Edwin Horwitz
- SOM: Peds: BMT
Professor
-
Aflac Cancer and Blood Disorders Center
Pediatrics
2015 Uppergate Drive
Academic Appointment
- Professor of Pediatrics, Emory University
- Member, Immunology and Molecular Pathogenesis Program, Emory University Laney Graduate School Program
Education
Degrees
- PhD, Biochemistry from Indiana University
- MD from University of Indiana
- AB, Chemistry from Indiana University
Research
Publications
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ISCT MSC committee statement on the US FDA approval of allogenic bone-marrow mesenchymal stromal cells.
Cytotherapy Volume: 27 Page(s): 413 - 416
04/01/2025 Authors: Blanc KL; Dazzi F; English K; Farge D; Galipeau J; Horwitz EM; Kadri N; Krampera M; Lalu MM; Nolta J -
Delphi-driven consensus definition for mesenchymal stromal cells and clinical reporting guidelines for mesenchymal stromal cell-based therapeutics.
Cytotherapy Volume: 27 Page(s): 146 - 168
02/01/2025 Authors: Renesme L; Cobey KD; Lalu MM; Bubela T; Chinnadurai R; De Vos J; Dunbar R; Fergusson D; Freund D; Galipeau J -
Single-cell multiomics to advance cell therapy.
Cytotherapy Volume: 27 Page(s): 137 - 145
02/01/2025 Authors: Goss K; Horwitz EM -
Graph-Based 3-Dimensional Spatial Gene Neighborhood Networks of Single Cells in Gels and Tissues.
BME Front Volume: 6 Page(s): 0110
01/01/2025 Authors: Fang Z; Krusen K; Priest H; Wang M; Kim S; Sriram A; Yellanki A; Singh A; Horwitz E; Coskun AF -
Unanswered questions following reports of secondary malignancies after CAR-T cell therapy.
Nat Med Volume: 30 Page(s): 338 - 341
02/01/2024 Authors: Levine BL; Pasquini MC; Connolly JE; Porter DL; Gustafson MP; Boelens JJ; Horwitz EM; Grupp SA; Maus MV; Locke FL -
Directing the migration of serum-free, ex vivo-expanded V9V2 T cells.
Front Immunol Volume: 15 Page(s): 1331322
01/01/2024 Authors: Parwani KK; Branella GM; Burnham RE; Burnham AJ; Bustamante AYS; Foppiani EM; Knight KA; Petrich BG; Horwitz EM; Doering CB -
Mitochondrial metabolic flexibility is critical for CD8+ T cell antitumor immunity.
Sci Adv Volume: 9 Page(s): eadf9522
12/08/2023 Authors: Chen C; Zheng H; Horwitz EM; Ando S; Araki K; Zhao P; Li Z; Ford ML; Ahmed R; Qu C-K -
Differential response of mesenchymal stromal cells (MSCs) to type 1 ex vivo cytokine priming: implications for MSC therapy.
Cytotherapy Volume: 25 Page(s): 1277 - 1284
12/01/2023 Authors: Burnham AJ; Foppiani EM; Goss KL; Jang-Milligan F; Kamalakar A; Bradley H; Goudy SL; Trochez CM; Dominici M; Daley-Bauer L -
Short-Course Empiric Antibiotics in Children Undergoing Allogeneic Hematopoietic Cell Transplantation.
Transplant Cell Ther Volume: 29 Page(s): 778.e1 - 778.e6
12/01/2023 Authors: Patel PA; Teherani MF; Xiang Y; Bernardo V; Chandrakasan S; Goggin KP; Haight A; Horwitz E; Liang WH; Parikh SH -
Severe refractory hemorrhagic cystitis after hematopoietic cell transplantation responds to recombinant human keratinocyte growth factor-Case report and review of the literature.
Pediatr Blood Cancer Volume: 70 Page(s): e30606
10/01/2023 Authors: Hughes C; Harris A; Watkins B; Qayed M; Parikh S; Horwitz E; Stenger E; Williams KM; Schoettler ML -
Obesity-induced dysregulation of skin-resident PPAR+ Treg cells promotes IL-17A-mediated psoriatic inflammation.
Immunity Volume: 56 Page(s): 1844 - 1861.e6
08/08/2023 Authors: Sivasami P; Elkins C; Diaz-Saldana PP; Goss K; Peng A; Hamersky M; Bae J; Xu M; Pollack BP; Horwitz EM -
BCMA CAR-T induces complete and durable remission in refractory plasmablastic lymphoma.
J Immunother Cancer Volume: 11
05/01/2023 Authors: Raghunandan S; Pauly M; Blum WG; Qayed M; Dhodapkar MV; Elkhalifa M; Watkins B; Schoettler M; Horwitz E; Parikh S -
BCMA CAR-T AFTER ALLOGENEIC HCT INDUCES REMISSION IN REFRACTORY PLASMABLASTIC LYMPHOMA
Volume: 69
06/01/2022 Authors: Raghunandan S; Pauly M; Blum W; Qayed M; Dhodapkar M; Elkhalifa M; Watkins B; Schoettler M; Horwitz E; Parikh S -
Blinatumomab induces complete response in refractory PTLD after hematopoietic cell transplantation.
Blood Adv Volume: 6 Page(s): 3058 - 3061
05/24/2022 Authors: Janardan S; Horwitz E; Watkins B; Williams K; Chandrakasan S; Qayed M; Parikh S; Arnold S; Keller F; Alazraki A -
Culture Condition of Bone Marrow-Derived Stem/Stromal Cells Affects Quantity and Quality of the Extracellular Vesicles
Volume: 37 Page(s): 295 - 295
02/01/2022 Authors: Scheiber A; Clark C; Iwamoto M; Horwitz E; Imamura-Kawasawa Y; Otsuru S -
Culture Condition of Bone Marrow Stromal Cells Affects Quantity and Quality of the Extracellular Vesicles.
Int J Mol Sci Volume: 23
01/18/2022 Authors: Scheiber AL; Clark CA; Kaito T; Iwamoto M; Horwitz EM; Kawasawa YI; Otsuru S -
Survival Associations between Patient Age and Treatment Modality in Olfactory Neuroblastoma: A Retrospective Population-Based Study.
J Clin Med Volume: 10
06/18/2021 Authors: Burnham AJ; Burnham PA; Horwitz EM -
Splenic macrophage phagocytosis of intravenously infused mesenchymal stromal cells attenuates tumor localization.
Cytotherapy Volume: 23 Page(s): 411 - 422
05/01/2021 Authors: Hasgur S; Desbourdes L; Relation T; Overholt KM; Stanek JR; Guess AJ; Yu M; Patel P; Roback L; Dominici M -
Localized Sampling Enables Monitoring of Cell State via Inline Electrospray Ionization Mass Spectrometry.
Biotechnol J Volume: 16 Page(s): e2000277
03/01/2021 Authors: Chilmonczyk MA; Doron G; Kottke PA; Culberson AL; Leguineche K; Guldberg RE; Horwitz EM; Fedorov AG -
Mesenchymal stromal cells in hematopoietic cell transplantation.
Blood Adv Volume: 4 Page(s): 5877 - 5887
11/24/2020 Authors: Burnham AJ; Daley-Bauer LP; Horwitz EM -
Targeting GD2-positive glioblastoma by chimeric antigen receptor empowered mesenchymal progenitors.
Cancer Gene Ther Volume: 27 Page(s): 558 - 570
08/01/2020 Authors: Golinelli G; Grisendi G; Prapa M; Bestagno M; Spano C; Rossignoli F; Bambi F; Sardi I; Cellini M; Horwitz EM -
Probing MSC and Tumor Cell Secretome Locally via Dynamic Sampling Platform (DSP)
Volume: 22 Page(s): S14 - S15
05/01/2020 Authors: Chilmonczyk M; Kottke P; Horwitz E; Fedorov A -
Key Metabolic Pathways in MSC-Mediated Immunomodulation: Implications for the Prophylaxis and Treatment of Graft Versus Host Disease.
Front Immunol Volume: 11 Page(s): 609277
01/01/2020 Authors: Burnham AJ; Foppiani EM; Horwitz EM -
Combination of Interferon a, Delivered By Engineered Mesenchymal Stromal Cells, and Cytarabine Limits the Development of Acute Myeloid Leukemia, Potentially Targeting Leukemic Stem Cells
Volume: 134
11/13/2019 Authors: Laura DM; Hasgur S; Guess AJ; Yu M; Otsuru S; Horwitz EM -
Challenges in Clinical Development of Mesenchymal Stromal/Stem Cells: Concise Review.
Stem Cells Transl Med Volume: 8 Page(s): 1135 - 1148
11/01/2019 Authors: Mastrolia I; Foppiani EM; Murgia A; Candini O; Samarelli AV; Grisendi G; Veronesi E; Horwitz EM; Dominici M -
Impact of HOXB7 overexpression on human adipose-derived mesenchymal progenitors.
Stem Cell Res Ther Volume: 10 Page(s): 101
03/19/2019 Authors: Foppiani EM; Candini O; Mastrolia I; Murgia A; Grisendi G; Samarelli AV; Boscaini G; Pacchioni L; Pinelli M; De Santis G -
The Nationwide Children's Hospital BMT Index (BMTI): A Novel Quality Improvement Metric to Assess the Overall Performance of a Pediatric Blood and Marrow Transplant Program
Volume: 25
03/01/2019 Authors: Rangarajan HG; Moore J; Bajwa RPS; Olshefski R; Horwitz EM; Auletta JJ; Abu-Arja R -
Soluble TRAIL Armed Human MSC As Gene Therapy For Pancreatic Cancer.
Sci Rep Volume: 9 Page(s): 1788
02/11/2019 Authors: Spano C; Grisendi G; Golinelli G; Rossignoli F; Prapa M; Bestagno M; Candini O; Petrachi T; Recchia A; Miselli F -
Inducible Caspase9-mediated suicide gene for MSC-based cancer gene therapy.
