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Profile

Ghazala O'Keefe

  • Department of Ophthalmology
    Associate Professor
  • g.d.okeefe@emory.edu
Head shot of Ghazala O'Keefe

Overview

Ghazala A. Datoo OKeefe, MD, joined the Emory Eye Center in 2015. Dr. OKeefe brings expertise in medical retina and uveitis to the Eye Center, helping care for an expanding uveitis patient population. She is the director of the Medical Retina and Uveitis fellowship and is the Service Director for the Section of Uveitis and Retinal Vasculitis.

She has received the following recognitions:
Boisfeuillet Jones Medal, Emory University, 2006
Hidden Gem, Emory University School of Medicine, 2019
Queen of Cases Teaching Award, Department of Ophthalmology, 2020
Doctors Day Recognition, Emory School of Medicine, 2022

Dr. OKeefe received her MD from the Johns Hopkins University School of Medicine in 2010. She completed a residency in Ophthalmology at the University of Southern California (USC) and the Doheny Eye Institute, followed by a medical retina and uveitis fellowship at the University of California, Los Angeles (UCLA) and the Doheny Eye Institute.

Her primary practice location is the Emory Eye Center main location on the Emory University/Emory Healthcare campus. Her clinical work focuses on inflammatory and infectious diseases of the eyes as well as retinal degenerations, age-related macular degeneration (AMD), and diabetic retinopathy.

Dr. OKeefe teaches medical students as well as ophthalmology residents and fellows at the Eye Center. In 2016, she helped lead a successful effort to increase access to more effective, higher-cost injection medications for patients at Grady Medical Center. She worked on collaborative projects with other departments to improve co-ordination of patient care for those with complex eye disease.

Her research interests include infectious and auto-immune diseases of the eye, AMD, diabetic retinopathy, and retinal imaging modalities.

Dr. O'Keefe is has completed courses at Emory in Quality Improvement, Health Services Research, and the Emory Professional Leadership Enrichment and Development Program (EM-ProLEAD). She has served as a founding member for Emory Alliance for Women in Medicine and Science (EAWiMS) and for Women in Ophthalmology at Emory (WOE).

National Recognition

She is a member of the Online Education Committtee for the American Academy of Ophthlamology (AAO), is the uveitis section editor for EyeWiki, and serves on the Executive Board of the American Uveitis Society (AUS).

She has been an invited speaker at regional, national, and international conferences and is the Director of the Southeastern Vitreoretinal Seminar, held yearly in Atlanta, GA.

Dr. OKeefes peer-reviewed articles have been published in a number of leading journals, including Ophthalmology, Ocular Immunology and Inflammation, Survey of Ophthalmology, Ophthalmic Surgery Lasers and Imaging Retina, British Journal of Ophthalmology, Indian Journal of Ophthalmology, Neurosurgery, and Annals of Surgical Oncology.

Areas of Clinical Interest

Infectious and Inflammatory diseases of the eye
Retinal degenerations, including Age-related macular degeneration
Diabetic retinopathy
Retinal imaging modalities

