Publications

• Systems neuroimmunology: current bottlenecks, research priorities and future directions.
  Nat Immunol Volume: 26 Page(s): 325 - 329
  03/01/2025 Authors: Iyer H; Benoist C; Bilbo SD; Boulanger LM; Burton MD; Daniels BP; Deczkowska A; Flajnik MF; Gareau MG; Grace PM
• The single-cell opioid responses in the context of HIV (SCORCH) consortium.
  Mol Psychiatry Volume: 29 Page(s): 3950 - 3961
  12/01/2024 Authors: Ament SA; Campbell RR; Lobo MK; Receveur JP; Agrawal K; Borjabad A; Byrareddy SN; Chang L; Clarke D; Emani P
• All Blood Brain Barrier Cell Types Demonstrate Capability to Influence Differential Tenofovir and Emtricitabine Metabolism and Transport in the Brain.
  ACS Pharmacol Transl Sci Volume: 7 Page(s): 3626 - 3640
  11/08/2024 Authors: Wilkins HN; Knerler SA; Warshanna A; Coln Ortiz R; Haas K; Orsburn BC; Williams DW
• Drug Metabolism and Transport Capacity of Endothelial Cells, Pericytes, and Astrocytes: Implications for CNS Drug Disposition.
  bioRxiv
  08/05/2024 Authors: Wilkins HN; Knerler SA; Warshanna A; Ortiz RC; Haas K; Orsburn BC; Williams DW
• Spatial Heterogeneity of Brain Lipids in SIV-Infected Macaques Treated with Antiretroviral Therapy.
  J Am Soc Mass Spectrom Volume: 35 Page(s): 185 - 196
  02/07/2024 Authors: White CJ; Gausepohl AM; Wilkins HN; Eberhard CD; Orsburn BC; Williams DW
• Roadmap for the expression of canonical and extended endocannabinoid system receptors and metabolic enzymes in peripheral organs of preclinical animal models.
  Physiol Rep Volume: 12 Page(s): e15947
  02/01/2024 Authors: Rosado-Franco JJ; Ellison AL; White CJ; Price AS; Moore CF; Williams RE; Fridman LB; Weerts EM; Williams DW
• Cocaine regulates antiretroviral therapy CNS access through pregnane-x receptor-mediated drug transporter and metabolizing enzyme modulation at the blood brain barrier.
  Fluids Barriers CNS Volume: 21 Page(s): 5
  01/10/2024 Authors: Coln Ortiz R; Knerler S; Fridman LB; Mercado A; Price A-S; Rosado-Franco JJ; Wilkins H; Flores BR; Orsburn BC; Williams DW
• Cocaine Regulates Antiretroviral Therapy CNS Access Through Pregnane-X Receptor-Mediated Drug Transporter and Metabolizing Enzyme Modulation at the Blood Brain Barrier.
  bioRxiv
  07/29/2023 Authors: Fridman LB; Knerler S; Price A-S; Ortiz RC; Mercado A; Wilkins H; Flores BR; Orsburn BC; Williams DW
• Roadmap For The Expression Of Canonical and Extended Endocannabinoid System Receptors and Proteins in Peripheral Organs of Preclinical Animal Models.
  bioRxiv
  06/22/2023 Authors: Rosado-Franco JJ; Ellison AL; White CJ; Price AS; Moore CF; Williams RE; Fridman LB; Weerts EM; Williams DW
• Juneteenth in STEMM and the barriers to equitable science.
  Cell Volume: 186 Page(s): 2510 - 2517
  06/08/2023 Authors: Mays A; Byars-Winston A; Hinton A; Marshall AG; Kirabo A; August A; Marlin BJ; Riggs B; Tolbert B; Wanjalla C
• Integrase Inhibitors are Associated with Neuropsychiatric Symptoms in Women with HIV.
  J Neuroimmune Pharmacol Volume: 18 Page(s): 1 - 8
  06/01/2023 Authors: Rubin LH; O'Halloran JA; Williams DW; Li Y; Fitzgerald KC; Dastgheyb R; Damron AL; Maki PM; Spence AB; Sharma A
• Orthogonal approaches required to measure proteasome composition and activity in mammalian brain tissue.
  J Biol Chem Volume: 299 Page(s): 104811
  06/01/2023 Authors: Trker F; Bharadwaj RA; Kleinman JE; Weinberger DR; Hyde TM; White CJ; Williams DW; Margolis SS
• Cannabis Use Is Associated With Decreased Antiretroviral Therapy Adherence Among Older Adults With HIV.