Cancer Gene Ther Volume: 26 Page(s): 11 - 16
02/01/2019 Authors: Rossignoli F; Grisendi G; Spano C; Golinelli G; Recchia A; Rovesti G; Orsi G; Veronesi E; Horwitz EM; Dominici M -
MSC-Delivered Soluble TRAIL and Paclitaxel as Novel Combinatory Treatment for Pancreatic Adenocarcinoma.
Theranostics Volume: 9 Page(s): 436 - 448
01/01/2019 Authors: Rossignoli F; Spano C; Grisendi G; Foppiani EM; Golinelli G; Mastrolia I; Bestagno M; Candini O; Petrachi T; Recchia A -
Intratumoral Delivery of Interferon-Secreting Mesenchymal Stromal Cells Repolarizes Tumor-Associated Macrophages and Suppresses Neuroblastoma Proliferation In Vivo.
Stem Cells Volume: 36 Page(s): 915 - 924
06/01/2018 Authors: Relation T; Yi T; Guess AJ; La Perle K; Otsuru S; Hasgur S; Dominici M; Breuer C; Horwitz EM -
Clinical Indices Can Standardize and Monitor Pediatric Care: A Novel Mechanism to Improve Quality and Safety.
J Pediatr Volume: 193 Page(s): 190 - 195.e1
02/01/2018 Authors: Crandall W; Davis JT; Dotson J; Elmaraghy C; Fetzer M; Hayes D; Horwitz E; Kogon A; Olshefski R; Patel H -
Extracellular vesicles released from mesenchymal stromal cells stimulate bone growth in osteogenesis imperfecta.
Cytotherapy Volume: 20 Page(s): 62 - 73
01/01/2018 Authors: Otsuru S; Desbourdes L; Guess AJ; Hofmann TJ; Relation T; Kaito T; Dominici M; Iwamoto M; Horwitz EM -
Identification of a murine CD45-F4/80lo HSC-derived marrow endosteal cell associated with donor stem cell engraftment.
Blood Adv Volume: 1 Page(s): 2667 - 2678
12/26/2017 Authors: Overholt KM; Otsuru S; Olson TS; Guess AJ; Velazquez VM; Desbourdes L; Dominici M; Horwitz EM -
Identification of the Mechanism Underlying Growth Deficiency in Osteogenesis Imperfecta.
Volume: 32 Page(s): S117 - S117
12/01/2017 Authors: Otsuru S; Guess A; Cheah K; Iwamoto M; Horwitz E -
Contribution of Extra-Cardiac Cells in Murine Heart Valves is Age-Dependent.
J Am Heart Assoc Volume: 6
10/20/2017 Authors: Anstine LJ; Horne TE; Horwitz EM; Lincoln J -
Safety Profile of Good Manufacturing Practice Manufactured Interferon -Primed Mesenchymal Stem/Stromal Cells for Clinical Trials.
Stem Cells Transl Med Volume: 6 Page(s): 1868 - 1879
10/01/2017 Authors: Guess AJ; Daneault B; Wang R; Bradbury H; La Perle KMD; Fitch J; Hedrick SL; Hamelberg E; Astbury C; White P -
Severe transplant-associated thrombotic microangiopathy in patients with hemoglobinopathies.
Pediatr Blood Cancer Volume: 64
09/01/2017 Authors: Abusin GA; Abu-Arja R; Bajwa RPS; Horwitz EM; Auletta JJ; Rangarajan HG -
Concise Review: An (Im)Penetrable Shield: How the Tumor Microenvironment Protects Cancer Stem Cells.
Stem Cells Volume: 35 Page(s): 1123 - 1130
05/01/2017 Authors: Relation T; Dominici M; Horwitz EM -
Sickle cell disease: an international survey of results of HLA-identical sibling hematopoietic stem cell transplantation.
Blood Volume: 129 Page(s): 1548 - 1556
03/16/2017 Authors: Gluckman E; Cappelli B; Bernaudin F; Labopin M; Volt F; Carreras J; Pinto Simes B; Ferster A; Dupont S; de la Fuente J -
Health Care Utilization Costs Incurred during Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia in Children and Adolescent and Young Adults (AYA): A Comparative Study
Volume: 23 Page(s): S295 - S295
03/01/2017 Authors: Smith LC; Stanek J; O'Brien S; Abu-Arja R; Bajwa R; Horwitz EM; Auletta JJ; Lee D; Rangarajan HG -
Hematopoietic cell transplantation for a child with OSTM1 osteopetrosis.
Blood Adv Volume: 1 Page(s): 279 - 281
01/10/2017 Authors: Overholt KM; Rose MJ; Joshi S; Herman GE; Bajwa R; Abu-Arja R; Rangarajan HG; Horwitz EM -
Hematopoietic derived cells do not contribute to osteogenesis as osteoblasts.
Bone Volume: 94 Page(s): 1 - 9
01/01/2017 Authors: Otsuru S; Overholt KM; Olson TS; Hofmann TJ; Guess AJ; Velazquez VM; Kaito T; Dominici M; Horwitz EM -
Early Infection Attenuates Hematologic Malignant Disease Relapse Following Initial Allogeneic Hematopoietic Cell Transplantation
Volume: 128
12/02/2016 Authors: Auletta JJ; Ardura MI; Vasu S; Huang Y; Zhao Q; Ruppert AS; Shoben A; Elder P; Bingman A; Kitzler R -
Inactivated Mesenchymal Stem Cells Maintain Immunomodulatory Capacity.
Stem Cells Dev Volume: 25 Page(s): 1342 - 1354
09/15/2016 Authors: Luk F; de Witte SFH; Korevaar SS; Roemeling-van Rhijn M; Franquesa M; Strini T; van den Engel S; Gargesha M; Roy D; Dor FJMF -
Modulation of the immune system by secretome-deficient mesenchymal stem cells
Volume: 100 Page(s): S368 - S368
07/01/2016 Authors: Luk F; de Witte SFH; Korevaar SS; Roemeling-van Rhijn M; Franquesa M; Strini T; van den Engel S; Gargesha M; Roy D; Dor FJMF -
HEMATOPOIETIC CELL TRANSPLANTATION FOR CHILDREN WITH OSTM1-OSTEOPETROSIS: BRIEF REPORT
Volume: 63 Page(s): S14 - S14
06/01/2016 Authors: Overholt K; Rangarajan H; Joshi S; Rose M; Bajwa R; Abu-Arja R; Auletta J; Horwitz E -
SEVERE TRANSPLANT-ASSOCIATED THROMBOTIC MICROANGIOPATHY (TA-TMA) IN PATIENTS WITH HEMOGLOBINOPATHIES: A CASE SERIES
Volume: 63 Page(s): S95 - S95
06/01/2016 Authors: Rangarajan HG; Abusin GA; Bajwa R; Auletta JJ; Horwitz EM; Abu-Arja R -
The IncRNA HOTAIR is overexpressed in Ewing sarcoma and promotes malignant transformation through interactions with histone-modifying complexes
Volume: 76
03/15/2016 Authors: Siddiqui H; Selich-Taylor J; Felgenhauer J; Otsuru S; Horwitz E; Shah N -
70% Ethanol for Decontamination of Cvl Exposed to Calcineurine Inhibitors
Volume: 22 Page(s): S287 - S287
03/01/2016 Authors: Copacia JA; Taylor K; Laudick M; Abu-Arja R; Auletta JJ; Rangarajan HG; Horwitz EM; Stanek J; Pai VB; Bajwa R -
Tumor Stroma Manipulation By MSC.
Curr Drug Targets Volume: 17 Page(s): 1111 - 1126
01/01/2016 Authors: Grisendi G; Spano C; Rossignoli F; D Souza N; Golinelli G; Fiori A; Horwitz EM; Guarneri V; Piacentini F; Paolucci P -
Part 1: Defining unproven cellular therapies.
Cytotherapy Volume: 18 Page(s): 117 - 119
01/01/2016 Authors: Srivastava A; Mason C; Wagena E; Cuende N; Weiss DJ; Horwitz EM; Dominici M -
Anicteric veno-occlusive disease after hematopoietic stem cell transplantation in children.
Bone Marrow Transplant Volume: 51 Page(s): 135 - 137
01/01/2016 Authors: Naples JC; Skeens MA; Auletta J; Rangarajan H; Abu-Arja R; Horwitz E; Stanek J; Bajwa RS -
Adaptation of Marrow Osteoblast Morphology Mediated By a Hematopoietic-Derived Endosteal Cell Is Critical for Donor HSC Engraftment after BMT
Volume: 126
12/03/2015 Authors: Overholt K; Otsuru S; Best V; Guess A; Olson TS; Dominici M; Horwitz EM -
Positioning a Scientific Community on Unproven Cellular Therapies: The 2015 International Society for Cellular Therapy Perspective.
Cytotherapy Volume: 17 Page(s): 1663 - 1666
12/01/2015 Authors: Dominici M; Nichols K; Srivastava A; Weiss DJ; Eldridge P; Cuende N; Deans RJ; Rasko JEJ; Levine AD; Turner L -
Influence of Posttransplant Lymphoproliferative Disorder on Survival in Children After Heart Transplantation.
Pediatr Cardiol Volume: 36 Page(s): 1748 - 1753
12/01/2015 Authors: Hayes D; Breuer CK; Horwitz EM; Yates AR; Tobias JD; Shinoka T -
A novel anti-GD2/4-1BB chimeric antigen receptor triggers neuroblastoma cell killing.
Oncotarget Volume: 6 Page(s): 24884 - 24894
09/22/2015 Authors: Prapa M; Caldrer S; Spano C; Bestagno M; Golinelli G; Grisendi G; Petrachi T; Conte P; Horwitz EM; Campana D -
Mesenchymal stem/stromal cells as a delivery platform in cell and gene therapies.
BMC Med Volume: 13 Page(s): 186
08/12/2015 Authors: D'souza N; Rossignoli F; Golinelli G; Grisendi G; Spano C; Candini O; Osturu S; Catani F; Paolucci P; Horwitz EM -
Hematopoietic stem cell transplantation for infantile osteopetrosis.