Academic Appointment

  • Assistant Professor, Emory University

Education

Degrees

  • MD from Johns Hopkins University
  • BS, Biology from Emory University

Research

Publications

  • Visual Morbidity and Outcomes of Scleritis Associated with Intraocular Inflammation Compared to Isolated Scleritis.
    Ocul Immunol Inflamm Volume: 32 Page(s): 947 - 954
    08/01/2024 Authors: Liao A; Fajoles-Vasseneix C; Rali A; Ward L; Fernandes A; Patel PS; O'Keefe G; Shantha JG; Yeh S
  • TOWARD AN IMAGING-CENTRIC DEFINITION OF NONPARANEOPLASTIC AUTOIMMUNE RETINOPATHY.
    Retina Volume: 44 Page(s): 868 - 877
    05/01/2024 Authors: Xu LT; Zheng A; Shantha JG; Yeh S; Yan J; Hubbard GB; Patel PS; Waltuck J; O'Keefe G; Jain N
  • A UNIQUE INDOCYANINE GREEN ANGIOGRAPHY FEATURE IN SARCOIDOSIS.
    Retin Cases Brief Rep Volume: 17 Page(s): 728 - 729
    11/01/2023 Authors: Hossain HA; O'Keefe G
  • Characterization of Fluorescein Angiography Features in Pediatric Patients with Uveitis.
    Ocul Immunol Inflamm Volume: 31 Page(s): 1635 - 1639
    10/01/2023 Authors: Hossain HA; Ye S; Ward L; O'Keefe GD
  • Diabetic retinopathy in African-Americans with end-stage kidney disease: a cross-sectional study on prevalence and impact on quality of life.
    BMJ Open Diabetes Res Care Volume: 11
    07/01/2023 Authors: Egeolu M; Caleon RL; Manishimwe E; Zabala ZE; Moazzami B; Gerges A; O'Keefe GD; Navarrete J; Galindo RJ; McCoy RG
  • Morphological characteristics of eyes with neovascular age-related macular degeneration and good long-term visual outcomes after anti-VEGF therapy.
    Br J Ophthalmol Volume: 107 Page(s): 399 - 405
    03/01/2023 Authors: Fang M; Chanwimol K; Maram J; Datoo O'Keefe GA; Wykoff CC; Sarraf D; Brown A; Lampen SIR; Zhou B; Rusakevich AM
  • Health Literacy, Medication Adherence, and Quality of Life in Patients With Uveitis.
    Ocul Immunol Inflamm Volume: 30 Page(s): 1060 - 1067
    07/01/2022 Authors: Mueller CM; Ward L; O'Keefe GAD
  • Correlation of Social Determinants of Health with Outcomes of Pediatric Uveitis
    Volume: 63
    06/01/2022 Authors: Mogendi S; O'Keefe G
  • Optical coherence tomography (OCT) findings in a pediatric uveitis cohort
    Volume: 63
    06/01/2022 Authors: Thomas J; Lam P; Ward L; Regueiro M; O'Keefe G; Yeh S; Shantha J
  • Risk Factors for Retinal Detachment in Acute Retinal Necrosis.
    Ophthalmol Retina Volume: 6 Page(s): 478 - 483
    06/01/2022 Authors: Bavinger JC; Anthony CL; Lindeke-Myers AT; Lynch S; Xu LT; Barnett J; Levine D; Patel P; Shah R; Jain N
  • Progress in the diagnosis of ocular sarcoidosis.
    Indian J Ophthalmol Volume: 70 Page(s): 1121 - 1129
    04/01/2022 Authors: O'Keefe GAD; Rao NA
  • Expanded Clinical Spectrum of Pentosan Polysulfate Maculopathy: A Macula Society Collaborative Study.
    Ophthalmol Retina Volume: 6 Page(s): 219 - 227
    03/01/2022 Authors: Jain N; Liao A; Garg SJ; Patel SN; Wykoff CC; Yu HJ; London NJS; Khurana RN; Zacks DN; Macula Society Pentosan Polysulfate Maculopathy Study Group
  • Clinical Correlation between Acute Exudative Polymorphous Paraneoplastic Vitelliform Maculopathy and Metastatic Melanoma Disease Activity: A 48-month Longitudinal Case Report.
    Ocul Immunol Inflamm Volume: 30 Page(s): 330 - 337
    02/17/2022 Authors: Mueller CM; Hojjatie SL; Lawson DH; Jain N; Robinson J; Khan MK; Yushak ML; A Datoo O'Keefe G