  Open Forum Infect Dis Volume: 10 Page(s): ofac699
  01/01/2023 Authors: Manuzak JA; Granche J; Tassiopoulos K; Rower JE; Knox JR; Williams DW; Ellis RJ; Goodkin K; Sharma A; Erlandson KM
• T-cell activation state differentially contributes to neuropsychiatric complications in women with HIV.
  Brain Behav Immun Health Volume: 25 Page(s): 100498
  11/01/2022 Authors: Williams DW; Flores BR; Xu Y; Wang Y; Yu D; Peters BA; Adedimeji A; Wilson TE; Merenstein D; Tien PC
• Plasma microRNAs are associated with domain-specific cognitive function in people with HIV.
  AIDS Volume: 35 Page(s): 1795 - 1804
  09/01/2021 Authors: Massanett Aparicio J; Xu Y; Li Y; Colantuoni C; Dastgheyb R; Williams DW; Asahchop EL; McMillian JM; Power C; Fujiwara E
• Dietary intake is associated with neuropsychological impairment in women with HIV.
  Am J Clin Nutr Volume: 114 Page(s): 378 - 389
  07/01/2021 Authors: Rubin LH; Gustafson DR; Warrior L; Sheira L; Fitzgerald KC; Dastgheyb R; Weber KM; Tien PC; French A; Spence AB
• Higher circulating intermediate monocytes are associated with cognitive function in women with HIV.
  JCI Insight Volume: 6
  06/08/2021 Authors: Veenhuis RT; Williams DW; Shirk EN; Abreu CM; Ferreira EA; Coughlin JM; Brown TT; Maki PM; Anastos K; Berman JW
• Integrase Strand Transfer Inhibitor Start or Switch Impacts Learning in Women With HIV.
  J Acquir Immune Defic Syndr Volume: 86 Page(s): 593 - 599
  04/15/2021 Authors: O'Halloran JA; Wang K; Spence AB; Williams DW; Dastgheyb R; Fitzgerald KC; Kamkwalala AR; Maki PM; Sharma A; Gustafson DR
• Associations between Antiretroviral Drugs on Depressive Symptomatology in Homogenous Subgroups of Women with HIV.
  J Neuroimmune Pharmacol Volume: 16 Page(s): 181 - 194
  03/01/2021 Authors: Williams DW; Li Y; Dastgheyb R; Fitzgerald KC; Maki PM; Spence AB; Gustafson DR; Milam J; Sharma A; Adimora AA
• Associations between Antiretrovirals and Cognitive Function in Women with HIV.
  J Neuroimmune Pharmacol Volume: 16 Page(s): 195 - 206
  03/01/2021 Authors: Rubin LH; Li Y; Fitzgerald KC; Dastgheyb R; Spence AB; Maki PM; Sharma A; Gustafson DR; Milam J; Weber KM
• Sex-specific associations between cerebrospinal fluid inflammatory marker levels and cognitive function in antiretroviral treated people living with HIV in rural Uganda.
  Brain Behav Immun Volume: 93 Page(s): 111 - 118
  03/01/2021 Authors: Vecchio AC; Williams DW; Xu Y; Yu D; Saylor D; Lofgren S; O'Toole R; Boulware DR; Nakasujja N; Nakigozi G
• Starting or Switching to an Integrase Inhibitor-Based Regimen Affects PTSD Symptoms in Women with HIV.
  AIDS Behav Volume: 25 Page(s): 225 - 236
  01/01/2021 Authors: Kamkwalala AR; Wang K; O'Halloran J; Williams DW; Dastgheyb R; Fitzgerald KC; Spence AB; Maki PM; Gustafson DR; Milam J
• Patterns and Predictors of Cognitive Function Among Virally Suppressed Women With HIV.
  Front Neurol Volume: 12 Page(s): 604984
  01/01/2021 Authors: Dastgheyb RM; Buchholz AS; Fitzgerald KC; Xu Y; Williams DW; Springer G; Anastos K; Gustafson DR; Spence AB; Adimora AA
• Editorial: Advances in Understanding NeuroHIV Associated Changes in Neuroimmune Communication in the Combined Anti-retroviral Therapy (cART) Era.
  Front Neurol Volume: 12 Page(s): 763448
  01/01/2021 Authors: Gaskill PJ; Fields JA; Langford DT; Stauch KL; Williams DW
• Brief Report: Higher Peripheral Monocyte Activation Markers Are Associated With Smaller Frontal and Temporal Cortical Volumes in Women With HIV.
  J Acquir Immune Defic Syndr Volume: 84 Page(s): 54 - 59
  05/01/2020 Authors: Kamkwalala AR; Wang X; Maki PM; Williams DW; Valcour VG; Damron A; Tien PC; Weber KM; Cohen MH; Sundermann EE
• Factors Predicting Detrimental Change in Declarative Memory Among Women With HIV: A Study of Heterogeneity in Cognition.
