BONIFAZI P; CASTELLANO MG; COCCIA E; COSMELLI C; FRASCA S; GRETZ D; MODENA I; PALLOTTINO GV
  • RELEASE OF GLUTAMATE FROM PURIFIED BOVINE SYNAPTIC VESICLES
    Volume: 34 Page(s): 1011 - 1011
    10/01/1986 Authors: WILMOT GR; UEDA T
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