Elisabeth Binder
Academic Appointment
- Full Professor, Psychiatry and Behavioral Science, Emory University School of Medicine
Education
Degrees
- PhD in Neuroscience from Emory University
- Exchange scholarship from Université Libre de Brussels
- MD from Medical School University of Vienna
Research
Publications
-
Huntingtin CAG repeat size variations below the Huntington's disease threshold: associations with depression, anxiety and basal ganglia structure.
Eur J Hum Genet Volume: 33 Page(s): 624 - 632
05/01/2025 Authors: Vater M; Rost N; Eckstein G; Sauer S; Tontsch A; Erhardt A; Lucae S; Brckl T; Klopstock T; Smann PG -
Epigenetic markers of disease risk and psychotherapy response in anxiety disorders -a longitudinal analysis of the DNA methylome.
Mol Psychiatry
04/25/2025 Authors: Domschke K; Schiele MA; Crespo Salvador ; Zillich L; Lipovsek J; Pittig A; Heinig I; Ridderbusch IC; Straube B; Richter J -
Multiomics Analysis of the Molecular Response to Glucocorticoids: Insights Into Shared Genetic Risk From Psychiatric to Medical Disorders.
Biol Psychiatry Volume: 97 Page(s): 794 - 805
04/15/2025 Authors: Knauer-Arloth J; Hryhorzhevska A; Binder EB -
Contrasting genetic predisposition and diagnosis in psychiatric disorders: A multi-omic single-nucleus analysis of the human OFC.
Sci Adv Volume: 11 Page(s): eadq2290
03/07/2025 Authors: Gerstner N; Frhlich AS; Matosin N; Gagliardi M; Cruceanu C; Kdel M; Rex-Haffner M; Tu X; Mostafavi S; Ziller MJ -
Insights from a methylome-wide association study of antidepressant exposure.
Nat Commun Volume: 16 Page(s): 1908
02/24/2025 Authors: Davyson E; Shen X; Huider F; Adams MJ; Borges K; McCartney DL; Barker LF; van Dongen J; Boomsma DI; Weihs A -
Stress Molecular Signaling in Interaction With Cognition.
Biol Psychiatry Volume: 97 Page(s): 349 - 358
02/15/2025 Authors: Lugenbhl JF; Viho EMG; Binder EB; Daskalakis NP -
Chronic exposure to glucocorticoids amplifies inhibitory neuron cell fate during human neurodevelopment in organoids.
Sci Adv Volume: 11 Page(s): eadn8631
02/14/2025 Authors: Dony L; Krontira AC; Kaspar L; Ahmad R; Demirel IS; Grochowicz M; Schfer T; Begum F; Sportelli V; Raimundo C -
Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies.
Cell Volume: 188 Page(s): 640 - 652.e9
02/06/2025 Authors: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Electronic address: andrew.mcintosh@ed.ac.uk; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium -
Genetic predisposition for negative affect predicts mental health burden during the COVID-19 pandemic.
Eur Arch Psychiatry Clin Neurosci Volume: 275 Page(s): 61 - 73
02/01/2025 Authors: Schowe AM; Godara M; Czamara D; Adli M; Singer T; Binder EB -
Identifying genetic differences between bipolar disorder and major depression through multiple genome-wide association analyses.
Br J Psychiatry Volume: 226 Page(s): 79 - 90
02/01/2025 Authors: Panagiotaropoulou G; Hellberg K-LG; Coleman JRI; Seok D; Kalman J; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; iPSYCH Study Consortium; Mitchell PB; Schofield PR -
Epigenetic signature of very low birth weight in young adult life.
Pediatr Res Volume: 97 Page(s): 229 - 238
01/01/2025 Authors: Kuula J; Czamara D; Hauta-Alus H; Lahti J; Hovi P; Miettinen ME; Ronkainen J; Eriksson JG; Andersson S; Jrvelin M-R -
Dissecting depression symptoms: Multi-omics clustering uncovers immune-related subgroups and cell-type specific dysregulation.
Brain Behav Immun Volume: 123 Page(s): 353 - 369
01/01/2025 Authors: Hagenberg J; BeCOME study group; OPTIMA study group; Brckl TM; Erhart M; Kopf-Beck J; Kdel M; Rehawi G; Rh-Karamihalev S; Sauer S -
Publisher Correction: An integrated transcriptomic cell atlas of human neural organoids.
Nature Volume: 637 Page(s): E21
01/01/2025 Authors: He Z; Dony L; Fleck JS; Szaata A; Li KX; Slikovi I; Lin H-C; Santel M; Atamian A; Quadrato G -
Placental epigenetic signatures of maternal distress in glucocorticoid-related genes and newborn outcomes: A study of Spanish primiparous women.
Eur Neuropsychopharmacol Volume: 90 Page(s): 36 - 47
01/01/2025 Authors: Castro-Quintas A; Palma-Gudiel H; Eixarch E; San Martn Gonzlez N; Rh S; Sauer S; Rex-Haffner M; Monteserin-Garcia JL; de la Fuente-Toms L; Crispi F -
Differential Dynamics and Roles of FKBP51 Isoforms and Their Implications for Targeted Therapies.
Int J Mol Sci Volume: 25
11/16/2024 Authors: Martinelli S; Hafner K; Koedel M; Knauer-Arloth J; Gassen NC; Binder EB -
An integrated transcriptomic cell atlas of human neural organoids.
Nature Volume: 635 Page(s): 690 - 698
11/01/2024 Authors: He Z; Dony L; Fleck JS; Szaata A; Li KX; Slikovi I; Lin H-C; Santel M; Atamian A; Quadrato G -
Prenatal exposures and cell type proportions are main drivers of FKBP5 DNA methylation in maltreated and non-maltreated children.
Neurobiol Stress Volume: 33 Page(s): 100687
11/01/2024 Authors: Karlbauer VN; Martins J; Rex-Haffner M; Sauer S; Roeh S; Dittrich K; Doerr P; Klawitter H; Entringer S; Buss C -
Altered Gut Microbiota Patterns in Young Children with Recent Maltreatment Exposure.
Biomolecules Volume: 14
10/16/2024 Authors: Karaboycheva G; Conrad ML; Drr P; Dittrich K; Murray E; Skonieczna-ydecka K; Kaczmarczyk M; oniewski I; Klawitter H; Buss C -
Quantitative trait locus mapping in placenta: A comparative study of chorionic villus and birth placenta.
HGG Adv Volume: 5 Page(s): 100326
10/10/2024 Authors: Dieckmann L; Lahti-Pulkkinen M; Cruceanu C; Rikknen K; Binder EB; Czamara D -
Single-nucleus transcriptomic profiling of human orbitofrontal cortex reveals convergent effects of aging and psychiatric disease.
Nat Neurosci Volume: 27 Page(s): 2021 - 2032
10/01/2024 Authors: Frhlich AS; Gerstner N; Gagliardi M; Kdel M; Yusupov N; Matosin N; Czamara D; Sauer S; Roeh S; Murek V -
Discrepancies in readouts between Infinium MethylationEPIC v2.0 and v1.0 reflected in DNA methylation-based tools: implications and considerations for human population epigenetic studies.
bioRxiv
09/28/2024 Authors: Zhuang BC; Jude MS; Konwar C; Yusupov N; Ryan CP; Engelbrecht H-R; Whitehead J; Halberstam AA; MacIsaac JL; Dever K -
[Genetic diagnostics of mental health disorders in adulthood].
Nervenarzt
09/24/2024 Authors: Kilarski LL; Claus I; Binder EB; Degenhardt F; Domschke K; Forstner AJ; Grabe HJ; Heilbronner U; Mller D; Nthen MM -
Serial Diurnal Salivary Cortisol Profiles in 667 Pregnant Women-Association With Cardiometabolic Complications.
J Clin Endocrinol Metab Volume: 109 Page(s): 2491 - 2503
09/16/2024 Authors: Schowe AM; Czamara D; Lahti-Pulkkinen M; Girchenko P; Castro-Quintas ; Faanas L; Binder EB; Rikknen K -
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling.
medRxiv
07/05/2024 Authors: Strom NI; Verhulst B; Bacanu S-A; Cheesman R; Purves KL; Gedik H; Mitchell BL; Kwong AS; Faucon AB; Singh K -
The effects of pregnancy, its progression, and its cessation on human (maternal) biological aging.
Cell Metab Volume: 36 Page(s): 877 - 878
05/07/2024 Authors: Pham H; Thompson-Felix T; Czamara D; Rasmussen JM; Lombroso A; Entringer S; Binder EB; Wadhwa PD; Buss C; O'Donnell KJ -
Antidepressant Exposure and DNA Methylation: Insights from a Methylome-Wide Association Study.
medRxiv
05/03/2024 Authors: Davyson E; Shen X; Huider F; Adams M; Borges K; McCartney D; Barker L; Van Dongen J; Boomsma D; Weihs A -
DNA methylation patterns of FKBP5 regulatory regions in brain and blood of humanized mice and humans.
Mol Psychiatry Volume: 29 Page(s): 1510 - 1520
05/01/2024 Authors: Yusupov N; Roeh S; Sotillos Elliott L; Chang S; Loganathan S; Urbina-Trevio L; Frhlich AS; Sauer S; Kdel M; Matosin N -
Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression.
Neuron Volume: 112 Page(s): 1426 - 1443.e11
05/01/2024 Authors: Krontira AC; Cruceanu C; Dony L; Kyrousi C; Link M-H; Rek N; Phlchen D; Raimundo C; Penner-Goeke S; Schowe A -
Sex differences in DNA methylation across gestation: a large scale, cross-cohort, multi-tissue analysis.
Cell Mol Life Sci Volume: 81 Page(s): 177
04/10/2024 Authors: Czamara D; Dieckmann L; Lahti-Pulkkinen M; Cruceanu C; Henrich W; Plagemann A; Rikknen K; Braun T; Binder EB; Lahti J -
Free-viewing gaze patterns reveal a mood-congruency bias in MDD during an affective fMRI/eye-tracking task.
Eur Arch Psychiatry Clin Neurosci Volume: 274 Page(s): 559 - 571
04/01/2024 Authors: Sun R; Fietz J; Erhart M; Poehlchen D; Henco L; Brckl TM; BeCOME study team; Czisch M; Saemann PG; Spoormaker VI -
Multiomics and blood-based biomarkers of electroconvulsive therapy in severe and treatment-resistant depression: study protocol of the DetECT study.
Eur Arch Psychiatry Clin Neurosci Volume: 274 Page(s): 673 - 684
04/01/2024 Authors: von Mcke-Heim I-A; Pape JC; Grandi NC; Erhardt A; Deussing JM; Binder EB -
Linking environmental factors and gene regulation.
Elife Volume: 13
03/18/2024 Authors: Penner-Goeke S; Binder EB -
Cohort profile: BioMD-Y (biopsychosocial factors of major depression in youth) - a biobank study on the molecular genetics and environmental factors of depression in children and adolescents in Munich.
BMJ Open Volume: 14 Page(s): e074925
03/13/2024 Authors: Scherff AD; Feldmann L; Piechaczek C; Pehl V; Wagenbchler P; Wermuth I; Ghotbi N; Allgaier A-K; Freisleder FJ; Beins EC -
Methylation Patterns of the FKBP5 Gene in Association with Childhood Maltreatment and Depressive Disorders.
Int J Mol Sci Volume: 25
01/25/2024 Authors: Gromann NL; Weihs A; Khn L; Sauer S; Rh S; Wiechmann T; Rex-Haffner M; Vlzke H; Vlker U; Binder EB -
Assessing hypo-arousal during reward anticipation with pupillometry in patients with major depressive disorder: replication and correlations with anhedonia.
Sci Rep Volume: 14 Page(s): 344
01/03/2024 Authors: Brendler A; Schneider M; Elbau IG; Sun R; Nantawisarakul T; Phlchen D; Brckl T; BeCOME Working Group; Czisch M; Smann PG -
A Glucocorticoid-Sensitive Hippocampal Gene Network Moderates the Impact of Early-Life Adversity on Mental Health Outcomes.
Biol Psychiatry Volume: 95 Page(s): 48 - 61
01/01/2024 Authors: Arcego DM; Buschdorf J-P; O'Toole N; Wang Z; Barth B; Pokhvisneva I; Rayan NA; Patel S; de Mendona Filho EJ; Lee P -
High-throughput screening of glucocorticoid-induced enhancer activity reveals mechanisms of stress-related psychiatric disorders.
Proc Natl Acad Sci U S A Volume: 120 Page(s): e2305773120
12/05/2023 Authors: Penner-Goeke S; Bothe M; Rek N; Kreitmaier P; Phlchen D; Khnel A; Glaser LV; Kaya E; Krontira AC; Rh S -
Maternal exposure to childhood maltreatment and mental and behavioral disorders in children.
Eur Child Adolesc Psychiatry Volume: 32 Page(s): 2463 - 2475
12/01/2023 Authors: Airikka A; Lahti-Pulkkinen M; Tuovinen S; Heinonen K; Lahti J; Girchenko P; Lhdepuro A; Pyhl R; Czamara D; Villa P -
Epigenome-wide meta-analysis of prenatal maternal stressful life events and newborn DNA methylation.
Mol Psychiatry Volume: 28 Page(s): 5090 - 5100
12/01/2023 Authors: Kotsakis Ruehlmann A; Sammallahti S; Corts Hidalgo AP; Bakulski KM; Binder EB; Campbell ML; Caramaschi D; Cecil CAM; Colicino E; Cruceanu C -
Epigenetic age acceleration as a biomarker for impaired cognitive abilities in adulthood following early life adversity and psychiatric disorders.
Neurobiol Stress Volume: 27 Page(s): 100577
11/01/2023 Authors: Felt JM; Yusupov N; Harrington KD; Fietz J; Zhang ZZ; Sliwinski MJ; Ram N; O'Donnell KJ; BeCOME Working Group; Meaney MJ -
Greater maltreatment severity is associated with smaller brain volume with implication for intellectual ability in young children.
Neurobiol Stress Volume: 27 Page(s): 100576
11/01/2023 Authors: Joseph J; Buss C; Knop A; de Punder K; Winter SM; Spors B; Binder E; Haynes J-D; Heim C -
Epigenetic aging and PTSD outcomes in the immediate aftermath of trauma.
Psychol Med Volume: 53 Page(s): 7170 - 7179
11/01/2023 Authors: Zannas AS; Linnstaedt SD; An X; Stevens JS; Harnett NG; Roeckner AR; Oliver KI; Rubinow DR; Binder EB; Koenen KC -
Stress-induced brain responses are associated with BMI in women.
Commun Biol Volume: 6 Page(s): 1031
10/11/2023 Authors: Khnel A; Hagenberg J; Knauer-Arloth J; Kdel M; Czisch M; Smann PG; BeCOME working group; Binder EB; Kroemer NB -
New Insights Into Suicidal Behavior From Large Multi-Ancestry Genetic Meta-Analysis.
Am J Psychiatry Volume: 180 Page(s): 705 - 707
10/01/2023 Authors: Binder EB -
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.
Am J Psychiatry Volume: 180 Page(s): 723 - 738
10/01/2023 Authors: Docherty AR; Mullins N; Ashley-Koch AE; Qin X; Coleman JRI; Shabalin A; Kang J; Murnyak B; Wendt F; Adams M -
Extensive evaluation of DNA methylation of functional elements in the murine Fkbp5 locus using high-accuracy DNA methylation measurement via targeted bisulfite sequencing.
Eur J Neurosci Volume: 58 Page(s): 2662 - 2676
08/01/2023 Authors: Yusupov N; van Doeselaar L; Rh S; Wiechmann T; Kdel M; Sauer S; Rex-Haffner M; Schmidt MV; Binder EB -
Transdiagnostic evaluation of epigenetic age acceleration and burden of psychiatric disorders.
Neuropsychopharmacology Volume: 48 Page(s): 1409 - 1417
08/01/2023 Authors: Yusupov N; Dieckmann L; Erhart M; Sauer S; Rex-Haffner M; Kopf-Beck J; Brckl TM; Czamara D; Binder EB -
Polygenic risk prediction: why and when out-of-sample prediction R2 can exceed SNP-based heritability.
Am J Hum Genet Volume: 110 Page(s): 1207 - 1215
07/06/2023 Authors: Wang X; Walker A; Revez JA; Ni G; Adams MJ; McIntosh AM; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Visscher PM; Wray NR -
Multimodal predictions of treatment outcome in major depression: A comparison of data-driven predictors with importance ratings by clinicians.