  Front Psychol Volume: 11 Page(s): 548521
  01/01/2020 Authors: Fitzgerald KC; Maki PM; Xu Y; Jin W; Dastgheyb R; Williams DW; Springer G; Anastos K; Gustafson D; Spence AB
• Early Inflammatory Signatures Predict Subsequent Cognition in Long-Term Virally Suppressed Women With HIV.
  Front Integr Neurosci Volume: 14 Page(s): 20
  01/01/2020 Authors: Rubin LH; Xu Y; Norris PJ; Wang X; Dastgheyb R; Fitzgerald KC; Keating SM; Kaplan RC; Maki PM; Anastos K
• Profound immune consequences for young adults infected with HIV perinatally or during childhood: a cautionary tale regarding adherence to antiretroviral therapy.
  AIDS Volume: 33 Page(s): 2251 - 2252
  11/15/2019 Authors: Williams DW; Elahi S
• Specimen Collection for Translational Studies in Hidradenitis Suppurativa.
  Sci Rep Volume: 9 Page(s): 12207
  08/21/2019 Authors: Byrd AS; Dina Y; Okoh UJ; Quartey QQ; Carmona-Rivera C; Williams DW; Kerns ML; Miller RJ; Petukhova L; Naik HB
• CCR2 on Peripheral Blood CD14+CD16+ Monocytes Correlates with Neuronal Damage, HIV-Associated Neurocognitive Disorders, and Peripheral HIV DNA: reseeding of CNS reservoirs?
  J Neuroimmune Pharmacol Volume: 14 Page(s): 120 - 133
  03/01/2019 Authors: Veenstra M; Byrd DA; Inglese M; Buyukturkoglu K; Williams DW; Fleysher L; Li M; Gama L; Len-Rivera R; Calderon TM
• CCR2 Signaling Selectively Regulates IFN-: Role of -Arrestin 2 in IFNAR1 Internalization.
  J Immunol Volume: 202 Page(s): 105 - 118
  01/01/2019 Authors: Williams DW; Askew LC; Jones E; Clements JE
• Collagen deposition in chronic hidradenitis suppurativa: potential role for CD163+ macrophages.
  Br J Dermatol Volume: 179 Page(s): 792 - 794
  09/01/2018 Authors: Byrd AS; Kerns ML; Williams DW; Zarif JC; Rosenberg AZ; Delsante M; Liu H; Dillen CA; Maynard JP; Caffrey JA
• Frontline Science: CXCR7 mediates CD14+CD16+ monocyte transmigration across the blood brain barrier: a potential therapeutic target for NeuroAIDS.
  J Leukoc Biol Volume: 102 Page(s): 1173 - 1185
  11/01/2017 Authors: Veenstra M; Williams DW; Calderon TM; Anastos K; Morgello S; Berman JW
• Dopamine Increases CD14+CD16+ Monocyte Transmigration across the Blood Brain Barrier: Implications for Substance Abuse and HIV Neuropathogenesis.
  J Neuroimmune Pharmacol Volume: 12 Page(s): 353 - 370
  06/01/2017 Authors: Calderon TM; Williams DW; Lopez L; Eugenin EA; Cheney L; Gaskill PJ; Veenstra M; Anastos K; Morgello S; Berman JW
• Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions.
  Sci Signal Volume: 10
  04/04/2017 Authors: Dickens AM; Tovar-Y-Romo LB; Yoo S-W; Trout AL; Bae M; Kanmogne M; Megra B; Williams DW; Witwer KW; Gacias M
• Splenic Damage during SIV Infection: Role of T-Cell Depletion and Macrophage Polarization and Infection.
  Am J Pathol Volume: 186 Page(s): 2068 - 2087
  08/01/2016 Authors: Williams DW; Engle EL; Shirk EN; Queen SE; Gama L; Mankowski JL; Zink MC; Clements JE
• A fully human antibody to gp41 selectively eliminates HIV-infected cells that transmigrated across a model human blood brain barrier.
  AIDS Volume: 30 Page(s): 563 - 572
  02/20/2016 Authors: McFarren A; Lopez L; Williams DW; Veenstra M; Bryan RA; Goldsmith A; Morgenstern A; Bruchertseifer F; Zolla-Pazner S; Gorny MK
• Novel flow cytometric analysis of the blood-brain barrier.
