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Profile

Gianluca Tosini

  • Department of Ophthalmology
    Adjunct Professor
  • gianluca.tosini@emory.edu

Research

Publications

  • From Pineal to Biological Rhythms Through Melatonin.
    J Pineal Res Volume: 77 Page(s): e70044
    03/01/2025 Authors: Korf H-W; Tosini G
  • Disruption of Melatonin Signaling Leads to Lipids Accumulation in the Liver of Melatonin Proficient Mice.
    J Pineal Res Volume: 76 Page(s): e70007
    11/01/2024 Authors: Goyal V; Tosini G
  • Environmental circadian disruption re-writes liver circadian proteomes.
    Nat Commun Volume: 15 Page(s): 5537
    07/01/2024 Authors: Duong HA; Baba K; DeBruyne JP; Davidson AJ; Ehlen C; Powell M; Tosini G
  • Melatonin in the mammalian retina: Synthesis, mechanisms of action and neuroprotection.
    J Pineal Res Volume: 76 Page(s): e12951
    04/01/2024 Authors: Felder-Schmittbuhl MP; Hicks D; Ribelayga CP; Tosini G
  • "The ubiquitin ligase SIAH2 is a female-specific regulator of circadian rhythms and metabolism".
    PLoS Genet Volume: 18 Page(s): e1010305
    07/01/2022 Authors: Mekbib T; Suen T-C; Rollins-Hairston A; Smith K; Armstrong A; Gray C; Owino S; Baba K; Baggs JE; Ehlen JC
  • The Circadian Clock in the Retinal Pigment Epithelium Controls the Diurnal Rhythm of Phagocytic Activity.
    Int J Mol Sci Volume: 23
    05/10/2022 Authors: DeVera C; Dixon J; Chrenek MA; Baba K; Le YZ; Iuvone PM; Tosini G
  • Blue-light-blocking Lenses in Eyeglasses: A Question of Timing.
    Optom Vis Sci Volume: 99 Page(s): 228 - 229
    03/01/2022 Authors: Tosini G
  • Circadian Regulation of Retinal Pigment Epithelium Function.
    Int J Mol Sci Volume: 23
    02/28/2022 Authors: Baba K; Goyal V; Tosini G
  • The circadian clock mediates the response to oxidative stress in a cone photoreceptorlike (661W) cell line via regulation of glutathione peroxidase activity.
    F1000Res Volume: 11 Page(s): 1072
    01/01/2022 Authors: Baba K; Suen T-C; Goyal V; Stowie A; Davidson A; DeBruyne J; Tosini G
  • Assessing the Role of Melatonin in the Modulation of Visual Functions in the Mouse.
    Methods Mol Biol Volume: 2550 Page(s): 377 - 389
    01/01/2022 Authors: Baba K; Tosini G
  • Real-Time Monitoring of Circadian Rhythms in the Eye.
    Methods Mol Biol Volume: 2550 Page(s): 367 - 375
    01/01/2022 Authors: Baba K; Tosini G
  • Association between MTNR1B polymorphisms and obesity in African American: findings from the Jackson Heart Study.
    BMC Med Genomics Volume: 14 Page(s): 136
    05/21/2021 Authors: Tchio C; Musani SK; Quarshie A; Tosini G
  • Obituary: Michael Menaker, PhD. (1934-2021).
    J Pineal Res Volume: 70 Page(s): e12729
    05/01/2021 Authors: Cassone VM; Tosini G
  • Photoreceptor Degeneration in Homozygous Male Per2luc Mice During Aging.
    J Biol Rhythms Volume: 36 Page(s): 137 - 145
    04/01/2021 Authors: Goyal V; DeVera C; Baba K; Sellers J; Chrenek MA; Iuvone PM; Tosini G
  • Removal of melatonin receptor type 1 signalling induces dyslipidaemia and hormonal changes in mice subjected to environmental circadian disruption.
    Endocrinol Diabetes Metab Volume: 4 Page(s): e00171
    01/01/2021 Authors: Tchio C; Baba K; Piccione G; Tosini G
  • Circadian rhythms and obesity: Timekeeping governs lipid metabolism.
    J Pineal Res Volume: 69 Page(s): e12682
    10/01/2020 Authors: Li Y; Ma J; Yao K; Su W; Tan B; Wu X; Huang X; Li T; Yin Y; Tosini G
  • Administration of Exogenous Melatonin Improves the Diurnal Rhythms of the Gut Microbiota in Mice Fed a High-Fat Diet.
    mSystems Volume: 5
    05/19/2020 Authors: Yin J; Li Y; Han H; Ma J; Liu G; Wu X; Huang X; Fang R; Baba K; Bin P
  • Dopamine 2 Receptor Signaling Controls the Daily Burst in Phagocytic Activity in the Mouse Retinal Pigment Epithelium.