J Affect Disord Volume: 327 Page(s): 330 - 339
04/14/2023 Authors: Rost N; Dwyer DB; Gaffron S; Rechberger S; Maier D; Binder EB; Brckl TM -
Startle Latency as a Potential Marker for Amygdala-Mediated Hyperarousal.
Biol Psychiatry Cogn Neurosci Neuroimaging Volume: 8 Page(s): 406 - 416
04/01/2023 Authors: Phlchen D; Fietz J; BeCOME Working Group; Czisch M; Smann PG; Spoormaker VI -
Guilt by Association: Inflammation and Shared Genetic Risk Between Stress-Related and Immune Disorders.
Am J Psychiatry Volume: 180 Page(s): 259 - 261
04/01/2023 Authors: Miller AH; Binder EB -
Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex.
Acta Neuropathol Volume: 145 Page(s): 439 - 459
04/01/2023 Authors: Matosin N; Arloth J; Czamara D; Edmond KZ; Maitra M; Frhlich AS; Martinelli S; Kaul D; Bartlett R; Curry AR -
Predicting treatment outcome in depression: an introduction into current concepts and challenges.
Eur Arch Psychiatry Clin Neurosci Volume: 273 Page(s): 113 - 127
02/01/2023 Authors: Rost N; Binder EB; Brckl TM -
2022 Articles of Import and Impact.
Am J Psychiatry Volume: 180 Page(s): 20 - 22
01/01/2023 -
FKBP5 intron 7 methylation is associated with higher anxiety proneness and smaller right thalamus volume in adolescents.
Brain Struct Funct Volume: 227 Page(s): 2809 - 2820
11/01/2022 Authors: Womersley JS; Roeh S; Martin L; Ahmed-Leitao F; Sauer S; Rex-Haffner M; Hemmings SMJ; Binder EB; Seedat S -
Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing.
Int J Mol Sci Volume: 23
09/28/2022 Authors: Czamara D; Cruceanu C; Lahti-Pulkkinen M; Dieckmann L; Kdel M; Sauer S; Rex-Haffner M; Sammallahti S; Kajantie E; Laivuori H -
Immediate impact of child maltreatment on mental, developmental, and physical health trajectories.
J Child Psychol Psychiatry Volume: 63 Page(s): 1027 - 1045
09/01/2022 Authors: Winter SM; Dittrich K; Drr P; Overfeld J; Moebus I; Murray E; Karaboycheva G; Zimmermann C; Knop A; Voelkle M -
Effects of Pharmacokinetic Gene Variation on Therapeutic Drug Levels and Antidepressant Treatment Response.
Pharmacopsychiatry Volume: 55 Page(s): 246 - 254
09/01/2022 Authors: Scherf-Clavel M; Weber H; Wurst C; Stonawski S; Hommers L; Unterecker S; Wolf C; Domschke K; Rost N; Brckl T -
The American Journal of Psychiatry's Efforts Toward Eliminating Racism, Social Injustice, Health Care Inequities, and Publication Biases.
Am J Psychiatry Volume: 179 Page(s): 604 - 605
09/01/2022 Authors: Kalin NH; Binder EB; Brady KT; Lewis DA; McDonald WM; Pine DS; Rodriguez CI; Roy MD -
Creating sparser prediction models of treatment outcome in depression: a proof-of-concept study using simultaneous feature selection and hyperparameter tuning.
BMC Med Inform Decis Mak Volume: 22 Page(s): 181
07/14/2022 Authors: Rost N; Brckl TM; Koutsouleris N; Binder EB; Mller-Myhsok B -
Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study.
Am J Psychiatry Volume: 179 Page(s): 375 - 387
05/01/2022 Authors: Cruceanu C; Dony L; Krontira AC; Fischer DS; Roeh S; Di Giaimo R; Kyrousi C; Kaspar L; Arloth J; Czamara D -
Tricyclic antidepressants target FKBP51 SUMOylation to restore glucocorticoid receptor activity.
Mol Psychiatry Volume: 27 Page(s): 2533 - 2545
05/01/2022 Authors: Budziski ML; Sokn C; Gobbini R; Ugo B; Antunica-Noguerol M; Senin S; Bajaj T; Gassen NC; Rein T; Schmidt MV -
Effects of stressful life-events on DNA methylation in panic disorder and major depressive disorder.
Clin Epigenetics Volume: 14 Page(s): 55
04/27/2022 Authors: Czamara D; Neufang A; Dieterle R; Iurato S; Arloth J; Martins J; Ising M; Binder EE; Erhardt A -
Identifying the Common Genetic Basis of Antidepressant Response.
Biol Psychiatry Glob Open Sci Volume: 2 Page(s): 115 - 126
04/01/2022 Authors: Pain O; Hodgson K; Trubetskoy V; Ripke S; Marshe VS; Adams MJ; Byrne EM; Campos AI; Carrillo-Roa T; Cattaneo A -
Early adversity as the prototype geneenvironment interaction in mental disorders?
Pharmacol Biochem Behav Volume: 215 Page(s): 173371
04/01/2022 Authors: Martins J; Yusupov N; Binder EB; Brckl TM; Czamara D -
Maternal Glycemic Dysregulation During Pregnancy and Neonatal Blood DNA Methylation: Meta-analyses of Epigenome-Wide Association Studies.
Diabetes Care Volume: 45 Page(s): 614 - 623
03/01/2022 Authors: Tobi EW; Juvinao-Quintero DL; Ronkainen J; Ott R; Alfano R; Canouil M; Geurtsen ML; Khamis A; Kpers LK; Lim IY -
Reliability of a novel approach for reference-based cell type estimation in human placental DNA methylation studies.
Cell Mol Life Sci Volume: 79 Page(s): 115
02/03/2022 Authors: Dieckmann L; Cruceanu C; Lahti-Pulkkinen M; Lahti J; Kvist T; Laivuori H; Sammallahti S; Villa PM; Suomalainen-Knig S; Rancourt RC -
The Manchester Triage System in a Pediatric Emergency Department of an Austrian University Hospital: A Retrospective Analysis of Urgency Levels.
Pediatr Emerg Care Volume: 38 Page(s): e639 - e643
02/01/2022 Authors: Beck N; Michel M; Binder E; Kapelari K; Maurer M; Lamina C; Mller T; Karall D; Scholl-Brgi S -
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors.
Biol Psychiatry Volume: 91 Page(s): 313 - 327
02/01/2022 Authors: Mullins N; Kang J; Campos AI; Coleman JRI; Edwards AC; Galfalvy H; Levey DF; Lori A; Shabalin A; Starnawska A -
Cohort profile: InTraUterine sampling in early pregnancy (ITU), a prospective pregnancy cohort study in Finland: study design and baseline characteristics.
BMJ Open Volume: 12 Page(s): e049231
01/31/2022 Authors: Kvist T; Sammallahti S; Lahti-Pulkkinen M; Cruceanu C; Czamara D; Dieckmann L; Tontsch A; Rh S; Rex-Haffner M; Wolford E -
The COVID-19 pandemic reduced paediatric emergency department visits but did not significantly increase urgent cases.
Acta Paediatr Volume: 111 Page(s): 130 - 132
01/01/2022 Authors: Beck N; Michel M; Klingkowski U; Binder E; Kapelari K; Maurer M; Lamina C; Mller T; Karall D; Scholl-Brgi S -
The influence of FAAH genetic variation on physiological, cognitive, and neural signatures of fear acquisition and extinction learning in women with PTSD.
Neuroimage Clin Volume: 33 Page(s): 102922
01/01/2022 Authors: Crombie KM; Privratsky AA; Schomaker CM; Heilicher M; Ross MC; Sartin-Tarm A; Sellnow K; Binder EB; Andrew James G; Cisler JM -
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.
Biol Psychiatry Volume: 91 Page(s): 102 - 117
01/01/2022 Authors: Blokland GAM; Grove J; Chen C-Y; Cotsapas C; Tobet S; Handa R; Schizophrenia Working Group of the Psychiatric Genomics Consortium; St Clair D; Lencz T; Mowry BJ -
Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation.
Mutat Res Rev Mutat Res Volume: 789 Page(s): 108415
01/01/2022 Authors: Solomon O; Huen K; Yousefi P; Kpers LK; Gonzlez JR; Suderman M; Reese SE; Page CM; Gruzieva O; Rzehak P -
Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium.
Epigenetics Volume: 17 Page(s): 19 - 31
01/01/2022 Authors: Ronkainen J; Heiskala A; Vehmeijer FOL; Lowry E; Caramaschi D; Estrada Gutierrez G; Heiss JA; Hummel N; Keikkala E; Kvist T -
Short-term oestrogen as a strategy to prevent postpartum depression in high-risk women: protocol for the double-blind, randomised, placebo-controlled MAMA clinical trial.
BMJ Open Volume: 11 Page(s): e052922
12/30/2021 Authors: Hgh S; Hegaard HK; Renault KM; Cvetanovska E; Kjrbye-Thygesen A; Juul A; Borgsted C; Bjertrup AJ; Miskowiak KW; Vver MS -
Sex differences in the genetic regulation of the blood transcriptome response to glucocorticoid receptor activation.
Transl Psychiatry Volume: 11 Page(s): 632
12/13/2021 Authors: Moore SR; Halldorsdottir T; Martins J; Lucae S; Mller-Myhsok B; Mller NS; Piechaczek C; Feldmann L; Freisleder FJ; Greimel E -
Factor H-related protein 1 (FHR-1) is associated with atherosclerotic cardiovascular disease.
Sci Rep Volume: 11 Page(s): 22511
11/18/2021 Authors: Irmscher S; Zipfel SLH; Halder LD; Ivanov L; Gonzalez-Delgado A; Waldeyer C; Seiffert M; Brunner FJ; von der Heide M; Lschmann I -
scPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies.
Nat Commun Volume: 12 Page(s): 6625
11/16/2021 Authors: Schmid KT; Hllbacher B; Cruceanu C; Bttcher A; Lickert H; Binder EB; Theis FJ; Heinig M -
Extracellular LGALS3BP regulates neural progenitor position and relates to human cortical complexity.
Nat Commun Volume: 12 Page(s): 6298
11/02/2021 Authors: Kyrousi C; O'Neill AC; Brazovskaja A; He Z; Kielkowski P; Coquand L; Di Giaimo R; D' Andrea P; Belka A; Forero Echeverry A -
The pediatric buccal epigenetic clock identifies significant ageing acceleration in children with internalizing disorder and maltreatment exposure.
Neurobiol Stress Volume: 15 Page(s): 100394
11/01/2021 Authors: Dammering F; Martins J; Dittrich K; Czamara D; Rex-Haffner M; Overfeld J; de Punder K; Buss C; Entringer S; Winter SM -
Childhood adversity correlates with stable changes in DNA methylation trajectories in children and converges with epigenetic signatures of prenatal stress.
Neurobiol Stress Volume: 15 Page(s): 100336
11/01/2021 Authors: Martins J; Czamara D; Sauer S; Rex-Haffner M; Dittrich K; Drr P; de Punder K; Overfeld J; Knop A; Dammering F -
A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts.
Biol Psychiatry Volume: 90 Page(s): 611 - 620
11/01/2021 Authors: Ni G; Zeng J; Revez JA; Wang Y; Zheng Z; Ge T; Restuadi R; Kiewa J; Nyholt DR; Coleman JRI -
Indoxyl sulfate, a gut microbiome-derived uremic toxin, is associated with psychic anxiety and its functional magnetic resonance imaging-based neurologic signature.
Sci Rep Volume: 11 Page(s): 21011
10/25/2021 Authors: Brydges CR; Fiehn O; Mayberg HS; Schreiber H; Dehkordi SM; Bhattacharyya S; Cha J; Choi KS; Craighead WE; Krishnan RR -
Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank.
Mol Psychiatry Volume: 26 Page(s): 5465
09/01/2021 Authors: Coleman JRI; Peyrot WJ; Purves KL; Davis KAS; Rayner C; Choi SW; Hbel C; Gaspar HA; Kan C; Van der Auwera S -
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation.
Nat Genet Volume: 53 Page(s): 1311 - 1321
09/01/2021 Authors: Min JL; Hemani G; Hannon E; Dekkers KF; Castillo-Fernandez J; Luijk R; Carnero-Montoro E; Lawson DJ; Burrows K; Suderman M -
Betamethasone administration during pregnancy is associated with placental epigenetic changes with implications for inflammation.
Clin Epigenetics Volume: 13 Page(s): 165
08/26/2021 Authors: Czamara D; Dieckmann L; Rh S; Kraemer S; Rancourt RC; Sammallahti S; Kajantie E; Laivuori H; Eriksson JG; Rikknen K -
Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group.
Mol Psychiatry Volume: 26 Page(s): 3884 - 3895
08/01/2021 Authors: Jia T; Chu C; Liu Y; van Dongen J; Papastergios E; Armstrong NJ; Bastin ME; Carrillo-Roa T; den Braber A; Harris M -
Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression.
Mol Psychiatry Volume: 26 Page(s): 4179 - 4190
08/01/2021 Authors: Forstner AJ; Awasthi S; Wolf C; Maron E; Erhardt A; Czamara D; Eriksson E; Lavebratt C; Allgulander C; Friedrich N -
Correction: The AURORA Study: a longitudinal, multimodal library of brain biology and function after traumatic stress exposure.
Mol Psychiatry Volume: 26 Page(s): 3658
07/01/2021 Authors: McLean SA; Ressler K; Koenen KC; Neylan T; Germine L; Jovanovic T; Clifford GD; Zeng D; An X; Linnstaedt S -
Interaction of FKBP5 variant rs3800373 and city living alters the neural stress response in the anterior cingulate cortex.
Stress Volume: 24 Page(s): 421 - 429
07/01/2021 Authors: Richter A; Al-Bayati M; Paraskevopoulou F; Krmer B; Pruessner JC; Binder EB; Gruber O -
Polygenic risk for immuno-metabolic markers and specific depressive symptoms: A multi-sample network analysis study.
Brain Behav Immun Volume: 95 Page(s): 256 - 268
07/01/2021 Authors: Kappelmann N; Czamara D; Rost N; Moser S; Schmoll V; Trastulla L; Stochl J; Lucae S; CHARGE inflammation working group; Binder EB -
Toll-like receptor 4 methylation grade is linked to depressive symptom severity.
Transl Psychiatry Volume: 11 Page(s): 371
06/24/2021 Authors: Rasmusson AJ; Gallwitz M; Soltanabadi B; Ciuculete DM; Mengel-From J; Christensen K; Nygaard M; Soerensen M; Bostrm AE; Fredriksson R -
ERICH3: vesicular association and antidepressant treatment response.
Mol Psychiatry Volume: 26 Page(s): 2415 - 2428
06/01/2021 Authors: Liu D; Zhuang Y; Zhang L; Gao H; Neavin D; Carrillo-Roa T; Wang Y; Yu J; Qin S; Kim DC -
Association of polygenic score for major depression with response to lithium in patients with bipolar disorder.
Mol Psychiatry Volume: 26 Page(s): 2457 - 2470
06/01/2021 Authors: Amare AT; Schubert KO; Hou L; Clark SR; Papiol S; Cearns M; Heilbronner U; Degenhardt F; Tekola-Ayele F; Hsu Y-H -
DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan.
Mol Psychiatry Volume: 26 Page(s): 2148 - 2162
06/01/2021 Authors: van Dongen J; Hagenbeek FA; Suderman M; Roetman PJ; Sugden K; Chiocchetti AG; Ismail K; Mulder RH; Hafferty JD; Adams MJ -
Prediction of short-term antidepressant response using probabilistic graphical models with replication across multiple drugs and treatment settings.
Neuropsychopharmacology Volume: 46 Page(s): 1272 - 1282
06/01/2021 Authors: Athreya AP; Brckl T; Binder EB; John Rush A; Biernacka J; Frye MA; Neavin D; Skime M; Monrad D; Iyer RK -
Characteristics of epigenetic aging across gestational and perinatal tissues.
Clin Epigenetics Volume: 13 Page(s): 97
04/29/2021 Authors: Dieckmann L; Lahti-Pulkkinen M; Kvist T; Lahti J; DeWitt PE; Cruceanu C; Laivuori H; Sammallahti S; Villa PM; Suomalainen-Knig S -
Comorbidity of inflammatory bowel disease in children and adolescents with type 1 diabetes.