  • The impact of COVID-19: variations in volumes and characteristics of retina surgeries.
    BMC Surg Volume: 22 Page(s): 41
    02/05/2022 Authors: Shabto JM; Faaborg-Andersen C; O'Keefe GA
  • Commentary on: Long-term Outcomes of Ophthalmic and Retinal Artery Occlusion After Cosmetic Facial Filler Injection.
    Aesthet Surg J Volume: 42 Page(s): 208 - 209
    01/12/2022 Authors: O'Keefe GAD
  • Cytopathology of Vitreous Specimens in Acute Retinal Necrosis.
    Ocul Immunol Inflamm Volume: 30 Page(s): 1609 - 1616
    01/01/2022 Authors: Hojjatie SL; Shantha JG; O'Keefe GD; Kraft CS; Voloschin A; Grossniklaus H; Yeh S
  • Clinical outcomes following intravitreal methotrexate for primary vitreoretinal lymphoma.
    Int J Retina Vitreous Volume: 7 Page(s): 72
    12/04/2021 Authors: Anthony CL; Bavinger JC; Shantha JG; O'Keefe GD; Pearce WA; Voloschin A; Grossniklaus HE; Yeh S
  • Diagnostic retinal biopsy in the management of secondary non-CNS vitreoretinal lymphoma masquerading as viral retinitis: a case report.
    Int J Retina Vitreous Volume: 7 Page(s): 58
    10/11/2021 Authors: Rali A; Xu LT; Craven C; Cohen JB; Yeh S; Grossniklaus HE; O'Keefe GD
  • Outcomes of Infectious Endophthalmitis in Patients with Systemic Antibiotic Allergies to Penicillins, Cephalosporins, or Vancomycin.
    Ophthalmol Retina Volume: 5 Page(s): 901 - 909
    09/01/2021 Authors: Meyer BI; Berry DE; Cribbs BE; Hendrick A; Jain N; Hubbard GB; O'Keefe G; Patel PS; Shantha JG; Yan J
  • Postacute Sequelae of SARS-CoV-2 Infection and Impact on Quality of Life 1-6 Months After Illness and Association With Initial Symptom Severity.
    Open Forum Infect Dis Volume: 8 Page(s): ofab352
    08/01/2021 Authors: O'Keefe JB; Minton HC; Morrow M; Johnson C; Moore MA; O'Keefe GAD; Benameur K; Higdon J; Fairley JK
  • Clinical course and outcomes of COVID-19 in rheumatic disease patients: a case cohort study with a diverse population.
    Clin Rheumatol Volume: 40 Page(s): 2633 - 2642
    07/01/2021 Authors: Arleo T; Tong D; Shabto J; O'Keefe G; Khosroshahi A
  • Efficacy and Safety of Intravitreal Gene Therapy for Leber Hereditary Optic Neuropathy Treated within 6 Months of Disease Onset.
    Ophthalmology Volume: 128 Page(s): 649 - 660
    05/01/2021 Authors: Newman NJ; Yu-Wai-Man P; Carelli V; Moster ML; Biousse V; Vignal-Clermont C; Sergott RC; Klopstock T; Sadun AA; Barboni P
  • Use of a Telemedicine Risk Assessment Tool to Predict the Risk of Hospitalization of 496 Outpatients With COVID-19: Retrospective Analysis.
    JMIR Public Health Surveill Volume: 7 Page(s): e25075
    04/30/2021 Authors: O'Keefe JB; Tong EJ; Taylor TH; O'Keefe GAD; Tong DC
  • Description of symptom course in a telemedicine monitoring clinic for acute symptomatic COVID-19: a retrospective cohort study.
    BMJ Open Volume: 11 Page(s): e044154
    03/05/2021 Authors: O'Keefe JB; Tong EJ; O'Keefe GD; Tong DC
  • Discharge characteristics and care transitions of hospitalized patients with COVID-19.
    Healthc (Amst) Volume: 9 Page(s): 100512
    03/01/2021 Authors: Loerinc LB; Scheel AM; Evans ST; Shabto JM; O'Keefe GA; O'Keefe JB
  • Retinal vasculitis: A framework and proposal for a classification system.
    Surv Ophthalmol Volume: 66 Page(s): 54 - 67
    01/01/2021 Authors: Datoo O'Keefe GA; Rao N
  • Bilateral visual improvement with unilateral gene therapy injection for Leber hereditary optic neuropathy.
    Sci Transl Med Volume: 12
