Overview

Edward T. (Eddie) Morgan was born in Millport, Isle of Cumbrae, Scotland. He received a B.Sc. (Honours) in Pharmacology and a Ph.D. in Pharmacology from the University of Glasgow in 1976 and 1979. His dissertation (advisors Garth Powis and Paul Skett) was on the Effects of ethanol on hepatic microsomal drug metabolism. As a Postdoctoral Fellow with Minor J Coon at the University of Michigan from 1979-82, Dr. Morgan teamed with Dr. Dennis Koop to identify, purify and characterize a novel ethanol-induced P450 protein, CYP2E1, which plays an important role in the toxicology of many compounds, and may also contribute to alcohol-induced oxidative stress. Dr. Morgan then moved to the Karolinska Institute in Stockholm, Sweden where, working as a Visiting Scientist with Prof. Jan-ke Gustafsson from 1982-86, he was the first to conclusively demonstrate that expression of sex-specific forms of cytochrome P450 in rodents are regulated by the pulsatile pattern of Growth Hormone secretion. In 1986, he joined the faculty at Emory University, where he is now Professor of Pharmacology.
Dr. Morgans research interests at Emory have been focused on the regulation of hepatic cytochrome P450 enzymes by inflammatory and infectious stimuli, and he provided the first evidence that such regulation occurs via suppression of gene transcription. His current research interests are in interactions between host P450s and invading organisms in models of infection; and on post-translational regulation of P450s with a focus on Nitric Oxide.

Dr. Morgan has been the recipient of various awards including: Visiting Scientist Fellowships from the Swedish Medical Research Council and the Swedish Work Health Fund; a Faculty Development Award from the Pharmaceutical Manufacturers Association Foundation; and the Joseph G. Williams Memorial Lectureship from the University of South Florida. Dr. Morgan is a member of the American Society of Pharmacology and Experimental Therapeutics (ASPET) and the International Society for the Study of Xenobiotics (ISSX). He is the 2017 President-Elect of ASPET, and also Past Secretary/Treasurer. He also served ASPET as Chair of the Drug Metabolism and Disposition Division, and as a member of the Board of Publications Trustees. He was the Meeting Chair for the 17th North American meeting of ISSX in 2011. He was the Editor in Chief of Drug Metabolism and Disposition from 2012 to 2017 and is a former Associate Editor of Molecular Pharmacology. Dr. Morgan also served as a regular member on the Pharmacology and XNDA Study Sections of the NIH, and on the Pharmacology Test Committee of the National Board of Medical Examiners.

Dr. Morgan has a long-standing commitment to graduate student training, and was Director or DGS of the Molecular and Systems Pharmacology (MSP) graduate program from its inception in 1996 until 2012. He was also Director of Graduate Studies in Biochemistry and Molecular Biology (1990-94), and Physiological and Pharmacological Sciences (1994-96). He was the PI of Emorys T32 Training Grant in the Pharmacological Sciences (5T32GM008602-15) from 2004-2013.

Dr. Morgan is also committed to increasing the number of scientists in the workforce who are students from diverse backgrounds, including training students in his own lab, recruiting such students into Emory graduate programs, and providing matriculated students with the resources they need to be successful. He is currently Graduate Coordinator of Emorys NIH-funded Initiative for Maximizing Student Development (IMSD) program, and a founding member of the Atlanta Society of Mentors.

Academic Appointment

• Vice Chair for Academic Affairs, School of Medicine, Emory University
• Professor and Vice Chair, Pharmacology, Emory University

Education

Research