Acta Paediatr Volume: 110 Page(s): 1353 - 1358
04/01/2021 Authors: Jasser-Nitsche H; Bechtold-Dalla Pozza S; Binder E; Bollow E; Heidtmann B; Lee-Barkley YH; Raile K; de Sousa G; Schramm U; Holl RW -
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.
Mol Psychiatry Volume: 26 Page(s): 1286 - 1298
04/01/2021 Authors: Andlauer TFM; Guzman-Parra J; Streit F; Strohmaier J; Gonzlez MJ; Gil Flores S; Cabaleiro Fabeiro FJ; Del Ro Noriega F; Perez FP; Haro Gonzlez J -
Genome-wide gene expression changes in postpartum depression point towards an altered immune landscape.
Transl Psychiatry Volume: 11 Page(s): 155
03/04/2021 Authors: Mehta D; Grewen K; Pearson B; Wani S; Wallace L; Henders AK; Binder EB; Frokjaer VG; Meltzer-Brody S; Wray NR -
Alterations in acylcarnitines, amines, and lipids inform about the mechanism of action of citalopram/escitalopram in major depression.
Transl Psychiatry Volume: 11 Page(s): 153
03/02/2021 Authors: MahmoudianDehkordi S; Ahmed AT; Bhattacharyya S; Han X; Baillie RA; Arnold M; Skime MK; John-Williams LS; Moseley MA; Thompson JW -
Intergenerational trauma is associated with expression alterations in glucocorticoid- and immune-related genes.
Neuropsychopharmacology Volume: 46 Page(s): 763 - 773
03/01/2021 Authors: Daskalakis NP; Xu C; Bader HN; Chatzinakos C; Weber P; Makotkine I; Lehrner A; Bierer LM; Binder EB; Yehuda R -
Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive Symptoms: A Genetic Correlation and 2-Sample Mendelian Randomization Study.
JAMA Psychiatry Volume: 78 Page(s): 161 - 170
02/01/2021 Authors: Kappelmann N; Arloth J; Georgakis MK; Czamara D; Rost N; Ligthart S; Khandaker GM; Binder EB -
Combined effects of genotype and childhood adversity shape variability of DNA methylation across age.
Transl Psychiatry Volume: 11 Page(s): 88
02/01/2021 Authors: Czamara D; Tissink E; Tuhkanen J; Martins J; Awaloff Y; Drake AJ; Khulan B; Palotie A; Winter SM; Nemeroff CB -
Genotype-Phenotype Predictions in Autism: Are We There Yet?
Am J Psychiatry Volume: 178 Page(s): 11 - 12
01/01/2021 Authors: Binder EB -
2020 Articles of Import and Impact.
Am J Psychiatry Volume: 178 Page(s): 13 - 16
01/01/2021 Authors: Kalin NH; Binder E; Brady KT; Lewis DA; Pine DS; Rodriguez C; Trivedi MH; Edwards ML -
Investigating differential effects of socio-emotional and mindfulness-based online interventions on mental health, resilience and social capacities during the COVID-19 pandemic: The study protocol.
PLoS One Volume: 16 Page(s): e0256323
01/01/2021 Authors: Godara M; Silveira S; Matthus H; Heim C; Voelkle M; Hecht M; Binder EB; Singer T -
Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation.
Sci Adv Volume: 7
01/01/2021 Authors: Lopez JP; Brivio E; Santambrogio A; De Donno C; Kos A; Peters M; Rost N; Czamara D; Brckl TM; Roeh S -
Immediate and longitudinal effects of maltreatment on systemic inflammation in young children.
Dev Psychopathol Volume: 32 Page(s): 1725 - 1731
12/01/2020 Authors: Entringer S; de Punder K; Overfeld J; Karaboycheva G; Dittrich K; Buss C; Winter SM; Binder EB; Heim C -
DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies.
Genome Med Volume: 12 Page(s): 105
11/25/2020 Authors: Vehmeijer FOL; Kpers LK; Sharp GC; Salas LA; Lent S; Jima DD; Tindula G; Reese S; Qi C; Gruzieva O -
Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis.
Transl Psychiatry Volume: 10 Page(s): 398
11/12/2020 Authors: Neumann A; Walton E; Alemany S; Cecil C; Gonzlez JR; Jima DD; Lahti J; Tuominen ST; Barker ED; Binder E -
Severe childhood and adulthood stress associates with neocortical layer-specific reductions of mature spines in psychiatric disorders.
Neurobiol Stress Volume: 13 Page(s): 100270
11/01/2020 Authors: Kaul D; Smith CC; Stevens J; Frhlich AS; Binder EB; Mechawar N; Schwab SG; Matosin N -
A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders.
Neurobiol Stress Volume: 13 Page(s): 100275
11/01/2020 Authors: Suarez A; Lahti J; Lahti-Pulkkinen M; Girchenko P; Czamara D; Arloth J; Malmberg AL; Hmlinen E; Kajantie E; Laivuori H -
Understanding the mechanisms of treatment response in depression, focus on electro-convulsive therapy.
Eur Arch Psychiatry Clin Neurosci Volume: 270 Page(s): 789 - 791
10/01/2020 Authors: Binder EB -
Psychosocial stress reactivity habituates following acute physiological stress.
Hum Brain Mapp Volume: 41 Page(s): 4010 - 4023
10/01/2020 Authors: Khnel A; Kroemer NB; Elbau IG; Czisch M; Smann PG; Walter M; BeCome working group; Binder EB -
Biological embedding of experience: A primer on epigenetics.
Proc Natl Acad Sci U S A Volume: 117 Page(s): 23261 - 23269
09/22/2020 Authors: Aristizabal MJ; Anreiter I; Halldorsdottir T; Odgers CL; McDade TW; Goldenberg A; Mostafavi S; Kobor MS; Binder EB; Sokolowski MB -
The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells.
Proc Natl Acad Sci U S A Volume: 117 Page(s): 23329 - 23335
09/22/2020 Authors: McEwen LM; O'Donnell KJ; McGill MG; Edgar RD; Jones MJ; MacIsaac JL; Lin DTS; Ramadori K; Morin A; Gladish N -
Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation.
Proc Natl Acad Sci U S A Volume: 117 Page(s): 23280 - 23285
09/22/2020 Authors: Provenal N; Arloth J; Cattaneo A; Anacker C; Cattane N; Wiechmann T; Rh S; Kdel M; Klengel T; Czamara D -
The role of the genome in experience-dependent plasticity: Extending the analogy of the genomic action potential.
Proc Natl Acad Sci U S A Volume: 117 Page(s): 23252 - 23260
09/22/2020 Authors: Clayton DF; Anreiter I; Aristizabal M; Frankland PW; Binder EB; Citri A -
The American Journal of Psychiatry's Commitment to Combat Racism, Social Injustice, and Health Care Inequities.
Am J Psychiatry Volume: 177 Page(s): 791
09/01/2020 Authors: Kalin NH; Binder E; Brady KT; Lewis DA; Pine DS; Rodriguez C; Trivedi MH -
Polygenic prediction of the risk of perinatal depressive symptoms.
Depress Anxiety Volume: 37 Page(s): 862 - 875
09/01/2020 Authors: Rantalainen V; Binder EB; Lahti-Pulkkinen M; Czamara D; Laivuori H; Villa PM; Girchenko P; Kvist T; Hmlinen E; Kajantie E -
Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression.
Am J Med Genet B Neuropsychiatr Genet Volume: 183 Page(s): 309 - 330
09/01/2020 Authors: Hagenaars SP; Coleman JRI; Choi SW; Gaspar H; Adams MJ; Howard DM; Hodgson K; Traylor M; Air TM; Andlauer TFM -
Intergenerational Effects of Maternal Holocaust Exposure on FKBP5 Methylation.
Am J Psychiatry Volume: 177 Page(s): 744 - 753
08/01/2020 Authors: Bierer LM; Bader HN; Daskalakis NP; Lehrner A; Provenal N; Wiechmann T; Klengel T; Makotkine I; Binder EB; Yehuda R -
The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls.
Biol Psychiatry Volume: 88 Page(s): 169 - 184
07/15/2020 Authors: Coleman JRI; Gaspar HA; Bryois J; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Breen G -
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank.
Mol Psychiatry Volume: 25 Page(s): 1430 - 1446
07/01/2020 Authors: Coleman JRI; Peyrot WJ; Purves KL; Davis KAS; Rayner C; Choi SW; Hbel C; Gaspar HA; Kan C; Van der Auwera S -
A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression.
Mol Psychiatry Volume: 25 Page(s): 1312 - 1322
06/01/2020 Authors: Wei YB; McCarthy M; Ren H; Carrillo-Roa T; Shekhtman T; DeModena A; Liu JJ; Leckband SG; Mors O; Rietschel M -
Glucocorticoids as Mediators of Adverse Outcomes of Prenatal Stress.
Trends Neurosci Volume: 43 Page(s): 394 - 405
06/01/2020 Authors: Krontira AC; Cruceanu C; Binder EB -
No robust differences in fear conditioning between patients with fear-related disorders and healthy controls.
Behav Res Ther Volume: 129 Page(s): 103610
06/01/2020 Authors: Phlchen D; Leuchs L; Binder FP; Blaskovich B; Nantawisarakul T; Topalidis P; Brckl TM; Norrholm SD; Jovanovic T; BeCOME working group -
The biological classification of mental disorders (BeCOME) study: a protocol for an observational deep-phenotyping study for the identification of biological subtypes.
BMC Psychiatry Volume: 20 Page(s): 213
05/11/2020 Authors: Brckl TM; Spoormaker VI; Smann PG; Brem A-K; Henco L; Czamara D; Elbau I; Grandi NC; Jollans L; Khnel A -
A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank.
Nat Commun Volume: 11 Page(s): 2301
05/08/2020 Authors: Shen X; Howard DM; Adams MJ; Hill WD; Clarke T-K; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Deary IJ; Whalley HC; McIntosh AM -
A genome-wide association study identifies key modulators of complement factor H binding to malondialdehyde-epitopes.
Proc Natl Acad Sci U S A Volume: 117 Page(s): 9942 - 9951
05/05/2020 Authors: Alic L; Papac-Milicevic N; Czamara D; Rudnick RB; Ozsvar-Kozma M; Hartmann A; Gurbisz M; Hoermann G; Haslinger-Hutter S; Zipfel PF -
Cord blood DNA methylation reflects cord blood C-reactive protein levels but not maternal levels: a longitudinal study and meta-analysis.
Clin Epigenetics Volume: 12 Page(s): 60
04/30/2020 Authors: Yeung EH; Guan W; Zeng X; Salas LA; Mumford SL; de Prado Bert P; van Meel ER; Malmberg A; Sunyer J; Duijts L -
Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age.
Genome Med Volume: 12 Page(s): 25
03/02/2020 Authors: Merid SK; Novoloaca A; Sharp GC; Kpers LK; Kho AT; Roy R; Gao L; Annesi-Maesano I; Jain P; Plusquin M -
Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression.
Biol Psychiatry Volume: 87 Page(s): 419 - 430
03/01/2020 Authors: Glanville KP; Coleman JRI; Hanscombe KB; Euesden J; Choi SW; Purves KL; Breen G; Air TM; Andlauer TFM; Baune BT -
DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning.
PLoS Comput Biol Volume: 16 Page(s): e1007616
02/01/2020 Authors: Arloth J; Eraslan G; Andlauer TFM; Martins J; Iurato S; Khnel B; Waldenberger M; Frank J; Gold R; Hemmer B -
The AURORA Study: a longitudinal, multimodal library of brain biology and function after traumatic stress exposure.
Mol Psychiatry Volume: 25 Page(s): 283 - 296
02/01/2020 Authors: McLean SA; Ressler K; Koenen KC; Neylan T; Germine L; Jovanovic T; Clifford GD; Zeng D; An X; Linnstaedt S -
2019 Articles of Import and Impact.
Am J Psychiatry Volume: 177 Page(s): 17 - 19
01/01/2020 Authors: Kalin NH; Binder E; Brady KT; Lewis DA; Pine DS; Rodriguez C; Trivedi M; Rosenberg S -
Investigation of MORC1 DNA methylation as biomarker of early life stress and depressive symptoms.
J Psychiatr Res Volume: 120 Page(s): 154 - 162
01/01/2020 Authors: Thomas M; Coope A; Falkenberg C; Dunlop BW; Czamara D; Provencal N; Craighead WE; Mayberg HS; Nemeroff CB; Binder EB -
Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium.
Diabetes Care Volume: 43 Page(s): 98 - 105
01/01/2020 Authors: Howe CG; Cox B; Fore R; Jungius J; Kvist T; Lent S; Miles HE; Salas LA; Rifas-Shiman S; Starling AP -
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.
Cell Volume: 179 Page(s): 1469 - 1482.e11
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Epigenetics and depression.
Dialogues Clin Neurosci Volume: 21 Page(s): 397 - 405
12/01/2019 Authors: Penner-Goeke S; Binder EB -
A Role of Oxytocin Receptor Gene Brain Tissue Expression Quantitative Trait Locus rs237895 in the Intergenerational Transmission of the Effects of Maternal Childhood Maltreatment.
J Am Acad Child Adolesc Psychiatry Volume: 58 Page(s): 1207 - 1216
12/01/2019 Authors: Toepfer P; O'Donnell KJ; Entringer S; Heim CM; Lin DTS; MacIsaac JL; Kobor MS; Meaney MJ; Provenal N; Binder EB -
Exposure-induced changes of plasma metabolome and gene expression in patients with panic disorder.
Depress Anxiety Volume: 36 Page(s): 1173 - 1181
12/01/2019 Authors: Martins J; Czamara D; Lange J; Dethloff F; Binder EB; Turck CW; Erhardt A -
Stable longitudinal associations of family income with children's hippocampal volume and memory persist after controlling for polygenic scores of educational attainment.
Dev Cogn Neurosci Volume: 40 Page(s): 100720
12/01/2019 Authors: Raffington L; Czamara D; Mohn JJ; Falck J; Schmoll V; Heim C; Binder EB; Shing YL -
Identification of neurobehavioural symptom groups based on shared brain mechanisms.
Nat Hum Behav Volume: 3 Page(s): 1306 - 1318
12/01/2019 Authors: Ing A; Smann PG; Chu C; Tay N; Biondo F; Robert G; Jia T; Wolfers T; Desrivires S; Banaschewski T -
Pharmacogenomics-Driven Prediction of Antidepressant Treatment Outcomes: A Machine-Learning Approach With Multi-trial Replication.
Clin Pharmacol Ther Volume: 106 Page(s): 855 - 865
10/01/2019 Authors: Athreya AP; Neavin D; Carrillo-Roa T; Skime M; Biernacka J; Frye MA; Rush AJ; Wang L; Binder EB; Iyer RK -
Polygenic Risk Scores in Schizophrenia: Ready for the Real World?
Am J Psychiatry Volume: 176 Page(s): 783 - 784
10/01/2019 Authors: Binder EB -
Genetics of Resilience: Gene-by-Environment Interaction Studies as a Tool to Dissect Mechanisms of Resilience.
Biol Psychiatry Volume: 86 Page(s): 433 - 442
09/15/2019 Authors: Elbau IG; Cruceanu C; Binder EB -
Immediate biological embedding of maltreatment in children: Moderating effects of FK506 binding protein 5 (FKBP5) gene on cortisol reactivity and amygdala volume in children aged 3-5 years
Volume: 107 Page(s): 64 - 64
09/01/2019 Authors: Overfeld J; Buss C; de Punder K; Winter S-M; Haynes J-D; Binder EB; Heim C -
Childhood maltreatment severity is associated with smaller total brain size in preschool age children
Volume: 107 Page(s): 5 - 6
09/01/2019 Authors: Overfeld J; Buss C; de Punder K; Winter S-M; Haynes J-D; Binder E; Heim C -
Maternal prenatal depression and infant DNA methylome maturation: Developmental regulation of DNA methylation and relevance for infant behavior
Volume: 107 Page(s): 80 - 81
09/01/2019 Authors: Toepfer P; Pokhvisneva I; Garg E; Entringer S; Heim CM; Kobor MS; Provencal N; Binder EB; Wadhwa PD; Meaney MJ -
Evidence for oestrogen sensitivity in perinatal depression: pharmacological sex hormone manipulation study.