    12/09/2020 Authors: Yu-Wai-Man P; Newman NJ; Carelli V; Moster ML; Biousse V; Sadun AA; Klopstock T; Vignal-Clermont C; Sergott RC; Rudolph G
  • Characteristics and outcomes of COVID-19 positive patients with diabetes managed as outpatients.
    Diabetes Res Clin Pract Volume: 164 Page(s): 108229
    06/01/2020 Authors: Shabto JM; Loerinc L; O'Keefe GA; O'Keefe J
  • Characteristics and Outcomes of Patients with Non-Paraneoplastic Autoimmune Retinopathy
    Volume: 61
    06/01/2020 Authors: Xu L; Shantha JG; Yeh S; Yan J; Hubbard GB; Patel P; Jain N; O'Keefe G
  • Atypical Presentations of Birdshot Chorioretiopathy: A Comparative Longitudinal Study
    Volume: 61
    06/01/2020 Authors: Ahmad S; Price KW; Yeh S; O'Keefe G; Shantha JG
  • Clinical Presentation, Management, and Long-Term Outcomes of Pediatric Uveitis Patients at a Tertiary Referral Center in the Southeast
    Volume: 61
    06/01/2020 Authors: Hojjatie SL; Ghanouni A; Hicks BR; Yeh S; Shantha JG; O'Keefe GAD
  • Relapsing Uveitis due to Human T-lymphotropic Virus Type 1 in a Patient Living With HIV Diagnosed by Metagenomic Deep Sequencing.
    Open Forum Infect Dis Volume: 7 Page(s): ofaa078
    03/01/2020 Authors: Phadke VK; Shantha JG; O'Keefe G
  • Long-term multimodal imaging in acute posterior multifocal placoid pigment epitheliopathy and association with coxsackievirus exposure.
    PLoS One Volume: 15 Page(s): e0238080
    01/01/2020 Authors: Li AL; Palejwala NV; Shantha JG; O'Keefe G; Lee CS; Albini T; Yeh S
  • Phenotypic Spectrum of Pentosan Polysulfate Sodium-Associated Maculopathy: A Multicenter Study.
    JAMA Ophthalmol Volume: 137 Page(s): 1275 - 1282
    11/01/2019 Authors: Hanif AM; Armenti ST; Taylor SC; Shah RA; Igelman AD; Jayasundera KT; Pennesi ME; Khurana RN; Foote JE; O'Keefe GA
  • Strength of Association between Pentosan Polysulfate and a Novel Maculopathy.
    Ophthalmology Volume: 126 Page(s): 1464 - 1466
    10/01/2019 Authors: Hanif AM; Shah R; Yan J; Varghese JS; Patel SA; Cribbs BE; O'Keefe G; Hendrick AM; Shantha JG; Hubbard GB
  • Health Literacy, Adherence, and Quality of Life in Uveitis Patients
    Volume: 60
    07/01/2019 Authors: Mueller C; O'Keefe G
  • Association between a newly described pigmentary maculopathy and pentosan polysulfate sodium
    Volume: 60
    07/01/2019 Authors: Shah R; Hanif AM; Yan J; Cribbs B; O'Keefe G; Yeh S; Hendrick A; Shantha J; Hubbard GB; Patel P
  • Visual morbidity and outcomes in patients with scleritis associated with intraocular inflammation
    Volume: 60
    07/01/2019 Authors: Vasseneix C; O'Keefe G; Shantha J; Yeh S
  • Extranodal Rosai-Dorfman of the Pancreas Presents with Bilateral Granulomatous Anterior Uveitis.
    Ocul Oncol Pathol Volume: 5 Page(s): 229 - 233
    06/01/2019 Authors: Brown A; Branson SV; Datoo O'Keefe GA
  • Early Onset Neovascular Inflammatory Vitreoretinopathy Due to a De Novo CAPN5 Mutation: Report of a Case.
    Ocul Immunol Inflamm Volume: 27 Page(s): 706 - 708
    01/01/2019 Authors: O'Keefe G; Hanif AM; Mahajan VB; Jain N
  • Vogt-Koyanagi-Harada Disease Associated with Hepatitis B Vaccination.
    Ocul Immunol Inflamm Volume: 27 Page(s): 524 - 527
    01/01/2019 Authors: Sood AB; O'Keefe G; Bui D; Jain N
  • Decreased severity of age-related macular degeneration in amblyopic eyes.
    Br J Ophthalmol Volume: 102 Page(s): 1575 - 1578
    11/01/2018 Authors: Storey PP; Aziz HA; O'Keefe GAD; Borchert M; Lam LA; Puliafito CA; Olmos de Koo LC