Blood Volume: 126 Page(s): 270 - 276
07/09/2015 Authors: Orchard PJ; Fasth AL; Le Rademacher J; He W; Boelens JJ; Horwitz EM; Al-Seraihy A; Ayas M; Bonfim CM; Boulad F -
Detection of microparticles from human red blood cells by multiparametric flow cytometry.
Blood Transfus Volume: 13 Page(s): 274 - 280
04/01/2015 Authors: Grisendi G; Finetti E; Manganaro D; Cordova N; Montagnani G; Spano C; Prapa M; Guarneri V; Otsuru S; Horwitz EM -
Going back to class I: MHC and immunotherapies for childhood cancer.
Pediatr Blood Cancer Volume: 62 Page(s): 571 - 576
04/01/2015 Authors: Haworth KB; Leddon JL; Chen C-Y; Horwitz EM; Mackall CL; Cripe TP -
Mesenchymal progenitors expressing TRAIL induce apoptosis in sarcomas.
Stem Cells Volume: 33 Page(s): 859 - 869
03/01/2015 Authors: Grisendi G; Spano C; D'souza N; Rasini V; Veronesi E; Prapa M; Petrachi T; Piccinno S; Rossignoli F; Burns JS -
Mesenchymal progenitors aging highlights a miR-196 switch targeting HOXB7 as master regulator of proliferation and osteogenesis.
Stem Cells Volume: 33 Page(s): 939 - 950
03/01/2015 Authors: Candini O; Spano C; Murgia A; Grisendi G; Veronesi E; Piccinno MS; Ferracin M; Negrini M; Giacobbi F; Bambi F -
Genomic and functional comparison of mesenchymal stromal cells prepared using two isolation methods.
Cytotherapy Volume: 17 Page(s): 262 - 270
03/01/2015 Authors: Otsuru S; Hofmann TJ; Raman P; Olson TS; Guess AJ; Dominici M; Horwitz EM -
Expansion of the Endosteal Hematopoietic Stem Cell Niche Following Myeloablative and Reduced Intensity Conditioning Is Triggered By Hematopoietic Cell Loss
Volume: 124
12/06/2014 Authors: Olson TS; Otsuru S; Hofmann TJ; Dominici M; Horwitz EM -
Tendon progenitor cells in injured tendons have strong chondrogenic potential: the CD105-negative subpopulation induces chondrogenic degeneration.
Stem Cells Volume: 32 Page(s): 3266 - 3277
12/01/2014 Authors: Asai S; Otsuru S; Candela ME; Cantley L; Uchibe K; Hofmann TJ; Zhang K; Wapner KL; Soslowsky LJ; Horwitz EM -
MODIFIED ADIPOSE MESENCHYMAL PROGENITORS TARGET EWING'S SARCOMA
Volume: 34 Page(s): 5930 - 5931
10/01/2014 Authors: Grisendi G; Spano C; D'Souza N; Rasini V; Veronesi E; Piccinno S; De Santis G; Horwitz E; Conte P; Paolucci P -
EQUIVALENT MSC PREPARATIONS USING TWO ISOLATION METHODS
Volume: 16 Page(s): S75 - S75
04/01/2014 Authors: Otsuru S; Hofmann T; Raman P; Olson T; Horwitz E -
MICRORNA IN MICROVESICLES RELEASED FROM MSCS MEDIATES TROPHIC EFFECT
Volume: 16 Page(s): S74 - S74
04/01/2014 Authors: Otsuru S; Hofmann T; Horwitz E -
MODIFIED ADIPOSE MESENCHYMAL PROGENITORS TARGET EWING'S SARCOMA
Volume: 16 Page(s): S32 - S32
04/01/2014 Authors: Grisendi G; Spano C; D'Souza N; Rasini V; Veronesi E; Piccinno S; De Santis G; Horwitz E; Conte P; Paolucci P -
INTERNATIONAL STUDY ON OUTCOMES OF HAEMATOPOIETIC STEM CELL TRANSPLANT FOR DNA-DSB REPAIR DEFECTS.
Volume: 49 Page(s): S375 - S375
03/01/2014 Authors: Slack J; Slatter MA; Gaspar B; Albert M; Ghosh S; Meisel R; Guengoer T; Karasu G; Drabko K; Lange A -
Oncolytic virotherapy for ALL: MSCs to the rescue.
Blood Volume: 123 Page(s): 1286 - 1287
02/27/2014 Authors: Horwitz EM -
Effect of postremission therapy before reduced-intensity conditioning allogeneic transplantation for acute myeloid leukemia in first complete remission.
Biol Blood Marrow Transplant Volume: 20 Page(s): 202 - 208
02/01/2014 Authors: Warlick ED; Paulson K; Brazauskas R; Zhong X; Miller AM; Camitta BM; George B; Savani BN; Ustun C; Marks DI -
Delayed marrow infusion in mice enhances hematopoietic and osteopoietic engraftment by facilitating transient expansion of the osteoblastic niche.
Biol Blood Marrow Transplant Volume: 19 Page(s): 1566 - 1573
11/01/2013 Authors: Marino R; Otsuru S; Hofmann TJ; Olson TS; Rasini V; Veronesi E; Boyd K; Gaber MW; Martinez C; Paolucci P -
IGF-1-mediated osteoblastic niche expansion enhances long-term hematopoietic stem cell engraftment after murine bone marrow transplantation.
Stem Cells Volume: 31 Page(s): 2193 - 2204
10/01/2013 Authors: Caselli A; Olson TS; Otsuru S; Chen X; Hofmann TJ; Nah H-D; Grisendi G; Paolucci P; Dominici M; Horwitz EM -
Adipose stromal/stem cells assist fat transplantation reducing necrosis and increasing graft performance.
Apoptosis Volume: 18 Page(s): 1274 - 1289
10/01/2013 Authors: Piccinno MS; Veronesi E; Loschi P; Pignatti M; Murgia A; Grisendi G; Castelli I; Bernabei D; Candini O; Conte P -
Frequent mutations in SH2D1A (XLP) in males presenting with high-grade mature B-cell neoplasms.
Pediatr Blood Cancer Volume: 60 Page(s): E85 - E87
09/01/2013 Authors: Sandlund JT; Shurtleff SA; Onciu M; Horwitz E; Leung W; Howard V; Rencher R; Conley ME -
Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning.
Blood Volume: 121 Page(s): 5238 - 5249
06/27/2013 Authors: Olson TS; Caselli A; Otsuru S; Hofmann TJ; Williams R; Paolucci P; Dominici M; Horwitz EM -
Transplanted murine long-term repopulating hematopoietic cells can differentiate to osteoblasts in the marrow stem cell niche.
Mol Ther Volume: 21 Page(s): 1224 - 1231
06/01/2013 Authors: Hofmann TJ; Otsuru S; Marino R; Rasini V; Veronesi E; Murgia A; Lahti J; Boyd K; Dominici M; Horwitz EM -
Outcomes of transplantation using various hematopoietic cell sources in children with Hurler syndrome after myeloablative conditioning.
Blood Volume: 121 Page(s): 3981 - 3987
05/09/2013 Authors: Boelens JJ; Aldenhoven M; Purtill D; Ruggeri A; Defor T; Wynn R; Wraith E; Cavazzana-Calvo M; Rovelli A; Fischer A -
Manufacturing mesenchymal stromal cells for phase I clinical trials.
Cytotherapy Volume: 15 Page(s): 416 - 422
04/01/2013 Authors: Hanley PJ; Mei Z; da Graca Cabreira-Hansen M; Klis M; Li W; Zhao Y; Durett AG; Zheng X; Wang Y; Gee AP -
Advancing regenerative medicine the translational way.
Sci Transl Med Volume: 5 Page(s): 177fs9
03/20/2013 Authors: Horwitz EM -
Improved isolation and expansion of bone marrow mesenchymal stromal cells using a novel marrow filter device.
Cytotherapy Volume: 15 Page(s): 146 - 153
02/01/2013 Authors: Otsuru S; Hofmann TJ; Olson TS; Dominici M; Horwitz EM -
A phase I/II study of CY and topotecan in patients with high-risk malignancies undergoing autologous hematopoietic cell transplantation: the St Jude long-term follow-up.
Bone Marrow Transplant Volume: 47 Page(s): 1448 - 1454
11/01/2012 Authors: Kasow KA; Stewart CF; Barfield RC; Wright NL; Li C; Srivastava DK; Leung W; Horwitz EM; Bowman LC; Handgretinger R -
Long-term survival and late deaths after hematopoietic cell transplantation for primary immunodeficiency diseases and inborn errors of metabolism.
Biol Blood Marrow Transplant Volume: 18 Page(s): 1438 - 1445
09/01/2012 Authors: Eapen M; Ahn KW; Orchard PJ; Cowan MJ; Davies SM; Fasth A; Hassebroek A; Ayas M; Bonfim C; O'Brien TA -
Transplanted bone marrow mononuclear cells and MSCs impart clinical benefit to children with osteogenesis imperfecta through different mechanisms.
Blood Volume: 120 Page(s): 1933 - 1941
08/30/2012 Authors: Otsuru S; Gordon PL; Shimono K; Jethva R; Marino R; Phillips CL; Hofmann TJ; Veronesi E; Dominici M; Iwamoto M -
Malignancies after hematopoietic cell transplantation for primary immune deficiencies: a report from the Center for International Blood and Marrow Transplant Research.
Biol Blood Marrow Transplant Volume: 17 Page(s): 1783 - 1789
12/01/2011 Authors: Kamani NR; Kumar S; Hassebroek A; Eapen M; LeRademacher J; Casper J; Cowan M; Snchez de Toledo J; Ferster A; Szabolcs P -
Statins are active in acute lymphoblastic leukaemia (ALL): a therapy that may treat ALL and prevent avascular necrosis.
Br J Haematol Volume: 155 Page(s): 403 - 407
11/01/2011 Authors: Sheen C; Vincent T; Barrett D; Horwitz EM; Hulitt J; Strong E; Grupp SA; Teachey DT -
Cytokine-induced osteopoietic differentiation of transplanted marrow cells.