  Cytometry A Volume: 87 Page(s): 897 - 907
  10/01/2015 Authors: Williams DW; Tesfa L; Berman JW
• Dopamine Increases CD14+CD16+Monocyte Transmigration Across the Blood Brain Barrier: Implications for Substance Abuse and HIV Neuropathogenesis
  Volume: 10 Page(s): S62 - S62
  04/01/2015 Authors: Calderon TM; Williams DW; Lopez L; Eugenin EA; Gaskill PJ; Anastos K; Morgello S; Berman JW
• Buprenorphine decreases the CCL2-mediated chemotactic response of monocytes.
  J Immunol Volume: 194 Page(s): 3246 - 3258
  04/01/2015 Authors: Carvallo L; Lopez L; Che F-Y; Lim J; Eugenin EA; Williams DW; Nieves E; Calderon TM; Madrid-Aliste C; Fiser A
• JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individuals.
  J Leukoc Biol Volume: 97 Page(s): 401 - 412
  02/01/2015 Authors: Williams DW; Anastos K; Morgello S; Berman JW
• CCR2 on CD14(+)CD16(+) monocytes is a biomarker of HIV-associated neurocognitive disorders.
  Neurol Neuroimmunol Neuroinflamm Volume: 1 Page(s): e36
  10/01/2014 Authors: Williams DW; Byrd D; Rubin LH; Anastos K; Morgello S; Berman JW
• Dopamine mediated activation of the ADAM17 metalloprotease in CD14+CD16+monocytes: A mechanism for increased monocyte transmigration across the BBB in HIV infected drug abusers
  Volume: 9 Page(s): 8 - 8
  03/01/2014 Authors: Calderon TM; Williams DW; Lopez L; Coley JS; Anastos K; Berman JW
• Monocytes mediate HIV neuropathogenesis: mechanisms that contribute to HIV associated neurocognitive disorders.
  Curr HIV Res Volume: 12 Page(s): 85 - 96
  01/01/2014 Authors: Williams DW; Veenstra M; Gaskill PJ; Morgello S; Calderon TM; Berman JW
• Pannexin1 hemichannels are critical for HIV infection of human primary CD4+ T lymphocytes.
  J Leukoc Biol Volume: 94 Page(s): 399 - 407
  09/01/2013 Authors: Orellana JA; Velasquez S; Williams DW; Sez JC; Berman JW; Eugenin EA
• THE EFFECTS OF DOPAMINE ON CD14+CD16+TRANSMIGRATION ACROSS THE HUMAN BLOOD BRAIN BARRIER AND ITS ROLE IN THE PATHOGENESIS OF NEUROAIDS
  Volume: 8 Page(s): 400 - 400
  04/01/2013 Authors: Williams DW; Calderon TC; Lopez L; Morgello S; Berman JW
• DOPAMINE MEDIATED NEUROINFLAMMATION AND CNS DAMAGE IN THE CONTEXT OF HIV INFECTION: A COMMON MECHANISM OF DRUGS OF ABUSE.
  Volume: 8 Page(s): 439 - 439
  04/01/2013 Authors: Berman JW; Calderon TM; Lopez L; Williams DW; Coley J; Gaskill PJ; Eugenin EA
• DOPAMINE INCREASES CD14+CD16+MONOCYTE TRANSMIGRATION ACROSS THE BBB.
  Volume: 8 Page(s): 409 - 409
  04/01/2013 Authors: Calderon TM; Lopez L; Williams DW; Gaskill PJ; Eugenin EA; Berman JW
• Mechanisms of HIV entry into the CNS: increased sensitivity of HIV infected CD14+CD16+ monocytes to CCL2 and key roles of CCR2, JAM-A, and ALCAM in diapedesis.
  PLoS One Volume: 8 Page(s): e69270
  01/01/2013 Authors: Williams DW; Calderon TM; Lopez L; Carvallo-Torres L; Gaskill PJ; Eugenin EA; Morgello S; Berman JW
• The Effects of Dopamine on Leukocyte Transmigration Across the Human Blood-brain Barrier and its Role in the Pathogenesis of Neuroaids.
  Volume: 7 Page(s): S59 - S59
  04/01/2012 Authors: Williams DW; Calderon TM; Coley JS; Gaskill PJ; Carvallo L; Eugenin EA; Berman JW
• Monocyte maturation, HIV susceptibility, and transmigration across the blood brain barrier are critical in HIV neuropathogenesis.
  J Leukoc Biol Volume: 91 Page(s): 401 - 415
  03/01/2012 Authors: Williams DW; Eugenin EA; Calderon TM; Berman JW
• Characterization of monocyte maturation/differentiation that facilitates their transmigration across the blood-brain barrier and infection by HIV: implications for NeuroAIDS.
  Cell Immunol Volume: 267 Page(s): 109 - 123
  01/01/2011 Authors: Buckner CM; Calderon TM; Willams DW; Belbin TJ; Berman JW