School of Medicine Homepage
Emory University Shield
  • About
    • Our Vision
    • Academic Departments
    • Our Leadership
    • Health Care Partnerships
    • Diversity, Equity, & Inclusion
    • Location
    • Supporting Our People
    • Our Faculty
    • History
    • News
    • Events
    • Contact Us
  • Education
    • Degree and Certificate Programs
    • Academic Departments
    • Residents & Fellows
    • Postdoctoral Training
    • Continuing Medical Education
    • Admissions
    • Cost and Financial Aid
    • Student Resources
  • Research
    • Research Innovation
    • Conducting Research
    • Core Facilities
    • Research Centers
    • Research Training
    • Academic Departments
    • Find a Researcher
    • Research News
  • Clinical Experience
    • Where We Work
    • Caring for a Diverse Population
    • Faculty Clinical Experience
    • Advanced Patient Care
    • Academic Departments
    • Community Learning
  • Giving
  • Directory

Directory section navigation

  • Faculty Profiles

Emory University School of Medicine

  • About
    • Sub link
      Our Vision
    • Sub link
      Academic Departments
    • Sub link
      Our Leadership
    • Sub link
      Health Care Partnerships
    • Sub link
      Diversity, Equity, & Inclusion
    • Sub link
      Location
    • Sub link
      Supporting Our People
    • Sub link
      Our Faculty
    • Sub link
      History
    • Sub link
      News
    • Sub link
      Events
    • Sub link
      Contact Us
  • Education
    • Sub link
      Degree and Certificate Programs
    • Sub link
      Academic Departments
    • Sub link
      Residents & Fellows
    • Sub link
      Postdoctoral Training
    • Sub link
      Continuing Medical Education
    • Sub link
      Admissions
    • Sub link
      Cost and Financial Aid
    • Sub link
      Student Resources
  • Research
    • Sub link
      Research Innovation
    • Sub link
      Conducting Research
    • Sub link
      Core Facilities
    • Sub link
      Research Centers
    • Sub link
      Research Training
    • Sub link
      Academic Departments
    • Sub link
      Find a Researcher
    • Sub link
      Research News
  • Clinical Experience
    • Sub link
      Where We Work
    • Sub link
      Caring for a Diverse Population
    • Sub link
      Faculty Clinical Experience
    • Sub link
      Advanced Patient Care
    • Sub link
      Academic Departments
    • Sub link
      Community Learning
  • Giving
  • Directory
  • Home School of Medicine Home
  • Directory

Profile

Gordon Churchward PhD

  • Department of Microbiology and Immunology
    Professor
  • (404) 712-9943
  • gordon.churchward@emory.edu
  • Pubmed
  • Emory University School of Medicine
    Microbiology and Immunology
    JB Williams School Of Medicine Building Suite 453
Head shot of Gordon Churchward

Overview

Gordon Churchward received his training in bacterial genetics and microbial physiology at the Universities of Leicester and Texas. Following a period as a post-doctoral fellow and junior faculty member at the University of Geneva he joined the Department faculty in 1985. As Assistant Dean for Medical Education and Student Affairs in the School of Medicine his focus is mainly on medical student education. He also directs Emorys NIH-funded post-baccalaureate PREP program whose goal is to prepare underrepresented minority students for entry into doctoral programs.

Research:
Transmissible antibody resistance and pathogenesis of group A streptococcus; mechanisms of transposition.

Academic Appointment

  • Assistant Dean of Medical Education and Student Affairs, Emory University School of Medicine
  • Professor, Department of Microbiology and Immunology, Emory University School of Medicine

Education

Degrees

  • PhD from University of Leicester
  • BS from University of Newcastle upon Tyne

Research

Focus

  • Maintenance and dissemination of genes conferring antibiotic resistance and bacterial pathogenesis; regulation of replication of bacterial plasmids and chromosomes; transposition of conjugative transposons; genetics of drug resistance in Mycobacteria; virulence gene expression in Streptococcus pyogenes.