    Invest Ophthalmol Vis Sci Volume: 61 Page(s): 10
    05/11/2020 Authors: Goyal V; DeVera C; Laurent V; Sellers J; Chrenek MA; Hicks D; Baba K; Iuvone PM; Tosini G
  • Circadian analysis of the mouse retinal pigment epithelium transcriptome.
    Exp Eye Res Volume: 193 Page(s): 107988
    04/01/2020 Authors: DeVera C; Tosini G
  • Removing melatonin receptor type 1 signaling leads to selective leptin resistance in the arcuate nucleus.
    J Pineal Res Volume: 67 Page(s): e12580
    09/01/2019 Authors: Buonfiglio D; Tchio C; Furigo I; Donato J; Baba K; Cipolla-Neto J; Tosini G
  • Retinal Circadian Clocks are Major Players in the Modulation of Retinal Functions and Photoreceptor Viability.
    Yale J Biol Med Volume: 92 Page(s): 233 - 240
    06/01/2019 Authors: DeVera C; Baba K; Tosini G
  • Melatonin modulates daytime-dependent synaptic plasticity and learning efficiency.
    J Pineal Res Volume: 66 Page(s): e12553
    04/01/2019 Authors: Jilg A; Bechstein P; Saade A; Dick M; Li TX; Tosini G; Rami A; Zemmar A; Stehle JH
  • Melatonin Signaling a Key Regulator of Glucose Homeostasis and Energy Metabolism.
    Front Endocrinol (Lausanne) Volume: 10 Page(s): 488
    01/01/2019 Authors: Owino S; Buonfiglio DDC; Tchio C; Tosini G
  • Melatonin receptor heterodimerization in a photoreceptor-like cell line endogenously expressing melatonin receptors.
    Mol Vis Volume: 25 Page(s): 791 - 799
    01/01/2019 Authors: Snchez-Bretao A; Suen T-C; Baba K; DeBruyne J; Tosini G
  • Removal of clock gene Bmal1 from the retina affects retinal development and accelerates cone photoreceptor degeneration during aging.
    Proc Natl Acad Sci U S A Volume: 115 Page(s): 13099 - 13104
    12/18/2018 Authors: Baba K; Piano I; Lyuboslavsky P; Chrenek MA; Sellers JT; Zhang S; Gargini C; He L; Tosini G; Iuvone PM
  • Heteromeric MT1/MT2 melatonin receptors modulate the scotopic electroretinogram via PKC in mice.
    Exp Eye Res Volume: 177 Page(s): 50 - 54
    12/01/2018 Authors: Piano I; Baba K; Claudia Gargini; Tosini G
  • Ocular Clocks: Adapting Mechanisms for Eye Functions and Health.
    Invest Ophthalmol Vis Sci Volume: 59 Page(s): 4856 - 4870
    10/01/2018 Authors: Felder-Schmittbuhl M-P; Buhr ED; Dkhissi-Benyahya O; Hicks D; Peirson SN; Ribelayga CP; Sandu C; Spessert R; Tosini G
  • Aging Alters Circadian Rhythms in the Mouse Eye.
    J Biol Rhythms Volume: 33 Page(s): 441 - 445
    08/01/2018 Authors: Baba K; Tosini G
  • Removal of the clock gene Bmal1 from 661W cells affects cell viability and response to oxidative stress
    Volume: 59
    07/01/2018 Authors: Baba K; Suen T-C; Sanchez-Bretano A; DeBruyne J; Iuvone PM; Tosini G
  • Effect of Melatonin on Photoreceptor Survival
    Volume: 59
    07/01/2018 Authors: Tosini G
  • Consequences of circadian clock disruption in the retina
    Volume: 59
    07/01/2018 Authors: Zhang S; Lyuboslavsky P; Chrenek MA; Piano I; Baba K; Tosini G; Iuvone PM
  • Circadian and dopamine modulation of sensitivity to light-induced retinal degeneration (LIRD) in mice
    Volume: 59
    07/01/2018 Authors: Lyuboslavsky P; Sellers JT; Tosini G; Iuvone PM
  • Melatonin Receptor Heterodimers formation and signaling in 661 W cells
    Volume: 59
    07/01/2018 Authors: Sanchez-Bretano A; Suen T-C; Baba K; DeBruyne J; Tosini G
  • Nocturnal activation of melatonin receptor type 1 signaling modulates diurnal insulin sensitivity via regulation of PI3K activity.