Br J Psychiatry Volume: 215 Page(s): 519 - 527
09/01/2019 Authors: Mehta D; Rex-Haffner M; Sndergaard HB; Pinborg A; Binder EB; Frokjaer VG -
Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns.
Hypertension Volume: 74 Page(s): 375 - 383
08/01/2019 Authors: Kazmi N; Sharp GC; Reese SE; Vehmeijer FO; Lahti J; Page CM; Zhang W; Rifas-Shiman SL; Rezwan FI; Simpkin AJ -
GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.
Am J Psychiatry Volume: 176 Page(s): 651 - 660
08/01/2019 Authors: Mullins N; Bigdeli TB; Brglum AD; Coleman JRI; Demontis D; Mehta D; Power RA; Ripke S; Stahl EA; Starnawska A -
Neurobiology of Self-Regulation: Longitudinal Influence of FKBP5 and Intimate Partner Violence on Emotional and Cognitive Development in Childhood.
Am J Psychiatry Volume: 176 Page(s): 626 - 634
08/01/2019 Authors: Halldorsdottir T; Kurtoic D; Mller-Myhsok B; Binder EB; Blair C -
Interactions between FKBP5 variation and environmental stressors in adolescent Major Depression.
Psychoneuroendocrinology Volume: 106 Page(s): 28 - 37
08/01/2019 Authors: Piechaczek CE; Greimel E; Feldmann L; Pehl V; Allgaier A-K; Frey M; Freisleder FJ; Halldorsdottir T; Binder EB; Ising M -
Polygenic Risk: Predicting Depression Outcomes in Clinical and Epidemiological Cohorts of Youths.
Am J Psychiatry Volume: 176 Page(s): 615 - 625
08/01/2019 Authors: Halldorsdottir T; Piechaczek C; Soares de Matos AP; Czamara D; Pehl V; Wagenbuechler P; Feldmann L; Quickenstedt-Reinhardt P; Allgaier A-K; Freisleder FJ -
Glucocorticoid-induced leucine zipper "quantifies" stressors and increases male susceptibility to PTSD.
Transl Psychiatry Volume: 9 Page(s): 178
07/25/2019 Authors: Lebow MA; Schroeder M; Tsoory M; Holzman-Karniel D; Mehta D; Ben-Dor S; Gil S; Bradley B; Smith AK; Jovanovic T -
Genome-wide gene expression in a pharmacological hormonal transition model and its relation to depressive symptoms.
Acta Psychiatr Scand Volume: 140 Page(s): 77 - 84
07/01/2019 Authors: Mehta D; Rex-Haffner M; Sndergaard HB; Pinborg A; Binder EB; Frokjaer VG -
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns.
Nat Commun Volume: 10 Page(s): 2548
06/11/2019 Authors: Czamara D; Eraslan G; Page CM; Lahti J; Lahti-Pulkkinen M; Hmlinen E; Kajantie E; Laivuori H; Villa PM; Reynolds RM -
Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-B-driven inflammation and cardiovascular risk.
Proc Natl Acad Sci U S A Volume: 116 Page(s): 11370 - 11379
06/04/2019 Authors: Zannas AS; Jia M; Hafner K; Baumert J; Wiechmann T; Pape JC; Arloth J; Kdel M; Martinelli S; Roitman M -
Epigenome-wide meta-analysis of DNA methylation and childhood asthma.
J Allergy Clin Immunol Volume: 143 Page(s): 2062 - 2074
06/01/2019 Authors: Reese SE; Xu C-J; den Dekker HT; Lee MK; Sikdar S; Ruiz-Arenas C; Merid SK; Rezwan FI; Page CM; Ullemar V -
Chronic adolescent stress sex-specifically alters the hippocampal transcriptome in adulthood.
Neuropsychopharmacology Volume: 44 Page(s): 1207 - 1215
06/01/2019 Authors: Rowson SA; Bekhbat M; Kelly SD; Binder EB; Hyer MM; Shaw G; Bent MA; Hodes G; Tharp G; Weinshenker D -
Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus.
Clin Epigenetics Volume: 11 Page(s): 83
05/23/2019 Authors: Wiechmann T; Rh S; Sauer S; Czamara D; Arloth J; Kdel M; Beintner M; Knop L; Menke A; Binder EB -
Dynamic DNA methylation changes in the maternal oxytocin gene locus (OXT) during pregnancy predict postpartum maternal intrusiveness.
Psychoneuroendocrinology Volume: 103 Page(s): 156 - 162
05/01/2019 Authors: Toepfer P; O'Donnell KJ; Entringer S; Garg E; Heim CM; Lin DTS; MacIsaac JL; Kobor MS; Meaney MJ; Provenal N -
Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium.
Psychol Med Volume: 49 Page(s): 1218 - 1226
05/01/2019 Authors: Polimanti R; Peterson RE; Ong J-S; MacGregor S; Edwards AC; Clarke T-K; Frank J; Gerring Z; Gillespie NA; Lind PA -
Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.
Nat Commun Volume: 10 Page(s): 1893
04/23/2019 Authors: Kpers LK; Monnereau C; Sharp GC; Yousefi P; Salas LA; Ghantous A; Page CM; Reese SE; Wilcox AJ; Czamara D -
The effects of childhood maltreatment on epigenetic regulation of stress-response associated genes: an intergenerational approach.
Sci Rep Volume: 9 Page(s): 983
04/18/2019 Authors: Ramo-Fernndez L; Boeck C; Koenig AM; Schury K; Binder EB; Gndel H; Fegert JM; Karabatsiakis A; Kolassa I-T -
Screening for coeliac disease in 1624 mainly asymptomatic children with type 1 diabetes: is genotyping for coeliac-specific human leucocyte antigen the right approach?
Arch Dis Child Volume: 104 Page(s): 354 - 359
04/01/2019 Authors: Binder E; Rohrer T; Denzer C; Marg W; Ohlenschlger U; Schenk-Huber H; Schierloh U; Skopnik H; Frhlich-Reiterer EE; Holl RW -
Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study.
JAMA Psychiatry Volume: 76 Page(s): 399 - 408
04/01/2019 Authors: Choi KW; Chen C-Y; Stein MB; Klimentidis YC; Wang M-J; Koenen KC; Smoller JW; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium -
Identification of common genetic risk variants for autism spectrum disorder.
Nat Genet Volume: 51 Page(s): 431 - 444
03/01/2019 Authors: Grove J; Ripke S; Als TD; Mattheisen M; Walters RK; Won H; Pallesen J; Agerbo E; Andreassen OA; Anney R -
[Environment and epigenetics].
Nervenarzt Volume: 90 Page(s): 107 - 113
02/01/2019 Authors: Binder EB -
Stress dynamically regulates co-expression networks of glucocorticoid receptor-dependent MDD and SCZ risk genes.
Transl Psychiatry Volume: 9 Page(s): 41
01/29/2019 Authors: Zimmermann CA; Arloth J; Santarelli S; Lschner A; Weber P; Schmidt MV; Spengler D; Binder EB -
INTERACTIONS BETWEEN GENOTYPE AND ENVIRONMENT HAVE A STRONG EFFECT ON VARIABILITY IN DNA METHYLATION IN PSYCHIATRIC PATIENTS
Volume: 29 Page(s): S984 - S984
01/01/2019 Authors: Awaloff Y; Provencal N; Carrillo-Roa T; Halldorsdottir T; Boadie D; Mayberg H; Craighed E; Czamara D; Binder E -
THE EPIGENETIC CLOCK AT BIRTH: ASSOCIATIONS WITH MATERNAL ANTENATAL DEPRESSION AND CHILD PSYCHIATRIC PROBLEMS
Volume: 29 Page(s): S748 - S748
01/01/2019 Authors: Raikkonen K; Suarez A; Lahti J; Czamara D; Lahti M; Knight A; Girchenko P; Hamalainen E; Kajantie E; Laivuori H -
Symptoms are not the solution but the problem: Why psychiatric research should focus on processes rather than symptoms.
Behav Brain Sci Volume: 42 Page(s): e7
01/01/2019 Authors: Elbau IG; Binder EB; Spoormaker VI -
Epigenetic Modifications in Stress Response Genes Associated With Childhood Trauma.
Front Psychiatry Volume: 10 Page(s): 808
01/01/2019 Authors: Jiang S; Postovit L; Cattaneo A; Binder EB; Aitchison KJ -
DNA methylation levels are associated with CRF1 receptor antagonist treatment outcome in women with post-traumatic stress disorder.
Clin Epigenetics Volume: 10 Page(s): 136
11/03/2018 Authors: Pape JC; Carrillo-Roa T; Rothbaum BO; Nemeroff CB; Czamara D; Zannas AS; Iosifescu D; Mathew SJ; Neylan TC; Mayberg HS -
FoxO1, A2M, and TGF-1: three novel genes predicting depression in gene X environment interactions are identified using cross-species and cross-tissues transcriptomic and miRNomic analyses.
Mol Psychiatry Volume: 23 Page(s): 2192 - 2208
11/01/2018 Authors: Cattaneo A; Cattane N; Malpighi C; Czamara D; Suarez A; Mariani N; Kajantie E; Luoni A; Eriksson JG; Lahti J -
The brain's hemodynamic response function rapidly changes under acute psychosocial stress in association with genetic and endocrine stress response markers.
Proc Natl Acad Sci U S A Volume: 115 Page(s): E10206 - E10215
10/23/2018 Authors: Elbau IG; Brcklmeier B; Uhr M; Arloth J; Czamara D; Spoormaker VI; Czisch M; Stephan KE; Binder EB; Smann PG -
Response rate profiles for major depressive disorder: Characterizing early response and longitudinal nonresponse.
Depress Anxiety Volume: 35 Page(s): 992 - 1000
10/01/2018 Authors: Kelley ME; Dunlop BW; Nemeroff CB; Lori A; Carrillo-Roa T; Binder EB; Kutner MH; Rivera VA; Craighead WE; Mayberg HS -
The Role of m6A/m-RNA Methylation in Stress Response Regulation.
Neuron Volume: 99 Page(s): 389 - 403.e9
07/25/2018 Authors: Engel M; Eggert C; Kaplick PM; Eder M; Rh S; Tietze L; Namendorf C; Arloth J; Weber P; Rex-Haffner M -
The epigenetic clock and pubertal, neuroendocrine, psychiatric, and cognitive outcomes in adolescents.
Clin Epigenetics Volume: 10 Page(s): 96
07/18/2018 Authors: Suarez A; Lahti J; Czamara D; Lahti-Pulkkinen M; Girchenko P; Andersson S; Strandberg TE; Reynolds RM; Kajantie E; Binder EB -
Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium.
Biol Psychiatry Volume: 84 Page(s): 138 - 147
07/15/2018 Authors: Peyrot WJ; Van der Auwera S; Milaneschi Y; Dolan CV; Madden PAF; Sullivan PF; Strohmaier J; Ripke S; Rietschel M; Nivard MG -
HAM-TBS: high-accuracy methylation measurements via targeted bisulfite sequencing.
Epigenetics Chromatin Volume: 11 Page(s): 39
07/04/2018 Authors: Roeh S; Wiechmann T; Sauer S; Kdel M; Binder EB; Provenal N -
More Research Needed on the Association Between Genotype and Antidepressant Response: Response to Fabbri et al (vol 175, pg 576, 2018)
AMERICAN JOURNAL OF PSYCHIATRY Volume: 175 Page(s): 685 - 685
07/01/2018 Authors: O'Connell CP; Goldstein-Piekarski AN; Nemeroff CB; Schatzberg AF; Debattista C; Carrillo-Roa T; Binder EB; Dunlop BW; Craighead WE; Mayberg HS -
Would Addressing Alcohol Consumption Further Account for Variance in Methylation?
Am J Psychiatry Volume: 175 Page(s): 684 - 685
07/01/2018 Authors: Philibert RA; Beach SRH -
Intergenerational geneenvironment interaction of FKBP5 and childhood maltreatment on hair steroids.
Psychoneuroendocrinology Volume: 92 Page(s): 103 - 112
06/01/2018 Authors: Koenig AM; Ramo-Fernndez L; Boeck C; Umlauft M; Pauly M; Binder EB; Kirschbaum C; Gndel H; Karabatsiakis A; Kolassa I-T -
Correction to: Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling.
Genome Biol Volume: 19 Page(s): 61
05/23/2018 Authors: Zannas AS; Arloth J; Carrillo-Roa T; Iurato S; Rh S; Ressler KJ; Nemeroff CB; Smith AK; Bradley B; Heim C -
Understanding the Molecular Mechanisms Underpinning Gene by Environment Interactions in Psychiatric Disorders: The FKBP5 Model.
Biol Psychiatry Volume: 83 Page(s): 821 - 830
05/15/2018 Authors: Matosin N; Halldorsdottir T; Binder EB -
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.
Nat Genet Volume: 50 Page(s): 668 - 681
05/01/2018 Authors: Wray NR; Ripke S; Mattheisen M; Trzaskowski M; Byrne EM; Abdellaoui A; Adams MJ; Agerbo E; Air TM; Andlauer TMF -
The Epigenetic Clock at Birth: Associations With Maternal Antenatal Depression and Child Psychiatric Problems.
J Am Acad Child Adolesc Psychiatry Volume: 57 Page(s): 321 - 328.e2
05/01/2018 Authors: Suarez A; Lahti J; Czamara D; Lahti-Pulkkinen M; Knight AK; Girchenko P; Hmlinen E; Kajantie E; Lipsanen J; Laivuori H -
Epigenetic Biomarkers in Women With Posttraumatic Stress Disorder After CRF1 Receptor Antagonist Treatment
Volume: 83 Page(s): S308 - S308
05/01/2018 Authors: Pape J; Carrillo-Roa T; Wiechmann T; Roeh S; Rothbaum B; Nemeroff C; Czamara D; Zannas A; Iosifescu D; Mathew S -
Polygenic Risk: Predicting Depressive Symptoms in Clinical and Epidemiological Cohorts of Adolescents
Volume: 83 Page(s): S262 - S262
05/01/2018 Authors: Halldorsdottir T; Piechaczek C; Pehl V; Wagenbuechler P; Greimel E; Soares de Matos AP; Feldmann L; Quickenstedt-Reinhardt P; Allgaier A-K; Czamara D -
Antidepressant Outcomes Predicted by Genetic Variation in Corticotropin-Releasing Hormone Binding Protein.
Am J Psychiatry Volume: 175 Page(s): 251 - 261
03/01/2018 Authors: O'Connell CP; Goldstein-Piekarski AN; Nemeroff CB; Schatzberg AF; Debattista C; Carrillo-Roa T; Binder EB; Dunlop BW; Craighead WE; Mayberg HS -
Sex-related differential response to dexamethasone in endocrine and immune measures in depressed in-patients and healthy controls.
J Psychiatr Res Volume: 98 Page(s): 107 - 115
03/01/2018 Authors: Rampp C; Eichelkraut A; Best J; Czamara D; Rex-Haffner M; Uhr M; Binder EB; Menke A -
Estrogen-dependent association of HDAC4 with fear in female mice and women with PTSD.
Mol Psychiatry Volume: 23 Page(s): 658 - 665
03/01/2018 Authors: Maddox SA; Kilaru V; Shin J; Jovanovic T; Almli LM; Dias BG; Norrholm SD; Fani N; Michopoulos V; Ding Z -
Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood.
Mol Psychiatry Volume: 23 Page(s): 533 - 543
03/01/2018 Authors: Dedic N; Phlmann ML; Richter JS; Mehta D; Czamara D; Metzger MW; Dine J; Bedenk BT; Hartmann J; Wagner KV -
Complications With Insulin Pump Therapy vs Insulin Injection Therapy-Reply.
JAMA Volume: 319 Page(s): 503 - 504
02/06/2018 Authors: Karges B; Binder E; Rosenbauer J -
Accelerated DNA methylation aging and increased resilience in veterans: The biological cost for soldiering on.
Neurobiol Stress Volume: 8 Page(s): 112 - 119
02/01/2018 Authors: Mehta D; Bruenig D; Lawford B; Harvey W; Carrillo-Roa T; Morris CP; Jovanovic T; Young RM; Binder EB; Voisey J -
A DNA methylation biomarker of alcohol consumption.