Publications

  • Interweaving Curriculum Committees: A New Structure to Facilitate Oversight and Sustain Innovation.
    Acad Med Volume: 91 Page(s): 48 - 53
    01/01/2016 Authors: Stoddard HA; Brownfield ED; Churchward G; Eley JW
  • Regulation of streptokinase expression by CovR/S in Streptococcus pyogenes: CovR acts through a single high-affinity binding site.
    Microbiology (Reading) Volume: 155 Page(s): 566 - 575
    02/01/2009 Authors: Churchward G; Bates C; Gusa AA; Stringer V; Scott JR
  • The 52nd Annual Wind River Conference On Prokaryotic Biology--2008.
    J Bacteriol Volume: 190 Page(s): 7871 - 7875
    12/01/2008 Authors: Mann E; Zaunbrecher MA; Hitz K; Churchward G
  • Back to the future: the new ICE age.
    Mol Microbiol Volume: 70 Page(s): 554 - 556
    11/01/2008 Authors: Churchward G
  • Control of Streptococcus pyogenes virulence: modeling of the CovR/S signal transduction system.
    J Theor Biol Volume: 246 Page(s): 113 - 128
    05/07/2007 Authors: Mitrophanov AY; Churchward G; Borodovsky M
  • The two faces of Janus: virulence gene regulation by CovR/S in group A streptococci.
    Mol Microbiol Volume: 64 Page(s): 34 - 41
    04/01/2007 Authors: Churchward G
  • Unraveling the regulatory network in Streptococcus pyogenes: the global response regulator CovR represses rivR directly.
    J Bacteriol Volume: 189 Page(s): 1459 - 1463
    02/01/2007 Authors: Roberts SA; Churchward GG; Scott JR
  • Phosphorylation of the group A Streptococcal CovR response regulator causes dimerization and promoter-specific recruitment by RNA polymerase.
    J Bacteriol Volume: 188 Page(s): 4620 - 4626
    07/01/2006 Authors: Gusa AA; Gao J; Stringer V; Churchward G; Scott JR
  • The integrase of the conjugative transposon Tn916 directs strand- and sequence-specific cleavage of the origin of conjugal transfer, oriT, by the endonuclease Orf20.
    J Bacteriol Volume: 188 Page(s): 2207 - 2213
    03/01/2006 Authors: Rocco JM; Churchward G
  • Binding of the global response regulator protein CovR to the sag promoter of Streptococcus pyogenes reveals a new mode of CovR-DNA interaction.
    J Biol Chem Volume: 280 Page(s): 38948 - 38956
    11/25/2005 Authors: Gao J; Gusa AA; Scott JR; Churchward G
  • Xis protein of the conjugative transposon Tn916 plays dual opposing roles in transposon excision.
    Mol Microbiol Volume: 41 Page(s): 1459 - 1467
    09/01/2001 Authors: Hinerfeld D; Churchward G
  • Specific binding of integrase to the origin of transfer (oriT) of the conjugative transposon Tn916.
    J Bacteriol Volume: 183 Page(s): 2947 - 2951
    05/01/2001 Authors: Hinerfeld D; Churchward G
  • Coupling sequences flanking Tn916 do not determine the affinity of binding of integrase to the transposon ends and adjacent bacterial DNA.
    Plasmid Volume: 43 Page(s): 123 - 129
    03/01/2000 Authors: Pethel B; Churchward G
  • Interactions of the integrase protein of the conjugative transposon Tn916 with its specific DNA binding sites.
    J Bacteriol Volume: 181 Page(s): 6114 - 6123
    10/01/1999 Authors: Jia Y; Churchward G
  • The frequency of conjugative transposition of Tn916 is not determined by the frequency of excision.
    J Bacteriol Volume: 181 Page(s): 5414 - 5418
    09/01/1999 Authors: Marra D; Pethel B; Churchward GG; Scott JR
  • Excision of a conjugative transposon in vitro by the Int and Xis proteins of Tn916.
    Nucleic Acids Res Volume: 25 Page(s): 4061 - 4066
    10/15/1997 Authors: Rudy C; Taylor KL; Hinerfeld D; Scott JR; Churchward G
  • DNA binding by the Xis protein of the conjugative transposon Tn916.
    J Bacteriol Volume: 179 Page(s): 2567 - 2572
    04/01/1997 Authors: Rudy CK; Scott JR; Churchward G
  • Specific DNA cleavage mediated by the integrase of conjugative transposon Tn916.
    J Bacteriol Volume: 179 Page(s): 1117 - 1125
    02/01/1997 Authors: Taylor KL; Churchward G
  • Genetic analysis of the Mycobacterium smegmatis rpsL promoter.
    J Bacteriol Volume: 178 Page(s): 3564 - 3571
    06/01/1996 Authors: Kenney TJ; Churchward G