    J Pineal Res Volume: 64
    04/01/2018 Authors: Owino S; Snchez-Bretao A; Tchio C; Cecon E; Karamitri A; Dam J; Jockers R; Piccione G; Noh HL; Kim T
  • The Retinal Circadian Clock and Photoreceptor Viability.
    Adv Exp Med Biol Volume: 1074 Page(s): 345 - 350
    01/01/2018 Authors: Baba K; Ribelayga CP; Michael Iuvone P; Tosini G
  • Melatonin signaling affects the timing in the daily rhythm of phagocytic activity by the retinal pigment epithelium.
    Exp Eye Res Volume: 165 Page(s): 90 - 95
    12/01/2017 Authors: Laurent V; Sengupta A; Snchez-Bretao A; Hicks D; Tosini G
  • Dopamine 2 Receptor Activation Entrains Circadian Clocks in Mouse Retinal Pigment Epithelium.
    Sci Rep Volume: 7 Page(s): 5103
    07/11/2017 Authors: Baba K; DeBruyne JP; Tosini G
  • Melatonin protects 661W cells from cell death induced by H2O2 via inhibition of the Fas/FasL-Caspase 3 pathway
    Volume: 58
    06/01/2017 Authors: Sanchez-Bretano A; Janjua U; Piano I; Gargini G; Baba K; Tosini G
  • Retinal circadian clock modulates cone photoreceptor viability in mice
    Volume: 58
    06/01/2017 Authors: Baba K; Piano I; Gargini G; Luvone PM; Tosini G
  • Heteromeric MT1/MT2 Melatonin Receptors Signal Via PKC-zeta in Mouse Photoreceptors
    Volume: 58
    06/01/2017 Authors: Tosini G; Piano I; Gargini G; Baba K
  • Melatonin partially protects 661W cells from H2O2-induced death by inhibiting Fas/FasL-caspase-3.
    Mol Vis Volume: 23 Page(s): 844 - 852
    01/01/2017 Authors: Snchez-Bretao A; Baba K; Janjua U; Piano I; Gargini C; Tosini G
  • Gnaz couples the circadian and dopaminergic system to G protein-mediated signaling in mouse photoreceptors.
    PLoS One Volume: 12 Page(s): e0187411
    01/01/2017 Authors: Vancura P; Abdelhadi S; Csicsely E; Baba K; Tosini G; Iuvone PM; Spessert R
  • Circadian Rhythm in Cone-like (661W) Photoreceptor Cells
    Volume: 57
    09/01/2016 Authors: Baba K; Tubo T; Suen T-C; DeBruyne J; Tosini G
  • Dopamine 2 Receptor Signaling Controls the Daily Burst in Phagocytic Activity by the Retinal Pigment Epithelium.
    Volume: 57
    09/01/2016 Authors: Tosini G; Baba K; Laurent V; Hicks D
  • Update on melatonin receptors: IUPHAR Review 20.
    Br J Pharmacol Volume: 173 Page(s): 2702 - 2725
    09/01/2016 Authors: Jockers R; Delagrange P; Dubocovich ML; Markus RP; Renault N; Tosini G; Cecon E; Zlotos DP
  • Circadian and Dopaminergic Regulation of Fatty Acid Oxidation Pathway Genes in Retina and Photoreceptor Cells.
    PLoS One Volume: 11 Page(s): e0164665
    01/01/2016 Authors: Vancura P; Wolloscheck T; Baba K; Tosini G; Iuvone PM; Spessert R
  • Effects of blue light on the circadian system and eye physiology.
    Mol Vis Volume: 22 Page(s): 61 - 72
    01/01/2016 Authors: Tosini G; Ferguson I; Tsubota K
  • Melatonin Signaling Controls the Daily Rhythm in Blood Glucose Levels Independent of Peripheral Clocks.
    PLoS One Volume: 11 Page(s): e0148214
    01/01/2016 Authors: Owino S; Contreras-Alcantara S; Baba K; Tosini G
  • Cone Viability Is Affected by Disruption of Melatonin Receptors Signaling.
    Invest Ophthalmol Vis Sci Volume: 57 Page(s): 94 - 104
    01/01/2016 Authors: Gianesini C; Hiragaki S; Laurent V; Hicks D; Tosini G
  • Pgc-1 and Nr4a1 Are Target Genes of Circadian Melatonin and Dopamine Release in Murine Retina.
    Invest Ophthalmol Vis Sci Volume: 56 Page(s): 6084 - 6094
    09/01/2015 Authors: Kunst S; Wolloscheck T; Kelleher DK; Wolfrum U; Sargsyan SA; Iuvone PM; Baba K; Tosini G; Spessert R
  • Unique Regulation of the Melatonin Synthetic Pathway in the Retina of Diurnal Female Arvicanthis ansorgei (Rodentia).