Mol Psychiatry Volume: 23 Page(s): 422 - 433
02/01/2018 Authors: Liu C; Marioni RE; Hedman K; Pfeiffer L; Tsai P-C; Reynolds LM; Just AC; Duan Q; Boer CG; Tanaka T -
Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium.
Int J Epidemiol Volume: 47 Page(s): 22 - 23u
02/01/2018 Authors: Felix JF; Joubert BR; Baccarelli AA; Sharp GC; Almqvist C; Annesi-Maesano I; Arshad H; Baz N; Bakermans-Kranenburg MJ; Bakulski KM -
PTSD Blood Transcriptome Mega-Analysis: Shared Inflammatory Pathways across Biological Sex and Modes of Trauma.
Neuropsychopharmacology Volume: 43 Page(s): 469 - 481
02/01/2018 Authors: Breen MS; Tylee DS; Maihofer AX; Neylan TC; Mehta D; Binder EB; Chandler SD; Hess JL; Kremen WS; Risbrough VB -
Hsp90 and FKBP51: complex regulators of psychiatric diseases.
Philos Trans R Soc Lond B Biol Sci Volume: 373
01/19/2018 Authors: Criado-Marrero M; Rein T; Binder EB; Porter JT; Koren J; Blair LJ -
Polymorphism in Tmem132d regulates expression and anxiety-related behavior through binding of RNA polymerase II complex.
Transl Psychiatry Volume: 8 Page(s): 1
01/10/2018 Authors: Naik RR; Sotnikov SV; Diepold RP; Iurato S; Markt PO; Bultmann A; Brehm N; Mattheus T; Lutz B; Erhardt A -
Anxiety Associated Increased CpG Methylation in the Promoter of Asb1: A Translational Approach Evidenced by Epidemiological and Clinical Studies and a Murine Model.
Neuropsychopharmacology Volume: 43 Page(s): 342 - 353
01/01/2018 Authors: Emeny RT; Baumert J; Zannas AS; Kunze S; Wahl S; Iurato S; Arloth J; Erhardt A; Balsevich G; Schmidt MV -
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.
Commun Biol Volume: 1 Page(s): 163
01/01/2018 Authors: de Jong S; Diniz MJA; Saloma A; Gadelha A; Santoro ML; Ota VK; Noto C; Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium; Curtis C; Newhouse SJ -
Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder.
PLoS One Volume: 13 Page(s): e0209160
01/01/2018 Authors: Arnau-Soler A; Adams MJ; Generation Scotland; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Hayward C; Thomson PA -
"DNA Methylation signatures in panic disorder".
Transl Psychiatry Volume: 7 Page(s): 1287
12/18/2017 Authors: Iurato S; Carrillo-Roa T; Arloth J; Czamara D; Diener-Hlzl L; Lange J; Mller-Myhsok B; Binder EB; Erhardt A -
Corticotropin-Releasing Factor Receptor 1 Antagonism Is Ineffective for Women With Posttraumatic Stress Disorder.
Biol Psychiatry Volume: 82 Page(s): 866 - 874
12/15/2017 Authors: Dunlop BW; Binder EB; Iosifescu D; Mathew SJ; Neylan TC; Pape JC; Carrillo-Roa T; Green C; Kinkead B; Grigoriadis D -
An epigenome-wide association study meta-analysis of educational attainment.
Mol Psychiatry Volume: 22 Page(s): 1680 - 1690
12/01/2017 Authors: Karlsson Linnr R; Marioni RE; Rietveld CA; Simpkin AJ; Davies NM; Watanabe K; Armstrong NJ; Auro K; Baumbach C; Bonder MJ -
Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity.
PLoS Biol Volume: 15 Page(s): e2002690
12/01/2017 Authors: Carrillo-Roa T; Labermaier C; Weber P; Herzog DP; Lareau C; Santarelli S; Wagner KV; Rex-Haffner M; Harbich D; Scharf SH -
Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations.
JAMA Psychiatry Volume: 74 Page(s): 1214 - 1225
12/01/2017 Authors: Milaneschi Y; Lamers F; Peyrot WJ; Baune BT; Breen G; Dehghan A; Forstner AJ; Grabe HJ; Homuth G; Kan C -
Early life stress, FK506 binding protein 5 gene (FKBP5) methylation, and inhibition-related prefrontal function: A prospective longitudinal study.
Dev Psychopathol Volume: 29 Page(s): 1895 - 1903
12/01/2017 Authors: Harms MB; Birn R; Provencal N; Wiechmann T; Binder EB; Giakas SW; Roeber BJ; Pollak SD -
[Not Available].
Drug Res (Stuttg) Volume: 67 Page(s): S25
11/01/2017 Authors: Binder E -
Genomewide DNA methylation analysis in combat veterans reveals a novel locus for PTSD.
Acta Psychiatr Scand Volume: 136 Page(s): 493 - 505
11/01/2017 Authors: Mehta D; Bruenig D; Carrillo-Roa T; Lawford B; Harvey W; Morris CP; Smith AK; Binder EB; Young RM; Voisey J -
Association of Insulin Pump Therapy vs Insulin Injection Therapy With Severe Hypoglycemia, Ketoacidosis, and Glycemic Control Among Children, Adolescents, and Young Adults With Type 1 Diabetes.
JAMA Volume: 318 Page(s): 1358 - 1366
10/10/2017 Authors: Karges B; Schwandt A; Heidtmann B; Kordonouri O; Binder E; Schierloh U; Boettcher C; Kapellen T; Rosenbauer J; Holl RW -
Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia.
EMBO J Volume: 36 Page(s): 2815 - 2828
10/02/2017 Authors: Ags-Balboa RC; Pinheiro PS; Rebola N; Kerimoglu C; Benito E; Gertig M; Bahari-Javan S; Jain G; Burkhardt S; Delalle I -
Epigenetic age at birth an prenatal risk factors
Volume: 124 Page(s): 1290 - 1291
10/01/2017 Authors: Raikkonen K; Girchenko P; Suarez A; Lahti J; Czamara D; Lahti M; Knight AK; Hamalainen E; Kajantie E; Laivuori H -
Cohort Profile: Prediction and prevention of preeclampsia and intrauterine growth restriction (PREDO) study.
Int J Epidemiol Volume: 46 Page(s): 1380 - 1381g
10/01/2017 Authors: Girchenko P; Lahti M; Tuovinen S; Savolainen K; Lahti J; Binder EB; Reynolds RM; Entringer S; Buss C; Wadhwa PD -
Epigenetic effects of glucocorticoids exposure during hippocampal neurogenesis and their implication in psychiatric disorders
Volume: 27 Page(s): S553 - S553
10/01/2017 Authors: Provencal N; Arloth J; Cattaneo A; Anacker C; Klengel T; Pariante C; Binder E -
POLYGENIC SCORES DERIVED FROM NEUROIMAGING ENDOPHENOTYPES PREDICT OUTCOMES TO PSYCHOTHERAPY AND MEDICATION TREATMENTS FOR MAJOR DEPRESSIVE DISORDER
Volume: 27 Page(s): S486 - S486
10/01/2017 Authors: Carrillo-Roa T; Boadie D; McGrath C; Mueller-Myhsok B; Craighed E; Mayberg H; Binder E -
FKBP5 moderation of the relationship between childhood trauma and maladaptive emotion regulation strategies in adolescents.
Psychoneuroendocrinology Volume: 84 Page(s): 61 - 65
10/01/2017 Authors: Halldorsdottir T; de Matos APS; Awaloff Y; Arnarson E; Craighead WE; Binder EB -
Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment.
Mol Psychiatry Volume: 22 Page(s): 1155 - 1163
08/01/2017 Authors: Juki MM; Opel N; Strm J; Carrillo-Roa T; Miksys S; Novalen M; Renblom A; Sim SC; Peas-Lled EM; Courtet P -
Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment.
Mol Psychiatry Volume: 22 Page(s): 1224
08/01/2017 Authors: Juki MM; Opel N; Strm J; Carrillo-Roa T; Miksys S; Novalen M; Renblom A; Sim SC; Peas-Lled EM; Courtet P -
Sequencing on the SOLiD 5500xl System - in-depth characterization of the GC bias.
Nucleus Volume: 8 Page(s): 370 - 380
07/04/2017 Authors: Roeh S; Weber P; Rex-Haffner M; Deussing JM; Binder EB; Jakovcevski M -
Genotyping of coeliac-specific human leucocyte antigen in children with type 1 diabetes: does this screening method make sense?
Arch Dis Child Volume: 102 Page(s): 603 - 606
07/01/2017 Authors: Binder E; Loinger M; Mhlbacher A; Edlinger M; Steichen E; Meraner D; Loacker L; Weigel G; Mller T; Frhlich-Reiterer E -
DNA Methylation Biomarkers and Treatment Effects of a Corticotropin Releasing Hormone Type 1 Receptor Antagonist in a Biologically-Defined Subset of PTSD-Patients
Volume: 81 Page(s): S222 - S222
05/15/2017 Authors: Pape J; Carrillo-Roa T; Iosifescu D; Mathew S; Neylan T; Nemeroff C; Mayberg H; Dunlop B; Binder E -
Transcriptome-wide Analysis Identified Differential Expression of PID1, a Gene Implicated in Insulin Resistance, in High versus Low Psychological Resilience
Volume: 81 Page(s): S94 - S95
05/15/2017 Authors: Wingo A; Lori A; Gillespie C; Kerley K; Jovanovic T; Binder E; Bradley B; Ressler K -
Genome-wide association study of positive emotion identifies a genetic variant and a role for microRNAs.
Mol Psychiatry Volume: 22 Page(s): 774 - 783
05/01/2017 Authors: Wingo AP; Almli LM; Stevens JS; Jovanovic T; Wingo TS; Tharp G; Li Y; Lori A; Briscione M; Jin P -
A peripheral epigenetic signature of immune system genes is linked to neocortical thickness and memory.
Nat Commun Volume: 8 Page(s): 15193
04/26/2017 Authors: Freytag V; Carrillo-Roa T; Milnik A; Smann PG; Vukojevic V; Coynel D; Demougin P; Egli T; Gschwind L; Jessen F -
An adverse early life environment can enhance stress resilience in adulthood.
Psychoneuroendocrinology Volume: 78 Page(s): 213 - 221
04/01/2017 Authors: Santarelli S; Zimmermann C; Kalideris G; Lesuis SL; Arloth J; Uribe A; Dournes C; Balsevich G; Hartmann J; Masana M -
Understanding geneearly adversity interactions: possibilities for insight in the biology of psychiatric disorders.
Eur Arch Psychiatry Clin Neurosci Volume: 267 Page(s): 183 - 185
04/01/2017 Authors: Binder EB -
Life stress, glucocorticoid signaling, and the aging epigenome: Implications for aging-related diseases.
Neurosci Biobehav Rev Volume: 74 Page(s): 356 - 365
03/01/2017 Authors: Gassen NC; Chrousos GP; Binder EB; Zannas AS -
Oxytocin pathways in the intergenerational transmission of maternal early life stress.
Neurosci Biobehav Rev Volume: 73 Page(s): 293 - 308
02/01/2017 Authors: Toepfer P; Heim C; Entringer S; Binder E; Wadhwa P; Buss C -
Preclinical and Clinical Evidence of DNA Methylation Changes in Response to Trauma and Chronic Stress.
Chronic Stress (Thousand Oaks) Volume: 1
02/01/2017 Authors: Matosin N; Cruceanu C; Binder EB -
Gene Environment Interactions: From Molecular Mechanisms to Behavior.
Annu Rev Psychol Volume: 68 Page(s): 215 - 241
01/03/2017 Authors: Halldorsdottir T; Binder EB -
Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth.
Clin Epigenetics Volume: 9 Page(s): 49
01/01/2017 Authors: Girchenko P; Lahti J; Czamara D; Knight AK; Jones MJ; Suarez A; Hmlinen E; Kajantie E; Laivuori H; Villa PM -
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.
Genome Biol Volume: 17 Page(s): 255
12/12/2016 Authors: Ligthart S; Marzi C; Aslibekyan S; Mendelson MM; Conneely KN; Tanaka T; Colicino E; Waite LL; Joehanes R; Guan W -
Functional Impact of An ADHD-Associated DIRAS2 Promoter Polymorphism.
Neuropsychopharmacology Volume: 41 Page(s): 3025 - 3031
12/01/2016 Authors: Grnewald L; Landaas ET; Geissler J; Weber H; Quast C; Rh S; Schartner C; Lesch K-P; Romanos M; Kittel-Schneider S -
Prioritizing individual genetic variants after kernel machine testing using variable selection.
Genet Epidemiol Volume: 40 Page(s): 722 - 731
12/01/2016 Authors: He Q; Cai T; Liu Y; Zhao N; Harmon QE; Almli LM; Binder EB; Engel SM; Ressler KJ; Conneely KN -
Reply to: mitochondrial diabetes in Germany and Austria.
Eur J Pediatr Volume: 175 Page(s): 2025 - 2026
12/01/2016 Authors: Reinauer C; Meissner T; Roden M; Thon A; Holterhus P-M; Haberland H; Binder E; Marg W; Bollow E; Holl R -
Epigenetic Signatures of Cigarette Smoking
CIRCULATION Volume: 134 Page(s): 1682 - 1682
11/22/2016 Authors: Joehanes R; Just AC; Marioni RE; Pilling LC; Reynolds LM; Mandaviya PR; Guan W; Xu T; Elks CE; Aslibekyan S -
Amygdalar MicroRNA-15a Is Essential for Coping with Chronic Stress.
Cell Rep Volume: 17 Page(s): 1882 - 1891
11/08/2016 Authors: Volk N; Pape JC; Engel M; Zannas AS; Cattane N; Cattaneo A; Binder EB; Chen A -
An epigenetic clock for gestational age at birth based on blood methylation data.
Genome Biol Volume: 17 Page(s): 206
10/07/2016 Authors: Knight AK; Craig JM; Theda C; Bkvad-Hansen M; Bybjerg-Grauholm J; Hansen CS; Hollegaard MV; Hougaard DM; Mortensen PB; Weinsheimer SM -
DNA methylation signatures of susceptibility to panic disorder
Volume: 26 Page(s): S611 - S611
10/01/2016 Authors: Iurato S; Carrillo-Roa T; Czamara D; Ising M; Lucae S; Binder EB; Erhardt A -
Investigating the Impact of a Genome-Wide Supported Bipolar Risk Variant of MAD1L1 on the Human Reward System.
Neuropsychopharmacology Volume: 41 Page(s): 2679 - 2687
10/01/2016 Authors: Trost S; Diekhof EK; Mohr H; Vieker H; Krmer B; Wolf C; Keil M; Dechent P; Binder EB; Gruber O -
The importance of understanding the biological mechanisms of trauma.
Acta Psychiatr Scand Volume: 134 Page(s): 279 - 280
10/01/2016 Authors: Binder EB -
Epigenetic Signatures of Cigarette Smoking.
Circ Cardiovasc Genet Volume: 9 Page(s): 436 - 447
10/01/2016 Authors: Joehanes R; Just AC; Marioni RE; Pilling LC; Reynolds LM; Mandaviya PR; Guan W; Xu T; Elks CE; Aslibekyan S -
A variation in the oxytocin receptor gene moderates the relationship between early maternal care in childhood and interleukin 6 (IL-6) concentrations during pregnancy
Volume: 71 Page(s): 15 - 15
09/01/2016 Authors: Toepfer P; Heim CM; Entringer S; Wadhwa PD; Provencal N; Binder EB; Buss C -
Maternal depression during pregnancy and epigenetic age in their newborns: The PREDO study
Volume: 71 Page(s): 63 - 63
09/01/2016 Authors: Suarez A; Lahti JMT; Girchenko P; Lahti M; Hamalainen E; Laivuori H; Kajantie E; Pesonen A-K; Villa PM; Reynolds RM -
Heritable epigenetic patterns of stress-responsive genes in traumatized children
PSYCHONEUROENDOCRINOLOGY Volume: 71 Page(s): 43 - 43
09/01/2016 Authors: Smith A; Kilaru V; Klengel T; Nishitani S; Binder E; Ressler K; Bradley B; Jovanovic T -
Stress vulnerability and epigenetic variation of SKA2, potential causes and consequences
PSYCHONEUROENDOCRINOLOGY Volume: 71 Page(s): 11 - 11
09/01/2016 Authors: Jones I; Clive M; Wilcox H; Eaton W; Van Eck K; Jovanovic T; Klengel T; Bradley B; Binder E; Geuze E -
Intergenerational effect of infant maltreatment on epigenetic and functional outcomes in rhesus monkeys
Volume: 71 Page(s): 42 - 42
09/01/2016 Authors: Klengel T; Howell B; Guzman D; Morin E; Binder E; Ressler K; Sanchez MM -
Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation.