  • Tn916 target DNA sequences bind the C-terminal domain of integrase protein with different affinities that correlate with transposon insertion frequency.
    J Bacteriol Volume: 177 Page(s): 1938 - 1946
    04/01/1995 Authors: Lu F; Churchward G
  • Conjugative transposition.
    Annu Rev Microbiol Volume: 49 Page(s): 367 - 397
    01/01/1995 Authors: Scott JR; Churchward GG
  • Cloning and sequence analysis of the rpsL and rpsG genes of Mycobacterium smegmatis and characterization of mutations causing resistance to streptomycin.
    J Bacteriol Volume: 176 Page(s): 6153 - 6156
    10/01/1994 Authors: Kenney TJ; Churchward G
  • Conjugative transposition: Tn916 integrase contains two independent DNA binding domains that recognize different DNA sequences.
    EMBO J Volume: 13 Page(s): 1541 - 1548
    04/01/1994 Authors: Lu F; Churchward G
  • Replication origin mutations affecting binding of pSC101 plasmid-encoded Rep initiator protein.
    J Bacteriol Volume: 174 Page(s): 456 - 463
    01/01/1992 Authors: Arini A; Tuscan M; Churchward G
  • Control of cyclic chromosome replication in Escherichia coli.
    Microbiol Rev Volume: 55 Page(s): 459 - 475
    09/01/1991 Authors: Bremer H; Churchward G
  • A copy-number mutant of plasmid pSC101.
    Mol Microbiol Volume: 5 Page(s): 631 - 640
    03/01/1991 Authors: Xia GX; Manen D; Goebel T; Linder P; Churchward G; Caro L
  • Transcription events in the origin of replication of plasmid pSC101.
    J Bacteriol Volume: 171 Page(s): 6482 - 6492
    12/01/1989 Authors: Manen D; Izaurralde E; Churchward G; Caro L
  • REPLICATION OF THE ESCHERICHIA-COLI PLASMID PSC101
    EXPERIENTIA Volume: 43 Page(s): 668 - 668
    06/15/1987 Authors: MANEN D; GOEBEL T; CHURCHWARD G; CARO L
  • Replication of pSC101: effects of mutations in the E. coli DNA binding protein IHF.
    Mol Gen Genet Volume: 204 Page(s): 85 - 89
    07/01/1986 Authors: Gamas P; Burger AC; Churchward G; Caro L; Galas D; Chandler M
  • REPLICATION OF THE ESCHERICHIA-COLI PLASMID PSC101
    EXPERIENTIA Volume: 42 Page(s): 690 - 690
    06/15/1986 Authors: MANEN D; GOEBEL T; CHURCHWARD G; CARO L
  • REPLICATION OF THE TETRACYCLINE RESISTANCE PLASMID PSC101
    EXPERIENTIA Volume: 42 Page(s): 103 - 103
    01/15/1986 Authors: CHURCHWARD G; XIA GX; GOEBEL T; MANEN D; OTHONIZAURRAULDE E; CARO L
  • INSERTION MUTAGENESIS AND TRANSCRIPTION MAPPING OF PLASMID PSC101 REPLICATION GENES
    JOURNAL OF CELLULAR BIOCHEMISTRY Page(s): 171 - 171
    01/01/1986 Authors: CHURCHWARD G; IZAURRALDE E; MANEN D
  • Initiation of chromosome replication in Escherichia coli after induction of dnaA gene expression from a lac promoter.
    J Bacteriol Volume: 164 Page(s): 922 - 924
    11/01/1985 Authors: Bremer H; Churchward G
  • An essential replication gene, repA, of plasmid pSC101 is autoregulated.
    J Mol Biol Volume: 181 Page(s): 383 - 393
    02/05/1985 Authors: Linder P; Churchward G; Xia GX; Yu YY; Caro L
  • REPLICATION OF THE TETRACYCLINE RESISTANCE PLASMID PSC101
    EXPERIENTIA Volume: 41 Page(s): 797 - 797
    01/01/1985 Authors: CHURCHWARD G; XIA GX; GOEBEL T; MANEN D; OTHONIZAURRAULDE E; CARO L
  • A pSC101-derived plasmid which shows no sequence homology to other commonly used cloning vectors.
    Gene Volume: 31 Page(s): 165 - 171
    11/01/1984 Authors: Churchward G; Belin D; Nagamine Y
  • REPLICATION OF PSC101 - ANALYSIS OF PLASMID ENCODED FUNCTIONS
    EXPERIENTIA Volume: 40 Page(s): 630 - 630
    01/01/1984 Authors: LINDER P; CHURCHWARD G; XIA GX; CARO L
  • Replication functions encoded by the plasmid pSC101.
    Adv Exp Med Biol Volume: 179 Page(s): 209 - 214
    01/01/1984 Authors: Churchward G; Linder P; Caro L
  • Plasmid pSC101 replication mutants generated by insertion of the transposon Tn1000.
    J Mol Biol Volume: 170 Page(s): 287 - 303
    10/25/1983 Authors: Linder P; Churchward G; Caro L
  • The repA2 gene of the plasmid R100.1 encodes a repressor of plasmid replication.
    Plasmid Volume: 10 Page(s): 148 - 155
    09/01/1983 Authors: Liu CP; Churchward G; Caro L