    Endocrinology Volume: 156 Page(s): 3292 - 3308
    09/01/2015 Authors: Gianesini C; Clesse D; Tosini G; Hicks D; Laurent V
  • Melatonin Entrains PER2::LUC Bioluminescence Circadian Rhythm in the Mouse Cornea.
    Invest Ophthalmol Vis Sci Volume: 56 Page(s): 4753 - 4758
    07/01/2015 Authors: Baba K; Davidson AJ; Tosini G
  • Shell neurons of the master circadian clock coordinate the phase of tissue clocks throughout the brain and body.
    BMC Biol Volume: 13 Page(s): 43
    06/23/2015 Authors: Evans JA; Suen T-C; Callif BL; Mitchell AS; Castanon-Cervantes O; Baker KM; Kloehn I; Baba K; Teubner BJW; Ehlen JC
  • Cones Viability is Affected by Removal of Melatonin Signaling
    Volume: 56
    06/01/2015 Authors: Tosini G; Gianesini C; Hiragaki S; Laurent V; Hicks D
  • Novel regulation of melatonin synthesis by cones and ganglion cells in the retina of a diurnal rodent Arvicanthis ansorgei
    Volume: 56
    06/01/2015 Authors: Gianesini C; Hennequin D; Clesse D; Tosini G; Hicks D; Laurent V
  • Understanding melatonin receptor pharmacology: latest insights from mouse models, and their relevance to human disease.
    Bioessays Volume: 36 Page(s): 778 - 787
    08/01/2014 Authors: Tosini G; Owino S; Guillaume J-L; Jockers R
  • Regulation of Ocular Functions by Dopamine and Melatonin
    Volume: 55
    04/01/2014 Authors: Tosini G; Baba K
  • Circadian organization of the mammalian retina: from gene regulation to physiology and diseases.
    Prog Retin Eye Res Volume: 39 Page(s): 58 - 76
    03/01/2014 Authors: McMahon DG; Iuvone PM; Tosini G
  • N-acetylserotonin: circadian activation of the BDNF receptor and neuroprotection in the retina and brain.
    Adv Exp Med Biol Volume: 801 Page(s): 765 - 771
    01/01/2014 Authors: Iuvone PM; Boatright JH; Tosini G; Ye K
  • Melatonin signaling modulates clock genes expression in the mouse retina.
    PLoS One Volume: 9 Page(s): e106819
    01/01/2014 Authors: Hiragaki S; Baba K; Coulson E; Kunst S; Spessert R; Tosini G
  • Heteromeric MT1/MT2 melatonin receptors modulate photoreceptor function.
    Sci Signal Volume: 6 Page(s): ra89
    10/08/2013 Authors: Baba K; Benleulmi-Chaachoua A; Journ A-S; Kamal M; Guillaume J-L; Dussaud S; Gbahou F; Yettou K; Liu C; Contreras-Alcantara S
  • Modulation of the Daily Rhythm in Disc Shedding by Melatonin in the Mouse
    Volume: 54
    06/01/2013 Authors: Tosini G; Laurent V; Baba K; Hiragaki S; Contreras-Alcantara S; Hicks D
  • Dopamine Entrains The Circadian Rhythm of PER2::LUC Bioluminescence in The Mouse Retinal Pigment Epithelium
    Volume: 54
    06/01/2013 Authors: Baba K; Contreras-Alcantara S; Tosini G
  • Melatonin receptor agonist-induced reduction of SNP-released nitric oxide and cGMP production in isolated human non-pigmented ciliary epithelial cells.
    Exp Eye Res Volume: 107 Page(s): 1 - 10
    02/01/2013 Authors: Dortch-Carnes J; Tosini G
  • Is the melatonin receptor type 1 involved in the pathogenesis of glaucoma?
    J Glaucoma Volume: 22 Suppl 5 Page(s): S49 - S50
    01/01/2013 Authors: Tosini G; Iuvone M; Boatright JH
  • N-acetylserotonin: neuroprotection, neurogenesis, and the sleepy brain.
    Neuroscientist Volume: 18 Page(s): 645 - 653
    12/01/2012 Authors: Tosini G; Ye K; Iuvone PM
  • Melatonin: an underappreciated player in retinal physiology and pathophysiology.
    Exp Eye Res Volume: 103 Page(s): 82 - 89
    10/01/2012 Authors: Tosini G; Baba K; Hwang CK; Iuvone PM
  • GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness.