Biol Psychiatry Volume: 80 Page(s): 372 - 380
09/01/2016 Authors: Yehuda R; Daskalakis NP; Bierer LM; Bader HN; Klengel T; Holsboer F; Binder EB -
Needle detachment in a slim and physically active child with insulin pump treatment.
Pediatr Diabetes Volume: 17 Page(s): 385 - 388
08/01/2016 Authors: Moser C; Maurer K; Binder E; Meraner D; Steichen E; Abt D; Freund-Unsinn K; Hofer SE -
Time-dependent effects of dexamethasone plasma concentrations on glucocorticoid receptor challenge tests.
Psychoneuroendocrinology Volume: 69 Page(s): 161 - 171
07/01/2016 Authors: Menke A; Arloth J; Best J; Namendorf C; Gerlach T; Czamara D; Lucae S; Dunlop BW; Crowe TM; Garlow SJ -
Oxytocin receptor DNA methylation in postpartum depression.
Psychoneuroendocrinology Volume: 69 Page(s): 150 - 160
07/01/2016 Authors: Kimmel M; Clive M; Gispen F; Guintivano J; Brown T; Cox O; Beckmann MW; Kornhuber J; Fasching PA; Osborne LM -
CREB1 Genotype Modulates Adaptive Reward-Based Decisions in Humans.
Cereb Cortex Volume: 26 Page(s): 2970 - 2981
07/01/2016 Authors: Wolf C; Mohr H; Diekhof EK; Vieker H; Goya-Maldonado R; Trost S; Krmer B; Keil M; Binder EB; Gruber O -
Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation.
J Allergy Clin Immunol Volume: 138 Page(s): 47 - 56
07/01/2016 Authors: Garn H; Bahn S; Baune BT; Binder EB; Bisgaard H; Chatila TA; Chavakis T; Culmsee C; Dannlowski U; Gay S -
Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation.
Sci Adv Volume: 2 Page(s): e1501678
06/01/2016 Authors: Andlauer TFM; Buck D; Antony G; Bayas A; Bechmann L; Berthele A; Chan A; Gasperi C; Gold R; Graetz C -
Genome-wide gene-based analysis suggests an association between Neuroligin 1 (NLGN1) and post-traumatic stress disorder.
Transl Psychiatry Volume: 6 Page(s): e820
05/24/2016 Authors: Kilaru V; Iyer SV; Almli LM; Stevens JS; Lori A; Jovanovic T; Ely TD; Bradley B; Binder EB; Koen N -
Candidate genes in panic disorder: meta-analyses of 23 common variants in major anxiogenic pathways.
Mol Psychiatry Volume: 21 Page(s): 665 - 679
05/01/2016 Authors: Howe AS; Buttenschn HN; Bani-Fatemi A; Maron E; Otowa T; Erhardt A; Binder EB; Gregersen NO; Mors O; Woldbye DP -
Replication of Epigenetic Postpartum Depression Biomarkers and Variation with Hormone Levels.
Neuropsychopharmacology Volume: 41 Page(s): 1648 - 1658
05/01/2016 Authors: Osborne L; Clive M; Kimmel M; Gispen F; Guintivano J; Brown T; Cox O; Judy J; Meilman S; Braier A -
Fluoxetine treatment prevents the inflammatory response in a mouse model of posttraumatic stress disorder.
J Psychiatr Res Volume: 76 Page(s): 74 - 83
05/01/2016 Authors: Kao C-Y; He Z; Zannas AS; Hahn O; Khne C; Reichel JM; Binder EB; Wotjak CT; Khaitovich P; Turck CW -
Analysis of Rare Variants in ADRA1a with Response to Treatment for Major Depressive Disorder (MDD)
Volume: 79 Page(s): 225S - 226S
05/01/2016 Authors: Lori A; Carillo-Roa T; Binder EB; Mayberg HS; McGrath CL; Mletzko T; Laird JL; Czamara D; Dunlop BW; Craighead WE -
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Aging and Major Depression Epigenetically Upregulate FKBP5: Impact on Peripheral Inflammation
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An Epigenetic Clock for Developmental Maturity at Birth
Volume: 79 Page(s): 123S - 123S
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An Integrative Disease-relevant Multi-omics Analysis to Predict Risk for Stress-related Psychiatric Disorders
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Intergenerational Effects of Infant Maltreatment on Epigenetic and Functional Outcomes in Rhesus Monkeys
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DNA Methylation Signatures of Susceptibility to Panic Disorder
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Low prevalence of patients with mitochondrial disease in the German/Austrian DPV diabetes registry.
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Novel Multiple Sclerosis Genetic Risk Factors Are Involved in Epigenetic Regulation
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Novel Multiple Sclerosis Genetic Risk Factors Are Involved in Epigenetic Regulation
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Gene-Stress-Epigenetic Regulation of FKBP5: Clinical and Translational Implications.
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Polygenic Predictors of Antidepressant Treatment-Specific Response
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A mega-analysis of genome-wide association studies for major depressive disorder.
Mol Psychiatry Volume: 18 Page(s): 497 - 511
04/01/2013 Authors: Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium; Ripke S; Wray NR; Lewis CM; Hamilton SP; Weissman MM; Breen G; Byrne EM; Blackwood DHR; Boomsma DI -
Allele-specific epigenetic modification: a molecular mechanism for gene-environment interactions in stress-related psychiatric disorders?
Epigenomics Volume: 5 Page(s): 109 - 112
04/01/2013 Authors: Klengel T; Binder EB -
Sex dependent influence of a functional polymorphism in steroid 5--reductase type 2 (SRD5A2) on post-traumatic stress symptoms.
Am J Med Genet B Neuropsychiatr Genet Volume: 162B Page(s): 283 - 292
04/01/2013 Authors: Gillespie CF; Almli LM; Smith AK; Bradley B; Kerley K; Crain DF; Mercer KB; Weiss T; Phifer J; Tang Y -
Gene environment interactions in the prediction of response to antidepressant treatment.
Int J Neuropsychopharmacol Volume: 16 Page(s): 701 - 711
04/01/2013 Authors: Klengel T; Binder EB -
Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression.
Genes Brain Behav Volume: 12 Page(s): 289 - 296
04/01/2013 Authors: Menke A; Klengel T; Rubel J; Brckl T; Pfister H; Lucae S; Uhr M; Holsboer F; Binder EB -
Use of biomarkers in the management of children with lupus.
Curr Rheumatol Rep Volume: 15 Page(s): 312
03/01/2013 Authors: Binder E; Edelbauer M -
Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.
Am J Psychiatry Volume: 170 Page(s): 207 - 217
02/01/2013 Authors: GENDEP Investigators; MARS Investigators; STAR*D Investigators -
Gene-environment interactions in major depressive disorder.
Can J Psychiatry Volume: 58 Page(s): 76 - 83
02/01/2013 Authors: Klengel T; Binder EB -
Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner.
Psychoneuroendocrinology Volume: 38 Page(s): 84 - 93
01/01/2013 Authors: Bourke CH; Raees MQ; Malviya S; Bradburn CA; Binder EB; Neigh GN -
Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions.
Nat Neurosci Volume: 16 Page(s): 33 - 41
01/01/2013 Authors: Klengel T; Mehta D; Anacker C; Rex-Haffner M; Pruessner JC; Pariante CM; Pace TWW; Mercer KB; Mayberg HS; Bradley B -
Differential Genetic and Epigenetic Regulation of catechol-O-methyltransferase is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder.
Front Behav Neurosci Volume: 7 Page(s): 30
01/01/2013 Authors: Norrholm SD; Jovanovic T; Smith AK; Binder E; Klengel T; Conneely K; Mercer KB; Davis JS; Kerley K; Winkler J -
Rare variants in TMEM132D in a case-control sample for panic disorder.
Am J Med Genet B Neuropsychiatr Genet Volume: 159B Page(s): 896 - 907
12/01/2012 Authors: Quast C; Altmann A; Weber P; Arloth J; Bader D; Heck A; Pfister H; Mller-Myhsok B; Erhardt A; Binder EB -
Convergent animal and human evidence suggests the activin/inhibin pathway to be involved in antidepressant response.
Transl Psychiatry Volume: 2 Page(s): e177
10/23/2012 Authors: Ganea K; Menke A; Schmidt MV; Lucae S; Rammes G; Liebl C; Harbich D; Sterlemann V; Storch C; Uhr M -
A beginners guide to SNP calling from high-throughput DNA-sequencing data.
Hum Genet Volume: 131 Page(s): 1541 - 1554
10/01/2012 Authors: Altmann A; Weber P; Bader D; Preuss M; Binder EB; Mller-Myhsok B -
Dissecting the genetic heterogeneity of depression through age at onset.
Am J Med Genet B Neuropsychiatr Genet Volume: 159B Page(s): 859 - 868
10/01/2012 Authors: Power RA; Keers R; Ng MY; Butler AW; Uher R; Cohen-Woods S; Ising M; Craddock N; Owen MJ; Korszun A -
Meta-analysis argues for a female-specific role of MAOA-uVNTR in panic disorder in four European populations.
Am J Med Genet B Neuropsychiatr Genet Volume: 159B Page(s): 786 - 793
10/01/2012 Authors: Reif A; Weber H; Domschke K; Klauke B; Baumann C; Jacob CP; Strhle A; Gerlach AL; Alpers GW; Pauli P -
The genetic basis of mood and anxiety disorders - changing paradigms.
Biol Mood Anxiety Disord Volume: 2 Page(s): 17
10/01/2012 Authors: Binder EB -
A common TPH2 haplotype regulates the neural processing of a cognitive control demand.
Am J Med Genet B Neuropsychiatr Genet Volume: 159B Page(s): 829 - 840
10/01/2012 Authors: Kennedy AP; Binder EB; Bowman D; Harenski K; Ely T; Cisler JM; Tripathi SP; VanNess S; Kilts CD -
Replication and meta-analysis of TMEM132D gene variants in panic disorder.
Transl Psychiatry Volume: 2 Page(s): e156
09/04/2012 Authors: Erhardt A; Akula N; Schumacher J; Czamara D; Karbalai N; Mller-Myhsok B; Mors O; Borglum A; Kristensen AS; Woldbye DPD -
Genetic variants in the tryptophan hydroxylase 2 gene (TPH2) and depression during and after pregnancy.
J Psychiatr Res Volume: 46 Page(s): 1109 - 1117
09/01/2012 Authors: Fasching PA; Faschingbauer F; Goecke TW; Engel A; Hberle L; Seifert A; Voigt F; Amann M; Rebhan D; Burger P -
Predictors of remission in depression to individual and combined treatments (PReDICT): study protocol for a randomized controlled trial.
Trials Volume: 13 Page(s): 106
07/09/2012 Authors: Dunlop BW; Binder EB; Cubells JF; Goodman MM; Kelley ME; Kinkead B; Kutner M; Nemeroff CB; Newport DJ; Owens MJ -
Depression and anxiety symptoms among women who carry the FMR1 premutation: impact of raising a child with fragile X syndrome is moderated by CRHR1 polymorphisms.
Am J Med Genet B Neuropsychiatr Genet Volume: 159B Page(s): 549 - 559
07/01/2012 Authors: Hunter JE; Leslie M; Novak G; Hamilton D; Shubeck L; Charen K; Abramowitz A; Epstein MP; Lori A; Binder E -
Regulation of mRNA expression encoding chaperone and co-chaperone proteins of the glucocorticoid receptor in peripheral blood: association with depressive symptoms during pregnancy.
Psychol Med Volume: 42 Page(s): 943 - 956
05/01/2012 Authors: Katz ER; Stowe ZN; Newport DJ; Kelley ME; Pace TW; Cubells JF; Binder EB -
Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients.
Neuropsychopharmacology Volume: 37 Page(s): 1455 - 1464
05/01/2012 Authors: Menke A; Arloth J; Ptz B; Weber P; Klengel T; Mehta D; Gonik M; Rex-Haffner M; Rubel J; Uhr M -
Allele Variations in Fkbp5 and Attention Bias for Threat: Evidence for a Novel Behavioral and Neural Response Phenotype
Volume: 71 Page(s): 149S - 149S
04/15/2012 Authors: Fani N; Almli L; Binder E; Ressler KJ -
Identification of common variants associated with human hippocampal and intracranial volumes.
Nat Genet Volume: 44 Page(s): 552 - 561
04/15/2012 Authors: Stein JL; Medland SE; Vasquez AA; Hibar DP; Senstad RE; Winkler AM; Toro R; Appel K; Bartecek R; Bergmann -
Polymorphisms within the metabotropic glutamate receptor 1 gene are associated with depression phenotypes.
Psychoneuroendocrinology Volume: 37 Page(s): 565 - 575
04/01/2012 Authors: Menke A; Smann P; Kloiber S; Czamara D; Lucae S; Hennings J; Heck A; Kohli MA; Czisch M; Mller-Myhsok B -
The role of endogenous neurotensin in psychostimulant-induced disruption of prepulse inhibition and locomotion.
Schizophr Res Volume: 136 Page(s): 88 - 95
04/01/2012 Authors: Cceda R; Binder EB; Kinkead B; Nemeroff CB -
Low cortisol and risk and resilience to stress-related psychiatric disorders.
Biol Psychiatry Volume: 71 Page(s): 282 - 283
02/15/2012 Authors: Binder EB; Holsboer F -
The 5-HTTLPR polymorphism modulates the influence on environmental stressors on peripartum depression symptoms.
J Affect Disord Volume: 136 Page(s): 1192 - 1197
02/01/2012 Authors: Mehta D; Quast C; Fasching PA; Seifert A; Voigt F; Beckmann MW; Faschingbauer F; Burger P; Ekici AB; Kornhuber J -
Genome-wide association study of antidepressant treatment-emergent suicidal ideation.
Neuropsychopharmacology Volume: 37 Page(s): 797 - 807
02/01/2012 Authors: Menke A; Domschke K; Czamara D; Klengel T; Hennings J; Lucae S; Baune BT; Arolt V; Mller-Myhsok B; Holsboer F -
Gene environment vulnerability factors for PTSD: the HPA-axis.
Neuropharmacology Volume: 62 Page(s): 654 - 662
02/01/2012 Authors: Mehta D; Binder EB -
Peripheral blood gene expression: it all boils down to the RNA collection tubes.
BMC Res Notes Volume: 5 Page(s): 1
01/04/2012 Authors: Menke A; Rex-Haffner M; Klengel T; Binder EB; Mehta D -
Emerging methods in the molecular biology of neuropsychiatric disorders.
Handb Clin Neurol Volume: 106 Page(s): 191 - 209
01/01/2012 Authors: Binder EB; Ressler KJ -
Epigenetics, depression and antidepressant treatment.
Curr Pharm Des Volume: 18 Page(s): 5879 - 5889
01/01/2012 Authors: Menke A; Klengel T; Binder EB -
Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics.
Exp Neurol Volume: 233 Page(s): 102 - 111
01/01/2012 Authors: Heim C; Binder EB -
Posttraumatic stress disorder subtypes invalid.
Arch Gen Psychiatry Volume: 68 Page(s): 978
09/01/2011 Authors: Carroll BJ -
Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies.
Arch Gen Psychiatry Volume: 68 Page(s): 901 - 910
09/01/2011 Authors: Mehta D; Gonik M; Klengel T; Rex-Haffner M; Menke A; Rubel J; Mercer KB; Ptz B; Bradley B; Holsboer F -
A follow-up case-control association study of tractable (druggable) genes in recurrent major depression.
Am J Med Genet B Neuropsychiatr Genet Volume: 156B Page(s): 640 - 650
09/01/2011 Authors: Schosser A; Gaysina D; Cohen-Woods S; Domenici E; Perry J; Tozzi F; Korszun A; Gunasinghe C; Gray J; Jones L -
Neuropeptide S receptor gene--converging evidence for a role in panic disorder.