Blood Volume: 118 Page(s): 2358 - 2361
08/25/2011 Authors: Otsuru S; Rasini V; Bussolari R; Hofmann TJ; Dominici M; Horwitz EM -
TRAVEL STIPEND AWARD WINNER HOST-DERIVED MEGAKARYOCYTES ENABLE EFFICIENT HEMATOPOIETIC STEM CELL ENGRAFTMENT FOLLOWING RADIOABLATION THROUGH FACILITATION OF OSTEOBLASTIC STEM CELL NICHE EXPANSION
Volume: 56 Page(s): 898 - 898
06/01/2011 Authors: Olson T; Caselli A; Otsuru S; Hofmann T; Horwitz E -
Institutional profile. The International Society for Cellular Therapy: evolving to meet the demands of the regenerative medicine industry.
Regen Med Volume: 6 Page(s): 163 - 166
03/01/2011 Authors: Maziarz RT; Arthurs J; Horwitz E -
Clinical outcomes following hematopoietic stem cell transplantation for the treatment of mucopolysaccharidosis VI.
Mol Genet Metab Volume: 102 Page(s): 111 - 115
02/01/2011 Authors: Turbeville S; Nicely H; Rizzo JD; Pedersen TL; Orchard PJ; Horwitz ME; Horwitz EM; Veys P; Bonfim C; Al-Seraihy A -
Guidance for developing phase II cell therapy trial proposals for consideration by the Blood and Marrow Transplant Clinical Trials Network.
Biol Blood Marrow Transplant Volume: 17 Page(s): 192 - 196
02/01/2011 Authors: Horwitz EM; Horowitz MM; DiFronzo NL; Kohn DB; Heslop HE; Blood and Marrow Transplant Clinical Trials Network, State of the Science Cell and Gene Therapy Committee -
Focusing on the Borders Between Bone and Blood to Better Understand Stem Cells Based Regeneration
Volume: 17 Page(s): 540 - 541
02/01/2011 Authors: Dominici M; Rasini V; Veronesi E; Piccinno S; Bussolari R; Conte P; Paolucci P; Horwitz E -
Understanding tumor-stroma interplays for targeted therapies by armed mesenchymal stromal progenitors: the Mesenkillers.
Am J Cancer Res Volume: 1 Page(s): 787 - 805
01/01/2011 Authors: Grisendi G; Bussolari R; Veronesi E; Piccinno S; Burns JS; De Santis G; Loschi P; Pignatti M; Di Benedetto F; Ballarin R -
MSCs in hematopoietic cell transplantation.
Biol Blood Marrow Transplant Volume: 17 Page(s): S21 - S29
01/01/2011 Authors: Horwitz EM; Maziarz RT; Kebriaei P -
Cell therapy medical tourism: time for action.
Cytotherapy Volume: 12 Page(s): 965 - 968
12/01/2010 Authors: Gunter KC; Caplan AL; Mason C; Salzman R; Janssen WE; Nichols K; Bouzas LF; Lanza F; Levine BL; Rasko JEJ -
Building bone from blood vessels.
Nat Med Volume: 16 Page(s): 1373 - 1374
12/01/2010 Authors: Horwitz EM -
A strategy for single nucleotide polymorphism analysis of chimerism for somatic cell therapy.
Cytotherapy Volume: 12 Page(s): 1035 - 1043
12/01/2010 Authors: Chen X; Hofmann TJ; Otsuru S; Jethva R; Lind C; Monos D; Horwitz EM -
Novel Role for Host-Derived Megakaryocytes In Facilitating Stem Cell Engraftment through Enhancement of Osteoblastic Niche Restoration Following Radioablation
Volume: 116 Page(s): 247 - 247
11/19/2010 Authors: Olson TS; Caselli A; Otsuru S; Hofmann T; Horwitz EM -
Advancement of pediatric blood and marrow transplantation research in North America: priorities of the Pediatric Blood and Marrow Transplant Consortium.
Biol Blood Marrow Transplant Volume: 16 Page(s): 1212 - 1221
09/01/2010 Authors: Pulsipher MA; Horwitz EM; Haight AE; Kadota R; Chen AR; Frangoul H; Cooper LJN; Jacobsohn DA; Goyal RK; Mitchell D -
Osteopoietic engraftment after bone marrow transplantation: effect of inbred strain of mice.
Exp Hematol Volume: 38 Page(s): 836 - 844
09/01/2010 Authors: Otsuru S; Hofmann TJ; Rasini V; Veronesi E; Dominici M; Horwitz EM -
Getting beneath the skin to understand MSC complexity.
Cytotherapy Volume: 12 Page(s): 438 - 439
07/01/2010 Authors: Dominici M; Horwitz EM -
GMP-manufactured density gradient media for optimized mesenchymal stromal/stem cell isolation and expansion.
Cytotherapy Volume: 12 Page(s): 466 - 477
07/01/2010 Authors: Grisendi G; Annern C; Cafarelli L; Sternieri R; Veronesi E; Cervo GL; Luminari S; Maur M; Frassoldati A; Palazzi G -
Adipose-derived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapy.
Cancer Res Volume: 70 Page(s): 3718 - 3729
05/01/2010 Authors: Grisendi G; Bussolari R; Cafarelli L; Petak I; Rasini V; Veronesi E; De Santis G; Spano C; Tagliazzucchi M; Barti-Juhasz H -
Parabiotic heterogenetic pairing of Abcc6-/-/Rag1-/- mice and their wild-type counterparts halts ectopic mineralization in a murine model of pseudoxanthoma elasticum.
Am J Pathol Volume: 176 Page(s): 1855 - 1862
04/01/2010 Authors: Jiang Q; Oldenburg R; Otsuru S; Grand-Pierre AE; Horwitz EM; Uitto J -
Molecular and clinical heterogeneity in CLCN7-dependent osteopetrosis: report of 20 novel mutations.
Hum Mutat Volume: 31 Page(s): E1071 - E1080
01/01/2010 Authors: Pangrazio A; Pusch M; Caldana E; Frattini A; Lanino E; Tamhankar PM; Phadke S; Lopez AGM; Orchard P; Mihci E -
Long-Term Survival and Late Deaths After Hematopoietic Stem Cell Transplantation for Primary Immunodeficiency Diseases and Inborn Errors of Metabolism
Volume: 114 Page(s): 1287 - 1288
11/20/2009 Authors: Eapen M; Ahn KW; Orchard P; Cowan MJ; Davies SM; Fasth A; Hassebroek A; Ayas MF; Bonfim C; O'Brien T -
Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation.
Blood Volume: 114 Page(s): 2333 - 2343
09/10/2009 Authors: Dominici M; Rasini V; Bussolari R; Chen X; Hofmann TJ; Spano C; Bernabei D; Veronesi E; Bertoni F; Paolucci P -
Effects of activating NK cell receptor expression and NK cell reconstitution on the outcomes of unrelated donor hematopoietic cell transplantation for hematologic malignancies.
Leukemia Volume: 23 Page(s): 1278 - 1287
07/01/2009 Authors: Triplett BM; Horwitz EM; Iyengar R; Turner V; Holladay MS; Gan K; Behm FG; Leung W -
Heterogeneity of multipotent mesenchymal stromal cells: from stromal cells to stem cells and vice versa.
Volume: 87 Page(s): S36 - S42
05/15/2009 Authors: Dominici M; Paolucci P; Conte P; Horwitz EM -
Cytokines as the major mechanism of mesenchymal stem cell clinical activity: expanding the spectrum of cell therapy.
Isr Med Assoc J Volume: 11 Page(s): 209 - 211
04/01/2009 Authors: Horwitz EM; Prather WR -
Parabiotic heterogenetic pairing of Abcc6(-/-) and wild-type mice halts progression of ectopic mineralization in a murine model of pseudoxanthoma elasticum
Volume: 129 Page(s): S84 - S84
04/01/2009 Authors: Jiang Q; Oldenburg R; Otsuru S; Grand-Pierre A; Horwitz EM; Uitto J -
Clinical utility of computed tomography screening of chest, abdomen, and sinuses before hematopoietic stem cell transplantation: the St. Jude experience.
Biol Blood Marrow Transplant Volume: 15 Page(s): 490 - 495
04/01/2009 Authors: Kasow KA; Krueger J; Srivastava DK; Li C; Barfield R; Leung W; Horwitz EM; Madden R; Woodard P; Hussain I -
A novel approach for quantification of KIR expression in healthy donors and pediatric recipients of hematopoietic SCTs.
Bone Marrow Transplant Volume: 43 Page(s): 525 - 532
04/01/2009 Authors: Chen X; Knowles J; Barfield RC; Kasow KA; Madden R; Woodard P; Srivastava DK; Horwitz EM; Handgretinger R; Hale GA -
SURVIVAL FOLLOWING ALLOGENEIC STEM CELL TRANSPLANTATION FOR CONGENITAL IMMUNODEFICIENCY AND METABOLIC DISORDERS
Volume: 15 Page(s): 78 - 78
02/01/2009 Authors: Horwitz ME; da Silva TG; Eapen M; Horwitz EM -
A PHASE I/II STUDY OF CYCLOPHOSPHAMIDE AND TOPOTECAN IN PATIENTS WITH HIGH-RISK MALIGNANCIES UNDERGOING AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION: THE ST. JUDE LONG-TERM FOLLOW-UP
Volume: 15 Page(s): 72 - 73
02/01/2009 Authors: Kasow KA; Barfield RC; Wrigbt NL; Li C; Srivastava DK; Horwitz EM; Leung W; Woodard P; Bowman LC; Handgretinger R -
FAVORABLE OUTCOMES IN PATIENTS WITH MALIGNANT INFANTILE OSTEOPETROSIS FOLLOWING HAPLOIDENTICAL TRANSPLANTATION USING A REDUCED INTENSITY PREPARATIVE REGIMEN
Volume: 15 Page(s): 25 - 25
02/01/2009 Authors: Kasov KA; Kaste SC; Lovins R; Wright NL; Leung W; Hale GA; Horwitz EM -
A STRATEGY FOR DISTINGUISHING SNP IDENTITY IN MULTIPLE-DONORS INVOLVED IN HAPLOIDENTICAL BONE MARROW TRANSPLANTATION
Volume: 15 Page(s): 99 - 99
02/01/2009 Authors: Chen X; Hofmann TJ; Otsuru S; Jethva R; Horwitz EM -
Total and active rabbit antithymocyte globulin (rATG;Thymoglobulin) pharmacokinetics in pediatric patients undergoing unrelated donor bone marrow transplantation.