    Am J Hum Genet Volume: 90 Page(s): 331 - 339
    02/10/2012 Authors: Peachey NS; Ray TA; Florijn R; Rowe LB; Sjoerdsma T; Contreras-Alcantara S; Baba K; Tosini G; Pozdeyev N; Iuvone PM
  • Age-related changes in the daily rhythm of photoreceptor functioning and circuitry in a melatonin-proficient mouse strain.
    PLoS One Volume: 7 Page(s): e37799
    01/01/2012 Authors: Baba K; Mazzoni F; Owino S; Contreras-Alcantara S; Strettoi E; Tosini G
  • N-acetylserotonin promotes hippocampal neuroprogenitor cell proliferation in sleep-deprived mice.
    Proc Natl Acad Sci U S A Volume: 108 Page(s): 8844 - 8849
    05/24/2011 Authors: Sompol P; Liu X; Baba K; Paul KN; Tosini G; Iuvone PM; Ye K
  • Removal of melatonin receptor type 1 increases intraocular pressure and retinal ganglion cells death in the mouse.
    Neurosci Lett Volume: 494 Page(s): 61 - 64
    04/20/2011 Authors: Alcantara-Contreras S; Baba K; Tosini G
  • Localization of melatonin receptor 1 in mouse retina and its role in the circadian regulation of the electroretinogram and dopamine levels.
    PLoS One Volume: 6 Page(s): e24483
    01/01/2011 Authors: Sengupta A; Baba K; Mazzoni F; Pozdeyev NV; Strettoi E; Iuvone PM; Tosini G
  • Circadian regulation of the PERIOD 2::LUCIFERASE bioluminescence rhythm in the mouse retinal pigment epithelium-choroid.
    Mol Vis Volume: 16 Page(s): 2605 - 2611
    12/07/2010 Authors: Baba K; Sengupta A; Tosini M; Contreras-Alcantara S; Tosini G
  • Removal of melatonin receptor type 1 induces insulin resistance in the mouse.
    Obesity (Silver Spring) Volume: 18 Page(s): 1861 - 1863
    09/01/2010 Authors: Contreras-Alcantara S; Baba K; Tosini G
  • Chronic sleep deprivation markedly reduces coagulation factor VII expression.
    Haematologica Volume: 95 Page(s): 1429 - 1432
    08/01/2010 Authors: Pinotti M; Bertolucci C; Frigato E; Branchini A; Cavallari N; Baba K; Contreras-Alcantara S; Ehlen JC; Bernardi F; Paul KN
  • Removal of Melatonin Receptor Type 1 Increases Intraocular Pressure and Retinal Ganglion Cells Death in the Mouse
    Volume: 51
    04/01/2010 Authors: Tosini G; Alcantara-Contreras S; Sengupta A; Baba K
  • N-acetylserotonin activates TrkB receptor in a circadian rhythm.
    Proc Natl Acad Sci U S A Volume: 107 Page(s): 3876 - 3881
    02/23/2010 Authors: Jang S-W; Liu X; Pradoldej S; Tosini G; Chang Q; Iuvone PM; Ye K
  • The role of retinal photoreceptors in the regulation of circadian rhythms.
    Rev Endocr Metab Disord Volume: 10 Page(s): 271 - 278
    12/01/2009 Authors: Paul KN; Saafir TB; Tosini G
  • Melatonin modulates visual function and cell viability in the mouse retina via the MT1 melatonin receptor.
    Proc Natl Acad Sci U S A Volume: 106 Page(s): 15043 - 15048
    09/01/2009 Authors: Baba K; Pozdeyev N; Mazzoni F; Contreras-Alcantara S; Liu C; Kasamatsu M; Martinez-Merlos T; Strettoi E; Iuvone PM; Tosini G
  • The circadian clock system in the mammalian retina.
    Bioessays Volume: 30 Page(s): 624 - 633
    07/01/2008 Authors: Tosini G; Pozdeyev N; Sakamoto K; Iuvone PM
  • Dopamine modulates diurnal and circadian rhythms of protein phosphorylation in photoreceptor cells of mouse retina.
    Eur J Neurosci Volume: 27 Page(s): 2691 - 2700
    05/01/2008 Authors: Pozdeyev N; Tosini G; Li L; Ali F; Rozov S; Lee RH; Iuvone PM
  • Evidence for an overlapping role of CLOCK and NPAS2 transcription factors in liver circadian oscillators.
    Mol Cell Biol Volume: 28 Page(s): 3070 - 3075
    05/01/2008 Authors: Bertolucci C; Cavallari N; Colognesi I; Aguzzi J; Chen Z; Caruso P; Fo A; Tosini G; Bernardi F; Pinotti M
  • Analysis of daily and circadian gene expression in the rat pineal gland.