Mol Psychiatry Volume: 16 Page(s): 938 - 948
09/01/2011 Authors: Domschke K; Reif A; Weber H; Richter J; Hohoff C; Ohrmann P; Pedersen A; Bauer J; Suslow T; Kugel H -
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor (vol 470, pg 492, 2011)
NATURE Volume: 477 Page(s): 120 - 120
09/01/2011 Authors: Ressler KJ; Mercer KB; Bradley B; Jovanovic T; Mahan A; Kerley K; Norrholm SD; Kilaru V; Smith AK; Myers AJ -
Use of peripheral blood expression profiles to identify biomarkers for peripartum depression
Volume: 21 Page(s): S242 - S242
09/01/2011 Authors: Mehta D; Kraus L; Rex-Haffner M; Newport J; Stowe Z; Binder E -
vipR: variant identification in pooled DNA using R.
Bioinformatics Volume: 27 Page(s): i77 - i84
07/01/2011 Authors: Altmann A; Weber P; Quast C; Rex-Haffner M; Binder EB; Mller-Myhsok B -
Association between childhood maltreatment and adult emotional dysregulation: moderation by oxytocin receptor gene
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY Volume: 20 Page(s): S90 - S90
06/01/2011 Authors: Heim C; Westen D; Jovanovic T; Binder EB; Crain D; Wingo A; Bradley B -
TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies.
Mol Psychiatry Volume: 16 Page(s): 647 - 663
06/01/2011 Authors: Erhardt A; Czibere L; Roeske D; Lucae S; Unschuld PG; Ripke S; Specht M; Kohli MA; Kloiber S; Ising M -
Sex-Dependent Influence of a Functional Polymorphism in Steroid 5-alpha-Reductase Type 2 (SRD5a2) on Risk for Post-Traumatic Stress Disorder
Volume: 69 Page(s): 58S - 58S
05/01/2011 Authors: Gillespie CF; Mercer K; Kerley K; Weiss T; Smith AK; Bradley B; Phifer J; Schwartz AC; Tang Y; Cubellss JF -
Association between childhood maltreatment and adult emotional dysregulation in a low-income, urban, African American sample: moderation by oxytocin receptor gene.
Dev Psychopathol Volume: 23 Page(s): 439 - 452
05/01/2011 Authors: Bradley B; Westen D; Mercer KB; Binder EB; Jovanovic T; Crain D; Wingo A; Heim C -
The neuronal transporter gene SLC6A15 confers risk to major depression.
Neuron Volume: 70 Page(s): 252 - 265
04/28/2011 Authors: Kohli MA; Lucae S; Saemann PG; Schmidt MV; Demirkan A; Hek K; Czamara D; Alexander M; Salyakina D; Ripke S -
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor.
Nature Volume: 470 Page(s): 492 - 497
02/24/2011 Authors: Ressler KJ; Mercer KB; Bradley B; Jovanovic T; Mahan A; Kerley K; Norrholm SD; Kilaru V; Smith AK; Myers AJ -
Expression and regulation of the Fkbp5 gene in the adult mouse brain.
PLoS One Volume: 6 Page(s): e16883
02/09/2011 Authors: Scharf SH; Liebl C; Binder EB; Schmidt MV; Mller MB -
Glucocorticoids as predictors of treatment response in depression.
Harv Rev Psychiatry Volume: 19 Page(s): 125 - 143
01/01/2011 Authors: Horstmann S; Binder EB -
Genomewide association scan of suicidal thoughts and behaviour in major depression.
PLoS One Volume: 6 Page(s): e20690
01/01/2011 Authors: Schosser A; Butler AW; Ising M; Perroud N; Uher R; Ng MY; Cohen-Woods S; Craddock N; Owen MJ; Korszun A -
Tolerability of the dexamethasone-corticotropin releasing hormone test in major depressive disorder.
J Psychiatr Res Volume: 45 Page(s): 24 - 28
01/01/2011 Authors: Dunlop BW; Betancourt Y; Binder EB; Heim C; Holsboer F; Ising M; McKenzie M; Mletzko T; Pfister H; Nemeroff CB -
Using gene-environment interactions to target personalized treatment in mood disorder.
Per Med Volume: 8 Page(s): 23 - 34
01/01/2011 Authors: Klengel T; Binder EB -
Individual stress vulnerability is predicted by short-term memory and AMPA receptor subunit ratio in the hippocampus.
J Neurosci Volume: 30 Page(s): 16949 - 16958
12/15/2010 Authors: Schmidt MV; Trmbach D; Weber P; Wagner K; Scharf SH; Liebl C; Datson N; Namendorf C; Gerlach T; Khne C -
The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology.
Clin Lab Med Volume: 30 Page(s): 865 - 891
12/01/2010 Authors: Martin EI; Ressler KJ; Binder E; Nemeroff CB -
Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression.
Biol Psychiatry Volume: 68 Page(s): 578 - 585
09/15/2010 Authors: Rietschel M; Mattheisen M; Frank J; Treutlein J; Degenhardt F; Breuer R; Steffens M; Mier D; Esslinger C; Walter H -
Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression.
Mol Psychiatry Volume: 15 Page(s): 736 - 747
07/01/2010 Authors: Kloiber S; Kohli MA; Brueckl T; Ripke S; Ising M; Uhr M; Menke A; Unschuld PG; Horstmann S; Salyakina D -
A serotonin transporter gene polymorphism predicts peripartum depressive symptoms in an at-risk psychiatric cohort.
J Psychiatr Res Volume: 44 Page(s): 640 - 646
07/01/2010 Authors: Binder EB; Newport DJ; Zach EB; Smith AK; Deveau TC; Altshuler LL; Cohen LS; Stowe ZN; Cubells JF -
The CRF system, stress, depression and anxiety-insights from human genetic studies.
Mol Psychiatry Volume: 15 Page(s): 574 - 588
06/01/2010 Authors: Binder EB; Nemeroff CB -
Gender-specific association of galanin polymorphisms with HPA-axis dysregulation, symptom severity, and antidepressant treatment response.
Neuropsychopharmacology Volume: 35 Page(s): 1583 - 1592
06/01/2010 Authors: Unschuld PG; Ising M; Roeske D; Erhardt A; Specht M; Kloiber S; Uhr M; Mller-Myhsok B; Holsboer F; Binder EB -
FKBP5-A Common Candidate Gene for Stress-Related Psychiatric Disorders?
Volume: 67 Page(s): 107S - 108S
05/01/2010 Authors: Binder EB -
Convergent Evidence for the Genetics of Antidepressant Treatment Response and Side Effect Profiles: Data from the MARS and STAR(star)D Cohorts
Volume: 67 Page(s): 194S - 194S
05/01/2010 Authors: Binder EB -
FKBP5 Polymorphism and Childhood Trauma are Associated with Impaired Fear Inhibition
Volume: 67 Page(s): 114S - 114S
05/01/2010 Authors: Jovanovic T; Norrholm SD; Binder E; Cubells J; Mercer K; Duncan E; Davis M; Bradley B; Ressler K -
Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms.
Am J Med Genet B Neuropsychiatr Genet Volume: 153B Page(s): 812 - 824
04/05/2010 Authors: Ressler KJ; Bradley B; Mercer KB; Deveau TC; Smith AK; Gillespie CF; Nemeroff CB; Cubells JF; Binder EB -
Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients.
Arch Gen Psychiatry Volume: 67 Page(s): 348 - 359
04/01/2010 Authors: Kohli MA; Salyakina D; Pfennig A; Lucae S; Horstmann S; Menke A; Kloiber S; Hennings J; Bradley BB; Ressler KJ -
Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response.
Arch Gen Psychiatry Volume: 67 Page(s): 369 - 379
04/01/2010 Authors: Binder EB; Owens MJ; Liu W; Deveau TC; Rush AJ; Trivedi MH; Fava M; Bradley B; Ressler KJ; Nemeroff CB -
Gene expression studies in major depression.
Curr Psychiatry Rep Volume: 12 Page(s): 135 - 144
04/01/2010 Authors: Mehta D; Menke A; Binder EB -
Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment.
Neuropsychopharmacology Volume: 35 Page(s): 727 - 740
02/01/2010 Authors: Horstmann S; Lucae S; Menke A; Hennings JM; Ising M; Roeske D; Mller-Myhsok B; Holsboer F; Binder EB -
Pharmacogenomics
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01/01/2010 Authors: Debnath M; Prasad GBKS; Bisen PS -
Early, maltreatment, adrenal regulation, and adult depression among rural Nepali: gene-environment interactions in life history.
Page(s): 247 - 248
01/01/2010 Authors: Worthman CM; Kohrt BA; Ressler KJ; Binder EB -
Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders.
Am J Med Genet B Neuropsychiatr Genet Volume: 150B Page(s): 1100 - 1109
12/05/2009 Authors: Unschuld PG; Ising M; Specht M; Erhardt A; Ripke S; Heck A; Kloiber S; Straub V; Brueckl T; Mller-Myhsok B -
The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders.
Psychoneuroendocrinology Volume: 34 Suppl 1 Page(s): S186 - S195
12/01/2009 Authors: Binder EB -
Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment.
Mol Psychiatry Volume: 14 Page(s): 1095 - 1104
12/01/2009 Authors: Bull SJ; Huezo-Diaz P; Binder EB; Cubells JF; Ranjith G; Maddock C; Miyazaki C; Alexander N; Hotopf M; Cleare AJ -
Pharmacogenetics of antidepressant treatment outcome - Results from a genome-wide multilocus analysis including clinical predictors
Volume: 73 Page(s): 665 - 666
11/01/2009 Authors: Ising M; Lucae S; Binder EB; Bettecken T; Uhr M; Ripke S; Kohli MA; Hennings J; Horstmann S; Kloiber S -
Pharmacogenomics of antidepressant drugs.
Pharmacol Ther Volume: 124 Page(s): 57 - 73
10/01/2009 Authors: Horstmann S; Binder EB -
The neuronal transporter gene SLC6A15 confers risk to major depression
Volume: 42 Page(s): 230 - 230
09/01/2009 Authors: Lucae S; Kohli MA; Schmidt M; Saemann PG; Demirkan A; Hek K; Salyakina D; Ripke S; Roeske D; van Duijn CM -
A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression.
Arch Gen Psychiatry Volume: 66 Page(s): 966 - 975
09/01/2009 Authors: Ising M; Lucae S; Binder EB; Bettecken T; Uhr M; Ripke S; Kohli MA; Hennings JM; Horstmann S; Kloiber S -
The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology.
Psychiatr Clin North Am Volume: 32 Page(s): 549 - 575
09/01/2009 Authors: Martin EI; Ressler KJ; Binder E; Nemeroff CB -
Successful treatment of severe juvenile microscopic polyangiitis with rituximab.
Clin Rheumatol Volume: 28 Page(s): 997 - 999
08/01/2009 Authors: Brunner J; Freund M; Prelog M; Binder E; Sailer-Hoeck M; Jungraithmayr T; Huemer C; Sergi C; Zimmerhackl LB -
The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders.
J Neural Transm (Vienna) Volume: 116 Page(s): 649 - 657
06/01/2009 Authors: Thoeringer CK; Ripke S; Unschuld PG; Lucae S; Ising M; Bettecken T; Uhr M; Keck ME; Mueller-Myhsok B; Holsboer F -
Polymorphisms in CRHR1 Moderate the Effects of 5-HTTLPR x Child Abuse Interactions On Adult Depression
Volume: 65 Page(s): 227S - 227S
04/15/2009 Authors: Ressler KJ; Bradley B; Gillespie CF; Cubells J; Nemeroff CB; Binder E -
Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project.
J Psychiatr Res Volume: 43 Page(s): 215 - 229
01/01/2009 Authors: Hennings JM; Owashi T; Binder EB; Horstmann S; Menke A; Kloiber S; Dose T; Wollweber B; Spieler D; Messer T -
Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene.
Front Behav Neurosci Volume: 3 Page(s): 41
01/01/2009 Authors: Heim C; Bradley B; Mletzko TC; Deveau TC; Musselman DL; Nemeroff CB; Ressler KJ; Binder EB -
HPA-axis regulation at in-patient admission is associated with antidepressant therapy outcome in male but not in female depressed patients.
Psychoneuroendocrinology Volume: 34 Page(s): 99 - 109
01/01/2009 Authors: Binder EB; Knzel HE; Nickel T; Kern N; Pfennig A; Majer M; Uhr M; Ising M; Holsboer F -
Genetics and Genomics
Page(s): 81 - 104
01/01/2009 Authors: Binder EB; Cubells JF -
Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder.
Am J Med Genet B Neuropsychiatr Genet Volume: 147B Page(s): 1196 - 1204
10/05/2008 Authors: Keck ME; Kern N; Erhardt A; Unschuld PG; Ising M; Salyakina D; Mller MB; Knorr CC; Lieb R; Hohoff C -
Childhood trauma alters the expression of the glucocorticoid receptor co-chaperone BAG1
Volume: 11 Page(s): 287 - 288
07/01/2008 Authors: Deveau T; Heim C; Mletzko T; Cubells JF; Nemeroff C; Binder EB -
Gender dependent differences in glucocorticoid receptor sensitivity and mRNA levels of glucocorticoid receptor co-chaperone proteins in college-aged meditators
Volume: 11 Page(s): 220 - 220
07/01/2008 Authors: Katz E; Binder EB; Cubells JF; Pace TWW; Raison CL -
Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression
Volume: 11 Page(s): 109 - 109
07/01/2008 Authors: Kloeber S; Kohli M; Brueckl T; Ripke S; Ising M; Uhr M; Menke A; Mueller-Myhsok B; Holsboer F; Binder EB -
Genetic markers within glutamate receptors associated with antidepressant treatment-emergent suicidal ideation.
Am J Psychiatry Volume: 165 Page(s): 917 - 918
07/01/2008 Authors: Menke A; Lucae S; Kloiber S; Horstmann S; Bettecken T; Uhr M; Ripke S; Ising M; Mller-Myhsok B; Holsboer F -
Genetic association analysis of dopamine-related genes with cocaine-induced psychosis
Volume: 106 Page(s): 34 - 34
07/01/2008 Authors: Tang Y; Binder EB; Kranzler HR; Gelernter J; Houston M; Caceda R; Kinkead B; Nemeroff CB; Cubells JF -
Risk for adult posttraumatic stress disorder is predicted by child abuse and FKBP5, a gene regulating stress-responsiveness
Volume: 63 Page(s): 174S - 174S
04/01/2008 Authors: Gillespie CF; Bradley RG; Liu W; Epstein MR; Deveau TC; Tang Y; Heim CM; Nemeroff CB; Schwartz AC; Cubells JF -
Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults.
JAMA Volume: 299 Page(s): 1291 - 1305
03/19/2008 Authors: Binder EB; Bradley RG; Liu W; Epstein MP; Deveau TC; Mercer KB; Tang Y; Gillespie CF; Heim CM; Nemeroff CB -
Association of polymorphisms in the angiotensin-converting enzyme gene with syndromal panic attacks.
Mol Psychiatry Volume: 13 Page(s): 242 - 243
03/01/2008 Authors: Erhardt A; Lucae S; Kern N; Unschuld PG; Ising M; Lieb R; Uhr M; Hohoff C; Deckert J; Bandelow B -
Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene.
Arch Gen Psychiatry Volume: 65 Page(s): 190 - 200
02/01/2008 Authors: Bradley RG; Binder EB; Epstein MP; Tang Y; Nair HP; Liu W; Gillespie CF; Berg T; Evces M; Newport DJ -
Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression.
Neuron Volume: 57 Page(s): 203 - 209
01/24/2008 Authors: Uhr M; Tontsch A; Namendorf C; Ripke S; Lucae S; Ising M; Dose T; Ebinger M; Rosenhagen M; Kohli M -
Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder.
J Affect Disord Volume: 105 Page(s): 177 - 184
01/01/2008 Authors: Unschuld PG; Ising M; Erhardt A; Lucae S; Kohli M; Kloiber S; Salyakina D; Thoeringer CK; Kern N; Lieb R -
Addictions biology: haplotype-based analysis for 130 candidate genes on a single array.
Alcohol Alcohol Volume: 43 Page(s): 505 - 515
01/01/2008 Authors: Hodgkinson CA; Yuan Q; Xu K; Shen P-H; Heinz E; Lobos EA; Binder EB; Cubells J; Ehlers CL; Gelernter J -
Association of a Met88Val diazepam binding inhibitor (DBI) gene polymorphism and anxiety disorders with panic attacks.