Biol Blood Marrow Transplant Volume: 15 Page(s): 274 - 278
02/01/2009 Authors: Call SK; Kasow KA; Barfield R; Madden R; Leung W; Horwitz E; Woodard P; Panetta JC; Baker S; Handgretinger R -
Cell therapy for disorders of bone.
Cytotherapy Volume: 11 Page(s): 3 - 17
01/01/2009 Authors: Jethva R; Otsuru S; Dominici M; Horwitz EM -
Basic research and clinical applications of non-hematopoietic stem cells, 4-5 April 2008, Tubingen, Germany.
Cytotherapy Volume: 11 Page(s): 245 - 255
01/01/2009 Authors: Schfer R; Dominici M; Mller I; Horwitz E; Asahara T; Bulte JWM; Bieback K; Le Blanc K; Bhring HJ; Capogrossi MC -
Culture conditions shape mesenchymal stromal cell phenotype and function.
Cytotherapy Volume: 11 Page(s): 101 - 102
01/01/2009 Authors: Horwitz EM -
The role of placental-derived adherent stromal cell (PLX-PAD) in the treatment of critical limb ischemia.
Cytotherapy Volume: 11 Page(s): 427 - 434
01/01/2009 Authors: Prather WR; Toren A; Meiron M; Ofir R; Tschope C; Horwitz EM -
Donor cell-derived osteopoiesis originates from a self-renewing stem cell with a limited regenerative contribution after transplantation.
Blood Volume: 111 Page(s): 4386 - 4391
04/15/2008 Authors: Dominici M; Marino R; Rasini V; Spano C; Paolucci P; Conte P; Hofmann TJ; Horwitz EM -
Airway evaluation and management in 7 children with malignant infantile osteopetrosis before hematopoietic stem cell transplantation.
J Pediatr Hematol Oncol Volume: 30 Page(s): 225 - 229
03/01/2008 Authors: Kasow KA; Stocks RMS; Kaste SC; Donepudi S; Tottenham D; Schoumacher RA; Horwitz EM -
Transplantable marrow osteoprogenitors engraft in discrete saturable sites in the marrow microenvironment.
Exp Hematol Volume: 36 Page(s): 360 - 368
03/01/2008 Authors: Marino R; Martinez C; Boyd K; Dominici M; Hofmann TJ; Horwitz EM -
RABBIT ATG (THYMOGLOBULIN R) PHARMACOKINETICS IN PEDIATRIC PATIENTS RECEIVING A MATCHED UNRELATED DONOR BONE MARROW TRANSPLANTATION
Volume: 14 Page(s): 166 - 167
02/01/2008 Authors: Call SK; Kasow K; Barfield R; Leung W; Madden R; Horwitz E; Woodard P; Yusuf U; Panetta JC; Baker S -
How do mesenchymal stromal cells exert their therapeutic benefit?
Cytotherapy Volume: 10 Page(s): 771 - 774
01/01/2008 Authors: Horwitz EM; Dominici M -
Mesenchymal stromal cells moving forward.
Cytotherapy Volume: 10 Page(s): 5 - 6
01/01/2008 Authors: Horwitz EM -
A potential role for Dkk-1 in the pathogenesis of osteosarcoma predicts novel diagnostic and treatment strategies.
Br J Cancer Volume: 97 Page(s): 1552 - 1559
12/03/2007 Authors: Lee N; Smolarz AJ; Olson S; David O; Reiser J; Kutner R; Daw NC; Prockop DJ; Horwitz EM; Gregory CA -
0.1 grams of sub-cutaneous adipose tissue (SCAT) as source of adult multipotent mesenchymal stromal cells (MSC) for cell-based therapies
Volume: 110 Page(s): 304B - 304B
11/16/2007 Authors: Dominici M; Sternieri R; De Fazio D; Cafarelli L; Guaraldi G; Spano C; Rasini V; Paolucci P; Cilli M; Piccardi F -
3D grown human placental-derived mesenchymal stromal cells (PLX-I) support and potentiate the engraftment of human cord blood unfractionated (UFCBC) and fractionated CD34+cells (hCD34+) in irradiated NOD/SCID mice
Volume: 110 Page(s): 95B - 95B
11/16/2007 Authors: Burger O; Jacov OM; Carmi ND; Ashtamker GF; Pinzur L; Mizrachi E; Rusanovsky M; Bercovich N; Moshe OB; Lior L -
Human placental derived mesenchymal stromal cells (MSC) grown in 3D-culture (PLX-I), promotes engraftment of human umbilical cord blood (hUCB) derived CD34+cells in NOD/SCID mice
Volume: 110 Page(s): 424A - 424A
11/16/2007 Authors: Burger O; Ashtamker GF; Bercovich N; Rusanovsky M; Pinzur L; Jacov OM; Carmi ND; Meiron M; Lior L; Meretzki S -
GD2+selected mesenchymal stromal cells (MSCs) demonstrate a more robust proliferation and differentiation potential compared to unselected cells
Volume: 110 Page(s): 570A - 570A
11/16/2007 Authors: Martinez C; Hofmann TJ; Marino R; Dominici M; Horwitz EM -
EBV lymphoproliferative disease of host origin after haploidentical stem cell transplantation.
Pediatr Blood Cancer Volume: 49 Page(s): 869 - 872
11/01/2007 Authors: Kasow KA; Leung W; Horwitz EM; Woodard P; Handgretinger R; Hale GA -
Diagnostic yield of bronchoalveolar lavage is low in allogeneic hematopoietic stem cell recipients receiving immunosuppressive therapy or with acute graft-versus-host disease: the St. Jude experience, 1990-2002.
Biol Blood Marrow Transplant Volume: 13 Page(s): 831 - 837
07/01/2007 Authors: Kasow KA; King E; Rochester R; Tong X; Srivastava DK; Horwitz EM; Leung W; Woodard P; Handgretinger R; Hale GA -
Hematopoietic stem cell transplantaton for osteopetrosis
Volume: 92 Page(s): 133 - 133
06/01/2007 Authors: Orchard PJ; Eapen M; Tolar J; Horwitz E; Veys P; Fasth F -
Human bone marrow mesenchymal stromal cells express the neural ganglioside GD2: a novel surface marker for the identification of MSCs.
Blood Volume: 109 Page(s): 4245 - 4248
05/15/2007 Authors: Martinez C; Hofmann TJ; Marino R; Dominici M; Horwitz EM -
Comprehensive airway evaluation and management in children with malignant infantile osteopetrosis
Volume: 39 Page(s): S192 - S193
04/01/2007 Authors: Kasow K; Stocks RM; Kaste S; Schoumacher R; Horwitz E -
Report on the workshop "New Technologies in Stem Cell Research," Society for Pediatric Research, San Francisco, California, April 29, 2006.
Volume: 25 Page(s): 1070 - 1088
04/01/2007 Authors: Cheng JC; Horwitz EM; Karsten SL; Shoemaker L; Kornblum HI; Malik P; Sakamoto KM -
Long-term follow up of T cell depleted transplants from unrelated donors in pediatric patients
Volume: 13 Page(s): 18 - 18
02/01/2007 Authors: Hale GA; Krance RA; Khan SP; Rochester R; Horwitz EM; Turner V; Gee AP; Brenner MK; Heslop HE -
Quantitative bone mineral density assessment in malignant infantile osteopetrosis.
Pediatr Blood Cancer Volume: 48 Page(s): 181 - 185
02/01/2007 Authors: Kaste SC; Kasow KA; Horwitz EM -
Outcome of hematopoietic stem cell transplantation for pediatric patients with therapy-related acute myeloid leukemia or myelodysplastic syndrome.
Pediatr Blood Cancer Volume: 47 Page(s): 931 - 935
12/01/2006 Authors: Woodard P; Barfield R; Hale G; Horwitz E; Leung W; Ribeiro R; Rubnitz J; Srivistava DK; Tong X; Yusuf U -
Rapid immune reconstitution after a reduced-intensity conditioning regimen and a CD3-Depleted haploidentical stem cell graft for pediatric refractory hematologic malignancies.
Volume: 108 Page(s): 420B - 420B
11/16/2006 Authors: Chen X; Hale GA; Barfield RC; Benaim E; Leung WH; Knowles J; Horwitz EM; Woodard P; Kasow KA; Yusuf U -
Mismatched family member donor transplantation for patients with refractory hematologic malignancies: Long-term followup of a prospective clinical trial.
Volume: 108 Page(s): 895A - 895A
11/16/2006 Authors: Hale GA; Kasow KA; Madden R; Yusuf U; Horwitz E; Barfield R; Woodard J; Leung WH; Srivastava K; Handgretinger R -
High dose defibrofide as therapy for pediatric patients with veno-occlusive disease of the liver.
Volume: 108 Page(s): 840A - 840A
11/16/2006 Authors: Hale GA; Madden RM; Kasow KA; Woodard J; Leung WH; Barfield RC; Yusuf U; Horwitz EM; Handgretinger R -
Rapid immune reconstitution after a reduced-intensity conditioning regimen and a CD3-depleted haploidentical stem cell graft for paediatric refractory haematological malignancies.
Br J Haematol Volume: 135 Page(s): 524 - 532
11/01/2006 Authors: Chen X; Hale GA; Barfield R; Benaim E; Leung WH; Knowles J; Horwitz EM; Woodard P; Kasow K; Yusuf U -
Cidofovir for the treatment of adenoviral infection in pediatric hematopoietic stem cell transplant patients.
Transplantation Volume: 81 Page(s): 1398 - 1404
05/27/2006 Authors: Yusuf U; Hale GA; Carr J; Gu Z; Benaim E; Woodard P; Kasow KA; Horwitz EM; Leung W; Srivastava DK -
Skeletons in the p53 tumor suppressor closet: genetic evidence that p53 blocks bone differentiation and development.