  • The nucleotide sequence of replication and maintenance functions encoded by plasmid pSC101.
    Nucleic Acids Res Volume: 11 Page(s): 5645 - 5659
    08/25/1983 Authors: Churchward G; Linder P; Caro L
  • Increased expression of the dnaA gene has no effect on DNA replication in a dnaA+ strain of Escherichia coli.
    Mol Gen Genet Volume: 192 Page(s): 506 - 508
    01/01/1983 Authors: Churchward G; Holmans P; Bremer H
  • Transcription in bacteria at different DNA concentrations.
    J Bacteriol Volume: 150 Page(s): 572 - 581
    05/01/1982 Authors: Churchward G; Bremer H; Young R
  • Macromolecular composition of bacteria.
    J Theor Biol Volume: 94 Page(s): 651 - 670
    02/07/1982 Authors: Churchward G; Bremer H; Young R
  • REPLICATION OF PSC101 - ANALYSIS OF PLASMID ENCODED FUNCTIONS
    EXPERIENTIA Volume: 38 Page(s): 1379 - 1379
    01/01/1982 Authors: LINDER P; CHURCHWARD G; CARO L
  • Growth rate-dependent control of chromosome replication initiation in Escherichia coli.
    J Bacteriol Volume: 145 Page(s): 1232 - 1238
    03/01/1981 Authors: Churchward G; Estiva E; Bremer H
  • Synthesis and function of ribonucleic acid polymerase and ribosomes in Escherichia coli B/r after a nutritional shift-up.
    J Bacteriol Volume: 143 Page(s): 1332 - 1344
    09/01/1980 Authors: Shepherd N; Churchward G; Bremer H
  • Synthesis and activity of ribonucleic acid polymerase in Escherichia coli.
    J Bacteriol Volume: 141 Page(s): 1098 - 1108
    03/01/1980 Authors: Shepherd NS; Churchward G; Bremer H
  • ISOLATION OF PSC101 COPY NUMBER MUTANTS
    EXPERIENTIA Volume: 36 Page(s): 750 - 751
    01/01/1980 Authors: LINDER P; CHURCHWARD G; CARO L
  • Relation between growth and replication in bacteria.
    J Theor Biol Volume: 81 Page(s): 533 - 545
    12/07/1979 Authors: Bremer H; Churchward G; Young R
  • REPLICATION AND TRANSCRIPTION IN ESCHERICHIA-COLI B-R AND IN A DERIVATIVE WITH ABERRANT INITIATION CONTROL
    TEXAS JOURNAL OF SCIENCE Volume: 31 Page(s): 113 - 113
    01/01/1979 Authors: BREMER H; CHURCHWARD G; YOUNG R
  • Age fractionation in bacteria by membrane elution: relation between age distribution and elution profile.
    J Theor Biol Volume: 74 Page(s): 69 - 81
    09/20/1978 Authors: Bremer H; Churchward G
  • An examination of the Cooper-Helmstetter theory of DNA replication in bacteria and its underlying assumptions.
    J Theor Biol Volume: 69 Page(s): 645 - 654
    12/21/1977 Authors: Bremer H; Churchward G
  • Determination of deoxyribonucleic acid replication time in exponentially growing Escherichia coli B/r.
    J Bacteriol Volume: 130 Page(s): 1206 - 1213
    06/01/1977 Authors: Churchward G; Bremer H
  • Deoxyribonucleic acid synthesis after inhibition of initiation of rounds of replication in Escherichia coli B/r.
    J Bacteriol Volume: 130 Page(s): 692 - 697
    05/01/1977 Authors: Bremer H; Churchward G
  • Initiation and termination of deoxyribonucleic acid replication in bacteria after a stepwise increase in the velocity of replication.
    J Bacteriol Volume: 130 Page(s): 92 - 99
    04/01/1977 Authors: Bremer H; Young R; Churchward G
  • Envelope synthesis during the cell cycle in Escherichia coli B/r.
    J Mol Biol Volume: 105 Page(s): 245 - 261
    08/05/1976 Authors: Churchward GG; Holland IB
  • Induced synthesis of an envelope protein by thymine starvation of E. coli B/r.
    FEBS Lett Volume: 62 Page(s): 347 - 350
    03/01/1976 Authors: Churchward GG; Holland IB
Read more publications Fewer publications
Directory
  • Faculty Profiles
Emory University Homepage

Contact & Location

Emory University School of Medicine
100 Woodruff Circle
Atlanta, GA  30322 USA
  • Contact Us
  • Maps & Directions
  • Careers

Information For

  • Alumni
  • Faculty & Staff
  • Patients
  • Residents & Fellows
  • Students
Support the School of Medicine School of Medicine Intranet
facebook facebook twitter twitter linkedin linkedin instagram instagram youtube youtube
© 2025 Emory University
  • Privacy Policy
  • Emergency Information
  • EEO Employer-Disability/Veteran Statements