J Psychiatr Res Volume: 41 Page(s): 579 - 584
10/01/2007 Authors: Thoeringer CK; Binder EB; Salyakina D; Erhardt A; Ising M; Unschuld PG; Kern N; Lucae S; Brueckl TM; Mueller MB -
Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders.
J Affect Disord Volume: 101 Page(s): 159 - 168
08/01/2007 Authors: Erhardt A; Lucae S; Unschuld PG; Ising M; Kern N; Salyakina D; Lieb R; Uhr M; Binder EB; Keck ME -
Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression - a potential biomarker?
Biol Psychiatry Volume: 62 Page(s): 47 - 54
07/01/2007 Authors: Ising M; Horstmann S; Kloiber S; Lucae S; Binder EB; Kern N; Knzel HE; Pfennig A; Uhr M; Holsboer F -
Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder.
Am J Med Genet B Neuropsychiatr Genet Volume: 144B Page(s): 424 - 429
06/05/2007 Authors: Unschuld PG; Ising M; Erhardt A; Lucae S; Kloiber S; Kohli M; Salyakina D; Welt T; Kern N; Lieb R -
The co-chaperone FKBP5, stress hormone system regulation and antidepressant drug response
Volume: 61 Page(s): 106S - 106S
04/15/2007 Authors: Binder EB -
MRNA levels of BCL2-associated athanogene (BAG1) change during pregnancy and may be associated with glucocorticoid receptor (GR) sensitivity in a high-risk population for periparturn depression
Volume: 61 Page(s): 6S - 6S
04/15/2007 Authors: Katz ER; Deveau TC; Newport DJ; Stowe ZN; Cubells JF; Binder EB -
Genetic variants in genes regulating the corticotropin releasing hormone (CRH) system and response to citalopram in the STAR*D sample
Volume: 61 Page(s): 172S - 172S
04/15/2007 Authors: Binder EB; Owens MJ; Liu W; Fava M; Rush AJ; Trivedi MH; Cubells JF; Nemeroff CB -
Novel promoter variant in the neurotensin gene is protective against cocaine-induced psychosis in African American subjects
Volume: 61 Page(s): 205S - 205S
04/15/2007 Authors: Binder EB; Houston MJ; Caseda R; Tang Y-L; Kinkead B; Deveau TC; Gelernter J; Kranzler HR; Nemeroff CB; Cubells JF -
Pharmacogenetic and pharmacogenomic keys to medical decision making in depression
Volume: 61 Page(s): 3S - 4S
04/15/2007 Authors: Kirchheiner J; Adli M; Keck ME; Binder EB -
CRHR1 haplotypes moderate effects of early life stress (ELS) on adult depression
Volume: 61 Page(s): 232S - 232S
04/15/2007 Authors: Ressler KJ; Binder EB; Bradley RG; Tang Y; Liu W; Gillespie CF; Heim CM; Schwartz A; Nemeroff CB; Cubelis JF -
ISG12 regulates activity of nuclear receptors thereby modulating the vascular response to injury
Volume: 21 Page(s): A903 - A904
04/01/2007 Authors: Papac-Milicevic N; Ryban L; Zaujec J; Binder C; Breuss J; Binder E; Uhrin P; Binder B -
Changes in the hypothalamic-pituitary-adrenal axis and leptin levels during antidepressant treatment.
Neuropsychobiology Volume: 55 Page(s): 28 - 35
01/01/2007 Authors: Himmerich H; Zimmermann P; Ising M; Kloiber S; Lucae S; Kunzel HE; Binder EB; Holsboer F; Uhr M -
Stress results in region specific decreases in expression of angiogenic factors in the brain
Volume: 31 Page(s): S161 - S161
12/01/2006 Authors: Neigh GN; Binder EB; Plotsky PM; Owens MJ; Taylor WR; Nemeroff CB -
Lack of physiological regulation of the expression of co-chaperones of the glucocorticoid receptor in periparturn depression
Volume: 31 Page(s): S135 - S135
12/01/2006 Authors: Katz ER; Deveau TC; Capello CF; Owens MJ; Newport DJ; Stowe ZN; Cubells JF; Binder EB -
Regulation of the hypothalamic-pituitary-adrenocortical system in patients with panic disorder.
Neuropsychopharmacology Volume: 31 Page(s): 2515 - 2522
11/01/2006 Authors: Erhardt A; Ising M; Unschuld PG; Kern N; Lucae S; Ptz B; Uhr M; Binder EB; Holsboer F; Keck ME -
Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism.
Mol Psychiatry Volume: 11 Page(s): 1003 - 1015
11/01/2006 Authors: Baghai TC; Binder EB; Schule C; Salyakina D; Eser D; Lucae S; Zwanzger P; Haberger C; Zill P; Ising M -
Regulation of the activity of nuclear receptors by the interferon inducible gene 12 modulates the vascular response injury
Volume: 114 Page(s): 178 - 178
10/31/2006 Authors: Papac-Milicevic N; Ryban L; Zaujec J; Breuss JM; Binder CJ; Binder EB; Uhrin P; Binder BR -
Successful antidepressant therapy restores the disturbed interplay between TNF-alpha system and HPA axis.
Biol Psychiatry Volume: 60 Page(s): 882 - 888
10/15/2006 Authors: Himmerich H; Binder EB; Knzel HE; Schuld A; Lucae S; Uhr M; Pollmcher T; Holsboer F; Ising M -
Co-chaperones of the glucocorticoid receptor and depression during pregnancy
Volume: 141B Page(s): 710 - 711
10/05/2006 Authors: Katz E; Binder E; Deveau T; Newport J; Stowe Z; Cubells J; Nemeroff C -
Association of polymorphisms in P2RX7 and CAMKKB with anxiety disorders
Volume: 141B Page(s): 740 - 741
10/05/2006 Authors: Erhardt A; Lucae S; Unschuld PG; Ising M; Kern N; Salyakina D; Lieb R; Uhr M; Binder E; Keck ME -
P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder
Volume: 141B Page(s): 740 - 740
10/05/2006 Authors: Lucae S; Salyakina D; Barden N; Harvey M; Gagne B; Labbe M; Binder E; Uhr M; Paez-Pereda M; Sillaber I -
The interferon inducible gene 12 (ISG12), a novel factor modulating the vascular response to injury
Volume: 45 Page(s): 186 - 186
09/01/2006 Authors: Milicevic NP; Ryban L; Zaujec J; Binder CJ; Breuss JM; Binder EB; Uhrin P; Binder BR -
P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder.
Hum Mol Genet Volume: 15 Page(s): 2438 - 2445
08/15/2006 Authors: Lucae S; Salyakina D; Barden N; Harvey M; Gagn B; Labb M; Binder EB; Uhr M; Paez-Pereda M; Sillaber I -
Co-chaperones of the glucocorticoid receptor and peripartum depression
Volume: 9 Page(s): S178 - S178
07/01/2006 Authors: Binder E; Deveau T; Katz E; Newport J; Stowe Z; Cubells J -
The interferon inducible gene 12, a novel factor modulating the vascular response to injury
Volume: 7 Page(s): 488 - 488
06/01/2006 Authors: Papac-Milicevic N; Ryban L; Zaujec J; Binder CJ; Breuss JM; Binder EB; Uhrin P; Binder BR -
Toward a reliable distinction between patients with mild cognitive impairment and Alzheimer-type dementia versus major depression.
Biol Psychiatry Volume: 59 Page(s): 858 - 862
05/01/2006 Authors: Post A; Ackl N; Rcker M; Schreiber Y; Binder EB; Ising M; Sonntag A; Holsboer F; Almeida OFX -
Polymorphisms of the glucocorticoid receptor gene and major depression.
Biol Psychiatry Volume: 59 Page(s): 681 - 688
04/15/2006 Authors: van Rossum EFC; Binder EB; Majer M; Koper JW; Ising M; Modell S; Salyakina D; Lamberts SWJ; Holsboer F -
Alleles and a haplotype at DRD3 associate with cocaine-induced psychosis in African-American cocaine-dependent subjects
Volume: 59 Page(s): 138S - 138S
04/15/2006 Authors: Tang YL; Binder EB; Gelernter J; Kranzler HR; Cubells JF -
Association of polymorphism in the neurotensin/neuromedin N preproprotein (NTS) gene with cocaine-induced psychosis
Volume: 59 Page(s): 54S - 54S
04/15/2006 Authors: Binder EB; Tang YL; Gelernter J; Kranzler HR; Nemeroff CB; Cubells JF -
Possible genetic implications of the endo-cannabinoid system in anxiety disorders versus depressive disorders
Volume: 16 Page(s): S88 - S88
03/01/2006 Authors: Erhardt A; Unschuld PG; Lucae S; Ising M; Salyakina D; Puetz B; Mueller-Myhsok B; Binder EB; Holsboer F; Keck ME -
The effect of chronic and acute maternal stress on expression of placental barrier genes in the rat.
Page(s): 134 - 134
01/01/2006 Authors: Chura LR; Stowe ZN; Binder EB; Bacon SJ; Plotsky PM -
Implications for the practice of psychiatry.
Prog Brain Res Volume: 158 Page(s): 275 - 293
01/01/2006 Authors: Binder EB; Nemeroff CB -
Pharmacogenomics and antidepressant drugs.
Ann Med Volume: 38 Page(s): 82 - 94
01/01/2006 Authors: Binder EB; Holsboer F -
Proteomic analysis of the CSF in unmedicated patients with major depressive disorder reveals alterations in suicide attempters.
Eur Arch Psychiatry Clin Neurosci Volume: 255 Page(s): 438 - 440
12/01/2005 Authors: Brunner J; Bronisch T; Uhr M; Ising M; Binder E; Holsboer F; Turck CW -
Neurotensin system genes and susceptibility to cocaine-induced psychosis
Volume: 30 Page(s): S87 - S87
12/01/2005 Authors: Binder EB; Tang Y; Nemeroff CB; Cubells JF -
Genetic implications of the endocannabinoid system in anxiety disorders versus depressive disorders: Is there any evidence for the continuum hypothesis?
Volume: 138B Page(s): 44 - 44
09/05/2005 Authors: Erhardt A; Seaman SR; Lucae S; Unschuld PG; Kern N; Welt T; Ising M; Salyakina D; Putz B; Lieb R -
Ghrelin plasma levels during psychopharmacological treatment
Volume: 38 Page(s): 249 - 249
09/01/2005 Authors: Himmerich H; Fulda S; Kunzel HE; Pfennig A; Dzaja A; Cummings DE; Pollmacher T -
Successful antidepressant therapy restores the disturbed interplay between TNF-alpha system and HPA axis
Volume: 38 Page(s): 249 - 249
09/01/2005 Authors: Himmerich H; Binder EB; Kunzel H; Schuld A; Lucae S; Uhr M; Pollmacher T; Holsboer F; Ising M -
GABA transporter1 (GAT1) inhibition mediates distinct emotional and cognitive processes and represents a possible treatment strategy compensating genetic polymorphisms in panic disorder
Volume: 38 Page(s): 281 - 281
09/01/2005 Authors: Thoeringer CK; Binder EB; Lucae S; Erhardt A; Unschuld PG; Harbich D; Roedel A; Uhr M; Ohl F; Lieb R -
Genetic implications of the endocannabinoid system in anxiety disorders versus depressive disorders: is there any evidence for the continuum hypothesis?
Volume: 38 Page(s): 240 - 240
09/01/2005 Authors: Erhardt A; Seaman SR; Lucae S; Kern N; Unschuld PG; Welt T; Ising M; Salyakina D; Putz B; Lieb R -
Within- and Inter-gene interactions in FKBP5 and GR genes and its association with early response
Volume: 38 Page(s): 274 - 274
09/01/2005 Authors: Salyakina D; Binder EB; Ising M; Uhr M; Lucae S; Muller-Myhsok B -
Polymorphisms in the angiotensin converting enzyme (ACE) gene are associated with unipolar depression, ACE activity and hypercortisolism
Volume: 38 Page(s): 228 - 228
09/01/2005 Authors: Baghai TC; Binder EB; Holsboer F; Rupprecht R; Bondy B -
Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression.
Biol Psychiatry Volume: 58 Page(s): 307 - 314
08/15/2005 Authors: Schumacher J; Jamra RA; Becker T; Ohlraun S; Klopp N; Binder EB; Schulze TG; Deschner M; Schml C; Hfels S -
The combined dexamethasone/CRH test as a potential surrogate marker in depression.
Prog Neuropsychopharmacol Biol Psychiatry Volume: 29 Page(s): 1085 - 1093
07/01/2005 Authors: Ising M; Knzel HE; Binder EB; Nickel T; Modell S; Holsboer F -
Identification of molecules potentially involved in mediating the in vivo actions of the corticotropin-releasing hormone receptor 1 antagonist, NBI30775 (R121919).
Psychopharmacology (Berl) Volume: 180 Page(s): 150 - 158
06/01/2005 Authors: Post A; Ohl F; Almeida OFX; Binder EB; Rcker M; Welt S; Binder E; Holsboer F; Sillaber I -
HPA-axis function regulating genes and treatment response in depression
Volume: 57 Page(s): 155S - 155S
04/15/2005 Authors: Binder EB -
Polymorphisms in FKBP5 are associated with rapid response to antidepressant treatment
Volume: 57 Page(s): 78S - 78S
04/15/2005 Authors: Binder EB -
Hypothalamus-pituitary-adrenal system regulation and suicidal behavior in depression.
Biol Psychiatry Volume: 57 Page(s): 336 - 342
02/15/2005 Authors: Pfennig A; Kunzel HE; Kern N; Ising M; Majer M; Fuchs B; Ernst G; Holsboer F; Binder EB -
Pharmacogenomics.
Handb Exp Pharmacol Page(s): 527 - 546
01/01/2005 Authors: Binder EB; Holsboer F -
Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment.
Nat Genet Volume: 36 Page(s): 1319 - 1325
12/01/2004 Authors: Binder EB; Salyakina D; Lichtner P; Wochnik GM; Ising M; Ptz B; Papiol S; Seaman S; Lucae S; Kohli MA -
Neurotensin receptor antagonist SR 142948A alters Fos expression and extrapyramidal side effect profile of typical and atypical antipsychotic drugs.
Neuropsychopharmacology Volume: 29 Page(s): 2200 - 2207
12/01/2004 Authors: Binder EB; Kinkead B; Owens MJ; Nemeroff CB -
Impaired divided attention predicts delayed response and risk to relapse in subjects with depressive disorders.
Psychol Med Volume: 34 Page(s): 1453 - 1463
11/01/2004 Authors: Majer M; Ising M; Knzel H; Binder EB; Holsboer F; Modell S; Zihl J -
Ziprasidone-related tardive dyskinesia.
Am J Psychiatry Volume: 161 Page(s): 175 - 176
01/01/2004 Authors: Keck ME; Mller MB; Binder EB; Sonntag A; Holsboer F -
Effects of neurotensin receptor antagonism on latent inhibition in Sprague-Dawley rats.
Psychopharmacology (Berl) Volume: 161 Page(s): 288 - 295
05/01/2002 Authors: Binder EB; Gross RE; Nemeroff CB; Kilts CD -
Neurotensin and dopamine interactions.
Pharmacol Rev Volume: 53 Page(s): 453 - 486
12/01/2001 Authors: Binder EB; Kinkead B; Owens MJ; Nemeroff CB -
The role of neurotensin in the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs.
Biol Psychiatry Volume: 50 Page(s): 856 - 872
12/01/2001 Authors: Binder EB; Kinkead B; Owens MJ; Nemeroff CB -
Enhanced neurotensin neurotransmission is involved in the clinically relevant behavioral effects of antipsychotic drugs: evidence from animal models of sensorimotor gating.
J Neurosci Volume: 21 Page(s): 601 - 608
01/15/2001 Authors: Binder EB; Kinkead B; Owens MJ; Kilts CD; Nemeroff CB -
Pharmacogenomics
NURSING CLINICS OF NORTH AMERICA Volume: 35 Page(s): 975 - +
12/01/2000 Authors: Persing BF; Cheek DJ -
Does neurotensin mediate the effects of antipsychotic drugs?
Biol Psychiatry Volume: 46 Page(s): 340 - 351
08/01/1999 Authors: Kinkead B; Binder EB; Nemeroff CB