J Cell Biol Volume: 172 Page(s): 795 - 797
03/13/2006 Authors: Zambetti GP; Horwitz EM; Schipani E -
Haploidentical transplantation for children with refractory haematologic malignancies
Volume: 37 Page(s): S250 - S250
03/01/2006 Authors: Hale G; Chen X; Benaim E; Woodard P; Kasow K; Horwitz E; Leung W; Yusuf U; Barfield R; Hayden R -
Acute graft-versus-host disease and immunosuppressive therapy identify patients less likely to have a diagnostic yield with a bronchoalveolar lavage: The St. Jude experience 1990-2002
Volume: 12 Page(s): 134 - 135
02/01/2006 Authors: Kasow KA; King E; Rochester RJ; Tong X; Srivastava DK; Horwitz EM; Leung W; Woodard P; Handgretinger R; Hale GA -
A review of the use of topotecan for mobilization of peripheral blood stem cells in autologous hematopoietic stem cell transplantation
Volume: 12 Page(s): 100 - 100
02/01/2006 Authors: Pring K; Hale G; Barfield R; Horwitz E; Kasow K; Leung W; Woodard P; Yusuf U; Handgretinger R -
Rabbit anti-thymocyte globulin (rATG; thymoglobulin (R)) pharmacokinetics in pediatric patients receiving a hematopoietic stem cell transplant (HSCT)
Volume: 12 Page(s): 171 - 171
02/01/2006 Authors: Hale GA; Call SK; Handgretinger R; Horwitz E; Kasow K; Barfield R; Yusuf U; Woodward P; Leung W; Rodman J -
Human MSCs express the neuronal ganglioside, GD2.
Volume: 8
01/01/2006 Authors: Martinez C; Hofmann T; Marino R; Horwitz EM -
Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement.
Cytotherapy Volume: 8 Page(s): 315 - 317
01/01/2006 Authors: Dominici M; Le Blanc K; Mueller I; Slaper-Cortenbach I; Marini F; Krause D; Deans R; Keating A; Prockop D; Horwitz E -
MSC: a coming of age in regenerative medicine.
Cytotherapy Volume: 8 Page(s): 194 - 195
01/01/2006 Authors: Horwitz EM -
Animal serum-free culture conditions for isolation and expansion of multipotent mesenchymal stromal cells from human BM.
Cytotherapy Volume: 8 Page(s): 437 - 444
01/01/2006 Authors: Mller I; Kordowich S; Holzwarth C; Spano C; Isensee G; Staiber A; Viebahn S; Gieseke F; Langer H; Gawaz MP -
Preliminary experience with haploidentical stem cell transplantation for children with sickle cell disease and stroke.
Volume: 106 Page(s): 445B - 445B
11/16/2005 Authors: Woodard J; Wang W; Barfield R; Hale G; Horwitz E; Leung W; Yusuf U; Ware R; Handgretinger R; Cunningham JM -
CD3 depleted hematopoietic peripheral blood stem cell grafts in children with refractory hematologic malignancies undergoing transplantation from mismatched related donors.
Volume: 106 Page(s): 451B - 451B
11/16/2005 Authors: Hale GA; Kasow KA; Lovins R; Woodard JP; Leung WH; Yusuf U; Horwitz EM; Srivastava DK; Tong X; Benaim E -
Haploidentical stem cell transplantation with CD3 depleted mobilized peripheral blood stem cell grafts for children with hematologic malignancies
Volume: 106 Page(s): 816A - 816A
11/16/2005 Authors: Hale GA; Kasow KA; Gan K; Horwitz E; Woodard JP; Yusuf U; Barfield R; Leung WH; Srivastava DK; Handgretinger R -
Hemolytic uremic syndrome after bone marrow transplantation: clinical characteristics and outcome in children.
Biol Blood Marrow Transplant Volume: 11 Page(s): 912 - 920
11/01/2005 Authors: Hale GA; Bowman LC; Rochester RJ; Benaim E; Heslop HE; Krance RA; Horwitz EM; Cunningham JM; Tong X; Srivastava DK -
Correction of a mineralization defect by overexpression of a wild-type cDNA for COL1A1 in marrow stromal cells (MSCs) from a patient with osteogenesis imperfecta: a strategy for rescuing mutations that produce dominant-negative protein defects.
Gene Ther Volume: 12 Page(s): 1119 - 1125
07/01/2005 Authors: Pochampally RR; Horwitz EM; DiGirolamo CM; Stokes DS; Prockop DJ -
Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta.
Transplantation Volume: 79 Page(s): 1607 - 1614
06/15/2005 Authors: Le Blanc K; Gtherstrm C; Ringdn O; Hassan M; McMahon R; Horwitz E; Anneren G; Axelsson O; Nunn J; Ewald U -
Transgenic mice with pancellular enhanced green fluorescent protein expression in primitive hematopoietic cells and all blood cell progeny.
Genesis Volume: 42 Page(s): 17 - 22
05/01/2005 Authors: Dominici M; Tadjali M; Kepes S; Allay ER; Boyd K; Ney PA; Horwitz E; Persons DA -
Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement.
Cytotherapy Volume: 7 Page(s): 393 - 395
01/01/2005 Authors: Horwitz EM; Le Blanc K; Dominici M; Mueller I; Slaper-Cortenbach I; Marini FC; Deans RJ; Krause DS; Keating A; International Society for Cellular Therapy -
CD133(+) hematopoietic cells successfully reconstitute hematopoiesis following autologous peripheral blood stem cell transplantation.
Volume: 104 Page(s): 130A - 130A
11/16/2004 Authors: Hale GA; Horwitz E; Leung W; Woodard P; Eldridge P; Yusuf U; Benaim E; Kasow K; Srivastava K; Handgretinger R -
Reduced-intensity conditioning (RIC) in haploidentical transplantation.
Volume: 104 Page(s): 590A - 591A
11/16/2004 Authors: Benaim E; Hale G; Horwitz E; Leung W; Woodard P; Yusuf U; Handgretinger R -
Isolation and expansion of functional differentiating mesenchymal stem cells with a serum deprived medium.
Volume: 104 Page(s): 779A - 780A
11/16/2004 Authors: Dominici M; Mueller I; Cafarelli L; Kordowich S; Sternieri R; Spano C; Chiodino C; Mariotti I; Petak I; Horwitz E -
Cidofovir is safe and effective in the treatment of adenoviral infection in pediatric hematopoietic stem cell transplantation.
Volume: 104 Page(s): 613A - 614A
11/16/2004 Authors: Yusuf U; Hale G; Woodard P; Benaim E; Kasow K; Horwitz E; Leung W; Srivastava D; Handgretinger R; Haden R -
Early kinetics of bone marrow cell engraftment in bone after transplantation: Insights into the mechanism of engraftment.
Volume: 104 Page(s): 365A - 365A
11/16/2004 Authors: Garlits JE; Dominici M; Hofmann TJ; Horwitz EM -
Hematopoietic cells and osteoblasts are derived from a common marrow progenitor after bone marrow transplantation.
Proc Natl Acad Sci U S A Volume: 101 Page(s): 11761 - 11766
08/10/2004 Authors: Dominici M; Pritchard C; Garlits JE; Hofmann TJ; Persons DA; Horwitz EM -
Dkk-1-mediated expansion of adult stem cells.
Trends Biotechnol Volume: 22 Page(s): 386 - 388
08/01/2004 Authors: Horwitz EM -
Cyclophosphamide and targeted dose topotecan with autologous hematopoietic stem cell rescue for solid tumors.
Volume: 22 Page(s): 807S - 807S
07/15/2004 Authors: Hale G; Bowman L; Stewart C; Horwitz E; Leung W; Benaim E; Woodard P; Tong X; Srivastava DK; Handgretinger R -
Encephalopathy in pediatric patients after allogeneic hematopoietic stem cell transplantation is associated with a poor prognosis.
Bone Marrow Transplant Volume: 33 Page(s): 1151 - 1157
06/01/2004 Authors: Woodard P; Helton K; McDaniel H; Khan RB; Thompson S; Hale G; Benaim E; Kasow K; Leung W; Horwitz E -
Rapid conversion to full chimerism after reduced intensity conditioning (RIC) and transplantation of T-cell depleted large numbers of CD34+stem and CD56+natural killer (NK) cells obtained from mobilized haploidentical donors
Volume: 10 Page(s): 56 - 56
02/01/2004 Authors: Benaim E; Hale G; Horwitz E; Leung W; Woodard P; Yusuf U; Handgretinger R -
Malignant infantile osteopetrosis and primary pulmonary hypertension: a new combination?
Pediatr Blood Cancer Volume: 42 Page(s): 190 - 194
02/01/2004 Authors: Kasow KA; Bonfim C; Asch J; Margolis DA; Jenkins J; Tamburro RF; Handgretinger R; Horwitz EM -
Effective donor lymphohematopoietic reconstitution after haploidentical CD34+-selected hematopoietic stem cell transplantation in children with refractory severe aplastic anemia.
Bone Marrow Transplant Volume: 33 Page(s): 411 - 418
02/01/2004 Authors: Woodard P; Cunningham JM; Benaim E; Chen X; Hale G; Horwitz E; Houston J; Kasow K; Leung W; Wang W -
Etiology and outcome of graft failure in pediatric hematopoietic stem cell transplant recipients.
J Pediatr Hematol Oncol Volume: 25 Page(s): 955 - 959
12/01/2003 Authors: Woodard P; Tong X; Richardson S; Srivastava DK; Horwitz EM; Benaim E; Geiger T; Hale G; Leung W; Turner V -
The unexpected discovery and toxicity of pulmonary hypertension after hematopoietic stem cell transplantation for malignant osteopetrosis: The possible existence of a genetic link or a physiologic consequence.
Volume: 102 Page(s): 426B - 426B
11/16/2003 Authors: Kasow KA; Bonfim C; Asch J; Margolis D; Jenkins J; Tamburro RF; Horwitz E -
Hemorrhagic cystitis after allogeneic bone marrow transplantation in children: clinical characteristics and outcome.