    Neurosci Res Volume: 60 Page(s): 192 - 198
    02/01/2008 Authors: Fukuhara C; Tosini G
  • Localization of a circadian clock in mammalian photoreceptors.
    FASEB J Volume: 21 Page(s): 3866 - 3871
    12/01/2007 Authors: Tosini G; Davidson AJ; Fukuhara C; Kasamatsu M; Castanon-Cervantes O
  • Seasonal and diurnal melatonin production in exercising sled dogs.
    Comp Biochem Physiol A Mol Integr Physiol Volume: 147 Page(s): 863 - 867
    08/01/2007 Authors: Dunlap KL; Reynolds AJ; Tosini G; Kerr WW; Duffy LK
  • Clock gene expression in the rat retina: effects of lighting conditions and photoreceptor degeneration.
    Brain Res Volume: 1159 Page(s): 134 - 140
    07/23/2007 Authors: Tosini G; Kasamatsu M; Sakamoto K
  • Effect of photoreceptor degeneration on circadian photoreception and free-running period in the Royal College of Surgeons rat.
    Brain Res Volume: 1148 Page(s): 76 - 82
    05/07/2007 Authors: Tosini G; Aguzzi J; Bullock NM; Liu C; Kasamatsu M
  • Locomotor activity in rodents.
    Methods Mol Biol Volume: 362 Page(s): 95 - 101
    01/01/2007 Authors: Tosini G
  • Evolution of melanopsin photoreceptors: discovery and characterization of a new melanopsin in nonmammalian vertebrates.
    PLoS Biol Volume: 4 Page(s): e254
    07/01/2006 Authors: Bellingham J; Chaurasia SS; Melyan Z; Liu C; Cameron MA; Tarttelin EE; Iuvone PM; Hankins MW; Tosini G; Lucas RJ
  • Paradoxical effects of NPY in the suprachiasmatic nucleus.
    Eur J Neurosci Volume: 23 Page(s): 2488 - 2494
    05/01/2006 Authors: Gamble KL; Paul KN; Karom MC; Tosini G; Albers HE
  • Spontaneous internal desynchronization of locomotor activity and body temperature rhythms from plasma melatonin rhythm in rats exposed to constant dim light.
    J Circadian Rhythms Volume: 4 Page(s): 6
    04/04/2006 Authors: Aguzzi J; Bullock NM; Tosini G
  • Intraocular injection of kainic acid does not abolish the circadian rhythm of arylalkylamine N-acetyltransferase mRNA in rat photoreceptors.
    Mol Vis Volume: 12 Page(s): 117 - 124
    02/23/2006 Authors: Sakamoto K; Liu C; Kasamatsu M; Iuvone PM; Tosini G
  • Time keeping by the quail's eye: circadian regulation of melatonin production.
    Gen Comp Endocrinol Volume: 145 Page(s): 232 - 236
    02/01/2006 Authors: Steele CT; Tosini G; Siopes T; Underwood H
  • Regulation of arylalkylamine N-acetyltransferase (AANAT) in the retina.
    Chronobiol Int Volume: 23 Page(s): 381 - 391
    01/01/2006 Authors: Tosini G; Chaurasia SS; Michael Iuvone P
  • Dopamine regulates melanopsin mRNA expression in intrinsically photosensitive retinal ganglion cells.
    Eur J Neurosci Volume: 22 Page(s): 3129 - 3136
    12/01/2005 Authors: Sakamoto K; Liu C; Kasamatsu M; Pozdeyev NV; Iuvone PM; Tosini G
  • AMPA/kainate receptor antagonist DNQX blocks the acute increase of Per2 mRNA levels in most but not all areas of the SCN.
    Brain Res Mol Brain Res Volume: 139 Page(s): 129 - 136
    09/13/2005 Authors: Paul KN; Fukuhara C; Karom M; Tosini G; Albers HE
  • Circadian clocks, clock networks, arylalkylamine N-acetyltransferase, and melatonin in the retina.
    Prog Retin Eye Res Volume: 24 Page(s): 433 - 456
    07/01/2005 Authors: Iuvone PM; Tosini G; Pozdeyev N; Haque R; Klein DC; Chaurasia SS
  • Molecular cloning, localization and circadian expression of chicken melanopsin (Opn4): differential regulation of expression in pineal and retinal cell types.
    J Neurochem Volume: 92 Page(s): 158 - 170
    01/01/2005 Authors: Chaurasia SS; Rollag MD; Jiang G; Hayes WP; Haque R; Natesan A; Zatz M; Tosini G; Liu C; Korf HW
  • Effect of space flight on circadian rhythms.