  • Treatment Modalities and Visual Outcomes in Retinal Vasculitis
    Volume: 59
    07/01/2018 Authors: Christiansen J; Prinzi R; O'Keefe G
  • Vogt-Koyanagi-Harada disease.
    Surv Ophthalmol Volume: 62 Page(s): 1 - 25
    01/01/2017 Authors: O'Keefe GAD; Rao NA
  • A pre-retinal arterial loop causing a branch retinal artery occlusion.
    Ophthalmic Surg Lasers Imaging Retina Volume: 45 Page(s): 66 - 68
    01/01/2014 Authors: O'Keefe GAD; Sadda SR
  • Asian race/ethnicity as a risk factor for bile duct injury during cholecystectomy.
    Arch Surg Volume: 145 Page(s): 785 - 787
    08/01/2010 Authors: Downing SR; Datoo G; Oyetunji TA; Fullum T; Chang DC; Ahuja N
  • Persistent outpatient hyperglycemia is independently associated with survival, recurrence and malignant degeneration following surgery for hemispheric low grade gliomas.
    Neurol Res Volume: 32 Page(s): 442 - 448
    05/01/2010 Authors: Chaichana KL; McGirt MJ; Woodworth GF; Datoo G; Tamargo RJ; Weingart J; Olivi A; Brem H; Quinones-Hinojosa A
  • Recurrent disc herniation and long-term back pain after primary lumbar discectomy: review of outcomes reported for limited versus aggressive disc removal.
    Neurosurgery Volume: 64 Page(s): 338 - 344
    02/01/2009 Authors: McGirt MJ; Ambrossi GLG; Datoo G; Sciubba DM; Witham TF; Wolinsky J-P; Gokaslan ZL; Bydon A
  • Symptom recurrence after suboccipital decompression for pediatric Chiari I malformation: analysis of 256 consecutive cases.
    Childs Nerv Syst Volume: 24 Page(s): 1333 - 1339
    11/01/2008 Authors: McGirt MJ; Attenello FJ; Atiba A; Garces-Ambrossi G; Datoo G; Weingart JD; Carson B; Jallo GI
  • Use of Gliadel (BCNU) wafer in the surgical treatment of malignant glioma: a 10-year institutional experience.
    Ann Surg Oncol Volume: 15 Page(s): 2887 - 2893
    10/01/2008 Authors: Attenello FJ; Mukherjee D; Datoo G; McGirt MJ; Bohan E; Weingart JD; Olivi A; Quinones-Hinojosa A; Brem H
  • Intraoperative ultrasonography as a guide to patient selection for duraplasty after suboccipital decompression in children with Chiari malformation Type I.
    J Neurosurg Pediatr Volume: 2 Page(s): 52 - 57
    07/01/2008 Authors: McGirt MJ; Attenello FJ; Datoo G; Gathinji M; Atiba A; Weingart JD; Carson B; Jallo GI
  • Correlation of hindbrain CSF flow and outcome after surgical decompression for Chiari I malformation.
    Childs Nerv Syst Volume: 24 Page(s): 833 - 840
    07/01/2008 Authors: McGirt MJ; Atiba A; Attenello FJ; Wasserman BA; Datoo G; Gathinji M; Carson B; Weingart JD; Jallo GI
  • Outcome of Chiari-associated syringomyelia after hindbrain decompression in children: analysis of 49 consecutive cases.
    Neurosurgery Volume: 62 Page(s): 1307 - 1313
    06/01/2008 Authors: Attenello FJ; McGirt MJ; Gathinji M; Datoo G; Atiba A; Weingart J; Carson B; Jallo GI
  • Suboccipital decompression for Chiari malformation-associated scoliosis: risk factors and time course of deformity progression.
    J Neurosurg Pediatr Volume: 1 Page(s): 456 - 460
    06/01/2008 Authors: Attenello FJ; McGirt MJ; Atiba A; Gathinji M; Datoo G; Weingart J; Carson B; Jallo GI
  • Development of novel small molecule inhibitors targeting CXCR4 against cancer metastasis
    Volume: 66
    04/01/2006 Authors: Liang Z; Zhan W; Yoon Y; Datoo G; Snyder J; Liotta D; Shim H
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