Biol Blood Marrow Transplant Volume: 9 Page(s): 698 - 705
11/01/2003 Authors: Hale GA; Rochester RJ; Heslop HE; Krance RA; Gingrich JR; Benaim E; Horwitz EM; Cunningham JM; Tong X; Srivastava DK -
Chloride channel ClCN7 mutations are responsible for severe recessive, dominant, and intermediate osteopetrosis.
J Bone Miner Res Volume: 18 Page(s): 1740 - 1747
10/01/2003 Authors: Frattini A; Pangrazio A; Susani L; Sobacchi C; Mirolo M; Abinun M; Andolina M; Flanagan A; Horwitz EM; Mihci E -
T-cell alloreactivity dominates natural killer cell alloreactivity in minimally T-cell-depleted HLA-non-identical paediatric bone marrow transplantation.
Br J Haematol Volume: 123 Page(s): 323 - 326
10/01/2003 Authors: Lowe EJ; Turner V; Handgretinger R; Horwitz EM; Benaim E; Hale GA; Woodard P; Leung W -
Allogeneic bone marrow transplantation for children with histiocytic disorders: use of TBI and omission of etoposide in the conditioning regimen.
Bone Marrow Transplant Volume: 31 Page(s): 981 - 986
06/01/2003 Authors: Hale GA; Bowman LC; Woodard JP; Cunningham JM; Benaim E; Horwitz EM; Heslop HE; Krance RA; Leung W; Shearer PD -
Stem cell plasticity: a new image of the bone marrow stem cell.
Curr Opin Pediatr Volume: 15 Page(s): 32 - 37
02/01/2003 Authors: Horwitz EM -
Clinical gene-marking of mesenchymal cells.
Cytotherapy Volume: 5 Page(s): 194 - 196
01/01/2003 Authors: Horwitz EM; Kasow KA; Hofmann TJ -
Bone marrow transplantation: it's not just about blood anymore!
Volume: 7 Suppl 3 Page(s): 56 - 58
01/01/2003 Authors: Horwitz EM -
Stem cell plasticity: the growing potential of cellular therapy.
Arch Med Res Volume: 34 Page(s): 600 - 606
01/01/2003 Authors: Horwitz EM -
The H2K enhancer/promoter directs high level, pancellular transgenic expression of the green fluorescent protein in both primitive murine hematopoietic cells and their multilineage progeny.
Volume: 100 Page(s): 611A - 611A
11/16/2002 Authors: Dominici M; Allay ER; Ney PA; Horwitz EM; Persons DA -
Retroviral integration site analysis reveals a common bone marrow progenitor for hematopoietic and osteogenic cells in a murine transplant model.
Volume: 100 Page(s): 513A - 513A
11/16/2002 Authors: Dominici M; Pritchard C; Hofmann TJ; Garlits J; Persons DA; Horwitz EM -
Bone marrow cells engraft in bone and cartilage: Regional and temporal characteristics.
Volume: 100 Page(s): 513A - 513A
11/16/2002 Authors: Dominici M; Garlits J; Hofmann TJ; Ingrassia A; Horwitz EM -
Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone.
Proc Natl Acad Sci U S A Volume: 99 Page(s): 8932 - 8937
06/25/2002 Authors: Horwitz EM; Gordon PL; Koo WKK; Marx JC; Neel MD; McNall RY; Muul L; Hofmann T -
Reversal of obstructive sleep apnea in osteopetrosis following bone marrow transplantation.
Clin Pediatr (Phila) Volume: 41 Page(s): 55 - 57
01/01/2002 Authors: Stocks R; Cannon CB; Wang WC; Horwitz EM; Thompson JW -
On the development of cell therapy for genetic disorders.
Cytotherapy Volume: 4 Page(s): 511 - 512
01/01/2002 Authors: Horwitz EM; Hofmann TJ; Garlits JE; Campioni D; Dominici M -
Nonadherent marrow stem cells give rise to blood and marrow mesenchymal stromal cells in mouse and monkey: Toward hematopoietic stem cell plasticity and the mesenchymal stem cell.
Volume: 98 Page(s): 713A - 714A
11/16/2001 Authors: Horwitz EM; Hofmann TJ; Kelly PF; Vanin EF; Donahue RE; Brown PS; Dominici M; Persons DA -
Bone marrow-derived cells contribute to tumor neovasculature and, when modified to express an angiogenesis inhibitor, can restrict tumor growth in mice.
Clin Cancer Res Volume: 7 Page(s): 2870 - 2879
09/01/2001 Authors: Davidoff AM; Ng CY; Brown P; Leary MA; Spurbeck WW; Zhou J; Horwitz E; Vanin EF; Nienhuis AW -
The mutational spectrum of human malignant autosomal recessive osteopetrosis.
Hum Mol Genet Volume: 10 Page(s): 1767 - 1773
08/15/2001 Authors: Sobacchi C; Frattini A; Orchard P; Porras O; Tezcan I; Andolina M; Babul-Hirji R; Baric I; Canham N; Chitayat D -
Allogeneic bone marrow transplantation for infants with acute leukemia or myelodysplastic syndrome.
Bone Marrow Transplant Volume: 27 Page(s): 717 - 722
04/01/2001 Authors: Leung W; Pitts N; Burnette K; Cunningham JM; Horwitz EM; Benaim E; Hale G; Woodard P; Pui CH; Bowman LC -
Effect of HLA class I or class II incompatibility in pediatric marrow transplantation from unrelated and related donors.
Hum Immunol Volume: 62 Page(s): 399 - 407
04/01/2001 Authors: Leung WH; Turner V; Richardson SL; Benaim E; Hale G; Horwitz EM; Woodard P; Bowman LC -
Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta.
Blood Volume: 97 Page(s): 1227 - 1231
03/01/2001 Authors: Horwitz EM; Prockop DJ; Gordon PL; Koo WW; Fitzpatrick LA; Neel MD; McCarville ME; Orchard PJ; Pyeritz RE; Brenner MK -
The predictive value of serum interleukins in recurrent respiratory papillomatosis: a preliminary study.
Laryngoscope Volume: 111 Page(s): 404 - 408
03/01/2001 Authors: Snowden RT; Thompson J; Horwitz E; Stocks RM -
Successful unrelated donor bone marrow transplantation for paroxysmal nocturnal hemoglobinuria.
Bone Marrow Transplant Volume: 27 Page(s): 589 - 592
03/01/2001 Authors: Woodard P; Wang W; Pitts N; Benaim E; Horwitz E; Cunningham J; Bowman L -
Improved cerebrovascular patency following therapy in patients with sickle cell disease: initial results in 4 patients who received HLA-identical hematopoietic stem cell allografts.
Ann Neurol Volume: 49 Page(s): 222 - 229
02/01/2001 Authors: Steen RG; Helton KJ; Horwitz EM; Benaim E; Thompson S; Bowman LC; Krance R; Wang WC; Cunningham JM -
Bone marrow mesenchymal cells: biological properties and clinical applications.
J Biol Regul Homeost Agents Volume: 15 Page(s): 28 - 37
01/01/2001 Authors: Dominici M; Hofmann TJ; Horwitz EM -
Allogeneic bone marrow transplantation in children failing prior autologous bone marrow transplantation.
Bone Marrow Transplant Volume: 27 Page(s): 155 - 162
01/01/2001 Authors: Hale GA; Tong X; Benaim E; Cunningham JM; Heslop HE; Horwiz EM; Leung W; Rochester RJ; Shearer PD; Srivastava DK -
Marrow mesenchymal cell transplantation for genetic disorders of bone.
Volume: 3 Page(s): 399 - 401
01/01/2001 Authors: Horwitz EM -
Outcomes of 44 pediatric MDS and JMML patients treated with allogeneic BMT: Support for early transplantation.
Volume: 96 Page(s): 415A - 415A
11/16/2000 Authors: Haight AE; Woodard P; Srivastava DK; Raimondi SC; Behm FG; Ribeiro RC; Cunningham JM; Benaim E; Horwitz EM; Hale GA -
Long term in vivo fate of human hemopoietic cells transduced by Moloney-based retroviral vectors.
Volume: 96 Page(s): 844A - 844A
11/16/2000 Authors: Rill DR; Sycamore DL; Smith SS; Horwitz EM; Krance RA; Heslop HE; Brenner MK -
Transplanted allogeneic gene-marked marrow mesenchymal cells engraft and benefit children with severe osteogenesis imperfecta.
Volume: 96 Page(s): 800A - 800A
11/16/2000 Authors: Horwitz EM; Gordon PL; Koo WK; Neel MD; Brown PS; Marx JC; Hofmann TJ -
Tumor vaccines with cytokine secreting bystander cells in murine AML.
Volume: 96 Page(s): 122A - 122A
11/16/2000 Authors: McNall RY; Borrello I; Horwitz EM -
Bone marrow stromal cells in acute promyelocytic leukemia: Comparison with other acute myelogenous leukemia subtypes.
Volume: 96 Page(s): 201B - 201B
11/16/2000 Authors: Dominici M; Campioni D; Lanza F; Moretti S; Horwitz EM; Spanedda R; Castoldi G -
Engraftment of a T-cell depleted matched unrelated donor stem cell graft using non-myeloablative conditioning.
Volume: 96 Page(s): 361B - 361B
11/16/2000 Authors: Kasow KA; Woodard P; Benaim E; Hale GA; Leung W; Bowman LC; Horwitz EM -
Successful unrelated donor BMT for paroxysmal nocturnal hemoglobinuria.
Volume: 96 Page(s): 366B - 366B
11/16/2000 Authors: Woodard P; Wang W; Pitts N; Benaim E; Horwitz E; Hale G; Leung W; Cunningham J; Bowman L -
A retrospective double-cohort study of allogeneic bone marrow transplantation for infants with acute leukemia or myelodysplastic syndrome.
Volume: 96 Page(s): 418A - 418A
11/16/2000 Authors: Leung W; Pitts N; Burnette K; Cunningham J; Horwitz E; Benaim E; Hale G; Woodard P; Pui CH; Bowman LC -
Bone marrow-derived cells contribute to tumor neovasculature and when modified to express an angiogenesis inhibitor, restrict tumor growth in mice.