    Adv Space Biol Med Volume: 10 Page(s): 165 - 174
    01/01/2005 Authors: Tosini G; Aguzzi J
  • Effect of long-term exposure to constant dim light on the circadian system of rats.
    Neurosignals Volume: 14 Page(s): 117 - 125
    01/01/2005 Authors: Fukuhara C; Aguzzi J; Bullock N; Tosini G
  • Classical photoreceptors regulate melanopsin mRNA levels in the rat retina.
    J Neurosci Volume: 24 Page(s): 9693 - 9697
    10/27/2004 Authors: Sakamoto K; Liu C; Tosini G
  • Circadian rhythms in the retina of rats with photoreceptor degeneration.
    J Neurochem Volume: 90 Page(s): 1019 - 1024
    08/01/2004 Authors: Sakamoto K; Liu C; Tosini G
  • Diurnal rhythms of tryptophan hydroxylase 1 and 2 mRNA expression in the rat retina.
    Neuroreport Volume: 15 Page(s): 1497 - 1500
    06/28/2004 Authors: Liang J; Wessel JH; Iuvone PM; Tosini G; Fukuhara C
  • Tetrodotoxin administration in the suprachiasmatic nucleus prevents NMDA-induced reductions in pineal melatonin without influencing Per1 and Per2 mRNA levels.
    Eur J Neurosci Volume: 19 Page(s): 2808 - 2814
    05/01/2004 Authors: Paul KN; Gamble KL; Fukuhara C; Novak CM; Tosini G; Albers HE
  • Gating of the cAMP signaling cascade and melatonin synthesis by the circadian clock in mammalian retina.
    J Neurosci Volume: 24 Page(s): 1803 - 1811
    02/25/2004 Authors: Fukuhara C; Liu C; Ivanova TN; Chan GC-K; Storm DR; Iuvone PM; Tosini G
  • Localization of Aa-nat mRNA in the rat retina by fluorescence in situ hybridization and laser capture microdissection.
    Cell Tissue Res Volume: 315 Page(s): 197 - 201
    02/01/2004 Authors: Liu C; Fukuhara C; Wessel JH; Iuvone PM; Tosini G
  • Analysis of gene expression following norepinephrine stimulation in the rat pineal gland using DNA microarray technique.
    J Pineal Res Volume: 35 Page(s): 196 - 203
    10/01/2003 Authors: Fukuhara C; Dirden JC; Tosini G
  • Induction of photosensitivity in cultured rat pineal affects Aa-nat regulation.
    Brain Res Dev Brain Res Volume: 142 Page(s): 219 - 221
    05/14/2003 Authors: Fukuhara C; Tosini G
  • Peripheral circadian oscillators and their rhythmic regulation.
    Front Biosci Volume: 8 Page(s): d642 - d651
    05/01/2003 Authors: Fukuhara C; Tosini G
  • Gating of the cAMP signaling cascade by the circadian clock in mammalian retina
    Volume: 44 Page(s): U213 - U213
    05/01/2003 Authors: Tosini GG; Fukuhara C; Cuimei L; Ivanova TN; Chan GCK; Storm DR; Iuvone PM
  • Photic and circadian regulation of retinal melatonin in mammals.
    J Neuroendocrinol Volume: 15 Page(s): 364 - 369
    04/01/2003 Authors: Tosini G; Fukuhara C
  • Transduction of light in the suprachiasmatic nucleus: evidence for two different neurochemical cascades regulating the levels of Per1 mRNA and pineal melatonin.
    Neuroscience Volume: 119 Page(s): 137 - 144
    01/01/2003 Authors: Paul KN; Fukuhara C; Tosini G; Albers HE
  • The mammalian retina as a clock.
    Cell Tissue Res Volume: 309 Page(s): 119 - 126
    07/01/2002 Authors: Tosini G; Fukuhara C
  • Regulation of period 1 expression in cultured rat pineal.
    Neurosignals Volume: 11 Page(s): 103 - 114
    01/01/2002 Authors: Fukuhara C; Dirden JC; Tosini G
  • Photic regulation of melatonin in rat retina and the role of proteasomal proteolysis.
    Neuroreport Volume: 12 Page(s): 3833 - 3837
    12/04/2001 Authors: Fukuhara C; Dirden JC; Tosini G
  • Neuropeptide Y rapidly reduces Period 1 and Period 2 mRNA levels in the hamster suprachiasmatic nucleus.
    Neurosci Lett Volume: 314 Page(s): 119 - 122
    11/16/2001 Authors: Fukuhara C; Brewer JM; Dirden JC; Bittman EL; Tosini G; Harrington ME
  • The mammalian circadian clock shop.