Volume: 96 Page(s): 804A - 804A
11/16/2000 Authors: Davidoff AM; Leary R; Ng CYC; Spurbeck W; Brown P; Horwitz EM; Nienhuis AW; Vanin EF -
Comparison of three retroviral envelopes for high efficiency gene transfer into human marrow mesenchymal cells.
Volume: 96 Page(s): 220A - 220A
11/16/2000 Authors: Hofmann TJ; Capizzani TR; Kelly PF; Vanin EF; Horwitz EM -
Reversal of optic canal stenosis in osteopetrosis after bone marrow transplant.
Am J Ophthalmol Volume: 130 Page(s): 370 - 372
09/01/2000 Authors: Kerr NC; Wang WC; Mohadjer Y; Haik BG; Kaste SC; Horwitz EM -
Nonhematopoietic mesenchymal stem cells: what are they?
Cytotherapy Volume: 2 Page(s): 387 - 388
01/01/2000 Authors: Horwitz EM; Keating A -
Efficacy with minimal toxicity associated with the administration of donor lymphocyte infusions in pediatric bone marrow transplant recipients.
Volume: 94 Page(s): 375B - 375B
11/15/1999 Authors: Benaim E; Hale GA; Srivastava DK; Cunningham JM; Horwitz EM; Heslop HE; Brenner MK; Krance RA; Bowman LC -
Characteristics and outcome of graft failure in pediatric recipients of allogeneic stem cell transplants (SCT).
Volume: 94 Page(s): 331A - 331A
11/15/1999 Authors: Woodard P; Benaim E; Cunningham JM; Horwitz EM; Leung W; Shearer P; Hale G; Bowman C -
Nonadherent marrow cells give rise to the marrow stromal microenvironment after BMT in a murine model.
Volume: 94 Page(s): 38A - 38A
11/15/1999 Authors: Horwitz EM; Marx JC; Brown PS; Allay JA; Persons DA -
Engraftment and clinical benefit from bone marrow mesenchymal cell transplantation for children with osteogenesis imperfecta.
Volume: 94 Page(s): 609A - 609A
11/15/1999 Authors: Horwitz EM; Prockop DJ; Koo WW; Fitzpatrick LA; Gordon PL; Neel MD; Brown PS; Marx JC; Orchard P; Pyeritz RE -
High-efficiency transduction and long-term gene expression with a murine stem cell retroviral vector encoding the green fluorescent protein in human marrow stromal cells.
Hum Gene Ther Volume: 10 Page(s): 1163 - 1173
05/01/1999 Authors: Marx JC; Allay JA; Persons DA; Nooner SA; Hargrove PW; Kelly PF; Vanin EF; Horwitz EM -
Osteogenesis imperfecta calls for caution.
Nat Med Volume: 5 Page(s): 466 - 467
05/01/1999 Authors: Marini JC -
Osteogenesis imperfecta calls for caution - Reply
NATURE MEDICINE Volume: 5 Page(s): 466 - 467
05/01/1999 Authors: Horwitz EM; Prockop DJ; Fitzpatrick LA; Koo WWK; Marx JC; Brenner MK -
Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta.
Nat Med Volume: 5 Page(s): 309 - 313
03/01/1999 Authors: Horwitz EM; Prockop DJ; Fitzpatrick LA; Koo WW; Gordon PL; Neel M; Sussman M; Orchard P; Marx JC; Pyeritz RE -
Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta.
Volume: 92 Page(s): 137A - 137A
11/15/1998 Authors: Horwitz EM; Prockop DJ; Koo WW; Fitzpatrick LA; Gordon P; Neel M; Pyeritz R; Orchard P; Brenner MK -
Gene marked murine bone marrow stromal cells differentiate to periosteal cells, satellite cells of muscle, and adipocytes when infused into syngeneic recipients.
Volume: 92 Page(s): 467A - 467A
11/15/1998 Authors: Marx JC; Allay JA; Bodner SM; Horwitz EM -
Malignant infantile osteopetrosis: otolaryngological complications and management.
Arch Otolaryngol Head Neck Surg Volume: 124 Page(s): 689 - 694
06/01/1998 Authors: Stocks RM; Wang WC; Thompson JW; Stocks MC; Horwitz EM -
Bone marrow transplantation (BMT) to correct the mesenchymal defect of children with osteogenesis imperfecta.
Volume: 90 Page(s): 1014 - 1014
11/15/1997 Authors: Horwitz EM; Prockop DJ; Marini JC; Fitzpatrick LA; Gordon P; Koo W; Neel M; Orchard P; Brenner MK -
Comparison of outcome of allogeneic transplantation in children with leukemia using unrelated donors or mismatched family member donors.
Volume: 90 Page(s): 466 - 466
11/15/1997 Authors: Benaim E; Krance RA; Richardson S; Bowman LC; Srivastava DK; Cunningham JM; Horwitz EM; Brenner MK; Heslop HE -
High efficiency transduction of human marrow stromal cells with a bicistronic MSCV-based vector using the green fluorescent protein as a selectable marker.
Volume: 90 Page(s): 4588 - 4588
11/15/1997 Authors: Allay JA; Persons DA; Marx JC; Nooner SA; Horwitz EM -
Outcomes of transplantation with matched-sibling and unrelated-donor bone marrow in children with leukaemia.
Lancet Volume: 350 Page(s): 767 - 771
09/13/1997 Authors: Hongeng S; Krance RA; Bowman LC; Srivastava DK; Cunningham JM; Horwitz EM; Brenner MK; Heslop HE -
Identical outcomes of allogeneic matched sibling (MSD) and unrelated donor (MUD) transplantation in children with leukemia
Volume: 88 Page(s): 1926 - 1926
11/15/1996 Authors: Hongeng S; Krance RA; Bowman LC; Srivastava DK; Cunningham JM; Horwitz EM; Brenner MK; Heslop HE -
Treatment of severe osteogenesis imperfecta by allogeneic bone marrow transplantation.
Volume: 15 Page(s): 188 - 188
09/01/1996 Authors: Horwitz EM; Prockop DJ; Marini J; Fitzpatrick LA; Pyeritz R; Sussman M; Orchid P; Brenner MK -
A human protein containing a "cold shock" domain binds specifically to H-DNA upstream from the human gamma-globin genes.
J Biol Chem Volume: 269 Page(s): 14130 - 14139
05/13/1994 Authors: Horwitz EM; Maloney KA; Ley TJ -
INTERACTION OF A HUMAN COLD SHOCK DNA-BINDING PROTEIN WITH A SECONDARY DNA-STRUCTURE UPSTREAM FROM THE HUMAN GAMMA-GLOBIN GENES
Volume: 82 Page(s): A434 - A434
11/15/1993 Authors: HORWITZ EM; MALONEY KA; LEY TJ -
Quantitative analysis of internalization of glucagon by isolated hepatocytes.
Arch Biochem Biophys Volume: 267 Page(s): 758 - 769
12/01/1988 Authors: Horwitz EM; Gurd RS -
Guanine nucleotide regulation of the interconversion of the two-state hepatic glucagon receptor system of rat.
Arch Biochem Biophys Volume: 262 Page(s): 532 - 542
05/01/1988 Authors: Wyborski RJ; Horwitz EM; Jenkins WT; Mormol JS; Gurd RS -
Partial agonism in the glucagon receptor system is a consequence of the two-state rat hepatic receptor.
J Biol Chem Volume: 261 Page(s): 13670 - 13676
10/15/1986 Authors: Horwitz EM; Wyborski RJ; Gurd RS -
2 STAGE BINDING OF GLUCAGON TO RECEPTORS IN RAT-LIVER PLASMA-MEMBRANES
Volume: 45 Page(s): 799 - 799
03/05/1986 Authors: WYBORSKI RJ; HORWITZ EM; GURD RS -
Kinetic identification of a two-state glucagon receptor system in isolated hepatocytes. Interconversion of homogeneous receptors.
J Biol Chem Volume: 260 Page(s): 9307 - 9315
08/05/1985 Authors: Horwitz EM; Jenkins WT; Hoosein NM; Gurd RS -
QUANTITATION OF RECEPTOR MEDIATED ENDOCYTOSIS OF GLUCAGON BY FRESHLY ISOLATED RAT HEPATOCYTES
Volume: 44 Page(s): 1236 - 1236
01/01/1985 Authors: HORWITZ EM; SUTTON TA; GURD RS -
Semisynthetic derivatives of glucagon. The contribution of histidine-1 to hormone conformation and activity.
J Biol Chem Volume: 259 Page(s): 7031 - 7037
06/10/1984 Authors: Flanders KC; Horwitz EM; Gurd RS -
SEMISYNTHETIC GLN1-N-EPSILON-ACETIMIDOGLUCAGON - SIDE-CHAIN CONTROL OF RECEPTOR-BINDING AND TRANSDUCTION
Volume: 43 Page(s): 694 - 694
01/01/1984 Authors: SHETLER KA; FLANDERS KC; HORWITZ EM; GURD RS -
2 STAGE BINDING OF GLUCAGON TO A HOMOGENEOUS POPULATION OF NONCOOPERATIVE RECEPTORS IN ISOLATED RAT HEPATOCYTES
Volume: 43 Page(s): 694 - 694
01/01/1984 Authors: HORWITZ EM; JENKINS WT; HOOSEIN NM; GURD RS -
KINETIC DETERMINATION OF NONCOOPERATIVE INTERACTIONS OF GLUCAGON WITH A HOMOGENEOUS RECEPTOR POPULATION IN ISOLATED RAT HEPATOCYTES
Volume: 45 Page(s): A206 - A206
01/01/1984 Authors: HORWITZ EM; JENKINS WT; HOOSEIN NM; GURD RS -
MYOGLOBIN SEMISYNTHESIS BY FRAGMENT CONDENSATION
Volume: 40 Page(s): 1593 - 1593
01/01/1981 Authors: BROWN HK; HORWITZ EM; WANG CC; GURD FRN