    Semin Cell Dev Biol Volume: 12 Page(s): 295 - 303
    08/01/2001 Authors: Herzog ED; Tosini G
  • Regulation of AA-NAT and Period 1 mRNA levels in the rat retina.
    Volume: 42 Page(s): S776 - S776
    03/15/2001 Authors: Fukuhara C; Dirden JC; Tosini G
  • Induction of photosensitivity in neonatal rat pineal: Effect of age and light intensity.
    Volume: 42 Page(s): S361 - S361
    03/15/2001 Authors: Tosini G; Dirden JC; Fukuhara C
  • The circadian system of reptiles: a multioscillatory and multiphotoreceptive system.
    Physiol Behav Volume: 72 Page(s): 461 - 471
    03/01/2001 Authors: Tosini G; Bertolucci C; Fo A
  • Dynamic expression of a glutamate decarboxylase gene in multiple non-neural tissues during mouse development.
    BMC Dev Biol Volume: 1 Page(s): 1
    01/01/2001 Authors: Maddox DM; Condie BG
  • Rhythmic expression of Nocturnin mRNA in multiple tissues of the mouse.
    BMC Dev Biol Volume: 1 Page(s): 9
    01/01/2001 Authors: Wang Y; Osterbur DL; Megaw PL; Tosini G; Fukuhara C; Green CB; Besharse JC
  • Induction of photosensitivity in neonatal rat pineal gland.
    Proc Natl Acad Sci U S A Volume: 97 Page(s): 11540 - 11544
    10/10/2000 Authors: Tosini G; Doyle S; Geusz M; Menaker M
  • Melatonin circadian rhythm in the retina of mammals.
    Chronobiol Int Volume: 17 Page(s): 599 - 612
    09/01/2000 Authors: Tosini G
  • Circadian clocks: what makes them tick?
    Chronobiol Int Volume: 17 Page(s): 433 - 451
    07/01/2000 Authors: Zordan M; Costa R; Macino G; Fukuhara C; Tosini G
  • Circadian expression of period 1, period 2, and arylalkylamine N-acetyltransferase mRNA in the rat pineal gland under different light conditions.
    Neurosci Lett Volume: 286 Page(s): 167 - 170
    06/09/2000 Authors: Fukuhara C; Dirden JC; Tosini G
  • Dopamine inhibits melatonin release in the mammalian retina: in vitro evidence.
    Neurosci Lett Volume: 286 Page(s): 119 - 122
    06/02/2000 Authors: Tosini G; Dirden JC
  • Melatonin synthesis in cultured retina of mammals is increased by serotonin, but not by tryptophan or 5-hydroxy-L-tryptophan.
    Volume: 40 Page(s): S611 - S611
    03/15/1999 Authors: Tosini G; Menaker M
  • The tau mutation affects temperature compensation of hamster retinal circadian oscillators.
    Neuroreport Volume: 9 Page(s): 1001 - 1005
    04/20/1998 Authors: Tosini G; Menaker M
  • The clock in the mouse retina: melatonin synthesis and photoreceptor degeneration.
    Brain Res Volume: 789 Page(s): 221 - 228
    04/13/1998 Authors: Tosini G; Menaker M
  • Multioscillatory circadian organization in a vertebrate, iguana iguana.
    J Neurosci Volume: 18 Page(s): 1105 - 1114
    02/01/1998 Authors: Tosini G; Menaker M
  • Evolution of circadian organization in vertebrates.
    Braz J Med Biol Res Volume: 30 Page(s): 305 - 313
    03/01/1997 Authors: Menaker M; Moreira LF; Tosini G
  • Circadian control of melatonin synthesis within the mammalian retina
    Volume: 69 Page(s): S119 - S119
    01/01/1997 Authors: Menaker M; Tosini G
  • Circadian rhythms in cultured mammalian retina.
    Science Volume: 272 Page(s): 419 - 421
    04/19/1996 Authors: Tosini G; Menaker M
  • The pineal complex and melatonin affect the expression of the daily rhythm of behavioral thermoregulation in the green iguana.
    J Comp Physiol A Volume: 179 Page(s): 135 - 142
    01/01/1996 Authors: Tosini G; Menaker M
  • Dermal photoreceptors regulate basking behavior in the lizard Podarcis muralis.
    Physiol Behav Volume: 59 Page(s): 195 - 198
    01/01/1996 Authors: Tosini G; Avery RA
  • Circadian rhythm of body temperature in an ectotherm (Iguana iguana).
    J Biol Rhythms Volume: 10 Page(s): 248 - 255
    09/01/1995 Authors: Tosini G; Menaker M
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